American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

Search for products or services, then visit the suppliers website for prices or more information.

Product
P005091 P005091 is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μM). P005091 induces elevated p53 and apoptosis in cancer cell lines and displays antiangiogenic activity in vivo. The deubiquitylating enzyme USP7 (HAUSP) sits at a critical node regulating the activities of numerous proteins broadly characterized as tumor suppressors, DNA repair proteins, immune responders, viral proteins, and epigenetic modulators. Aberrant USP7 activity may promote oncogenesis and viral disease making it a compelling target for therapeutic intervention. Synonyms: P005091; P-005091; P 005091; P5091; P-5091; P 5091. Grades: 0.98. CAS No. 882257-11-6. Molecular formula: C12H7Cl2NO3S2. Mole weight: 348.212. BOC Sciences 10
P005091 P005091. Group: Biochemicals. Alternative Names: 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. Molecular Formula: C12H7Cl2NO3S2, Molecular Weight: 348.22. US Biological Life Sciences. USBiological 3
Worldwide
P005091 (USP7 Inhibitor, 1-[5-[(2,3-Dichlorophenyl)thio]-4-n itro-2-thienyl]ethanone) Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2um). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 882257-11-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
P053 P053 is an inhibitor of ceramide synthase 1 (CerS1). Synonyms: (2S)-2-amino-4-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-2-methylbutan-1-ol. Grades: ≥95%. CAS No. 2748196-63-4. Molecular formula: C18H21Cl2NO2. Mole weight: 354.27. BOC Sciences 9
P1 A protein disulfide isomerase inhibitor with IC50 value of 1.7 μM. It can inhibit the proliferation of numerous cancer cell lines. Synonyms: PDI-IN-P1; PDI IN P1; PDIINP1; PDI inhibitor P1; PDI-inhibitor-P1; N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide. Grades: ≥98% by HPLC. CAS No. 1461648-55-4. Molecular formula: C30H37N3O7S. Mole weight: 583.7. BOC Sciences 9
P1075 P 1075 is a Kir6 (KATP) channel opener (EC50 for relaxation of rat aorta = 7.5 nM) by causing relaxation of various isolated animal and human blood vessels. Uses: Vasodilator agents. Synonyms: P-1075; PNU-83757; U-83757; P1075; PNU83757; U83757; P 1075; PNU 83757; U 83757; N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridylguanidine. Grades: ≥99% by HPLC. CAS No. 60559-98-0. Molecular formula: C12H17N5. Mole weight: 231.3. BOC Sciences 10
P1075 P1075. Group: Biochemicals. Grades: Purified. CAS No. 60559-98-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
P11 P11 is a potent antagonist of the integrin αvβ3-vitronectin interaction with IC50 value of 25.72 nM. Synonyms: H-His-Ser-Asp-Val-His-Lys-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-L-valyl-L-histidyl-L-lysinamide; HSDVHK-NH2. Grades: >98%. CAS No. 848644-86-0. Molecular formula: C30H48N12O9. Mole weight: 720.78. BOC Sciences 3
P110 TFA P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor that inhibits Drp1 GTPase activity. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2.TFA; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-glycyl-glycyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-prolyl-L-arginyl-glycyl-L-serinamide trifluoroacetic acid; Dynamic-related protein 1 (Drp-1)-specific inhibitor P110 trifluoroacetate; P 110 (peptide) trifluoroacetate; P 110 TFA; P-110 TFA. Grades: ≥95%. Molecular formula: C102H180F3N45O27. Mole weight: 2525.80. BOC Sciences 6
