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| Product | Description | |
|---|---|---|
| I-138 | I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2098211-50-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153365. |  |
| I-152 | I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 311343-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153340. | |
| I-191 | I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1690172-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117793. | |
| I-191 | I-191 is a potent antagonist of protease activated receptor 2 (PAR2). Synonyms: 4-[8-Tert-Butyl-6-(4-Fluorophenyl)Imidazo[1,2-B]Pyridazine-2-Carbonyl]-3,3-Dimethylpiperazin-2-One; PAR2 Antagonist I-191; SCHEMBL16598387; GTPL10268; BCP32684. Grades: 98%. CAS No. 1690172-25-8. Molecular formula: C23H26FN5O2. Mole weight: 423.5. |  |
| I2906 | Under in vitro conditions, I2906 showed excellent antimycobacterial activities and low cytotoxicity. In a murine model infected with M. tuberculosis H37Rv, the reductions on bacterial loads of both lungs and spleen were statistically significant (p < 0.05) between I2906-treated mice and untreated controls after 4 weeks. Further, the colony-forming unit counts in the lungs were dramatically lower (p < 0.05) than that of isoniazid-treated mice by the addition of I2906 after 8 weeks. Moreover, survival rate was increased by I2906 treatment. For multidrug-resistant strain infection, bacterial counts were reduced significantly in the lungs and spleen due to I2906 treatment in comparison with data from untreated controls (p < 0.05). Synonyms: I 2906; I-2906. Grades:>98%. CAS No. 331963-29-2. Molecular formula: C25H37N3O4. Mole weight: 443.58. | |
| i3-Bromo-4-nitropyridine | i3-Bromo-4-nitropyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 89364-04-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H3BrN2O2. US Biological Life Sciences. |  Worldwide |
| I942 | I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 868145-09-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129738. | |
| IAANS | IAANS, is a novel sulfhydryl-reactive probe that cna be used as a Fluorescence dye. Group: Biochemicals. Grades: Highly Purified. CAS No. 143756-46-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H14IN2NaO4S, Molecular Weight: 504.27. US Biological Life Sciences. | Worldwide |
| IACS-010759 | IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Synonyms: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. Grades: ≥98%. CAS No. 1570496-34-2. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57. | |
| IACS-010759 | IACS-010759 Inhibitor. Uses: Scientific use. Product Category: T5337. CAS No. 1570496-34-2. |  |
| IACS-010759 | IACS-010759 is an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 has the potential for relapsed/refractory AML and solid tumors research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IACS-10759. CAS No. 1570496-34-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037. | |
| IACS-010759 hydrochloride | IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IACS-10759 hydrochloride. CAS No. 1807523-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037A. | |
| IACS-8779 | IACS-8779 is a highly potent agonist of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. IACS-8779 shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma when compared to one of the clinical benchmark compounds. Synonyms: SCHEMBL23046679; 2243079-26-5; AKOS040733407. Grades: >98%. CAS No. 2243079-26-5. Molecular formula: C21H25N9O10P2S2. Mole weight: 689.56. | |
| IACS-8803 | IACS-8803 is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. Compared to one of the clinical benchmark compounds, it shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma. Synonyms: CHEMBL4596454; SCHEMBL22930678; SCHEMBL23710564; 2095690-70-1; AKOS040733408. Grades: >98%. CAS No. 2095690-70-1. Molecular formula: C20H23FN10O9P2S2. Mole weight: 692.53. | |
