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| Product | Description | |
|---|---|---|
| K 01-162 | K 01-162 binds and destabilizes AβO (β-amyloid( EC50= 0.080 mM; IC50= 80 nM), can reduce the brain amyloid burden that exists in both fibrillar and RIPA-soluble, non-fibrillar forms. Uses: Stabilizes hydrophobic core i of aβ42 peptide (residues 17-21) to its α-helical conformation by interacting specifically in this region. in vivo. Synonyms: 7-bromo-N,N-dimethyl-9H-fluoren-2-amine; 9H-Fluoren-2-aMine, 7-broMo-N,N-diMethyl-. Grades: ≥98%. CAS No. 677746-25-7. Molecular formula: C15H14BrN. Mole weight: 288.19. |  |
| K02288 | K02288 is a highly selective 2-aminopyridine based inhibitor with in vitro activity against ALK2 at low nanomolar concentrations similar to the current lead compound LDN-193189. K02288 specifically inhibits the BMP-induced Smad pathway without affecting TGF-b signaling and induced dorsalization of zebrafish embryos. Synonyms: K-02288; 3-(6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol. Grades: >98%. CAS No. 1431985-92-0. Molecular formula: C20H20N2O4. Mole weight: 352.38. | |
| K 02288 | K 02288. Group: Biochemicals. Grades: Purified. CAS No. 1431985-92-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| K03861 | K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. Synonyms: AUZ 454; K 03861; K-03861; Urea, N-[4-[(2-amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-; 1-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-3-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea. Grades: 98%. CAS No. 853299-07-7. Molecular formula: C24H26F3N7O2. Mole weight: 501.50. | |
| K-1115A | It is produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115A inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide (IC50 = 100 microM), and the production of collagenase in IL-1 alpha-stimulated rat synovial cells (IC50 = 60 microM). Synonyms: K1115 A; 2-Anthracenecarboxylic acid, 9,10-dihydro-3,8-dihydroxy-9,10-dioxo-1-propyl-. CAS No. 208525-17-1. Molecular formula: C18H14O6. Mole weight: 326.30. | |
| K1115 B1 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B1 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Synonyms: XR-573. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| K1115 B2 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B2 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Molecular formula: C23H26O9. Mole weight: 446.45. | |
| K114 | K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC 50 of 20-30 nM [1]. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 872201-12-2. Pack Sizes: 2 mg; 5 mg. Product ID: HY-103470. |  |
| K 114 | K 114. Group: Biochemicals. Grades: Purified. CAS No. 872201-12-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| K-115 | K-115, also called as Ripasudil or Glanatec, a selective ROCK inhibitor (IC50 =31 nM), is a promising emerging antiglaucoma drug, and was thus approved by the Japanese administrative authority in 2014. Synonyms: 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinolineGlanatecK-115; K 115; K115K115 compoundripasudil. CAS No. 223645-67-8. Molecular formula: C15H18FN3O2S. Mole weight: 323.39. | |
| K-11777 | K-11777 is a potent, irreversible cysteine protease inhibitor. Besides, K11777 is not only a substrate but also a mechanism-based inhibitor of CYP3A4. Synonyms: 4-methyl-N-((S)-1-oxo-3-phenyl-1-(((S,E)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)amino)propan-2-yl)piperazine-1-carboxamide; APC-3316; APC3316; APC 3316; K-11777; K 11777; K11777; K 777; K-777; K777; CRA-3316; CRA3316; CRA 3316. Grades: >98%. CAS No. 233277-99-1. Molecular formula: C32H38N4O4S. Mole weight: 574.74. | |
| K-13 | K-13 is a noncompetitive inhibitor of angiotensin I converting enzyme from Micromonospora halophytica subsp. exilisia K-13. Synonyms: L-Tyrosine, N-acetyl-L-tyrosyl-L-tyrosyl-3-hydroxy-, cyclic (1-3(sup 3))-ether. CAS No. 108890-90-0. Molecular formula: C29H29N3O8. Mole weight: 547.55. | |
