American Chemical Suppliers
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| Product | Description |
|---|---|
| U0124 Quick inquiry Where to buy Suppliers range |
U0124 is an inactive analog of U0126 that can be used as a negative control. U0124 has no inhibitory effects on MEK at concentrations up to 100 M. Synonyms: Bis[amino (methylthio) methylene]butanedinitrile. Cas No. 108923-79-1. Molecular formula C8H10N4S2. Molecular weight 226.31. Fine Chemicals. |
| U0126 Quick inquiry Where to buy Suppliers range |
U0126 is a MAPK inhibitor with antitumor activity. It inhibits MEK1 and MEK2 with IC50 values of 72 nM and 58 nM, respectively. U0126 inhibits tumorigenicity of liver cancer stem cells. U0126 Other Name: U-0126; U 0126; 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene; (2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile. Molecular Formula: C18H16N6S2. CAS Number: 109511-58-2. Molecular weight 380.488. Categories: Laboratory AR Grades Available. |
| U0126 Quick inquiry Where to buy Suppliers range |
U0126 is a selective inhibitor of mitogen-activated protein kinase kinases, MEK-1 and MEK-2It is a weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4. Appearance: White to off-white crystalline solid; granular or powder. Molecular Weight: 380.49. Purity: >99%. Storage Store at or below -20 centigrade. Group: Inhibitors. Other Names: CFC3, MAPKK1, MEK1, MKK1, PRKMK1. CAS Number: 109511-58-2. CEI-1023. MAP2K1; mitogen-activated protein kinase kinase 1; mek1; mkk1; map2k2; mapkk1; prkmk1; MGC79636; NP_001008058; NM_001008057;. |
| U-0126 Quick inquiry Where to buy Suppliers range |
MEK inhibitor. Source: Synthetic. Appearance: White solid. Molecular Weight: 380.5. Purity: >98%. Storage -20 centigrade. Group: Inhibitors. CAS Number: 109511-58-2. CEI-1033. MEK, U-0126, 109511-58-2, C18H16N6S2. |
| U0126,>99% Where to buy Suppliers range |
U0126,>99%. Product No. U-6770. LC Laboratories |
| U0126-EtOH Quick inquiry Where to buy Suppliers range |
U0126 can inhibit MEK1 and MEK2 with IC50 of 72 nM and 58 nM. Molecular Weight: 426.56. Purity: >99%. Storage 2 years at -20centigrade Powder. Group: Inhibitors. Other Names: UO126 EtOH. CAS Number: 1173097-76-1. CEI-0160. U0126-EtOH, UO126 EtOH, 1173097-76-1, MEK1, MEK2, C20H22N6OS2, (2Z, 3Z)-2, 3-bis(amino(2-aminophenylthio)methylene)succinonitrile, ethanol, MAP2K1, MAP2K2. |
| U0126-EtOH Quick inquiry Where to buy Suppliers range |
U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0. 07 M/0. 06 M, 100-fold higher affinity for N3-S218E/S222D MEK than PD98059. Cas No. 1173097-76-1. Molecular formula C18H16N6S2. C2H6O. Molecular weight 426.56. Laboratory ACS Grades Available. |
| U-101440E Where to buy Suppliers range |
U-101440E see its active ingredient, namely Irinotecan, Hydrochloride Salt, Trihydrate. LC Laboratories |
| U 18666A Where to buy Suppliers range |
U 18666A is a cell-permeable and amphiphilic amino-steroid that inhibits cholesterol synthesis and cellular transport via the suppression of 2,3-oxidosqualene-lanosterol cyclase activity. U 18666A also acts as a weak inhibitor of hedgehog (Hh) signaling. Synonyms: (3 ) -3-[2- (Diethylamino) ethoxy]androst-5-en-17-one hydrochloride. Cas No. 3039-71-2. Molecular formula C25H41NO2. HCl. Molecular weight 424.07. Laboratory Reagents. |
| U-29135 Where to buy Suppliers range |
U-29135 see its active ingredient, namely Geldanamycin. LC Laboratories |
| U-44069 Quick inquiry Where to buy Suppliers range |
U-44069 Other Name: U 44069; U44069; 9,11-dideoxy-9%26alpha%3b,11%26alpha%3b-epoxymethano PGF2%26alpha%3b; 9,11-dideoxy-9%26alpha%3b,11%26alpha%3b-epoxymethano Prostaglandin F2%26alpha%3b; 9,11-epoxymethano Prostaglandin H2. Molecular Formula: C21H34O4. CAS Number: 56985-32-1. Molecular weight 350.5. Categories: Reagent Grade Laboratory Chemicals. |
| U 46619 Where to buy Suppliers range |
