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| Product | Description | |
|---|---|---|
| LaniceMine | Lanicemine, also know as AZD6765, has been to be a NMDA receptor antagonist that was once studiedd as a neuroprotective agent which was discontinued in 2007 and it was redeveloped to be an potential antidepressant agent a few year later. Synonyms: Lanicemine(free base); Lanicemine(2HCl) ARL-15896; ARL-15896AR; ARR-15896; ARR-15896AR; FPL-15896; FPL-15896AR ARL15896; ARL15896AR; ARR15896; ARR15896AR; FPL15896; FPL15896AR ARL 15896; ARL 15896AR; ARR 15896; ARR 15896AR; FPL 15896; FPL 15896AR; (1S)-1-phenyl-2-pyridin-2-ylethanamine. Grades: 98%. CAS No. 153322-05-5. Molecular formula: C13H14N2. Mole weight: 198.27. |  |
| L-AP4 | L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus. L-AP4 is a synaptic depressant. Synonyms: L-(+)-2-Amino-4-phosphonobutyric acid; (2S)-2-amino-4-phosphonobutanoic acid; L-AP4; L AP4; LAP4. Grades: ≥99% by HPLC. CAS No. 23052-81-5. Molecular formula: C4H10NO5P. Mole weight: 183.1. | |
| L-AP5 | L-AP5 has been found to be an NMDA antagonist as well as a quisqualate-sensitized AP6 site agonist. Synonyms: L-(+)-2-Amino-5-phosphonopentanoic acid. Grades: ≥99% by HPLC. CAS No. 79055-67-7. Molecular formula: C5H12NO5P. Mole weight: 197.13. | |
| Lascufloxacin | Lascufloxacin is an antibacterial drug candidate. Phase-III clinical trials in Respiratory tract infections and in Community-acquired pneumonia in Japan were on-going. Uses: Community-acquired pneumonia; otorhinolaryngological infections; respiratory tract infections. Synonyms: KRP-AM1977; 7-{(3S,4S)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin- 1-yl}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo- 1,4-dihydroquinoline-3-carboxylic acid. Grades: 98%. CAS No. 848416-07-9. Molecular formula: C21H24F3N3O4. Mole weight: 439.43. | |
| Latamoxef sodium | Latamoxef sodium, a broad- spectrum beta-lactam antibiotic, inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria, it is ineffective against methicillin-resistant S. aureus and Enterococci. Uses: An oxacephem antibiotic. moxalactam sodium is more effective against escherichia coli and pseudomonas aeruginosa than cephalosporins. Synonyms: Moxalactam sodium; disodium;7-[[2-carboxylato-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: 98%. CAS No. 64953-12-4. Molecular formula: C20H18N6Na2O9S. Mole weight: 564.44. | |
| LAU159 | LAU159 is a selective antagonist of α6β3γ2 GABAA receptor. Synonyms: 8-chloro-2-(3-methoxyphenyl)-1H-pyrazolo[4,3-c]quinolin-3-one. CAS No. 2055050-87-6. Molecular formula: C17H12ClN3O2. Mole weight: 325.8. | |
| Lavendustin C | Lavendustin C, also known as HDBA and NSC 666251, inhibits Ca2+/CaMKII (calmodulin kinase II) (IC50=0.2 μM), EGFR tyrosine kinase (IC50=44 nM) and SRC (IC50=0.5 μM). At a concentration of 10-150 μM, Lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation. Synonyms: 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid; Lavendustin C; HDBA, NSC 666251. NSC666251. NSC-666251. CAS No. 125697-93-0. Molecular formula: C14H13NO5. Mole weight: 275.26. | |
| Lazabemide hydrate | Lazabemide, a pyridine derivative, is a reversible and selective monoamine oxidase B inhibitor that has probable effect for Parkinson's disease. IC50: 30 nM. It could also influence the absorption of some monoamines like noradrenalin, serotonin and dopami. Uses: Lazabemide is a reversible and selective monoamine oxidase b inhibitor that has probable effect against parkinson's disease. Synonyms: Lazabemide; Cardaptive; MK-0524; MK 0524; MK0524; Laropiprant; N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate, Ro 19-6327 hydrate. Grades: 95%. CAS No. 103878-84-8. Molecular formula: C8H10ClN3O. Mole weight: 199.64 (anhydrous basis). | |
| Lazertinib | Lazertinib, also known as YH-25448 and GNS-1480, is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible 3rd generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer. Lazertinib is expected to beneficial for the NSCLC patients with brain metastasis due to good blood brain barrier (BBB) penetration property as well as for the treatment of primary lung lesion and extracranial lesions. Uses: Protein kinase inhibitors. Synonyms: 2-Propenamide, N-(5-((4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)-2-pyrimidinyl)amino)-4-methoxy-2-(4-morpholinyl)phenyl)-; N-(5-((4-(4-((Dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl)amino)-4-methoxy-2-morpholinophenyl)acrylamide; Lazertinib; YH-25448; YH 25448; YH25448; GNS-1480; GNS 1480; GNS1480. CAS No. 1903008-80-9. Molecular formula: C30H34N8O3. Mole weight: 554.64. | |
