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Product
Ivermectin B1a-[d2] Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Synonyms: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Grade: ≥94%; ≥95% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. BOC Sciences
Ivermectin B1a-D2 Ivermectin B1a-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. Appearance: Pale Beige to Brown Solid. CAS No. 71827-03-7 (Unlabelled). Molecular formula: C48H72D2O14. Mole weight: 877.11. Purity: 0.94. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-2. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Ivermectin B1a-D2 Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences. USBiological 5
Worldwide
Ivermectin B1 Aglycon Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences. USBiological 3
Worldwide
Ivermectin B1 Aglycon Ivermectin B1 Aglycon. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-, (6R,13S,25R)-,(6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B, 22,23-Dihydroavermectin B1a Aglycon, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B Deriv., Ivermectin Imp. G (EP), Ivermectin Aglycone, [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. CAS No. 73162-95-5. Pack Sizes: 1MG. Molecular formula: C34H50O8. Mole weight: 586.76. Catalog: APS73162955. SMILES: CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(/C)\[C@@H](O)[C@@H](C)\C=C\C=C\4/CO[C@@H]5[C@H](O)C(=C[C@@H](C(=O)O3)[C@]45O)C)O2. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
Ivermectin B1 aglycone A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grade: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76. BOC Sciences
Ivermectin B1b Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Ivermectin B1b; Avermectin H2B1b; Ivermectin Component B1b; dihydroavermectin B1b; 70209-81-3; 22,23-dihydroavermectin B1b; 0W28CYI3TU; CHEBI:63943; Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-; (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one; UNII-0W28CYI3TU; Stromectol (TN); Soolantra (TN); EINECS 274-384-5; Sklice (TN); H2B1b; CHEMBL552; Ivermectin (JAN/USP/INN); SCHEMBL313003; DTXSID3023182; VARHUCVRRNANBD-PVVXTEPVSA-N; IVERMECTIN COMPONENT B1B [MI]; HY-125729; CS-0093431; NS00093438; D00804; Q27132925; 5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A; Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. Grade: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C20H38N6O4. Mole weight: 426.6. BOC Sciences
Ivermectin B1b Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences. USBiological 1
Worldwide
Ivermectin B1 monosaccharide Ivermectin B1 monosaccharide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. Appearance: White to off-white solid. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Purity: 0.98. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Product ID: ACM71837279. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Ivermectin B1a monosaccharide. Alfa Chemistry.
Ivermectin B1 Monosaccharide Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences. USBiological 2
Worldwide
Ivermectin-d2 Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
Ivermectin-d2 An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grade: > 95%. Molecular formula: C48H72O14D2. Mole weight: 877.13. BOC Sciences
Ivermectin-[d2] Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2/Covid-19. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Grade: 98% by CP; 97% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. BOC Sciences
Ivermectin-D2 Ivermectin-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22,23-Dihydroavermectin B1-d2. Appearance: White to Pale Beige Solid. CAS No. 70288-86-7. Molecular formula: C48H72D2O14. Mole weight: 877.12. Purity: 0.97. IUPACName: (1R,4R,5'S,6R,6'S,8S,10Z,12S,13S,14Z,20R,21S,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2S,4S,5R,6S)-5-[(2R,4S,5R,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@H]1[C@H](CC[C@@]2(O1)C[C@H]3C[C@@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@@H]5O)C)C(=O)O3)O)C)O[C@@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@@H]7C[C@@H]([C@@H]([C@@H](O7)C)O)OC)OC)/C)C. Product ID: ACM70288867. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Ivermectin during the COVID-19 pandemic. Alfa Chemistry.
