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| Product | Description | |
|---|---|---|
| P005091 | P005091 is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μM). P005091 induces elevated p53 and apoptosis in cancer cell lines and displays antiangiogenic activity in vivo. The deubiquitylating enzyme USP7 (HAUSP) sits at a critical node regulating the activities of numerous proteins broadly characterized as tumor suppressors, DNA repair proteins, immune responders, viral proteins, and epigenetic modulators. Aberrant USP7 activity may promote oncogenesis and viral disease making it a compelling target for therapeutic intervention. Synonyms: P005091; P-005091; P 005091; P5091; P-5091; P 5091. Grades: 0.98. CAS No. 882257-11-6. Molecular formula: C12H7Cl2NO3S2. Mole weight: 348.212. |  |
| P005091 | P005091. Group: Biochemicals. Alternative Names: 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. Molecular Formula: C12H7Cl2NO3S2, Molecular Weight: 348.22. US Biological Life Sciences. |  Worldwide |
| P005091 (USP7 Inhibitor, 1-[5-[(2,3-Dichlorophenyl)thio]-4-n itro-2-thienyl]ethanone) | Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2um). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| P053 | P053 is an inhibitor of ceramide synthase 1 (CerS1). Synonyms: (2S)-2-amino-4-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-2-methylbutan-1-ol. Grades: ≥95%. CAS No. 2748196-63-4. Molecular formula: C18H21Cl2NO2. Mole weight: 354.27. | |
| P1 | A protein disulfide isomerase inhibitor with IC50 value of 1.7 μM. It can inhibit the proliferation of numerous cancer cell lines. Synonyms: PDI-IN-P1; PDI IN P1; PDIINP1; PDI inhibitor P1; PDI-inhibitor-P1; N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide. Grades: ≥98% by HPLC. CAS No. 1461648-55-4. Molecular formula: C30H37N3O7S. Mole weight: 583.7. | |
| P1075 | P 1075 is a Kir6 (KATP) channel opener (EC50 for relaxation of rat aorta = 7.5 nM) by causing relaxation of various isolated animal and human blood vessels. Uses: Vasodilator agents. Synonyms: P-1075; PNU-83757; U-83757; P1075; PNU83757; U83757; P 1075; PNU 83757; U 83757; N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridylguanidine. Grades: ≥99% by HPLC. CAS No. 60559-98-0. Molecular formula: C12H17N5. Mole weight: 231.3. | |
| P1075 | P1075. Group: Biochemicals. Grades: Purified. CAS No. 60559-98-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| P11 | P11 is a potent antagonist of the integrin αvβ3-vitronectin interaction with IC50 value of 25.72 nM. Synonyms: H-His-Ser-Asp-Val-His-Lys-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-L-valyl-L-histidyl-L-lysinamide; HSDVHK-NH2. Grades: >98%. CAS No. 848644-86-0. Molecular formula: C30H48N12O9. Mole weight: 720.78. | |
| P11 | P11 is a selective inhibitor of platelet-activating factor acetylhydrolases ( PAFAHs ) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC 50 values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 942285-55-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-111053. |  |
| P110 TFA | P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor that inhibits Drp1 GTPase activity. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2.TFA; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-glycyl-glycyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-prolyl-L-arginyl-glycyl-L-serinamide trifluoroacetic acid; Dynamic-related protein 1 (Drp-1)-specific inhibitor P110 trifluoroacetate; P 110 (peptide) trifluoroacetate; P 110 TFA; P-110 TFA. Grades: ≥95%. Molecular formula: C102H180F3N45O27. Mole weight: 2525.80. | |
| P- (1, 1, 2, 2, 3, 3, 4, 4, 5, 5, 6, 6, 7, 7, 8, 8, 8-heptadecafluorooctyl) phosphonic Acid 4-Methylbenzeneamine Salt | P- (1, 1, 2, 2, 3, 3, 4, 4, 5, 5, 6, 6, 7, 7, 8, 8, 8-heptadecafluorooctyl) phosphonic Acid 4-Methylbenzeneamine Salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 1263361-03-0. Pack Sizes: 25mg. Molecular Formula: C15H11F17O3NP, Molecular Weight: 607.2. US Biological Life Sciences. | Worldwide |
