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| Product | Description | |
|---|---|---|
| Kazusamycin B | A minor component of the leptomycin complex produced by some streptomyces sp.; an hydroxylated analogue of leptomycin A, a nuclear export inhibitor; displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice; also possesses strong antibacterial and antifungal activity. Synonyms: PD 124895; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-. Grades: >95% by HPLC. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.70. |  |
| Kazusamycin B | Heterocyclic Organic Compound. Alternative Names: PD 124895;4,8,10,14,18,20,22-Heptamethyl-16-hydroxymethyl-5,19-dihydroxy-17-oxo-2,6,8,12,14,22-tetracosahexenedioic acid δ-lactone;Antibiotic CL-1957E;Antibiotic PD-124895;CL-1957E;Kazusamycin B. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.7. Appearance: Film. Purity: 0.95. Canonical SMILES: CC1C=CC (=O)OC1/C=C/C (=C\\C (C)C/C=C/C (=C/C (CO)C (=O)C (C)C (C (C)C/C (=C/C (=O) O)/C)O)/C)/C. Catalog: ACM107140307. |  |
| Kazusamycin B (Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895 ) | Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp. It is an hydroxylated analogue of Leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895. Grades: Highly Purified. CAS No. 107140-30-7. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| KB-05 | KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1956368-15-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149461. |  |
| KB-0742 | KB-0742 is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416873-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478. | |
| KB-0742 dihydrochloride | KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416874-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478A. | |
| KB-0742 HCl | KB-0742 is an orally bioavailable, selective CDK9 inhibitor with potent anti-tumor activity in CRPC models. In 22Rv1 cells, KB-0742 rapidly downregulates nascent transcription, preferentially depleting short half-life transcripts and AR-driven oncogenic programs. In vivo, oral administration of KB-0742 significantly reduced tumor growth in CRPC, supporting CDK9 inhibition as a promising therapeutic strategy to target AR dependence in CRPC. Group: Inhibitors. Alternative Names: KB-0742; KB0742; KB 0742 2HCl; KB 0742 dihydrochloride; KB 0742 hydrochloride. CAS No. 2416874-75-2. Molecular formula: C16H27Cl2N5. Mole weight: 360.33. Appearance: Solid powder. Purity: >98%. IUPACName: (1S,3S)-N1-(5-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine dihydrochloride. Canonical SMILES: CCC (CC)C1=NC2=CC=NN2C (N[C@@H]3C[C@@H] (N)CC3)=C1. Cl. Cl. Catalog: ACM2416874752. | |
| KB3022 | A cyclooxygenase (COX) inhibitor. Synonyms: ethyl 2-[2-[4,5-bis(4-methoxyphenyl)-1,3-thiazol-2-yl]pyrrol-1-yl]acetate; 1H-Pyrrole-1-acetic acid, 2-(4,5-bis(4-methoxyphenyl)-2-thiazolyl)-, ethyl ester; ethyl 2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)pyrrol-1-ylacetate; KB 3022; KB-3022; KBT-3022. CAS No. 101001-34-7. Molecular formula: C25H24N2O4S. Mole weight: 448.53. | |
| KBC-007 | KBC-007 is an analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse at 0.5 ng/ml, and indices IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at 8 ng/ml. Synonyms: 8-(Diheptylamino)-N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]octanamide. Grades: ≥95%. CAS No. 1037297-61-2. Molecular formula: C46H92N2O9. Mole weight: 817.23. | |
| kb NB 142-70 | kb NB 142-70. Group: Biochemicals. Grades: Purified. CAS No. 1233533-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| kb NB 142-70 | kb-NB142-70 is a derivative of the PKD1 inhibitor CID755673, with approximately 6-fold greater potency (IC50 for inhibition of PKD1=28.3 nM vs. 182 nM for CID755673). kb-NB142-70 dose dependently inhibits proliferation of PC3 prostate cancer cell, and blocks migration of the prostate cancer lines PC3 and DU145. Synonyms: kb NB 142-70; kb NB142-70; kb NB-142-70. Grades: >98%. CAS No. 1233533-04-4. Molecular formula: C11H9NO2S2. Mole weight: 251.32. | |
