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| Product | Description | |
|---|---|---|
| Paeciloquinone D | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2-Anthraceneacetic acid, 9,10-dihydro-1,3,6,8-tetrahydroxy-a-(2-hydroxyethyl)-9,10-dioxo-. CAS No. 162797-35-5. Molecular formula: C18H14O9. Mole weight: 374.30. |  |
| Paeciloquinone E | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2,5-Ethanoanthra[2,3-d]-1,3-dioxepin-7,12-dione, 4,5-dihydro-6,8,10-trihydroxy-2-methyl-, (1R,17R)-. CAS No. 162797-36-6. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Paeciloquinone F | It is produced by the strain of Paecilomyces carneus P-177. It can inhibit the epidermal growth factor receptor protein tyrosine kinase. Synonyms: 2,5-Epoxyanthra[2,3-b]oxepin-5(2H)-carboxylic acid, 3,4,7,12-tetrahydro-6,8,10-trihydroxy-2-methyl-7,12-dioxo-, (1S,17R)-. CAS No. 162797-37-7. Molecular formula: C20H14O9. Mole weight: 398.32. | |
| Paederia Foetida P.E. 10:1 | Paederia Foetida P.E. 10:1. |  CA, FL & NJ |
| Paederoside | Paederoside is a monoterpene S-methyl thiocarbonate isolated from Paederia pertomentosa. Paederoside shows a high anti-tumor promoting activity against the Epstein-Barr virus activation. Group: Inhibitors. CAS No. 20547-45-9. Molecular formula: C18H22O11S. Mole weight: 446.43. Appearance: Powder. Purity: 0.98. IUPACName: [(4S,7S,8S,11S)-2-oxo-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[5.3.1.04,11]undeca-1(10),5-dien-6-yl]methyl methylsulfanylformate. Canonical SMILES: CSC (=O)OCC1=C[C@H]2[C@H]3[C@@H]1[C@@H] (OC=C3C (=O)O2)O[C@H]4[C@@H] ([C@H] ([C@@H] ([C@H] (O4)CO)O)O)O. Density: 1.65±0.1 g/ml. Catalog: ACM20547459. |  |
| Paederoside | Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 20547-45-9. Pack Sizes: 10mg, 20mg. US Biological Life Sciences. |  Worldwide |
| Paederosidic acid | Paederosidic acid is isolated from P. scandens with anticancer and anti?inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis [1]. Uses: Scientific research. Group: Natural products. CAS No. 18842-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N6998. |  |
| Paederosidic acid | Paederosidic acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 18842-98-3. Pack Sizes: 10mg. Molecular Formula: C18H24O12S, Molecular Weight: 464.44. US Biological Life Sciences. | Worldwide |
| Paederosidic Acid Methyl Ester | Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 122413-01-8. Pack Sizes: 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| Paenicidin A | Paenicidin A is an antimicrobial peptide found in Paenibacillus polymyxa NRRL B-30509, and has antimicrobial activity. It is a highly cyclized lantibiotic, containing three lanthionines (between residues 3-7, 8-11, 19-24) and three methyllanthionine rings (between residues 16-20, 23-28, 30-36), three of which are interlocking. Synonyms: paeA. Grades: >98%. | |
| Paeonia Lactiflora Extract | Plant extract obtained from the peony (Paeonia Lactiflora root), a flower associated with well-being and rejuvenation. The active ingredient is peoniflorin. In vitro studies showed that it triggers mitophagy to optimize energy production, detoxify cells from ROS (reactive oxygen species), make them more resilient to damages and revitalize skin cells for an anti-aging effect. Peoniflorin together with trehalose have excellent detoxifying and anti-aging properties making the skin look rejuvenated and energized. Uses: Anti-aging preventive face and body care products, energizing & regenerating treatments. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 99-20-7 / 532-32-1 / 24634-61-5. Catalog: CI-SC-0949. | |
