A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12-61 μM for exposure times of 72 h. There was also no selective inhibition of DNA, RNA or protein synthesis after exposure to UA8967. UA8967 is observed to affect the plasma membrane. Synonyms: UA-8967; UA 8967; 3-[(4-Benzyl-1-piperazinyl)methyl]indole. CAS No. 17511-50-1. Molecular formula: C20H23N3. Mole weight: 305.42.
UAB30
UAB30 is a low-toxicity retinoid X receptor-selective agonist selective for the binding and activation of RXR's over RAR' s. UAB30 is highly effective in the prevention of breast cancers in a rat model. Synonyms: (2E,4E,6Z,8E)-8-(3,4-dihydro-2H-naphthalen-1-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid; (9Z)-UAB30; 8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid; 9-cis-UAB30; 9cUAB30; 9cUAB30, 9-cis UAB30, (all-E)-UAB 30, all-trans-UAB 30, UAB30, UAB-30, UAB 30; 9-cis-UAB30. Grades: >98%. CAS No. 205252-59-1. Molecular formula: C20H22O2. Mole weight: 294.39.
U Acetic acid
A nucleobase for PNA synthesis. Synonyms: (2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetic acid; 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid; (2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid. Grades: 98%. CAS No. 4113-97-7. Molecular formula: C6H6N2O4. Mole weight: 170.12.
UAMC 00039 dihydrochloride
UAMC 00039 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 697797-51-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UAMC00039 dihydrochloride
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor (IC50 = 0.48 nM) with selectivity against DPP-9, DPP-8 and DPP-IV (IC50= 78.6, 142 and 165 μM, respectively). Synonyms: UAMC00039, UAMC 00039, UAMC-00039, UAMC 00039 dihydrochloride, UAMC 00039 2HCl; (2S)-2-amino-4-[(4-chlorophenyl)methylamino]-1-piperidin-1-ylbutan-1-one;dihydrochloride; N-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butane-diamine hydrochloride. CAS No. 697797-51-6. Molecular formula: C16H26Cl3N3O. Mole weight: 382.76.
UAMC-3203
UAMC-3203 is a ferroptosis inhibitor with IC50 value of 10 nM. Synonyms: UAMC 3203; UAMC3203; 3-(Benzylamino)-4-(cyclohexylamino)-N-(2-piperazin-1-ylethyl)benzenesulfonamide. CAS No. 2271358-64-4. Molecular formula: C25H37N5O2S. Mole weight: 471.66.
UAU
UAU (UpApU) is a trinucleotide that is identified as the RNA codon for tyrosine, which is involved in protein synthesis. UAU can be used in research about the interaction between RNA codons, tRNAs, and ribosomes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UpApU. CAS No. 752-71-6. Pack Sizes: 1 mg. Product ID: HY-159807.
UB 165 fumarate
UB 165 fumarate is a full agonist at α3β2- and a weak partial agonist at α4β2- containing nAChRs (Ki = 0.27, 20 (IC50), 2790 and 990 nM for α4β2, α3, α7 and α1β1δε, respectively). Synonyms: UB 165 fumarate; UB165 fumarate; UB-165 fumarate; 2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene fumarate. Grades: ≥99% by HPLC. CAS No. 200432-86-6. Molecular formula: C13H15ClN2.C4H4O4. Mole weight: 350.8.
Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN4018. CAS No. 2305629-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99539.
UbcH13 Inhibitor, NSC697923 - CAS 343351-67-8
The UbcH13 Inhibitor, NSC697923 controls the biological activity of UbcH13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
UbcH13 (UBE2N) Active human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
UbcH1 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
UbcH5a human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
UbcH5b human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
UbcH6 (UBE2E1) Active human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
UbcH9 Conjugating Enzyme human
?95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24N2O4. CAS No. 58970-76-6. Prepack ID 89989951-250mg. Molecular Weight 308.37. See USA prepack pricing.
Ubenimex
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin;nk421;UBENIMEX;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-LEU. Appearance: White crystalline powder. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37. Purity: 0.99. IUPACName: (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoicacid. Canonical SMILES: CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O. Density: 1.197 g/
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ubiquicidin
Ubiquicidin is a synthetic cationic antimicrobial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Val-His-Gly-Ser-Leu-Ala-Arg-Ala-Gly-Lys-Val-Arg-Gly-Gln-Thr-Pro-Lys-Val-Ala-Lys-Gln-Glu-Lys-Lys-Lys-Lys-Lys-Thr-Gly-Arg-Ala-Lys-Arg-Arg-Met-Gln-Tyr-Asn-Arg-Arg-Phe-Val-Asn-Val-Val-Pro-Thr-Phe-Gly-Lys-Lys-Lys-Gly-Pro-Asn-Ala-Asn-Ser. Mole weight: 6648.
