American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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isradipine Quick inquiry Where to buy Suppliers range | isradipine. Group: Heterocyclic Organic Compound. CAS No. 1901-9-12. Product ID: ACM621. | |
Isradipine Quick inquiry Where to buy Suppliers range | Isradipine. Group: Biochemicals. Grades: Purified. CAS No. 75695-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Isradipine Quick inquiry Where to buy Suppliers range | Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. Synonyms: DynaCirc; Prescal; Lomir; PN-200-110; PN-205-033; PN-205-034; 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester. Grades: >98%. CAS No. 75695-93-1. Molecular formula: C19H21N3O5. Mole weight: 371.39. | |
Isradipine (4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Methyl 1-Methylethyl Ester, Isrodipine, PN-200-110, Clivoten, DynaCirc, Esradin, Lomir, Prescal) Quick inquiry Where to buy Suppliers range | Dihydropyridine calcium channel blocker. Antihypertensive; antianginal. Group: Biochemicals. Alternative Names: 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Methyl 1-Methylethyl Ester; Isrodipine; PN-200-110; Clivoten; DynaCirc; Esradin; Lomir; Prescal. Grades: Highly Purified. CAS No. 75695-93-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Isradipine-d3 Quick inquiry Where to buy Suppliers range | Dihydropyridine calcium channel blocker. Antihypertensive; antianginal. Group: Biochemicals. Alternative Names: 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Methyl-d3 1-Methylethyl Ester; Isrodipine-3; PN-200-110-d3; Clivoten-d3; DynaCirc-d3; Esradin-d3; Lomir-d3; Prescal-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Isradipine Impurity A Quick inquiry Where to buy Suppliers range | Synonyms: 4-Benzo[1,2,5]oxadiazol-4-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester. Grades: > 95%. Molecular formula: C18H19N3O5. Mole weight: 357.37. | |
Isradipine impurity B Quick inquiry Where to buy Suppliers range | Isradipine impurity B. Uses: For analytical and research use. Group: British Pharmacopoeia; Pharmacopoeial Standards. IUPAC Name: dipropan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Molecular formula: C21H25N3O5. Mole weight: 399.44. Catalog: APS009131. SMILES: CC (C)OC (=O)C1=C (C)NC (=C (C1c2cccc3nonc23)C (=O)OC (C)C)C. Format: Neat. Product Type: Impurity. Shipping: Room Temperature. | |
Isradipine Impurity B Quick inquiry Where to buy Suppliers range | Synonyms: 4-Benzo[1,2,5]oxadiazol-4-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diisopropyl ester. Grades: > 95%. Molecular formula: C21H25N3O5. Mole weight: 399.45. | |
Isradipine Impurity C Quick inquiry Where to buy Suppliers range | Synonyms: 4-Benzo[1,2,5]oxadiazol-4-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester. Grades: > 95%. Molecular formula: C17H17N3O5. Mole weight: 343.34. | |
Isradipine impurity D Quick inquiry Where to buy Suppliers range | Isradipine impurity D. Uses: For analytical and research use. Group: British Pharmacopoeia; European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: Methyl 1-methylethyl 4-(2,1,3-benzoxadiazol-4-yl) -2,6-dimethylpyridine-3,5-dicarboxylate, Dehydro Isradipine, PN 203-831,3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-, methyl 1-methylethyl ester (9CI), Isradipine EP impurity D, 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-2,6-dimethyl-, methyl 1-methylethyl ester, Isopropyl methyl 4-(4-benzofurazanyl)-2,6-dimethyl-3,5-pyridinedicarboxylate, 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv. CAS No. 116169-18-7. IUPAC Name: 3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethylpyridine-3,5-dicarboxylate. Molecular formula: C19H19N3O5. Mole weight: 369.37. Catalog: APS116169187. SMILES: COC (=O)c1c (C)nc (C)c (C (=O)OC (C)C)c1c2cccc3nonc23. Format: Neat. Product Type: Impurity. | |
