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Fmoc-Thr(tBu)-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Thr(tBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-O-(t-butyl)-L-threonine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Thr(tBu)-Phe-OH is a protected dipeptide used in peptide synthesis. It includes an Fmoc (Fluorenylmethyloxycarbonyl) group protecting the N-terminus, preventing unwanted reactions during assembly. The Thr (Threonine) residue is protected at its hydroxyl side chain with a tBu (tert-butyl) group, safeguarding it from side reactions. Phe (Phenylalanine) is the second amino acid in the sequence, contributing aromatic properties. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is used to introduce threonine and phenylalanine residues into peptides, with specific protections in place to allow for controlled synthesis. Synonyms: N-(Fluorenylmethoxycarbonyl)-O3-tert-butyl-L-threonyl-L-phenylalanine; (N-Fmoc-O-tert-butyl-L-threoninyl)-L-phenylalanine; N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine; (2S)-2-[(2S,3R)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-phenylpropanoic acid; TF; Fmoc-Thr(OtBu)-Phe-OH. Grade: ≥95%. CAS No. 1962160-86-6. Molecular formula: C32H36N2O6. Mole weight: 544.65.
Fmoc-Thr(tBu)-Phe-Thr(tBu)-OH
Fmoc-Thr(tBu)-Phe-Thr(tBu)-OH is a protected tripeptide used in peptide synthesis. The Fmoc (Fluorenylmethyloxycarbonyl) group protects the N-terminus of the threonine (Thr) residue, preventing it from reacting during synthesis. The hydroxyl groups on the side chains of both threonine residues are protected by tBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is performed. Phe (Phenylalanine), the central amino acid, adds aromatic and hydrophobic characteristics to the peptide. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is utilized to introduce threonine and phenylalanine into peptides, with specific protections to control the reactivity of the functional groups, ensuring efficient and selective peptide synthesis. Synonyms: TFT; N-N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threonine. Grade: ≥95%. Molecular formula: C40H51N3O8. Mole weight: 701.86.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Tic-Wang Resin; (S)-N-(9-Fluorenylmethoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid p-methoxybenzyl alcohol resin.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Trp-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-L-tryptophan p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Trp(Boc)-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Trp(Boc)-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Trp(Boc)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-1-(t-butoxycarbonyl)-L-tryptophan p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Trp(Boc)-Alko Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Trp(Boc)-Wang Resin; N-α-(9-Fluorenylmethoxycarbonyl)-1-(t-butoxycarbonyl)-L-tryptophan p-methoxybenzyl alcohol resin.
Excellent resin for the synthesis of peptide acids using Fmoc strategy. Cleavage can be effected by 95% TFA.
Fmoc-Trp(Mts)-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Trp(Mts)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-1-mesitylene-2-sulfonyl-L-tryptophan p-methoxybenzyl alcohol polyethyleneglycol resin.
Excellent resin for the synthesis of peptide acids using Fmoc strategy. Cleavage can be effected by 95% TFA. Synonyms: Fmoc-L-Trp-Wang resin; Nα-Fmoc-L-tryptophan 4-alkoxybenzyl alcohol resin.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Tyr(tBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-O-(t-butyl)-L-tyrosine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Val-Ala-Osu. Synonyms: Fmoc Val Ala Osu. Molecular formula: C28H29N3O9. Mole weight: 551.54.
Fmoc-Val-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Val-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-L-valine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Val-Cit-OH
Fmoc-Val-Cit-OH. Synonyms: Fmoc Val Cit OH; (S)-2-((S)-2-((((9H-Fluoren-9-YL)methoxy)carbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid. CAS No. 159858-21-6. Molecular formula: C26H32N4O6. Mole weight: 496.6.