P- (1, 1, 2, 2, 3, 3, 4, 4, 5, 5, 6, 6, 7, 7, 8, 8, 8-heptadecafluorooctyl) phosphonic Acid 4-Methylbenzeneamine Salt P- (1, 1, 2, 2, 3, 3, 4, 4, 5, 5, 6, 6, 7, 7, 8, 8, 8-heptadecafluorooctyl) phosphonic Acid 4-Methylbenzeneamine Salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 1263361-03-0. Pack Sizes: 25mg. Molecular Formula: C15H11F17O3NP, Molecular Weight: 607.2. US Biological Life Sciences. USBiological 3
Worldwide
p-(1,1,3,3-Tetramethylbutyl)phenol Purity 98%, white crystalline. Synonyms: 4-tert-Octylphenol. CAS No. 140-66-9. Pack Sizes: 10g, 50g. Product ID: FR-0872. M.P. 83-85. Mole weight: 206.33. Frinton Laboratories Inc
Frinton Laboratories
P11 (His-Ser-Asp-Val-His-Lys-NH2, Potent antagonist of alphavbeta3-vitronectin Interaction, Antiangiogenic) Potent antagonist of the integrin avb3-vitronectin interaction (IC50 = 25.72nm). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 848644-86-0. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
P-(1,2-Dihydroxypropyl)phosphonic Acid Cas No. 84954-80-3. BOC Sciences 8
P-132 P-132 is an antibiotic produced by Microbispora P-132, W-17 and 37-26. It is effective against gram-positive bacteria, fungi and actinomycetes. Synonyms: P 132. Molecular formula: C14H10N2O3. Mole weight: 254.24. BOC Sciences 5
p14ARF-ORF3 (125-133) BOC Sciences 3
P15 P15 is an antimicrobial peptide found in Cervus elaphus (New Zealand red deer), and has antimicrobial activity against gram-negative bacterium Escherichia coli O111 (MIC=0.3 μg/mL), gram-positive bacterium Staphylococcus aureus NCTC 4163 (MIC=1 μg/mL) and Fungi Candida albicans 3135A (MIC=3 μg/mL). Synonyms: deer beta-defensin. Grades: >98%. BOC Sciences 4
P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt. Group: Biochemicals. Alternative Names: AP3A. Grades: Highly Purified. CAS No. 5959-90-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H27N10O16P3. US Biological Life Sciences. USBiological 8
Worldwide
P-18 P-18 is an antimicrobial peptide with anti-gram-positive bacteria, gram-negative bacteria, Cancer cells and Mammalian cells activity. The source of P-18 is Sequence reverse. Synonyms: Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Pro-Lys-Phe-Leu-His-Leu-Ala-Lys-Lys-Phe; Cecropin A(1-8)-Magainin 2(1-12) hybrid peptide analogue; P18. Grades: ≥98%. Molecular formula: C118H186N28O19. Mole weight: 2300.95. BOC Sciences 4
P1 Antigen P1 Antigen, a complex carbohydrate antigen located on red blood cells, allows for investigation of blood groupings and H antigen expression, with potential implications for transfusion reactions. Moreover, it is highly relevant in cutting-edge research pertaining to red blood cell-associated disorders, including sickle cell anemia. Synonyms: alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-GlcNAc; Galα1-4Galβ1-4-GlcNAc; alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine; alpha-D-galactopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranose; O-α-D-Galactopyranosyl-(1->4)-O-β-D-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-D-glucose; 2-Acetamido-2-deoxy-4-O-([4-O-β-D-galactopyranosyl]-β-D-galactopyranosyl)-D-glucopyranose. Grades: ≥95%. CAS No. 54832-51-8. Molecular formula: C20H35NO16. Mole weight: 545.49. BOC Sciences 12
P1-Antigen P1-Antigen is a crucial biomarker in the biomedical industry used for the research of diseases such as certain types of cancers. It aids in identifying the presence of specific antigens and their related antibodies in developing targeted research strategies. Synonyms: Gal-a1,4-Gal-b1,4-GlcNAc; 2-Acetamido-2-deoxy-4-O-([4-O-b-D-galactopyranosyl]-b-D-galactopyranosyl)-D-glucopyranose. Molecular formula: C20H35NO16. Mole weight: 545.49. BOC Sciences 12