Isradipine Impurity E Quick inquiry Where to buy Suppliers range | Synonyms: 4-Benzo[1,2,5]oxadiazol-4-yl-2-(2-benzo[1,2,5]oxadiazol-4-yl-vinyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-isopropyl ester 3-methyl ester. Grades: > 95%. Molecular formula: C26H23N5O6. Mole weight: 501.50. | |
Isradipine lactone Quick inquiry Where to buy Suppliers range | Isradipine derivative. Synonyms: 4-(2,1,3-Benzoxadiazol-4-yl)-1,4,5,7-tetrahydro-2-methyl-5-oxo-Furo[3,4-b]pyridine-3-carboxylic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 1076198-34-9. Molecular formula: C18H17N3O5. Mole weight: 355.35. | |
ISRIB Quick inquiry Where to buy Suppliers range | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: 2- (4-chlorophenoxy) -N-[4-[[2- (4-chlorophenoxy) acetyl]amino]cyclohexyl]acetamide 2- (4-chlorophenoxy) -N- (4- (2- (4-chlorophenoxy) acetamido) cyclohexyl) acetamide ISRIB compound trans-ISRIB. CAS No. 1597403-47-8. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
ISRIB Quick inquiry Where to buy Suppliers range | ISRIB. Uses: Peptide Inhibitors. CAS No. 548470-11-7. Product ID: PI-015. | |
ISRIB (mix-Isomer) Quick inquiry Where to buy Suppliers range | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: Acetamide, N,?N'-1,?4-cyclohexanediylbis[2?-(4-chlorophenoxy)?- ISRIB compound. CAS No. 548470-11-7. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
ISS610 Quick inquiry Where to buy Suppliers range | ISS610 is a Signal transducer and activator of transcription 3 (STAT3) inhibitor. Reported has shown that aberrant activation of oncogenic signal transducer and activator of STAT3 protein signaling pathways is implicated in human cancers. Uses: Cancer. Synonyms: ((S)-2-(4-cyanobenzamido)-3-(4-(phosphonooxy)phenyl)propanoyl)-L-leucine. Grades: 98%. CAS No. 725233-55-6. Molecular formula: C23H26N3O8P. Mole weight: 503.45. | |
Istamycin A Quick inquiry Where to buy Suppliers range | Istamycin A is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: Sannamycin A; Antibiotic KA 7038I; L-chiro-Inositol, 4-amino-1-((aminoacetyl)methylamino)-3-O-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-1,4,5-trideoxy-6-O-methyl-. CAS No. 72503-79-8. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
Istamycin B Quick inquiry Where to buy Suppliers range | Istamycin B is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: L-chiro-Inositol, 4-amino-1-(2-amino-N-methylacetamido)-3-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-beta-D-lyxo-hexopyranosyl)-6-O-methyl-1,4,5-trideoxy-. CAS No. 72523-64-9. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
Istaroxime Quick inquiry Where to buy Suppliers range | Istaroxime, also called as PST 2744, is an inhibitor of sodium-potassium ATPase that exhibits the unique property of increasing SERCA2a activity. This has been demonstrated in sarcoplasmic reticulum vesicles from normal guinea pigs, where istaroxime incre. Synonyms: PST-2744; PST 2744; PST2744; Istaroxime; (3E,5S,8R,9S,10R,13S,14S)-3-(2-aminoethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochlorideIstaroxi. CAS No. 203737-93-3. Molecular formula: C21H32N2O3. Mole weight: 360.49. | |
Istaroxime hydrochloride Quick inquiry Where to buy Suppliers range | Istaroxime is a adenosine triphosphatase inhibitor, inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Uses: Inhibitor of na+/k+ atpase. Synonyms: PST-2744 HCl; PST 2744 HCl; PST2744 HCl(3E,5α)-3-[(2-Aminoethoxy)imino]androstane-6,17-dione hydrochloride. Grades: ≥95%. CAS No. 374559-48-5. Molecular formula: C21H33ClN2O3. Mole weight: 396.95. | |
Istradefyline Quick inquiry Where to buy Suppliers range | Istradefyline. Group: Biochemicals. Alternative Names: (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,; 8-[ (1E) -2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-purine-2, 6-dione. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H24N4O4. US Biological Life Sciences. | Worldwide |
Istradefylline Quick inquiry Where to buy Suppliers range | Istradefylline. CAS No. 155270-99-8. | |