| P-113 | P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans [1]. Uses: Scientific research. Group: Peptides. CAS No. 190673-58-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2148. | |
| p-(1,1,3,3-Tetramethylbutyl)phenol | Purity 98%, white crystalline. Synonyms: 4-tert-Octylphenol. CAS No. 140-66-9. Pack Sizes: 10g, 50g. Product ID: FR-0872. M.P. 83-85. Mole weight: 206.33. |  Frinton Laboratories |
| P11 (His-Ser-Asp-Val-His-Lys-NH2, Potent antagonist of alphavbeta3-vitronectin Interaction, Antiangiogenic) | Potent antagonist of the integrin avb3-vitronectin interaction (IC50 = 25.72nm). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 848644-86-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| P-(1,2-Dihydroxypropyl)phosphonic Acid | Cas No. 84954-80-3. | |
| P-132 | P-132 is an antibiotic produced by Microbispora P-132, W-17 and 37-26. It is effective against gram-positive bacteria, fungi and actinomycetes. Synonyms: P 132. Molecular formula: C14H10N2O3. Mole weight: 254.24. | |
| p14ARF-ORF3 (125-133) | | |
| P15 | P15 is an antimicrobial peptide found in Cervus elaphus (New Zealand red deer), and has antimicrobial activity against gram-negative bacterium Escherichia coli O111 (MIC=0.3 μg/mL), gram-positive bacterium Staphylococcus aureus NCTC 4163 (MIC=1 μg/mL) and Fungi Candida albicans 3135A (MIC=3 μg/mL). Synonyms: deer beta-defensin. Grades: >98%. | |
| P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt | P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt. Group: Biochemicals. Alternative Names: AP3A. Grades: Highly Purified. CAS No. 5959-90-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H27N10O16P3. US Biological Life Sciences. | Worldwide |
| P17 Peptide | P17 Peptide is a human TGF-β1 inhibitory peptide. P17 Peptide can block woodchuck TGF-β1 activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 846546-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10634. | |
| P-18 | P-18 is an antimicrobial peptide with anti-gram-positive bacteria, gram-negative bacteria, Cancer cells and Mammalian cells activity. The source of P-18 is Sequence reverse. Synonyms: Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Pro-Lys-Phe-Leu-His-Leu-Ala-Lys-Lys-Phe; Cecropin A(1-8)-Magainin 2(1-12) hybrid peptide analogue; P18. Grades: ≥98%. Molecular formula: C118H186N28O19. Mole weight: 2300.95. | |
| P1 Antigen | P1 Antigen, a complex carbohydrate antigen located on red blood cells, allows for investigation of blood groupings and H antigen expression, with potential implications for transfusion reactions. Moreover, it is highly relevant in cutting-edge research pertaining to red blood cell-associated disorders, including sickle cell anemia. Synonyms: alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-GlcNAc; Galα1-4Galβ1-4-GlcNAc; alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine; alpha-D-galactopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranose; O-α-D-Galactopyranosyl-(1->4)-O-β-D-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-D-glucose; 2-Acetamido-2-deoxy-4-O-([4-O-β-D-galactopyranosyl]-β-D-galactopyranosyl)-D-glucopyranose. Grades: ≥95%. CAS No. 54832-51-8. Molecular formula: C20H35NO16. Mole weight: 545.49. | |
| P1-Antigen | P1-Antigen is a crucial biomarker in the biomedical industry used for the research of diseases such as certain types of cancers. It aids in identifying the presence of specific antigens and their related antibodies in developing targeted research strategies. Synonyms: Gal-a1,4-Gal-b1,4-GlcNAc; 2-Acetamido-2-deoxy-4-O-([4-O-b-D-galactopyranosyl]-b-D-galactopyranosyl)-D-glucopyranose. Molecular formula: C20H35NO16. Mole weight: 545.49. | |