P1, Human It is a cell-penetrating peptide (CPP) derived from the human immunoglobulin heavy chain sequence. At low molar concentration, it can permeate cell membrane without obvious influence on cell membrane. CPP can bind macromolecules and be used as drug delivery vectors. Synonyms: H-Met-Gly-Leu-Gly-Leu-His-Leu-Leu-Val-Leu-Ala-Ala-Ala-Leu-Gln-Gly-Ala-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val-OH; Human P1. Grades: 97%. Molecular formula: C134H229N39O31S. Mole weight: 2914.61. BOC Sciences 4
P1 (N-[ (1, 1-Dimethylethoxy) carbonyl]-L-phenylalanyl-O- (ethenylsulfonyl) -N-4-pentyn-1-yl-L-tyrosinamide) Protein disulfide isomerase (PDI) inhibitor (IC50 = 1.7uM). Inhibits proliferation of numerous cancer cell lines. Cell permeable. Group: Biochemicals. Grades: Highly Purified. CAS No. 1461648-55-4. Pack Sizes: 1mg. Molecular Formula: C30H37N3O7S, Molecular Weight: 583.7. US Biological Life Sciences. USBiological 5
Worldwide
P1,P2-DI(GUANOSINE-5) DIPHOSPHATEAMMONI UM Heterocyclic Organic Compound. CAS No. 102783-41-5. Purity: 0.96. Catalog: ACM102783415. Alfa Chemistry. 3
P1,P4-Di(adenosine-5') Tetraphosphate Ammonium Salt P1,P4-Di(adenosine-5') Tetraphosphate Ammonium Salt, a derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes. Synonyms: Adenosine 5'-(Pentahydrogen Tetraphosphate) P'''?5'-Ester with Adenosine Tetraammonium Salt; Adenosine 5'-(Pentahydrogen Tetraphosphate) P'''?5'-Ester with Adenosine Ammonium Salt. Grades: 95%. CAS No. 102783-36-8. Molecular formula: C20H28N10O19P4 xNH3. Mole weight: 836.39. BOC Sciences 3
p1,p4-Di(adenosine-5')tetraphosphate,periodate oxidized sodium salt Heterocyclic Organic Compound. CAS No. 112968-03-3. Molecular formula: C20H24N10O19P4. Catalog: ACM112968033. Alfa Chemistry.
p1,p4-Di(guanosine-5')tetraphosphate ammonium salt Heterocyclic Organic Compound. Alternative Names: P1,P4-Di(guanosine-5) tetraphosphate ammonium salt, 102783-33-5, D1028_SIGMA, CTK8F1002, G(5 inverted exclamation marka)P4(5 inverted exclamation marka)G, P1,P4-Di(guanosine-5 inverted exclamation marka) tetraphosphate ammonium salt. CAS No. 102783-33-5. Molecular formula: C20H28N10O21P4. Mole weight: 868.39. Purity: 0.96. IUPACName: azanium;[[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Canonical SMILES: C1=NC2=C (N1C3C (C (C (O3)COP (=O) (O)OP (=O) (O)OP (=O) (O)OP (=O) (O)OCC4C (C (C (O4)N5C=NC6=C5NC (=NC6=O)N)O)O)O)O)NC (=NC2=O)N. [NH4+]. Catalog: ACM102783335. Alfa Chemistry. 3
p1,p5-Di(adenosine-5')pentaphosphate,periodate oxidized sodium salt Heterocyclic Organic Compound. Alternative Names: D9031_SIGMA, P1,P5-Di(adenosi 2,3-dialdehyde-5) pentaphosphate, P1,P5-Di(adenosine-5) pentaphosphate, periodate oxidized sodium salt, 107148-01-6, P1,P5-Di(adenosi 2 inverted exclamation marka,3 inverted exclamation marka-dialdehyde-5 inverted exclamation marka) pentaphosphate, P1,P5-Di(adenosine-5 inverted exclamation marka) pentaphosphate, periodate oxidized sodium salt. CAS No. 107148-01-6. Molecular formula: C20H25N10O22P5•xNa+. Mole weight: 912.34 (free acid basis). Purity: 0.96. IUPACName: bis[[[2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-oxopropoxy]-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate;sodium. Catalog: ACM107148016. Alfa Chemistry. 4
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5?-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. Group: Biochemicals. Alternative Names: P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, 94108-02-8, A(5)P5(5)A, AC1O4WDE, D6392_SIGMA, CTK8G2238, EINECS 302-339-2, AP5A lithium salt P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, AG-H-86941, Diadenosine pentaphosphate trilithium salt, Diadenosine pentaphosphate pentalithium salt, K00187, A(5 inverted exclamation marka)P5(5 inverted exclamation marka)A trilithium sal. Grades: Highly Purified. CAS No. 75522-97-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H26N10O22P5Li3, Molecular Weight: 934.17. US Biological Life Sciences. USBiological 8