Istradefylline Quick inquiry Where to buy Suppliers range | Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist (Ki=2.2 nM). Uses: Adenosine a2 receptor antagonists. Synonyms: KW6002; KW 6002; KW-6002; Istradefylline. 8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione. Grades: > 95%. CAS No. 155270-99-8. Molecular formula: C20H24N4O4. Mole weight: 384.43. | |
Istradefylline Quick inquiry Where to buy Suppliers range | Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinsons disease. Group: Biochemicals. Alternative Names: (E) -8-[2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-Purine-2, 6-dione; Istradefylline; KW 6002. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Istradefylline-d3,13C Quick inquiry Where to buy Suppliers range | Istradefylline-d3,13C. Group: Biochemicals. Alternative Names: (E) -8-[2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-Purine-2, 6-dione-d3, 13C; Istradefylline-d3,13C; KW 6002-d3,13C. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1913CH21D3N4O4, Molecular Weight: 388.44. US Biological Life Sciences. | Worldwide |
Istradefylline Dimer 2 Quick inquiry Where to buy Suppliers range | Istradefylline Dimer 2 is a dimer of Istradefylline, which is a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione); 1H-Purine-2,6-dione, 8,8'-[(1α,2α,3β,4β)-2,4-bis(3,4-dimethoxyphenyl)-1,3-cyclobutanediyl]bis[1,3-diethyl-3,7-dihydro-7-methyl-; Istradefylline Impurity 25. CAS No. 702697-27-6. Molecular formula: C40H48N8O8. Mole weight: 768.86. | |
Istradefylline Dimer Impurity 1 Quick inquiry Where to buy Suppliers range | Grades: > 95%. Molecular formula: C40H50N8O8. Mole weight: 770.89. | |
Istradefylline Dimer Impurity 2 Quick inquiry Where to buy Suppliers range | Grades: > 95%. Molecular formula: C40H48N8O8. Mole weight: 768.88. | |
Istradefylline Impurity 1 Quick inquiry Where to buy Suppliers range | Synonyms: 3-(3,4-Dimethoxy-phenyl)-N-(6-dimethylamino-1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-acrylamide. Grades: > 95%. Molecular formula: C21H28N4O5. Mole weight: 416.48. | |
Istradefylline Impurity 2 Quick inquiry Where to buy Suppliers range | Synonyms: 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-purine-2,6-dione. Grades: > 95%. CAS No. 606080-73-3. Molecular formula: C20H24N4O4. Mole weight: 384.44. | |
Istradefylline Impurity 3 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 3 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H23N3O5. Mole weight: 373.40. | |
Istradefylline Impurity 4 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 4 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C30H34N4O8. Mole weight: 578.61. | |
Istradefylline Impurity 5 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 5 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H22N4O6. Mole weight: 402.40. | |
Istradefylline Impurity 6 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 6 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H23N3O5. Mole weight: 373.40. | |
Istradefylline Impurity 7 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 7 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. CAS No. 1453190-01-6. Molecular formula: C20H24N4O4. Mole weight: 384.43. | |
Istradefylline Impurity 8 Quick inquiry Where to buy Suppliers range | Istradefylline Impurity 8 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: 3,4-Dimethoxycinnamamide; 14773-40-1; 3-(3,4-Dimethoxyphenyl)propenamide; (E)-3-(3,4-dimethoxyphenyl)prop-2-enamide; (2E)-3-(3,4-dimethoxyphenyl)prop-2-enamide; 130973-10-3; CINNAMAMIDE, 3,4-DIMETHOXY-; SCHEMBL8153880; SCHEMBL8153885; 3-(3,4-Dimethoxyphenyl)acrylamide; LT0108; AKOS003421127; NCGC00385957-01; (2E)-3-(3,4-dimethoxyphenyl)-2-propenamide; NCGC00385957-01_C11H13NO3_(2E)-3-(3,4-Dimethoxyphenyl)acrylamide. CAS No. 14773-40-1. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
Istradefylline Impurity A Quick inquiry Where to buy Suppliers range | Synonyms: N-(1,3-Diethyl-2,6-dioxo-hexahydro-pyrimidin-4-yl)-3-(3,4-dimethoxy-phenyl)-acrylamide. Grades: > 95%. Molecular formula: C19H23N3O5. Mole weight: 373.41. | |