| P1, Human | It is a cell-penetrating peptide (CPP) derived from the human immunoglobulin heavy chain sequence. At low molar concentration, it can permeate cell membrane without obvious influence on cell membrane. CPP can bind macromolecules and be used as drug delivery vectors. Synonyms: H-Met-Gly-Leu-Gly-Leu-His-Leu-Leu-Val-Leu-Ala-Ala-Ala-Leu-Gln-Gly-Ala-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val-OH; Human P1. Grades: 97%. Molecular formula: C134H229N39O31S. Mole weight: 2914.61. | |
| P1 (N-[ (1, 1-Dimethylethoxy) carbonyl]-L-phenylalanyl-O- (ethenylsulfonyl) -N-4-pentyn-1-yl-L-tyrosinamide) | Protein disulfide isomerase (PDI) inhibitor (IC50 = 1.7uM). Inhibits proliferation of numerous cancer cell lines. Cell permeable. Group: Biochemicals. Grades: Highly Purified. CAS No. 1461648-55-4. Pack Sizes: 1mg. Molecular Formula: C30H37N3O7S, Molecular Weight: 583.7. US Biological Life Sciences. | Worldwide |
| P1,P4-Di(adenosine-5') Tetraphosphate Ammonium Salt | P1,P4-Di(adenosine-5') Tetraphosphate Ammonium Salt, a derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes. Synonyms: Adenosine 5'-(Pentahydrogen Tetraphosphate) P'''?5'-Ester with Adenosine Tetraammonium Salt; Adenosine 5'-(Pentahydrogen Tetraphosphate) P'''?5'-Ester with Adenosine Ammonium Salt. Grades: 95%. CAS No. 102783-36-8. Molecular formula: C20H28N10O19P4 xNH3. Mole weight: 836.39. | |
| p1,p5-Di(adenosine-5')pentaphosphate pentalithium salt | p1,p5-Di(adenosine-5')pentaphosphate pentalithium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DIADENOSINE PENTAPHOSPHATE PENTALITHIUM SALT;DIADENOSINE PENTAPHOSPHATE LITHIUM SALT;AP5A;AP5A, LI3;AP5A, 3LI;A[5']P5[5']A PENTALITHIUM SALT;A[5']P5[5']A LITHIUM SALT;P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT. Product Category: Heterocyclic Organic Compound. Appearance: White to white with yellow cast powder. CAS No. 94108-02-8. Molecular formula: C20H29N10O22P5.5Li. Mole weight: 946.03. Purity: 0.96. IUPACName: pentalithium;bis[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate. Canonical SMILES: [Li+].[Li+].[Li+].[Li+].[Li+].C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC4C(C(C(O4)N5C=NC6=C5N=CN=C6N)O)O)O)O. ECNumber: 302-339-2. Product ID: ACM94108028. Alfa Chemistry ISO 9001:2015 Certified. |  |
| p1,p5-Di(adenosine-5')pentaphosphate,periodate oxidized sodium salt | p1,p5-Di(adenosine-5')pentaphosphate,periodate oxidized sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: P1,P5-DI[ADENOSINE 2',3'-DIALDEHYDE-5'] PENTAPHOSPHATE SODIUM SALT;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT;P1,P5-di(adenosine-5') pentaphosphate*periodate O;P1,P5-di(adenosine-2',3'-dialdehyde-5')pentaphosphate Na. Product Category: Heterocyclic Organic Compound. CAS No. 112966-12-8. Molecular formula: C20H24N10NaO21P5. Mole weight: 918.32. Purity: 0.96. Product ID: ACM112966128. Alfa Chemistry ISO 9001:2015 Certified. | |
| P1,P5-Di(adenosine-5')pentaphosphate trilithium salt | P1,P5-Di(adenosine-5')pentaphosphate trilithium salt is an indispensable biomedical compound, proficiently assuming the role of a robust purinergic receptor agonist, significantly impacting diverse cellular processes. This compound emerges as an invaluable tool in the research of neurological disorders, cancer and cardiovascular diseases. Synonyms: Ap5a. CAS No. 75522-97-3. Molecular formula: C20H26N10O22P5Li3. Mole weight: 934.17. | |
| P1,P5-Di(adenosine-5')pentaphosphate trilithium salt | A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5?-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. Group: Biochemicals. Alternative Names: P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, 94108-02-8, A(5)P5(5)A, AC1O4WDE, D6392_SIGMA, CTK8G2238, EINECS 302-339-2, AP5A lithium salt P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, AG-H-86941, Diadenosine pentaphosphate trilithium salt, Diadenosine pentaphosphate pentalithium salt, K00187, A(5 inverted exclamation marka)P5(5 inverted exclamation marka)A trilithium sal. Grades: Highly Purified. CAS No. 75522-97-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H26N10O22P5Li3, Molecular Weight: 934.17. US Biological Life Sciences. | Worldwide |