Worldwide
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt P1,P5-Di(adenosine-5')pentaphosphate trilithium salt is an indispensable biomedical compound, proficiently assuming the role of a robust purinergic receptor agonist, significantly impacting diverse cellular processes. This compound emerges as an invaluable tool in the research of neurological disorders, cancer and cardiovascular diseases. Synonyms: Ap5a. CAS No. 75522-97-3. Molecular formula: C20H26N10O22P5Li3. Mole weight: 934.17. BOC Sciences 2
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC) P1,P5-Di(adenosine-5')pentaphosphate trilithium salt ≥96% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g, 25g. US Biological Life Sciences. USBiological 5
Worldwide
p1,p5-Di(guanosine-5')pentaphosphate ammonium salt Heterocyclic Organic Compound. Alternative Names: Diguanosine pentaphosphate, 102783-42-6, G(5 inverted exclamation marka]P5(5 inverted exclamation marka)G, P1,P5-Di(guanosine-5 inverted exclamation marka) pentaphosphate ammonium salt. CAS No. 102783-42-6. Molecular formula: C20H29N10O24P5. Mole weight: 948.37. Purity: 0.96. IUPACName: azane;bis[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Canonical SMILES: C1=NC2=C (N1C3C (C (C (O3)COP (=O) (O)OP (=O) (O)OP (=O) (O)OP (=O) (O)OP (=O) (O)OCC4C (C (C (O4)N5C=NC6=C5NC (=NC6=O)N)O)O)O)O)NC (=NC2=O)N. N. Catalog: ACM102783426. Alfa Chemistry. 3
p-(1-Piperidino)acetophenone Crystalline. Synonyms: N-(4-Acetylphenyl)piperidine. CAS No. 10342-85-5. Pack Sizes: 5g. Product ID: FR-0935. M.P. 88-89. Mole weight: 203.29. Frinton Laboratories Inc
Frinton Laboratories
P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt. Group: Biochemicals. Alternative Names: Fosfomycin EP-Impurity A. Grades: Highly Purified. CAS No. 1160525-87-0. Pack Sizes: 50mg. Molecular Formula: C3H9O5P, Molecular Weight: 156.07. US Biological Life Sciences. USBiological 3
Worldwide
P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Phosphonic acid, P-[(1R,2R)-1,2-dihydroxypropyl]-, ammonium salt (1:?). CAS No. 1160525-87-0. IUPAC Name: azane;[(1R,2R)-1,2-dihydroxypropyl]phosphonic acid. Molecular Formula: C3H9O5P.2H3N. Mole Weight: 190.14. Catalog: APS1160525870. SMILES: N.N.C[C@@H](O)[C@H](O)P(=O)(O)O. Format: Neat. Alfa Chemistry Analytical Products
P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: 1160525-87-0; Diazanium; (1R,2R)-1-phosphonatopropane-1,2-diolP-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt((1R,2R)-1,2-Dihydroxypropyl)phosphonate xammonium saltstarbld0003549. CAS No. 1160525-87-0. Molecular formula: C3H9O5P.xNH3. Mole weight: 156.07 (free base). BOC Sciences 8
P-[(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester P-[(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin intermediates. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: Phosphonic acid, P-[(1R,2R)-1,2-dihydroxypropyl]-, bis(phenylmethyl) ester; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester; Dibenzyl ((1R,2R)-1,2-dihydroxypropyl)phosphonate; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic acid dibenzyl ester. Molecular formula: C17H21O5P. Mole weight: 336.32. BOC Sciences 8