Istradefylline Impurity C Quick inquiry Where to buy Suppliers range | Grades: > 95%. Molecular formula: C30H34N4O8. Mole weight: 578.63. | |
Istradefylline Impurity F Quick inquiry Where to buy Suppliers range | Synonyms: N-(1,3-Diethyl-5-nitroso-2,6-dioxo-hexahydro-pyrimidin-4-yl)-3-(3,4-dimethoxy-phenyl)-acrylamide. Grades: > 95%. Molecular formula: C19H22N4O6. Mole weight: 402.41. | |
Istradefylline M8 Quick inquiry Where to buy Suppliers range | Istradefylline M8 is one of Istradefylline metabolites, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: 8-[(E)-2-(3,4-Dimethoxyphenyl)vinyl]-3-ethyl-1-(2-hydroxyethyl)-7-methyl-3,7-dihydro-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-3-ethyl-3,7-dihydro-1-(2-hydroxyethyl)-7-methyl-; (E)-8-(3,4-dimethoxystyryl)-3-ethyl-1-(2-hydroxyethyl)-7-methyl-1H-purine-2,6(3H,7H)-dione. CAS No. 1798429-54-5. Molecular formula: C20H24N4O5. Mole weight: 400.43. | |
Istradefylline M8 Quick inquiry Where to buy Suppliers range | Istradefylline M8. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H24N4O5, Molecular Weight: 400.43. US Biological Life Sciences. | Worldwide |
Istradefylline M8-d3,13C Quick inquiry Where to buy Suppliers range | Istradefylline M8-d3,13C. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1913CH21D3N4O5, Molecular Weight: 404.44. US Biological Life Sciences. | Worldwide |
ISX 9 Quick inquiry Where to buy Suppliers range | ISX 9. Group: Biochemicals. Grades: Purified. CAS No. 832115-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
IT-143-A Quick inquiry Where to buy Suppliers range | IT-143-A is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143A. Molecular formula: C29H43NO4. Mole weight: 469.65. | |
IT-143A Quick inquiry Where to buy Suppliers range | IT-143A is a bacterial metabolite produced by the strain of Streptomyces sp. IT-143. It is active against the bacterium M. luteus (MIC = 6.25 μg/ml) and the fungi A. fumigatus and T. rubrum in vitro (MICs = 12.5-25 μg/ml). Synonyms: IT-143-A. Grades: >95% by HPLC. CAS No. 183485-32-7. Molecular formula: C29H43NO4. Mole weight: 469.65. | |
IT-143-B Quick inquiry Where to buy Suppliers range | IT-143-B is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143B. Grades: ≥95%. CAS No. 183485-34-9. Molecular formula: C28H41NO4. Mole weight: 455.63. | |
IT1t Quick inquiry Where to buy Suppliers range | IT1t is a selective CXCR4 antagonist with IC50 value of 1.1 nM in calcium mobilization assays.It may be potential useful as anti-HIV agent. Uses: Anti-hiv agent. Synonyms: N,N'-Dicyclohexylcarbamimidothioic Acid (5,6-Dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl Ester;1092776-63-0 (HCl salt). Grades: 98%. CAS No. 864677-55-4. Molecular formula: C21H34N4S2. Mole weight: 406.65. | |
IT1t dihydrochloride Quick inquiry Where to buy Suppliers range | IT1t dihydrochloride is a potent and orally CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). Synonyms: N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride; IT1t; IT1t dihydrochloride. Grades: ≥98% (HPLC). CAS No. 1092776-63-0. Molecular formula: C21H34N4S2.2HCl. Mole weight: 479.57. | |
IT1t dihydrochloride Quick inquiry Where to buy Suppliers range | IT1t dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1092776-63-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
IT-62-B Quick inquiry Where to buy Suppliers range | IT-62-B is originally isolated from Streptomyces sp. IT-62. It had moderate anti-Gram-positive bacteria activity (MIC 6.25-12.5 μg/mL), and anti-L1210, P388, adriamycin-resistant P388 and KB tumor cells activity. Molecular formula: C39H47NO15. Mole weight: 769.79. | |