| Paeonia Suffruticosa Root Extract | Paeonia Suffruticosa Root Extract is an ingredient derived from the roots of the Peony plant, which is also known as tree peony or the mudan plant. This extract is commonly used in skincare and cosmetic products due to its purported anti-inflammatory, antioxidant, and skin brightening effects. The active compounds in Paeonia Suffruticosa Root Extract include paeoniflorin, catechin, and gallic acid, which are known for their anti-inflammatory effects. These compounds are believed to help reduce redness, swelling, and irritation in the skin. Additionally, the antioxidant properties of this extract are thought to protect the skin against free radical damage, which can lead to premature aging and skin damage. In addition to its anti-inflammatory and antioxidant properties, Paeonia Suffruticosa Root Extract is also believed to have skin brightening effects. It is said to inhibit the production of melanin, which can lead to hyperpigmentation and uneven skin tone. Uses: 1. anti-inflammatory: paeonia suffruticosa root extract has anti-inflammatory properties that help in reducing inflammation and swelling. 2. antioxidant: the extract is a rich source of antioxidants that protect the skin from free radical damage. 3. skin brightening: it can help improve the complexion and make the skin look brighter. 4. anti-aging: it has anti-aging properties that can help reduce. Group: Skin actives. CAS No. 223747-88-4. Appea | |
| Paeoniflorgenin | Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin [1]. Uses: Scientific research. Group: Natural products. CAS No. 697300-41-7. Pack Sizes: 1 mg. Product ID: HY-N7686. | |
| Paeoniflorin | Paeoniflorin is a heat shock protein -inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Peoniflorin. CAS No. 23180-57-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0293. | |
| Paeoniflorin | Paeoniflorin. Group: Biochemicals. Alternative Names: Peoniflorin. Grades: Plant Grade. CAS No. 23180-57-6. Pack Sizes: 20mg. Molecular Formula: C23H28O11, Molecular Weight: 480.461999999999. US Biological Life Sciences. | Worldwide |
| Paeoniflorin | 100mg Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks, Research Organics & Inorganics. Formula: C23H28O11. CAS No. 23180-57-6. Prepack ID 28377772-100mg. Molecular Weight 480.46. See USA prepack pricing. |  |
| Paeonol | Paeonol. Group: Biochemicals. Alternative Names: 2?-Hydroxy-4?-methoxyacetophenone; Peonol. Grades: Plant Grade. CAS No. 552-41-0. Pack Sizes: 20mg. Molecular Formula: C9H10O3, Molecular Weight: 166.174. US Biological Life Sciences. | Worldwide |
| Paeonol | Paeonol - Product ID: NST-10-30. Category: Phenylpropanoids. Alternative Names: 2'-Hydroxy-4'-methoxyacetophenone. Purity: 98%. Test method: HPLC. CAS No. 552-41-0. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: White powder. Molecular formula: C9H10O3. Mole weight: 166.17. Storage: +2 +8 °C. |  |
| Paeonol | Paeonol is an active extraction from the root of Paeonia suffruticosa , Paeonol inhibits MAO-A and MAO-B with IC 50 of 54.6 μM and 42.5 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 552-41-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0159. | |
| Paeonolide | Paeonolide. Group: Biochemicals. Alternative Names: Peonolide. Grades: Plant Grade. CAS No. 72520-92-4. Pack Sizes: 20mg. Molecular Formula: C20H28O12, Molecular Weight: 460.428999999999. US Biological Life Sciences. | Worldwide |
| Paeonoside | Paeonoside is an intriguing natural compound derived from the roots of Paeonia lactiflora, aiding in studying inflammatory ailments, notably rheumatoid arthritand ulcerative colitis. with inherent anti-inflammatory attributes. Synonyms: 2-Acetyl-5-methoxyphenyl β-D-Glucopyranoside. Grades: > 95%. CAS No. 20309-70-0. Molecular formula: C15H20O8. Mole weight: 328.32. | |
| PAF | PAF is an antimicrobial peptide found in Penicillium chrysogenum (Penicillium notatum), and has antifungal activity. Synonyms: Penicillium Antifungal protein (PAF). Grades: >98%. | |
| PAF26 | PAF26 is a cell penetration peptide found in Screened from Synthetic Combinatorial Peptide Library. It has antifungal and antibacterial activity. Synonyms: Ac-Arg-Lys-Lys-Trp-Phe-Trp-NH2; N-acetyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-phenylalanyl-L-tryptophanamide; L-Tryptophanamide, N2-acetyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-phenylalanyl-. Grades: ≥95%. Molecular formula: C51H70N14O7. Mole weight: 991.19. | |
| PAFAH1b2/3-IN-P11 | P11 is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH) 1b2 and 1b3. At 10 μM, it has been shown to impair Neuro2a and PC3 tumor cell survival. Synonyms: (2S,6S)-6-(4-Tert-butylphenyl)-2-(4-methylphenyl)-1-(4-methylphenyl)sulfonyl-3,6-dihydro-2H-pyridine-5-carboxylic acid. Grades: ≥98%. CAS No. 942285-55-4. Molecular formula: C30H33NO4S. Mole weight: 503.7. | |
