A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
H10 is a potent and cell-active PARP14 inhibitor (IC50 = 490 nM), which exhibits ~ 24- and 18-fold selectivity for PARP14 over PARP1 and TNKS1, respectively. Synonyms: 3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid. Grade: ≥98% by HPLC. CAS No. 2084811-68-5. Molecular formula: C24H27N7O7S. Mole weight: 557.58.
H100
H100, a Cl- transport inhibitor on membrane transport pathways in human eythrocytes, has partial effects against both the NaK2Cl cotransporter (NKCC) and the Band 3 anion exchanger (AE), but no effect against KCl cotransporter (KCC). Synonyms: H 100; 3-(Aminosulfonyl)-4-(4-methoxyphenoxy)-5-(1H-pyrrol-1-yl)benzoic Acid; 4-(4-Methoxyphenoxy)-3-(1H-pyrrol-1-yl)-5-sulfamoylbenzoic acid; Benzoic acid, 3-(aminosulfonyl)-4-(4-methoxyphenoxy)-5-(1H-pyrrol-1-yl)-. Grade: ≥95%. CAS No. 643727-55-3. Molecular formula: C18H16N2O6S. Mole weight: 388.39.
H 1152 dihydrochloride
H 1152 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 871543-07-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
H-1152 dihydrochloride
H-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1.6 nM, and an IC50 value of 12 nM for ROCK2. Uses: Scientific research. Group: Signaling pathways. CAS No. 871543-07-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15720A.
H-1152 Dihydrochloride
H-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1.6 nM, and an IC50 value of 12 nM for ROCK2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline. Product Category: Inhibitors. Appearance: White to Off-White Solid. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34. Product ID: ACM871543076. Alfa Chemistry ISO 9001:2015 Certified.
H-1152 Dihydrochloride
H-1152 Dihydrochloride is a cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. It inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. It selectively blocks lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC50=2.5nM) in NT-2 cells. Synonyms: (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolynyl)sulfonyl]homopiperazine Dihydrochloride; 5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline dihydrochloride; 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrochloride. Grade: >98 %. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34.
H-1152 Dihydrochloride
H-1152 Dihydrochloride. Group: Biochemicals. Alternative Names: 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline. Grades: Highly Purified. CAS No. 871543-07-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H23Cl2N3O2S. US Biological Life Sciences.
ROCK Inhibitor. A cell-permeable isoquinolinesulfonamid e compoud that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK: Ki=1.6nM). Exhibits a much weaker affinity for other serine/. Group: Biochemicals. Alternative Names: H1152P Dihydrochloride, (S) - (+) -2-Methyl-1- [ (4-methyl-5-isoquinolynyl) sulfonyl] homopiperazine Dihydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
H-1152Glycyl dihydrochloride
H-1152Glycyl dihydrochloride. Group: Biochemicals. Alternative Names: 2-Amino-1-[ (3S) -hexahydro-3-methyl-4-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepin-1-yl]ethanone hydrochloride; (2S) -4- (Aminoacetyl) hexahydro-2-methyl-1-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepine dihydrochloride. Grades: Highly Purified. CAS No. 913844-45-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C18H26Cl2N4O3S. US Biological Life Sciences.
Worldwide
H-1152 Glycyl Dihydrochloride
A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis. Group: Biochemicals. Alternative Names: 2-Amino-1-[ (3S) -hexahydro-3-methyl-4-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepin-1-yl]ethanone Hydrochloride; (2S) -4- (Aminoacetyl) hexahydro-2-methyl-1-[ (4-methyl-5-isoquinolinyl) sulfonyl]-1H-1, 4-diazepine Dihydrochloride. Grades: Highly Purified. CAS No. 913844-45-8. Pack Sizes: 1mg. US Biological Life Sciences.
H-1,4-trans-Achc-OMe·HCl 99+% (. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
H 151
H 151 is a highly potent, selective STING antagonist, which reduces TBK1 phosphorylation and suppresses human STING palmitoylation. Synonyms: H-151; H151; Urea, N-(4-ethylphenyl)-N'-1H-indol-3-yl-; N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea; N-(4-Ethylphenyl)-N'-1H-indol-3-ylurea; H 151 (pharmacological agent). Grade: ≥98%. CAS No. 941987-60-6. Molecular formula: C17H17N3O. Mole weight: 279.34.
H-151
H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 941987-60-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112693.