IT 901 Quick inquiry Where to buy Suppliers range | IT 901, a bioactive naphthalenethiobarbiturate derivative, potently inhibits the NF-κB subunit c-Rel with IC50 value of 3 μM. It shows its anticancer properties in Hematologic Malignancies by inhibiting the oxidative stress response in lymphoma cells. It suppressed graft-versus-host disease while preserving graft-versus-lymphoma activity during allogeneic transplantation. It did not elicit increased levels of reactive oxygen species in normal leukocytes, illustrating its cancer selective properties. It is used for the treatment of human B-cell lymphoma and reveals antitumor properties in vitro and in vivo. It is also a novel therapeutic agent to ameliorate graft-versus-host disease. Synonyms: IT-901; IT 901; IT901; 5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione. Grades: ≥98% by HPLC. CAS No. 1584121-99-2. Molecular formula: C17H14N2O4S. Mole weight: 342.37. | |
Itacitinib Quick inquiry Where to buy Suppliers range | Itacitinib is a potent and selective JAK1 inhibitor developed for the treatment of Graft-versus-host disease and non-small cell lung cancer. Synonyms: INCB 039110; 2-[1-[1-[3-fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]piperidin-4-yl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile. Grades: >98%. CAS No. 1334298-90-6. Molecular formula: C26H23F4N9O. Mole weight: 553.51. | |
Itaconic acid Quick inquiry Where to buy Suppliers range | 1kg Pack Size. Group: Organics. Formula: C5H6O4. CAS No. 97-65-4. Prepack ID 10565984-1kg. Molecular Weight 130.1. See USA prepack pricing. | |
Itaconic acid Quick inquiry Where to buy Suppliers range | Itaconic acid. Group: Heterocyclic Organic Compound. Alternative Names: methylene-butanedioicaci;methylene-succinicaci;Succinic acid, methylene-;METHYLENESUCCINIC ACID;ITACONIC ACID;3-CARBOXY-3-BUTENOIC ACID;2-PROPENE-1,2-DICARBOXYLIC ACID;PROPYLENEDICARBOXYLIC ACID. CAS No. 97-65-4. Molecular formula: C5H6O4. Mole weight: 130.1. Symbol: GHS07. Boiling Point: 268°C. Melting Point: 165-168°C(lit.). Flash Point: 268°C. Density: 1.573g/mL at 25°C(lit.). Safty Description: 26-36. Hazard statements: Xi. Supplemental Hazard Statements: H315-H319-H335. | |
Itaconic acid Quick inquiry Where to buy Suppliers range | 1kg Pack Size. Group: Organics. Formula: C5H6O4. CAS No. 97-65-4. Prepack ID 10565984-1kg. Molecular Weight 130.1. See USA prepack pricing. | |
Itaconic acid Quick inquiry Where to buy Suppliers range | Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. Group: Biochemicals. Alternative Names: 2-Methylenebutanedioic Acid; Methylenesuccinic Acid; 2-Methylenebutanedioic Acid; 2-Methylenesuccinic Acid; 2-Propene-1,2-dicarboxylic Acid; 4-Hydroxy-2-methylene-4-oxobutanoic Acid; Methylenebutanedioic Acid; NSC 3357; Propylenedicarboxylic Acid. Grades: Highly Purified. CAS No. 97-65-4. Pack Sizes: 1g, 5g. Molecular Formula: C?H?O?. US Biological Life Sciences. | Worldwide |
Itaconic Acid Quick inquiry Where to buy Suppliers range | Itaconic Acid. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. | California |
Itaconic Acid Quick inquiry Where to buy Suppliers range | Itaconic Acid. CAS No. 97-65-4. Molecular formula: C5H6O4. | |
Itaconic Acid-13C5 Quick inquiry Where to buy Suppliers range | Itaconic Acid-13C5. Uses: For analytical and research use. Group: Building Blocks. Pack Sizes: 5MG. Catalog: APS009132. Format: Neat. Product Type: Stable Isotope Labelled. Shipping: Room Temperature. | |
Itaconic Acid Diethyl Ester Quick inquiry Where to buy Suppliers range | Itaconic Acid Diethyl Ester. Group: Polymers. Alternative Names: Diethyl itaconate, Ethyl itaconate, Itaconic acid diethyl ester, NSC1794, Butanedioic acid, methylene-, diethyl ester, MolPort-000-005-475, CID75481, NSC 1794, NSC67389, NSC 67389, Succinic acid, methylene-, diethyl ester, AI3-11186, I0204, Butanedioic acid, 2-methylene-, 1,4-diethyl ester, I14-7243, 2409-52-1. CAS No. 2409-52-1. IUPAC Name: diethyl 2-methylidenebutanedioate. Molecular Weight: 186.21. Molecular Formula: C9H14O4. SMILES: CCOC(=O)CC(=C)C(=O)OCC. InChIKey: ZEFVHSWKYCYFFL-UHFFFAOYSA-N. Boiling Point: 228ºC at 760mmHg. Flash Point: 108ºC. Purity: 96%. Density: 1.04g/cm³. | |