| LBX192 | LBX192 is a Liver Targeted Glucokinase Activator. It can activate the GK enzyme in vitro at low nM concentrations and reduce glucose levels during an oral glucose tolerance test in normal as well as diabetic mice. Synonyms: LBX192; LBX 192; LBX-192; NVP-LBX192; NVP-LBX-192; NVP-LBX 192; (R)-3-cyclopentyl-N-(5-methoxythiazolo[5,4-b]pyridin-2-yl)-2-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)propanamide. Grades: 98%. CAS No. 866772-52-3. Molecular formula: C26H33N5O4S2. Mole weight: 543.70. | |
| L-Canavanine sulfate | The sulfate salt form of L-Canavanine, a homoserine analog, has been found to be a NO synthase inhibitor. Synonyms: L-2-Amino-4-(guanidiooxy)butyric acid sulfate. Grades: ≥95% by HPLC. CAS No. 2219-31-0. Molecular formula: C5H12N4O3.H2SO4. Mole weight: 274.25. | |
| LCB 03-0110 dihydrochloride | LCB 03-0110 dihydrochloride is a c-Src kinase inhibitor with IC50 value of 1.3 nM. It can inhibit activation of macrophages and fibroblasts and suppress scar formation in a wound healing model. Synonyms: LCB 03-0110 dihydrochloride; LCB 03-0110 (dihydrochloride); 3-((2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-yl)amino)phenol dihydrochloride; 1962928-28-4; AKOS027470220; HY-110367; CS-0033305; 3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride; 3-[[2-[3-(morpholin-4-ylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol; dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1962928-28-4. Molecular formula: C24H25Cl2N3O2S. Mole weight: 490.4. | |
| L-CCG-l | L-CCG-l is a potent group II metabotropic glutamate receptor (mGluR) agonist. Uses: Excitatory amino acid agonists. Synonyms: (2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine; (1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 117857-93-9. Molecular formula: C6H9NO4. Mole weight: 159.14. | |
| L-CCG-lll | L-CCG-lll is a potent and competitive inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate. Synonyms: (2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine; (1R,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid. CAS No. 117857-95-1. Molecular formula: C6H9NO4. Mole weight: 159.14. | |
| LCH7749944 HCl | LCH7749944 HCl is a novel and potent PAK4 inhibitor. It could effectively suppress the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway. It significantly inhibited the migration and invasion of human gastric cancer cells in conjunction with concomitant blockage of PAK4/LIMK1/cofilin and PAK4/MEK-1/ERK1/2/MMP2 pathways. It also inhibited the formation of filopodia and induced cell elongation in SGC7901 cells. It caused successful inhibition of EGFR activity due to its inhibitory effect on PAK4. It may be potential therapeutic strategies for gastric cancer. Uses: Lch7749944 hcl may be potential therapeutic strategies for gastric cancer. Synonyms: LCH-7749944 HCl; LCH 7749944 HCl; LCH7749944 HCl; N2-(3-methoxyphenyl)-N4-((tetrahydrofuran-2-yl)methyl)quinazoline-2,4-diamine HCl. Grades: >98 %. CAS No. 1049788-58-0. Molecular formula: C20H23N4O2Cl. Mole weight: 386.87. | |
| L-Chicoric acid | Cichoric acid, that can be isolated from the herbs of Echinacea purpurea, has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. Chicoric acid may reduce acute alcohol-induced steatosis in mice through interfering with the induction of iNOS and iNOS-dependent signaling cascades in the liver. Chicoric acid also inhibited cell viability and induced apoptosis in 3T3-L1 preadipocytes which was characterized by chromatin condensation and poly ADP-ribose-polymerase (PARP) cleavage. Uses: Anti-inflammatory. Synonyms: (2r,3r)-2,3-bis[[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]butanedioic acid; (2R,3R)-2,3-BIS[[(2E)-3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL]OXY]-BUTANE DIOIC ACID; CHICHORIC ACID; CICHORIC ACID; CICHORINIC ACID; DICAFFEOYL TARTARIC ACID; L-CHICORIC ACID; Cichoric Acid (Chicoric acid). Grades: >98%. CAS No. 70831-56-0. Molecular formula: C22H18O12. Mole weight: 474.37. | |