| PAF-AN-1 | PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist. Synonyms: SDZ 64-412; SDZ-64-412; SDZ64-412. 5-[4-[2-(3,4,5-trimethoxyphenyl)ethyl]phenyl]-2,3-dihydroimidazo[2,1-a]isoquinoline; 5-(4'-(3,4,5-trimethoxyphenylethyl)phenyl)-2,3-dihydroimidazo(2,1-a)isoquinoline; SDZ 64-412; SDZ-64-412. CAS No. 115621-84-6. Molecular formula: C28H28N2O3. Mole weight: 440.53. | |
| PAF (C16) | PAF (C16). Group: Biochemicals. Grades: Purified. CAS No. 74389-68-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PAF (C16) | PAF (C16) is an endogenous platelet-activating factor (PAF). It can induce increased vascular permeability. Synonyms: C16-02:0 PC; PC(16:0e/2:0); C16 PAF; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; PAF C-16. Grades: 98%. CAS No. 74389-68-7. Molecular formula: C26H54NO7P. Mole weight: 523.68. | |
| PAF C-16 Carboxylic Acid | Phospholipids. Alternative Names: (R)-7-(acetyloxy)-24-carboxy-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphatetracosan-1-aminium, inner salt, 4-oxide; CPAGP; Platelet-activating Factor C-16 Carboxylic Acid. CAS No. 129879-41-0. Molecular formula: C26H52NO9P. Mole weight: 553.7. Purity: ≥95%. IUPACName: [(2R)-2-acetyloxy-3-(15-carboxypentadecoxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate. Canonical SMILES: CC (=O)O[C@H] (COCCCCCCCCCCCCCCCC (=O)O)COP (=O) ([O-])OCC[N+] (C) (C)C. Catalog: ACM129879410. | |
| Pafolacianine | Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775?nm and emits at 794 to 796?nm [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: OTL 38. CAS No. 1628423-76-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139579. | |
| Pafuramidine | Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DB289. CAS No. 186953-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14932. | |
| Pafuramidine | DB289 (pafuramidine maleate; 2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) is a prodrug of DB75 (furamidine dihydrochloride; 2,5-bis(4-guanylphenyl)furan dihydrochloride), an aromatic dication related to pentamidine that has demonstrated good efficacy against African trypanosomiasis, Pneumocystis carinii pneumonia, and malaria, but lacks adequate oral availability. Synonyms: DB289; DB-289; DB 289; Pafuramidine. Grades: >98%. CAS No. 186953-56-0. Molecular formula: C20H20N4O3. Mole weight: 364.4. | |
| Pagibaximab | Pagibaximab is a chimeric IgG1 antibody recognizing the surface component lipoteichoic acid of S. aureus and S. epidermidis. Pagibaximab can be used to prevent staphylococcal sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BSYX-A 110; Anti-S. Epidermidis LTA Recombinant Antibody. CAS No. 595566-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99309. | |
| Pagoclone | Pagoclone, an active (+)-enantiomer of the racemate RP 59037, is a ubtype selective partial agonist at GABAA receptor and used for the treatment of panic and anxiety disorders. Synonyms: CI-1043; IP-456; RP-62955; RP-59037; CI1043; IP456; RP62955; RP59037; Bextra. CAS No. 133737-32-3. Molecular formula: C23H22ClN3O2. Mole weight: 407.89. | |
| Pagoclone | Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-RP-59037; IP-456; RP-62955. CAS No. 133737-32-3. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-101665. | |
| Paint & Coatings |  | |
| Paired box protein Pax-5 (311-319) | Paired box protein Pax-5 (311-319) is a bioactive peptide of Paired box protein Pax-5. Paired box protein Pax-5 is a transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Synonyms: B-cell-specific transcription factor (311-319). | |
| PalA I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and 95% of these can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GG↑CGCGCC CCGCGC↓GG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E. coli strain , that carries the cloned gene from Pseudomanas alcaligenes BS17. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1143RE. |  |