| K134 | K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, and has been shown to exhibit more potent anti-platelet activity than cilostazol. In vivo studies have demonstrated the anti-thrombotic and anti-hyperplastic effects of K-134, and that these effects of K-134 are stronger than those of cilostazol. Synonyms: 1-cyclopropyl-1-[(1R,2R)-2-hydroxycyclohexyl]-3-[3-[(2-oxo-1H-quinolin-6-yl)oxy]propyl]urea; 6-(3-(3-cyclopropyl-3-(2-hydroxycyclohexyl)ureido)propoxy)-2(1H)-quinolinone; K 134 compound; K-134 compound; K134 compound; OPC 33509; OPC-33509; K-134. CAS No. 189362-06-9. Molecular formula: C22H29N3O4. Mole weight: 399.48. | |
| K145 | K145 is a selective sphingosine kinase-2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose-dependent manner with an IC50 of 4.30±0.06 μM. K145 also exhibited inhibitory effects on the growth of U937 cells as well as apoptotic effects in U937 cells. K145 exhibits comparable in vivo anti-tumor activity to tamibarotene, while concomitantly exhibiting less toxicity in this U937 xenograft cancer model. Synonyms: SphK2 inhibitor; K 145; K-145. Grades: >98%. CAS No. 1309444-75-4. Molecular formula: C18H24N2O3S. Mole weight: 348.46. | |
| K145 hydrochloride | K145 (3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione) is a selective inhibitor of sphingosine kinase-2 (SphK2) and an anticancer agent. K145 selectively inhibited SphK2 in a dose-dependent manner with an IC50 of 4.30 +/- 0.06 μM with no inhibition of SphK1 at concentrations up to 10 μM. K145 significantly suppressed the growth of U937 tumors in nude mice and the growth of JC tumor cells in BALB/c mice. Synonyms: SphK2 inhibitor; K 145 hydrochloride; K-145 hydrochloride. Grades: >98%. CAS No. 1449240-68-9. Molecular formula: C18H25ClN2O3S. Mole weight: 384.92. | |
| K145 hydrochloride | K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC 50 of 4.3 μM and a K i of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1449240-68-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15779A. | |
| K19 Dye | K19 Dye is an amphiphilic ruthenium sensitizer with a good molar extinction coefficient, which remains stable under thermal stress and light soaking. It can be synthesized by forming a reaction mixture of 4,4'-Bis(p-hexyloxystyryl)-2,2'-bipyridine, dichloro(p-cymene)ruthenium(II) dimer, and 4,4'-dicarboxylic acid-2,2'-bipyridine. It shows an overall power conversion efficiency (PCE) of 11% and can be used as an active material in electrochemical applications.]. Uses: Electron transfer from k-19 dye to the conduction band of titania is completed within 20 fs while charge recombination has a half-life of 800 μs. the high extinction coefficient of this sensitizer enable realization of a new generation thin-film dye-sensitized solar cells (dscs) yielding high conversion efficiency at full sunlight, even with viscous electrolytes based on ionic liqs. or nonvolat. Group: Organic solar cell (opv) materials. Alternative Names: Ru(4,4-dicarboxylic acid-2,2 inverted exclamation marka-bipyridine)(4,4 inverted exclamation marka-bis(p-hexyloxystyryl)-2,2-bipyridine)(NCS)2. CAS No. 847665-45-6. Pack Sizes: 250 mg in glass insert. Molecular formula: 1022.21. Mole weight: C52H52N6O6RuS2. CCCCCCOC1=CC=C (C=C1)C=CC2=CC (=NC=C2)C3=NC=CC (=C3)C=CC4=CC=C (C=C4)OCCCCCC. C1=CN=C (C=C1C (=O)O)C2=NC=CC (=C2)C (=O)O. C (=[N-])=S. C (=[N-])=S. [Ru+2]. InChI=1S/C38H44N2O2. C12H8N2O4. 2CNS. Ru/c1-3-5-7-9-27-41-35-19-15-31 (16-20-35)11-13-33-23-25-39-37 (2 |  |
| K19 Dye | K19 Dye is an amphiphilic ruthenium sensitizer with a good molar extinction coefficient, which remains stable under thermal stress and light soaking. It can be synthesized by forming a reaction mixture of 4,4'-Bis(p-hexyloxystyryl)-2,2'-bipyridine, dichloro(p-cymene)ruthenium(II) dimer, and 4,4'-dicarboxylic acid-2,2'-bipyridine. It shows an overall power conversion efficiency (PCE) of 11% and can be used as an active material in electrochemical applications.]