| Lck Inhibitor | Lck Inhibitor is a small-molecule inhibitor. It takes participate in the T-cell receptor (TCR) signal transduction and affects the expression of genes associated with cell proliferation, cytokine release and T-cell survival. It has been designed and developed as therapeutic agents for the treatment for T-cell-mediated autoimmune and organ transplant rejection. It showed high selectivity against Lck over another Src family kinase Src and the kinases. It also showed more than 1000-fold greater selectivity over CDK, MAPK and the RSK family. Synonyms: TC-S 7003; TC S 7003; TCS 7003; TC-S-7003; TCS7003; TCS-7003. Grades: >98%. CAS No. 847950-09-8. Molecular formula: C31H30N8O. Mole weight: 530.62. | |
| Lck inhibitor 2 | Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. It inhibited 48 kinases with control less than 1%(33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel). Synonyms: Benzamide, 3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]-. Grades: >98%. CAS No. 944795-06-6. Molecular formula: C18H17N5O2. Mole weight: 335.36. | |
| LCQ-908 | LCQ-908 is a new generation of diacylglycerol acyltransferase 1 (DGAT1) inhibitor as anti-obesity and anti-diabetic agents. It is now in phase II clinical trials. Synonyms: Pradigastat; LCQ-908; LCQ 908; LCQ908. Grades: >98%. CAS No. 956136-95-1. Molecular formula: C25H24F3N3O2. Mole weight: 455.47. | |
| LCRF-0004 | This active molecular is a selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been reported that it usually overexpressed in the pancreatic cancer. Preclinical research shows that inhibition of RON function can decrease pancreatic cancer cell migration, invasion and survival and this can also sensitize pancreatic cancer cells to chemotherapy. RON receptor tyrosine kinase may become a potential therapeutic target for the pancreatic cancer. Uses: Pancreatic cancer. Synonyms: LCRF-0004; LCRF 0004; LCRF0004; N-(3-fluoro-4-((2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide. Grades: 98%. CAS No. 1229611-73-7. Molecular formula: C28H18F4N6O2S. Mole weight: 578.55. | |
| L-Cysteinesulfinic acid | L-Cysteinesulfinic acid is an agonist of mGlu1a and mGlu5a subtypes expressed in clonal RGT cell lines and an agonist of NMDA. It is used to probe conformational flexibility of human DJ-1, which is very important in protecting against oxidative stress and other factors contributing to Parkinson's. It is putative excitatory amino acid neurotransmitter. Synonyms: 3-Sulfino-L-alanine; Cysteinesulfinic Acid; L-2-Amino-3-sulfinopropionic Acid. CAS No. 1115-65-7. Molecular formula: C3H7NO4S. Mole weight: 153.15. | |
| LCZ696 | LCZ696 is a potent ARNi inhibitor and an investigational drug to treat heart failure. Chemically, LCZ696 is a mixture of valsartan and sacubitril in a 1:1 molar ratio. Synonyms: LCZ696; LCZ-696; LCZ 696. valsartan / sacubitril (1:1). Brand name: Entresto. Grades: >98%. CAS No. 936623-90-4. Molecular formula: C96H120N12Na6O21. Mole weight: 1916.02. | |
| LDC000067 | LDC000067 is a highly selective CDK9 inhibitor with IC50 of 44 nM, 55/125/210/ >227/ >227-fold selectivity over CDK2/1/4/6/7.LDC000067 reduces Ser2-P, induces p53 activation and leads to apoptosis in mESCs. Synonyms: LDC067; LDC 067; LDC-067; LDC000067; LDC-000067; LDC 000067. Grades: >98%. CAS No. 1073485-20-7. Molecular formula: C18H18N4O3S. Mole weight: 370.43. | |
| LDC4297 | LDC4297 is a potent and selective cyclin-dependent protein kinase 7 (CDK7) inhibitor with an IC50 of 0.13 nM. Synonyms: 2-piperidin-3-yloxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine; LDC4297; LDC-4297; LDC 4297; LCD044297; LCD-044297; LCD 044297. Grades: 98.25%. CAS No. 1453834-21-3. Molecular formula: C23H28N8O. Mole weight: 432.52. | |
| LDK378 dihydrochloride | Ceritinib, also known as LDK378, is a selective inhibitor of ALK1, a target found in metastatic non-small cell lung cancer (NSCLC). In Phase I trials, LDK378 showed a marked clinical response in 78 patients with anaplastic lymphoma kinase positive (ALK+) metastatic non-small cell lung cancer (NSCLC) who had progressed during or after crizotinib therapy or had not been previously treated with crizotinib. LDK378 blocks the ALK protein and stops it sending growth signals to cancer cells, which may stop them growing. Synonyms: LDK 378 dihydrochloride; LDK-378 dihydrochloride; LDK378 dihydrochloride; Ceritinib dihydrochloride. Grades: >98%. CAS No. 1380575-43-8. Molecular formula: C28H38Cl3N5O3S. Mole weight: 631.06. | |
| LDN 193189 dihydrochloride | LDN 193189 dihydrochloride is a selective ALK2 and ALK3 inhibitor with IC50 values of 5 and 30 nM. It can inhibit FOP and ectopic ossification. LDN 193189 is a potential agent in the treatment of NSCLC lung tumors. Synonyms: LDN 193189 dihydrochloride; LDN193189 dihydrochloride; LDN-193189 dihydrochloride; 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1435934-00-1. Molecular formula: C25H22N6.2HCl. Mole weight: 479.4. | |
