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| Product | Description | |
|---|---|---|
| Itraconazole-[d5] | Itraconazole-[d5] is the labelled analogue of Itraconazole. Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID-19-related research product. Synonyms: (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl-d5)-3H-1,2,4-triazol-3-one; Itrizole-d5; Oriconazole-d5; R-51211-d5; Sporamelt-d5; Sporanox-d5; Triasporin-d5. Grade: 98% by CP; 98% atom D. CAS No. 1217510-38-7. Molecular formula: C35H33D5Cl2N8O4. Mole weight: 710.66. |  |
| Itraconazole EP | (+/-)-2-sec-Butyl-4-[4-(4-{4-[(2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxy]phenyl}-piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one; Oriconazole. Grades: EP. CAS No. 84625-61-6. Product ID: 8-04363. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.64. |  |
| Itraconazole for system suitability | Itraconazole for system suitability. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Itraconazole. Product Category: Heterocyclic Organic Compound. Appearance: off-White crystalline solid. CAS No. 84625-61-5. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.633. Purity: 0.96. IUPACName: itraconazole. Density: 1.4 g/cm³. Product ID: ACM84625615. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Itraconazole Impurity 10 | Itraconazole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 154003-23-3. Molecular formula: C20H19Cl2N3O5S. Mole weight: 484.35. Catalog: APB154003233. |  |
| Itraconazole Impurity 22 | Itraconazole Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106461-41-0. Molecular formula: C22H27N5O2. Mole weight: 393.49. Catalog: APB106461410. | |
| Itraconazole Impurity 23 | Itraconazole Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103661-14-9. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.25. Catalog: APB103661149. | |
| Itraconazole (Oriconazole, Sporanox, Triasporin) | An orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Alternative Names: Oriconazole, Sporanox, Triasporin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Itraconazole solution | 2.0 mg/mL (Methanol with 1% 1M HCl), ampule of 1 mL, certified reference material. Group: Antifungals standards. | |
| Itraconazole System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| ITSA-1 | ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA)-induced cell cycle arrest, histone acetylation, and transcriptional activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 200626-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100508. |  |
| ITSA-1 (N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide, ITSA1) | Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 200626-61-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Iturin A | Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322. | |
| ITX3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ITX 3 | ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IU1 | IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817. | |
| IU1 | IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IU1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IU1-47 | IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 ?M. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 ?M. IU1-47 induces tau elimination in cultured neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 670270-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122243. | |
| IUN78876 | IUN78876, also known as 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one is a chemical reagent for research use. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IUN78876; IUN-78876; IUN 78876. Product Category: Others. Appearance: Solid powder. CAS No. 1638178-87-6. Molecular formula: C23H22F2N4O. Mole weight: 408.45. Purity: >98%. IUPACName: 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one. Canonical SMILES: O=C1N(CC2=CC=C(F)C=C2F)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4. Product ID: ACM1638178876. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ivabradine | Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155974-00-8. Pack Sizes: 1 mg. Product ID: HY-B0162. | |
| Ivabradine-[d3] | Ivabradine-[d3] is the labelled analogue of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Synonyms: Ivabradine D3; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d3 Hydrochloride; Corlentor-d3; Procoralan-d3; Ivabradine-d3. Grade: >95%. CAS No. 1217977-70-2. Molecular formula: C27H33D3N2O5. Mole weight: 471.60. | |
| Ivabradine-[d3] Hydrochloride | Ivabradine-[d3] Hydrochloride is the labelled salt of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Uses: The hydrochloride salt form of isotope labelled ivabradine. Synonyms: Ivabradine-D3 Hydrochloride; Ivabradin D3 HCl; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3 Hydrochloride; Procoralan-d3 Hydrochloride. Grade: >95%. CAS No. 1217809-61-4. Molecular formula: C27H34D3ClN2O5. Mole weight: 508.06. | |