P-[ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester P-[ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: [ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester. Molecular formula: C24H27O7PS. Mole weight: 490.50. BOC Sciences 8
P-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic Acid Monoethyl Ester Intermediate in the synthesis of Tenofovir impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1255525-18-8. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
P2045 P2045 is a somatostatin analog cyclopeptide. Rhenium Re188 P2045 is the Rhenium complex of P2045. Phase I clinical trials demonstrated that Re-188 P2045 was well tolerated. Tc-99m P2045 imaging allows identification of patients who may benefit from this treatment. Although responses were not seen, survival for these heavily pretreated patients is interesting and merits further research. Synonyms: P 2045; P-2045; Cyclo(N-methyl-L-homocysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl), (11')-thioether with 3-[(2-mercaptoacetyl)amino]-L-alanyl-4-amino-L-phenylalanyl-L-cysteinyl-L-threonyl-L-serine. CAS No. 259746-53-7. Molecular formula: C68H91N15O17S2. Mole weight: 1454.68. BOC Sciences 11
p21-Activated Kinase Inhibitor II, PF-3758309 (PAK Inhibitor II, PF3758309, (S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-(2-methylthieno[3,2-d]pyrimidin-4-ylamino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide) A cell-permeable pyrrolopyrazole that acts as a potent inhibitor against p21-activated kinases (Ki innM/[ATP] inuM = 13.7/200, 18.7/40, 18.1/80. 17.1/72, respectively, in PAK1, PAK4, PAK5, PAK6 kinase assays; IC50 = 190 and 99nM against PAK1 and PAK3, respectively) by directly targeting the kinase ATP-binding site in a reversible manner (Kd = 4.5nM using rhPAK4300-591 kinase domain). Inhibits PAK4-dependent cellular signaling (IC50 = 24.2nM against TNFalpha-stimulated NF-kappa-B activity in HEK293T) and proliferation (IC50 = 0.24 and 27nM, respectively, against HCT116 and A549 colonies formation) in vitro and the growth of human tumors in nude mice in vivo (10 to 25mg/kg; b.i.d. p.o). Group: Biochemicals. Grades: Highly Purified. CAS No. 898044-15-0. Pack Sizes: 5mg. Molecular Formula: C??H??N?OS. US Biological Life Sciences. USBiological 4
Worldwide
P21d hydrochloride P21d hydrochloride is a breast tumor kinase inhibitor with IC50 value of 30 nM. It can restore E-cadherin expression and suppress migration in breast cancer cells. Synonyms: [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-4-morpholinylmethanone hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C23H22FN7O2.HCl. Mole weight: 483.93. BOC Sciences 9
P22077 P22077 is a potent and selective ubiquitin-specific protease 7 (USP7) inhibitor. P22077 potently induces apoptosis in NB cells with an intact USP7-HDM2-p53 axis but not in NB cells with mutant p53 or without human homolog of MDM2 (HDM2) expression. P22077 was found to be able to sensitize chemoresistant LA-N-6 NB cells to chemotherapy. In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines. USP7-specific inhibitors like P22077 may serve not only as a stand-alone therapy but also as an effective adjunct to current chemotherapeutic regimens for treating NB with an intact USP7-HDM2-p53 axis. Synonyms: P-22077; P 22077. Grades: 0.98. CAS No. 1247819-59-5. Molecular formula: C12H7F2NO3S2. Mole weight: 315.309. BOC Sciences 9
P 22077 P 22077. Group: Biochemicals. Grades: Purified. CAS No. 1247819-59-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