Ivermectin (Dihydroavermectin B1a, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a ) Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Ivermectin EP Impurity D Ivermectin EP Impurity D is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O-demethyl-28-oxo-22,23-dihydroavermectin A1a; 28-oxoH2B1a; 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10. BOC Sciences
Ivermectin EP Impurity E Ivermectin EP Impurity E is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-12-ethyl-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1a. Molecular formula: C49H76O14. Mole weight: 889.13. BOC Sciences
Ivermectin EP Impurity F Ivermectin EP Impurity F is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-25-de(1-methylpropyl)-12-ethyl-25-(1-methylethyl)-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1b. Molecular formula: C48H74O14. Mole weight: 875.11. BOC Sciences
Ivermectin EP Impurity G Ivermectin EP Impurity G is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; H2B1a aglycone. Grade: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77. BOC Sciences
Ivermectin EP Impurity H Ivermectin EP Impurity H is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: >95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. BOC Sciences
Ivermectin EP Impurity J Ivermectin EP Impurity J is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-3,4,22,23-tetrahydroavermectin A1a; Δ2,3H2B1b. Molecular formula: C47H72O14. Mole weight: 861.08. BOC Sciences
Ivermectin EP Impurity K Ivermectin EP Impurity K is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13. BOC Sciences
Ivermectin impurity 10 Ivermectin impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1135339-49-9. Molecular formula: C48H74O14. Mole weight: 875.11. Catalog: APB1135339499. Alfa Chemistry Analytical Products 4
Ivermectin impurity 5 Ivermectin impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.09. Catalog: APB102190556. Alfa Chemistry Analytical Products 4
Ivermectin monosaccharide A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grade: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92. BOC Sciences
Ivermectin Monosccharide (Dihydroavermectin B1 Monosaccharide, Ivermectin B1 Monosaccharide) Ivermectin monosaccharide is a semi-synthetic produced by the selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 monosaccharide, Ivermectin B1 monosaccharide. Grades: Highly Purified. CAS No. 123997-64-8. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) is a degradation impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: (2R,2a'Z,4'E,5S,6R,6'S,7'S,8'E,11'R, 15'S, 17a'R,20'R,20a'S)-6-((S)-sec-butyl)-20'-hydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-17'-oxo-2a1',3,4,5,6,6',10',11',14',15',17',17a',20',20a'-tetra decahydro-2'H,7'H-spir[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-2'-carbaldehyde. BOC Sciences
Ivermectin USP Ivermectin USP. Pharma Resources International LLC
CA, FL & NJ
Ivonescimab Ivonescimab (AK112) is a PD-1 / VEGF Bispecific Antibody. Ivonescimab can be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK112. CAS No. 2428381-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99675. MedChemExpress MCE
Ivosidenib Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme , it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-120. CAS No. 1448347-49-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18767. MedChemExpress MCE
Ivospemin Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBP-101. CAS No. 748119-79-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132822. MedChemExpress MCE
IVQRFKDFRNLVRLIK IVQRFKDFRNLVRLIK. Synonyms: Ile-Val-Gln-Arg-Phe-Lys-Asp-Phe-Arg-Asn-Leu-Val-Arg-Leu-Ile-Lys. Molecular formula: C95H161N29O21. Mole weight: 2045.52. BOC Sciences 10
Ivuxolimab Ivuxolimab is a fully human IgG2 agonist targeting OX40 (CD134), which selectively binds to the OX40 receptor on the surface of activated CD4+ and CD8+ T cells without inducing antibody-dependent cytotoxicity. Ivuxolimab can promote T cell proliferation, survival and cytokine (such as IFN-?, IL-2) secretion, inhibit regulatory T cell function, and enhance anti-tumor immune response. Ivuxolimab can be used in the study of melanoma, hepatocellular carcinoma, head and neck squamous cell carcinoma, etc[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2128729-41-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99159. MedChemExpress MCE
Ivy Base Ivy Base. CAS No. MIXTURE. VIGON Item # 504914. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. Vigon
America & Internationally
Ivy Extract Ivy extract is prepared from leaf and stem of araliaceae family plant Hedera nepalensis var. sinensis (tobl.) rehd. Ivy extract is a product that widely used in medicine and cosmetics. Ivy extract has the function of moisturizing skin, and reducing wrinkles on face. Group: Others. Mole weight: 472.7. Ivy Extract; Hedera Nepalensis Var. Sinensis (Tobl.) Rehd. Cat No: EXTC-059. Creative Enzymes
Ivy P.E. 4:1 (Hedera helix) Ivy P.E. 4:1 (Hedera helix). Pharma Resources International LLC
CA, FL & NJ
IWP12 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
IWP 12 IWP 12. Group: Biochemicals. Grades: Purified. CAS No. 688353-45-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
IWP 2 IWP 2. Group: Biochemicals. Grades: Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
IWP-2 IWP-2. Group: Biochemicals. Alternative Names: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide. Grades: Highly Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H18N4O2S3. US Biological Life Sciences. USBiological 7
Worldwide
IWP-2 IWP-2 is an inhibitor of Wnt processing and secretion with an IC 50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC 50 of 40 nM for the gatekeeper mutant M82F CK1δ [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 686770-61-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13912. MedChemExpress MCE
IWP-2 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
IWP-2 (N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide) Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50 = 27nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. USBiological 4
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IWP-3 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
IWP-3 (Inhibitor of Wnt Production-3) IWP-3 (Inhibitor of Wnt Production-3). Group: Biochemicals. Alternative Names: 2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N- (6-methyl-2-benzothiazolyl)-acetamide. Grades: Highly Purified. CAS No. 687561-60-0. Pack Sizes: 10mg. Molecular Formula: C22 H17 FN 4O2S3 , Molecular Weight: 484.6. US Biological Life Sciences. USBiological 9