. Uses: Electron transfer from k-19 dye to the conduction band of titania is completed within 20 fs while charge recombination has a half-life of 800 μs. the high extinction coefficient of this sensitizer enable realization of a new generation thin-film dye-sensitized solar cells (dscs) yielding high conversion efficiency at full sunlight, even with viscous electrolytes based on ionic liqs. or nonvolatile solvents, making solar cell devices exhibit excellent stability under light soaking. Group: Dye sensitizers. Alternative Names: Ru(4,4-dicarboxylic acid-2,2 inverted exclamation marka-bipyridine)(4,4 inverted exclamation marka-bis(p-hexyloxystyryl)-2,2-bipyridine)(NCS)2. CAS No. 847665-45-6. Molecular formula: C52H52N6O6RuS2. Mole weight: 1022.21. Appearance: Black powder. Canonical SMILES: CCCCCCOC1=CC=C (C=C1)C=CC2=CC (=NC=C2)C3=NC=CC (=C3)C=CC4=CC=C (C=C4)OCCCCCC. C1=CN=C (C=C1C (=O)O)C2=NC=CC (=C2)C (=O)O. C (=[N-])=S. C (=[N-])=S. [Ru+2]. Catalog: ACM847665456-1. |  |
| K19 Dye, 85% | K19 Dye, 85%. Group: Dye-sensitized solar cell (dssc) materials. CAS No. 847665-45-6. | |
| k-252a | K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene. Group: Inhibitors. CAS No. 99533-80-9. Molecular formula: C27H21N3O5. Mole weight: 467.47. Purity: >98 %. Catalog: ACM99533809. | |
| K252a | K252a. Group: Biochemicals. Alternative Names: 2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acd methyl ester; Antibiotic K252a; Antibiotic SF 2370. Grades: Highly Purified. CAS No. 97161-97-2. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C27H21N3O5. US Biological Life Sciences. | Worldwide |
| K 252a | K 252a. Group: Biochemicals. Grades: Purified. CAS No. 99533-80-9. Pack Sizes: 200ug. US Biological Life Sciences. | Worldwide |
| K-252a | K-252a is an antibiotic, PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK family. Antiproliferative and apoptosis inducer. Cell cycle arrest inducer. Potential drug for psoriasis treatment. Source:Isolated from Nonomuraea longicatena chiba. Group: Biochemicals. Grades: Highly Purified. CAS No. 99533-80-9. Pack Sizes: 100ug, 1mg. Molecular Formula: C27H21N3O5. US Biological Life Sciences. | Worldwide |
| K252a (2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acd Methyl Ester, Antibiotic K252a, Antibiotic SF 2370, SF 2370) | K252a is an alkaloid isolated from Nocardiopsis sp. soil fungi. This compound is a highly potent cell permeable CaM Kinase II inhibitor (IC50=1.8nM). At higher concentrations it also inhibits broad spectrum of protein kinases (1-8). It is an excellent research tool of NGF receptors-trk-signal transduction due to its potent inhibition of trk-NGF receptor-tyrosine kinase activity. Group: Biochemicals. Alternative Names: 2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acd Methyl Ester; Antibiotic K252a; Antibiotic SF 2370; SF 2370. Grades: Highly Purified. CAS No. 97161-97-2. Pack Sizes: 500ug, 5mg. US Biological Life Sciences. | Worldwide |
| K252b | K252b. Group: Biochemicals. Alternative Names: (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acid; [9S-(9α,10 β,12α)]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acid; Antibiotic K 252b; KT 5556. Grades: Highly Purified. CAS No. 99570-78-2. Pack Sizes: 250ug. Molecular Formula: C26H19N3O5, Molecular Weight: 453.45. US Biological Life Sciences. | Worldwide |
| K-252b | A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K-252b exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases, notably myosin light chain kinase, camp-dependent protein kinase (PKA), protein kinase C (PKC) and cgmp-dependent protein kinase (PKG). Synonyms: (9r,10s,12s)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid. Grades: >98% by HPLC. CAS No. 99570-78-2. Molecular formula: C26H19N3O5. Mole weight: 453.45. | |
| K-252c | K-252c. Group: Biochemicals. Grades: Purified. CAS No. 85753-43-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| K-252c | K252c, a metabolite product of Nocardiopsis Sp., has been found to be a protein kinase C inhibitor and exhibit antiviral activities against GCV-sensitive and-resistant strains at some extent. Uses: K252c inhibits protein kinase c. its reported ic50 value of 214 nm on rat brain enzyme k252c is cytotoxic for a549 and p388 cancer celllines showing ic50 = 2-3 μm. Synonyms: Staurosporine aglycone; K252C; 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one. Grades: ≥97%. CAS No. 85753-43-1. Molecular formula: C20H13N3O. Mole weight: 311.34. | |