| Palamethasone Acetate | Palamethasone Acetate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1597-82-6. Molecular Formula: C24H31FO6. Mole Weight: 434.5. Catalog: APB1597826. |  |
| Palatine fast yellow bln | Heterocyclic Organic Compound. Alternative Names: PALATINE FAST YELLOW BLN;ACID YELLOW 54;CHROMOLAN YELLOW;CI 19010;PALATINE FAST YELLOW BLN DYE CONTENT: APPROX. 70%;dyecontent:approx.70%;C.I. Acid Yellow 54;PALATINE FAST YELLOW BLN, PURE. CAS No. 10127-05-6. Molecular formula: C18H13N4Na3O9S2. Mole weight: 607.427. Catalog: ACM10127056. | |
| Palatinitol | 100mg Pack Size. Group: Building Blocks, Carbohydrates. Formula: C12H24O11. CAS No. 64519-82-0. Prepack ID 28517137-100mg. Molecular Weight 344.31. See USA prepack pricing. | |
| Palatinitol | 1g Pack Size. Group: Building Blocks, Carbohydrates. Formula: C12H24O11. CAS No. 64519-82-0. Prepack ID 28517137-1g. Molecular Weight 344.31. See USA prepack pricing. | |
| Palatinose | 25g Pack Size. Group: Carbohydrates, Sugars. Formula: C12H22O11. CAS No. 13718-94-0. Prepack ID 17108147-25g. Molecular Weight 342.3. See USA prepack pricing. | |
| Palatinose Hydrate | Isomaltulose is another sugar substitute, and non-cariogenic substance. Synonyms: D-Fructose, 6-O-α-D-glucopyranosyl-, hydrate; 6-O-α-D-Glucopyranosyl-D-Fructose Hydrate; Isomaltulose Hydrate. Grades: ≥99%. CAS No. 343336-76-5. Molecular formula: C12H22O11.xH2O. Mole weight: 342.30 (anhydrous basis). | |
| Palatinose Monohydrate | Palatinose Hydrate, a natural occurring disaccharide composed of α-1,6-linked glucose and fructose, can be used as an alternative sugar. Because it is absorbed more slowly than sucrose, it can be used as a sweetener for diabetic patients. Synonyms: 6-O-α-D-Glucopyranosyl-D-fructose Monohydrate; Galen IQ Hydrate; Palatinose Monohydrate; Isomaltulose Monohydrate; Palatinose IC Monohydrate; Palatinose ICP Monohydrate. CAS No. 58024-13-8. Molecular formula: C12H22O11 H2O. Mole weight: 342.30. | |
| Palazestrant | Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC 50 value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC 50 value of 1.4-1.6 nM. Palazestrant can inhibit ER + /HER2 + cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OP-1250. CAS No. 2092925-89-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148789. | |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma. Group: Inhibitors. Alternative Names: Palbociclib; 571190-30-2; PD0332991; Ibrance; PD-0332991; PD 0332991;UNII-G9ZF61LE7G;Palbociclib free base;Palbociclib-d8;6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;PD-332991;571190-30-2 (free base); MFCD11840850; 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2, 3-D]PYRIMIDIN-7(8H)-ONE; 6-Acetyl-8-cyclop. CAS No. 571190-30-2. Molecular formula: C24H29N7O2. Mole weight: 447.5g/mol. Purity: 0.9994. IUPACName: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one. Canonical SMILES: CC1=C (C (=O)N (C2=NC (=NC=C12)NC3=NC=C (C=C3)N4CCNCC4)C5CCCC5)C (=O)C. Catalog: ACM571190302. | |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991. CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767. | |
| Palbociclib | Palbociclib Inhibitor. Uses: Scientific use. Product Category: T1785. CAS No. 571190-30-2. |  |
| Palbociclib-D8 | Palbociclib-D8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1628752-83-9. Molecular Formula: C24H21D8N7O2. Mole Weight: 455.59. Catalog: APB1628752839. | |
| Palbociclib, Free Base Salt, 99+% | PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells. Group: Biochemicals. Alternative Names: 6-acetyl-8-cyclopentyl-5-methyl-2- [ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d]pyrimidin-7 (8H) -one 2-hydroxy-ethanesulfonic acid (1:1); PD0332991; Palbociclib; isethionate. Grades: Highly Purified. CAS No. 571190-30-2. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Palbociclib HCl | Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein phosphorylation; inhibition of Rb phosphorylation prevents Rb-positive tumor cells from entering the S phase of the cell cycle (arrest in the G1 phase), resulting in suppression of DNA replication and decreased tumor cell proliferation. PD 0332991 is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) (IC50=0.011 μmol/L) and Cdk6 (IC50=0.016 μmol/L), having no activity against a panel of 36 additional protein kinases. Synonyms: PD 0332991; PD 332991; PD0332991; PD-0332991; Palbociclib hydrochloride. Grades: >98%. CAS No. 827022-32-2. Molecular formula: C24H29N7O2.HCl. Mole weight: 483.99. | |