U 46619 is a PGH2 (TXA2) analog that is reported to be a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0. 035 M). U 46619 has been shown to stimulate TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various Synonyms: (5Z) -7-[ (1R, 4S, 5S, 6R) -6-[ (1E, 3S) - 3- Hydroxy- 1- octenyl] - 2- oxabicyclo [ 2.2.1] hept- 5- yl] - 5- heptenoic acid. Cas No. 56985-40-1. Molecular formula C21H34O4. Molecular weight 350.5. Reagent Grade Chemicals. |
| U-51605 Quick inquiry Where to buy Suppliers range |
U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). U-51605 is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases, as well as a partial agonist at TP receptors. U-51605 Other Name: U 51605; U51605; 7-(6-Oct-1-enyl-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl)hept-5-enoic acid. Molecular Formula: C20H32N2O2. CAS Number: 64192-56-9. Molecular weight 332.5. Categories: Laboratory Chemicals. |
| U-54494A hydrochloride Quick inquiry Where to buy Suppliers range |
U-54494A hydrochloride is a -opioid agonist and a potential NMDA antagonist. U-54494A hydrochloride is used as an anticonvulsant. Synonyms: cis- (±) -3, 4-Dichloro-N-methyl-N-[2- (1-pyrrolidinyl) cyclohexyl]benzamide hydrochloride. Cas No. 112465-94-8. Molecular formula C18H24Cl2N2O. HCl. Molecular weight 391.77. Laboratory AR Grades Available. |
| U66858 Where to buy Suppliers range |
U66858, also known as Bunaprolast, is a hydroquinone inhibitor of leukotriene synthesis, which inhibits LTB4 production in human whole blood. Synonyms: (2- butyl- 4- methoxynaphthalen- 1- yl) acetate; 1- acetoxy- 2- n- butyl- 4- methoxynaphthalene; bunaprolast; U 66, 858; U 66858; U-66, 858; U-66858. Cas No. 99107-52-5. Molecular formula C17H20O3. Molecular weight 272.34. Laboratory Chemicals. |
| U-73122 Where to buy Suppliers range |
U-73122 is a phospholipase C inhibitor originated by Pharmacia Corporation and IC 50 value is 1. 0-2. 1 M in neutrophils and human platelets. U-73122 can be used as a tool to investigate the involvement of the PLC (phosphoinositide-specific phospholipase C Synonyms: 1- (6- ( ( (8R, 9S, 13S, 14S, 17S) -3-methoxy-13-methyl-7, 8, 9, 11, 12, 13, 14, 15, 16, 17- decahydro- 6H- cyclopenta [ a] phenanthren- 17- yl) amino) hexyl) -1H-pyrrole-2, 5-dione. Cas No. 112648-68-7. Molecular formula C29H40N2O3. Molecular weight 464.64. Reagent Grade Chemicals. |
| U-73343 Quick inquiry Where to buy Suppliers range |
U-73343 is a analog of U 73122, and can be used as a negative control for phospholipase C inhibition in mechanically stimulated and its neighboring cells. It can also be used for studying the role of phospholipase C signaling in modulating epithelial Na+ Synonyms: 1-[6-[[ (17b) -3-methoxyestra-1, 3, 5 (10) -trien-17-yl]amino]hexyl]-2, 5-pyrrolidinedione. Cas No. 142878-12-4. Molecular formula C29H42N2O3. Molecular weight 466.66. Laboratory AR Grades Available. |
| U-74389G Quick inquiry Where to buy Suppliers range |
Synonyms: U- 74389G; (Z) - 2- BUTENEDIONATE; 21- (4- (2, 6 DI- 1- PYRROLIDINYL- 4- PYRIMIDINYL) - 1- PIPERAZINYL) - PREGNA- 1, 4, 9 (11) - TRIENE- 3, 20- DIONE; 21- (4- (2, 6 DI- 1- PYRROLIDINYL- 4- PYRIMIDINYL) - 1- PIPERAZINYL) - PREGNA- 1, 4, 9 (11) - TRIENE- 3, 20- DIONE (Z) - 2- BUTENEDIONATE; 21- (4- (2, 6- DI-. Cas No. 153190-29-5. Molecular formula C41H54N6O6. Molecular weight 726.9. Laboratory ACS Grades Available. |
| U-75302 Quick inquiry Where to buy Suppliers range |
U-75302 is a selective LTB4 receptor antagonist with Ki value of 159 nM on guinea pig lung membranes. U-75302 Other Name: U 75302; U75302; 6-(6-(3-Hydroxy-1,5-undecadien-1-yl)-2-pyridinyl)-1,5-hexanediol. Molecular Formula: C22H35NO3. CAS Number: 119477-85-9. Molecular weight 361.5. Categories: Laboratory Reagents Grade. |
| U-75875 Quick inquiry Where to buy Suppliers range |
U-75875 is a protease inhibitor. It is also a peptidomimetic inhibitor and could inhibit HIV-1 gag-pol protein. It completely blocked HIV replication in human peripheral blood mononuclear cells and in a continuous cell line. It can be used as therapeutic Synonyms: U75875; N- (1- Naphtyloxyacetyl) - L- His- [ (2R, 3R, 4R, 5S) - 3, 4- dihydroxy- 2- isopropyl- 5- (cyclohexylmethyl) - 5- amino*pentanoyl] - L- Ile- (2- pyridylmethyl) NH2; PNU- 75875; (2R, 3R, 4R, 5S) - 6- cyclohexyl- 3, 4- dihydroxy- 5- [ [ (2S) - 3- (1H- imidazol- 5- yl) - 2- [ (2- naphthalen- 1- yloxyacetyl. Cas No. 112190-24-6. Molecular formula C45H61N7O7. Molecular weight 812.02. Laboratory ACS Grades Available. |
