BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| MBCQ | MBCQ is an inhibitor of cGMP-specific phosphodiesterase (PDE5). Synonyms: 4-Quinazolinamine, N-(1,3-benzodioxol-5-ylmethyl)-6-chloro-. Grades: ≥98%. CAS No. 150450-53-6. Molecular formula: C16H12ClN3O2. Mole weight: 313.7. |  |
| MBP146-78 | MBP146-78 is a potent and selective inhibitor of cGMP dependent protein kinases. Synonyms: MBP146-78; MBP146 78; MBP14678; 4-[2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrrol-3-yl]pyridine; 4-(2-(4-fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl)pyridine; P-(FP)-MP-PP. CAS No. 188343-77-3. Molecular formula: C21H22FN3. Mole weight: 335.42. | |
| MC1568 | MC1568 is an impressive and discerning inhibitor extensively employed in the research of a wide array of ailments such as cancer, neurodegeneration and inflammatory maladies. Synonyms: MC-1568; MC 1568; MC1568. CAS No. 852475-26-4. Molecular formula: C17H15FN2O3. Mole weight: 314.311. | |
| MC180295 | MC180295 is a potent and selective CDK9-Cyclin T1 inhibitor with IC50 of 5 nM. MC180295 also inhibits GSK-3α and GSK-3&beta. It has a powerful anti-tumor effect. Grades: ≥98% by HPLC. CAS No. 2237942-08-2. Molecular formula: C17H18N4O3S. Mole weight: 358.4. | |
| MCB-613 | MCB-613 is a potent steroid receptor coactivator (SRC) stimulator. Synonyms: MCB 613; MCB613. Grades: 98%. CAS No. 1162656-22-5. Molecular formula: C20H20N2O. Mole weight: 304.39. | |
| MCC-555 | MCC-555, a thiazolidinedion derivative, has been found to be a PPAR agonist that was once studied as hyperglycaemic and hyperlipidaemic. The Phase II trial against Type-2 diabetes mellitus has been already discontinued. Synonyms: Netoglitazone; MCC-555; MCC 555; MCC555; RWJ-241947; RWJ 241947; RWJ241947; isaglitazone; Netoglitazone; UNII-QOV2JZ647A; 5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 161600-01-7. Molecular formula: C21H16FNO3S. Mole weight: 381.42. | |
| MCHB-1 | MCHB-1 is a potent and selective agonist of the human cannabinoid 2 (CB2) receptor with Ki values of 3.7 and 110 nM for CB2 and CB1, respectively. Synonyms: N-Methylcyclohexyl benzimidazole analog 1; 1-(cyclohexylmethyl)-2-(4-ethoxybenzyl)-N,N-diethyl-1h-benzo[d]imidazole-5-carboxamide; 2-(4-ethoxybenzyl)-1-(cyclohexylmethyl)-N,N-diethyl-1H-benzo[d]imidazole-5-carboxamide. Grades: ≥98%. CAS No. 1046140-32-2. Molecular formula: C28H37N3O2. Mole weight: 447.6. | |
| m-Chlorophenylbiguanide hydrochloride | m-Chlorophenylbiguanide hydrochloride is the hydrochloride salt of chlorophenylbiguanide, which is a selective and prototypical potent 5-HT3 serotonin receptor agonist. Synonyms: 1-(3-Chlorophenyl)biguanide hydrochloride; 1-(m-Chlorophenyl)biguanide hydrochloride; N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride; m-CPBG hydrochloride; Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, hydrochloride (1:1); Biguanide, 1-(m-chlorophenyl)-, monohydrochloride; Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, monohydrochloride; N-m-Chlorophenylbiguanide hydrochloride. Grades: ≥98% by HPLC. CAS No. 2113-5-5. Molecular formula: C8H11Cl2N5. Mole weight: 248.11. | |
| Mcl1-IN-1 | Mcl1-IN-1 is a potent Mcl-1-selective inhibitor with IC50 of 2.4 uM, relative to the related Bcl-2 family protein Bcl-xL. Uses: Myeloid cell factor 1 inhibitor. Synonyms: Mcl1-IN-1; Mcl1IN1; Mcl1 IN 1; Mcl1-inhibitor-1; Mcl1 inhibitor 1; {2-[(5-Chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy}acetic acid. Grades: ≥95%. CAS No. 713492-66-1. Molecular formula: C23H18ClN3O4. Mole weight: 435.86. | |
| Mcl1-IN-2 | Mcl1-IN-2, a hydroxyquinoline derivative, is an Mcl-1 inhibitor. Synonyms: Mcl1-IN-2; Mcl1IN2; Mcl1 IN 2; Mcl1-inhibitor-2; Mcl1 inhibitor 2; 7- [ (pyridin-2-yl amino) -thiophen-2-yl methyl ] quinolin-8-olMcl1-IN-2F0388-00637- [ (pyridin-2-yl amino) (thiophen-2-yl ) methyl ] quinolin-8-ol7- ( (pyridin-2-yl amino) (thiophen-2-yl ) methyl ) quinolin-8-olAC1MTHV9Oprea1_135655SCHEMBL154889 79CCG-21482. CAS No. 292057-76-2. Molecular formula: C19H15N3OS. Mole weight: 333.41. | |