| kb-NB77-78 | kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor). Synonyms: 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-b]pyridin-5-one; kb-NB77-78; kb-NB-77-78; kb-NB 77-78; kb-NB7778; kb-NB-7778; kb-NB 7778. Grades: >98%. CAS No. 1350622-33-1. Molecular formula: C18H25NO3Si. Mole weight: 331.48. | |
| KBP-Type Peptidyl-Prolyl Cis-Trans Isomerase, Recombinant | SlyD is a putative folding helper protein from the Escherichia coli cytosol, which has N-terminal prolyl isomerase domain of the FKBP type and a most likely unstructured C-terminal tail. SlyD is an important factor in the biosynthesis of the metal cluster in the [NiFe]-hydrogenase enzymes, and exhibits several activities including that of a peptidyl-prolyl isomerase. Slyd recombinant produced in e. coli is a single, non-glycosylated polypeptide chain containing 196 amino acids and having a molecular mass of 21 kda. Group: Enzymes. Synonyms: FKBP-Type Peptidyl-Prolyl Cis-Trans Isomerase; SlyD. Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. SlyD. Mole weight: 21 kDa. Activity: > 66 nmoles/min/ug. Stability: SlyD although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Appearance: Sterile Filtered colorless solution. Source: E. coli. FKBP-Type Peptidyl-Prolyl Cis-Trans Isomerase; SlyD. Cat No: NATE-0852. |  |
| KBR-16 | KBR-16 is a novel nuclear receptor retinoic acid receptor-related orphan receptor-gamma (RORgamma) inhibitor derived from ursolic acid. It is used for the treatment of inflammation with excellent oral bioavailability and favorable pharmacokinetic profile. Uses: The treatment of inflammation. Synonyms: KBR 16; KBR16. | |
| Kb-r7943 mesylate | KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux. Group: Inhibitors. CAS No. 182004-65-5. Molecular formula: C16H17N3O3S.CH3SO3H. Mole weight: 427.5. Appearance: Solid. Purity: >99 %. Canonical SMILES: NC (SCCC1=CC=C (OCC2=CC=C ([N+] ([O-])=O)C=C2)C=C1)=N. CS (=O) (O)=O. Catalog: ACM182004655. | |
| KB-R7943 mesylate | KB-R7943 is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Synonyms: KB-R7943; KB R7943; KB-R 7943; KB-R7943 mesylate. Grades: 98%. CAS No. 182004-65-5. Molecular formula: C17H21N3O6S2. Mole weight: 427.49. | |
| KB-R7943 mesylate | KB-R7943 mesylate. Group: Biochemicals. Grades: Purified. CAS No. 182004-65-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KB SRC 4 | KB SRC 4. Group: Biochemicals. Grades: Purified. CAS No. 1380088-03-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KB SRC 4 | KB SRC 4 is a cell-permeable, potent and highly selective c-Src inhibitor with Kd value of 86 nM and Ki value of 44 nM, which is a key signaling kinase in cancer. It displays no inhibition on c-Abl up to 125 μM and is selective between Src family members. It inhibits cell growth in 4T1 mammary carcinoma tumor cells. It has antitumor activity and may be a promising therapeutic potential in the treatment of cancers. Synonyms: 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 1380088-03-8. Molecular formula: C32H23ClN8. Mole weight: 555.03. | |
| KC01 | KC01 is an effective inhibitor of ABHD16A , with IC 50 s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646795-59-6. Pack Sizes: 1 mg. Product ID: HY-120299. | |
| KC01 | KC01 is a selective ABHD16A inhibitor (IC50s values of 90 and 520 nM for human and mouse, respectively). ABHD12 is a major brain Lysophosphatidylserine (lyso-PS) lipase. KC01 was shown to deplete lyso-PSs from cells, including the neurological disease PHARC subject-derived lymphoblasts. Synonyms: (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.6. | |