| U89232 Quick inquiry Where to buy Suppliers range |
U89232, a cardioselective cyanoguanidine analog of cromakalim, appears to be a cardioselective KATP channel opener. Synonyms: 1- cyano- 2- [ (3R, 4S) - 6- cyano- 3- hydroxy- 2, 2- dimethyl- 3, 4- dihydrochromen- 4- yl] - 3- (2- methylbutan- 2- yl) guanidine; Guanidine, N- cyano- N'- (6- cyano- 3, 4- dihydro- 3- hydroxy- 2, 2- dimethyl- 2H- 1- benzopyran- 4- yl) - N''- (1, 1- dimethylpropyl) - , trans-; trans- N- cyano- N'- (6- cyan. Cas No. 134017-78-0. Molecular formula C19H25N5O2. Molecular weight 355.43. Reagent Grade Laboratory Chemicals. |
| U 89843A Quick inquiry Where to buy Suppliers range |
U 89843A is a positive allosteric modulator of GABAA receptors. U 89843A potentiates GABA-induced Cl- currents in the 1 2 2, 3 2 2 and 6 2 2 GABAA receptors. U 89843A exhibits sedative activity following i. v. administration without losing "righting ref Synonyms: 6, 7-Dimethyl-2, 4-di-1-pyrrolidinyl-7H-pyrrolo[2, 3-d]pyrimidine hydrochloride. Cas No. 157013-85-9. Molecular formula C16H23N5. HCl. Molecular weight 321.85. Reagent Grade Chemicals. |
| U 90042 Where to buy Suppliers range |
U 90042 is a GABAA receptor ligand binding to three receptor subtypes: 1 2 2, 3 2 2 and 6 2 2 (Ki = 7. 8, 9. 5 and 11. 0 nM, respectively). U 90042 potentiates GABA-induced chloride currents in 6 2 2 receptors. U 90042 is used as a sedative/hypnotic. Synonyms: 11-Chloro-5- (5-cyclopropyl-1, 2, 4-oxadiazol-3-yl) -2, 3-dihydrodiimidazo[1, 5-a:1', 2'-c]quinazoline; ACMC-20ejs3. Cas No. 134516-99-7. Molecular formula C17H13ClN6O. Molecular weight 352.78. Laboratory Reagents. |
| U91356 Quick inquiry Where to buy Suppliers range |
U91356 exhibits good dopaminergic agonist activity, and has improved metabolic stability and oral bioavailability in the rat and monkey. Synonyms: 5-propylamino-5, 6-dihydro-4H-imidazo (4, 5, 1-ij) quinolin-2 (1H) -one; U 91356; U 91356A; U-91356; U-91356A; U91356A. Cas No. 152886-85-6. Molecular formula C13H17N3O. Molecular weight 231.29. Laboratory Reagents. |
| U 92016A Where to buy Suppliers range |
U 92016A is an orally bioactive 5-HT1A full agonist with high intrinsic activity. Hypothermia, hypotension and 5-HT behavioral syndrome are caused by administration of U 92016A. Synonyms: (8R) -8- (dipropylamino) -6, 7, 8, 9- tetrahydro- 3H- benzo [ e] indole- 2- carbonitrile hydrochloride. Cas No. 149654-41-1. Molecular formula C19H25N3. HCl. Molecular weight 331.88. Laboratory Reagents. |
| U-93631 Quick inquiry Where to buy Suppliers range |
U 93631 is a ligand at the picrotoxin site of GABA(A) receptors, allosterically antagonizing GABA-induced Cl- currents. U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A recep Synonyms: 4, 5-Dihydro-4, 4-dimethyl-imidazo[1, 5-a]quinoxaline-3-carboxylic acid 1, 1-dimethylethyl ester; U93631, U-93631, U 93631. Cas No. 152273-12-6. Molecular formula C17H21N3O2. Molecular weight 299.37. Reagent Grade Laboratory Chemicals. |
| U 99194 maleate Quick inquiry Where to buy Suppliers range |
U 99194 maleate is a potent and selective dopamine D3 antagonist (Ki = 160, 2281 and > 10000 nM for human cloned D3, D2 and D4 receptors, respectively). Synonyms: 2, 3-Dihydro-5, 6-dimethoxy-N, N-dipropyl-1H-inden-2-amine maleate; 5, 6-Dimethoxy-2- (di-n-propylamino) indan maleate. Cas No. 234757-41-6. Molecular formula C17H27NO2. C4H4O4. Molecular weight 393.48. Fine Chemicals. |
| UA 62784 Quick inquiry Where to buy Suppliers range |
