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5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C35H38Cl2N8O4. CAS No. 84625-61-6. Prepack ID 45052670-5g. Molecular Weight 705.63. See USA prepack pricing.
Itraconazole-d3
2H Labeled Compounds. Alternative Names: (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methyl-d3-propyl)-3H-1,2,4-triazol-3-one; Itrizole-d3; Oriconazole-d3; R-51211-d3; Sporamelt-d3; Sporanox-d3; Triasporin-d3. CAS No. 1217512-35-0. Molecular formula: C35H35D3Cl2N8O4. Mole weight: 708.65. Appearance: Off-White to Light Beige Solid. Catalog: ACM1217512350.
Itraconazole-d5
An isotopically labeled, orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Itraconazole D9
2H Labeled Compounds. Alternative Names: 4-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(butan-2-yl-d9)-2,4-dihydro-3H-1,2,4-triazol-3-one. CAS No. 1217516-26-1. Mole weight: 714.7. Purity: >95%. Catalog: ACM1217516261.
Itraconazole EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 252964-68-4. Molecular Formula: C23H29N5O2. Mole Weight: 407.52. Catalog: APB252964684.
Itraconazole EP Impurity B
Itraconazole EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 854372-77-3. Molecular Formula: C35H38Cl2N8O4. Mole Weight: 705.64. Catalog: APB854372773.
Itraconazole EP Impurity C
Itraconazole EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 74855-91-7. Molecular Formula: C34H36Cl2N8O4. Mole Weight: 691.61. Catalog: APB74855917.
Itraconazole EP Impurity D
Itraconazole EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89848-49-7. Molecular Formula: C34H36Cl2N8O4. Mole Weight: 691.61. Catalog: APB89848497.
Itraconazole EP Impurity E
Itraconazole EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 252964-65-1. Molecular Formula: C35H38Cl2N8O4. Mole Weight: 705.64. Catalog: APB252964651.
Itraconazole EP Impurity F
Itraconazole EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89848-51-1. Molecular Formula: C35H38Cl2N8O4. Mole Weight: 705.64. Catalog: APB89848511.
Itraconazole EP Impurity G
Itraconazole EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C44H41Cl4N11O6. Mole Weight: 961.68. Catalog: APB08128.
An orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Alternative Names: Oriconazole, Sporanox, Triasporin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
an impurity of Itraconazole. Synonyms: 4-(4-(7-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-2,3-dihydro-1H-benzo[e][1,4]diazepin-4(5H)-yl)phenyl)-1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one. Grades: > 95%. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.62.
Itraconazole Sulfonate Impurity
An intermediate in the synthesis of Itraconazole. Synonyms: cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate; (2R,4R)-rel-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Methanesulfonate. Grades: > 95%. CAS No. 67914-86-7. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.26.
ITSA1 is a cell-permeable HDAC activator via inhibition of trichostatin A (TSA), which is a reversible inhibitor of HDAC. ITSA1 was showed to specifically counteract TSA-induced cell cycle arrest, histone acetylation, transcriptional activation, and cytoplasmic alpha-tubulin acetylation. Synonyms: ITSA-1; ITSA 1; N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide. Grades: ≥95%. CAS No. 200626-61-5. Molecular formula: C13H7Cl2N3O. Mole weight: 292.1.
Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 200626-61-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Iturin A
Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322.
ITX3
ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs. Synonyms: ITX 3; ITX-3. Grades: >98%. CAS No. 347323-96-0. Molecular formula: C22H17N3OS. Mole weight: 371.45.
ITX 3
ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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ITX-5061
ITX-5061 is a scavenger receptor B1 antagonist. Preclinical studies show that ITX-5061 is a selective inhibitor of HCV entry into hepatocytes. It can prevent virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA were on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide;1252679-52-9 (HCl salt). Grades: 98%. CAS No. 848144-15-0. Molecular formula: C30H37N3O7S. Mole weight: 583.70.
ITX-5061 HCl
This active molecular is a scavenger receptor B1 antagonist under the development by iTherX Pharmaceuticals for the treatment of Hepatitis C. ITX-5061 shows a special mechanism of action that prevents the hepatitis C virus from entering liver cells. Preclinical studies have shown that ITX-5061 can prevent virus binding/fusion and cell to cell spread. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA was on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; UNII-J4RA8K2Q2A; J4RA8K2Q2A;CHEMBL3402567;N-[5-tert-butyl-3-(methanesulfonamido)-2-methoxyphenyl]-2-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-2-oxoacetamide;hydrochloride;848144-15-0 (free base). Grades: 98%. CAS No. 1252679-52-9. Molecular formula: C30H38ClN3O7S. Mole weight: 620.16.
IU1
IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817.