| K 259-2 | K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase, was isolated from the cultured broth of Micromonospora olivasterospora K-259. IC50 values for the effect of K-259-2 against Ca2+ and calmodulin-stimulated activity of the enzyme preparations from bovine brain and heart were 6.6 and 2.9 microM, respectively. Synonyms: K-259-2; 1,6,8-Trihydroxy-3-[(Z)-2-ethyl-2-butenyl]-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid. CAS No. 102819-46-5. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| K2 Ag (Marijuana Synthetic K2) (BSA) | K2 is synthetic marijuana which acts on cannabinoid receptors that are found on immune cells and thrombocytes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| K 41 | K 41 is originally isolated from Streptomyces hygroscopicus K-41 with anti-gram-positive bacteria activity. Synonyms: (29S)-9,13:17,20:21,24-trianhydro-4,8,10,12,14,18,19,22,23,26,28,30-dodecadeoxy-4,12,14,26,28-pentamethyl-6,16-di-C-methyl-5,6,11,15-tetra-O-methyl-27-O-[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]-L-xylo-L-manno-α-D-gluco-L-ribo-α-L-gluco-D-glycero-3,13,29-triacontotriulo-13,16-furanose-3,7:29,25-dipyranosonic acid. CAS No. 53026-37-2. Molecular formula: C48H82O18. Mole weight: 947.15. | |
| K 41498 | K 41498 is a potent and highly selective CRF2 receptor antagonist. Its Ki values are 425, 0.66 and 0.62 nM for human CRF1, CRF2α and CRF2β receptors respectively. It prevents sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. It blocks urocortin-induced hypotension following systemic administration in rats in vivo and is used to treat hypertension in rodents. Synonyms: D-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-norleucyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparaginyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-α-aspartyl-L-threonyl-L-Isoleucinamide. Grades: >98%. CAS No. 434938-41-7. Molecular formula: C162H276N48O46. Mole weight: 3632.26. | |
| K4-S4 | K4-S4 has antibacterial activity. | |
| K562 Transfection Reagent | Electroporation buffer optimized for K562 AML leukemia cells. Optimized electroporation protocol provided for transfection of si/miRNA, DNA, mRNA, and small proteins. Feature high transfection efficacy and cell viability. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 6571. |  Nevada, Texas, USA |
| K 579 | K 579, a cyanopyrrolidine compound, is a potent and slow-binding dipeptidyl peptidase IV (DPP IV) inhibitor. It has been shown to reduce blood DPP IV activity and attenuate glucose excursion following glucose loading in Zucker fatty rats. It reduces plasma glucose concentration by augmenting GLP-1 and insulins response after glucose intake in rats in vivo. It is used as a long-acting hypoglycemic agent. Synonyms: K 579; K579; K-579; (2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile; (S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile; DPP IV Inhibitor IV. Grades: ≥99% by HPLC. CAS No. 440100-64-1. Molecular formula: C17H24N6O. Mole weight: 328.41. | |
| K 579 | K 579. Group: Biochemicals. Grades: Purified. CAS No. 440100-64-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| K-604 dihydrochloride | K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 ( ACAT-1 ) inhibitor with an IC 50 of 0.45±0.06 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 217094-32-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100400A. | |
| K67 | K67 is a specific inhibitor that inhibits the interaction between the DC domain of KEAP1 and the S349 phosphorylated KIR of p62/SQSTM1. Synonyms: N,N'-[2-(2-Oxopropyl)Naphthalene-1,4-Diyl]Bis(4-Ethoxybenzenesulfonamide). Grades: ≥98% by HPLC. CAS No. 2046250-48-8. Molecular formula: C29H30N2O7S2. Mole weight: 582.7. | |