H-[15n]Leu-oh
H-[15n]Leu-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-Leucine-15N, 59935-31-8. Product Category: Heterocyclic Organic Compound. CAS No. 59935-31-8. Molecular formula: C6H13NO2. Mole weight: 132.18. Purity: 0.96. IUPACName: (2S)-2-azanyl-4-methylpentanoic acid. Canonical SMILES: CC(C)CC(C(=O)O)N. Product ID: ACM59935318. Alfa Chemistry ISO 9001:2015 Certified.
H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate. CAS No. 4091-99-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0940.
h2Dnsdc
h2Dnsdc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,2μ-Dinitro-4,4μ-stilbenedicarboxylic acid;H2DNSDC. Product Category: Renewable & Alternative Energy. CAS No. 1202689-44-8. Product ID: ACM1202689448. Alfa Chemistry ISO 9001:2015 Certified.
H2-Gamendazole
Gamendazole. CAS No. 877768-84-8.
Pennsylvania PA
H2L5186303
H2L5186303 is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 = 8.9, 1230 and 27354 nM for LPA2, LPA3 and LPA1 receptors respectively, in a LPA-elicited calcium mobilization assay). Synonyms: H2L5186303; H2L 5186303; H2L-5186303; (Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid. Grade: ≥98% by HPLC. CAS No. 139262-76-3. Molecular formula: C26H20N2O8. Mole weight: 488.45.
H2L5186303. Group: Biochemicals. Grades: Purified. CAS No. 139262-76-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
H2L 5765834
H2L 5765834. Group: Biochemicals. Grades: Purified. CAS No. 420841-84-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
H2L 5765834
H2L 5765834 is an antagonist of lysophosphatidic acid receptors LPA1, LPA3, and LPA5, with IC50s of 94, 752, and 463 nM respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 420841-84-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15706.
H2L 5765834
H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 = 94, 463 and 752 nM, respectively). H2L 5765834 may be used for the treatment of systemic sclerosis. Uses: Potential treatment of systemic sclerosis. Synonyms: H2L 5765834; H2L5765834; H2L-5765834; 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid; 2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxoisoindole-5-carboxylic acid. Grade: ≥99% by HPLC. CAS No. 420841-84-5. Molecular formula: C21H12N2O7. Mole weight: 404.33.
H-2-Me-DL-Ser-OH
H-2-Me-DL-Ser-OH. Uses: A serine derivative. used in the synthesis of constrained amino acid buildings blocks and their incorporation into biologically active peptidomimetics. Synonyms: H-DL-aMeSer-OH; alpha-Methyl-DL-serine; DL-2-Methylserine; 2-Methylserine; H-alpha-Me-DL-Ser-OH; H alpha Me DL Ser OH; H 2 Me DL Ser OH. Grade: 95%. CAS No. 5424-29-3. Molecular formula: C4H9NO3. Mole weight: 119.12.
H-2-Me-DL-Ser-OMe HCl
H-2-Me-DL-Ser-OMe HCl. Synonyms: H 2 Me DL Ser OMe HCl. CAS No. 89500-37-8. Molecular formula: C5H12ClNO3. Mole weight: 169.61.
H-2-Me-D-Ser-OH
H-2-Me-D-Ser-OH. Uses: A potential chiral building blocks for the synthesis of different α -methyl α -amino acids. Synonyms: H-D-aMeSer-OH; 2-Methyl-D-serine; H-alpha-Me-D-Ser-OH; H alpha Me D Ser OH; H 2 Me D Ser OH. Grade: 98%. CAS No. 81132-44-7. Molecular formula: C4H9NO3. Mole weight: 119.12.
H-2-Me-D-Ser-OMe HCl
H-2-Me-D-Ser-OMe HCl. Synonyms: H 2 Me D Ser OMe HCl. Molecular formula: C5H12ClNO3. Mole weight: 169.61.
H-2-Me-Ser-OMe HCl
H-2-Me-Ser-OMe HCl. Synonyms: H-2-Me-L-Ser-OMe HCl; H 2 Me L Ser OMe HCl; H 2 Me Ser OMe HCl. CAS No. 114396-63-3. Molecular formula: C5H12ClNO3. Mole weight: 169.61.
H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1122484-77-8. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-135927.
H2N-tagged Boc-PEG-resin
TentaGel resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which poly(ethylene glycol) (PEG or POE) is grafted. Synonyms: NH2-(Boc)-PEG Resin; TentaGel B Boc/NH2; H2N-tagged N-(t-Butoxycarbonyl) polyethyleneglycol resin.
