A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
P005091. Group: Biochemicals. Alternative Names: 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. Molecular Formula: C12H7Cl2NO3S2, Molecular Weight: 348.22. US Biological Life Sciences.
Worldwide
P005091
P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P5091. CAS No. 882257-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15667.
Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2um). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
P1075
P1075. Group: Biochemicals. Grades: Purified. CAS No. 60559-98-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
P11
P11 is a potent antagonist of the integrin αvβ3-vitronectin interaction with IC50 value of 25.72 nM. Synonyms: H-His-Ser-Asp-Val-His-Lys-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-L-valyl-L-histidyl-L-lysinamide; HSDVHK-NH2. Grade: >98%. CAS No. 848644-86-0. Molecular formula: C30H48N12O9. Mole weight: 720.78.
P11
P11 is a selective inhibitor of platelet-activating factor acetylhydrolases ( PAFAHs ) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC 50 values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 942285-55-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-111053.
P110 heptapeptide
P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases[1][2][3]. Uses: Scientific research. Group: Peptides. CAS No. 1411976-18-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10368.
P110 TFA
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor that inhibits Drp1 GTPase activity. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2.TFA; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-glycyl-glycyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-prolyl-L-arginyl-glycyl-L-serinamide trifluoroacetic acid; Dynamic-related protein 1 (Drp-1)-specific inhibitor P110 trifluoroacetate; P 110 (peptide) trifluoroacetate; P 110 TFA; P-110 TFA. Grade: ≥95%. Molecular formula: C102H180F3N45O27. Mole weight: 2525.80.
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans [1]. Uses: Scientific research. Group: Peptides. CAS No. 190673-58-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2148.
P11 (His-Ser-Asp-Val-His-Lys-NH2, Potent antagonist of alphavbeta3-vitronectin Interaction, Antiangiogenic)
Potent antagonist of the integrin avb3-vitronectin interaction (IC50 = 25.72nm). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 848644-86-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
P-132
P-132 is an antibiotic produced by Microbispora P-132, W-17 and 37-26. It is effective against gram-positive bacteria, fungi and actinomycetes. Synonyms: P 132. Molecular formula: C14H10N2O3. Mole weight: 254.24.
p14ARF-ORF3 (125-133)
p14ARF-ORF3 (125-133).
P15
P15 is an antimicrobial peptide found in Cervus elaphus (New Zealand red deer), and has antimicrobial activity against gram-negative bacterium Escherichia coli O111 (MIC=0.3 μg/mL), gram-positive bacterium Staphylococcus aureus NCTC 4163 (MIC=1 μg/mL) and Fungi Candida albicans 3135A (MIC=3 μg/mL). Synonyms: deer beta-defensin. Grade: >98%.
P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt
P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt. Group: Biochemicals. Alternative Names: AP3A. Grades: Highly Purified. CAS No. 5959-90-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H27N10O16P3. US Biological Life Sciences.
Worldwide
p16-INK-4a human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
p16-INK-4a TAT human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
P17 Peptide
P17 Peptide is a human TGF-β1 inhibitory peptide. P17 Peptide can block woodchuck TGF-β1 activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 846546-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10634.
P-18
P-18 is an antimicrobial peptide with anti-gram-positive bacteria, gram-negative bacteria, Cancer cells and Mammalian cells activity. The source of P-18 is Sequence reverse. Synonyms: Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Pro-Lys-Phe-Leu-His-Leu-Ala-Lys-Lys-Phe; Cecropin A(1-8)-Magainin 2(1-12) hybrid peptide analogue; P18. Grade: ≥98%. Molecular formula: C118H186N28O19. Mole weight: 2300.95.
p18INK4C, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
p19INK4D, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
P1, Human
It is a cell-penetrating peptide (CPP) derived from the human immunoglobulin heavy chain sequence. At low molar concentration, it can permeate cell membrane without obvious influence on cell membrane. CPP can bind macromolecules and be used as drug delivery vectors. Synonyms: H-Met-Gly-Leu-Gly-Leu-His-Leu-Leu-Val-Leu-Ala-Ala-Ala-Leu-Gln-Gly-Ala-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val-OH; Human P1. Grade: 97%. Molecular formula: C134H229N39O31S. Mole weight: 2914.61.
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5?-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. Group: Biochemicals. Alternative Names: P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, 94108-02-8, A(5)P5(5)A, AC1O4WDE, D6392_SIGMA, CTK8G2238, EINECS 302-339-2, AP5A lithium salt P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, AG-H-86941, Diadenosine pentaphosphate trilithium salt, Diadenosine pentaphosphate pentalithium salt, K00187, A(5 inverted exclamation marka)P5(5 inverted exclamation marka)A trilithium sal. Grades: Highly Purified. CAS No. 75522-97-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H26N10O22P5Li3, Molecular Weight: 934.17. US Biological Life Sciences.