| (±)-McN 5652 | (±)-McN 5652 is a potent, orally active 5-HT uptake inhibitor. McN-5652 is characterized by exceptionally high potency as an inhibitor of the uptake of serotonin by rat brain synaptosomes in vitro (Ki approximately 0.6 nM) and ex vivo (ED50 approximately 2 mg/kg p.o.). (±)-McN 5652 is a potent, selective inhibitor of serotonin reuptake in mammalian brain. It potently potentiates 5-HT-induced effects in vivo following oral administration. Its biological activity resides predominantly in the (+)-enantiomer. Synonyms: (±)-McN 5652; (±)-McN5652; (±)-McN-5652; (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline. Grades: ≥98% by HPLC. CAS No. 96795-89-0. Molecular formula: C19H21NS. Mole weight: 295.44. | |
| McN5691 | McN5691, an antihypertensive agent, is a voltage-sensitive calcium channel blocker. Synonyms: N-[2-(3,4-dimethoxyphenyl)ethyl]-4-[5-methoxy-2-(2-phenylethynyl)phenyl]-N-methylbutan-2-amine; McN 5691; McN-5691; N-(2-(3,4-dimethoxyphenyl)ethyl)-5-methoxy-N-dimethyl-2-(phenylethynyl)benzenepropanamine. CAS No. 99254-95-2. Molecular formula: C30H35NO3. Mole weight: 457.6. | |
| McN-A 343 | McN-A 343 is a partial agonist with similar affinity at all five muscarinic acetylcholine receptor subtypes and its relative selectivity depends on a higher efficacy at the M1 (and M4) subtypes. Its selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors. Uses: Nicotinic agonists. Synonyms: [4-(m-Chlorophenylcarbamoyloxy)-2-butynyl]trimethylammonium Chloride; 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium Chloride; m-Chlorocarbanilate (4-Hydroxy-2-butynyl)trimethylammonium Chloride; A 343; McN 343; McN-A 343-11. Grades: ≥99% by HPLC. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. | |
| MD001 | MD001 is a dual peroxisome proliferator-activated receptor PPARα/PPARγ agonist. It increases the transcriptional activity of PPARα and PPARγ, improving the expression of genes associated with β-oxidation and fatty acid and glucose uptake. It significantly improved blood metabolic parameters in db/db mice. Synonyms: MD001; 2254605-76-8; 5,7-dihydroxy-8-methyl-4-phenyl-3-[(E)-3-phenylprop-2-enoyl]chromen-2-one; 5,7-dihydroxy-8-methyl-3-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-4-phenyl-2H-1-benzopyran-2-one; AKOS040754842. Grades: ≥90%. CAS No. 2254605-76-8. Molecular formula: C25H18O5. Mole weight: 398.41. | |
| MD2-IN-1 | MD2-IN-1 is an inhibitor of myeloid differentiation protein 2 (MD2) with a KD of 189 μM for recombinant human MD2 (rhMD2). Synonyms: (2E)-1-(3,4-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One; MDK7229. Grades: 98%. CAS No. 111797-22-9. Molecular formula: C20H22O6. Mole weight: 358.4. | |
| MDL 100009 | MDL 100009 is the S-enantiomer of MDL 100151, which is a selective 5-HT2A antagonist. Synonyms: MDL 100009; MDL100009; MDL-100009; (S)-(2,3-Dimethoxyphenyl){1-[2-(4-fluorophenyl)ethyl]-4-piperidinyl}methanol. Grades: 99%. CAS No. 175673-57-1. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 100151 | MDL 100151 is the racemic MDL 100907 and a selective 5-HT2A antagonist. Synonyms: MDL 100151; MDL-100151; MDL100151; (2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol. Grades: 99%. CAS No. 139290-69-0. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 100907 | MDL 100907 is a selective 5-HT2A receptor antagonist with Ki value of 0.36 nM. It shows antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo. Synonyms: Volinanserin; MDL-100907; MDL 100907; MDL100907; (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol; Volinanserin. Grades: ≥98% by HPLC. CAS No. 139290-65-6. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 105519 | MDL 105519, a ligand selective for the glycine binding site of NMDA receptor, was shown that completely inhibited the binding of [3H]glycine to rat brain membranes with a Ki= 10.9±1.4 nM (n= 6). Inhibits [3H]glycine binding to the NMDA receptor with Kd= 3. Synonyms: MDL-105519; MDL 105519; MDL105519; MDL105,519; MDL-105,519; MDL 105,519; 3-[(E)-2-carboxy-2-phenylethenyl]-4,6-dichloro-1H-indole-2-carboxylic acidMDL 105,519Mdl 105519CHEMBL180427(E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid161230-88-2MDL-105519Lopac-M-216AC1O7G4OM216_SIGMALopac0_000805C1 8H. CAS No. 161230-88-2. Molecular formula: C18H11Cl2NO4. Mole weight: 376.19. | |