| LDN-211904 oxalate | LDN-211904 is an inhibitor of erythropoietin-producing hepatocellular carcinoma (Eph) receptors. It was profiled for inhibitory activity against a panel of 288 kinases and found to be quite selective for tyrosine kinases. Synonyms: LDN-211904; LDN 211904 oxalate; LDN211904 oxalate; N-(2-chlorophenyl)-6-piperidin-4-ylimidazo[1,2-a]pyridine-3-carboxamide oxalate. Grades: ≥98%. CAS No. 1198408-78-4. Molecular formula: C19H19ClN4O·C2H2O4. Mole weight: 444.9. | |
| LDN 212854 trihydrochloride | LDN 212854 trihydrochloride is a hydrochloride salt form of LDN 212854, which is a potent ALK2-biased BMP type I receptor kinase inhibitor (IC50 values 2.4 nM, 1.3 nM, and 85.8 nM for ALK1, 2, and 3 resp.). Study shows that LDN-212854 potently inhibits heterotopic ossification in an inducible transgenic mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Synonyms: LDN 212854 trihydrochloride; LDN212854 trihydrochloride; LDN-212854 trihydrochloride; 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline trihydrochloride. Grades: 99%. Molecular formula: C25H22N6.3HCl. Mole weight: 515.87. | |
| LDN-57444 | LDN-57444 is a reversible, competitive proteasome inhibitor for UCH-L1 with IC50 of 0.88 μM, 28-fold greater selectivity over isoform UCH-L3. Synonyms: ARO 002; ARO002; ARO-002; LDN-57444; LDN 57444; LDN57444. Grades: >98%. CAS No. 668467-91-2. Molecular formula: C17H11Cl3N2O3. Mole weight: 397.64. | |
| LDV FITC | LDV FITC is a fluorescent ligand. It can bind to the α4β1 integrin (VLA-4) with high affinity. It can be used to detect VLA-4 affinity and conformational changes. Synonyms: LDV FITC; 1207610-07-8; 4- [ [ (5S) -5-Carboxy-5- [ [ (2S) -2- [ [ (2S) -2- [ [ (2S) -1- [ (2S) -2- [ [ (2S) -3-carboxy-2- [ [ (2S) -4-methyl-2- [ [2- [4- [ (2-methylphenyl) carbamoylamino] phenyl] acetyl] amino] pentanoyl] amino] propanoyl] amino] -3-methylbutanoyl] pyrrolidine-2-carbonyl] amino] propanoyl] amino] propanoyl] amino] pentyl] carbamothioylamino] -2- (3-hydroxy-6-oxoxanthen-9-yl) benzoic acid; AKOS025147314; PD079718. Grades: ≥98% by HPLC. CAS No. 1207610-07-8. Molecular formula: C69H81N11O17S. Mole weight: 1368.54. | |
| LE 300 | LE 300 is a selective dopamine D1 receptor antagonist. It also displays moderate affinity for the 5-HT2A receptor. Synonyms: LE 300; LE300; LE-300; 6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f][3]benzazecine. Grades: ≥98% by HPLC. CAS No. 274694-98-3. Molecular formula: C20H22N2. Mole weight: 290.41. | |
| LED209 | LED209 is a highly selective for histidine sensor kinase QseC that blocks both norepinephrine- and epinephrine-triggered QseC-dependent virulence gene expression at 5 pM in vitro. Synonyms: 1-phenyl-3-[4-(phenylsulfamoyl)phenyl]thioureaLED 209; LED-209; LED209245342-14-7HNDRSTUKPCLQLT-UHFFFAOYSA-NN-Phenyl-4- (3-phenylthioureido) Benzene sulfonamide N-phenyl-4- [ [ (phenylamino) thioxo methyl ] amino] Benzene sulfonamide AC1MQ46PCHEMBL516533SCHEMBL3396831. CAS No. 245342-14-7. Molecular formula: C19H17N3O2S2. Mole weight: 383.48. | |
| Ledipasvir diacetone | Against JFH1/3a-NS5A, DCV was more potent (EC(50) = 0.52 nM) than GS-5885 (EC(50) = 141 nM). DCV sensitivity was increased against JFH1/3a-NS5A-M28V (EC50 = 0.006 nM), A30V (EC(50) = 0.012 nM), and E92A (EC(50) = 0.004 nM) while the NS5A-A30K and -Y93H variants exhibited reduced sensitivity to DCV (EC50 values of 23 nM and 1120 nM, respectively) and to GS-5885 (EC50 values of 1770 nM and 4300 nM, respectively). GS-5885 was well tolerated and resulted in median maximal reductions in HCV RNA ranging from 2.3 log(10) IU/ml (1 mg QD) to 3.3 log(10) IU/ml (10 mg QD in genotype 1b and 30 mg QD). E(max) modeling indicated GS-5885 30 mg was associated with>95% of maximal antiviral response to HCV genotype 1a. HCV RNA reductions were generally more sustained among patients with genotype 1b vs. 1a. Three of 60 patients had a reduced response and harbored NS5A-resistant virus at baseline. NS5A sequencing identified residues 30 and 31 in genotype 1a, and 93 in genotype 1b as the predominant sites of mutation following GS-5885 dosing. Plasma pharmacokinetics was consistent with QD dosing. Synonyms: GS-5885 diacetone; GS 5885 diacetone; GS5885 diacetone. Grades: >98%. CAS No. 1502655-48-2. Molecular formula: C55H66F2N8O8. Mole weight: 1005.16. | |