| Ivabradine-d3 Hydrochloride | Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivabradine-[d6] hydrochloride | Ivabradine-[d6] hydrochloride is the labelled analogue of Ivabradine Hydrochloride. Ivabradine hydrochloride has been used as a potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel (HCN)2 blocker in embryoid body (EB) and rat engineered heart tissue (EHT). Synonyms: Ivabradine D6 hydrochloride; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d6 hydrochloride; Corlentor-d6; Procoralan-d6. Grade: 98% by CP. CAS No. 2070009-63-9. Molecular formula: C27H30D6N2O5.HCl. Mole weight: 511.08. | |
| Ivabradine hydrochloride | Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grade: >98%. CAS No. 148849-67-6. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. | |
| Ivabradine hydrochloride | Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148849-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0162A. | |
| Ivabradine hydrochloride | 3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride. angina therapeutic. CAS No. 148849-67-6. Product ID: 2-08361. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. | |
| Ivabradine hydrochloride | 3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride. angina therapeutic. CAS No. 148849-67-6. Product ID: 2-08377. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. | |
| Ivabradine hydrochloride | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-100mg. Molecular Weight 505.05. See USA prepack pricing. |  |
| Ivabradine hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-1g. Molecular Weight 505.05. See USA prepack pricing. | |
| Ivabradine Hydrochloride | Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ivabradine Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. | |
| Ivacaftor | N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide. CAS No. 873054-44-5. Product ID: 8-05083. Molecular formula: C24H28N2O3. Mole weight: 392.49. Properties: cystic fibrosis therapeutic, selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively. MFCD No. MFCD17171361. | |
| Ivacaftor | Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences. | Worldwide |
| Ivacaftor | Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017. | |
| Ivacaftor Carboxylic Acid | Ivacaftor Carboxylic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethyl-, 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid, 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethylbenzeneacetic acid, Ivacaftor carboxylic acid, Ivacaftor impurity 1. CAS No. 1246213-24-0. IUPAC Name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. Molecular formula: C24H26N2O5. Mole weight: 422.47. Catalog: APS1246213240. SMILES: CC(C)(C)c1cc(c(O)cc1NC(=O)C2=CNc3ccccc3C2=O)C(C)(C)C(=O)O. Format: Neat. | |
| Ivacaftor-d18 | Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences. | Worldwide |
| Ivacaftor-[d18] | Ivacaftor-[d18] is the labelled analogue of Ivacaftor. Ivacaftor is an orally bioavailable potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) that improves chloride transport. Synonyms: Ivacaftor D18. Grade: 95% by HPLC; 95% atom D. CAS No. 1413431-05-6. Molecular formula: C24H10D18N2O3. Mole weight: 410.6. | |
| Ivacaftor-d19 | Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VX-770-d19. CAS No. 1413431-22-7. Pack Sizes: 5 mg; 1 mg. Product ID: HY-13017S1. | |
| Ivacaftor impurities5 | Ivacaftor impurities5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.48. Catalog: APB1246213240. | |
| Ivacaftor impurities6 | Ivacaftor impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB1246213239. | |
| Ivacaftor impurities7 | Ivacaftor impurities7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB1246213411. | |
| Ivacaftor N-Glucuronide | Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences. | Worldwide |
| Ivarmacitinib | Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2 , 77-fold for JAK3 , 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR0302. CAS No. 1445987-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112724. | |
| Ivdde-L-Lys(Fmoc)-OH | Ivdde-L-Lys(Fmoc)-OH. Synonyms: (S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)hexanoic acid. Grade: 98%. CAS No. 1446752-60-8. Molecular formula: C34H42N2O6. Mole weight: 574.71. | |
| Ivdde-OH | Ivdde-OH. Synonyms: 2-(3-Methylbutyryl)-5,5-dimethyl-1,3-cyclohexandione. CAS No. 172611-72-2. Molecular formula: C13H20O3. Mole weight: 224.3. | |
| Ivebradine impurity 6 | Ivebradine impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1086026-31-4. Molecular formula: C27H34N2O5. Mole weight: 466.58. Catalog: APB1086026314. | |
| Ivermectin | Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X 4 and the α7 neuronal nicotinic acetylcholine receptor ( nAChRs ). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import [1] [2] [3] [4]. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MK-933; CD-5024; K-237. CAS No. 70288-86-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-15310. | |
| Ivermectin | Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grade: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16. | |
| Ivermectin | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H74O14. CAS No. 70288-86-7. Prepack ID 21022571-1g. Molecular Weight 875.09. See USA prepack pricing. | |