| K6PC-5 | K6PC-5 is a Sphingosine kinase 1 (SphK1 or SK1) activator that increases sphingosine-1-phosphate (S1P) production, an active metabolite of sphingolipid. S1P can modulate multiple cellular responses including [Ca2+] signaling, growth, survival, and differentiation. K6PC-5 regulates both differentiation and proliferation of keratinocytes via [Ca2+]i responses through S1P production, which may be used for the treatment of skin disorders characterized by abnormal differentiation and proliferation, such as atopic dermatitis and psoriasis. Uses: Potential treatment of skin disorders with abnormal differentiation and proliferation. Synonyms: K6PC-5; K6PC 5; K6PC5; Dihydroxyisopropyl capryloylcaprylamide; Decanamide, 2-hexyl-N-(2-hydroxy-1-(hydroxymethyl)ethyl)-3-oxo. Grades: 98%. CAS No. 756875-51-1. Molecular formula: C19H37NO4. Mole weight: 343.5. | |
| K-7174 | K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib. K-7174 is also a GATA-specific inhibitor, which may have potential application in treating anemia of chronic disease. Synonyms: K-7174; K 7174; K7174. Grades: 0.98. CAS No. 191089-59-5. Molecular formula: C33H48N2O6. Mole weight: 568.74. | |
| K-7174 | K-7174 is an orally active proteasome and GATA inhibitor. K-7174 is a cell adhesion inhibitor. K-7174 induces cell apoptosis. K-7174 shows antitumor activities, it can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191089-59-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12743. | |
| K-7174 dihydrochloride | K-7174 dihydrochloride is an orally active proteasome and GATA inhibitor. K-7174 dihydrochloride is a cell adhesion inhibitor. K-7174 dihydrochloride induces cell apoptosis. K-7174 dihydrochloride shows antitumor activities, it can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191089-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12743A. | |
| K-7174 dihydrochloride | K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, without obvious side effects in a murine myeloma model. Moreover, K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib. Synonyms: 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride; K7174; K 7174; K-7174; K-7174-2HCl; K-7174 dihydrochloride. Grades: >98%. CAS No. 191089-60-8. Molecular formula: C33H50Cl2N2O6. Mole weight: 641.67. | |
| K777 | K777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC 50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi , and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC 50 values of 0.68 nM and 0.87 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 233277-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119293. | |
| K-8012 | K-8012, a sulindac (HY-B0008) analog, is a potent antagonist of RXRa. The IC 50 value for K-8012 to inhibit 9-cis-RA-induced Gal4-RXRa-LBD trans-activation were about 9.2 μM. K-8012 exerts improved anticancer activity over sulindac in a RXRa-dependent manner. K-8012 exhibits activity in inhibiting the tRXRa-mediated PI3K/AKT signaling pathway. K-8012 induces apoptosis and inhibits AKT activation by preventing tRXRa from binding to p85a [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346513-17-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121435. | |
| K811 | K811 is a specific inhibitor of ASK1, which can prolong the survival time of the mouse model of amyotrophic lateral sclerosis. Synonyms: AC-31496. Grades: ≥98% by HPLC. CAS No. 1355228-38-4. Molecular formula: C29H26N4O5. Mole weight: 510.5. | |
| K812 | K812 is a specific inhibitor of ASK1 that can prolong the survival time of a mouse model of amyotrophic lateral sclerosis. Synonyms: AC-31495. Grades: ≥98% by HPLC. CAS No. 1355228-39-5. Molecular formula: C30H27N3O5. Mole weight: 509.6. | |
| K 858 | K 858. Group: Biochemicals. Grades: Purified. CAS No. 72926-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| K-858 | K-858 is a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells. K858 blocked centrosome separation, activated the spindle checkpoint, and induced mitotic arrest in cells accompanied by the formation of monopolar spindles. Synonyms: K-858; K 858; K858. Grades: 98%. CAS No. 72926-24-0. Molecular formula: C13H15N3O2S. Mole weight: 277.34. | |
| KA 7038IV | KA 7038IV is originally isolated from Streptomyces sp. KA-7038 with anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. Synonyms: Antibiotic KA 7038IV; BRN 1387553; 2-Amino-3,6-dihydroxy-4-methoxy-5-(methylamino)cyclohexyl 2,6-diamino-2,3,4,6-tetradeoxyhexopyranoside. CAS No. 73491-60-8. Molecular formula: C14H30N4O5. Mole weight: 334.41. | |