| Ledipasvir D-tartrate | Against JFH1/3a-NS5A, DCV was more potent (EC(50) = 0.52 nM) than GS-5885 (EC(50) = 141 nM). DCV sensitivity was increased against JFH1/3a-NS5A-M28V (EC50 = 0.006 nM), A30V (EC(50) = 0.012 nM), and E92A (EC(50) = 0.004 nM) while the NS5A-A30K and -Y93H variants exhibited reduced sensitivity to DCV (EC50 values of 23 nM and 1120 nM, respectively) and to GS-5885 (EC50 values of 1770 nM and 4300 nM, respectively). GS-5885 was well tolerated and resulted in median maximal reductions in HCV RNA ranging from 2.3 log(10) IU/ml (1 mg QD) to 3.3 log(10) IU/ml (10 mg QD in genotype 1b and 30 mg QD). E(max) modeling indicated GS-5885 30 mg was associated with>95% of maximal antiviral response to HCV genotype 1a. HCV RNA reductions were generally more sustained among patients with genotype 1b vs. 1a. Three of 60 patients had a reduced response and harbored NS5A-resistant virus at baseline. NS5A sequencing identified residues 30 and 31 in genotype 1a, and 93 in genotype 1b as the predominant sites of mutation following GS-5885 dosing. Plasma pharmacokinetics was consistent with QD dosing. Synonyms: GS-5885 D-tartrate; GS 5885 D-tartrate; GS5885 D-tartrate. Grades: >98%. CAS No. 1502654-87-6. Molecular formula: C53H60F2N8O12. Mole weight: 1039.09. | |
| LEE011 hydrochloride | CDK4/6 inhibitor LEE011 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.Treatment with LEE011 significantly reduced proliferation in 12 of 17 human neuroblastoma-derived cell lines by inducing cytostasis at nanomolar concentrations (mean IC50=307 ± 68 nmol/L in sensitive lines). LEE011 caused cell-cycle arrest and cellular senescence that was attributed to dose-dependent decreases in phosphorylated RB and FOXM1, respectively. Responsiveness of neuroblastoma xenografts to LEE011 translated to the in vivo setting in that there was a direct correlation of in vitro IC50 values with degree of subcutaneous xenograft growth delay. Synonyms: 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride; Ribociclib hydrochloride; LEE011; LEE-011 LEE 011. Grades: >98%. CAS No. 1211443-80-9. Molecular formula: C23H31ClN8O. Mole weight: 471.0. | |
| LEE011 succinate hydrate | LEE011 succinate hydrate is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. Synonyms: Ribociclib succinate hydrate; LEE 011 succinate hydrate; LEE-011 succinate hydrate. Grades: >98%. CAS No. 1374639-79-8. Molecular formula: C27H38N8O6X. Mole weight: 570.64. | |
| Leelamine | Leelamine, a diterpene molecule, has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Leelamine is also a PDK(pyruvate dehydrogenase kinase inhibitor). Synonyms: [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine; dehydroabietylamine; DEHYDROABIETYLAMINE; (+)-Dehydroabietylamine; Dehydroabiethylamine; 16496-99-4 Leelamine (hydrochloride). Grades: ≥90%. CAS No. 1446-61-3. Molecular formula: C20H31N. Mole weight: 285.5. | |
| Leelamine hydrochloride | Leelamine is a diterpene amine exhibiting low affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It also acts as an inhibitor of pyruvate dehydrogenase kinase (PDK). Leelamine inhibits intracellular cholesterol transport and suppresses cancer cell growth. Synonyms: Lylamine hydrochloride; Dehydroabiethylamine hydrochloride; [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine hydrochloride. Grades: ≥98%. CAS No. 16496-99-4. Molecular formula: C20H31N·HCl. Mole weight: 321.9. | |
| LEI-101 hydrochloride | LEI-101 hydrochloride is a potent, selective and orally bioavailable cannabinoid CB2 receptor agonist with a pEC50 of 8 for hCB2, and a pKi of less than 4 for hERG. LEI-101 is about 100-fold more potent in binding to CB2 receptors than CB1 receptors. Synonyms: 3-Cyclopropyl-1-(4-{6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl}benzyl)-2,4-imidazolidinedione hydrochloride (1:1); 2,4-Imidazolidinedione, 3-cyclopropyl-1-[[4-[6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl]phenyl]methyl]-, hydrochloride (1:1). Grades: ≥98%. CAS No. 2250025-91-1. Molecular formula: C23H26ClFN4O4S. Mole weight: 508.99. | |