| (-)-MDL 105725 | (-)-MDL 105725 is a selective 5-HT2A antagonist, which is a less active metabolite of MDL 100907. Synonyms: (-)-MDL 105725; (-)-MDL105725; (-)-MDL-105725; (S)-3-((1-(4-fluorophenethyl)piperidin-4-yl)(hydroxy)methyl)-2-methoxyphenol. Grades: 98%. CAS No. 311348-81-9. Molecular formula: C21H26FNO3. Mole weight: 359.43. | |
| (+)-MDL 105725 | (+)-MDL 105725 is an active metabolite of MDL 100907, which is a selective 5-HT2A antagonist. Synonyms: (+)-MDL 105725; (+)-MDL105725; (+)-MDL-105725; 3-[(R)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]-hydroxymethyl]-2-methoxyphenol. Grades: 99%. CAS No. 189192-18-5. Molecular formula: C21H26FNO3. Mole weight: 359.43. | |
| (±)-MDL 105725 | (±)-MDL 105725 is an active metabolite of MDL 100907, which is a 5-HT2A receptor antagonist. Synonyms: (±)-MDL 105725; (±)-MDL105725; (±)-MDL-105725. Grades: 99%. CAS No. 1018473-89-6. Molecular formula: C21H26FNO3. Mole weight: 359.43. | |
| MDL 11939 | MDL 11939 is a selective 5-HT2A receptor antagonist. MDL 11939 has anti-arrhythmic activity in anesthetized dogs following myocardial infarction. Synonyms: Glemanserin; MDL 11,939; Mdl 11939; α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol. Grades: ≥99% by HPLC. CAS No. 107703-78-6. Molecular formula: C20H25NO. Mole weight: 295.42. | |
| MDL 201012 | MDL 201012 is a selective M3 muscarinic receptor antagonist used as an antimuscarinic agent. Uses: Antimuscarinic agent. Synonyms: MDL 201012; MDL201012; MDL-201012; 1-cyclobutyl-7-(dimethylamino)-1-hydroxy-1-phenylhept-5-yn-2-one; 5-Heptyn-2-one,1-cyclobutyl-7-(dimethylamino)-1-hydroxy-1-phenyl-, hydrochloride, (-)-. Grades: 98%. CAS No. 136722-45-7. Molecular formula: C19H25NO2. Mole weight: 299.41. | |
| MDL 29951 | MDL-29951 is a novel glycine antagonist of NMDA receptor activation, with Ki of 0.14 μM for [3H]glycine binding in vitro and in vivo. Synonyms: MDL 29951; MDL-29951; MDL29951; MDL 29,951; MDL-29,951; MDL29,951. CAS No. 130798-51-5. Molecular formula: C12H9Cl2NO4. Mole weight: 302.107. | |
| MDL 72222 | MDL 72222 is a 5-HT3 receptor antagonist. Synonyms: MDL72222; MDL 72222; MDL-72222; Tropanyl 3,5-dichlorobenzoate; Bemesetron; endo-3,5-Dichloro-benzoic Acid 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester. Grades: ≥99% by HPLC. CAS No. 40796-97-2. Molecular formula: C15H17Cl2NO2. Mole weight: 314.21. | |
| MDL 72832 hydrochloride | MDL 72832 hydrochloride is a potent ligand at 5-HT1A receptors, with mixed agonist and antagonist properties. Synonyms: MDL 72832 hydrochloride; MDL72832 hydrochloride; MDL-72832 hydrochloride; 8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grades: ≥99% by HPLC. CAS No. 113777-40-5. Molecular formula: C22H30N2O4.HCl. Mole weight: 422.95. | |
| MDL 73005EF hydrochloride | MDL 73005EF hydrochloride is a 5-HT1A receptor antagonist. Synonyms: MDL 73005EF hydrochloride; MDL73005EF hydrochloride; MDL-73005EF hydrochloride; 8-[2-(1,4-Benzodioxan-2-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grades: ≥98% by HPLC. CAS No. 102908-60-1. Molecular formula: C20H26N2O4.HCl. Mole weight: 394.9. | |
| MeBIO | MeBIO, an analog of 6-bromoindirubin-3'-oxime, has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases. MeBIO displays minimal activity against CDK1/Cyclin B, GSK-3 α/β, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). Synonyms: MeBIO; Me-BIO; Me BIO; (2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime; MeBIO; 1-Methyl-6-bromo-indirubin-3'-oxime; Me6BIO. Grades: ≥99% by HPLC. CAS No. 667463-95-8. Molecular formula: C17H12BrN3O2. Mole weight: 370.2. | |
