A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 260428-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153002.
p38α inhibitor 5
p38α inhibitor 5 (compound 1) is a PROTAC-type target protein ligand targeting p38 and can be used to synthesize NR-11c (HY-159798) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2550397-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159799.
p38 MAPK-IN-1
p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability. Uses: Scientific research. Group: Signaling pathways. CAS No. 1006378-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12839.
p38 MAPK-IN-4
p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 219138-24-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-112466.
p38 MAP Kinase Inhibitor - CAS 219138-24-6
The p38 MAP Kinase Inhibitor, also referenced under CAS 219138-24-6, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor III - CAS 581098-48-8
The p38 MAP Kinase Inhibitor III, also referenced under CAS 581098-48-8, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor IV
p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC 50 s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638-41-1. Pack Sizes: 5 mg. Product ID: HY-112401.
The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor V - CAS 271576-77-3
The p38 MAP Kinase Inhibitor V, also referenced under CAS 271576-77-3, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2
The p38 MAP Kinase Inhibitor VIII, also referenced under CAS 321351-00-2, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7
The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9
The p38 MAP Kinase Inhibitor VI, JX401, also referenced under CAS 349087-34-9, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor X, BIRB 796 - CAS 285983-48-4
The p38 MAP Kinase Inhibitor X, BIRB 796, also referenced under CAS 285983-48-4, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
p38 MAP Kinase Inhibitor XI (4-(2,4-Difluorophenyl)-8-(2-methylphenyl)-1,7-naphthyridine-7-oxide, 4-(2,4-Difluorophenyl)-8-o-tolyl-1,7-naphthyridine-7-oxide)
A cell-permeable naphthyridine N-oxide compound that acts as a potent, reversible p38alpha MAP kinase inhibitor (IC50 = 68nM) and exhibits excellent selectivity among 54-kinases. It acts on the ATP-binding site plus an adjacent hydrophobic pocket. Exhibits desirable ADME (Absorption, Distribution, Metabolism, and Excretion) profile with good microsomal stability, low toxicity, and low reactivity towards cytochrome P450 isozymes. Shown to inhibit lipopolysaccharide-induced TNF-alpha production in a dose-dependent manner (ED50 of 0.5mg/kg). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A cell-permeable phenylamino-dibenzosuberone-diol with a rigid molecular structure specifically designed to target hydrophobic region I in p38alpha & p38beta, but not in other kinases with bulky entrance-blocking gatekeeper residues. Shown to selectively inhibit p38alpha (IC50 = 5nM; [ATP] = 100uM) and p38beta (97% inhibition at 1uM), while exhibiting little affinity toward 400 other kinase constructs, including p38delta, p38upsilon, Erk1/2/3/4/5/8, JNK1/2/3, and MEK1/2/3/4/6. Shown to prevent cellular HSP27 Ser82 phosphorylation upon p38 activation by Anisomycin in HeLa (IC50 = 25nM) or by TNF-alpha in THP-1 cultures. Unlike the ATP-binding site-targeting BIRB 796 and SB 203580, Skepinone-L does not inhibit JNK-mediated c-Jun or ERK-dependent CREB phosphorylation in THP-1 cultures. Oral administration to D-Gal-sensitized mice is reported to greatly reduce plasma TNF-alpha production upon LPS challenge (by 77%; 3mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
P- [ (3-Bromo-7-cyano-2-naphthalenyl) difluoromethyl] phosphonic Acid. Group: Biochemicals. Alternative Names: [ (3-Bromo-7-cyano-2-naphthalenyl) difluoromethyl] phosphonic Acid. Grades: Highly Purified. CAS No. 809272-64-8. Pack Sizes: 1mg. Molecular Formula: C12H7BrF2NO3P, Molecular Weight: 362.06. US Biological Life Sciences.
Worldwide
P3HT
P3HT. Uses: Designed for use in research and industrial production. Product Category: Dye-Sensitized Solar Cell (DSSC). CAS No. 104934-50-1. Product ID: ACM104934501. Alfa Chemistry ISO 9001:2015 Certified.
p-[[4-[Bis(2-hydroxyethyl)amino]-O-tolyl]azo]-N-(2-chloroethyl)benzenesulphonamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-[[4-[bis(2-hydroxyethyl)amino]-o-tolyl]azo]-N-(2-chloroethyl)benzenesulphonamide;4-[[4-[Bis(2-hydroxyethyl)amino]-2-methylphenyl]azo]-N-(2-chloroethyl)benzenesulfonamide;Benzenesulfonamide, 4-((4-(bis(2-hydroxyethyl)amino)-2-methylphenyl)azo)-N-(2-chlo. Product Category: Heterocyclic Organic Compound. CAS No. 14607-25-1. Molecular formula: C19H25ClN4O4S. Mole weight: 440.9442. Product ID: ACM14607251. Alfa Chemistry ISO 9001:2015 Certified. Categories: EINECS 238-644-1.
