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| Product | Description | |
|---|---|---|
| UB 165 fumarate | UB 165 fumarate is a full agonist at α3β2- and a weak partial agonist at α4β2- containing nAChRs (Ki = 0.27, 20 (IC50), 2790 and 990 nM for α4β2, α3, α7 and α1β1δε, respectively). Synonyms: UB 165 fumarate; UB165 fumarate; UB-165 fumarate; 2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene fumarate. Grades: ≥99% by HPLC. CAS No. 200432-86-6. Molecular formula: C13H15ClN2.C4H4O4. Mole weight: 350.8. |  |
| Ubamatamab | Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN4018. CAS No. 2305629-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99539. |  |
| Ubenimex | 250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24N2O4. CAS No. 58970-76-6. Prepack ID 89989951-250mg. Molecular Weight 308.37. See USA prepack pricing. |  |
| Ubenimex | Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds. Alternative Names: 3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin;nk421;UBENIMEX;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-LEU. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37. Appearance: White crystalline powder. Purity: 0.99. IUPACName: (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoicacid. Canonical SMILES: CC (C)CC (C (=O)O)NC (=O)C (C (CC1=CC=CC=C1)N)O. Density: 1.197 g/cm³. ECNumber: 261-529-2. Catalog: ACM58970766. |  |
| UBE Polyethylene | UBE Polyethylene. Group: Polymers. |  |
| Ubiquicidin | Ubiquicidin is a synthetic cationic antimicrobial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Val-His-Gly-Ser-Leu-Ala-Arg-Ala-Gly-Lys-Val-Arg-Gly-Gln-Thr-Pro-Lys-Val-Ala-Lys-Gln-Glu-Lys-Lys-Lys-Lys-Lys-Thr-Gly-Arg-Ala-Lys-Arg-Arg-Met-Gln-Tyr-Asn-Arg-Arg-Phe-Val-Asn-Val-Val-Pro-Thr-Phe-Gly-Lys-Lys-Lys-Gly-Pro-Asn-Ala-Asn-Ser. Mole weight: 6648. | |
| Ubiquinol | A reduced coenzyme Q for improving nervous system cell functions. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl -2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl- 1,4-benzenediol; Dihydrocoenzyme Q10; Reduced Coenzyme Q10; Reduced Ubiquinone Q10; Ubiquinol 50. CAS No. 992-78-9. Molecular formula: C59H92O4. Mole weight: 865.37. | |
| Ubiquinol | Ubiquinol. CAS No: 992-78-9 |  Sarchem Laboratories New Jersey NJ |
| Ubiquinol | Reduced coenzyme Q for improving nervous system cell functions. Group: Biochemicals. Alternative Names: 2-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E, 34E)-3, 7, 11, 15, 19, 23, 27, 31, 35, 39-Decamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34, 38-tetracontadecaen-1-yl]-5, 6-dimethoxy-3-methyl- 1,4-benzenediol; Dihydrocoenzyme Q10; Reduced Coenzyme Q10; Reduced Ubiquinone Q10; Ubiquinol 50. Grades: Highly Purified. CAS No. 992-78-9. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| ubiquinol oxidase (electrogenic, non H+-transporting) | This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1. The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 1.10.3.10, ubiquinol oxidase (H+-transporting). Group: Enzymes. Synonyms: cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Enzyme Commission Number: EC 7.1.1.7 (Formerly EC 1.10.3.14). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0480; ubiquinol oxidase (electrogenic, non H+-transporting); EC 1.10.3.14; cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Cat No: EXWM-0480. |  |
| ubiquinol oxidase (H+-transporting) | Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo3 oxidase it is 2, while for the bd-II oxidase it is 1. cf. EC 1.10.3.14, ubiquinol oxidase (electrogenic, non H+-transporting). Group: Enzymes. Synonyms: cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Enzyme Commission Number: EC 7.1.1.3 (Formerly EC 1.10.3.10). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0476; ubiquinol oxidase (H+-transporting); EC 1.10.3.10; cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Cat No: EXWM-0476. | |