| Mecamylamine hydrochloride | Mecamylamine hydrochloride is a non-competitive nicotinic acetylcholine receptor antagonist with preferential activity at the α3β4 subtype (IC50 = 90-640 nM) compared to α4β2, α3β2, and α7 subtypes (IC50 range from 1-7 μM), previously used to treat hypertension. Synonyms: Inversine; Mecamine hydrochloride Mecamylamine HCl; Mevasin; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride. CAS No. 826-39-1. Molecular formula: C11H21N.HCl. Mole weight: 203.75. | |
| Meclinertant | Meclinertant, a chloroquinolin derivative, has been found to be a Neurotensin receptor antagonist that could be probably effective against schizophrenia and some sorts of drug addiction at some extent. It has been already discontinued by sanofi-aventis for Small cell lung cancer. IC50: 15.3 and 20.4 nM for NTS1 and NTS2 respectively. Synonyms: Meclinertant; SR 48692; SR-48692; Reminertant; SR48692. Grades: 98%. CAS No. 146362-70-1. Molecular formula: C32H31ClN4O5. Mole weight: 587.07. | |
| MEDI0680 | A humanized immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed cell death 1 (PD-1), a transmembrane protein in the Ig superfamily expressed on T cells. MEDI0680 has potential immune checkpoint inhibitory and antineoplastic activities because it binds to and inhibits PD-1 and its downstream signaling pathways. Synonyms: AMP-514; AMP 514; AMP514; MEDI 0680; MEDI-0680; MEDI0680. | |
| MEDI6469 | MEDI6469 is an agonistic monoclonal antibody that binds to and activates a protein in humans called OX40. Because OX40 helps activate the immune system, it is hoped that it has potential immunostimulatory and antineoplastic activities. Synonyms: An agonistic anti-CD134 monoclonal antibody MEDI6469; MEDI 6469; MEDI-6469. | |
| MEDI-8897 | MEDI-8897 is a monoclonal antibody (MAb) used as a long-acting therapy for respiratory syncytial virus (RSV) infections in infants. MEDI-8897 is currently in a Phase IIb clinical trial in pre-term infants who are ineligible for Synagis. The safety profile is similar to that of placebo. Uses: Prevention of lower respiratory tract illness (lrti) caused by respiratory syncytial virus (rsv). Synonyms: MEDI-8897; MEDI 8897; MEDI8897. | |
| MEDICA 16 | MEDICA 16 is a selective free fatty acid 1 receptor agonist. It is also an ATP citrate lyase inhibitor. MEDICA 16 shows hypolipidemic and antidiabetogenic effects in the rat. Synonyms: MEDICA 16; MEDICA16; MEDICA-16; 3,3,14,14-Tetramethylhexadecanedioic acid. Grades: ≥98% by HPLC. CAS No. 87272-20-6. Molecular formula: C20H38O4. Mole weight: 342.51. | |
| Mefexamide hydrochloride | The hydrochloride salt form of Mefexamide which is a psychostimulant. Uses: The hydrochloride salt form of mefexamide which is a psychostimulant. Synonyms: Mefexamide, Mefesamide, Perneuron, Peroxinorm, Timodyne, ANP-297, ANP 297; ANP297; mefexadyne, mexephenamide; 2-(p-methoxyphenoxy)-n-(2-(diethylamino)ethyl)acetamide; anp297; mefaxadyne; mephexamide; mexephenamide; mp297; n-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)-acetamid; n-(2-(diethylamino)ethyl)-2-(p-methoxyphenoxy)-acetamid. Grades: 95%. CAS No. 1227-61-8. Molecular formula: C15H25ClN2O3. Mole weight: 316.82. | |
| MEG sulfate | MEG is a selective iNOS inhibitor with anti-inflammatory activity. MEG reacts with peroxynitrite with a second-order rate constant of 1900 ± 64 M-1 s-1 at 37°C. It inhibits peroxynitrite-induced oxidative damage. Synonyms: Mercaptoethylguanidine hemisulfate salt; MEG hemisulfate salt; (2-Mercaptoethyl)-guanidine sulfate. Grades: ≥98%. CAS No. 3979-00-8. Molecular formula: [C3H9N3S]2·H2SO4. Mole weight: 336.4. | |
| MEK Inhibitor | Selective dual MEK5 kinase inhibitor, with IC50 values of 4.3, 810, 1800, and >6300 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively. Synonyms: MEK inhibitor; BIX 02188; BIX02188; BIX-02188; 1H-Indole-6-carboxamide, 3-[[[3-[ (dimethylamino) methyl]phenyl]amino]phenylmethylene]-2, 3-dihydro-N-methyl-2-oxo-, (3Z)-. Grades: >98%. CAS No. 334951-92-7. Molecular formula: C26H26N4O2. Mole weight: 426.51. | |
| Melitracen hydrochloride | Melitracen hydrochloride is a potential dopamine D1/2 receptor antagonist. It has been used in combination with flupentixol in depression therapy. Synonyms: Thymeol hydrochloride; Melitracen HCl; 3-(10,10-dimethylanthracen-9-ylidene)-N,N-dimethylpropan-1-amine hydrochloride. CAS No. 10563-70-9. Molecular formula: C21H25N·HCl. Mole weight: 327.89. | |