P22 N (14-30) The peptide sequence is found in residues 14 to 30 of P22 N. P22 N is a transcriptional antiterminator that binds to N-utilization (NUT) sites on viral transcripts. P22 N modifies RNA polymerase activity by creating a termination-resistant form of the RNA polymerase complex that is able to continue transcribing the viral transcript. Synonyms: H-Asn-Ala-Lys-Thr-Arg-Arg-His-Glu-Arg-Arg-Arg-Lys-Leu-Ala-Ile-Glu-Arg-OH; P22 N-(14-30); L-asparagyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-arginyl-L-histidyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-isoleucyl-L-alpha-glutamyl-L-arginine. Grades: ≥95%. Molecular formula: C90H164N40O24. Mole weight: 2190.55. BOC Sciences 4
p-(2,3-Epoxypropoxy)benzyl Alcohol p-(2,3-Epoxypropoxy)benzyl Alcohol. Group: Biochemicals. Alternative Names: 4- (Oxiranylmethoxy) benzenemethanol; [4- (Oxiran-2-ylmethoxy) phenyl]methanol; p-(2,3-Epoxypropoxy)benzyl Alcohol; 4- (Oxiranylmethoxy) benzenemethanol; 4- (2-Oxiranylmethoxy) benzenemethanol. Grades: Highly Purified. CAS No. 4204-78-8. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 3
Worldwide
p-[(2,4-Diaminophenyl)azo]benzenesulfonamide Heterocyclic Organic Compound. Alternative Names: Sulfamidochrysoidine; 4-sulfamyl-2,4-diaminoazobenzene; Prontosil rubrum; Aseptil rojo (TN); 4-[ (2, 4-diaminophenyl) diazenyl]benzenesulfonamide; 4-[ (2, 4-diaminophenyl) azo]-benzenesulfonamide; 2.4-Diamino-azobenzol-sulfonsaeure-(4)-amid; 4-(2,4-diamino-phen. CAS No. 103-12-8. Molecular formula: C12H13N5O2S. Mole weight: 291.328920 [g/mol]. Purity: 0.96. IUPACName: 4-[ (2, 4-diaminophenyl) diazenyl]benzenesulfonamide. Density: 1.54g/cm³. Catalog: ACM103128. Alfa Chemistry. 5
P-2563 III P-2563 III is an antibiotic produced by Pseudomonas fluorescens P-2563. It is effective against gram-positive and gram-negative bacteria, especially against Pseudomonas. Molecular formula: C12H27N3O8. Mole weight: 341.36. BOC Sciences 5
p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenephosphonate p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenephosphonate. Group: Biochemicals. Alternative Names: 5-Chloro-2-methoxy-N- [2- [4- (phosphonooxy) phenyl] ethyl] benzamide. Grades: Highly Purified. CAS No. 594854-55-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H17ClNO6P. US Biological Life Sciences. USBiological 6
Worldwide
p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid p- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid. Group: Biochemicals. Alternative Names: 4- [2- [ (5-Chloro-2-methoxybenzoyl) amino] ethyl] benzenesulfonic acid; p-[2- (5-Chloro-o-anisamido) ethyl]benzenesulfonic acid. Grades: Highly Purified. CAS No. 33924-53-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H16ClNO5S. US Biological Life Sciences. USBiological 6
Worldwide
p-[[2,5-Dimethoxy-4-(phenylazo)phenyl]azo]phenol Heterocyclic Organic Compound. Alternative Names: EINECS 232-995-4, CID5483538, p-((2,5-Dimethoxy-4-(phenylazo)phenyl)azo)phenol, Phenol, 4-((2,5-dimethoxy-4-(phenylazo)phenyl)azo)-, Phenol, 4-(2-(2,5-dimethoxy-4-(2-phenyldiazenyl)phenyl)diazenyl)-, 10000-42-7. CAS No. 10000-42-7. Molecular formula: C20H18N4O3. Mole weight: 362.381920 [g/mol]. Purity: 0.96. IUPACName: 4-[ (2, 5-dimethoxy-4-phenyldiazenylphenyl) hydrazinylidene]cyclohexa-2, 5-dien-1-one. Canonical SMILES: COC1=CC (=C (C=C1N=NC2=CC=CC=C2)OC)NN=C3C=CC (=O)C=C3. Density: 1.22g/cm³. ECNumber: 232-995-4. Catalog: ACM10000427. Alfa Chemistry. 2
P2647 P2647, also known as Benzquinamide, is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. P2647 binds to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. Uses: Antipsychotic agents; antiemetics. Synonyms: P2647; P 2647; P-2647; [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate; benzquinamide; benzquinamide hydrochloride; benzquinamide, (2alpha,3beta,11balpha)-isomer; Emite-con. CAS No. 63-12-7. Molecular formula: C22H32N2O5. Mole weight: 404.5. BOC Sciences 10