| P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC) | P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| p-(1-Piperidino)acetophenone | Crystalline. Synonyms: N-(4-Acetylphenyl)piperidine. CAS No. 10342-85-5. Pack Sizes: 5g. Product ID: FR-0935. M.P. 88-89. Mole weight: 203.29. | Frinton Laboratories |
| P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt | P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt. Group: Biochemicals. Alternative Names: Fosfomycin EP-Impurity A. Grades: Highly Purified. CAS No. 1160525-87-0. Pack Sizes: 50mg. Molecular Formula: C3H9O5P, Molecular Weight: 156.07. US Biological Life Sciences. | Worldwide |
| P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt | P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: 1160525-87-0; Diazanium; (1R,2R)-1-phosphonatopropane-1,2-diolP-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt((1R,2R)-1,2-Dihydroxypropyl)phosphonate xammonium saltstarbld0003549. CAS No. 1160525-87-0. Molecular formula: C3H9O5P.xNH3. Mole weight: 156.07 (free base). | |
| P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt | P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Phosphonic acid, P-[(1R,2R)-1,2-dihydroxypropyl]-, ammonium salt (1:?). CAS No. 1160525-87-0. IUPAC Name: azane;[(1R,2R)-1,2-dihydroxypropyl]phosphonic acid. Molecular Formula: C3H9O5P.2H3N. Mole Weight: 190.14. Catalog: APS1160525870. SMILES: N.N.C[C@@H](O)[C@H](O)P(=O)(O)O. Format: Neat. |  |
| P-[(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester | P-[(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin intermediates. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: Phosphonic acid, P-[(1R,2R)-1,2-dihydroxypropyl]-, bis(phenylmethyl) ester; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester; Dibenzyl ((1R,2R)-1,2-dihydroxypropyl)phosphonate; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic acid dibenzyl ester. Molecular formula: C17H21O5P. Mole weight: 336.32. | |
| P-[ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester | P-[ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: [ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester. Molecular formula: C24H27O7PS. Mole weight: 490.50. | |
| P-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic Acid Monoethyl Ester | Intermediate in the synthesis of Tenofovir impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1255525-18-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| P2045 | P2045 is a somatostatin analog cyclopeptide. Rhenium Re188 P2045 is the Rhenium complex of P2045. Phase I clinical trials demonstrated that Re-188 P2045 was well tolerated. Tc-99m P2045 imaging allows identification of patients who may benefit from this treatment. Although responses were not seen, survival for these heavily pretreated patients is interesting and merits further research. Synonyms: P 2045; P-2045; Cyclo(N-methyl-L-homocysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl), (11')-thioether with 3-[(2-mercaptoacetyl)amino]-L-alanyl-4-amino-L-phenylalanyl-L-cysteinyl-L-threonyl-L-serine. CAS No. 259746-53-7. Molecular formula: C68H91N15O17S2. Mole weight: 1454.68. | |