| Lei-Dab 7 | HLei-Dab 7 is a calcium-activated potassium channel blocker. Synonyms: L-alanyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-leucyl-L-arginyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-glutaminyl-L-leucyl-L-seryl-L-cysteinyl-L-arginyl-L-seryl-L-leucylglycyl-L-leucyl-L-leucylglycyl-L-lysyl-L-cysteinyl-L-isoleucylglycyl-L-α-aspartyl-L-lysyl-L-cysteinyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-lysyl-L-Histidinamide-cyclic (3?21)-(8?26)-(12?28)-tris(disulfide). Grades: ≥97%. CAS No. 1061556-49-7. Molecular formula: C141H236N46O39S6. Mole weight: 3392.06. | |
| Leniolisib | Leniolisib is a PI3K (phosphatidylinositol 3-kinase) inhibitor. No detailed information has been published yet. Synonyms: (S)-1-(3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one;UNII-L22772Z9CP. Grades: 98%. CAS No. 1354690-24-6. Molecular formula: C21H25F3N6O2. Mole weight: 450.46. | |
| Lensiprazine | Lensiprazine is a potent in vitro dopamine receptor antagonist and highly active as serotonin reuptake inhibitor. Uses: D(2) receptor antagonist. Synonyms: SLV-314; SLV 314; SLV314; (2R)-8-[4-[3-(5-Fluoro-1H-indol-3-yl)propyl]-1-piperazinyl]-2-methyl-2H-1,4-benzoxazin-3(4H)-one. Grades: ≥98%. CAS No. 327026-93-7. Molecular formula: C24H27FN4O2. Mole weight: 422.50. | |
| LEO29102 | LEO29102 is a potent, selective, and soft-drug phosphodiesterase 4 (PDE4) inhibitor. It shows properties suitable for patient-friendly formulations giving efficient drug delivery to the skin. It may be useful for treatment of dermatological diseases and atopic dermatitis. It was developed by Neochem Pharmaceutical and in clinic phase 2 trials. Uses: Leo29102 may be useful for treatment of dermatological diseases and atopic dermatitis. Synonyms: LEO-29102; LEO 29102; LEO29102. 2-(6-(2-(3,5-dichloropyridin-4-yl)acetyl)-2,3-dimethoxyphenoxy)-N-propylacetamide. Grades: >98 %. CAS No. 1035572-38-3. Molecular formula: C20H22Cl2N2O5. Mole weight: 441.31. | |
| Lerimazoline | Lerimazoline is an α-adrenergic receptor agonist. It inhibits secretion of nasal mucus. It causes hypertension. It is common used in the form of hydrochloride. Uses: Lerimazoline inhibits secretion of nasal mucus. it causes hypertension. Synonyms: 4,5-Dihydro-2-[(2,4,6-trimethylphenyl)methyl]-1H-imidazole;Trimazoline;2-[(2,4,6-Trimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;ST-71; ST71; ST 71; Trimazoline; Trimizoline; Lerimazoline. Grades: 98%. CAS No. 54765-26-3. Molecular formula: C13H18N2. Mole weight: 202.30. | |
| Lerociclib | Lerociclib is a novel, selective, and orally bioavailable CDK4/6 inhibitor with biochemical IC50 values of 1 nM, 2 nM and 28 μnM for CDK4, CDK6 and CDK9 respectively. Synonyms: G1T38. CAS No. 1628256-23-4. Molecular formula: C26H34N8O. Mole weight: 474.60. | |
| Lersivirine | Lersivirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for the treatment of HIV-1 infection. It prevents HIV from entering the nucleus of healthy CD4 cells, which prevents the cells from producing new virus and decreases the amount of virus in the body. Synonyms: UK-453061; UK453061; UK 453061; UK-453,061; UK453,061; UK 453,061;Lersivirine. Grades: >98%. CAS No. 473921-12-9. Molecular formula: C17H18N4O2. Mole weight: 310.35. | |
| L-erythro Sphingosine | L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1). It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%). Synonyms: L-erythro-C18-Sphingosine; (E,2R,3S)-2-aminooctadec-4-ene-1,3-diol. Grades: ≥98%. CAS No. 6036-75-5. Molecular formula: C18H37NO2. Mole weight: 299.49. | |
| Lesinurad sodium | Lesinurad sodium is an once-daily inhibitor of URAT1, which is a transporter in the kidney that regulates uric acid excretion from the body. Synonyms: sodium 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate; sodium Lesinurad; RDEA594 sodium; RDEA 594 sodium; RDEA-594 sodium; Zurampic sodium; Acetic acid, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, sodium salt (1:1). Grades: >98%. CAS No. 1151516-14-1. Molecular formula: C17H13BrN3NaO2S. Mole weight: 426.26. | |
| Lesogaberan | Lesogaberan is a potent and selective GABAB receptor agonist that limit the clinical use of baclofen for the treatment of GERD. Uses: Gaba b receptor agonists. Synonyms: AZD-3355; AZD 3355; AZD3355; Lesogaberan.[(2R)-3-amino-2-fluoropropyl]-hydroxy-oxophosphanium. Grades: ≥98%. CAS No. 344413-67-8. Molecular formula: C3H9FNO2P. Mole weight: 141.03. | |
| [Leu31,Pro34]-Neuropeptide Y (human, rat) | [Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Synonyms: [Leu31,Pro34]-NPY (human, rat); H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2; L-tyrosyl-L-prolyl-L-seryl-L-lysyl-L-prolyl-L-alpha-aspartyl-L-asparagyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-leucyl-L-threonyl-L-arginyl-L-prolyl-L-arginyl-L-tyrosinamide. Grades: ≥95%. CAS No. 132699-73-1. Molecular formula: C189H284N54O56S. Mole weight: 4240.67. | |