| ubiquinol oxidase (non-electrogenic) | The enzyme, described from the mitochondria of plants and some fungi and protists, is an alternative terminal oxidase that is not sensitive to cyanide inhibition and does not generate a proton motive force. Unlike the electrogenic terminal oxidases that contain hemes (cf. EC 1.10.3.10 and EC 1.10.3.14), this enzyme contains a dinuclear non-heme iron complex. The function of this oxidase is believed to be dissipating excess reducing power, minimizing oxidative stress, and optimizing photosynthesis in response to changing conditions. Group: Enzymes. Synonyms: plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Enzyme Commission Number: EC 1.10.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0477; ubiquinol oxidase (non-electrogenic); EC 1.10.3.11; plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Cat No: EXWM-0477. | |
| Ubiquinone | Heterocyclic Organic Compound. CAS No. 10303-98-0. Purity: 0.96. Catalog: ACM10303980. | |
| Ubiquinone-10 | Ubiquinone-10 acts as an inhibitor of the mitochondrial permeability transition pore (MPTP). This inhibitory effect can be counteracted by ubiquinone-5. Applications: An inhibitor of the mitochondrial permeability transition pore. Group: Coenzymes. Synonyms: Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone. CAS No. 606-06-4. Purity: ≥90%. Mole weight: 318.4. Form: Liquid. Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone; Ubiquinone-10; 606-06-4. Cat No: COEC-062. | |
| Ubiquinone-5 | Ubiquinone-5 is a coenzyme Q10 (CoQ10) (sc-205262) analog that counteracts the inhibitory effects on mitochondrial permeability transition pore (MPTP) of decylubiquinone and ubiquinone-10. Applications: A coq10 analog that counteracts the inhibitory effects on mptp. Group: Coenzymes. Synonyms: Coenzyme Q1. CAS No. 727-81-1. Mole weight: 250.29. Form: Liquid. Coenzyme Q1; Ubiquinone-5; 727-81-1. Cat No: COEC-012. | |
| Ubiquitination Compound Library | A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening?- Targets include proteasome, E1/E2/E3 Enzyme, DUB, p97, etc. ; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8600. Categories: Ubiquitination Compounds Libraries. |  |
| Ubiquitin Isopeptidase Inhibitor I, G5 | Ubiquitin Isopeptidase Inhibitor I, G5, a cell-permeable cross-conjugated unsaturated dienone compound, is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. Synonyms: NSC-144303; NSC144303; NSC 144303; G5. 3,5-bis[(4-nitrophenyl)methylidene]-1,1-dioxothian-4-one. CAS No. 108477-18-5. Molecular formula: C19H14N2O7S. Mole weight: 414.39. | |
| ubiquitinyl hydrolase 1 | Links to polypeptides smaller than 60 residues are hydrolysed more readily than those to larger polypeptides. Isoforms exist with quantitatively different specificities, amongst the best known being UCH-L1 and UCH-L3, which are major proteins of the brain of mammals. Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde). Ubiquitinyl hydrolase 1 is the type example of peptidase family C12, with a similar protein fold to papain and catalytic amino acids Cys, His and Asp. There is a separate family (C19) of enzymes that also hydrolyse ubiquitinyl bonds, and it is thought that all the ubiquitinyl hydrolases are also ubiquitin thiolesterases (EC 3.1.2.15). Group: Enzymes. Synonyms: ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Enzyme Commission Number: EC 3.4.19.12. CAS No. 86480-67-3, 189642-63-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4084; ubiquitinyl hydrolase 1; EC 3.4.19.12; 86480-67-3, 189642-63-5; ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Cat No: EXWM-4084. | |