H2N-tagged Fmoc-NH-SAL resin
TentaGel resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which poly(ethylene glycol) (PEG or POE) is grafted. Synonyms: NH2-(Fmoc-NH-SAL)-PEG Resin; TentaGel B RAM/NH2; H2N-tagged N-(9-Fluorenylmethoxycarbonyl) super acid labile amino polyethyleneglycol resin.
H2N-tagged HMB-PEG-resin
TentaGel resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which poly(ethylene glycol) (PEG or POE) is grafted. Synonyms: NH2-(HMB)-PEG Resin; TentaGel B HMB/NH2; H2N-tagged Hydroxymethylbenzyl polyethyleneglycol resin.
H2PC
H2PC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Phthalocyanine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 574-93-6. Molecular formula: C32H18N8. Mole weight: 514.54 g/mol. Product ID: ACM574936. Alfa Chemistry ISO 9001:2015 Certified.
H2S Donor 5a
Cysteine-activated hydrogen sulfide (H2S) donor. Regulates the rate of H2S generation. Group: Biochemicals. Grades: Highly Purified. CAS No. 134861-13-5. Pack Sizes: 5mg, 25mg. Molecular Formula: C14H11NO2S. US Biological Life Sciences.
Worldwide
H3B-120
H3B-120 is a competitive and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with antitumor activity. A carbamoyl phosphate assay revealed that H3B-120 inhibited carbamoyl phosphate synthetase activity of CPS1 with IC50 of ~1.5 mM. Synonyms: N1-Benzyl-N1-methyl-N4-(4-methylthiazol-2-yl)piperidine-1,4-dicarboxamide. CAS No. 2194903-42-7. Molecular formula: C19H24N4O2S. Mole weight: 372.48.
H3B-5942
H3B-5942 is a selective, irreversible and covalent antagonist of estrogen receptor, which inactivates both ERα WT and ERα mutation. CAS No. 2052128-15-9. Molecular formula: C31H34N4O2. Mole weight: 494.63.
H3B-6527
H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC 50 of <1.2 nM. H3B-6527 has at least 250-fold selectivity over FGFR1-3 with IC 50 s of 320 nM, 1290 nM and 1060 nM respectively. H3B-6527 has potent anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1702259-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100491.
H3B-6527
H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity. Synonyms: N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527. CAS No. 1702259-66-2. Molecular formula: C29H34Cl2N8O4. Mole weight: 629.543.
H3B-6545
H3B-6545, an orally bioavailable, potent and selective estrogen receptor covalent antagonist (SERCA), is used in the study of metastatic ER-positive and HER2-negative breast cancer. Synonyms: 2-Butenamide, N,N-dimethyl-4-[[2-[[5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl]oxy]ethyl]amino]-, (2E)-; (2E)-N,N-Dimethyl-4-{[2-({5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl}oxy)ethyl]amino}-2-butenamide. Grade: ≥95%. CAS No. 2052130-80-8. Molecular formula: C30H29F4N5O2. Mole weight: 567.58.
H3B-6545
H3B-6545 is an oral, selective estrogen receptor covalent antagonist ( SERCA ) for the research of metastatic ER-positive, HER2-negative breast cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2052130-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112596.
H3B-6545 hydrochloride
H3B-6545 hydrochloride is an oral, selective estrogen receptor covalent antagonist ( SERCA ) for the research of metastatic ER-positive, HER2-negative breast cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2052132-51-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112596A.
H3B-6545 hydrochloride
H3B-6545 hydrochloride, an orally bioavailable, potent and selective estrogen receptor covalent antagonist (SERCA), is used in the study of metastatic ER-positive and HER2-negative breast cancer. Synonyms: (2E)-N,N-Dimethyl-4-{[2-({5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl}oxy)ethyl]amino}-2-butenamide hydrochloride (1:1); 2-Butenamide, N,N-dimethyl-4-[[2-[[5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl]oxy]ethyl]amino]-, (2E)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 2052132-51-9. Molecular formula: C30H30ClF4N5O2. Mole weight: 604.04.
H3B-8800
H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1825302-42-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111517.