Worldwide
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC)
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Intermediate in the synthesis of Tenofovir impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1255525-18-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
P21
When administered peripherally to normal adult mice, the pentamer P21 significantly enhanced cognition, increased proliferation and neuronal differentiation of adult hippocampal progenitors and promoted the expression of synaptic vesicle proteins, synaptophysin and synapsin I. P21 induced enhancement of neurogenesis and maturation of newly born neurons in the granular cell layer and subgranular zone of the dentate gyrus. Synonyms: Ac-Asp-Gly-Gly-Leu-adamantane-Gly-NH2; N-Acetyl-L-α-aspartylglycylglycyl-N-[(1s,3S,5R,7S)-3-(aminocarbonyl)tricyclo[3.3.1.13,7]dec-1-yl]-L-leucinamide. Grade: ≥95%. Molecular formula: C27H42N6O8. Mole weight: 578.66.
p21-Activated Kinase Inhibitor II, PF-3758309 (PAK Inhibitor II, PF3758309, (S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-(2-methylthieno[3,2-d]pyrimidin-4-ylamino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide)
A cell-permeable pyrrolopyrazole that acts as a potent inhibitor against p21-activated kinases (Ki innM/[ATP] inuM = 13.7/200, 18.7/40, 18.1/80. 17.1/72, respectively, in PAK1, PAK4, PAK5, PAK6 kinase assays; IC50 = 190 and 99nM against PAK1 and PAK3, respectively) by directly targeting the kinase ATP-binding site in a reversible manner (Kd = 4.5nM using rhPAK4300-591 kinase domain). Inhibits PAK4-dependent cellular signaling (IC50 = 24.2nM against TNFalpha-stimulated NF-kappa-B activity in HEK293T) and proliferation (IC50 = 0.24 and 27nM, respectively, against HCT116 and A549 colonies formation) in vitro and the growth of human tumors in nude mice in vivo (10 to 25mg/kg; b.i.d. p.o). Group: Biochemicals. Grades: Highly Purified. CAS No. 898044-15-0. Pack Sizes: 5mg. Molecular Formula: C??H??N?OS. US Biological Life Sciences.
Worldwide
p21CIP1, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
P21 Peptide acetate
P21 Peptide has the effect of inhibiting protein transferase. Synonyms: P21 Peptide.
P 22077
P 22077. Group: Biochemicals. Grades: Purified. CAS No. 1247819-59-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
P-2281
P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P-2281 suppresses dextran sulfate sodium (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1112994-35-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-118704.
P22 N (14-30)
The peptide sequence is found in residues 14 to 30 of P22 N. P22 N is a transcriptional antiterminator that binds to N-utilization (NUT) sites on viral transcripts. P22 N modifies RNA polymerase activity by creating a termination-resistant form of the RNA polymerase complex that is able to continue transcribing the viral transcript. Synonyms: H-Asn-Ala-Lys-Thr-Arg-Arg-His-Glu-Arg-Arg-Arg-Lys-Leu-Ala-Ile-Glu-Arg-OH; P22 N-(14-30); L-asparagyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-arginyl-L-histidyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-isoleucyl-L-alpha-glutamyl-L-arginine. Grade: ≥95%. Molecular formula: C90H164N40O24. Mole weight: 2190.55.
p-(2,3-Epoxypropoxy)benzyl Alcohol
p-(2,3-Epoxypropoxy)benzyl Alcohol. Group: Biochemicals. Alternative Names: 4- (Oxiranylmethoxy) benzenemethanol; [4- (Oxiran-2-ylmethoxy) phenyl]methanol; p-(2,3-Epoxypropoxy)benzyl Alcohol; 4- (Oxiranylmethoxy) benzenemethanol; 4- (2-Oxiranylmethoxy) benzenemethanol. Grades: Highly Purified. CAS No. 4204-78-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
P-2563 III
P-2563 III is an antibiotic produced by Pseudomonas fluorescens P-2563. It is effective against gram-positive and gram-negative bacteria, especially against Pseudomonas. Molecular formula: C12H27N3O8. Mole weight: 341.36.
p-[[2,5-Dimethoxy-4-(phenylazo)phenyl]azo]phenol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 232-995-4, CID5483538, p-((2,5-Dimethoxy-4-(phenylazo)phenyl)azo)phenol, Phenol, 4-((2,5-dimethoxy-4-(phenylazo)phenyl)azo)-, Phenol, 4-(2-(2,5-dimethoxy-4-(2-phenyldiazenyl)phenyl)diazenyl)-, 10000-42-7. Product Category: Heterocyclic Organic Compound. CAS No. 10000-42-7. Molecular formula: C20H18N4O3. Mole weight: 362.381920 [g/mol]. Purity: 0.96. IUPACName: 4-[(2,5-dimethoxy-4-phenyldiazenylphenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one. Canonical SMILES: COC1=CC(=C(C=C1N=NC2=CC=CC=C2)OC)NN=C3C=CC(=O)C=C3. Density: 1.22g/cm³. ECNumber: 232-995-4. Product ID: ACM10000427. Alfa Chemistry ISO 9001:2015 Certified.