| KC01 | KC01 is a covalent inhibitor of ABHD16A. ABHD16A is a phosphatidylserine (PS) lipase that generates lyso-PS in mammalian systems. KC01 can deplete lysoPSs from cells, including lymphoblasts derived from subjects with PHARC. Group: Inhibitors. Alternative Names: KC01; K C01; K-C01. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.56. Appearance: Solid powder. Purity: >98%. IUPACName: (Z)-6-(2-oxo-4-tridecyloxetan-3-ylidene)hexanamide. Canonical SMILES: O=C (N)CCCC/C=C1C (OC\1CCCCCCCCCCCCC)=O. Catalog: ACM1646795596. | |
| KC02 | KC02 is an inactive control probe for KC01, the inhibitor of ABHD16A. Synonyms: 6-(2-Oxo-4-phenethyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-60-9. Molecular formula: C17H21NO3. Mole weight: 287.4. | |
| KC 12291 hydrochloride | KC 12291 hydrochloride is the hydrochloride salt of KC 12291, which is an orally active atypical inhibitor of voltage-gated sodium channels in ischemia. It inhibits sustained sodium currents and delays myocardial sodium overload, thus prevents diastolic contracture in isolated atria in vitro. It shows bradycardic, cardioprotective and anti-ischemic activity in vivo. Synonyms: KC 12291 hydrochloride; KC12291 hydrochloride; KC-12291 hydrochloride; 3,4-Dimethoxy-N-methyl-N-[3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propyl]benzeneethanamine hydrochloride. Grades: ≥97% by HPLC. CAS No. 181936-98-1. Molecular formula: C22H28N3O3SCl. Mole weight: 449.99. | |
| KC 12291 hydrochloride | KC 12291 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 181936-98-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KC7F2 | KC7F2 is a selective HIF-1α transcription inhibitor with IC50 of 20 μM in a cell-based assay. Synonyms: KC7f2; 927822-86-4; UNII-94C2DMM81LN, N'- (disulfanediylbis (ethane-2, 1-diyl) ) bis (2, 5-dichlorobenzenesulfonamide) 2, 5-dichloro-N- [2- [2- [ (2, 5-dichlorophenyl) sulfonylamino] ethyldisulfanyl] ethyl] benzenesulfonamide. Grades: 98%. CAS No. 927822-86-4. Molecular formula: C16H16Cl4N2O4S4. Mole weight: 570.38. | |
| KC7F2 (N,N'-(Dithiodi-2,1-ethanediyl)bis[2, 5-dichloro Benzene sulfonamide) | Inhibitor of HIF-1alpha. Thought to act via down-regulation of HIF-1alpha protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1alpha accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2. Group: Biochemicals. Grades: Highly Purified. CAS No. 927822-86-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| k-Carradecaitolpentasulfate pentasodium salt | k-Carradecaitolpentasulfate pentasodium salt is an exceptional substance unveiling an array of applications in studying multiple diseases such as influenza and the human immunodeficiency virus (HIV). Molecular formula: C60H89O61S5Na5. Mole weight: 2061.59. | |
| k-Carradiitol sulfate sodium salt | k-Carradiitol sulfate sodium salt is a renowned biomedical product, playing a pivotal role in investigating the intricacies of disease research, particularly cancer. It exhibits remarkable potency in obstructing select enzymes crucial for disease advancement. Molecular formula: C12H21O13S1Na. Mole weight: 428.34. | |
| K-Carradodecaitol-Hexasulfate Hexasodium Salt | | |
| k-Carraheptaose tetrasodium salt | k-Carraheptaose tetrasodium salt is an innovative biomedical product designed to study a multitude of diseases associated with intricate carbohydrate metabolism. It effectively augments insulin sensitivity while studying glucose uptake, showcasing its tremendous potential as a viable research for type 2 diabetes. Molecular formula: C42H62O45S4Na4. Mole weight: 1507.14. | |
| k-Carraheptaose tetrasulfate tetrasodium salt | k-Carraheptaose tetrasulfate tetrasodium salt is an exceptional biomedical substance employed for diverse maladies research, encompassing cancer, inflammation and viral infections. This compound, originating from k-Carraheptaose, unveiling formidable anti-inflammatory and antiviral attributes. Molecular formula: C42H62O45S4Na4. Mole weight: 1507.14. | |