| Ublituximab | Ublituximab (LFB-R603; TG-1101; TGTX-1101) is a next-generation, type 1 chimeric monoclonal antibody targeting a unique epitope on the CD20 antigen. Ublituximab has anticancer effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LFB-R603; TG-1101; TGTX-1101. CAS No. 1174014-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99538. | |
| UBP1112 | UBP1112. Group: Biochemicals. Grades: Purified. CAS No. 339526-74-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP1112 | UBP1112 is a selective group III mGlu receptor antagonist (apparent Kd=5.1 and 488 μM for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors). Synonyms: UBP1112; UBP 1112; UBP-1112; α-Methyl-3-methyl-4-phosphonophenylglycine; 2-amino-2-(3-methyl-4-phosphonophenyl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 339526-74-8. Molecular formula: C10H14NO5P. Mole weight: 259.2. | |
| UBP 282 | UBP 282 is an AMPA and kainate receptor antagonist. UBP 282 inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres. Synonyms: UBP-282, UBP 282, UBP282; (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; VBP. Grades: ≥98% by HPLC. CAS No. 544697-47-4. Molecular formula: C15H15N3O6. Mole weight: 333.3. | |
| UBP 282 | UBP 282. Group: Biochemicals. Grades: Purified. CAS No. 544697-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP 296 | UBP 296. Group: Biochemicals. Grades: Purified. CAS No. 745055-86-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP 296 | UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1.09 μM) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. It has no activity at NMDA or group I mGlu receptors. UBP 296 was shown to selectively block kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Synonyms: UBP 296; UBP296; UBP-296; (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione; 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 745055-86-1. Molecular formula: C15H15N3O6. Mole weight: 333.3. | |
| UBP 301 | UBP 301 is a potent kainate receptor antagonist (apparent Kd = 5.94 μM), displaying ~ 30-fold selectivity over AMPA receptors. Synonyms: UBP 301; UBP301; UBP-301; (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; 4-[[3-[(2S)-2-amino-2-carboxyethyl]-5-iodo-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 569371-10-4. Molecular formula: C15H14IN3O6. Mole weight: 459.2. | |
| UBP 301 | UBP 301. Group: Biochemicals. Grades: Purified. CAS No. 569371-10-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP 302 | UBP 302. Group: Biochemicals. Grades: Purified. CAS No. 745055-91-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP 302 | UBP 302 is a potent and selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 402 nM) that displays ~ 260-fold selectivity over AMPA receptors, ~ 90-fold selectivity over recombinant human GLUK6- and GLUK2-containing kainate receptors. It has no activity at NMDA or group I mGlu receptors. UBP 302 was shown to block kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Synonyms: UBP302, UBP-302, UBP 302; (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione; 2-[[3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 745055-91-8. Molecular formula: C15H15N3O6. Mole weight: 333.3. | |
| UBP 310 | UBP 310 is a GLUK5 kainate receptor antagonist (IC50 = 130 nM), displaying 12,700-fold selectivity for GLUK5 over GLUK6. It has no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. UBP 310 also blocks recombinant homomeric GLUK7 receptors. Synonyms: UBP310, UBP 310, UBP-310; (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione; 3-[[3-(2-amino-2-carboxyethyl)-5-methylidene-2,6-dioxopyrimidin-3-ium-1-yl]methyl]thiophene-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 902464-46-4. Molecular formula: C14H15N3O6S. Mole weight: 353.35. | |