p27KIP1, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
p-(2-Bromo)vinyl Anisole
p-(2-Bromo)vinyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
p2Ca
p2Ca, a ligand containing 8 amino acids, is naturally processed and presented to the LD heterologous T-cell clone 2C. Synonyms: H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH; L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-leucine; p2Ca peptide; L-Leucine, N-(N-(N-(1-(N-(1-(N-L-leucyl-L-seryl)-L-prolyl)-L-phenylalanyl)-L-prolyl)-L-phenylalanyl)-L-alpha-aspartyl)-. Grade: ≥95%. CAS No. 142606-55-1. Molecular formula: C47H66N8O12. Mole weight: 935.07.
p-(2-Chloro)ethyl Anisole
p-(2-Chloro)ethyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
p-[(2-Chloroethyl)ethylamino]-benzaldehyde
Dark oil, 97%. CAS No. 2643-7-4. Pack Sizes: 5g, 100g. Product ID: FR-0087. Mole weight: 211.69.
Frinton Laboratories
p-[(2-Chloroethyl)ethylamino]-benzaldehyde
p-[(2-Chloroethyl)ethylamino]-benzaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: P-[(2-CHLOROETHYL)ETHYLAMINO]-BENZALDEHYDE;N-ETHYL-N-CHLOROETHYL-4-AMINO BENZALDEHYDE;TIMTEC-BB SBB007673;4-[(2-chloroethyl)ethylamino]-benzaldehyde;Benzaldehyde, 4-[(2-chloroethyl)ethylamino]-;p-(N-(2-Chloroethyl)-N-ethyl)aminobenzaldehyde;4-(N-Ethyl-N-. Product Category: Heterocyclic Organic Compound. CAS No. 2643-7-4. Molecular formula: C11H14ClNO. Mole weight: 211.69. Density: 1.153g/cm³. Product ID: ACM2643074. Alfa Chemistry ISO 9001:2015 Certified.
P2X1 Purinergic Receptor, Control Peptide
P2X1 Purinergic Receptor, Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences.
Worldwide
P2X2 Receptor Control Peptide
P2X2 Receptor Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences.
Worldwide
P2X Antagonist III (Purinergic Receptor P2X Antagonist III, N- ( (4- (4-Phenylpiperazin-1-yl) tetrahydro-2H-pyran-4-yl) methyl) -2- (phenylthio) nicotinamide)
A phenylthio-nicotinamide that acts as a high affinity P2X7 antagonist (pKi = 8.7 and 7.9, respectively, against 30nM A-804598 for rat and human P2X7 binding) and potently inhibits P2X7-dependent cellular Ca2+ mobilization (pIC50 = 8.3, 7.5, and 7.2, respectively, using 1321N1 expressing human, mouse, or rat P2X7; drug added 0.5 h prior to 3 min 0.25 mM BzATP stimulation), while exhibiting much reduced or little potency toward a panel of 50 ion channels, transporters, and receptors. Although not suitable for oral dosing due to high hepatic extraction ratios, effective delivery and brain P2X7 occupancy can be achieved via s.c. dosing in rats (30mg/kg) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
P2Y1/P2Y12 antagonist-1
P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC 50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model. Uses: Scientific research. Group: Signaling pathways. CAS No. 2738381-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149454.
A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for human P2Y1 binding), while displaying much reduced or no affinity toward other P2Y family GPCRs (Ki = ≥2.5uM toward hP2Y14; Ki >15uM toward human P2Y2, P2Y6, P2Y11, and P2Y12). Effectively inhibits 2.5uM ADP-induced platelet aggregation in vitro (IC50 = 2.1uM) and reduces FeCl2-induced carotid artery blood clot formation in anesthetized rats in vivo (10mg/kg/h i.v. infusion) with much less effect toward prolonging cuticle and mesenteric bleeding time when compared to another P2Y12 antagonist Clopidogrel. Pharmackinetic studies reveal only moderate oral bioavailability in rat. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences.
A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences.
Worldwide
p300-Ch1 (302-531) human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p300 human
recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p32 Inhibitor M36
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M36. CAS No. 802555-85-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124718.
P-3355
P-3355 is antibacterial and antifungal antibiotic produced by streptomyces amylovorus. Synonyms: Antibiotic P 3355; P 3355. CAS No. 60046-57-3. Molecular formula: C7H9NO2. Mole weight: 139.15.