| p21-Activated Kinase Inhibitor II, PF-3758309 (PAK Inhibitor II, PF3758309, (S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-(2-methylthieno[3,2-d]pyrimidin-4-ylamino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide) | A cell-permeable pyrrolopyrazole that acts as a potent inhibitor against p21-activated kinases (Ki innM/[ATP] inuM = 13.7/200, 18.7/40, 18.1/80. 17.1/72, respectively, in PAK1, PAK4, PAK5, PAK6 kinase assays; IC50 = 190 and 99nM against PAK1 and PAK3, respectively) by directly targeting the kinase ATP-binding site in a reversible manner (Kd = 4.5nM using rhPAK4300-591 kinase domain). Inhibits PAK4-dependent cellular signaling (IC50 = 24.2nM against TNFalpha-stimulated NF-kappa-B activity in HEK293T) and proliferation (IC50 = 0.24 and 27nM, respectively, against HCT116 and A549 colonies formation) in vitro and the growth of human tumors in nude mice in vivo (10 to 25mg/kg; b.i.d. p.o). Group: Biochemicals. Grades: Highly Purified. CAS No. 898044-15-0. Pack Sizes: 5mg. Molecular Formula: C??H??N?OS. US Biological Life Sciences. | Worldwide |
| P21d hydrochloride | P21d hydrochloride is a breast tumor kinase inhibitor with IC50 value of 30 nM. It can restore E-cadherin expression and suppress migration in breast cancer cells. Synonyms: [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-4-morpholinylmethanone hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C23H22FN7O2.HCl. Mole weight: 483.93. | |
| P22077 | P22077 is a potent and selective ubiquitin-specific protease 7 (USP7) inhibitor. P22077 potently induces apoptosis in NB cells with an intact USP7-HDM2-p53 axis but not in NB cells with mutant p53 or without human homolog of MDM2 (HDM2) expression. P22077 was found to be able to sensitize chemoresistant LA-N-6 NB cells to chemotherapy. In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines. USP7-specific inhibitors like P22077 may serve not only as a stand-alone therapy but also as an effective adjunct to current chemotherapeutic regimens for treating NB with an intact USP7-HDM2-p53 axis. Synonyms: P-22077; P 22077. Grades: 0.98. CAS No. 1247819-59-5. Molecular formula: C12H7F2NO3S2. Mole weight: 315.309. | |
| P 22077 | P 22077. Group: Biochemicals. Grades: Purified. CAS No. 1247819-59-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| P-2281 | P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P-2281 suppresses dextran sulfate sodium (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1112994-35-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-118704. | |
| P22 N (14-30) | The peptide sequence is found in residues 14 to 30 of P22 N. P22 N is a transcriptional antiterminator that binds to N-utilization (NUT) sites on viral transcripts. P22 N modifies RNA polymerase activity by creating a termination-resistant form of the RNA polymerase complex that is able to continue transcribing the viral transcript. Synonyms: H-Asn-Ala-Lys-Thr-Arg-Arg-His-Glu-Arg-Arg-Arg-Lys-Leu-Ala-Ile-Glu-Arg-OH; P22 N-(14-30); L-asparagyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-arginyl-L-histidyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-isoleucyl-L-alpha-glutamyl-L-arginine. Grades: ≥95%. Molecular formula: C90H164N40O24. Mole weight: 2190.55. | |
| p-(2,3-Epoxypropoxy)benzyl Alcohol | p-(2,3-Epoxypropoxy)benzyl Alcohol. Group: Biochemicals. Alternative Names: 4- (Oxiranylmethoxy) benzenemethanol; [4- (Oxiran-2-ylmethoxy) phenyl]methanol; p-(2,3-Epoxypropoxy)benzyl Alcohol; 4- (Oxiranylmethoxy) benzenemethanol; 4- (2-Oxiranylmethoxy) benzenemethanol. Grades: Highly Purified. CAS No. 4204-78-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| P-2563 III | P-2563 III is an antibiotic produced by Pseudomonas fluorescens P-2563. It is effective against gram-positive and gram-negative bacteria, especially against Pseudomonas. Molecular formula: C12H27N3O8. Mole weight: 341.36. | |
| p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenephosphonate | p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenephosphonate. Group: Biochemicals. Alternative Names: 5-Chloro-2-methoxy-N- [2- [4- (phosphonooxy) phenyl] ethyl] benzamide. Grades: Highly Purified. CAS No. 594854-55-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H17ClNO6P. US Biological Life Sciences. | Worldwide |