| UBP 310 | UBP 310. Group: Biochemicals. Grades: Purified. CAS No. 902464-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UBP310 (GluK1/GluK3 Antagonist, UBP310, (S)-1-(2-Amino-2-carboxyethyl)-3-(2Â-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidineÂ-2,4-dione, UBP-310, UBP 310) | A potent antagonist highly selective for GluK1 (Kb = 10nM), GluK3 (IC50 = 23nM), and GluK1/K5 (Kb = 8nM) subtype kainate receptors. Does not interact with GluK2 and GluK2/K5 receptors. Low affinity to AMPA receptors (Kd = 83uM). Does not interact with mGluR1 ornMDA receptors at concentration less than 10uM. Often used in studying neuronal excitability and synaptic plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 902464-46-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ubrogepant | Ubrogepant is and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist originated by Merck & Co. In Sep 2016, Allergan initiated a phase III extension trial for Migraine in USA. Uses: Migraine. Synonyms: MK-1602; MK 1602; MK1602; Ubrogepant; (3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxo-spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide. Grades: 98%. CAS No. 1374248-77-7. Molecular formula: C29H26F3N5O3. Mole weight: 549.55. | |
| Ubrogepant | Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor ( CGRP ). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-1602. CAS No. 1374248-77-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12366. | |
| UBX domain-containing protein 11 (447-460) | UBX domain-containing protein 11 (447-460) is a peptide derived from UBX domain-containing protein 11. UBX domain-containing protein 11 is involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. It promotes RHOA activation mediated by GNA12 and GNA13. Synonyms: Colorectal tumor-associated antigen COA-1 (447-460); UBX domain-containing protein 5 (447-460). | |
| UC 112 | UC-112 is an IAP inhibitor (IC50 values from 0.7 - 3.4 μM). UC-112 also potently inhibits the growth of P-glycoprotein. Uses: Iap inhibitor. Synonyms: UC-112; UC 112; UC112; 5-((benzyloxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol; (Z,6R)-2-methyl-6-[(5R,9R,10R,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-enoic acid. Grades: ≥98%. CAS No. 383392-66-3. Molecular formula: C22H24N2O2. Mole weight: 348.44. | |
| UC 112 | UC 112. Group: Biochemicals. Grades: Purified. CAS No. 383392-66-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UCA 1064-A | UCA 1064-A is an antitumor antibiotic isolated from Wallemia sebi, which inhibits HeLa S3 cells with IC50 of 12.7 μmol/L, suppresses saccharomyces cerevisiae and gram-positive bacteria with MIC of 0.05 and 40 μg/mL, respectively. Molecular formula: C28H45NO. Mole weight: 411.66. | |
| UCA 1064-B | UCA 1064-B is an antitumor antibiotic isolated from Wallemia sebi, which inhibits HeLa S3 cells with IC50 of 14.8 μmol/L, suppresses saccharomyces cerevisiae and gram-positive bacteria with MIC of 0.39 and 40 μg/mL, respectively. Molecular formula: C28H47NO. Mole weight: 413.68. | |
| Ucar Solution Vinyl Resin 9003-22-9 | Ucar Solution Vinyl Resin - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| UCB 35625 | UCB 35625. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| UCB 35625 | UCB 35625 is a potent CCR1 and CCR3 antagonist. Synonyms: UCB35625, UCB 35625, UCB-35625; 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE. CAS No. 301648-08-8. Molecular formula: C30H37Cl2IN2O2. Mole weight: 655.44. | |
| UCE1022 | UCE1022 is a cytotoxin with topoisomerase I mediated DNA cleavage activity. Synonyms: UCE-1022; UCE 1022. CAS No. 158243-10-8. Molecular formula: C18H10O10S. Mole weight: 418.3. | |
| UCE 6 | UCE 6 is an antitumor metabolite with topoisomerase I mediated DNA cleavage activity. Synonyms: UCE-6; UCE6. CAS No. 150829-94-0. Molecular formula: C24H20O8. Mole weight: 436.4. | |