Itaconic acid mono-n-butyl ester Quick inquiry Where to buy Suppliers range | Itaconic acid mono-n-butyl ester. Group: Polymers. Alternative Names: ITACONIC ACID MONO-N-BUTYL ESTER;BETA-BUTYL ITACONATE;4-BUTYL METHYLENESUCCINATE;MONO-N-BUTYL ITACONATE;MONO-BUTYL ITACONATE;ITACONIC ACID MONO-N-BUTYL ESTER 90+%;ITACONIC ACID MONOBUTYL ESTER;2-Methylenesuccinic acid 4-butyl ester. CAS No. 6439-57-2. IUPAC Name: 4-butoxy-2-methylidene-4-oxobutanoic acid. Molecular Weight: 186.2g/mol. Molecular Formula: C9H14O4. SMILES: CCCCOC(=O)CC(=C)C(=O)O. InChI: InChI=1S/C9H14O4/c1-3-4-5-13-8(10)6-7(2)9(11)12/h2-6H2,1H3,(H,11,12). InChIKey: VVAAYFMMXYRORI-UHFFFAOYSA-N. | |
Itaconic anhydride Quick inquiry Where to buy Suppliers range | Itaconic anhydride. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methylene-2,5-furandione; Methylenesuccinic anhydride. Grades: Highly Purified. CAS No. 2170-3-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C5H4O3. US Biological Life Sciences. | Worldwide |
Itaconic anhydride Quick inquiry Where to buy Suppliers range | Itaconic anhydride. Group: Polymer/Macromolecule. Alternative Names: ITACONIC ANHYDIDE;ITACONIC ANHYDRIDE;METHYLENESUCCINIC ANHYDRIDE;3,4-DIHYDRO-3-METHYLENE-2,5-FURANDIONE;2-METHYLENESUCCINIC ANHYDRIDE;3-Methylenedihydro-2,5-furandione;dihydro-3-methylene-2,5-furandione;dihydro-3-methylene-5-furandione. CAS No. 2170-3-8. Molecular formula: C5H4O3. Mole weight: 112.08. | |
Itaconic anhydride Quick inquiry Where to buy Suppliers range | 100g Pack Size. Group: Building Blocks, Organics. Formula: C5H4O3. CAS No. 2170-3-8. Prepack ID 89996186-100g. Molecular Weight 112.08. See USA prepack pricing. | |
Itaconyl chloride Quick inquiry Where to buy Suppliers range | Itaconyl chloride. Group: Polymer/Macromolecule. Alternative Names: ITACONYL CHLORIDE;METHYLENESUCCINIC ACID CHLORIDE;PROPYLENEDICARBOXYLIC CHLORIDE; 2-methylenesuccinylchloride; Methylenesuccinyl chloride;succinylchloride, methylene;2, 2-methylenesuccinyl dichloride;ITACONYL CHLORIDE, TECH., 90%. CAS No. 1931-60-8. Molecular formula: C5H4Cl2O2. Mole weight: 166.99. | |
ITD 1 Quick inquiry Where to buy Suppliers range | ITD 1. Group: Biochemicals. Grades: Purified. CAS No. 1099644-42-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
ITD-1 Quick inquiry Where to buy Suppliers range | ITD-1 is an effective and highly selective TGF-β signaling inhibitor. It promotes differentiation of cardiomyocytes from embryonic stem cells (ESCs) via TGF-β type II receptor degradation. Uses: Itd-1 is an effective and highly selective tgf-β signaling inhibitor so that it might have potential application prospectin in immunity therapy. Synonyms: ITD 1; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate. Grades: >98%. CAS No. 1099644-42-4. Molecular formula: C27H29NO3. Mole weight: 415.52. | |
ITE Quick inquiry Where to buy Suppliers range | ITE is an Aryl hydrocarbon receptor ligand that acts as an endogenous aryl hydrocarbon receptor (AhR) agonist (Ki = 3 nM). Uses: Endogenous aryl hydrocarbon receptor (ahr) agonist. Synonyms: 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester. Grades: ≥98 %. CAS No. 448906-42-1. Molecular formula: C14H10N2O3S. Mole weight: 286.31. | |
ITH 12575 Quick inquiry Where to buy Suppliers range | ITH 12575, a potent and selective inhibitor of mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor, reduced Ca(2+) influx through CALHM1 at low micromolar concentrations. It can be used to study the physiological roles of the mitochondrial sodium /calcium exchanger related to neurodegeneration. Synonyms: ITH-12575; ITH 12575; ITH12575; 7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one; ITH-12575; ITH12575. Grades: ≥98% by HPLC. CAS No. 1802013-08-6. Molecular formula: C18H18ClNOS. Mole weight: 331.86. | |
ITI214 Quick inquiry Where to buy Suppliers range | ITI214 is a highly selective PDE1 inhibitor (Ki = 58 pM) at picomolar concentration without disrupting other PDE family members and a panel of enzymes, receptors, transporters, and ion channels. Synonyms: Lenrispodun phosphate; PDE1-IN-1 (phosphate); ITI 214; ITI-214. CAS No. 1642303-38-5. Molecular formula: C29H29FN7O5P. Mole weight: 605.56. |