UA 62784, under the IUPAC name 4-[5-(4-methoxyphenyl)-1,3-oxazol-2-yl]fluoren-9-one, a cytotoxic microtubule inhibitor in vitro, causes reversible cell cycle arrest in mitosis before metaphase, which leads to apoptosis. It is also a novel specific inhibit Synonyms: 4- [5- (4- methoxyphenyl) - 1, 3- oxazol- 2- yl] fluoren- 9- one; UA62784; 313367- 92- 9; 4- [5- (4- methoxyphenyl) - 1, 3- oxazol- 2- yl] - 9H- fluoren- 9- one; AC1MPDKY; Oprea1_740865; SCHEMBL14765347; CTK8E8877; DTXSID20391982; ZINC1512677; AKOS024458074; PL053830; 4- [5- (4- Methox. Cas No. 313367-92-9. Molecular formula C23H15NO3. Molecular weight 353.37. Laboratory ACS Grades Available. |
| UA8967 Quick inquiry Where to buy Suppliers range |
UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 1261 M for exposure times of 72 h. Synonyms: UA-8967; UA 8967. Cas No. 17511-50-1. Molecular formula C20H23N3. Molecular weight 305.425. Fine Chemicals. |
| UAA crosslinker 1 Quick inquiry Where to buy Suppliers range |
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA syn. UAA crosslinker 1 Other Name: 2-amino-6-(2-azidoethoxycarbonylamino)hexanoic acid. Molecular Formula: C9H17N5O4. CAS Number: 1167421-25-1. Molecular weight 259.26. Categories: Laboratory ACS Grades Available. |
| UAA crosslinker 1 hydrochloride Quick inquiry Where to buy Suppliers range |
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA syn. UAA crosslinker 1 hydrochloride Other Name: 2-amino-6-(2-azidoethoxycarbonylamino)hexanoic acid hydrochloride. Molecular Formula: C9H18ClN5O4. CAS Number: 1994331-17-7. Molecular weight 295.72. Categories: Laboratory Reagents Grade. |
| UAB30 Quick inquiry Where to buy Suppliers range |
UAB30 is a low-toxicity retinoid X receptor-selective agonist selective for the binding and activation of RXRs over RAR' s. UAB30 is highly effective in the prevention of breast cancers in a rat model. Synonyms: (2E, 4E, 6Z, 8E) - 8- (3, 4- dihydro- 2H- naphthalen- 1- ylidene) - 3, 7- dimethylocta- 2, 4, 6- trienoic acid; (9Z) - UAB30; 8- (3', 4'- dihydro- 1' (2'H) - naphthalen- 1'- ylidene) - 3, 7- dimethyl- 2, 4, 6- octatrienoic acid; 9- cis- UAB30; 9cUAB30; UAB 30; UAB- 30. Cas No. 205252-59-1. Molecular formula C20H22O2. Molecular weight 294.39. Laboratory Reagents. |
| UAMC00039 dihydrochloride Quick inquiry Where to buy Suppliers range |
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor (IC50= 0. 48 nM) with selectivity against DPP-9, DPP-8 and DPP-IV (IC50= 78. 6, 142 and 165 M, respectively). Synonyms: (2S) -2-amino-4-[ (4-chlorophenyl) methyl amino] - 1- piperidin- 1- ylbutan- 1- one; dihydrochloride; N- (4-chlorobenzyl) -4-oxo-4- (1-piperidinyl) -1, 3- (S) -butane-diamine hydrochloride. Cas No. 697797-51-6. Molecular formula C16H26Cl3N3O. Molecular weight 382.76. Reagent Grade Laboratory Chemicals. |
| UAMC-3203 Quick inquiry Where to buy Suppliers range |
UAMC-3203 is a ferroptosis inhibitor with IC50 value of 10 nM. UAMC-3203 Other Name: UAMC 3203; UAMC3203; 3-(Benzylamino)-4-(cyclohexylamino)-N-(2-piperazin-1-ylethyl)benzenesulfonamide. Molecular Formula: C25H37N5O2S. CAS Number: 2271358-64-4. Molecular weight 471.66. Categories: Reagent Grade Laboratory Chemicals. |
| UB 165 fumarate Quick inquiry Where to buy Suppliers range |
UB 165 fumarate is a full agonist at 3 2- and a weak partial agonist at 4 2- containing nAChRs (Ki = 0. 27, 20 (IC50), 2790 and 990 nM for 4 2, 3, 7 and 1 1 - respectively). Synonyms: 2- (6-Chloro-3-pyridinyl) -9-azabicyclo[4.2.1]non-2-ene fumarate. Cas No. 200432-86-6. Molecular formula C13H15ClN2. C4H4O4. Molecular weight 350.8. Fine Chemicals. |
| Ubidecarenone Quick inquiry Where to buy Suppliers range |
Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. Synonyms: CoQ10. Cas No. 303-98-0. Molecular formula C59H90O4. Molecular weight 863.34. Laboratory AR Grades Available. |
| Ubiquinol Where to buy Suppliers range |
Ubiquinol. CAS No: 992-78-9 |
| ubiquinol oxidase (electrogenic, non H+-transporting) Quick inquiry Where to buy Suppliers range |
This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1. The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 1. 10. 3. 10, ubiquinol oxidase (H+-transporting). ubiquinol oxidase (electrogenic, non H+-transporting) Group: Enzymes. Alternative Name: cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol: O2 oxidoreductase (electrogenic, non H+-transporting). Global enzyme suppliers, distributors and manufacturers. |