H3 receptor-MO-1
H3 receptor-MO-1 is a histamine H3 receptor modulator. Synonyms: Benzamide, 4-[(1S,2S)-2-[[(2R)-4-cyclobutyl-2-methyl-1-piperazinyl]carbonyl]cyclopropyl]-; 4-[(1S,2S)-2-{[(2R)-4-Cyclobutyl-2-methyl-1-piperazinyl]carbonyl}cyclopropyl]benzamide. Grade: ≥95%. CAS No. 1240914-03-7. Molecular formula: C20H27N3O2. Mole weight: 341.45.
H3R-IN-1 Hydrochloride
H3R-IN-1 Hydrochloride is a histamine receptor 3 (H3R) inverse agonist. (Extracted from patent WO2013107336A1, compound example 2). Synonyms: 4-{[3-(1,3-Benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]methyl}-1-cyclobutylpiperidine hydrochloride (1:1); Piperidine, 4-[[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]methyl]-1-cyclobutyl-, hydrochloride (1:1). Grade: ≥95%. Molecular formula: C19H24ClN3O3. Mole weight: 377.87.
H-4-(2-(Boc-amino)ethoxy)-Phe-Ome
H-4-(2-(Boc-amino)ethoxy)-Phe-OMe is a protected amino acid derivative used in peptide synthesis. The Boc (tert-butoxycarbonyl) group protects the amino group during synthesis, preventing side reactions. The OMe indicates a methyl ester at the carboxyl terminus, which can be used as a protective group or for coupling reactions. This compound is useful for introducing specific structural modifications into peptides, impacting their function or stability. Synonyms: H-Tyr(2-Boc-ea)-OMe; L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, methyl ester. Grade: ≥95%. CAS No. 897962-34-4. Molecular formula: C17H26N2O5. Mole weight: 338.40.
H-4-(7-Hydroxycoumarin-4-yl)-Abu-OH
H-4-(7-Hydroxycoumarin-4-yl)-Abu-OH has been incorporated into proteins as a fluorescent tag. Synonyms: H-(7-Hydroxycoumarin-4-yl)-ethyl-Gly-OH; (S)-2-Amino-4-(7-hydroxy-2-oxo-2H-chromen-4-yl)butanoic acid; L-(7-hydroxycoumarin-4-yl) ethylglycine; umbelliferylethylglycine; (2S)-2-amino-4-(7-hydroxy-2-oxo-2H-1-benzopyran-4-yl)butanoic acid; H-(Umbellifer-4-yl)-ethyl-Gly-OH; 2H-1-Benzopyran-4-butanoic acid, α-amino-7-hydroxy-2-oxo-, (αS)-. Grade: ≥95%. CAS No. 905442-42-4. Molecular formula: C13H13NO5. Mole weight: 263.25.
H4R antagonist 1
H4R antagonist 1, a potent and highly selective antagonist of histamine H4 receptor (H4R) with an IC50 of 27 nM, has no significant binding affinity for other histamine receptor subtypes H1R, H2R, and H3R. Synonyms: 1-(8-bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methylazetidin-3-amine; 1-(8-Bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methyl-3-azetidinamine; 3-Azetidinamine, 1-(8-bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methyl-. Grade: ≥95%. CAS No. 1429375-54-1. Molecular formula: C11H11BrN8. Mole weight: 335.16.
H4 Receptor antagonist 1
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC 50 of 19 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 848217-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114025.
H4 Receptor antagonist 1
H4 Receptor antagonist 1 is a potent and selective inverse agonist of histamine H4 receptor, with an IC50 of 19 nM. Synonyms: Benzofuro[3,2-d]pyrimidine, 8-chloro-2-methyl-4-(4-methyl-1-piperazinyl)-; 8-Chloro-2-methyl-4-(4-methyl-1-piperazinyl)[1]benzofuro[3,2-d]pyrimidine. Grade: ≥95%. CAS No. 848217-00-5. Molecular formula: C16H17ClN4O. Mole weight: 316.79.
H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively). H-7 inhibits cell invasion and metastasis in B16BL6 cancer cells through the PKC/MEK/ERK pathway. It was also shown to inhibit Topo I and II in murine L929 cells and induce apoptosis via PKC inhibition. Synonyms: H7 dihydrochloride; H7 HCl. (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 108930-17-2. Molecular formula: C14H17N3O2S.2HCl. Mole weight: 364.29.
H-7 dihydrochloride
H-7 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 108930-17-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM. Synonyms: Protein kinase inhibitor H-89; H89; H 89. Grade: >98%. CAS No. 127243-85-0. Molecular formula: C20H20BrN3O2S. Mole weight: 446.36.
H-89
H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 127243-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15979.