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Palbociclib Impurity 63 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one. Grades: 97%. CAS No. 1013916-37-4. Molecular formula: C13H14ClN3O. Mole weight: 263.73.
Palbociclib Impurity 64
Palbociclib Impurity 64 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H31N7O3. Mole weight: 477.57.
Palbociclib Impurity 65
Palbociclib Impurity 65 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Impurity 66
Palbociclib Impurity 66 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H35N7O8. Mole weight: 621.65.
Palbociclib Impurity 67
Palbociclib Impurity 67 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2242625-36-9. Molecular formula: C13H16ClN3O2. Mole weight: 281.74.
Palbociclib Impurity 69
Palbociclib Impurity 69 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 1023594-50-4. Molecular formula: C14H22N4O2. Mole weight: 278.36.
Palbociclib Impurity 7
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[6-[(1E)?-2-butoxyethenyl]?-8-cyclopentyl-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-35-5. Molecular formula: C33H45N7O4. Mole weight: 603.77.
Palbociclib Impurity 70
Palbociclib Impurity 70 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C14H22N4O3. Mole weight: 294.36.
Palbociclib Impurity 71
Palbociclib Impurity 71 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C28H33N7O7. Mole weight: 579.61.
Palbociclib Impurity 74
Palbociclib Impurity 74 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Di-tert-butyl 4,4'-(diazene-1,2-diylbis(pyridine-6,3-diyl))(E)-bis(piperazine-1-carboxylate). CAS No. 2399424-46-3. Molecular formula: C28H40N8O4. Mole weight: 552.68.
Palbociclib Impurity 75
Palbociclib Impurity 75 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C28H42N8O4. Mole weight: 554.7.
Palbociclib Impurity 75
Palbociclib Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,6-dibromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 1415560-29-0. Molecular Formula: C13H13Br2N3O. Mole Weight: 387.07. Catalog: APB1415560290.
Palbociclib Impurity 77
Palbociclib Impurity 77 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C13H12BrCl2N3O. Mole weight: 377.06.
Palbociclib Impurity 78
Palbociclib Impurity 78 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C14H21N5O4. Mole weight: 323.35.
Palbociclib Impurity 8
Palbociclib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 827022-31-1. Molecular Formula: C31H41N7O4. Mole Weight: 575.71. Catalog: APB827022311.
Palbociclib Impurity 8
An impurity of Palbociclib which which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[8-cyclopentyl-6-(2-ethoxyethenyl)?-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-31-1. Molecular formula: C31H41N7O4. Mole weight: 575.72.
Palbociclib Impurity 80
Palbociclib Impurity 80 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-8-cyclohexyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one. CAS No. 2624141-94-0. Molecular formula: C25H31N7O2. Mole weight: 461.57.
Palbociclib Impurity 81
Palbociclib Impurity 81 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-(piperazin-1-yl)pyridin-2-amine. CAS No. 1082876-26-3. Molecular formula: C9H14N4. Mole weight: 178.24.
Palbociclib Impurity 83
Palbociclib Impurity 83 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Impurity 84
Palbociclib Impurity 84 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 3-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol. CAS No. 1374639-76-5. Molecular formula: C12H14ClN3O. Mole weight: 251.71.
Palbociclib Impurity 9
An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: 2-(8-cyclopentyl-5-methyl-7-oxo-2-((4-(piperazin-1-yl)phenyl)amino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)acetaldehyde. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54.
Palbociclib Impurity 9
Palbociclib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204368-66-9. Molecular Formula: C24H29N7O2. Mole Weight: 447.54. Catalog: APB2204368669.
Palbociclib Impurity 9 DiHCl
Palbociclib Impurity 9 DiHCl is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-(8-cyclopentyl-5-methyl-7-oxo-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)acetaldehyde, hydrochloride (1:2). Molecular formula: C24H31N7O2Cl2. Mole weight: 520.46.
Palbociclib Impurity A
Palbociclib Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 39856-50-3. Molecular Formula: C5H3BrN2O2. Mole Weight: 203. Catalog: APB39856503.
Palbociclib Impurity B
Palbociclib Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204863-06-7. Molecular Formula: C24H29N7O. Mole Weight: 431.54. Catalog: APB2204863067.
Palbociclib Impurity C
Palbociclib Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1651214-74-2. Molecular Formula: C29H37N7O4. Mole Weight: 547.66. Catalog: APB1651214742.
Palbociclib Impurity C HCl
Palbociclib Impurity C HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1883672-48-7. Molecular Formula: C29H38ClN7O4. Mole Weight: 584.12. Catalog: APB1883672487.
Palbociclib Impurity D
Palbociclib Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 850918-83-1. Molecular Formula: C22H27BrClN7O. Mole Weight: 520.86. Catalog: APB850918831.
Palbociclib Impurity E
Palbociclib Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1779124-68-3. Molecular Formula: C14H20N4O4. Mole Weight: 308.34. Catalog: APB1779124683.
Palbociclib Impurity F
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: 95%. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35.
Palbociclib Impurity F
Palbociclib Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2174002-29-8. Molecular Formula: C24H29N7O3. Mole Weight: 463.54. Catalog: APB2174002298.
Palbociclib Impurity FLT
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C37H51N7O11. Mole weight: 769.85.
Palbociclib Impurity G
Palbociclib Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2377610-25-6. Molecular Formula: C11H21BF3NO4. Mole Weight: 299.1. Catalog: APB2377610256.
Palbociclib Impurity I
Palbociclib Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1016636-76-2. Molecular Formula: C13H13BrClN3O. Mole Weight: 342.62. Catalog: APB1016636762.
Palbociclib Impurity J
Palbociclib Impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1922954-32-2. Molecular Formula: C13H14BrN3O2. Mole Weight: 324.18. Catalog: APB1922954322.
Palbociclib Impurity K
Palbociclib Impurity K. Uses: For analytical and research use. Group: Impurity standards. CAS No. 571188-59-5. Molecular Formula: C14H22N4O2. Mole Weight: 278.36. Catalog: APB571188595.
Palbociclib Impurity M
Palbociclib Impurity M. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1376615-91-6. Molecular Formula: C24H31N7O2. Mole Weight: 449.56. Catalog: APB1376615916.
Palbociclib Impurity N
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C27H35N7O2. Mole weight: 489.62.
Palbociclib Impurity O
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C28H37N7O2. Mole weight: 503.65.
Palbociclib Impurity P
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C41H54BrN11O5. Mole weight: 860.86.
Palbociclib Impurity P
Palbociclib Impurity P. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1082876-26-3. Molecular Formula: C9H14N4. Mole Weight: 178.24. Catalog: APB1082876263.
Palbociclib Impurity Q
Palbociclib Impurity Q. Uses: For analytical and research use. Group: Impurity standards. CAS No. 827022-35-5. Molecular Formula: C33H45N7O4. Mole Weight: 603.77. Catalog: APB827022355.
Palbociclib Impurity R
Palbociclib Impurity R. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24N4O. Mole Weight: 312.42. Catalog: APB09495.
Palbociclib Impurity T
Palbociclib Impurity T. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2324831-15-2. Molecular Formula: C13H12Br2ClN3O. Mole Weight: 421.52. Catalog: APB2324831152.
Palbociclib Impurity U
Palbociclib Impurity U. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2270982-31-3. Molecular Formula: C28H37N7O2. Mole Weight: 503.65. Catalog: APB2270982313.
Palbociclib Impurity V
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: ≥95%. Molecular formula: C28H40N8O5. Mole weight: 568.68.
Palbociclib Impurity X
Palbociclib Impurity X. Uses: For analytical and research use. Group: Impurity standards. CAS No. 571189-65-6. Molecular Formula: C27H35N7O3. Mole Weight: 505.62. Catalog: APB571189656.
Palbociclib Impurity Y
Palbociclib Impurity Y. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2174002-16-3. Molecular Formula: C25H29N7O3. Mole Weight: 475.55. Catalog: APB2174002163.
Palbociclib isethionate
Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 isethionate. CAS No. 827022-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0065.
Palbociclib Isethionate
Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma. Group: Inhibitors. Alternative Names: Palbociclib Isethionate;827022-33-3;PD0332991 Isethionate;PD 0332991 isethionate;UNII-W1NYL2IRDR;Palbociclib (PD0332991) Isethionate;W1NYL2IRDR;Palbociclib (isethionate);827022-33-3 (isethionate);6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethanesulfonate;Palbociclib Isethionate [USAN];PD 0332991-0054;PF-00080665-73;6-acetyl-8-. CAS No. 827022-33-3. Molecular formula: C26H35N7O6S. Mole weight: 573.7g/mol. Purity: 0.9999. IUPACName: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one;2-hydroxyethanesulfonic acid. Canonical SMILES: CC1=C (C (=O)N (C2=NC (=NC=C12)NC3=NC=C (C=C3)N4CCNCC4)C5CCCC5)C (=O)C. C (CS (=O) (=O)O)O. Catalog: ACM827022333.
Palbociclib Isethionate
Palbociclib is a potent Cdk4/6 inhibitor. Synonyms: PD 0332991 Isethionate; PD0332991 Isethionate; PD-0332991 Isethionate; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one isethionate. Grades: >98%. CAS No. 827022-33-3. Molecular formula: C26H35N7O6S. Mole weight: 573.66.
Palbociclib Lactose adduct 1
Palbociclib Lactose adduct 1 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib N-Lactose. Molecular formula: C36H49N7O12. Mole weight: 771.83.
Palbociclib Lactose adduct 1
Palbociclib Lactose adduct 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-acetyl-8-cyclopentyl-2-((5-(4-((3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)piperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Molecular Formula: C36H49N7O12. Mole Weight: 771.81. Catalog: APB01956.
Palbociclib Lactose adduct 2
Palbociclib Lactose adduct 2 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(4-((3S,4R,5R)-3,5,6-trihydroxy-2-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Rearranged Lactose Adduct. Molecular formula: C36H49N7O12. Mole weight: 771.83.
Palbociclib N-b-D-Glucuronide Sodium Salt
Palbociclib N-b-D-Glucuronide Sodium Salt is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H36N7NaO8. Mole weight: 645.64.
Palbociclib N-Ethyl
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-acetyl-8-cyclopentyl-2-((5-(4-ethylpiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib impurity 33. Grades: ≥95%. CAS No. 1974279-40-7. Molecular formula: C26H33N7O2. Mole weight: 475.59.
Palbociclib N-Glucuronide
A salt of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: (2R,4R,6S)-6-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C30H37N7O8. Mole weight: 623.66.
Palbociclib N-oxide
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide. Grades: ≥95%. CAS No. 2174002-29-8. Molecular formula: C24H29N7O3. Mole weight: 463.53.
Palbociclib Pyridine N-Oxide
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. CAS No. 2098673-40-4. Molecular formula: C24H29N7O3. Mole weight: 463.54.
Palbociclib Sulfamic Acid
Palbociclib Sulfamic Acid is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-sulfonic acid. Grades: > 95%. CAS No. 2204863-10-3. Molecular formula: C24H29N7O5S. Mole weight: 527.61.
PALDA
PALDA is an endogenous lipid and it can potentiate effects of endovanilloids at TRPV1 receptors. Synonyms: N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide. Grades: ≥98% by HPLC. CAS No. 136181-87-8. Molecular formula: C24H41NO3. Mole weight: 391.59.
PALDA
PALDA. Group: Biochemicals. Grades: Purified. CAS No. 136181-87-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Paldimycin
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- (2-methylpropanoyloxy) ethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- [ (2S) -2-methylbutanoyl] oxyethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid. CAS No. 102426-96-0. Molecular formula: C87H126N8O46S6. Mole weight: 2212.34.
Paldimycin A
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1-alpha; L-Cysteine, N-acetyl-, [2-[[2- (acetylamino)-2-carboxyethyl]thio]-1-carboxypropyl]carbamodithioate (ester), 4'-ester with 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[1-(2-methyl-1-oxobutoxy)ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4''-C-((2S)-2-methylbutyrate), S-ester with N-acetyl-L-cysteine. CAS No. 101411-70-5. Molecular formula: C44H64N4O23S3. Mole weight: 1113.18.
Paldimycin B
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1-Beta; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4'-C-isobutyrate, S-ester with N-acetyl-L-cysteine; L-Cysteine, N-acetyl-, (2-((2-(acetylamino)-2-carboxyethyl)thio)-1-carboxypropyl)carbamodithioate (ester), 1'-4'-ester with 5-(6-O-acetyl-3-O-(2,6-dideoxy-3-O-methyl-4-C-(1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid. CAS No. 101411-71-6. Molecular formula: C43H62N4O23S3. Mole weight: 1099.16.
Palicourein
Palicourein is an antimicrobial peptide found in Palicourea condensata (Cappel), and has antiviral activity. Synonyms: cyclo[Ala-Ala-Leu-Gly-Cys(1)-Thr-Cys(2)-Asp-Asp-Arg-Ser-Asp-Gly-Leu-Cys(3)-Lys-Arg-Asn-Gly-Asp-Pro-Thr-Phe-Cys(1)-Gly-Glu-Thr-Cys(2)-Arg-Val-Ile-Pro-Val-Cys(3)-Thr-Tyr-Ser]; (cyclo)-AALGC (1)TC (2)DDRSDGLC (3)KRNGDPTFC (1)GETC (2)RVIPVC (3)TYS- (cyclo); cyclo[L-alanyl-L-alanyl-L-leucyl-glycyl-L-cysteinyl-L-threonyl-L-cysteinyl-L-alpha-aspartyl-L-alpha-aspartyl-L-arginyl-L-seryl-L-alpha-aspartyl-glycyl-L-leucyl-L-cysteinyl-L-lysyl-L-arginyl-L-asparagyl-glycyl-L-alpha-aspartyl-L-prolyl-L-threonyl-L-phenylalanyl-L-cysteinyl-glycyl-L-alpha-glutamyl-L-threonyl-L-cysteinyl-L-arginyl-L-valyl-L-isoleucyl-L-prolyl-L-valyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-seryl] (5->24),(7->28),(15->34)-tris(disulfide). Grades: >85%. CAS No. 331714-57-9. Molecular formula: C159H248N48O55S6. Mole weight: 3904.35.
Palifosfamide
Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Synonyms: Isophosphamide mustard; Isophosphoramide mustard; IPAM; bis(2-chloroethylamino)phosphinic acid. Grades: ≥ 98%. CAS No. 31645-39-3. Molecular formula: C4H11Cl2N2O2P. Mole weight: 221.018.
Palifosfamide
Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Isophosphoramide mustard; IPM; ZIO-201. CAS No. 31645-39-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14798.
Palifosfamide tromethamine
Palifosfamide tromethamine is a synthetic mustard compound with potential antineoplastic activity. It is an active metabolite of ifosfamide covalently linked to the amino acid lysine for stability. It inhibits DNA replication and cell death. It is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. It may overcome the tumor resistance seen with ifosfamide. It was developed by Dekk-Tec and in clinic phase 3 with no progress. Uses: Palifosfamide tromethamine has potential antineoplastic activity. Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol;Bis(2-chloroethylamino)phosphinic acid;ZIO201;ZIO-201;NSC297900;NSC-297900;N,N'-Bis(2-chloroethyl)phosphorodiamidic acid. Grades: >98%. CAS No. 1070409-31-2. Molecular formula: C8H22Cl2N3O5P. Mole weight: 342.15.
Paliogen Black-S0084
Paliogen Black-S0084. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67075-37-0. Molecular Formula: C40H26N2O4. Mole Weight: 598.66. Catalog: APB67075370.