Ubiquinol
A reduced coenzyme Q for improving nervous system cell functions. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl -2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl- 1,4-benzenediol; Dihydrocoenzyme Q10; Reduced Coenzyme Q10; Reduced Ubiquinone Q10; Ubiquinol 50. CAS No. 992-78-9. Molecular formula: C59H92O4. Mole weight: 865.37.
Ubiquinol
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
ubiquinol oxidase (electrogenic, non H+-transporting)
This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1. The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 1.10.3.10, ubiquinol oxidase (H+-transporting). Group: Enzymes. Synonyms: cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Enzyme Commission Number: EC 7.1.1.7 (Formerly EC 1.10.3.14). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0480; ubiquinol oxidase (electrogenic, non H+-transporting); EC 1.10.3.14; cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Cat No: EXWM-0480.
ubiquinol oxidase (H+-transporting)
Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo3 oxidase it is 2, while for the bd-II oxidase it is 1. cf. EC 1.10.3.14, ubiquinol oxidase (electrogenic, non H+-transporting). Group: Enzymes. Synonyms: cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Enzyme Commission Number: EC 7.1.1.3 (Formerly EC 1.10.3.10). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0476; ubiquinol oxidase (H+-transporting); EC 1.10.3.10; cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Cat No: EXWM-0476.
ubiquinol oxidase (non-electrogenic)
The enzyme, described from the mitochondria of plants and some fungi and protists, is an alternative terminal oxidase that is not sensitive to cyanide inhibition and does not generate a proton motive force. Unlike the electrogenic terminal oxidases that contain hemes (cf. EC 1.10.3.10 and EC 1.10.3.14), this enzyme contains a dinuclear non-heme iron complex. The function of this oxidase is believed to be dissipating excess reducing power, minimizing oxidative stress, and optimizing photosynthesis in response to changing conditions. Group: Enzymes. Synonyms: plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Enzyme Commission Number: EC 1.10.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0477; ubiquinol oxidase (non-electrogenic); EC 1.10.3.11; plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Cat No: EXWM-0477.
Ubiquinone-10
Ubiquinone-10 acts as an inhibitor of the mitochondrial permeability transition pore (MPTP). This inhibitory effect can be counteracted by ubiquinone-5. Applications: An inhibitor of the mitochondrial permeability transition pore. Group: Coenzymes. Synonyms: Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone. CAS No. 606-06-4. Purity: ≥90%. Mole weight: 318.4. Form: Liquid. Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone; Ubiquinone-10; 606-06-4. Cat No: COEC-062.
Ubiquinone-5
Ubiquinone-5 is a coenzyme Q10 (CoQ10) (sc-205262) analog that counteracts the inhibitory effects on mitochondrial permeability transition pore (MPTP) of decylubiquinone and ubiquinone-10. Applications: A coq10 analog that counteracts the inhibitory effects on mptp. Group: Coenzymes. Synonyms: Coenzyme Q1. CAS No. 727-81-1. Mole weight: 250.29. Form: Liquid. Coenzyme Q1; Ubiquinone-5; 727-81-1. Cat No: COEC-012.
Ubiquitin-13C,15N,D human
?98 atom %, ?90% (CP), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-13C,15N human
?98 atom %, ?90% (CP), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-15N,D human
97 atom % D, 98 atom % 15N, recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-15N human
98 atom % 15N, recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-7-amido-4-methylcoumarin
solution (supplied in DMSO). Group: Fluorescence/luminescence spectroscopy.
Ubiquitin Activating Enzyme (E1) human
recombinant, expressed in baculovirus infected Sf21 cells. Group: Fluorescence/luminescence spectroscopy.
Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin Aldehyde human
recombinant, expressed in E. coli, ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Ubiquitination Compound Library
A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening?- Targets include proteasome, E1/E2/E3 Enzyme, DUB, p97, etc. ; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8600. Categories: Ubiquitination Compounds Libraries.
Ubiquitin-Carrier Protein H10 human
?95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin Carrier Protein H3/CDC34 human
?95% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain. Group: Fluorescence/luminescence spectroscopy.