| ubiquinol oxidase (H+-transporting) Quick inquiry Where to buy Suppliers range |
Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo3 oxidase it is 2, while for the bd-II oxidase it is 1. cf. EC 1. 10. 3. 14, ubiquinol oxidase (electrogenic, non H+-transporting). ubiquinol oxidase (H+-transporting) Group: Enzymes. Alternative Name: cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol: O2 oxidoreductase (H+-transporting). Global specialty enzymes. |
| ubiquinol oxidase (non-electrogenic) Quick inquiry Where to buy Suppliers range |
The enzyme, described from the mitochondria of plants and some fungi and protists, is an alternative terminal oxidase that is not sensitive to cyanide inhibition and does not generate a proton motive force. Unlike the electrogenic terminal oxidases that contain hemes (cf. EC 1. 10. 3. 10 and EC 1. 10. 3. 14), this enzyme contains a dinuclear non-heme iron complex. The function of this oxidase is believed to be dissipating excess reducing power, minimizing oxidative stress, and optimizing photosynthesis in response to changing conditions. ubiquinol oxidase (non-electrogenic) Group: Enzymes. Alternative Name: plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol: O2 oxidoreductase (non-electrogenic). Enzyme manufacturers USA. |
| UBIQUINOL (REDUCED COENZYME Q10) Quick inquiry Where to buy Suppliers range |
Cas No. 3073-95-8. Laboratory Chemicals. |
| Ubiquinone-10 Quick inquiry Where to buy Suppliers range |
Ubiquinone-10 acts as an inhibitor of the mitochondrial permeability transition pore (MPTP). This inhibitory effect can be counteracted by ubiquinone-5. Uses: An inhibitor of the mitochondrial permeability transition pore. Group: Coenzymes. Alternative Name: Coenzyme Q2; 2, 3-Dimethoxy-5-methyl-6-geranyl-1, 4-benzoquinone. CAS Number: 606-06-4. American enzyme company. |
| UBIQUINONE-11 Quick inquiry Where to buy Suppliers range |
UBIQUINONE-11 Other Name: UBIQUINONE-11; coenzyme Q11; 2,3-Dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyl-2,6,10,14,18,22,26,30,34,38,42-tetratetracontaundecenyl]-2,5-cyclohexadiene-1,4-dione; Ubiquinone Q11. Molecular Formula: C64H98O4. CAS Number: 24663-35-2. Molecular weight 931.46. Categories: Laboratory ACS Grades Available. |
| Ubiquinone-5 Quick inquiry Where to buy Suppliers range |
Ubiquinone-5 is a coenzyme Q10 (CoQ10) (sc-205262) analog that counteracts the inhibitory effects on mitochondrial permeability transition pore (MPTP) of decylubiquinone and ubiquinone-10. Uses: A CoQ10 analog that counteracts the inhibitory effects on MPTP. Group: Coenzymes. Alternative Name: Coenzyme Q1. CAS Number: 727-81-1. Enzyme manufacturers USA. |
| Ubiquitin Isopeptidase Inhibitor I, G5 Quick inquiry Where to buy Suppliers range |
Ubiquitin Isopeptidase Inhibitor I, G5, a cell-permeable cross-conjugated unsaturated dienone compound, is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1. 76 and 1. 6 M in E1A and E1A/C9DN cells, respectively. Synonyms: 3, 5-bis[ (4-nitrophenyl) methylidene]-1, 1-dioxothian-4-one. Cas No. 108477-18-5. Molecular formula C19H14N2O7S. Molecular weight 414.39. Laboratory Reagents. |
| ubiquitinyl hydrolase 1 Quick inquiry Where to buy Suppliers range |
Links to polypeptides smaller than 60 residues are hydrolysed more readily than those to larger polypeptides. Isoforms exist with quantitatively different specificities, amongst the best known being UCH-L1 and UCH-L3, which are major proteins of the brain of mammals. Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde). Ubiquitinyl hydrolase 1 is the type example of peptidase family C12, with a similar protein fold to papain and catalytic amino acids Cys, His and Asp. There is a separate family (C19) of enzymes that also hydrolyse ubiquitinyl bonds, and it is thought that all the ubiquitinyl hydrolases are also ubiquitin thiolesterases (EC 3. 1. 2. 15). ubiquitinyl hydrolase 1 Group: Enzymes. Alternative Name: ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. CAS Number: 86480-67-3, 189642-63-5. American enzyme company. |