| k-Carrahexaitol trisulfate trisodium salt | k-Carrahexaitol trisulfate trisodium salt is a paramount compound widely employed in the biomedical sector due to its remarkable and forceful antimicrobial attributes. Mechanistically, this product induces perturbation in bacterial cell wall synthesis, ultimately culminating in their complete and absolute annihilation. Molecular formula: C36H55O37S3Na3. Mole weight: 1244.97. | |
| k-Carranonaose pentasodium salt | k-Carranonaose pentasodium salt is a supremely refined compound with powerful remedial attributes. Conspicuously, it orchestrates a pivotal role in studying an array of afflictions, encompassing the formidable terrain of cancer, autoimmune disorders and inflammatory ailments. Molecular formula: C54H79O57S5Na5. Mole weight: 1915.45. | |
| k-Carranonaose pentasulfate pentasodium salt | k-Carranonaose pentasulfate pentasodium salt, a remarkable biomedical compound, showcases its efficacy in combating diverse viral infections and inflammatory ailments. With its outstanding antiviral potential, it precisely targets notorious viruses like influenza and herpes. Furthermore, this compound boasts extraordinary anti-inflammatory properties, facilitating the management of afflictions such as rheumatoid arthritis and asthma. Molecular formula: C54H79O57S5Na5. Mole weight: 1915.45. | |
| k-Carraoctaitol tetrasulfate tetrasodium salt | k-Carraoctaitol Tetrasulfate Tetrasodium Salt is a biomedical compound, showcasing profound anticoagulant attributes. Molecular formula: C48H72O49S4Na4. Mole weight: 1653.28. | |
| k-Carrapentaose trisodium salt | k-Carrapentaose trisodium salt is a biomedical product commonly used in the research of gastrointestinal disorders. Derived from natural carrageenan, it exhibits excellent anti-inflammatory properties and aids in the research of chronic inflammatory bowel diseases such as ulcerative colitis. Molecular formula: C30H45O33S3Na3. Mole weight: 1098.83. | |
| k-Carrapentaose trisulfate trisodium salt | k-Carrapentaose trisulfate trisodium salt, a state-of-the-art biomedical compound, demonstrates remarkable therapeutic potential in addressing inflammation-related conditions. Originating from marine algae, this product functions as an influential anti-inflammatory factor, specifically targeting ailments like rheumatoid arthritis and inflammatory bowel disease. Distinguished by its exceptional molecular arrangement, it presents heightened durability and extended effectiveness, positioning it as an auspicious contender for forthcoming pharmaceutical interventions. Molecular formula: C30H45O33S3Na3. Mole weight: 1098.83. | |
| k-Carratetraitol disulfate disodium salt | k-Carratetraitol disulfate disodium salt is an influential suppressor within the biomedical domain, catering to study select pharmaceuticals and ailments. It can skillfully obstruct the action of distinct enzymes consequential to cellular growth and inflammatory response. Molecular formula: C24H38O25S2Na2. Mole weight: 836.66. | |
| k-Carratriose disodium salt | k-Carratriose disodium salt is a bioactive compound extensively employed in research of ailments, encompassing cancer and diabetes. By impeding precise cellular pathways implicated in the advancement and genesis of such maladies, it exerts an inhibitory effect. Molecular formula: C18H28O21S2Na2. Mole weight: 690.51. | |
| k-Carratriose disulfate disodium salt | k-Carratriose disulfate disodium salt is an invaluable biomedical product, aiding in studying intricate inflammatory maladies like rheumatoid arthritis. Molecular formula: C18H28O21S2Na2. Mole weight: 690.51. | |
| KCC 07 | KCC 07 is an MBD2 (Methyl-CpG-binding domain protein 2) inhibitor that prevents binding of MBD2 to methylated DNA and reactivates ADGRB1 expression. Synonyms: 3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol. Grades: ≥98% by HPLC. CAS No. 315702-75-1. Molecular formula: C14H11N3OS. Mole weight: 269.32. | |