?95% (SDS-PAGE), recombinant, expressed in E. coli (GST-tagged), solution. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-Carrier Protein H7 human
?95% (SDS-PAGE), recombinant, expressed in E. coli, liquid. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin E1 Inhibitor, PYR-41
The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin Isopeptidase Inhibitor I, G5, a cell-permeable cross-conjugated unsaturated dienone compound, is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. Synonyms: NSC-144303; NSC144303; NSC 144303; G5. 3,5-bis[(4-nitrophenyl)methylidene]-1,1-dioxothian-4-one. CAS No. 108477-18-5. Molecular formula: C19H14N2O7S. Mole weight: 414.39.
Ubiquitin Isopeptidase Inhibitor I, G5 - CAS 108477-18-5
The Ubiquitin Isopeptidase Inhibitor I, G5, also referenced under CAS 108477-18-5, controls the biological activity of Ubiquitin Isopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-Specific Protease 10 human
recombinant, expressed in Sf9 cells, ?56% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-Specific Protease 14 human
recombinant, expressed in Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-Specific Protease 5 human
recombinant, expressed in Sf9 cells, ?51% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Ubiquitin-Specific Protease 8 human
recombinant, expressed in Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
ubiquitinyl hydrolase 1
Links to polypeptides smaller than 60 residues are hydrolysed more readily than those to larger polypeptides. Isoforms exist with quantitatively different specificities, amongst the best known being UCH-L1 and UCH-L3, which are major proteins of the brain of mammals. Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde). Ubiquitinyl hydrolase 1 is the type example of peptidase family C12, with a similar protein fold to papain and catalytic amino acids Cys, His and Asp. There is a separate family (C19) of enzymes that also hydrolyse ubiquitinyl bonds, and it is thought that all the ubiquitinyl hydrolases are also ubiquitin thiolesterases (EC 3.1.2.15). Group: Enzymes. Synonyms: ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Enzyme Commission Number: EC 3.4.19.12. CAS No. 86480-67-3, 189642-63-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4084; ubiquitinyl hydrolase 1; EC 3.4.19.12; 86480-67-3, 189642-63-5; ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Cat No: EXWM-4084.
Ublituximab
Ublituximab (LFB-R603; TG-1101; TGTX-1101) is a next-generation, type 1 chimeric monoclonal antibody targeting a unique epitope on the CD20 antigen. Ublituximab has anticancer effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LFB-R603; TG-1101; TGTX-1101. CAS No. 1174014-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99538.
UBP1112
UBP1112. Group: Biochemicals. Grades: Purified. CAS No. 339526-74-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UBP1112
UBP1112 is a selective group III mGlu receptor antagonist (apparent Kd=5.1 and 488 μM for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors). Synonyms: UBP1112; UBP 1112; UBP-1112; α-Methyl-3-methyl-4-phosphonophenylglycine; 2-amino-2-(3-methyl-4-phosphonophenyl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 339526-74-8. Molecular formula: C10H14NO5P. Mole weight: 259.2.
UBP 282
UBP 282. Group: Biochemicals. Grades: Purified. CAS No. 544697-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UBP 282
UBP 282 is an AMPA and kainate receptor antagonist. UBP 282 inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres. Synonyms: UBP-282, UBP 282, UBP282; (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; VBP. Grades: ≥98% by HPLC. CAS No. 544697-47-4. Molecular formula: C15H15N3O6. Mole weight: 333.3.
UBP 296
UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1.09 μM) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. It has no activity at NMDA or group I mGlu receptors. UBP 296 was shown to selectively block kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Synonyms: UBP 296; UBP296; UBP-296; (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione; 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 745055-86-1. Molecular formula: C15H15N3O6. Mole weight: 333.3.
UBP 296
UBP 296. Group: Biochemicals. Grades: Purified. CAS No. 745055-86-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UBP 301
UBP 301 is a potent kainate receptor antagonist (apparent Kd = 5.94 μM), displaying ~ 30-fold selectivity over AMPA receptors. Synonyms: UBP 301; UBP301; UBP-301; (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; 4-[[3-[(2S)-2-amino-2-carboxyethyl]-5-iodo-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 569371-10-4. Molecular formula: C15H14IN3O6. Mole weight: 459.2.
UBP 301
UBP 301. Group: Biochemicals. Grades: Purified. CAS No. 569371-10-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.