| UBP1112 Quick inquiry Where to buy Suppliers range |
UBP1112 is a selective group III mGlu receptor antagonist (apparent Kd = 5. 1 and 488 M for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors). Synonyms: - Methyl- 3- methyl - 4- phosphonophenylglycine; 2-amino-2- (3-methyl-4-phosphonophenyl) propanoic acid. Cas No. 339526-74-8. Molecular formula C10H14NO5P. Molecular weight 259.2. Reagent Grade Laboratory Chemicals. |
| UBP 282 Quick inquiry Where to buy Suppliers range |
UBP 282 is an AMPA and kainate receptor antagonist. UBP 282 inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres. Synonyms: ( S) - -Amino-3-[ (4-carboxyphenyl) methyl]-3, 4-dihydro-2, 4-dioxo-1 (2H) -pyrimidinepropanoic acid; VBP. Cas No. 544697-47-4. Molecular formula C15H15N3O6. Molecular weight 333.3. Fine Chemicals. |
| UBP 296 Quick inquiry Where to buy Suppliers range |
UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1. 09 M) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. It has no activity at NM Synonyms: (RS) -1- (2-Amino-2-carboxyethyl) -3- (2-carboxybenzyl) pyrimidine-2, 4-dione; 2-[[3- (2-amino-2-carboxyethyl) -2, 6- dioxopyrimidin- 1- yl] methyl ] benzoic acid. Cas No. 745055-86-1. Molecular formula C15H15N3O6. Molecular weight 333.3. Laboratory Analytical Grades Available. |
| UBP 301 Quick inquiry Where to buy Suppliers range |
UBP 301 is a potent kainate receptor antagonist (apparent Kd = 5. 94 M), displaying ~ 30-fold selectivity over AMPA receptors. Synonyms: ( S) - -Amino-3-[ (4-carboxyphenyl) methyl]-3, 4-dihydro-5-iodo-2, 4-dioxo-1 (2H) -pyrimidinepropanoic acid; 4-[[3-[ (2S) - 2- amino- 2- carboxyethyl] - 5- iodo- 2, 6- dioxopyrimidin- 1- yl] methyl ] benzoic acid. Cas No. 569371-10-4. Molecular formula C15H14IN3O6. Molecular weight 459.2. Laboratory ACS Grades Available. |
| UBP 302 Quick inquiry Where to buy Suppliers range |
UBP 302 is a potent and selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 402 nM) that displays ~ 260-fold selectivity over AMPA receptors, ~ 90-fold selectivity over recombinant human GLUK6- and GLUK2-containing kainat Synonyms: (S) -1- (2-Amino-2-carboxyethyl) -3- (2-carboxybenzyl) pyrimidine-2, 4-dione; 2-[[3-[ (2S) -2-amino-2-carboxyethyl]-2, 6- dioxopyrimidin- 1- yl] methyl ] benzoic acid. Cas No. 745055-91-8. Molecular formula C15H15N3O6. Molecular weight 333.3. Reagent Grade Chemicals. |
| UBP 310 Quick inquiry Where to buy Suppliers range |
UBP 310 is a GLUK5 kainate receptor antagonist (IC50 = 130 nM), displaying 12,700-fold selectivity for GLUK5 over GLUK6. It has no activity at mGlu group I or NMDA receptors at concentrations of up to 10 M. UBP 310 also blocks recombinant homomeric GLUK7 Synonyms: (S) -1- (2-Amino-2-carboxyethyl) -3- (2-carboxy-thiophene-3-yl-methyl) -5-methylpyrimidine-2, 4-dione; 3-[[3- (2-amino-2-carboxyethyl) -5-methylidene-2, 6- dioxopyrimidin- 3- ium- 1- yl] methyl ] thiophene- 2- carboxylic acid. Cas No. 902464-46-4. Molecular formula C14H15N3O6S. Molecular weight 353.35. Laboratory Reagents. |
| Ubrogepant Quick inquiry Where to buy Suppliers range |
Ubrogepant is and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist originated by Merck & Co. In Sep 2016, Allergan initiated a phase III extension trial for Migraine in USA. Synonyms: (3S) -1, 2, 5, 7-Tetrahydro-N-[ (3S, 5S, 6R) -6-methyl-2-oxo-5-phenyl-1- (2, 2, 2-trifluoroethyl) - 3- piperidinyl] - 2- oxo- spiro [ 6H- cyclopenta [ b] pyridine- 6, 3-[3H]pyrrolo[2, 3-b]pyridine]-3-carboxamide;. Cas No. 1374248-77-7. Molecular formula C29H26F3N5O3. Molecular weight 549.55. Fine Chemicals. |
| UC 112 Quick inquiry Where to buy Suppliers range |
UC-112 is an IAP inhibitor (IC50 values from 0. 7 - 3. 4 M). UC-112 also potently inhibits the growth of P-glycoprotein. Synonyms: 5- ( (benzyloxy) methyl) - 7- (pyrrolidin- 1- ylmethyl) quinolin- 8- ol; (Z, 6R) - 2- methyl- 6- [ (5R, 9R, 10R, 13R, 14R, 17R) - 4, 4, 10, 13, 14- pentamethyl- 3- oxo- 1, 2, 5, 6, 9, 11, 12, 15, 16, 17- decahydrocyclopenta [ a] phenanthren- 17- yl] hept- 2- enoic acid;. Cas No. 383392-66-3. Molecular formula C22H24N2O2. Molecular weight 348.44. Reagent Grade Chemicals. |