| Melogliptin | Melogliptin is a selective dipeptidyl peptidase IV (DPP-IV) inhibitor. But No development was reported about Phase-II for Type-2 diabetes mellitus. Uses: Type 2 diabetes mellitus. Synonyms: EMD-675992; EMD 675992; EMD675992; GRC 8200; GRC8200; GRC-8200; 4-fluoro-1-[2-[[ (1R, 3S) -3- (1, 2, 4-triazol-1-ylmethyl) cyclopentyl]amino]acetyl]pyrrolidine-2-carbonitrile. Grades: 98%. CAS No. 868771-57-7. Molecular formula: C15H21FN6O. Mole weight: 320.37. | |
| MEN11467 | MEN11467, a pseudopeptide,is a new tachykinin NK1 receptor antagonist which potently antagonizes both tachykinin and antigen-mediated inflammatory responses of the respiratory tract 'in vivo' and which possesses a nanomolar affinity for guinea-pig and human tachykinin NK receptors. Synonyms: MEN11467; MEN 11467; MEN-11467; N-[(1S,2R)-2-[[(2R)-2-[methyl-[2-(4-methylphenyl)acetyl]amino]-3-naphthalen-2-ylpropanoyl]amino]cyclohexyl]-1H-indole-3-carboxamide. CAS No. 214487-46-4. Molecular formula: C38H40N4O3. Mole weight: 600.75. | |
| Mepenzolate Bromide | Mepenzolate Bromide is a muscarinic antagonist used to treat gastrointestinal disorders, and decreases the severity of elastase-induced airspace enlargement and respiratory dysfunction. Synonyms: Mepenzolate Bromide; Cantil; Gastropidil; Cantilaque; Cantilon; mepenzolate iodide; mepenzolic acid. Grades: >98%. CAS No. 76-90-4. Molecular formula: C21H26BrNO3. Mole weight: 420.34. | |
| Mephenesin | Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. Uses: An nmda receptor antagonist. Synonyms: 3-(2-methylphenoxy)propane-1,2-diol. Grades: ≥96%. CAS No. 59-47-2. Molecular formula: C10H14O3. Mole weight: 182.22. | |
| Mephenytoin | Mephenytoin is known to target sodium channel protein type 5 subunit alpha. It is a hydantoin-derivative anticonvulsant used to control various partial seizures. It may cause blood dyscrasias. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. It can be used to screen for such mutations by assaying its metabolites in urine. It is still studied largely because of its interesting hydroxylation polymorphism. It has been listed. Uses: Mephenytoin is used to control various partial seizures. it may cause blood dyscrasias. it can be used to screen for such mutations by assaying its metabolites in urine. Synonyms: 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione; Mephenytoin; Methoin; Mesantoin; Phenantoin; Methylphenetoin; Insulton. Grades: 98%. CAS No. 50-12-4. Molecular formula: C12H14N2O2. Mole weight: 218.25. | |
| Meprednisone | Meprednisone is a glucocorticoid and a methylated derivative of prednisone. Synonyms: NSC 527579; NSC527579; NSC-527579; SCH 4358; SCH4358; SCH-4358; Meprednisone; NSC-63278; NSC 63278; NSC63278; Betapar; Medrysone. Grades: >98%. CAS No. 1247-42-3. Molecular formula: C22H28O5. Mole weight: 372.455. | |
| Mercaptopurine | Mercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. Synonyms: 6-MP; 6 MP; 6MP; 6-Thiohypoxanthine; 6-thiopurine; 6-mercaptopurine. Grades: >98%. CAS No. 50-44-2. Molecular formula: C5H4N4S. Mole weight: 152.18. | |
| Merimepodib | Merimepodib is orally bioavailable IMPDH inhibitor. Synonyms: Merimepodib; VX497; VX-497; VX 497; MMP; VI21497; VI-21497; VI 21497. Grades: >98%. CAS No. 198821-22-6. Molecular formula: C23H24N4O6. Mole weight: 452.467. | |
| Mesopram | Mesopram is an orally active, selective phosphodiesterase (PDE) 4 inhibitor. In vitro, mesopram selectively inhibits the activity of type 1 helper T (Th1) cells without affecting cytokine production or proliferation of type 2 helper T (Th2) cells. It decreases the synthesis of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma). Some studies conclude that the specific type-4 phosphodiesterase inhibitor mesopram ameliorates murine colitis both in a preventive and a therapeutic setting. Synonyms: (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone. Grades: ≥98% by HPLC. CAS No. 189940-24-7. Molecular formula: C14H19NO4. Mole weight: 265.31. | |