| IACS-9571 | IACS-9571, a benzoimidazol derivative, has been found to be a TRIM24 and BRPF1 inhibitor and could be probably significant in anticancer studies. Synonyms: N-(6-(3-(4-(dimethylamino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamide; IACS-9571; IACS 9571; IACS9571; IACS 009571-001-4. Grades: 98%. CAS No. 1800477-30-8. Molecular formula: C32H42N4O8S. Mole weight: 642.77. | |
| IACS-9571 hydrochloride | IACS-9571 (ASIS-P040) hydrochloride is a potent and selective inhibitor of TRIM24 and BRPF1 , with an IC 50 of 8 nM for TRIM24, and K d s of 31 nM and 14 nM for TRIM24 and BRPF1, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASIS-P040 hydrochloride. CAS No. 2319611-93-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102000B. | |
| Iadademstat | Iadademstat (ORY-1001) is a highly potent, orally active and selective LSD1 (KDM1A) inhibitor with antileukemic activity. Iadademstat can be used for relapsed or refractory acute myeloid leukemia research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORY-1001. CAS No. 1431304-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109117. | |
| Iadademstat dihydrochloride | Iadademstat (ORY-1001) dihydrochloride is a selective irreversible lysine (K)-specific demethylase 1A ( KDM1A / LSD1 ) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride. CAS No. 1431303-72-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12782T. | |
| IAG933 | IAG933 (YAP-TEAD-IN-3) is an orally available YAP/TAZ-TEAD inhibitor that has anti-tumor effects and promotes apoptosis. IAG933 YAP-TEAD-IN-3 inhibits Avi-human TEAD 4217-434 , with an IC 50 value of 9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YAP-TEAD-IN-3. CAS No. 2714434-21-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-153811. | |
| Iα52 acetate | Iα52 acetate is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Synonyms: Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C75H122N20O27. Mole weight: 1735.89. | |
| IALYLQQNW | IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW is able to activate EBV-specific cytotoxic T lymphocytes (CTLs), which are able to recognize and kill EBV-infected cells expressing LMP1. IALYLQQNW plays an important role in the immune response against EBV-associated tumors and can be used in the study of Hodgkin's disease and nasopharyngeal carcinoma [1]. Uses: Scientific research. Group: Peptides. CAS No. 610268-80-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10607. | |
| Ianalumab | Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VAY-736. CAS No. 1929549-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99653. | |
| IASOtoc | | |
| IAXO-102 | IAXO-102 is a TLR4 antagonist that modulates non-hematopoietic TLR4 proinflammatory signalling and inhibits experimental abdominal aortic aneurysm (AAA) development. Synonyms: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; EX-A3691; AKOS037648519; BS-14387; HY-125171; CS-0089755; D70080; Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-|A-D-glucopyranoside. CAS No. 1115270-63-7. Molecular formula: C35H71NO5. Mole weight: 585.94. | |
| IB-00208 | IB-00208, a new cytotoxic polycyclic xanthone produced by Actinomadura sp. It also has anti-Gram-positive bacteria activity (MIC=0.09-1.4 nmol/L). Molecular formula: C36H34O12. Mole weight: 658.65. | |
| Ibacitabine | Ibacitabine, an antiviral compound, can be used for gene sequencing [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 5-Iodo-2'-deoxycytidine. CAS No. 611-53-0. Pack Sizes: 5 g; 10 g. Product ID: HY-W011138. | |
| Ibadronic Acid-d3 | Heterocyclic Organic Compound. Alternative Names: [1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphnic Acid; P,P'-[1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphonic Acid; Ibandronate-d3. CAS No. 1130899-41-0. Molecular formula: C9H20D3NO7P2. Mole weight: 322.25. Appearance: White Solid. Catalog: ACM1130899410. |  |
