A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An isomer of Ulipristal Acetate. Ulipristal Acetate is a selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. Synonyms: (8S,11S,13S,14S,17R)-17-acetyl-11-(4-(dimethylamino)phenyl)-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate. Molecular formula: C30H37NO4. Mole weight: 475.63.
Ulixertinib
Ulixertinib, also known as VRT752271, is an inhibitor of ERK protein kinase. Synonyms: (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib. Grades: 98%. CAS No. 869886-67-9. Molecular formula: C21H22Cl2N4O2. Mole weight: 433.333.
Ulixertinib HCl
Ulixertinib, also known as BVD-523 and VRT752271 is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. Synonyms: (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib hydrochloride. CAS No. 1956366-10-1. Molecular formula: C21H23Cl3N4O2. Mole weight: 469.79.
ULK-101
ULK-101 is a potent and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively. It suppresses autophagy and sensitizes cancer cells to nutrient stress. Synonyms: ULK 101; ULK101; N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-[6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide. CAS No. 2443816-45-1. Molecular formula: C22H16F4N4OS. Mole weight: 460.45.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. Group: Inhibitors. Alternative Names: BCX4208, BCX 4208, BCX-4208, Ulodesine, DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. Appearance: Solid powder. Purity: >98%. IUPACName: 7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one. Canonical SMILES: O=C1C (NC=C2CN3C[C@H] (O)[C@@H] (CO)C3)=C2N=CN1. Catalog: ACM548486595.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. (last update: ). Synonyms: BCX4208; BCX 4208; BCX-4208; DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28.
Ulp1 peptidase
The enzyme from Saccharomyces cerevisiae can also recognize small ubiquitin-like modifier 1 (SUMO-1) from human as a substrate in both SUMO-processing (α-linked peptide bonds) and SUMO-deconjugation (ε-linked peptide bonds) reactions. Ulp1 has several functions, including an essential role in chromosomal segregation and progression of the cell cycle through the G2/M phase of the cell cycle. Belongs in peptidase family C48. Group: Enzymes. Synonyms: Smt3-protein conjugate proteinase; Ubl-specific protease 1; Ulp1; Ulp1 endopeptidase; Ulp1 protease. Enzyme Commission Number: EC 3.4.22.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4244; Ulp1 peptidase; EC 3.4.22.68; Smt3-protein conjugate proteinase; Ubl-specific protease 1; Ulp1; Ulp1 endopeptidase; Ulp1 protease. Cat No: EXWM-4244.
Ultra Dispersed Diamond - P-L
Ultra Dispersed Diamond - P-L. Group: Elements nanoparticles. >96%.
Ultra Dispersed Diamond Powder-DC
Ultra Dispersed Diamond Powder-DC. Group: Elements nanoparticles. >98.5%.
Ultra Dispersed Diamond Powder - P
Ultra Dispersed Diamond Powder - P. Group: Elements nanoparticles. 97%+.
Ultra Dispersed Diamond - WC-DC
Ultra Dispersed Diamond - WC-DC. Group: Elements nanoparticles. >98.5%.
Ultra Dispersed Diamond - WS
Ultra Dispersed Diamond - WS. Group: Elements nanoparticles. >98.5%.
UHMW-PE is a fine material with spherical particles for use in coatings, lubricants, and polyolefin and polyamide compounding. This material contributes to improved dispersion when mixed with other fillers, and adds improved lubrication, scratch and impact resistance to the final polymeric compound. Uses: Fiber, medical, building & construction, automotive. Group: other plastics.
Ultramark1621
Heterocyclic Organic Compound. Alternative Names: SPECTRASYNQ 1621; Hexakis(deuteromethyl)phosphazene. CAS No. 105809-15-2. Molecular formula: C6H12D6N3P3. Mole weight: 231.188. Purity: 0.96. IUPACName: Ultramark 1621, Mass Spec Std. Density: 1.35g/cm³. Catalog: ACM105809152.
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, Other
Ultrapure Single-walled carbon nanotubes
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherS
Ultrapure SWCNT
Ultrapure SWCNT. Group: Single wall cnt. CAS No. 308068-56-6. >99.99% (SWCNT).
