A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
H10 is a potent and cell-active PARP14 inhibitor (IC50 = 490 nM), which exhibits ~ 24- and 18-fold selectivity for PARP14 over PARP1 and TNKS1, respectively. Synonyms: 3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid. Grades: ≥98% by HPLC. CAS No. 2084811-68-5. Molecular formula: C24H27N7O7S. Mole weight: 557.58.
H 1152 dihydrochloride
H 1152 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 871543-07-6. Pack Sizes: 1mg. US Biological Life Sciences.
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H-1152 Dihydrochloride
H-1152 Dihydrochloride is a cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. It inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. It selectively blocks lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC50=2.5nM) in NT-2 cells. Synonyms: (S) - (+) -2-Methyl-1-[ (4-methyl-5-isoquinolynyl) sulfonyl]homopiperazine Dihydrochloride;5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline dihydrochloride;4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrochloride. Grades: >98 %. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34.
H-1152 Dihydrochloride
H-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1.6 nM, and an IC50 value of 12 nM for ROCK2. Group: Inhibitors. Alternative Names: 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34. Appearance: White to Off-White Solid. Catalog: ACM871543076.
H-1152 Dihydrochloride
H-1152 Dihydrochloride. Group: Biochemicals. Alternative Names: 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline. Grades: Highly Purified. CAS No. 871543-07-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H23Cl2N3O2S. US Biological Life Sciences.
ROCK Inhibitor. A cell-permeable isoquinolinesulfonamid e compoud that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK: Ki=1.6nM). Exhibits a much weaker affinity for other serine/. Group: Biochemicals. Alternative Names: H1152P Dihydrochloride, (S) - (+) -2-Methyl-1- [ (4-methyl-5-isoquinolynyl) sulfonyl] homopiperazine Dihydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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H-1152Glycyl dihydrochloride
H-1152Glycyl dihydrochloride. Group: Biochemicals. Alternative Names: 2-Amino-1-[ (3S) -hexahydro-3-methyl-4-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepin-1-yl]ethanone hydrochloride; (2S) -4- (Aminoacetyl) hexahydro-2-methyl-1-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepine dihydrochloride. Grades: Highly Purified. CAS No. 913844-45-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C18H26Cl2N4O3S. US Biological Life Sciences.
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H-1152 Glycyl Dihydrochloride
A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis. Group: Biochemicals. Alternative Names: 2-Amino-1-[ (3S) -hexahydro-3-methyl-4-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepin-1-yl]ethanone Hydrochloride; (2S) -4- (Aminoacetyl) hexahydro-2-methyl-1-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepine Dihydrochloride. Grades: Highly Purified. CAS No. 913844-45-8. Pack Sizes: 1mg. US Biological Life Sciences.
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H-1,3-cis-ACHC-OMe·HCl
H-1,3-cis-ACHC-OMe·HCl. Group: Biochemicals. Alternative Names: H-1,3-cis-ACHC-OMe·HCl. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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H-1,3-cis-ACHC-OMe·HCl 99+% (
H-1,3-cis-ACHC-OMe·HCl 99+% (. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
H-1,4-trans-Achc-OMe·HCl 99+% (. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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H 151
H 151 is a highly potent, selective STING antagonist, which reduces TBK1 phosphorylation and suppresses human STING palmitoylation. Synonyms: H-151; H151; Urea, N-(4-ethylphenyl)-N'-1H-indol-3-yl-; N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea; N-(4-Ethylphenyl)-N'-1H-indol-3-ylurea; H 151 (pharmacological agent). Grades: ≥98%. CAS No. 941987-60-6. Molecular formula: C17H17N3O. Mole weight: 279.34.
H1N1 Liposome
This liposome contains H1N1 and can be used for influenza. It is only for research purposes. Group: Liposomal vaccine or adjuvant. Categories: H1N1 Liposome.
Renewable & Alternative Energy. Alternative Names: 2,2μ-Dinitro-4,4μ-stilbenedicarboxylic acid;H2DNSDC. CAS No. 1202689-44-8. Catalog: ACM1202689448.
H2-Gamendazole
Gamendazole. CAS No. 877768-84-8.
