A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Alternative Names: Oriconazole, Sporanox, Triasporin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
an impurity of Itraconazole. Synonyms: 4-(4-(7-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-2,3-dihydro-1H-benzo[e][1,4]diazepin-4(5H)-yl)phenyl)-1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one. Grades: > 95%. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.62.
Itraconazole Sulfonate Impurity
An intermediate in the synthesis of Itraconazole. Synonyms: cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate; (2R,4R)-rel-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Methanesulfonate. Grades: > 95%. CAS No. 67914-86-7. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.26.
ITSA1 is a cell-permeable HDAC activator via inhibition of trichostatin A (TSA), which is a reversible inhibitor of HDAC. ITSA1 was showed to specifically counteract TSA-induced cell cycle arrest, histone acetylation, transcriptional activation, and cytoplasmic alpha-tubulin acetylation. Synonyms: ITSA-1; ITSA 1; N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide. Grades: ≥95%. CAS No. 200626-61-5. Molecular formula: C13H7Cl2N3O. Mole weight: 292.1.
Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 200626-61-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Iturin A
Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322.
ITX3
ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs. Synonyms: ITX 3; ITX-3. Grades: >98%. CAS No. 347323-96-0. Molecular formula: C22H17N3OS. Mole weight: 371.45.
ITX 3
ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ITX-5061
ITX-5061 is a scavenger receptor B1 antagonist. Preclinical studies show that ITX-5061 is a selective inhibitor of HCV entry into hepatocytes. It can prevent virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA were on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide;1252679-52-9 (HCl salt). Grades: 98%. CAS No. 848144-15-0. Molecular formula: C30H37N3O7S. Mole weight: 583.70.
ITX-5061 HCl
This active molecular is a scavenger receptor B1 antagonist under the development by iTherX Pharmaceuticals for the treatment of Hepatitis C. ITX-5061 shows a special mechanism of action that prevents the hepatitis C virus from entering liver cells. Preclinical studies have shown that ITX-5061 can prevent virus binding/fusion and cell to cell spread. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA was on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; UNII-J4RA8K2Q2A; J4RA8K2Q2A;CHEMBL3402567;N-[5-tert-butyl-3-(methanesulfonamido)-2-methoxyphenyl]-2-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-2-oxoacetamide;hydrochloride;848144-15-0 (free base). Grades: 98%. CAS No. 1252679-52-9. Molecular formula: C30H38ClN3O7S. Mole weight: 620.16.
IU1
IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817.
IU1
IU1 is a cell-permeable, reversible and selective proteasome inhibitor of human USP14 with IC50 of 4.7 μ M, 25-fold selective to IsoT. Synonyms: IU 1; IU-1; 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(pyrrolidin-1-yl)ethan-1-one. Grades: >98%. CAS No. 314245-33-5. Molecular formula: C18H21FN2O. Mole weight: 300.37.
IU1
IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IU1-47
IU1-47 is a potent and selective inhibitor of the proteasomal deubiquitinating enzyme USP14 (IC50 = 60 nM). IU1-47 has been shown to enhance protein degradation rate in cells using as a reporter the microtubule-associated protein tau. Synonyms: 1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone. Grades: ≥98% by HPLC. CAS No. 670270-31-2. Molecular formula: C19H23ClN2O. Mole weight: 330.85.
IUN78876
IUN78876, also known as 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one is a chemical reagent for research use. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IUN78876; IUN-78876; IUN 78876. Product Category: Others. Appearance: Solid powder. CAS No. 1638178-87-6. Molecular formula: C23H22F2N4O. Mole weight: 408.45. Purity: >98%. IUPACName: 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one. Canonical SMILES: O=C1N(CC2=CC=C(F)C=C2F)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4. Product ID: ACM1638178876. Alfa Chemistry ISO 9001:2015 Certified.
Ivabradine
Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155974-00-8. Pack Sizes: 1 mg. Product ID: HY-B0162.
Ivabradine-d3 Hydrochloride
Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences.
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-1g. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine hydrochloride
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-100mg. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine hydrochloride
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148849-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0162A.
Ivabradine Hydrochloride
Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ivabradine Impurity 1
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: [2-(2-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propylamino}-ethyl)-4,5-dimethoxy-phenyl]-acetic acid. Grades: 95%. CAS No. 1462470-54-7. Molecular formula: C27H38N2O6. Mole weight: 486.60.
Ivabradine Impurity 10
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: N-Propyl-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one; 7,8-dimethoxy-3-propyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one. Grades: > 95%. Molecular formula: C15H21NO3. Mole weight: 263.33.
Ivabradine Impurity 10 (free base)
Ivabradine Impurity 10 (free base). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2- (2- (2- ( (3- ( ( (3, 4-dimethoxybicyclo[4. 2. 0]octa-1 (6), 2, 4-trien-7-yl)methyl) (methyl)amino)propyl)amino)ethyl)-4, 5-dimethoxyphenyl)acetic acid. CAS No. 1462470-54-7. Molecular Formula: C27H38N2O6. Mole Weight: 486.6. Catalog: APB1462470547.
Ivabradine Impurity 11
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: (7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. Grades: 95%. CAS No. 1132667-04-9. Molecular formula: C12H17NO2. Mole weight: 207.27.
Ivabradine Impurity 12
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 7,8-Dimethoxy-3-(3-methylamino-propyl)-1,3,4,5-tetrahydro-benzo[d]azepin-2-one HCl. Grades: 95%. CAS No. 85175-52-6. Molecular formula: C16H25N2O3Cl. Mole weight: 328.83.
Ivabradine Impurity 13
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propyl}-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one. Grades: 95%. Molecular formula: C27H36N2O6. Mole weight: 484.58.
Ivabradine Impurity 14
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: Hydroxy Ivabradine; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-5-hydroxy-7,8-dimethoxy-2H-3-benzazepin-2-one. Grades: > 95%. CAS No. 2253977-80-7. Molecular formula: C27H36N2O6. Mole weight: 484.58.
Ivabradine Impurity 15
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-4,5-dihydro-7,8-dimethoxy-1H-3-benzazepine-1,2(3H)-dione; 2-Oxo-ivabradine Hydrochloride. Grades: 95%. CAS No. 1616710-50-9. Molecular formula: C27H35ClN2O6. Mole weight: 519.03.
Ivabradine Impurity 15
Ivabradine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl) -7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione hydrochloride. CAS No. 1616710-50-9. Molecular Formula: C27H34N2O6·HCl. Mole Weight: 519.03. Catalog: APB1616710509.
Ivabradine Impurity 16
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-[(3-hydroxy-4-methoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one; 3-Hydroxy Ivabradine; (S)-3-(3-(((3-Hydroxy-4-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one; 1,3,4,5-Tetrahydro-3-[3-[[[(7S)-3-hydroxy-4-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-7,8-dimethoxy-2H-3-Benzazepin-2-one. Grades: 95%. CAS No. 304464-98-0. Molecular formula: C26H34N2O5. Mole weight: 454.56.
Ivabradine Impurity 17
Cas No. 866783-13-3.
Ivabradine Impurity 18
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane; 1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine; 3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. Grades: 95%. CAS No. 73344-75-9. Molecular formula: C11H15NO2. Mole weight: 193.24.