Ultrapure SWCNTs aqueous dispersion
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid;
Ultrapure SWCNTs NMP dispersion
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; Wet
Ulvan - Ulva rotondata-Autumn, originating from the autumnal Ulva rotondata, showcases great application in studying a multitude of ailments, encompassing cancer, diabetes and cardiovascular maladies alike. Synonyms: Sulfated xylorhamnoglycuronan; Ulvan MW. Molecular formula: (C6H9O3SO3)n.
Ulvan - Ulva rotondata-Summer
Ulvan, derived from the Ulva rotondata-Summer algae, is a remarkable natural polysaccharide. This bioactive compound exhibits immense application as a compound owing to its multifaceted anti-inflammatory and antioxidant characteristics. Synonyms: Sulfated xylorhamnoglycuronan; Ulvan MW. Molecular formula: (C6H9O3SO3)n.
UM-164
UM-164 is an inhibitor of Src and p38 MAPK kinases with Kds values of 2.7, 2.2, and 5.5 nM for c-Src, p38α, and p38β, respectively. It inhibits cell growth in a panel of triple-negative breast cancer (TNBC) cell lines (IC50s = 6.1-260 nM) and in a patient-derived TNBC cell line (IC50 = 320 nM). Uses: Protein kinase inhibitors. Synonyms: DAS-DFGO-II; 2-[[6-[4- (2-hydroxyethyl) piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-N-[2-methyl-5-[[3- (trifluoromethyl) benzoyl]amino]phenyl]-1, 3-thiazole-5-carboxamide. Grades: ≥98%. CAS No. 903564-48-7. Molecular formula: C30H31F3N8O3S. Mole weight: 640.68.
UMB-32
UMB-32 is an inhibitor of the BET bromodomain BRD4 (Kd = 550 nM; IC50 = 637 nM) and the bromodomain-containing transcription factor TAF1 (Kd = 560 nM) and TAF1L (Kd = 1.3 μM). Synonyms: N-Tert-Butyl-2-[4-(3,5-Dimethyl-1,2-Oxazol-4-Yl)phenyl]imidazo[1,2-A]pyrazin-3-Amine. Grades: ≥98%. CAS No. 1635437-39-6. Molecular formula: C21H23N5O. Mole weight: 361.4.
UMB 68
UMB 68 is a GHB receptor ligand exhibiting no affinity for GABA(A) or GABA(B) receptors. UMB 68 was shown not to exhibit GHB-like behavioral effects in vivo. Synonyms: UMB68, UMB-68, UMB 68, UMB-68 sodium; Sodium 4-Hydroxy-4methylpentanoate. CAS No. 581099-89-0. Molecular formula: C6H11NaO3. Mole weight: 154.14.
Umbelliferone
Umbelliferone, which is extracted from the root of Angelica biserrata (Shan et Yuan) Yuan et Shan, also known as 7-hydroxycoumarin, hydrangine, skimmetine, and beta-umbelliferone, is a widespread natural product of the coumarin family. It is a yellowish-white crystalline solid that has a slight solubility in hot water, but high solubility in ethanol. Uses: Anti-nociceptive, anti-inflammatory,anti-cancer, anti-oxidant. Synonyms: 7-hydroxy-1-benzopyran-2-one;7-Hydroxycoumarin. Grades: >98%. CAS No. 93-35-6. Molecular formula: C9H6O3. Mole weight: 162.1.
Umbelliferone 7-O-Rutinoside
An impurity of Umbelliferone. Umbelliferone is a metabolite of Coumarin. Umbelliferone is used as a sunscreen agent for its ultraviolet activity. CAS No. 135064-04-9. Molecular formula: C21H26O13. Mole weight: 486.43.
Umbelliferone 99+% (HPLC)
Umbelliferone 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 93-35-6. Pack Sizes: 100g, 250g, 25g, 1Kg. US Biological Life Sciences.
Worldwide
Umbellulone
Offensive principle of the so-called "headache tree". Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitoningene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 546-78-1. Pack Sizes: 10mg. Molecular Formula: C10H14O. US Biological Life Sciences.