| KCN1 | KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF reporter gene activity in several glioma cell lines at the nanomolar level. KCN1 also downregulated transcription of endogenous HIF-1 target genes, such as VEGF, Glut-1, and carbonic anhydrase 9, in a hypoxia-responsive element (HRE)-dependent manner. KCN1 potently inhibited the growth of subcutaneous malignant glioma tumor xenografts with minimal adverse effects on the host. Mechanistically, KCN1 did not downregulate the levels of HIF-1α or other components of the HIF transcriptional complex; rather, it antagonized hypoxia-inducible transcription by disrupting the interaction of HIF-1α with transcriptional coactivators p300/CBP.CONCLUSIONS: The new HIF pathway inhibitor KCN1 has antitumor activity in mouse models, supporting its further translation for the treatment of human tumors displaying hypoxia or HIF overexpression. Synonyms: KCN-1; 3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide. CAS No. 927823-01-6. Molecular formula: C26H27NO5S. Mole weight: 465.561. | |
| KD025 | KD025 is an orally available and selective ROCK2 inhibitor with IC50 value of 60 nM and Ki value of 41 nm, respectively. It was shown to suppress adipogenesis in human adipose-derived stem cells. Uses: Protein kinase inhibitors. Synonyms: SLx 2119; SLx2119; KD-025; 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide. Grades: >98%. CAS No. 911417-87-3. Molecular formula: C26H24N6O2. Mole weight: 452.51. | |
| K-(D-1-Nal)-FwLL-NH2 | K-(D-1-Nal)-FwLL-NH2 is a potent and high affinity inverse ghrelin receptor inverse agonist. Its Ki values are 31 and 4.9 nM in HEK293T and COS7 cells respectively. It blocks ghrelin receptor-mediated G13- and Gq-dependent signaling pathways. Synonyms: L-Lysyl-3-(1-naphthalenyl)-D-alanyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide; K-(D-1-Nal)-FwLL-NH2; K (D 1 Nal) FwLL NH2. Grades: >98%. CAS No. 1394288-22-2. Molecular formula: C51H67N9O6. Mole weight: 902.13. | |
| KD 5170 | KD 5170 is a mercaptoketone-based histone deacetylase (HDAC) inhibitor displaying antitumor activity in vitro and in vivo. It exhibits broad spectrum antitumor activity in vitro and in vivo. Synonyms: S- (2- (6- (4- (3- (Dimethylamino) propoxy) phenylsulfonamido) pyridin-3-yl) -2-oxoethyl) ethanethioate. Grades: ≥98%. CAS No. 940943-37-3. Molecular formula: C20H25N3O5S2. Mole weight: 451.6. | |
| KD 5170 | KD 5170. Group: Biochemicals. Grades: Purified. CAS No. 940943-37-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| KDAMP | HGAPDH is a cationic peptide isolated from Homo sapiens. It has activity against gram-negative bacteria. Synonyms: KDAMP 19-mer; H-Arg-Ala-Ile-Gly-Gly-Gly-Leu-Ser-Ser-Val-Gly-Gly-Gly-Ser-Ser-Thr-Ile-Lys-Tyr-al. Grades: 95.4%. Molecular formula: C75H127N23O25. Mole weight: 1751.0. | |
| KDM4D-IN-1 | A novel histone lysine demethylase 4D (KDM4D) inhibitor (IC50= 0.41±0.03 μM). Synonyms: KDM4D-IN-1; KDM4D IN 1. CAS No. 2098902-68-0. Molecular formula: C11H7N5O. Mole weight: 225.21. | |
| KDM5A-IN-1 | KDM5A-IN-1, a pyrrolidine amide compound, is an inhibitor histone demethylases. Synonyms: KDM5A-IN-1; KDM5A IN 1; KDM5AIN1; KDM5A inhibitor-1; KDM5A inhibitor 1; N-[(3R)-1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]cyclopropanecarboxamideKDM5A-IN-1. CAS No. 1905481-36-8. Molecular formula: C15H22N4O2. Mole weight: 290.36. | |
| KDM5-IN-1 | KDM5-IN-1 is a potent and selective KDM5 inhibitor with modest cell activity (PC9 H3K4Me3 EC50 = 5.2 μM). Synonyms: KDM5-IN-48; KDM5 IN 48; KDM5IN48; KDM5 inhibitor-48; KDM5 inhibitor 48; 5-(1-tert-butylpyrazol-4-yl)-7-oxo-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile. CAS No. 1628210-26-3. Molecular formula: C17H20N6O. Mole weight: 324.38. | |
| KDM5-inhibitor | KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells. Synonyms: KDM5 inhibitor; 7-oxo-5-phenyl-6-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Molecular formula: C16H14N4O. Mole weight: 278.315. | |
| Kdo2-Lipid A ((3-Deoxy-D-manno-octulosonic acid)2-Lipid A) | Defined substructure of the Re mutant of lipopolysaccharide (LPS). Strong activator (<10ng/ml) of toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Source:Isolated and purified from E. coli K12 heptose-deficient strain WBB06 (Re mutant) [1] by a modification of the PCP extraction method [2,3], converted to the uniform sodium salt form [4] and dissolved in sterile pyrogen-free double distilled water. Group: Biochemicals. Alternative Names: (3-Deoxy-D-manno-octulosonic acid)2-Lipid A. Grades: Purified. CAS No. 123621-04-5 (free base). Pack Sizes: 1mg. Molecular Formula: C110H198N2Na4O39P2, Molecular Weight: 2326.7. US Biological Life Sciences. | Worldwide |
| Kdo2-Lipid A ammonium | Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 1246298-62-3. Pack Sizes: 1 mg. Product ID: HY-N8277. | |
| Kdo2-Lipid A (KLA) | Bioactive Lipids. Alternative Names: Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt); KLA. CAS No. 1246298-62-3. Mole weight: 2306.84. Appearance: Powder. Purity: >95%. Catalog: ACM1246298623. | |
| Kdo2-Lipid A (KLA) | Kdo2-Lipid A (KLA) is a potent immunostimulatory compound used in biomedical field. It activates immune cells via Toll-like receptor 4 (TLR4), triggering cytokine production and enhancing immune responses. This product aids in the study of immune regulation and the development of vaccines and therapeutics targeting infectious diseases, cancer and inflammation. Synonyms: Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt). Grades: >95%. CAS No. 1246298-62-3. Molecular formula: C110H202N2O39P2.4NH3. Mole weight: 2415.69. | |
| Kdo2-lipid A phosphoethanolamine 7''-transferase | The enzyme has been characterized from the bacterium Escherichia coli. It is activated by Ca2+ ions and is is silenced by the sRNA MgrR. Group: Enzymes. Synonyms: eptB (gene name). Enzyme Commission Number: EC 2.7.8.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3342; Kdo2-lipid A phosphoethanolamine 7''-transferase; EC 2.7.8.42; eptB (gene name). Cat No: EXWM-3342. | |
| Kdo2-lipid A phosphotransferase | An inner-membrane protein. The activity of the enzyme is regulated by PmrA. In vitro the enzyme can use diacylglycerol 3-diphosphate as the phosphate donor. Group: Enzymes. Synonyms: lipid A undecaprenyl phosphotransferase; LpxT; YeiU. Enzyme Commission Number: EC 2.7.4.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3211; Kdo2-lipid A phosphotransferase; EC 2.7.4.29; lipid A undecaprenyl phosphotransferase; LpxT; YeiU. Cat No: EXWM-3211. | |
| Kdo2-lipid IVA lauroyltransferase | The enzyme, characterized from the bacterium Escherichia coli, is involved in the biosynthesis of the phosphorylated outer membrane glycolipid lipid A. Group: Enzymes. Synonyms: LpxL; htrB (gene name); dodecanoyl-[acyl-carrier protein]:α-Kdo-(2?4)-α-Kdo-(2?6)-lipid IVA O-dodecanoyltransferase; lauroyl-[acyl-carrier protein]:Kdo2-lipid IVA O-lauroyltransferase; (Kdo)2-lipid IVA lauroyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA lauroyltransferase. Enzyme Commission Number: EC 2.3.1.241. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2190; Kdo2-lipid IVA lauroyltransferase; EC 2.3.1.241; LpxL; htrB (gene name); dodecanoyl-[acyl-carrier protein]:α-Kdo-(2?4)-α-Kdo-(2?6)-lipid IVA O-dodecanoyltransferase; lauroyl-[acyl-carrier protein]:Kdo2-lipid IVA O-lauroyltransferase; (Kdo)2-lipid IVA lauroyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA lauroyltransferase. Cat No: EXWM-2190. | |
| Kdo2-lipid IVA palmitoleoyltransferase | The enzyme, characterized from the bacterium Escherichia coli, is induced upon cold shock and is involved in the formation of a cold-adapted variant of the outer membrane glycolipid lipid A. Group: Enzymes. Synonyms: LpxP; palmitoleoyl-acyl carrier protein-dependent acyltransferase; cold-induced palmitoleoyl transferase; palmitoleoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase; (Kdo)2-lipid IVA palmitoleoyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA palmitoleoyltransferase. Enzyme Commission Number: EC 2.3.1.242. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2191; Kdo2-lipid IVA palmitoleoyltransferase; EC 2.3.1.242; LpxP; palmitoleoyl-acyl carrier protein-dependent acyltransferase; cold-induced palmitoleoyl transferase; palmitoleoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase; (Kdo)2-lipid IVA palmitoleoyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA palmitoleoyltransferase. Cat No: EXWM-2191. | |