| [Leu31,Pro34] Neuropeptide Y (human) trifluoroacetate salt | [Leu31,Pro34] Neuropeptide Y (NPY) is an agonist of the NPY receptors Y1 and Y5. Synonyms: [Leu31,Pro34] NPY; [Leu31,Pro34]-NPY (human). Grades: ≥95%. Molecular formula: C189H284N54O56S·xCF3COOH. Mole weight: 4240.67. | |
| [Leu31,Pro34]-Neuropeptide Y (porcine) | [Leu31,Pro34]-Neuropeptide Y (porcine) is a high affinity neuropeptide Y Y1 receptor agonist (Ki = 0.54 nM). Synonyms: (Leu(31),pro(34))npy; 31-Leu-34-pro-neuropeptide Y; Pancreatic polypeptide (chicken), 1-L-tyrosine-4-L-lysine-6-L-aspartic acid-7-L-asparagine-10-L-glutamic acid-14-L-alanine-18-L-alanine-20-L-tyrosine-22-L-serine-23-L-alanine-25-L-arginine-26-L-histidine-28-L-isoleucine-30-L-leucine-31-L-leucine-34-L-proline. CAS No. 125580-28-1. Molecular formula: C190H286N54O56. Mole weight: 4222.63. | |
| Leucovorin calcium pentahydrate | Leucovorin is a derivative of folic acid, which can be used to increase levels of folic acid under conditions favoring folic acid inhibition. Synonyms: Folinic acid. Grades: >98%. CAS No. 6035-45-6. Molecular formula: C21H25CaN7O7.5H2O. Mole weight: 601.58. | |
| Leucylarginylproline | Leucylarginylproline, also called as H-Leu-Arg-Pro-OH, is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.27μM). Synonyms: H-Leu-Arg-Pro-OH; L-leucyl-L-arginyl-L-proline; (2S)-1-[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-5 (diaminomethylideneamino) pentanoyl]pyrrolidine-2-carboxylic acid. CAS No. 133943-59-6. Molecular formula: C17H32N6O4. Mole weight: 384.47. | |
| Leukadherin-1 | Leukadherin-1, also known as LA1, is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1. Leukadherin-1 suppresses human innate inflammatory signalling. leukadherin-1 increases CD11b/CD18-dependent adhesion via membrane tethers. It also competitively inhibits YopH (Ki = 1.94 μM), a tyrosine phosphorylase secreted by Y. pestis into immune cells to block signal transduction, and anthrax lethal factor metalloproteinase, a component of anthrax toxin (IC50 = 6 μM). Synonyms: 4-[5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid; Leukadherin-1; Leukadherin 1; Leukadherin1; LA1. CAS No. 344897-95-6. Molecular formula: C22H15NO4S2. Mole weight: 421.48. | |
| Leukotriene B4-3-aminopropylamide | Leukotriene B4-3-aminopropylamide is a LTB4 analog that exhibits high binding affinity for BLT1 receptor. Synonyms: LTB4-3-aminopropylamide; (5S,6Z,8E,10E,12R,14Z)-N-(3-aminopropyl)-5,12-dihydroxyicosa-6,8,10,14-tetraenamide. Grades: ≥95%. CAS No. 89596-43-0. Molecular formula: C23H40N2O3. Mole weight: 392.6. | |
| Leukotriene B4 dimethyl amide | Leukotriene B4 dimethyl amide is a lipid mediator and Leukotriene B4 antagonist. It was shown to inhibit neutrophil degranulation induced by LTB4. Synonyms: LTB4 dimethyl amide; N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraen-1-amide. Grades: ≥97%. CAS No. 83024-92-4. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
| Leukotriene B4 ethanolamide | Leukotriene B4 ethanolamide is a potent antagonist of leukotriene B4 receptor with 3-fold higher affinity than leukotriene B4. It exhibits anti-inflammatory activity. Synonyms: LTB4-EA; (5S,12R)-5,12-Dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide. Grades: ≥97%. CAS No. 877459-63-7. Molecular formula: C22H37NO4. Mole weight: 379.5. | |
| Leukotriene B5 | Leukotriene B5 is a leukotriene generated from eicosapentaenoic acid (EPA). LTB5 exhibits less potent biological activity than LTB4, thus it can be identified as a LTB4 antagonist. Study showed that LTB5 inhibited LTB4-induced chemotaxis in vitro and LTB4-induced proliferation in cultured human epidermal keratinocytes. Synonyms: LTB5; 5,12-DiHEPE; 5S,12S-dihydroxy-6Z,8E,14Z,17Z-eicosapentanenoic acid. Grades: ≥98%. CAS No. 80445-66-5. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| Leukotriene C4 | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4; 5S,6R-Ltc(sub 4); 6R-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5S-hydroxyicosa-7E,9E,11Z,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.78. | |
| Leukotriene C4 methyl ester | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4 methyl ester; Leukotriene C4 monomethyl ester. Grades: ≥97%. CAS No. 73958-10-8. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