| Ucenprubart | Ucenprubart is an anti- CD200R1 human IgG4κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2414559-57-0. Pack Sizes: 1 mg. Product ID: HY-P990770. | |
| Ucf-101 | Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2 , with an IC 50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC 50 >200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 313649-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125959. | |
| UCF 101 | UCF 101 is an Omi/HtrA2 protease inhibitor with IC50 value of 9.5 μM. Omi/HtrA2 is a mitochondria serine protease released in response to apoptotic stimuli. UCF 101 is naturally fluorescent enabling the visualization of its entry into cells. Synonyms: RT-014861; 5-({5-[2-(Dihydroxyamino)phenyl]furan-2-yl}methylidene)-1,3-diphenyl-2-sulfanylidenedihydropyrimidine-4,6(1H,5H)-dione. Grades: ≥98%. CAS No. 313649-08-0. Molecular formula: C27H17N3O5S. Mole weight: 495.5. | |
| UCF116-A | UCF116-A is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C37H48N2O8. Mole weight: 648.78. | |
| UCF116-B | UCF116-B is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C36H48N2O8. Mole weight: 636.77. | |
| UCF116-C | UCF116-C is a metabolite produced by Steptomyces sp. It is inactive for Ftase. Molecular formula: C34H46N2O8. Mole weight: 610.74. | |
| UCF76-A | UCF76-A is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C19H20O7. Mole weight: 360.36. | |
| UCF76-B | UCF76-B is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C18H16O7. Mole weight: 344.31. | |
| UCF76-C | UCF76-C is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C18H16O6. Mole weight: 328.32. | |
| UCH9 | UCH9 is an antitumor antibiotic produced Streptomyces. II. It exhibits bacteriophage and gram-positive bacteria activity. Synonyms: UCH-9; UCH 9. Molecular formula: C55H82O24. Mole weight: 1127.2. | |
| UCL 1684 | UCL 1684 is a potent and nonpeptidic blocker of the apamin-sensitive Ca2+-activated K+ channel (KCa2.1) (IC50 = 3 nM in rat sympathetic neurons). UCL 1684 was shown to block hKCa2.1 and rKCa2.2 channels expressed in HEK 293 cells (IC50 = 762 and 364 pM, respectively). Synonyms: UCL-1684 Dibromide; UCL 1684 Dibromide; UCL1684 Dibromide; UCL-1684 Br; UCL 1684 Br; UCL1684 Br; 6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo [b,n] [1,5,12,16]tetraazacyclotricosine-5,13-diium dibromide. Grades: ≥97% by HPLC. CAS No. 199934-16-2. Molecular formula: C34H30Br2N4. Mole weight: 654.44. | |
| UCL 2077 | UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker that reduces sAHP in hippocampal slice preparations. UCL 2077 exhibits no effect on Ca2+ currents or the time course of sAHP/sIAHP. It also inhibits KCNQ1 and KCNQ2. Synonyms: UCL2077, UCL 2077, UCL-2077; N-Trityl-3-pyridinemethanamine; (3-Triphenylmethylaminomethyl)pyridine. Grades: ≥99% by HPLC. CAS No. 918311-87-2. Molecular formula: C25H22N2. Mole weight: 350.46. | |
| UCL 2077 | UCL 2077. Group: Biochemicals. Grades: Purified. CAS No. 918311-87-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UCLA GP130 2 | UCLA GP130 2 is a brain-penetrant gp130 agonist, protecting against NMDA-induced toxicity in primary hippocampal neurons in vitro, and increasing STAT3 phosphorylation in SH-SY5Y cells. Synonyms: N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine. Grades: ≥98% by HPLC. CAS No. 339303-87-6. Molecular formula: C15H11FN2S. Mole weight: 270.32. | |
| UCM53 | UCM53 is an inhibitor of bacterial cell division that binds to the GTP site of the cell division protein FtsZ. It inhibits the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis. Synonyms: [4-(3-Chloro-4-hydroxybenzoyl)oxynaphthalen-2-yl] 3,4-dihydroxybenzoate. Grades: ≥98%. CAS No. 1449468-52-3. Molecular formula: C24H15ClO7. Mole weight: 450.8. | |