| Ibalizumab | Ibalizumab (TMB-355) is a humanised IgG4 monoclonal antibody that prevents HIV cell entry by binding to CD4 receptor. Ibalizumab has the potential for HIV-1 infection research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TMB-355; TNX-355. CAS No. 680188-33-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99028. | |
| Ibalizumab | Ibalizumab is a humanized anti-CD4 monoclonal antibody approved for the treatment of HIV-1 infection. Ibalizumab blocks HIV-1 entry into CD4 cells while preserving normal immune function. Synonyms: TMB-355; TNX-355; Trogarzo. CAS No. 680188-33-4. | |
| Ib-AMP1 | Ib-AMP1 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria and fungi. Synonyms: IBAMP1; Basic peptide AMP1; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Val-Arg-Trp-Cys. | |
| Ib-AMP2 | Ib-AMP2 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Synonyms: IBAMP2; Basic peptide AMP2; Gln-Tyr-Gly-Arg-Arg-Cys-Cys-Asn-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Lys-Arg-Trp-Cys. | |
| Ib-AMP3 | Ib-AMP3 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Synonyms: IBAMP3; Basic peptide AMP3; Gln-Tyr-Arg-His-Arg-Cys-Cys-Ala-Trp-Gly-Pro-Gly-Arg-Lys-Tyr-Cys-Lys-Arg-Trp-Cys. | |
| Ib-AMP4 | Ib-AMP4 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: IBAMP4; Basic peptide AMP4; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Arg-Arg-Trp-Cys. | |
| Ibandronate | Ibandronate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 138844-81-2. Molecular Formula: C9H24NNaO7P2. Mole Weight: 343.23. Catalog: APB138844812. |  |
| Ibandronate Impurity 10 | Ibandronate Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 905808-25-5. Molecular Formula: C8H21NO7P2. Mole Weight: 305.2. Catalog: APB905808255. | |
| Ibandronate Impurity 13 | Ibandronate Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 40870-84-6. Molecular Formula: C9H19NO2. Mole Weight: 173.26. Catalog: APB40870846. | |
| Ibandronate Impurity 2 | Ibandronate Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2377035-78-2. Molecular Formula: C8H18ClNO2. Mole Weight: 195.69. Catalog: APB2377035782. | |
| Ibandronate Impurity 5 | Ibandronate Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 26153-88-8. Molecular Formula: C7H17N. Mole Weight: 115.22. Catalog: APB26153888. | |
| Ibandronate Impurity 8 | Ibandronate Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 99282-17-4. Molecular Formula: C5H11FO7P2. Mole Weight: 264.08. Catalog: APB99282174. | |
| Ibandronate Impurity 9 | Ibandronate Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1859096-06-2. Molecular Formula: C1613C5H27N7O14P2. Mole Weight: 668.39. Catalog: APB1859096062. | |
| Ibandronate Impurity A | Grades: > 95%. CAS No. 905808-25-5. Molecular formula: C8H21NO7P2. Mole weight: 305.21. | |
| Ibandronate sodium | Ibandronate sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 138844-81-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H22NNaO7P2. US Biological Life Sciences. | Worldwide |
| Ibandronate Sodium | Ibandronate sodium is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women. In May 2003, the U.S. Food and Drug Administration (FDA) approved Ibandronate as a daily treatment for post-menopausal osteoporosis. Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers. Uses: Bone density conservation agents. Synonyms: Boniva Sodium; Bondronat Sodium; Bonviva Sodium. Grades: >98%. CAS No. 138844-81-2. Molecular formula: C9H22NNaO7P2. Mole weight: 341.21. | |
| Ibandronate sodium impurity 3 | Ibandronate sodium impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 953805-81-7. Molecular Formula: C8H20NNaO7P2. Mole Weight: 327.19. Catalog: APB953805817. | |
| Ibandronate sodium monohydrate | Ibandronate sodium monohydrate. Group: Biochemicals. Alternative Names: BM-21.0955; Bondronat. Grades: Highly Purified. CAS No. 138926-19-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H24NNaO8P2. US Biological Life Sciences. | Worldwide |