| Palbociclib hydrochloride | Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-0332991 hydrochloride. CAS No. 571189-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767C. | |
| Palbociclib Impurity 002 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C14H21BrN4. Mole weight: 325.25. | |
| Palbociclib Impurity 022 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; 1779124-68-3; tert-Butyl4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; SCHEMBL17550837; CS-0448403; EN300-7455913. Grades: 95%. CAS No. 1779124-68-3. Molecular formula: C14H20N4O4. Mole weight: 308.33. | |
| Palbociclib Impurity 025 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: N-Formyl Palbociclib; Palbociclib Impurity F; Palbociclib N-Aldehyde; Palbociclib N-Formyl Impurity. Grades: 95%. CAS No. 2174002-16-3. Molecular formula: C25H29N7O3. Mole weight: 475.54. | |
| Palbociclib Impurity 026 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C28H37N7O2. Mole weight: 503.64. | |
| Palbociclib Impurity 027 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C27H35N7O2. Mole weight: 489.61. | |
| Palbociclib Impurity 028 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C18H24N4O. Mole weight: 312.41. | |
| Palbociclib Impurity 029 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(2-nitropyridin-3-yl)piperazine; 1566082-34-5; GS0805; EN300-2138375. Grades: 95%. CAS No. 1566082-34-5. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 030 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(4-nitropyridin-3-yl)piperazine; GS0814; 1211541-02-4. Grades: 95%. CAS No. 1211541-02-4. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 1 | Palbociclib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 571190-22-2. Molecular Formula: C22H27N7O. Mole Weight: 405.51. Catalog: APB571190222. | |
| Palbociclib Impurity 10 | Palbociclib Impurity 10 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-Piperazinecarboxylic acid, 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis-, 1,1'-bis(1,1-dimethylethyl) ester; 1,1'-Bis(1,1-dimethylethyl) 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis[1-piperazinecarboxylate]; Bis(2-methyl-2-propanyl) 4,4'-[(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]di(1-piperazinecarboxylate). Grades: 95%. CAS No. 2206135-30-8. Molecular formula: C41H55N11O5. Mole weight: 781.94. | |
| Palbociclib Impurity 11 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C33H45N7O4. Mole weight: 603.77. | |
| Palbociclib Impurity 11 | Palbociclib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 866084-31-3. Molecular Formula: C33H45N7O4. Mole Weight: 603.77. Catalog: APB866084313. | |
| Palbociclib Impurity 12 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: tert-butyl 4-(6-((2-chloro-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C27H34ClN7O3. Mole weight: 540.07. | |
| Palbociclib Impurity 13 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54. | |
| Palbociclib Impurity 13 TriHCl | Palbociclib Impurity 13 TriHCl is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one, hydrochloride (1:3). Molecular formula: C24H32N7O2Cl3. Mole weight: 583.92. | |
| Palbociclib Impurity 14 | Palbociclib Impurity 14 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Butenoic acid, 2-(2,2-dimethoxyethyl)-, methyl ester; methyl (Z)-2-(2,2-dimethoxyethyl)but-2-enoate; 2-Butenoicacid,2-(2,2-dimethoxyethyl)-,methylester. CAS No. 51534-87-3. Molecular formula: C9H16O4. Mole weight: 188.22. | |
| Palbociclib Impurity 14 | Palbociclib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 51534-87-3. Molecular Formula: C9H16O4. Mole Weight: 188.22. Catalog: APB51534873. | |
| Palbociclib Impurity 15 | Palbociclib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 51534-82-8. Molecular Formula: C9H16O5. Mole Weight: 204.22. Catalog: APB51534828. | |
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