| KAD-1229 calcium hydrate | KAD-1229 calcium hydrate. Group: Biochemicals. Alternative Names: (S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid calcium salt hydrate. Grades: Highly Purified. CAS No. 207844-01-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C19H27NO4·½Ca. US Biological Life Sciences. | Worldwide |
| KAD-1229-d8 Calcium Hydrate | KAD-1229 binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Group: Biochemicals. Alternative Names: (S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric Acid-d8 Calcium Salt Hydrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KAD-1229 (Mitiglinide) | KAD-1229 binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Group: Biochemicals. Alternative Names: Mitiglinide. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kadsuracoccinic Acid A | Heterocyclic Organic Compound. CAS No. 1016260-22-2. Molecular formula: C30H44O4. Mole weight: 468.7. Appearance: Powder. Purity: 0.98. IUPACName: (Z,6Z)-6-[(3aS,6S,7S,9aS,9bS)-6-(2-carboxyethyl)-3a,6,9b-trimethyl-7-prop-1-en-2-yl-2,4,7,8,9,9a-hexahydro-1H-cyclopenta[a]naphthalen-3-ylidene]-2-methylhept-2-enoic acid. Canonical SMILES: CC (=C)C1CCC2C (=CCC3 (C2 (CCC3=C (C)CCC=C (C)C (=O)O)C)C)C1 (C)CCC (=O)O. Density: 5mg 10mg 20 mg. Catalog: ACM1016260222. | |
| Kadsurenone | Kadsurenone. Uses: Scientific research. Group: Natural products. CAS No. 95851-37-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10663. | |
| Kaempferia Galanga (Galanga Root Oil) - CO2 | Galangal CO2 select is extracted from the dried rhizomes (underground stems) of Kaempferia galanga, a small tropical plant that is closely related to ginger; it is commonly cultivated in India, Indonesia, and Malaysia for essential oilsproduction, medicinal use, and as an ingredient in curry. Galangal Root oil is fresh, spicy, woody, ginger-like oil, steam distilled from the plant's rhizome. In fact, Galangal Root is closely related to true ginger and cardamom so it's not surprising that Galangal Root blends well with these oils and shares similar notes. Blends Well With: Black Pepper, Cardamom, Carnation, Cedarwood, Chamomile (Roman), Cinnamon, Clove, Coriander, Cypress, Elemi, Fennel, Frankincense, Geranium, Ginger, Jasmine, Juniper Berry, Laurel Leaf, Lavandin, Lavender, Liquidambar (Styrax), Marjoram, Myrrh, Myrtle, Orris, Palmarosa, Patchouli, Pine, Rose, Sage, Sandalwood, Spikenard, Tarragon, Vetiver. Uses: Pharmaceutical. Group: Plant Extracts. INCI Names: Kaempferia Galanga Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 92347-13-2. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GL-001. Olfactive Profile: Fresh, spicy, characteristic odour of galanga. EC No: 296-200-2. Origin: Indonesia. |  New Jersey |
| Kaempferide | Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. P-glycoproteins. Kaempferide has antiviral activities. Group: Inhibitors. CAS No. 491-54-3. Molecular formula: C16H12O6. Mole weight: 300.26. Appearance: Solid. Purity: 0.99. Canonical SMILES: O=C1C (O)=C (C2=CC=C (OC)C=C2)OC3=CC (O)=CC (O)=C13. Catalog: ACM491543. | |
| Kaempferide | Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Kaempferol 4'-O-methyl ether. CAS No. 491-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15449. | |
| Kaempferide | Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumor possibilities. Impurity of Icaritin (I163700). Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-trihydroxy-4'-methoxy-flavone; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-O-methyl ether; Kaempferol 4'-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: Highly Purified. CAS No. 491-54-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Kaempferide | Kaempferide is an O-methylated flavonol. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. Uses: Antioxidant. Synonyms: 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,5,7-trihydroxy-4'-methoxy-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 4'-O-Methylkaempherol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-methyl ether; Kaempferol 4'-O-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: >98%. CAS No. 491-54-3. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Kaempferin (Kaempferol-3-rhamnoside) | Kaempferin (Kaempferol-3-rhamnoside). Group: Biochemicals. Alternative Names: Kaempferol-3-rhamnoside; Afzelin; Afzeloside. Grades: Plant Grade. CAS No. 482-39-3. Pack Sizes: 10mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences. | Worldwide |