P51 Polycarbonate 3D Printing Filament. Group: 3d printing materials.
p52 human
recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p53 (103-111)
P53 has been described as ''the guardian of the genome'' because of its role in conserving stability by preventing genome mutation. Suppression of p53 in human breast cancer cells is shown to lead to increased CXCR5 chemokine receptor gene expression and activated cell migration in response to chemokine CXCL13. Synonyms: Cellular tumor antigen p53 (103-111); NY-CO-13 (103-111); Tumor suppressor p53 (103-111).
p53 (1-342) C-terminal deletion human
recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p53 (139-147)
P53 has been described as ''the guardian of the genome'' because of its role in conserving stability by preventing genome mutation. Suppression of p53 in human breast cancer cells is shown to lead to increased CXCR5 chemokine receptor gene expression and activated cell migration in response to chemokine CXCL13. Synonyms: Cellular tumor antigen p53 (139-147); NY-CO-13 (139-147); Tumor suppressor p53 (139-147).
p53 (149-157)
P53 has been described as ''the guardian of the genome'' because of its role in conserving stability by preventing genome mutation. Suppression of p53 in human breast cancer cells is shown to lead to increased CXCR5 chemokine receptor gene expression and activated cell migration in response to chemokine CXCL13. Synonyms: Cellular tumor antigen p53 (149-157); NY-CO-13 (149-157); Tumor suppressor p53 (149-157).
p53 17-26
P53 (17-26) is the 17-26 amino acid fragment of P53. P53 (17-26) is the mdm-2-binding domain. Synonyms: H-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-OH; L-alpha-glutamyl-L-threonyl-L-phenylalanyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-tryptophyl-L-lysyl-L-leucyl-L-leucine; (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-indol-3-yl)methyl)-29-amino-8-(4-aminobutyl)-23-benzyl-17-(carboxymethyl)-26-((R)-1-hydroxyethyl)-20-(hydroxymethyl)-2,5,14-triisobutyl-4,7,10,13,16,19,22,25,28-nonaoxo-3,6,9,12,15,18,21,24,27-nonaazadotriacontane-1,32-dioic acid. Grade: ≥95%. CAS No. 488118-64-5. Molecular formula: C60H90N12O17. Mole weight: 1251.43.
p53 (1-81), mutant, GST tagged human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p53 (1-81), wild type, GST tagged human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is an inhibitor of the interaction between p53 and MDM2 proteins. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070009-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-70027A.
p53-MDM2-IN-1
p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an K i value of 23.35 μM. p53-MDM2-IN-1 can be used for anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 381717-91-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W340839.
p53-MDM2-IN-4
p53-MDM2-IN-4 (Example 4) is an inhibitor of p53-MDM2/X protein interaction, with a K i value of 3.079 μM. p53-MDM2-IN-4 can be used in anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350678-63-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W340313.
p53-Snail binding Inhibitor, GN25
The p53-Snail binding Inhibitor, GN25 controls the biological activity of p53-Snail. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy.
p5 Ligand for Dnak and DnaJ
It is a high affinity ligand for DnaK and DnaJ and corresponds to the main binding site of the 23 residues part of the prosequence of mitochondrial aspartate aminotransferase. Synonyms: Peptide p5; H-Cys-Leu-Leu-Leu-Ser-Ala-Pro-Arg-Arg-OH; L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-seryl-L-alanyl-L-prolyl-L-arginyl-L-arginine; 2-[(2S)-2-({[(2S)-1-{N-[(2S,5S,8S,11S,14R)-14-Amino-1,4,7,10,13-pentahydroxy-2-(hydroxymethyl)-5,8,11-triisobutyl-15-sulfanyl-3,6,9,12-tetraazapentadeca-3,6,9,12-tetraen-1-ylidene]-L-alanyl}-2-pyrrolidinyl](hydroxy)methylene}amino)-5-carbamimidamido-1-hydroxypentylidene]-L-arginine. Grade: ≥95%. CAS No. 209518-24-1. Molecular formula: C44H81N15O11S. Mole weight: 1028.27.
p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40) and corresponds to the main binding site of the 23 residues part of the prosequence of mitochondrial aspartate aminotransferase. Synonyms: H-Cys-Leu-Leu-Leu-Ser-Ala-Pro-Arg-Arg-OH.CH3CO2H; L-Cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-seryl-L-alanyl-L-prolyl-L-arginyl-L-arginine acetate salt; L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-seryl-L-alanyl-L-prolyl-L-arginyl-L-arginine acetic acid. Grade: ≥95%. CAS No. 2803415-96-3. Molecular formula: C44H81N15O11S.C2H4O2. Mole weight: 1088.33.