Pennsylvania PA
H2L5186303
H2L5186303. Group: Biochemicals. Grades: Purified. CAS No. 139262-76-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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H2L5186303
H2L5186303 is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 = 8.9, 1230 and 27354 nM for LPA2, LPA3 and LPA1 receptors respectively, in a LPA-elicited calcium mobilization assay). Synonyms: H2L5186303; H2L 5186303; H2L-5186303; (Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid. Grades: ≥98% by HPLC. CAS No. 139262-76-3. Molecular formula: C26H20N2O8. Mole weight: 488.45.
H2L 5765834
H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 = 94, 463 and 752 nM, respectively). H2L 5765834 may be used for the treatment of systemic sclerosis. Uses: Potential treatment of systemic sclerosis. Synonyms: H2L 5765834; H2L5765834; H2L-5765834; 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid; 2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxoisoindole-5-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 420841-84-5. Molecular formula: C21H12N2O7. Mole weight: 404.33.
H2L 5765834
H2L 5765834. Group: Biochemicals. Grades: Purified. CAS No. 420841-84-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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H-2-Me-DL-Ser-OH
. Uses: A serine derivative. used in the synthesis of constrained amino acid buildings blocks and their incorporation into biologically active peptidomimetics. Synonyms: H-DL-aMeSer-OH; alpha-Methyl-DL-serine; DL-2-Methylserine; 2-Methylserine; H-alpha-Me-DL-Ser-OH; H alpha Me DL Ser OH; H 2 Me DL Ser OH. Grades: 95%. CAS No. 5424-29-3. Molecular formula: C4H9NO3. Mole weight: 119.12.
H-2-Me-D-Ser-OH
. Uses: A potential chiral building blocks for the synthesis of different α -methyl α -amino acids. Synonyms: H-D-aMeSer-OH; 2-Methyl-D-serine; H-alpha-Me-D-Ser-OH; H alpha Me D Ser OH; H 2 Me D Ser OH. Grades: 98%. CAS No. 81132-44-7. Molecular formula: C4H9NO3. Mole weight: 119.12.
H-7 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 108930-17-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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H-7 dihydrochloride
H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively). H-7 inhibits cell invasion and metastasis in B16BL6 cancer cells through the PKC/MEK/ERK pathway. It was also shown to inhibit Topo I and II in murine L929 cells and induce apoptosis via PKC inhibition. Synonyms: H7 dihydrochloride; H7 HCl. (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 108930-17-2. Molecular formula: C14H17N3O2S.2HCl. Mole weight: 364.29.
Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM. Synonyms: Protein kinase inhibitor H-89; H89; H 89. Grades: >98%. CAS No. 127243-85-0. Molecular formula: C20H20BrN3O2S. Mole weight: 446.36.
H 89 2HCl
H 89 2HCl is a cell permeable and potent PKA inhibitor with Ki of 48 nM in a cell-free assay, wihich is 10-fold selective for PKA than PKG, 500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. Synonyms: N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 130964-39-5. Molecular formula: C20H20BrN3O2S·2HCl. Mole weight: 519.28.
H 89 dihydrochloride
H 89 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130964-39-5. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
H-89 dihydrochloride (N-5-isoquinolinesulfonamid e . 2HCl)
Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Protein kinase Cµ (PKCµ) inhibitor. Ca2+/calmodulin-dependent protein kinase II inhibitor. Casein kinase I inhibitor. Myosin light chain kinase (MLCK) inhibitor. Apoptosis enhancer. Tool to study protein crystal structure-inhibitor interactions. Rho kinase inhibitor. Cell proliferation inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 127243-85-0. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H20BrN3O2S. 2HCl, Molecular Weight: 519.3. US Biological Life Sciences.
Worldwide
H-89 Dihydrochloride (PKA Inhibitor III, N- [2- ( (p-Bromocinnamyl ) amino) ethyl ]-5-isoquinolinesulfonamid e , 2HCl)
A cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase A (Ki = 48nM). Inhibits other kinases only at much higher concentrations: CaM kinase II (Ki = 29.7uM), casein kinase I (Ki = 38.3uM), myosin light chain kinase (Ki = 28.3uM), protein kinase C (Ki = 31.7uM), and ROCK-II (IC50 = 270nM). May be used to discriminate between the effects of PKA and cAMP-regulated guanine-nucleotide-exchange factors (GEFs) such as GEFI, GEFII, or Epac (exchange protein directly activated by cAMP). Enhances radiation-induced apoptosis in the human cell line BM 13674. Group: Biochemicals. Grades: Highly Purified. CAS No. 127243-85-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
H-8 dihydrochloride
Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Myosin light chain kinase (MLCK) inhibitor. Tool to study protein crystal structure-inhibitor interactions. Group: Biochemicals. Grades: Highly Purified. CAS No. 113276-94-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C12H15N3O2S 2HCl. US Biological Life Sciences.
Worldwide
H-8 dihydrochloride
H-8 is a cell-permeable and potent inhibitor of PKA and PKG with Ki values of 1.2 and 0.48 μM, respectively. It also slightly inhibits PKC and MLCK with Ki values of 15 and 68 μM. Synonyms: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 113276-94-1. Molecular formula: C12H15N3O2S·2HCl. Mole weight: 338.3.
H-9 dihydrochloride is a protein kinase inhibitor. It inhibits PKA (Ki = 1.9 μM), PKG (Ki = 0.9 μM), CaMK II (Ki = 60 μM), PKC (Ki = 18 μM), casein kinase I (Ki = 110 μ M) and casein kinase II (Ki > 300 μM). H-9 hydrochloride reduces the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons2 and inhibits PKA-mediated phosphorylation in a rat seizure model. Synonyms: H-9 dihydrochloride; H 9 dihydrochloride; H9 dihydrochloride; N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥99% by HPLC. CAS No. 116700-36-8. Molecular formula: C11H13N3O2S.2HCl. Mole weight: 324.22.
H-9 dihydrochloride
H-9 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 116700-36-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
H-9 Dihydrochloride
Heterocyclic Organic Compound. Alternative Names: H-9 DIHYDROCHLORIDE;H-9;N-(2-AMINOETHYL)ISOQUINOLINE-5-SULPHONAMIDE DIHYDROCHLORIDE;N-(2-AMINOETHYL)-5-ISOQUINOLINESULFONAMIDE 2HCL;N-(2-AMINOETHYL)-5-ISOQUINOLINESULFONAMIDE DIHYDROCHLORIDE;N-(2-aminoethyl)-5-isoquinoline-*sulfonamide hydr. CAS No. 116700-36-8. Molecular formula: C11H15Cl2N3O2S. Mole weight: 324.23. Appearance: White Crystalline Solid. Catalog: ACM116700368.
HA-1004 dihydrochloride
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:2); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, dihydrochloride; HA 1004 dihydrochloride; HA1004 dihydrochloride; N-(2-guanidinoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 92564-08-4. Molecular formula: C12H15N5O2S.2HCl. Mole weight: 366.27.
HA-100 Dihydrochloride
HA-100 Dihydrochloride. Group: Biochemicals. Alternative Names: AGN-PC-00L2ST, SCHEMBL5176161, 1-(5-ISOQUINOLINESULFONYL)-PIPERAZINE. Grades: Highly Purified. CAS No. 210297-47-5. Pack Sizes: 25mg. Molecular Formula: C13 H15 N3O2, Molecular Weight: 350.3. US Biological Life Sciences.
Worldwide
HA-1077 dihydrochloride
HA-1077 is a potent and selective inhibitor of Rho kinase (ROCK). HA-1077 exhibited neuroprotective effects and enhanced cognition in mouse models of amyotrophic lateral sclerosis (ALS), suggesting its potential use for cognitive disorders such as ALS, Alzheimer's disease and spinal muscular atrophy. It also suppresses tumor cell motility and metastasis. Synonyms: Fasudil dihydrochloride; 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride. Grades: ≥98%. CAS No. 203911-27-7. Molecular formula: C14H17N3O2S·2HCl. Mole weight: 364.3.
HA1077 (Fasudil Dihydrochloride)
A potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced contraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho-associated Kinase (ROCK).HA1077 is an inhibitor of ROK/ROCK II (IC50 1.9uM), PRK2 (IC50 4uM), MSK1 (IC50 5uM), Rsk2 (IC50 15uM), PKA, p70 S6 Kinase, CaM Kinase (Ki 1.8nM) and MLCK (Ki 20nM). HA1077 is a calcium antagonist and has antivasospastic properties. Inhibits ROKa/ROCK II, PRK2, MSK1, Rsk2, PKA, p70 S6 Kinase, CaM Kinase and MLCK. Group: Biochemicals. Alternative Names: Fasudil Dihydrochloride; 1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine 2HCl; 1-(5-Isoquinolinesulfonyl) homopiperazine 2HCl). Grades: Highly Purified. CAS No. 103745-39-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C14H17N3O2S 2HCl, Molecular Weight: 364.29. US Biological Life Sciences.