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Potent CCR1 and CCR3 antagonist Synonyms: 1, 4-TRANS-1- (1-CYCLOOCTEN-1-YLMETHYL) -4-[[ (2, 7-DICHLORO-9H-XANTHEN-9-YL) CARBONYL] AMINO] - 1- ETHYLPIPERIDINIUM IODIDE. Cas No. 301648-08-8. Molecular formula C30H37Cl2IN2O2. Molecular weight 655.44. Laboratory Reagents. |
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UCF 101 is an Omi/HtrA2 protease inhibitor with IC50 value of 9.5 ?M. Omi/HtrA2 is a mitochondria serine protease released in response to apoptotic stimuli. UCF 101 is naturally fluorescent enabling the visualization of its entry into cells. UCF 101 Other Name: RT-014861; 5-({5-[2-(Dihydroxyamino)phenyl]furan-2-yl}methylidene)-1,3-diphenyl-2-sulfanylidenedihydropyrimidine-4,6(1H,5H)-dione. Molecular Formula: C27H17N3O5S. CAS Number: 313649-08-0. Molecular weight 495.5. Categories: Laboratory Reagents Grade. |
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UCL 1684 is a potent and nonpeptidic blocker of the apamin-sensitive Ca2+-activated K+ channel (KCa2. 1) (IC50 = 3 nM in rat sympathetic neurons). UCL 1684 was shown to block hKCa2. 1 and rKCa2. 2 channels expressed in HEK 293 cells (IC50 = 762 and 364 pM, r Synonyms: 6, 12, 19, 20, 25, 26-Hexahydro-5, 27:13, 18:21, 24-trietheno-11, 7-metheno-7H-dibenzo [b, n] [1, 5, 12, 16]tetraazacyclotricosine-5, 13-diium dibromide. Cas No. 199934-16-2. Molecular formula C34H30Br2N4. Molecular weight 654.44. Laboratory Reagents. |
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UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker that reduces sAHP in hippocampal slice preparations. UCL 2077 exhibits no effect on Ca2+ currents or the time course of sAHP/sIAHP. It also inhibits KCNQ1 and KCNQ2. Synonyms: N-Trityl-3-pyridinemethanamine; (3-Triphenylmethylaminomethyl) pyridine. Cas No. 918311-87-2. Molecular formula C25H22N2. Molecular weight 350.46. Laboratory Chemicals. |
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UCLA GP130 2 is a brain-penetrant gp130 agonist, protecting against NMDA-induced toxicity in primary hippocampal neurons in vitro, and increasing STAT3 phosphorylation in SH-SY5Y cells. UCLA GP130 2 Other Name: N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine. Molecular Formula: C15H11FN2S. CAS Number: 339303-87-6. Molecular weight 270.32. Categories: Laboratory Reagents Grade. |
| UCM53 Quick inquiry Where to buy Suppliers range |
UCM53 is an inhibitor of bacterial cell division that binds to the GTP site of the cell division protein FtsZ. It inhibits the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis. UCM53 Other Name: [4-(3-Chloro-4-hydroxybenzoyl)oxynaphthalen-2-yl] 3,4-dihydroxybenzoate. Molecular Formula: C24H15ClO7. CAS Number: 1449468-52-3. Molecular weight 450.8. Categories: Fine Chemicals. |
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UCM 707 is a potent endocannabinoid transport inhibitor (IC50 = 0. 8 and 30 M for inhibition of the anandamide transporter and FAAH, respectively). UCM 707 potentiates hypokinetic and antinociceptive effects of anandamide in vivo. Synonyms: (5Z, 8Z, 11Z, 14Z) -N- (3-Furanylmethyl) -5, 8, 11, 14-eicosatetraenamide; N- (furan-3-ylmethyl) icosa-5, 8, 11, 14-tetraenamide. Cas No. 390824-20-1. Molecular formula C25H37NO2. Molecular weight 383.57. Reagent Grade Laboratory Chemicals. |
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An indolocarbazole isolated from a high staurosporine-producing streptomyces culture as a minor co-metabolite Cas No. 121569-61-7. Molecular formula C28H26N4O4. Molecular weight 482.5. Reagent Grade Chemicals. |
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UCPH 101 is a selective non-substrate inhibitor of EAAT1 (IC50 = 660, >300000 and >300000 nM for EAAT1, EAAT2 and EAAT3, respectively). UCPH 101 selectively inhibits anion currents in tsA201 cells expressing human EAAT1 (Kd = 0. 34 M) over rat EAAT4 and m Synonyms: 2-Amino-5, 6, 7, 8-tetrahydro-4- (4-methoxyphenyl) -7- (naphthalen-1-yl) -5-oxo-4H-chromene-3-carbonitrile. Cas No. 1118460-77-7. Molecular formula C27H22N2O3. Molecular weight 422.48. Fine Chemicals. |