Worldwide
Umber
Heterocyclic Organic Compound. CAS No. 12713-03-0. Catalog: ACM12713030.
Umbilical Vein Endothelial Cells, Human (Frozen)
Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Umbilical Vein Endothelial Cells, Human (T-25 flask)
Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
Umbilicaric acid
Umbilicaric acid is an organic polyphenolic carboxylic acid. CAS No. 30666-92-3. Molecular formula: C25H22O10. Mole weight: 482.44.
Umbralisib
Umbralisib is an orally bioavailable and selective PI3K delta inhibitor that targets delta isoform with nanomolar potency, which is approximately 1000-fold selective over alpha isoform, >30-50 fold over beta isoform and >15-50 fold over gamma isoforms. Umbralisib is developed for lymphoma therapy. Synonyms: TGR-1202; TGR 1202; TGR1202; RP5264; 2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one. CAS No. 1532533-67-7. Molecular formula: C31H24F3N5O3. Mole weight: 571.5.
Umeclidinium bromide
Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). Synonyms: GSK-573719, GSK573719, GSK 573719, GSK-573719A, GSK573719A, GSK 573719A, Incruse Ellipta, Umeclidinium bromide. Grades: 0.99. CAS No. 869113-09-7. Molecular formula: C29H34BrNO2. Mole weight: 508.5.
UMI-77
UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. Synonyms: UMI-77, UMI77, UMI 77. Grades: >98%. CAS No. 518303-20-3. Molecular formula: C18H14BrNO5S2. Mole weight: 468.34.
Umibecestat free base
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP-transgenic mice. Group: Inhibitors. Alternative Names: Umibecestat; CNP-520; CNP 520; CNP520. CAS No. 1387560-01-1. Molecular formula: C19H15ClF7N5O2. Mole weight: 513.8. Appearance: Solid powder. Purity: >98%. IUPACName: N-{6-[(3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-5-fluoropyridin-2-yl}-3-chloro-5- (trifluoromethyl)pyridine-2-carboxamide. Canonical SMILES: O=C (C1=NC=C (C (F) (F)F)C=C1Cl)NC2=NC ([C@]3 (C)CO[C@] (C (F) (F)F) (C)C (N)=N3)=C (F)C=C2. Catalog: ACM1387560011.
Umifenovir
Arbidol is an antiviral agent using for the treatment of influenza infection in Russia and China. It inhibits membrane fusion and prevents contact between the virus and target host cells. Fusion between the viral capsid and the cell membrane of the target cell is inhibited and this prevents viral entry to the target cell. Although some Russian studies have shown it to be effective, it is not approved for use in Western countries. Synonyms: Arbidol; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grades: ≥95%. CAS No. 131707-25-0. Molecular formula: C22H25BrN2O3S. Mole weight: 477.41.
Umifenovir Glucuronide
Umifenovir Glucuronide is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylthio)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic Acid; Arbidol O-Glucuronide; 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic acid; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-(β-D-glucopyranuronosyloxy)-1-methyl-2-[(phenylthio)methyl]-, ethyl ester. Grades: >98%. CAS No. 1130900-96-7. Molecular formula: C28H33BrN2O9S. Mole weight: 653.54.
Umifenovir Sulfate
Umifenovir Sulfate is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: Ethyl 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylsulfanyl)methyl]-5-(sulfooxy)-1H-indole-3-carboxylate; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-, 3-ethyl ester; 3-Ethyl Ester 6-Bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-1H-indole-3-carboxylic Acid; Arbidol Sulfate. Grades: >98%. CAS No. 1443454-70-3. Molecular formula: C22H25BrN2O6S2. Mole weight: 557.48.
Umirolimus
A semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group. It is one of the most hydrophobic tacrolimus analogues. It binds to the cytosolic FK-binding protein 12 (FKBP12) to inhibit the mammalian target of rapamycin (mTOR) pathway. Synonyms: Biolimus; Biolimus A9; TRM 986; 42-O-(2-Ethoxyethyl)rapamycin. Grades: >95% by HPLC. CAS No. 851536-75-9. Molecular formula: C55H87NO14. Mole weight: 986.28.