Worldwide
HA 1100 hydrochloride
HA 1100 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 155558-32-0. Pack Sizes: 10mg. US Biological Life Sciences.
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HA 130
HA 130. Group: Biochemicals. Grades: Purified. CAS No. 1229652-21-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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HA-130
HA-130, an effective autotaxin (ATX) inhibitor, has been found to restrain the cell migration related to ATX in in an A2058 melanoma cells. IC50: 28 nM. Uses: Ha-130 is an effective autotaxin (atx) inhibitor that has been found to restrain the cell migration related to atx in in an a2058 melanoma cells. Synonyms: SCHEMBL1555945; 1229652-21-4; HA130; HA-130; HA 130. Grades: >98 %. CAS No. 1229652-21-4. Molecular formula: C24H19BFNO5S. Mole weight: 463.29.
HA14-1
HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. HA14-1 suppressed NF-kappaB activation through inhibition of phosphorylation and degradation of IkappaBalpha. Synonyms: HA-141, HA 141, HA141. CAS No. 65673-63-4. Molecular formula: C17H17BrN2O5. Mole weight: 409.23.
HA14-1
HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. HA14-1 suppressed NF-kappaB activation through inhibition of phosphorylation and degradation of IkappaBalpha. This inhibition was correlated with suppression of NF-kappaB-dependent gene products (c-myc, cyclin D1, cox-2, and IAP-1). Additionally, HA14-1 also markedly sustained TNF-alpha-mediated JNK activation. Group: Inhibitors. Alternative Names: HA-141, HA 141, HA141. CAS No. 65673-63-4. Molecular formula: C17H17BrN2O5. Mole weight: 409.24. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-ethyl 2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate. Canonical SMILES: O=C (C1=C (N)OC2=C (C=C (Br)C=C2)[C@H]1[C@H] (C#N)C (OCC)=O)OCC. Catalog: ACM65673634.
HA14-1
HA14-1. Group: Biochemicals. Grades: Purified. CAS No. 65673-63-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Ha-15
HA-15 is a compound that targets BiP/GRP78/HSPA5 with an antitumor activity on all melanoma cells. Uses: Ha-15 is a compound that targets bip/grp78/hspa5 with an antitumor activity. Synonyms: HA15; HA 15; N-(4-(3-((5-(dimethylamino)naphthalene)-1-sulfonamido)phenyl)thiazol-2-yl)acetamide. Grades: ≥98%. CAS No. 1609402-14-3. Molecular formula: C23H22N4O3S2. Mole weight: 466.574.
HA 150
HA 150. Group: Biochemicals. Alternative Names: B- [3- [ [4- [ [3- [ (4-Fluorophenyl) methyl] -2, 4-dioxo-5-thiazolidinylidene] methyl] phenoxy] methyl] phenyl] boronic acid. Grades: Highly Purified. CAS No. 1229652-21-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C24H19BFNO5S. US Biological Life Sciences.
Worldwide
HA-155
HA-155 is an autotaxin inhibitor. Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (NPP2 or ENPP2), is a secreted enzyme converting lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), which is responsible for tumor cell motility stimulation. Synonyms: HA 155; HA155; Autotaxin Inhibitor IV; Boronic acid, B- [4- [ [4- [ [3- [ (4-fluorophenyl) methyl] -2, 4-dioxo-5-thiazolidinylidene] methyl] phenoxy] methyl] phenyl] -. Grades: ≥95%. CAS No. 1229652-22-5. Molecular formula: C24H19BFNO5S. Mole weight: 463.3.
HaA4
Among the synthetic homodimer peptide analogues derived from harmoniasin, HaA4 has been found to have antibacterial activity without hemolytic activity.
HabaNero Pepper Mesquite Smoked
The name HabaNero means Havana, a reference to the heat the Republican Party gets whenever it takes on Fidel Castro! Actually, the name refers to the possibility that its origin emanates more from the Caribbean than South America and the Yucatan Peninsula. Group: Molecular Biology. Alternative Names: Capsicum Annuum; Chinense; Goat Pepper; Scotch BonnetCongo Pepper; Fish Eye; Blowgun Pepper. Grades: Molecular Biologist Grade. CAS No. Pack Sizes: 14g. US Biological Life Sciences.
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Habanolide®
Habanolide®. CAS No. 111879-80-2. Kosher: Y. VIGON Item # 502795. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.