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IWP 4 IWP 4. Group: Biochemicals. Grades: Purified. CAS No. 686772-17-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
IWP-4 IWP-4 is a small molecule Wnt inhibitor with an IC 50 of 25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 686772-17-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12879. MedChemExpress MCE
IWP-4 ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
IWP L6 IWP L6. Group: Biochemicals. Grades: Purified. CAS No. 1427782-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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IWP L6 IWP L6 (Porcn Inhibitor III) is a Porcn inhibitor with an EC 50 of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Porcn Inhibitor III. CAS No. 1427782-89-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15825. MedChemExpress MCE
IWP-O1 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
IWR-1 IWR-1. CAS No: 430429-02-0 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
IWR-1 IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway. Uses: Scientific research. Group: Signaling pathways. Alternative Names: endo-IWR 1; IWR-1-endo. CAS No. 1127442-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12238. MedChemExpress MCE
IWR-1 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
IWR-1 (IWR-1-endo) Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3 β. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3 β. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay). Group: Biochemicals. Alternative Names: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-82-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 409.4. US Biological Life Sciences. USBiological 3
Worldwide
IXA4 IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1185329-96-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139214. MedChemExpress MCE
IXA4 IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 transiently activates protective IRE1/XBP1s signaling in liver without inducing RIDD or TRAF2/JNK signaling. IXA4 treatment improves systemic glucose metabolism and liver insulin action through IRE1-dependent remodeling of the hepatic transcriptome that reduces glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Our findings indicate that systemic, transient activation of IRE1/XBP1s signaling engenders multi-tissue benefits that integrate to mitigate obesity-driven metabolic dysfunction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXA4; IXA-4; IXA 4. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1185329-96-7. Molecular formula: C24H28N4O4. Mole weight: 436.51. Purity: >98%. IUPACName: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide. Canonical SMILES: CC1=CC=C(OCCN(C(CN2N=CC(NC(=O)CCOC3=CC=CC=C3)=C2)=O)C)C=C1. Product ID: ACM1185329967. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Ixazomib. Alfa Chemistry.
IXA6 IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021106-40-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139212. MedChemExpress MCE
Ixabepilone Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXABEPILONE;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,9,9-pentamethyl-14-[(E) -1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1.0]heptadecane-8,12-dione;Aza-epothilone B;Bms 247550-1;Ixempra;Ixempra kit;Unii-K27005np0a;Azi-epothilone B. Product Category: Inhibitors. Appearance: Solid. CAS No. 219989-84-1. Molecular formula: C27H42N2O5S. Mole weight: 506.7. Purity: 0.9984. Canonical SMILES: O=C([C@@H]([C@H]([C@H](CCC[C@]1(O[C@]1(C[C@H](N2)/C(C)=C/C3=CSC(C)=N3)[H])C)C)O)C)C(C)([C@H](CC2=O)O)C. Product ID: ACM219989841. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Ixabepilone Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-247550; Aza-epothilone B. CAS No. 219989-84-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10222. MedChemExpress MCE
Ixazomib Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC 50 of 3.4 nM ( K i of 0.93 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN2238. CAS No. 1072833-77-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10453. MedChemExpress MCE
Ixazomib citrate Ixazomib citrate (MLN9708) is a selective, orally active, second-generation proteasome inhibitor. Ixazomib citrate can be used for the study of a broad range of human malignancies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN9708. CAS No. 1239908-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10452. MedChemExpress MCE
Ixazomib Citrate Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Alternative Names: NINLARO. Ixazomib citrate (Ester). Ixazomib citrate [USAN]. CAS No. 1239908-20-3. Product ID: API1239908203. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.1. EINECS: 813-102-2. SMILES: B1(OC(=O)C(O1)(CC(=O)O)CC(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl. Appearance: White to Off-white Solid. Category: Anti-Tumor APIs. Protheragen
Ixazomib Citrate The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Synonyms: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. Grade: 98%. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. BOC Sciences
Ixazomib Impurity 15 Ixazomib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10203-08-4. Molecular formula: C7H4Cl2O. Mole weight: 175.01. Catalog: APB10203084. Alfa Chemistry Analytical Products 4
Ixazomib Impurity 19 Ixazomib Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. Catalog: APB1239908203. Alfa Chemistry Analytical Products 4
Ixazomib Impurity 22 Ixazomib Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10541-71-6. Molecular formula: C7H3Cl5. Mole weight: 264.35. Catalog: APB10541716. Alfa Chemistry Analytical Products 4
Ixazomib Impurity 9 Ixazomib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.35. Catalog: APB1092351671. Alfa Chemistry Analytical Products 4
Ixekizumab Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A ( K D <3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY2439821. CAS No. 1143503-69-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9924. MedChemExpress MCE
Ixosin Ixosin is an antibacterial peptide isolated from Ixodes sinensis (Hard tick). It has activity against gram-negative bacteria and fungi. Synonyms: Gly-Leu-His-Lys-Val-Met-Arg-Glu-Val-Leu-Gly-Tyr-Glu-Arg-Asn-Ser-Tyr-Lys-Lys-Phe-Phe-Leu-Arg. Grade: 96.7%. Molecular formula: C132H208N38O32S. Mole weight: 2871.4. BOC Sciences 10

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