p-(2,6-Difluorophenyl)phosphonic acid Heterocyclic Organic Compound. Alternative Names: SureCN10072934, (2,6-difluorophenyl)phosphonic acid, KB-205728, 1206195-94-9. CAS No. 1206195-94-9. Molecular formula: C6H5F2O3P. Mole weight: 194.072668 [g/mol]. Purity: 0.96. IUPACName: (2,6-difluorophenyl)phosphonic acid. Canonical SMILES: C1=CC(=C(C(=C1)F)P(=O)(O)O)F. Catalog: ACM1206195949. Alfa Chemistry. 3
p-(2-Bromo)vinyl Anisole p-(2-Bromo)vinyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. USBiological 1
Worldwide
p2Ca p2Ca, a ligand containing 8 amino acids, is naturally processed and presented to the LD heterologous T-cell clone 2C. Synonyms: H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH; L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-leucine; p2Ca peptide; L-Leucine, N-(N-(N-(1-(N-(1-(N-L-leucyl-L-seryl)-L-prolyl)-L-phenylalanyl)-L-prolyl)-L-phenylalanyl)-L-alpha-aspartyl)-. Grades: ≥95%. CAS No. 142606-55-1. Molecular formula: C47H66N8O12. Mole weight: 935.07. BOC Sciences 3
p-(2-Chloro)ethyl Anisole p-(2-Chloro)ethyl Anisole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 1
Worldwide
p-[(2-Chloroethyl)ethylamino]-benzaldehyde Dark oil, 97%. CAS No. 2643-7-4. Pack Sizes: 5g, 100g. Product ID: FR-0087. Mole weight: 211.69. Frinton Laboratories Inc
Frinton Laboratories
P-[2-Hydroxy-1-(phenylmethoxy)propyl]phosphonic Acid Dimethyl Ester P-[2-Hydroxy-1-(phenylmethoxy)propyl]phosphonic Acid Dimethyl Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Molecular formula: C12H19O5P. Mole weight: 274.25. BOC Sciences 8
P2X1 Purinergic Receptor, Control Peptide P2X1 Purinergic Receptor, Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences. USBiological 1
Worldwide
P2X2 Receptor Control Peptide P2X2 Receptor Control Peptide. Group: Molecular Biology. Pack Sizes: 40ug. US Biological Life Sciences. USBiological 1
Worldwide
P2X Antagonist III (Purinergic Receptor P2X Antagonist III, N- ( (4- (4-Phenylpiperazin-1-yl) tetrahydro-2H-pyran-4-yl) methyl) -2- (phenylthio) nicotinamide) A phenylthio-nicotinamide that acts as a high affinity P2X7 antagonist (pKi = 8.7 and 7.9, respectively, against 30nM A-804598 for rat and human P2X7 binding) and potently inhibits P2X7-dependent cellular Ca2+ mobilization (pIC50 = 8.3, 7.5, and 7.2, respectively, using 1321N1 expressing human, mouse, or rat P2X7; drug added 0.5 h prior to 3 min 0.25 mM BzATP stimulation), while exhibiting much reduced or little potency toward a panel of 50 ion channels, transporters, and receptors. Although not suitable for oral dosing due to high hepatic extraction ratios, effective delivery and brain P2X7 occupancy can be achieved via s.c. dosing in rats (30mg/kg) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
P2Y14 Antagonist Prodrug 7j hydrochloride A P2Y14 antagonist prodrug. Grades: 98%. CAS No. 1315308-19-0. Molecular formula: C33H32ClF3N2O3. Mole weight: 597.07. BOC Sciences 11
P2Y Antagonist II (1- (2- (2-tert-Butylphenoxy) pyridin-3-yl) -3- (4- (trifluoromethoxy) phenyl) urea, Purinergic Receptor P2Y Antagonist II) A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for human P2Y1 binding), while displaying much reduced or no affinity toward other P2Y family GPCRs (Ki = ≥2.5uM toward hP2Y14; Ki >15uM toward human P2Y2, P2Y6, P2Y11, and P2Y12). Effectively inhibits 2.5uM ADP-induced platelet aggregation in vitro (IC50 = 2.1uM) and reduces FeCl2-induced carotid artery blood clot formation in anesthetized rats in vivo (10mg/kg/h i.v. infusion) with much less effect toward prolonging cuticle and mesenteric bleeding time when compared to another P2Y12 antagonist Clopidogrel. Pharmackinetic studies reveal only moderate oral bioavailability in rat. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. USBiological 4