| mesoridazine | Mesoridazine is a phenothiazine antipsychotic that binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively). Uses: Antipsychotic. Synonyms: 1-Methyl-2-[2-[2-(methylsulfinyl)phenothiazin-10-yl]ethyl]piperidine; 10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylsulfinyl)phenothiazine; Serentil; TPS 23; Thioridazine-2-sulfoxide. CAS No. 5588-33-0. Molecular formula: C21H26N2OS2. Mole weight: 386.57. | |
| Mesoridazine besylate | Mesoridazine besylate, a phenothiazine dopamine receptor anatagonist, has been described to demonstrate inhibition for D2DR and D4DR. High affinity for the cloned rat dopamine D4 receptor (Ki20 nM). Uses: Antipsychotic. Synonyms: Mesoridazine benzenesulfonate; 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine. Grades: ≥98%. CAS No. 32672-69-8. Molecular formula: C21H26N2OS2. Mole weight: 544.75. | |
| Mestranol | Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives. Uses: Estrogens. Synonyms: Mestranol; Devocin; Norquen; Ovastol; Ethynylestradiol 3-methyl ether; Ethinyl Estradiol 3 Methyl Ether; Ethinyl Estradiol 3-Methyl Ether. Grades: >98%. CAS No. 72-33-3. Molecular formula: C21H26O2. Mole weight: 310.43. | |
| Mesulergine hydrochloride | Mesulergine hydrochloride is a 5-HT2A and 2C receptor antagonist (pA2= 9.1 for each receptor). Mesulergine hydrochloride is also a D2-like dopamine receptor partial agonist and a SR-2A/SR-2C antagonist. It displays antiprolactin and antiparkinsonian effects in vivo. Uses: Antiparkinson agents. Synonyms: N'-[(8-α1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamide hydrochloride; CU-32-085. Grades: ≥99% by HPLC. CAS No. 72786-12-0. Molecular formula: C18H26N4O2S.HCl. Mole weight: 398.95. | |
| Metaproterenol hemisulfate salt | Metaproterenol hemisulfate salt is the hemisulfate salt form of Metaproterenol, which is a moderately selective beta-adrenergic agonist. It is used in the treatment of asthma and bronchospasms. It was developed by Boehringer-Ingelheim and has been withdraw from the market. Uses: Metaproterenol hemisulfate salt is used in the treatment of asthma and bronchospasms. Synonyms: Orciprenaline sulfate;Th-152; Th 152; Th152; 3-Hydroxy-5-(1-hydroxy-2-(isopropylamino)ethyl)phenyl hydrogen sulfate;5-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,3-benzenediol Sulfate;3,5-Dihydroxy-α-[(isopropylamino)methyl]benzyl Alcohol Sulfate;1-(3,5-Dihydroxyph. Grades: 95%. CAS No. 5874-97-5. Molecular formula: C11H17NO3 1/2H2O4S. Mole weight: 260.30. | |
| Methacholine chloride | Methacholine chloride, a synthetic choline ester, is pharmaceutical agent acting as a β2-adrenergic agonist used in the treatment of pulmonary and respiratory diseases including asthma. Uses: Used in the treatment of pulmonary and respiratory diseases including asthma. Synonyms: (2-Acetoxypropyl)trimethylammonium chloride; Acetyl--methylcholine chloride. Grades: ≥98%. CAS No. 62-51-1. Molecular formula: C8H18ClNO2. Mole weight: 195.69. | |
| METHDILAZINE HYDROCHLORIDE (200 MG) | This active molecular is a first-generation antihistamine and belongs to phenothiazine class. Methdilazine Hydrochloride is a Histamine H1 receptor antagonist with anticholinergic properties and can be used for the treatment of hypersensitivity reactions and pruritic skin disorders. Uses: Hypersensitivity reactions and pruritic skin disorders. Synonyms: 10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine Hydrochloride; Dilosyn; Disyncran; Methdilazine MonoHydrochloride; NSC 169091; NSC169091; NSC-169091; Tacaryl; Tacaryl Hydrochloride. Grades: 97%. CAS No. 1229-35-2. Molecular formula: C18H21ClN2S. Mole weight: 332.89. | |
| Methiothepin maleate | Methiothepin maleate. Synonyms: Methiothepin Maleate; Methiothepin Maleate salt; Metitepine; HCV-IN-281816; HCV IN 281816; HCVIN281816; 1-[10,11-Dihydro-8-(methylthio)dibenzo(Z)[b,f]thiepin-10-yl]-4-methylpiperazine maleate. Grades: ≥99% by HPLC. CAS No. 19728-88-2. Molecular formula: C20H24N2S2.C4H4O4. Mole weight: 472.62. | |