| Kdo azide | CuAAC & SPAAC Click Reactions. Group: Azides. CAS No. 1380099-68-2. Molecular formula: C8H16N4O7. Mole weight: 280.24. Appearance: Solid. Purity: 99%+. Catalog: CCR1380099682. | |
| KD Plus DNA Polymerase | KD Plus DNA Polymerase. Kd plus dna polymerase is a genetically modified high fidelity dna polymerase. this enzyme provides higher amplification capability than traditional pfu dna polymerase and fast amplification speed equal to taq dna polymerase (1 kb/min). due to strong 3-5 exonuclease activity, this enzyme offers 108-fold fidelity as compared to taq dna polymerase. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 100U; 200U. Storage: Store at -20 ?. Cat No: CE-3019. | |
| KDR-in-4 | A potent kinase insert domain-containing receptor (KDR/VEGFR2) inhibitor (IC50= 7 nM). Synonyms: 3-[5-[2-[2-methoxyethyl(methyl)amino]ethoxy]-1H-indol-2-yl]-1H-quinolin-2-one. CAS No. 408502-06-7. Molecular formula: C23H25N3O3. Mole weight: 391.46. | |
| KDU691 | KDU691 is a plasmodium PI4K inhibitor (IC50 values of 0.18 μM and 0.061 μM against hypnozoite forms and liver schizontsm, respectively) that inhibits dihydroartemisinin-pretreated plasmodium falciparum ring-stage parasites. Synonyms: KDU691; KDU-691; KDU 691; HY-12912; HY 12912; HY12912; N-(4-chlorophenyl)-N-methyl-3-[4-(methylcarbamoyl)phenyl]imidazo[1,2-a]pyrazine-6-carboxamide. Grades: 98%. CAS No. 1513879-19-0. Molecular formula: C22H18ClN5O2. Mole weight: 419.86. | |
| KDU-731 | KDU-731 is a selective inhibitor of Cryptosporidium lipid kinase PI(4)K over human PI(4)K. It exhibits potential cardiotoxicity, mutagenicity, clastogenicity or phototoxicity. KDU-731 is a new treatment for pediatric diarrhea caused by the parasite Cryptosporidium. Uses: Pediatric diarrhea caused by the parasite cryptosporidium. Synonyms: KDU 731; KDU731. CAS No. 1610610-48-4. Molecular formula: C22H16N6O2. Mole weight: 396.40. | |
| Kebuzone | Kebuzone is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory activities. Kebuzone is a cyclooxygenase inhibitor. It can block the synthesis of prostaglandins by inhibiting cyclooxygenase. Uses: Non-steroidal anti-inflammatory drug. Synonyms: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-4-(2-acetylethyl) pyrazolidine-3,5-dione; Chebutan; Chepirol; Chetazol; Chetazolidin; Chetil; Chetopir; Copirene; Ejor; Gammachetone; KPB; Ketanol; Ketason; Ketazon; Ketazone; Ketophenylbutazone; Pecnon; Phloguron; Recheton; Reuchetal; γ-Ketazone; γ-Ketophenylbutazone; γ-Oxophenylbutazone. Grades: 98%. CAS No. 853-34-9. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
| Kebuzone | Kebuzone. Group: Biochemicals. Alternative Names: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedion. Grades: Highly Purified. CAS No. 853-34-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C19H18N2O3. US Biological Life Sciences. | Worldwide |
| Kebuzone | Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketazone; Ketophenylbutazone. CAS No. 853-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111284. | |
| Kedarcidin | Heterocyclic Organic Compound. CAS No. 128512-39-0. Catalog: ACM128512390. | |
| KEL-FIM-FAME mixture-5 | KEL-FIM-FAME mixture-5. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Synthetic or plant. KEL-FIM-FAME mixture-5; GC; KEL-FIM-FAME-5 Mixture (Methyl ester mixture); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-107. | |
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