| p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid | p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid. Group: Biochemicals. Alternative Names: 4- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid; p-[2- (5-Chloro-o-anisamido) ethyl]benzenesulfonic acid. Grades: Highly Purified. CAS No. 33924-53-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H16ClNO5S. US Biological Life Sciences. | Worldwide |
| p-[[2,5-Dimethoxy-4-(phenylazo)phenyl]azo]phenol | p-[[2,5-Dimethoxy-4-(phenylazo)phenyl]azo]phenol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 232-995-4, CID5483538, p-((2,5-Dimethoxy-4-(phenylazo)phenyl)azo)phenol, Phenol, 4-((2,5-dimethoxy-4-(phenylazo)phenyl)azo)-, Phenol, 4-(2-(2,5-dimethoxy-4-(2-phenyldiazenyl)phenyl)diazenyl)-, 10000-42-7. Product Category: Heterocyclic Organic Compound. CAS No. 10000-42-7. Molecular formula: C20H18N4O3. Mole weight: 362.381920 [g/mol]. Purity: 0.96. IUPACName: 4-[(2,5-dimethoxy-4-phenyldiazenylphenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one. Canonical SMILES: COC1=CC(=C(C=C1N=NC2=CC=CC=C2)OC)NN=C3C=CC(=O)C=C3. Density: 1.22g/cm³. ECNumber: 232-995-4. Product ID: ACM10000427. Alfa Chemistry ISO 9001:2015 Certified. | |
| P2647 | P2647, also known as Benzquinamide, is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. P2647 binds to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. Uses: Antipsychotic agents; antiemetics. Synonyms: P2647; P 2647; P-2647; [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate; benzquinamide; benzquinamide hydrochloride; benzquinamide, (2alpha,3beta,11balpha)-isomer; Emite-con. CAS No. 63-12-7. Molecular formula: C22H32N2O5. Mole weight: 404.5. | |
| p-(2-Bromo)vinyl Anisole | p-(2-Bromo)vinyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| p2Ca | p2Ca, a ligand containing 8 amino acids, is naturally processed and presented to the LD heterologous T-cell clone 2C. Synonyms: H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH; L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-leucine; p2Ca peptide; L-Leucine, N-(N-(N-(1-(N-(1-(N-L-leucyl-L-seryl)-L-prolyl)-L-phenylalanyl)-L-prolyl)-L-phenylalanyl)-L-alpha-aspartyl)-. Grades: ≥95%. CAS No. 142606-55-1. Molecular formula: C47H66N8O12. Mole weight: 935.07. | |
| p-(2-Chloro)ethyl Anisole | p-(2-Chloro)ethyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| p-[(2-Chloroethyl)ethylamino]-benzaldehyde | p-[(2-Chloroethyl)ethylamino]-benzaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: P-[(2-CHLOROETHYL)ETHYLAMINO]-BENZALDEHYDE;N-ETHYL-N-CHLOROETHYL-4-AMINO BENZALDEHYDE;TIMTEC-BB SBB007673;4-[(2-chloroethyl)ethylamino]-benzaldehyde;Benzaldehyde, 4-[(2-chloroethyl)ethylamino]-;p-(N-(2-Chloroethyl)-N-ethyl)aminobenzaldehyde;4-(N-Ethyl-N-. Product Category: Heterocyclic Organic Compound. CAS No. 2643-7-4. Molecular formula: C11H14ClNO. Mole weight: 211.69. Density: 1.153g/cm³. Product ID: ACM2643074. Alfa Chemistry ISO 9001:2015 Certified. | |
| p-[(2-Chloroethyl)ethylamino]-benzaldehyde | Dark oil, 97%. CAS No. 2643-7-4. Pack Sizes: 5g, 100g. Product ID: FR-0087. Mole weight: 211.69. | Frinton Laboratories |
| P-[2-Hydroxy-1-(phenylmethoxy)propyl]phosphonic Acid Dimethyl Ester | P-[2-Hydroxy-1-(phenylmethoxy)propyl]phosphonic Acid Dimethyl Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Molecular formula: C12H19O5P. Mole weight: 274.25. | |
| P2X1 Purinergic Receptor, Control Peptide | P2X1 Purinergic Receptor, Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences. | Worldwide |
| P2X2 Receptor Control Peptide | P2X2 Receptor Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences. | Worldwide |