| UCM 707 | UCM 707. Group: Biochemicals. Grades: Purified. CAS No. 390824-20-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UCM 707 | UCM 707 is a potent endocannabinoid transport inhibitor (IC50 = 0.8 and 30 μM for inhibition of the anandamide transporter and FAAH, respectively). UCM 707 potentiates hypokinetic and antinociceptive effects of anandamide in vivo. Synonyms: UCM 707; UCM707; UCM-707; (5Z,8Z,11Z,14Z)-N-(3-Furanylmethyl)-5,8,11,14-eicosatetraenamide; N-(furan-3-ylmethyl)icosa-5,8,11,14-tetraenamide. CAS No. 390824-20-1. Molecular formula: C25H37NO2. Mole weight: 383.57. | |
| UCN-01 | KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Synonyms: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grades: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
| Ucn-02 | Heterocyclic Organic Compound. CAS No. 121569-61-7. Molecular formula: C28H26N4O4. Mole weight: 482.5. Appearance: Pale yellow solid. Purity: >98%. Canonical SMILES: CC12C (C (CC (O1)N3C4=CC=CC=C4C5=C6C (=C7C8=CC=CC=C8N2C7=C53)C (NC6=O)O)NC)OC. Catalog: ACM121569617. | |
| UCN-02 | UCN-02 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. Synonyms: Antibiotic UCN 02; UCN02; GNF-Pf-3072; 7-hydroxy-staurosporine; 7-epi-Hydroxystaurosporine; (3S,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; [3S-(3α, 9α, 10β, 11β, 13α)]-2, 3, 10, 11, 12, 13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9, 13-epoxy-1H, 9H-diindolo[1, 2, 3-gh:3', 2', 1'-lm]pyrrolo[3, 4-j][1, 7]benzodiazonin-1-one. Grades: >95% by HPLC. CAS No. 121569-61-7. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
| Ucph 101 | Heterocyclic Organic Compound. Alternative Names: UCPH 101. CAS No. 1118460-77-7. Molecular formula: C27H22N2O3. Mole weight: C27H22N2O3. Purity: >98 %. IUPACName: 2-amino-4-(4-methoxyphenyl)-7-naphthalen-1-yl-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile. Canonical SMILES: COC1=CC=C (C=C1)C2C (=C (OC3=C2C (=O)CC (C3)C4=CC=CC5=CC=CC=C54)N)C#N. Catalog: ACM1118460777. | |
| UCPH 101 | UCPH 101 is a selective non-substrate inhibitor of EAAT1 (IC50 = 660, >300000 and >300000 nM for EAAT1, EAAT2 and EAAT3, respectively). UCPH 101 selectively inhibits anion currents in tsA201 cells expressing human EAAT1 (Kd = 0.34 μM) over rat EAAT4 and mouse EAAT5 at concentrations up to 10 μM. Synonyms: UCPH-101, UCPH 101, UCPH101; 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile. Grades: ≥98% by HPLC. CAS No. 1118460-77-7. Molecular formula: C27H22N2O3. Mole weight: 422.48. | |
| UCS1025 A | UCS1025 A is an antitumor antibiotic isolated from Acremonium sp. KY4917. It exhibits activity against gram-positive bacteria including Staphylococcus and Enterococcus, and proteusbacillus vulgaris. It also inhibits cell proliferation. Synonyms: UCS 1025A. Molecular formula: C22H29NO5. Mole weight: 387.47. | |
| UCS1025 B | UCS1025 B is an antitumor antibiotic isolated from Acremonium sp. KY4917. It exhibits activity against gram-positive bacteria including Staphylococcus and Enterococcus, and proteusbacillus vulgaris. It also inhibits cell proliferation. The activity of B is much weaker than that of A. Synonyms: UCS 1025B. Molecular formula: C22H29NO6. Mole weight: 403.47. | |
| UCT 1072M1 | UCT 1072M1 is a topoisomerase II poison isolated from Aspergillus sp. KY4919, which is toxic to HeLa S3 and Lu-65 cells. Synonyms: UCT1072M1; UCT-1072M1. Molecular formula: C18H12O8. Mole weight: 356.28. | |
| UCT 1072M2 | UCT 1072M2 is a topoisomerase II poison isolated from Aspergillus sp. KY4919, which is toxic to HeLa S3 and Lu-65 cells. Synonyms: UCT1072M2; UCT-1072M2. Molecular formula: C20H16O7. Mole weight: 368.34. | |
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