P62-mediated mitophagy inducer
P62-mediated mitophagy inducer (PMI) is a P62-mediated mitophagy activator. P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809031-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115576.
P-725C is a prostaglandin synthetase inhibitor produced by Penicillum thomii. Synonyms: 6-Hydroxy-2-methyl-5-(1-oxopropyl)-2H-1,4-oxazine-3-carboxylic acid. CAS No. 87979-96-2. Molecular formula: C9H11NO5. Mole weight: 213.19.
P7C3. Group: Biochemicals. Grades: Purified. CAS No. 301353-96-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
P7C3-A20
P7C3-A20. Group: Biochemicals. Alternative Names: N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline. Grades: Highly Purified. CAS No. 1235481-90-9. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
P7C3-A20
P7C3-A20 is a derivative of P7C3 with potent proneurogenic and neuroprotective activity. P7C3-A20 exerts an antidepressant-like effect. P7C3-A20 can cross the blood-brain barrier and therefore has the potential for brain injury treatment[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1235481-90-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15978.
P9 is an antimicrobial peptide found in Cervus elaphus (New Zealand red deer), and has antibacterial activity. Grade: >98%.
p97 ATPase Activity Inhibitor, DBeQ
The p97 ATPase Activity Inhibitor, DBeQ controls the biological activity of p97 ATPase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
PA-1329-E1
PA-1329-E1 is a nucleoside antibiotic produced by Micromonospora sp. PA-1329. It exhibits activity against Candida albicans. Synonyms: Antibiotic PA-1329-E1. CAS No. 80860-79-3. Molecular formula: C15H23N7O5. Mole weight: 381.39.
PA (224-233), Influenza
PA (224-233), Influenza, a 10-aa peptide, is a fragment of polymerase 2 protein in influenza A virus. Synonyms: Ser-Ser-Leu-Glu-Asn-Phe-Arg-Ala-Tyr-Val; L-seryl-L-seryl-L-leucyl-L-alpha-glutamyl-L-asparagyl-L-phenylalanyl-L-arginyl-L-alanyl-L-tyrosyl-L-valine. Grade: ≥95%. CAS No. 271573-27-4. Molecular formula: C53H80N14O17. Mole weight: 1185.29.
PA-31088-II
PA-31088-II is a carbapenem antibiotic produced by Streptomyces tokunonensis PA-31088 and Str. argenteolus PA-39504. Molecular formula: C13H16N2O6S. Mole weight: 328.34.
PA-32413-I
PA-32413-I is a beta-lactam antibiotic produced by Streptomyces clavuigerus PA-32413. It is active against gram-positive and gram-negative bacteria. Synonyms: PA-32413 I; PA 32413 I. Molecular formula: C18H25N5O10S. Mole weight: 503.48.
PA452
PA452, retinoic X receptor ( RXR ) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 457657-34-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108522.
PA 452
PA 452. Group: Biochemicals. Grades: Purified. CAS No. 457657-34-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PA-46101 A
PA-46101 A is a macrolide antibiotic isolated from the culture broth of Streptomyces sp. PA-46101. It is active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria. Synonyms: PA 46101 A. CAS No. 130743-11-2. Molecular formula: C52H70O18. Mole weight: 983.1.
PA-46101 B
PA-46101 B is a macrolide antibiotic isolated from the culture broth of Streptomyces sp. PA-46101. It is active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria. Synonyms: PA 46101 B. CAS No. 130812-34-9. Molecular formula: C61H86O22. Mole weight: 1171.3.
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1 -, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC 50 of 2 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 878437-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133529.
PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I ( PAC1 ) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC 50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1436004-46-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129421.
Pa-AMP2
Pa-AMP2 is an antimicrobial peptide found in pokeweed seeds, Phytolacca americana, and has anti-gram-positive bacteria and fungal activity. Synonyms: Phytolacca americana antimicrobial peptide 2. Grade: >98%.
PAβN dihydrochloride
PAβN dihydrochloride is an efflux pump inhibitor and a substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: H-Phe-Arg-βNA.2HCl; Phe-Arg β-naphthylamide dihydrochloride. Grade: ≥ 99% (TLC). CAS No. 100929-99-5. Molecular formula: C25H32Cl2N6O2. Mole weight: 519.47.