BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
A glycine derivative containing a Fmoc group and an alkyne side chain. It is a building block for the synthesis of cyclic peptides. Synonyms: Fmoc-L-homopropargylglycine; (2S)-2-(Fmoc-amino)-5-hexynoic acid. CAS No. 942518-21-0. Molecular formula: C21H19NO4. Mole weight: 349.4.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Hyp(tBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-O-(t-butyl)-trans-4-hydroxy-L-proline p-methoxybenzyl alcohol polyethyleneglycol resin.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Ile-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-L-isoleucine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Ile-Ser[Psi(Me,Me)Pro]-OH is used as a reactant in the synthesis of peptides and receptor targeting ligands. Synonyms: Fmoc-Ile-Ser[Psi(Me,Me)Pro]-OH; (S)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl]-2,2-dimethyloxazolidine-4-carboxylic acid; Fmoc-Ile-Ser(Psime,Mepro)-OH; 6904AH; (4S)-3-[(2S,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid. Grade: 99-101% (Assay by titration). CAS No. 1147996-34-6. Molecular formula: C27H32N2O6. Mole weight: 480.56.
Fmoc-Ile-SH
Fmoc-Ile-SH. Synonyms: Fmoc Ile SH; (2S,3S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methyl-pentanethioic acid. CAS No. 881913-47-9. Molecular formula: C21H23NO3S. Mole weight: 369.48.
Fmoc-isothiocyanate (CAS# 199915-38-3) is used in biological studies for the preparation of aminothiazoline derivatives as tight-binding inhibitors of human protein O-acetylglucoaminidase. Synonyms: Fmoc-NCS. Grade: ≥ 95 % (NMR). CAS No. 199915-38-3. Molecular formula: C16H11NO2S. Mole weight: 281.3.
N-Fmoc-L-alanine is a Fmoc-protected form of L-Alanine. L-Alanine is used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development and is one of the 20 amino acids encoded by the genetic code. Synonyms: Fmoc-L-Ala-OH; N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-alanine Hydrate; Fmoc-Ala-OH Hydrate; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid; 9-fluorenylmethoxycarbonyl-Ala-OH; Fmoc-L-alpha-Alanine. Grade: ≥ 99.8% (Chiral HPLC). CAS No. 35661-39-3. Molecular formula: C18H17NO4. Mole weight: 311.30.
Fmoc-L-alanine-2-chlorotrityl resin
Pre-loaded resins for solid phase peptide and organic synthesis. Synonyms: Fmoc-Ala-2-chlorotrityl resin.
Fmoc-L-alanine 4-alkoxybenzyl alcohol resin
Pre-loaded resins for solid phase peptide and organic synthesis. Synonyms: Fmoc-L-Ala-Wang resin.
Pre-loaded resins for solid phase peptide and organic synthesis.
Fmoc-L-aspartic acid
N-Fmoc-L-aspartic acid is an N-Fmoc-protected form of L-Aspartic acid. L-Aspartic acid is a non-essential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system. Synonyms: Fmoc-L-Asp-OH; Fmoc-Asp-OH; N-Fmoc-L-aspartic acid; N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-aspartic Acid; Fmoc-L-aspartic acid. Grade: ≥ 99% (HPLC). CAS No. 119062-05-4. Molecular formula: C19H17NO6. Mole weight: 355.35.
Fmoc-L-aspartic acid 4-alkoxybenzyl alcohol resin
Pre-loaded resins for solid phase peptide and organic synthesis. Synonyms: Fmoc-L-Asp-Wang resin.
The Dmab group can be cleaved selectively in the presence of tBu-based protected groups by treatment with 2% hydrazine in DMF, making this derivative an extremely useful tool for the preparation of cyclic peptides by FMOC SPPS. Synonyms: Fmoc-L-Asp-ODmab; N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-aspartic acid 1-[4-[1-[2,6-dioxo-4,4-dimethylcyclohexylidene]-3-methylbutylamino]benzyl] ester. Grade: ≥ 98% (HPLC). CAS No. 172611-77-7. Molecular formula: C39H42N2O8. Mole weight: 666.70.
Fmoc-L-aspartic acid α-4-nitroanilide
Useful for the solid phase synthesis of peptides-4-nitroanilides on 2-chlorotrityl resins. Synonyms: Fmoc-L-Asp-pNA; (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(4-nitroanilino)-4-oxobutanoic acid. Grade: ≥ 98% (HPLC). CAS No. 185547-52-8. Molecular formula: C25H21N3O7. Mole weight: 475.46.