| Ibandronate Sodium Monohydrate | Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner. Synonyms: BM-21.0955. Grades:>98%. CAS No. 138926-19-9. Molecular formula: C9H23NO7P2.Na.H2O. Mole weight: 360.23. | |
| Ibandronate Sodium Monohydrate | Ibandronate Sodium Monohydrate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM-210955; RPR-102289A. CAS No. 138926-19-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0515. | |
| Ibandronate sodium salt | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-5g. Molecular Weight 341.21. See USA prepack pricing. |  |
| Ibandronate sodium salt | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-1g. Molecular Weight 341.21. See USA prepack pricing. | |
| Ibandronate sodium salt monhydrate | Ibandronate sodium salt monhydrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 138926-19-9. Molecular Formula: C9H24NNaO8P2. Mole Weight: 359.23. Catalog: APB138926199. | |
| Ibandronic acid | Ibandronic acid. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; BPH 24. Grades: Highly Purified. CAS No. 114084-78-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H23NO7P2. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid | Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. Synonyms: P, P'-[1-Hydroxy-3- (methylpentylamino) propylidene]bisphosphonic Acid; [1-Hydroxy-3- (methylpentylamino) propylidene]bisphosphonic Acid; BPH 24; Ibandronate; 1-Hydroxy-3- (methylpentylamino) propylidene]diphosphonic Acid. Grades: >98%. CAS No. 114084-78-5. Molecular formula: C9H23NO7P2. Mole weight: 319.23. | |
| Ibandronic Acid-13C,d3 | 2H Labeled Compounds. CAS No. 1261734-84-2. Mole weight: 323.24. Catalog: ACM1261734842. | |
| Ibandronic Acid ({1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphnic Acid) | A biphosphonate bone resorption inhibitor. Group: Biochemicals. Alternative Names: {1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphnic Acid. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid-d3 | Labeled Ibandronic Acid. A bisphosphonate antiresorptive agent. Bone resorption inhibitor. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; BPH 24-d3; Ibandronate-d3; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] diphosphonic Acid. Grades: Highly Purified. CAS No. 1130899-41-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid Impurity HCl | Ibandronic Acid Impurity HCl is an intermediate in the preparation of Ibandronic Acid. Synonyms: 3-(N-Methyl-N-pentylamino)propionic Acid Hydrochloride; N-Methyl-N-pentyl-β-alanine Hydrochloride; Ibanic Acid Hydrochloride; Ibandronate Related Compound A. Grades: > 95%. CAS No. 625120-81-2. Molecular formula: C9H20NO2Cl. Mole weight: 209.72. | |
| Ibandronic Acid N-(2-Methylbutyl) Impurity | Grades: > 95%. Molecular formula: C9H23NO7P2. Mole weight: 319.23. | |
| IBC 293 | IBC 293, a cell-permeable niacin triazolo derivative, is a potent and highly selective agonist for human orphan G-protein-coupled receptor GPR109b/HM74 expressed in adipocytes with EC50 value of 400 nM. It is selective for GPR109B over niacin receptor GPR109A and β-adrenergic receptor. It inhibits cAMP elevation induced by isoproterenol and forskolin in freshly isolated human adipocytes and GPR109b-expressing CHO cells. It also inhibits forskolin-stimulated cAMP release in Chinese hamster ovary cells. It also inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes. It may be relevant to atherosclerosis and dyslipidemia. Synonyms: IBC 293; IBC293; IBC-293. 1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid; 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 306935-41-1. Molecular formula: C10H11N3O2. Mole weight: 205.22. | |
| IBC 293 | IBC 293. Group: Biochemicals. Grades: Purified. CAS No. 306935-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Iberdomide | Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC 50 of ~150?nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-220. CAS No. 1323403-33-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101291. | |