Worldwide
p300/CBP Inhibitor VI, L002 (4- (4-Methoxyphenyl sulfonyl oxyimino) -2, 6-di methyl -2, 5-cyclohexadien-1-one, GCN5 Inhibitor III, Histone Acetyltransferase Inhibitor IX, PCAF Inhibitor IV) A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. USBiological 4
Worldwide
P3-(1-(2-Nitrophenyl)ethyl) adenosine 5?-triphosphate disodium salt Cas No. 171800-68-3. BOC Sciences 2
P32/98 hemifumarate P32/98 is a competitive dipeptidyl peptidase IV (DPP IV) inhibitor exhibiting anti-diabetic activity. Study shows that long-term treatment with P32/98 improves glucose tolerance, insulinemia, beta-cell glucose responsiveness, and peripheral insulin sensitivity. Synonyms: (2S,3S)-2-amino-3-methyl-1-(3-thiazolidinyl)-1-Pentanone (2E)-2-butenedioate (2:1). Grades: ≥98%. CAS No. 251572-86-8. Molecular formula: C9H18N2OS·1/2C4H4O4. Mole weight: 260.4. BOC Sciences 10
P-3355 P-3355 is antibacterial and antifungal antibiotic produced by streptomyces amylovorus. Synonyms: Antibiotic P 3355; P 3355. CAS No. 60046-57-3. Molecular formula: C7H9NO2. Mole weight: 139.15. BOC Sciences 5
p-(3,5-Difluorophenyl)phosphonic acid Heterocyclic Organic Compound. Alternative Names: SCHEMBL10072928, P-(3,5-difluorophenyl)Phosphonic acid, DB-061759, 1206195-93-8. CAS No. 1206195-93-8. Molecular formula: C6H5F2O3P. Mole weight: 194.072668 [g/mol]. Purity: 0.96. IUPACName: (3,5-difluorophenyl)phosphonic acid. Canonical SMILES: C1=C(C=C(C=C1F)P(=O)(O)O)F. Catalog: ACM1206195938. Alfa Chemistry. 3
p38 MAPK-IN-1 p38 MAPK-IN-1, a naphthyridine N-oxide, is a novel potent and selective inhibitor of p38 MAPK and it was found to have proper balance between potency and pharmacokinetics and excellent action in a chronic model of arthritis for further study in some sorts. Uses: P38 mapk-in-1 is a novel potent and selective inhibitor of p38 mapk and could be useful in studying some sorts of inflammatory conditions. Synonyms: p38alpha-IN-4; p38alpha IN 4; p38alphaIN4; p38alpha inhibitor 4; p38alpha-inhibitor-4; p38 MAP Kinase Inhibitor XI; P38 MAPK-IN-1; CHEMBL1916344; SCHEMBL2077831; BDBM50357886; HY-12839; HY 12839; HY12839. Grades: 95%. CAS No. 1006378-90-0. Molecular formula: C21H15F2N2O. Mole weight: 349.35. BOC Sciences 10
p38 MAPK-IN-2 An inhibitor of p38 kinase. Synonyms: Ethanone, 1-[4-[5-(4-chloro-2-fluorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl]-1-piperidinyl]-2-hydroxy-; 1-[4-[3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl]-2-hydroxyethanone. CAS No. 635725-16-5. Molecular formula: C20H19ClFN5O2. Mole weight: 415.85. BOC Sciences 10
p38 MAP Kinase Inhibitor XI (4-(2,4-Difluorophenyl)-8-(2-methylphenyl)-1,7-naphthyridine-7-oxide, 4-(2,4-Difluorophenyl)-8-o-tolyl-1,7-naphthyridine-7-oxide) A cell-permeable naphthyridine N-oxide compound that acts as a potent, reversible p38alpha MAP kinase inhibitor (IC50 = 68nM) and exhibits excellent selectivity among 54-kinases. It acts on the ATP-binding site plus an adjacent hydrophobic pocket. Exhibits desirable ADME (Absorption, Distribution, Metabolism, and Excretion) profile with good microsomal stability, low toxicity, and low reactivity towards cytochrome P450 isozymes. Shown to inhibit lipopolysaccharide-induced TNF-alpha production in a dose-dependent manner (ED50 of 0.5mg/kg). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide