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Palbociclib Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-(2-aminopyridin-3-yl)piperazine-1-carboxylate. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35. Catalog: APB1023594491.
Palbociclib Impurity 37
Palbociclib Impurity 37 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2144748-14-9. Molecular formula: C14H18N6. Mole weight: 270.34.
Palbociclib Impurity 38
Palbociclib Impurity 38 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-(1-Butoxyethenyl)-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2270982-31-3. Molecular formula: C28H37N7O2. Mole weight: 503.65.
Palbociclib Impurity 4
An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: Pyrido[2,?3-d]?pyrimidin-7(8H)?-one, 8-cyclopentyl-6-(1-hydroxyethyl)?-5-methyl-2-[[5-(1-piperazinyl)?-2-pyridinyl]?amino]?-. Grades: > 95%. CAS No. 1376615-91-6. Molecular formula: C24H31N7O2. Mole weight: 449.56.
Palbociclib Impurity 40
Palbociclib Impurity 40 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H35N3O. Mole weight: 393.58.
Palbociclib Impurity 41
Palbociclib Impurity 41 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C19H24BrN3O. Mole weight: 390.33.
Palbociclib Impurity 42
Palbociclib Impurity 42 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one. Grades: 98%. CAS No. 1016636-76-2. Molecular formula: C13H13BrClN3O. Mole weight: 342.62.
Palbociclib Impurity 46
Palbociclib Impurity 46 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 8-Cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione. CAS No. 2375089-01-1. Molecular formula: C13H15N3O2. Mole weight: 245.28.
Palbociclib Impurity 47
Palbociclib Impurity 47 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-Bromo-2-chloropyrimidin-4(3H)-one; 5-Bromo-2-chloro-4(3H)-pyrimidinone; 5-Bromo-2-chloropyrimidin-4-ol. Grades: 95%. CAS No. 844843-37-4. Molecular formula: C4H2BrClN2O. Mole weight: 209.43.
Palbociclib Impurity 48
Palbociclib Impurity 48 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C40H42Br2N12O2. Mole weight: 882.67.
Palbociclib Impurity 49
Palbociclib Impurity 49 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-γ-oxo-1-piperazinebutanoic acid. CAS No. 1974279-21-4. Molecular formula: C28H33N7O5. Mole weight: 547.62.
Palbociclib Impurity 5
An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide. Grades: > 95%. Molecular formula: C24H30N7O3. Mole weight: 464.55.
Palbociclib Impurity 50
Palbociclib Impurity 50 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H29N7O4. Mole weight: 491.55.
Palbociclib Impurity 51
Palbociclib Impurity 51 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-(4-butylpiperazin-1-yl)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Molecular formula: C28H37N7O2. Mole weight: 503.65.
Palbociclib Impurity 53
Palbociclib Impurity 53 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-bromo-2-chloro-N-cyclopentyl-4-pyrimidinamine; 5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine. Grades: >95%. CAS No. 733039-20-8. Molecular formula: C9H11BrClN3. Mole weight: 276.56.
Palbociclib Impurity 54
Palbociclib Impurity 54 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Chloro-N-cyclopentyl-4-pyrimidinamine; (2-Chloropyrimidin-4-yl)(cyclopentyl)amine. CAS No. 868591-58-6. Molecular formula: C9H12ClN3. Mole weight: 197.67.
Palbociclib Impurity 55
Palbociclib Impurity 55 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-Bromo-N,N-dicyclopentyl-2,4-pyrimidinediamine. CAS No. 2444702-87-6. Molecular formula: C14H21BrN4. Mole weight: 325.25.
Palbociclib Impurity 56
Palbociclib Impurity 56 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-(4-acetylpiperazin-1-yl)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 1974279-20-3. Molecular formula: C26H31N7O3. Mole weight: 489.58.
Palbociclib Impurity 57
Palbociclib Impurity 57 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H27N7O3. Mole weight: 461.53.
Palbociclib Impurity 58
Palbociclib Impurity 58 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-aminopyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2363172-64-7. Molecular formula: C20H22N6O2. Mole weight: 378.44.
Palbociclib Impurity 59
Palbociclib Impurity 59 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H25N7O4. Mole weight: 475.51.
Palbociclib Impurity 6
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide. Grades: > 95%. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Impurity 6
Palbociclib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153747-97-8. Molecular formula: C14H20BrN3O2. Mole weight: 342.23. Catalog: APB153747978.
Palbociclib Impurity 62
Palbociclib Impurity 62 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H35N7O8. Mole weight: 621.65.
Palbociclib Impurity 63
Palbociclib Impurity 63 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one. Grades: 97%. CAS No. 1013916-37-4. Molecular formula: C13H14ClN3O. Mole weight: 263.73.
Palbociclib Impurity 64
Palbociclib Impurity 64 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H31N7O3. Mole weight: 477.57.
Palbociclib Impurity 65
Palbociclib Impurity 65 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Impurity 66
Palbociclib Impurity 66 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H35N7O8. Mole weight: 621.65.
Palbociclib Impurity 67
Palbociclib Impurity 67 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2242625-36-9. Molecular formula: C13H16ClN3O2. Mole weight: 281.74.
Palbociclib Impurity 69
Palbociclib Impurity 69 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 1023594-50-4. Molecular formula: C14H22N4O2. Mole weight: 278.36.
Palbociclib Impurity 7
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[6-[(1E)?-2-butoxyethenyl]?-8-cyclopentyl-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-35-5. Molecular formula: C33H45N7O4. Mole weight: 603.77.
Palbociclib Impurity 70
Palbociclib Impurity 70 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C14H22N4O3. Mole weight: 294.36.
Palbociclib Impurity 71
Palbociclib Impurity 71 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C28H33N7O7. Mole weight: 579.61.
Palbociclib Impurity 74
Palbociclib Impurity 74 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Di-tert-butyl 4,4'-(diazene-1,2-diylbis(pyridine-6,3-diyl))(E)-bis(piperazine-1-carboxylate). CAS No. 2399424-46-3. Molecular formula: C28H40N8O4. Mole weight: 552.68.
Palbociclib Impurity 75
Palbociclib Impurity 75 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C28H42N8O4. Mole weight: 554.7.
Palbociclib Impurity 75
Palbociclib Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,6-dibromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 1415560-29-0. Molecular formula: C13H13Br2N3O. Mole weight: 387.07. Catalog: APB1415560290.
Palbociclib Impurity 77
Palbociclib Impurity 77 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C13H12BrCl2N3O. Mole weight: 377.06.
Palbociclib Impurity 78
Palbociclib Impurity 78 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C14H21N5O4. Mole weight: 323.35.
Palbociclib Impurity 8
An impurity of Palbociclib which which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[8-cyclopentyl-6-(2-ethoxyethenyl)?-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-31-1. Molecular formula: C31H41N7O4. Mole weight: 575.72.
Palbociclib Impurity 80
Palbociclib Impurity 80 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-8-cyclohexyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one. CAS No. 2624141-94-0. Molecular formula: C25H31N7O2. Mole weight: 461.57.
Palbociclib Impurity 81
Palbociclib Impurity 81 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-(piperazin-1-yl)pyridin-2-amine. CAS No. 1082876-26-3. Molecular formula: C9H14N4. Mole weight: 178.24.
Palbociclib Impurity 83
Palbociclib Impurity 83 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Impurity 84
Palbociclib Impurity 84 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 3-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol. CAS No. 1374639-76-5. Molecular formula: C12H14ClN3O. Mole weight: 251.71.
Palbociclib Impurity 9
An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: 2-(8-cyclopentyl-5-methyl-7-oxo-2-((4-(piperazin-1-yl)phenyl)amino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)acetaldehyde. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54.
Palbociclib Impurity 9 DiHCl
Palbociclib Impurity 9 DiHCl is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-(8-cyclopentyl-5-methyl-7-oxo-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)acetaldehyde, hydrochloride (1:2). Molecular formula: C24H31N7O2Cl2. Mole weight: 520.46.
Palbociclib Impurity F
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: 95%. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35.
Palbociclib Impurity FLT
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C37H51N7O11. Mole weight: 769.85.
Palbociclib Impurity I
Palbociclib Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1016636-76-2. Molecular formula: C13H13BrClN3O. Mole weight: 342.62. Catalog: APB1016636762.
Palbociclib Impurity N
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C27H35N7O2. Mole weight: 489.62.
Palbociclib Impurity O
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C28H37N7O2. Mole weight: 503.65.
Palbociclib Impurity P
Palbociclib Impurity P. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1082876-26-3. Molecular formula: C9H14N4. Mole weight: 178.24. Catalog: APB1082876263.
Palbociclib Impurity P
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C41H54BrN11O5. Mole weight: 860.86.
Palbociclib Impurity V
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C28H40N8O5. Mole weight: 568.68.
Palbociclib isethionate
Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 isethionate. CAS No. 827022-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0065.
Palbociclib Isethionate
Palbociclib is a potent Cdk4/6 inhibitor. Synonyms: PD 0332991 Isethionate; PD0332991 Isethionate; PD-0332991 Isethionate; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one isethionate. Grades: >98%. CAS No. 827022-33-3. Molecular formula: C26H35N7O6S. Mole weight: 573.66.
Palbociclib Isethionate
Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Palbociclib Isethionate;827022-33-3;PD0332991 Isethionate;PD 0332991 isethionate;UNII-W1NYL2IRDR;Palbociclib (PD0332991) Isethionate;W1NYL2IRDR;Palbociclib (isethionate);827022-33-3 (isethionate);6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethanesulfonate;Palbociclib Isethionate [USAN];PD 0332991-0054;PF-00080665-73;6-acetyl-8-. Product Category: Inhibitors. CAS No. 827022-33-3. Molecular formula: C26H35N7O6S. Mole weight: 573.7g/mol. Purity: 0.9999. IUPACName: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one;2-hydroxyethanesulfonic acid. Canonical SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O. Product ID: ACM827022333. Alfa Chemistry ISO 9001:2015 Certified.
Palbociclib Lactose adduct 1
Palbociclib Lactose adduct 1 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib N-Lactose. Molecular formula: C36H49N7O12. Mole weight: 771.83.
Palbociclib Lactose adduct 2
Palbociclib Lactose adduct 2 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(4-((3S,4R,5R)-3,5,6-trihydroxy-2-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Rearranged Lactose Adduct. Molecular formula: C36H49N7O12. Mole weight: 771.83.
Palbociclib monohydrochloride
Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 monohydrochloride. CAS No. 827022-32-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50767A.
Palbociclib N-b-D-Glucuronide Sodium Salt
Palbociclib N-b-D-Glucuronide Sodium Salt is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H36N7NaO8. Mole weight: 645.64.
Palbociclib N-Ethyl
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-acetyl-8-cyclopentyl-2-((5-(4-ethylpiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib impurity 33. Grades: ≥95%. CAS No. 1974279-40-7. Molecular formula: C26H33N7O2. Mole weight: 475.59.
Palbociclib N-Glucuronide
A salt of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: (2R,4R,6S)-6-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C30H37N7O8. Mole weight: 623.66.
Palbociclib N-oxide
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide. Grades: ≥95%. CAS No. 2174002-29-8. Molecular formula: C24H29N7O3. Mole weight: 463.53.
Palbociclib Pyridine N-Oxide
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. CAS No. 2098673-40-4. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib (Standard)
Palbociclib (Standard) is the analytical standard of Palbociclib. This product is intended for research and analytical applications. Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 (Standard). CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50767R.
Palbociclib Sulfamic Acid
Palbociclib Sulfamic Acid is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-sulfonic acid. Grades: > 95%. CAS No. 2204863-10-3. Molecular formula: C24H29N7O5S. Mole weight: 527.61.
PALDA
PALDA. Group: Biochemicals. Grades: Purified. CAS No. 136181-87-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PALDA
PALDA is an endogenous lipid and it can potentiate effects of endovanilloids at TRPV1 receptors. Synonyms: N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide. Grades: ≥98% by HPLC. CAS No. 136181-87-8. Molecular formula: C24H41NO3. Mole weight: 391.59.
Paldimycin
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- (2-methylpropanoyloxy) ethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- [ (2S) -2-methylbutanoyl] oxyethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid. CAS No. 102426-96-0. Molecular formula: C87H126N8O46S6. Mole weight: 2212.34.
Paldimycin A
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1-alpha; L-Cysteine, N-acetyl-, [2-[[2- (acetylamino)-2-carboxyethyl]thio]-1-carboxypropyl]carbamodithioate (ester), 4'-ester with 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[1-(2-methyl-1-oxobutoxy)ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4''-C-((2S)-2-methylbutyrate), S-ester with N-acetyl-L-cysteine. CAS No. 101411-70-5. Molecular formula: C44H64N4O23S3. Mole weight: 1113.18.