| Kaempferitrin | Cytotoxic and anti-inflammatory compound (weak). Antioxidant and lipid peroxidation inhibitor. Free radical scavenger. Inhibitor of myeloperoxidase activity. Hypoglycemic, decreases blood glucose levels in diabetic and normal rats. Insulinomimetic. Modulates glucose homeostasis. Decreaes blood glucose levels and stimulates glucose uptake in muscle. Inhibits GLUT4 mediated glucose uptake in differentiated 3T3-L1 cells. Improves insulin resistance by the activation of the classical insulin transduction pathway. Increases adiponectin secretion in 3T3-L1 adipocytes. Antinoniceptive. May have antidyslipidemic activity. Source:Isolated from Calendula officinalis. Group: Biochemicals. Grades: Highly Purified. CAS No. 482-38-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H30O14, Method for Determining. US Biological Life Sciences. | Worldwide |
| Kaempferitrin | Kaempferitrin is a natural flavonoid, possesses antinociceptive, anti-inflammatory, anti-diabetic, antitumoral and chemopreventive effects, and activates insulin signaling pathway. Uses: Scientific research. Group: Natural products. Alternative Names: Lespedin; Lespenephryl. CAS No. 482-38-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0628. | |
| Kaempferol | Kaempferol - Product ID: NST-10-24. Category: Flavonoids. Alternative Names: 3,4',5,7-Tetrahydroxyflavone. Purity: 98%. Test method: HPLC. CAS No. 520-18-3. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: Yellow Powder. Molecular formula: C15H10O6. Mole weight: 286.23. Storage: +2 +8 °C. |  |
| Kaempferol | Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. It has many functions such as anti-cancer, diuretic, anti-inflammatory, antioxidant, anti-bacterial, and anti-virus. Kaempferol can be used in food additive. Uses: Anti-inflammatory; diuretic; antioxidant; inhibitor of topoisomerase-ii. Synonyms: Robigenin; Kaempherol; Kempferol; Populnetin; Rhamnolutein. Grades: >98%. CAS No. 520-18-3. Molecular formula: C15H10O6. Mole weight: 286.23. | |
| Kaempferol | Kaempferol. Group: Biochemicals. Grades: Purified. CAS No. 520-18-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Kaempferol | Kaempferol is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods. Kaempferol is a yellow crystalline solid with a melting point of 276 - 278°C (529 - 532°F). It is slightly soluble in water and highly soluble in hot ethanol, ethers, and DMSO. Kaempferol acts as an Antioxidants by reducing oxidative stress. Many studies suggest that consuming kaempferol may reduce the risk of various cancers, and it is currently under consideration as a possible cancer treatment. Group: Inhibitors. Alternative Names: 5,7,4'-Trihydroxyflavonol. CAS No. 520-18-3. Molecular formula: C15H10O6. Mole weight: 286.24. Appearance: Yellow powder. Purity: 0.98. IUPACName: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)chromen-4-one. Canonical SMILES: C1=CC (=CC=C1C2=C (C (=O)C3=C (C=C (C=C3O2)O)O)O)O. Density: 1.2981 g/cm³. ECNumber: 208-287-6. Catalog: ACM520183. | |
| Kaempferol | Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Kempferol; Robigenin. CAS No. 520-18-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14590. | |
| Kaempferol | 25mg Pack Size. Group: Bioactive Small Molecules, Aroma Chemicals, Biochemicals, Organics, Research Organics & Inorganics. Formula: C15H10O6. CAS No. 520-18-3. Prepack ID 35856397-25mg. Molecular Weight 286.24. See USA prepack pricing. |  |
| Kaempferol 10% HPLC (Sophora japonica) | Kaempferol 10% HPLC (Sophora japonica). Categories: l-selenomethionine; 3211-76-5. |  CA, FL & NJ |
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