| Methoctramine tetrahydrochloride | Methoctramine is a selective M2 muscarinic acetylcholine receptor (mAChR) antagonist. Study shows that methoctramine inhibited the bradycardia induced by both vagal stimulation and ACh (ED50: 38 +/- 5 and 38 +/- 9 nmol kg-1, respectively), and facilitated vagally-induced bronchoconstriction (ED50: 58 +/- 5 nmol kg-1). At higher concentrations, methoctramine reduced responses to both nerve stimulation and exogenous ACh, indicating blockade of post-junctional muscarinic M3 receptors. Uses: Parasympatholytics. Synonyms: Methoctramine; N, N'-bis[6-[ (2-methoxyphenyl) methylamino]hexyl]octane-1, 8-diamine tetrahydrochloride. Grades: ≥95%. CAS No. 104807-46-7. Molecular formula: C36H62N4O2·4HCl. Mole weight: 728.8. | |
| Methoxamine Hydrochloride | Methoxamine Hydrochloride is an alpha-1 adrenergic agonist, similar in structure to butaxamine and 2,5-DMA. It causes prolonged peripheral vasoconstriction. It induces vasoconstriction of skin and splanchnic blood vessels, thus increasing peripheral vascular resistance and raising mean arterial blood pressure. lt is used for the treatment of paroxysmal supraventricular tachycardia and is used as a booster in the state of low blood pressure. It has been listed. Uses: Methoxamine hydrochloride is used for the treatment of paroxysmal supraventricular tachycardia and is used as a booster in the state of low blood pressure. Synonyms: 1-(2,5-Dimethoxyphenyl)-2-aminopropanol;2-Amino-1-(2,5-dimethoxyphenyl)-1-propanolhydrochloride;Alpha-(1-aminoethyl)-2,5-dimethoxy-benzenemethano hydrochloride;Methoxamine HCl;Vasoxyl hydrochloride;2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol hydrochloride. Grades: 98%. CAS No. 61-16-5. Molecular formula: C11H18ClNO3. Mole weight: 247.72. | |
| Methoxy-PEPy | Methoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist. Synonyms: methoxy-PEPy; 524924-76-3; 3-methoxy-5-(pyridin-2-ylethynyl)pyridine; MPEPy; 3-methoxy-5-pyridin-2-ylethynylpyridine; 3-methoxy-5-(2-pyridin-2-ylethynyl)pyridine; 0868W4SS6C; 3-methoxy-5-(2-pyridinylethynyl)pyridine; 3-Methoxy-5-(2-(2-pyridinyl)ethynyl)pyridine; Pyridine, 3-methoxy-5-(2-(2-pyridinyl)ethynyl)-; CHEMBL1169452; MLS003509087; UNII-0868W4SS6C; CHEMBL118498; SCHEMBL3959103; VRTFKUFTEWQHDD-UHFFFAOYSA-N; BCP16183; ZVA92476; BDBM50366854; AKOS030526834; CS-3634; NCGC00390782-01; 3-Methoxy-5-pyridin-2-ylethynyl-pyridine; HY-12510; MS-23156; SMR002157261; VU0418523-2; F85101; 3-methoxy-5-[2-(pyridin-2-yl)ethynyl]pyridine; A913545. Grades: >98%. CAS No. 524924-76-3. Molecular formula: C13H10N2O. Mole weight: 210.23. | |
| Methoxyphenamine hydrochloride | Methoxyphenamine is a β-adrenergic receptor agonist derived from amphetamine. It has been used as a bronchodilator. Uses: Adrenergic beta-agonists. Synonyms: 1-(2-methoxyphenyl)-N-methylpropan-2-amine;hydrochloride. Grades: 95 %. CAS No. 5588-10-3. Molecular formula: C11H17NO · HCl. Mole weight: 215.72. | |
| (±)-Methoxyverapamil hydrochloride | (±)-Methoxyverapamil is a phenylalkylamine L-type calcium channel blocker and methoxy derivative of verapamil. (±)-Methoxyverapamil blocks recombinant rat L-type calcium channels expressed in tsA201 cells with IC50 values of 782 and 8,000 nM at holding potentials of 10 and -60 mV, respectively. Uses: Calcium channel blockers. Synonyms: Gallopamil; NSC 274966; 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride. Grades: ≥98%. CAS No. 16662-46-7. Molecular formula: C28H40N2O5·HCl. Mole weight: 521.09. | |
| Methoxy-X04 | Methoxy-X04, also called CHEMBL2181036, as a fluorescent Amyloid-β (Aβ) probe, can be easily synthesized with carbon-11 (11C), and can detect and quantify plaques, tangles and cerebrovascular amyloid. Synonyms: Methoxy-X04; Methoxy X04; MethoxyX04; 4-[(E)-2-[4-[(E)-2-(4-hydroxyphenyl)ethenyl]-3-methoxyphenyl]ethenyl]phenol; 1,4-bis(4'-hydroxystyryl)-2-methoxybenzene; methoxy-X04; CHEMBL2181036; 863918-78-9; Methoxy-04; Methoxy-X04; SCHEMBL13191839; AOB1745; SYN5201; C23H20O3; BDBM50398211; ZINC34946459; AKOS024458419; 4,4'-(2-Methoxy-1,4-phenylenebisvinylene)bisphenol; Methoxy-X04|4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol. CAS No. 863918-78-9. Molecular formula: C23H20O3. Mole weight: 344.4. | |