| P2X Antagonist III (Purinergic Receptor P2X Antagonist III, N- ( (4- (4-Phenylpiperazin-1-yl) tetrahydro-2H-pyran-4-yl) methyl) -2- (phenylthio) nicotinamide) | A phenylthio-nicotinamide that acts as a high affinity P2X7 antagonist (pKi = 8.7 and 7.9, respectively, against 30nM A-804598 for rat and human P2X7 binding) and potently inhibits P2X7-dependent cellular Ca2+ mobilization (pIC50 = 8.3, 7.5, and 7.2, respectively, using 1321N1 expressing human, mouse, or rat P2X7; drug added 0.5 h prior to 3 min 0.25 mM BzATP stimulation), while exhibiting much reduced or little potency toward a panel of 50 ion channels, transporters, and receptors. Although not suitable for oral dosing due to high hepatic extraction ratios, effective delivery and brain P2X7 occupancy can be achieved via s.c. dosing in rats (30mg/kg) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| P2Y14 Antagonist Prodrug 7j hydrochloride | A P2Y14 antagonist prodrug. Grades: 98%. CAS No. 1315308-19-0. Molecular formula: C33H32ClF3N2O3. Mole weight: 597.07. | |
| P2Y1/P2Y12 antagonist-1 | P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC 50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model. Uses: Scientific research. Group: Signaling pathways. CAS No. 2738381-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149454. | |
| P2Y Antagonist II (1- (2- (2-tert-Butylphenoxy) pyridin-3-yl) -3- (4- (trifluoromethoxy) phenyl) urea, Purinergic Receptor P2Y Antagonist II) | A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for human P2Y1 binding), while displaying much reduced or no affinity toward other P2Y family GPCRs (Ki = ≥2.5uM toward hP2Y14; Ki >15uM toward human P2Y2, P2Y6, P2Y11, and P2Y12). Effectively inhibits 2.5uM ADP-induced platelet aggregation in vitro (IC50 = 2.1uM) and reduces FeCl2-induced carotid artery blood clot formation in anesthetized rats in vivo (10mg/kg/h i.v. infusion) with much less effect toward prolonging cuticle and mesenteric bleeding time when compared to another P2Y12 antagonist Clopidogrel. Pharmackinetic studies reveal only moderate oral bioavailability in rat. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. | Worldwide |
| p300/CBP Inhibitor VI, L002 (4- (4-Methoxyphenyl sulfonyl oxyimino) -2, 6-di methyl -2, 5-cyclohexadien-1-one, GCN5 Inhibitor III, Histone Acetyltransferase Inhibitor IX, PCAF Inhibitor IV) | A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. | Worldwide |
| P3-(1-(2-Nitrophenyl)ethyl) adenosine 5?-triphosphate disodium salt | Cas No. 171800-68-3. | |
| P32/98 hemifumarate | P32/98 is a competitive dipeptidyl peptidase IV (DPP IV) inhibitor exhibiting anti-diabetic activity. Study shows that long-term treatment with P32/98 improves glucose tolerance, insulinemia, beta-cell glucose responsiveness, and peripheral insulin sensitivity. Synonyms: (2S,3S)-2-amino-3-methyl-1-(3-thiazolidinyl)-1-Pentanone (2E)-2-butenedioate (2:1). Grades: ≥98%. CAS No. 251572-86-8. Molecular formula: C9H18N2OS·1/2C4H4O4. Mole weight: 260.4. | |
| P-3355 | P-3355 is antibacterial and antifungal antibiotic produced by streptomyces amylovorus. Synonyms: Antibiotic P 3355; P 3355. CAS No. 60046-57-3. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| p-(3,5-Dichlorophenyl)phosphonic acid | p-(3,5-Dichlorophenyl)phosphonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3,5-dichlorophenyl)phosphonic Acid, SureCN4410151, AGN-PC-0078DJ, Phosphonic acid, (3,5-dichlorophenyl)-, KB-207025, 89891-38-3. Product Category: Heterocyclic Organic Compound. CAS No. 89891-38-3. Molecular formula: C6H5Cl2O3P. Mole weight: 226.981862 [g/mol]. Purity: 0.96. IUPACName: (3,5-dichlorophenyl)phosphonic acid. Canonical SMILES: C1=C(C=C(C=C1Cl)Cl)P(=O)(O)O. Product ID: ACM89891383. Alfa Chemistry ISO 9001:2015 Certified. | |
| p38α inhibitor 3 | p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 260428-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153002. | |
| p38α inhibitor 5 | p38α inhibitor 5 (compound 1) is a PROTAC-type target protein ligand targeting p38 and can be used to synthesize NR-11c (HY-159798) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2550397-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159799. | |
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