| Leukotriene D4 | Leukotriene D4 is a constituent of slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-; Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinylglycine; Leukotriene D; LTD4. Grades: ≥97%. CAS No. 73836-78-9. Molecular formula: C25H40N2O6S. Mole weight: 496.66. | |
| Leukotriene D4 methyl ester | Leukotriene D4 methyl ester is a derivate of Leukotriene D4, which is a constituent of a slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: LTD4 methyl ester; Leukotriene D4 monomethyl ester; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; Glycine, N-[S-[1-(1-hydroxy-5-methoxy-5-oxopentyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteinylglycine. Grades: 95%. CAS No. 103476-23-9. Molecular formula: C26H42N2O6S. Mole weight: 510.69. | |
| Leukotriene E4 | Leukotriene E4 is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid; LTE4. Grades: ≥97%. CAS No. 75715-89-8. Molecular formula: C23H37NO5S. Mole weight: 439.61. | |
| Leukotriene E4 methyl ester | Leukotriene E4 methyl ester is a derivate of Leukotriene E4, which is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, 1-methyl ester, (5S,6R,7E,9E,11Z,14Z)-; 1-Methyl (5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoate; 7,9,11,14-Eicosatetraenoic acid, 6-[(2-amino-2-carboxyethyl)thio]-5-hydroxy-, 1-methyl ester, [5S-[5R*,6S*(S*),7E,9E,11Z,14Z]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteine; LTE4, methyl ester; leukotriene E4 monomethyl ester. Grades: ≥95%. CAS No. 89461-65-4. Molecular formula: C24H39NO5S. Mole weight: 453.64. | |
| Leupeptin | Leupeptin reversibly inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C). Leupeptin has been shown to inhibit activation-induced programmed cell death. Synonyms: 2-(2-acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-methylval; 2-(2-acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-valeramid; leupeptinac-ll; l-leucinamide,n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl; Leupeptin; Leupeptin Ac-LL; N-Acetyl-L-leucyl-L-leucyl-L-argininal; NK-381; NK 381; NK381. Grades: >98%. CAS No. 24365-47-7. Molecular formula: C20H38N6O4. Mole weight: 426.55. | |
| Levalbuterol | Levalbuterol is a short-acting beta 2 adrenergic agonist. Levalbuterol binds to beta 2 adrenergic receptors and activates intracellular adenyl cyclase to promote the convertion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). It is used to treat wheezing and shortness of breath caused by breathing problems (such as asthma, chronic obstructive pulmonary disease). Uses: The treatment of asthma. Synonyms: Levosalbutamol; (-)-Salbutamol; (-)-Albuterol; R-Salbutamol; 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol. CAS No. 34391-04-3. Molecular formula: C13H21NO3. Mole weight: 239.315. | |
| Levalbuterol tartrate | Levosalbutamol tartrate, the R-enantiomer of salbutamol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Uses: Used in the treatment of asthma and chronic obstructive pulmonary disease (copd). Synonyms: 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (α1R)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt); Xopenex HFA; Levosalbutamol tartrate. Grades: ≥98%. CAS No. 661464-94-4. Molecular formula: C13H21NO3.1/2(C4H6O6). Mole weight: 314.25. | |
| Levamisole | Levamisole, a thiazole derivative, has been found to be an antibiotic used to against parasitic worm infections and could also have potential activity in anticancer study. Uses: Adjuvants, immunologic. Synonyms: (s)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole;L-6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZOL(2,1-B) THIAZOLE;IMMUNOPURE(R) PHOSPHATASE SUPPRESSOR;LEVAMISOLE;LEVAMISOLE BASE;Imidazo2,1-bthiazole, 2,3,5,6-tetrahydro-6-phenyl-, (6S)-;lepuron;levomysol. Grades: 98%. CAS No. 14769-73-4. Molecular formula: C11H12N2S. Mole weight: 204.29. | |
| Levcromakalim | LevCromakalim is an ATP-sensitive K+channel(KATP) activator used in the management of hypertension in diabetes mellitus. Synonyms: (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile; BRL 38226; BRL 38227; BRL-34915; BRL-38226; BRL-38227; BRL38226; BRL38227; Cromakalim; Cromakalim, (3R-cis)-Isomer; Cromakalim, (3R-trans)-Isomer; Cromakalim, (3S-cis)-Isomer; Cromakalim, (3S-trans)-Isomer; Cromakalim, (trans)-Isomer; Lemakalim; Levcromakalim. CAS No. 94535-50-9. Molecular formula: C16H18N2O3. Mole weight: 286.33. | |
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