| Ivermectin | Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Ivermectin aglycone (Dihydroavermectin B1 aglycone, Ivermectin B1 aglycone) | Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivermectin B1a | Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. Purity: 0.85. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ivermectin B1a | Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences. | Worldwide |
| Ivermectin B1a | It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Ivermectin; Dihydroavermectin B1a; 22,23-Dihydroavermectin B1a; Ivermectin Component B1a; avermectin H2B1a; 5-O-demethyl-22,23-dihydroavermectin A1a; MK-933; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydroavermectin B(1)a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.; Ivermectin (IVM); IVM; dihydro avermectin Bla; H2B1a; Ivermectin (MK-0933). Grade: >95% by HPLC. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. | |
| Ivermectin B1a | Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) [1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71827-03-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-126937. | |
| Ivermectin B1a-[d2] | Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Synonyms: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Grade: ≥94%; ≥95% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. | |
| Ivermectin B1a-D2 | Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences. | Worldwide |
| Ivermectin B1a-D2 | Ivermectin B1a-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. Appearance: Pale Beige to Brown Solid. CAS No. 71827-03-7 (Unlabelled). Molecular formula: C48H72D2O14. Mole weight: 877.11. Purity: 0.94. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ivermectin B1 Aglycon | Ivermectin B1 Aglycon. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-, (6R,13S,25R)-,(6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B, 22,23-Dihydroavermectin B1a Aglycon, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B Deriv., Ivermectin Imp. G (EP), Ivermectin Aglycone, [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. CAS No. 73162-95-5. Pack Sizes: 1MG. Molecular formula: C34H50O8. Mole weight: 586.76. Catalog: APS73162955. SMILES: CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(/C)\[C@@H](O)[C@@H](C)\C=C\C=C\4/CO[C@@H]5[C@H](O)C(=C[C@@H](C(=O)O3)[C@]45O)C)O2. Format: Neat. Shipping: Room Temperature. | |
| Ivermectin B1 Aglycon | Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences. | Worldwide |
| Ivermectin B1 aglycone | A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grade: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76. | |
| Ivermectin B1b | Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Ivermectin B1b; Avermectin H2B1b; Ivermectin Component B1b; dihydroavermectin B1b; 70209-81-3; 22,23-dihydroavermectin B1b; 0W28CYI3TU; CHEBI:63943; Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-; (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one; UNII-0W28CYI3TU; Stromectol (TN); Soolantra (TN); EINECS 274-384-5; Sklice (TN); H2B1b; CHEMBL552; Ivermectin (JAN/USP/INN); SCHEMBL313003; DTXSID3023182; VARHUCVRRNANBD-PVVXTEPVSA-N; IVERMECTIN COMPONENT B1B [MI]; HY-125729; CS-0093431; NS00093438; D00804; Q27132925; 5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A; Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. Grade: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C20H38N6O4. Mole weight: 426.6. | |
| Ivermectin B1b | Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences. | Worldwide |
| Ivermectin B1 monosaccharide | Ivermectin B1 monosaccharide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. Appearance: White to off-white solid. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Purity: 0.98. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Product ID: ACM71837279. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin B1a monosaccharide. | |
| Ivermectin B1 Monosaccharide | Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences. | Worldwide |
| Ivermectin-d2 | An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grade: > 95%. Molecular formula: C48H72O14D2. Mole weight: 877.13. | |
| Ivermectin-d2 | Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivermectin-[d2] | Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2/Covid-19. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Grade: 98% by CP; 97% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. | |
| Ivermectin-D2 | Ivermectin-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22,23-Dihydroavermectin B1-d2. Appearance: White to Pale Beige Solid. CAS No. 70288-86-7. Molecular formula: C48H72D2O14. Mole weight: 877.12. Purity: 0.97. IUPACName: (1R,4R,5'S,6R,6'S,8S,10Z,12S,13S,14Z,20R,21S,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2S,4S,5R,6S)-5-[(2R,4S,5R,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@H]1[C@H](CC[C@@]2(O1)C[C@H]3C[C@@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@@H]5O)C)C(=O)O3)O)C)O[C@@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@@H]7C[C@@H]([C@@H]([C@@H](O7)C)O)OC)OC)/C)C. Product ID: ACM70288867. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin during the COVID-19 pandemic. | |
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