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Udenafil is an oral PDE5 inhibitor. Udenafil significantly increased cAMP and cGMP levels and were more highly distributed in the prostate than plasma. The T/P ratio of udenafil was higher than tadalafil. These findings may help in the assessment of the f Synonyms: DA8159; Zydena. Cas No. 268203-93-6. Molecular formula C25H36N6O4S. Molecular weight 516.66. Reagent Grade Laboratory Chemicals. |
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Udenafil-d7 is the labelled analogue of Udenafil. Udenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: 3- (6, 7- Dihydro- 1- methyl - 7- oxo- 3- propyl- 1H- pyrazolo [ 4, 3-d]pyrimidin-5-yl) -N-[2- (1-methyl-2-pyrrolidinyl) ethyl]-4- (propoxy-d7) benzenesulfonamide; DA 8159-d7; Zydena-d7. Cas No. 1175992-76-3. Molecular formula C25H29N6O4SD7. Molecular weight 523.71. Fine Chemicals. |
| UDP-2, 3-diacetamido-2, 3-dideoxyglucuronic acid 2-epimerase Quick inquiry Where to buy Suppliers range |
This enzyme participates in the biosynthetic pathway for UDP-?-D-ManNAc3NAcA (UDP-2, 3-diacetamido-2, 3-dideoxy-?-D-mannuronic acid), an important precursor of the B-band lipopolysaccharide of Pseudomonas aeroginosa serotype O5 and of the band-A trisaccharide of Bordetella pertussis, both important respiratory pathogens. The enzyme is highly specific as UDP-?-D-GlcNAc, UDP-?-D-GlcNAcA (UDP-2-acetamido-2-deoxy-?-D-glucuronic acid) and UDP-?-D-GlcNAc3NAc (UDP-2, 3-diacetamido-2, 3-dideoxy-?-D-glucose) cannot act as substrates. UDP-2, 3-diacetamido-2, 3-dideoxyglucuronic acid 2-epimerase Group: Enzymes. Alternative Name: UDP-GlcNAc3NAcA 2-epimerase; UDP-?-D-GlcNAc3NAcA 2-epimerase; 2, 3-diacetamido-2, 3-dideoxy-?-D-glucuronic acid 2-epimerase; WbpI; WlbD. Global enzyme suppliers, distributors and manufacturers. |
| UDP-2, 3-diacylglucosamine diphosphatase Quick inquiry Where to buy Suppliers range |
The enzyme catalyses a step in the biosynthesis of lipid A. UDP-2, 3-diacylglucosamine diphosphatase Group: Enzymes. Alternative Name: UDP-2, 3-diacylglucosamine hydrolase; UDP-2, 3-diacylglucosamine pyrophosphatase; ybbF (gene name); lpxH (gene name); UDP-2, 3-bis[(3R)-3-hydroxymyristoyl]-?-D-glucosamine 2, 3-bis[(3R)-3-hydroxymyristoyl]- β -D-glucosaminyl 1-phosphate phosphohydrolase (incorrect). Custom enzymes manufacturing. |
| UDP-2, 4-diacetamido-2, 4, 6-trideoxy-β -L-altropyranose hydrolase Quick inquiry Where to buy Suppliers range |
The enzyme is involved in biosynthesis of pseudaminic acid. UDP-2, 4-diacetamido-2, 4, 6-trideoxy- β -L-altropyranose hydrolase Group: Enzymes. Alternative Name: PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2, 4-bis(acetamido)-2, 4, 6-trideoxy- β -L-altropyranose hydrolase. Enzyme manufacturers USA. |
| UDP-2-acetamido-2, 6-β -L-arabino-hexul-4-ose reductase Quick inquiry Where to buy Suppliers range |
Part of the biosynthesis of UDP-N-acetyl-L-fucosamine. Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. UDP-2-acetamido-2, 6- β -L-arabino-hexul-4-ose reductase Group: Enzymes. Alternative Name: WbjC; Cap5F. Global enzyme suppliers, distributors and manufacturers. |
| UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase Quick inquiry Where to buy Suppliers range |
A pyridoxal 5'-phosphate protein. This enzyme participates in the biosynthetic pathway for UDP-?-D-ManNAc3NAcA (UDP-2, 3-diacetamido-2, 3-dideoxy-?-D-mannuronic acid), an important precursor of B-band lipopolysaccharide. The enzymes from Pseudomonas aeruginosa serotype O5 and Thermus thermophilus form a complex with the previous enzyme in the pathway, EC 1. 1. 1. 335 (UDP-N-acetyl-2-amino-2-deoxyglucuronate oxidase). UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase Group: Enzymes. Alternative Name: WbpE; WlbC. Custom enzymes manufacturing. |