| METHSUXIMIDE | Mesuximide is a succinimide anticonvulsant medication. The therapeutic efficacy of methosuximide is due to its pharmacologically active metabolite, N-desmethylmethosuximide. This active metabolite has a longer half-life and attains much higher plasma levels than its parent. Uses: Anticonvulsant. Synonyms: 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine;1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione;1,3-dimethyl-3-phenyl-5-pyrrolidinedione;1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione;1,3-dimethyl-3-phenylsuccinimide;2,5-Pyrrolidinedione, 1,3-dimethyl-3-phenyl-;alpha-. Grades: 98%. CAS No. 77-41-8. Molecular formula: C12H13NO2. Mole weight: 203.24. | |
| Methyl α-Linolenyl Fluorophosphonate | Methyl α-linolenyl fluorophosphonate (MLnFP) is an analog of methyl arachidonyl fluorophosphonate (MAFP), an inhibitor of PLA2, FAAH and CB1 receptor. Synonyms: MαLnFP; Methyl alpha-Linolenyl Fluorophosphonate; (3Z,6Z,9Z)-18-[fluoro(methoxy)phosphoryl]octadeca-3,6,9-triene. Grades: ≥98%. Molecular formula: C19H34FO2P. Mole weight: 344.4. | |
| Methyl Arachidonyl Fluorophosphonate | Methyl arachidonyl fluorophosphonate (MAFP) is a selective and irreversible inhibitor of PLA2 and FAAH. It also binds to CB1 receptor in rat brain membrane preparations. Uses: Enzyme inhibitors. Synonyms: MAFP; (5Z,8Z,11Z,14Z)-1-[fluoro(methoxy)phosphoryl]icosa-5,8,11,14-tetraene. Grades: ≥98%. CAS No. 188404-10-6. Molecular formula: C21H36FO2P. Mole weight: 370.5. | |
| Methylbenactyzine bromide | Methylbenactyzine bromide is a muscarinic acetylcholine receptor (mAChR) antagonist. It has been used as a spasmolytic for the treatment of gastrointestinal spasm. Synonyms: Gastrimade; Noinarin; Paragone; Semulgin; Diethyl-[2-(2-hydroxy-2,2-diphenylacetyl)oxyethyl]-methylazanium bromide. CAS No. 3166-62-9. Molecular formula: C21H28BrNO3. Mole weight: 422.36. | |
| Methylcarbamyl PAF C-16 | Methylcarbamyl PAF C-16 is an analog of PAF C-16 that acts as a PAF-R activator. Methylcarbamyl PAF C-16 binds to PAF-R, leading to activation of platelet aggregation and inhibition of Mycobacterium bovis BCG (M. bovis BCG) and Mycobacterium smegmatis (M. smegmatis) growth. Synonyms: C-PAF; Carbamyl-PAF; 1-O-Hexadecyl-2-N-methylcarbamyl-SN-glycero-3-phosphocholine; [(2R)-3-hexadecoxy-2-(methylcarbamoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate. Grades: ≥98%. CAS No. 91575-58-5. Molecular formula: C26H55N2O7P. Mole weight: 538.7. | |
| Methyldopate | Methyldopate is an antihypertensive medication for the treatment of hypertension. It is the ethyl ester prodrug of methyldopa, an α2-adrenergic agonist stimulating central α2-adrenergic receptors and decreasing sympathetic outflow as well as blood pressure. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: α-Methyldopa ethyl ester; Ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate. Grades: ≥95%. CAS No. 6014-30-8. Molecular formula: C12H17NO4. Mole weight: 239.3. | |
| Methyl γ-Linolenyl Fluorophosphonate | Methyl γ-Linolenyl Fluorophosphonate (MLnFP) is an analog of methyl arachidonyl fluorophosphonate (MAFP), an inhibitor of PLA2, FAAH and CB1 receptor. Synonyms: MγLnFP; Methyl gamma-Linolenyl Fluorophosphonate; (6Z,9Z,12Z)-1-[fluoro(methoxy)phosphoryl]octadeca-6,9,12-triene. Grades: ≥98%. CAS No. 1370451-91-4. Molecular formula: C19H34FO2P. Mole weight: 344.4. | |
| Methyl-L-NIO hydrochloride | Nitric oxide synthase (NOS) catalyzes the conversion of L-arginine to nitric oxide (NO) and citrulline. Methyl-L-NIO is a competitive inhibitor of nitric oxide synthase (NOS) that blocks L-arginine converting to NO and citrulline. Synonyms: (2S)-2-Amino-5-(1-aminopropylideneamino)pentanoic acid hydrochloride. Grades: ≥98%. CAS No. 150403-96-6. Molecular formula: C8H17N3O2·HCl. Mole weight: 223.7. | |
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