| Iberdomide | Iberdomide, also known as CC-220, is potentially for the treatment of systemic lupus erythematosus. Iberdomide significantly reduced Ikaros and Aiolos protein levels in B cells, T cells and monocytes. In SLE PBMC cultures, iberdomide inhibited anti-dsDNA and anti-phospholipid autoantibody production (IC50 ?10?nM). Group: Others. Alternative Names: CC-220; CC220; CC 220; Iberdomide. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. Appearance: Solid powder. Purity: >98%. IUPACName: (S)-3- (4- ( (4- (morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2, 6-dione. Canonical SMILES: O=C ([C@@H] (N (CC1=C2C=CC=C1OCC3=CC=C (CN4CCOCC4)C=C3)C2=O)CC5)NC5=O. Catalog: ACM1323403333. | |
| Iberdomide | Iberdomide (CC-220) is a cereblon modulator with an IC50 of 60 nM. It has antitumor and immunomodulatory activities. Synonyms: (3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione; CC-220; CC220; CC 220; Iberdomide. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. | |
| Iberin | Iberin. Group: Biochemicals. Alternative Names: 1-Isothiocyanato-3-(methylsulfinyl)-propane; 3-Methylsulfinylpropyl Isothiocyanate; NSC 321801. Grades: Highly Purified. CAS No. 505-44-2. Pack Sizes: 5mg. Molecular Formula: C5H9NOS2, Molecular Weight: 163.26. US Biological Life Sciences. | Worldwide |
| Iberin | Iberin, a naturally occurring member of isothiocyanate family found in cruciferous plants, inhibits cell survival (IC50 = 2.3 μM in HL60 cell). Synonyms: 1-isothiocyanato-3-methylsulfinylpropane; 1-isothiocyanato-3-(methylsulfinyl)propane; 1-isothiocyanato-3-(methylsulphinyl)propane; iberin; IMSP. CAS No. 505-44-2. Molecular formula: C5H9NOS2. Mole weight: 163.26. | |
| Iberiotoxin | Heterocyclic Organic Compound. Alternative Names: IBTX;IBTX (SCORPION, BUTHUS TAMULUS);IBERIOTOXIN;IBERIOTOXIN, BUTHUS TAMULUS;IBERIOTOXIN SCORPION BUTHUS TAMULUS;PGLU-PHE-THR-ASP-VAL-ASP-CYS-SER-VAL-SER-LYS-GLU-CYS-TRP-SER-VAL-CYS-LYS-ASP-LEU-PHE-GLY-VAL-ASP-ARG-GLY-LYS-CYS-MET-GLY-LYS-LYS-CYS-ARG-CYS-. CAS No. 129203-60-7. Molecular formula: C179H274N50O55S7. Mole weight: 4230.85. Appearance: Salt-free lyophilized solid. Purity: 99 % (HPLC). Catalog: ACM129203607. | |
| Iberiotoxin | Iberiotoxin, a toxin extracted from the venom of the scorpion Buthus tamulus, is a selective blocker of high-conductance Ca2+-activated K+ channel. Synonyms: Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH (Disulfide bridge: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35); 5-Oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-L-glutamine cyclic (7?28),(13?33),(17?35)-tris(disulfide); 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin. Grades: ≥96% by HPLC. CAS No. 129203-60-7. Molecular formula: C179H274N50O55S7. Mole weight: 4230.85. | |
| Iberiotoxin | Iberiotoxin is a toxin isolated from Buthus tamulus scorpion venom. Iberiotoxin is a selective high conductance high conductance Ca 2+ -activated K + channel inhibitor with a K d of ~1 nM. Iberiotoxin does not block other types of voltage-dependent ion channels [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 129203-60-7. Pack Sizes: 100 μg. Product ID: HY-P0190. | |
| Iberiotoxin trifluoroacetate salt | Iberiotoxin is a 37-amino acid peptide toxin purified from the scorpion Buthus tamulus. It acts as a blocker of high conductance Ca(2+)-activated K+ channels at nanomolar concentrations. Grades: ≥95%. CAS No. 182897-30-9. Mole weight: 4230.9. | |
| I-BET151 | I-BET151 (GSK1210151A) is a BET bromodomain inhibitor which inhibits BRD4 , BRD2 , and BRD3 with pIC 50 of 6.1, 6.3, and 6.6, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK1210151A. CAS No. 1300031-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13235. | |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Synonyms: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. | |
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