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| Product | Description | |
|---|---|---|
| M 084 hydrochloride | M 084 hydrochloride is a TRPC4/5 channel blocker with IC50 values of 3.7-10.3 and 8.2 μM, respectively. It weakly blocks TRPC3 channels. It has rapid anxiolytic and antidepressant effects in vivo. It is a useful intermediate. Synonyms: M 084 hydrochloride; M084 hydrochloride; M-084 hydrochloride; N-Butyl-1H-benzimidazol-2-amine hydrochloride. Grades: ≥99% by HPLC. Molecular formula: C11H16N3Cl. Mole weight: 225.72. |  |
| M1001 | M1001 Inhibitor. Uses: Scientific use. Product Category: T7802. CAS No. 874590-32-6. |  |
| M-110 | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC 50 =47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC 50 s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC 50 s of 0.6 to 0.9 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395048-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12830. |  |
| M-110 | M-110, a PIM kinases inhibitor, has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of Wnt/β-catenin. IC50: 0.6 to 0.9 uM. Uses: M-110 is a pim kinases inhibitor that has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of wnt/β-catenin. Synonyms: M-110; M 110; M110; SCHEMBL16410885; SCHEMBL17821539; N'-[(1E)-1-(4-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)propyl]-2-(3-morpholin-4-ylpropylamino)pyridine-4-carbohydrazide. Grades: 98%. CAS No. 1395048-49-3. Molecular formula: C22H28ClN5O3. Mole weight: 445.95. | |
| M1145 | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a K i of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (K i =587 nM) and a 76-fold higher affinity over GalR3 (K i =497 nM). M1145 has an additive effect on the signal transduction of galanin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1172089-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1135. | |
| M 1145 | M 1145. Group: Biochemicals. Grades: Purified. CAS No. 1172089-00-7. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| M 1145 | M 1145 is a selective and potent galanin receptor 2 (GAL2) agonist with Ki value of 6.55 nM and EC50 value of 38 nM. It has an additive effect on the signal transduction of galanin. Synonyms: M 1145; M1145; M-1145. CAS No. 1172089-00-7. Molecular formula: C128H205N37O32. Mole weight: 2774.26. | |
| M-13-1 | It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075. Synonyms: 4,11-Dihydroxy-2,8-dimethyl-7-methoxynaphthacene-5,12-dione. Molecular formula: C21H16O5. Mole weight: 348.35. | |
| M-230B | M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity. Molecular formula: C35H59NO8. Mole weight: 621.84. | |
| M 24 | M 24 is the first selective AT2 receptor agonist (Ki 0.4nM and 10.000 nM for AT2 and AT1 respectively). M 24 effects against endothelial inflammation and leukocyte adhesion both in vitro and in vivo. Synonyms: M 24; M24; M-24; butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate. Grades: 98%. CAS No. 477775-14-7. Molecular formula: C23H29N3O4S2. Mole weight: 475.62. | |
| M 25 | M 25 is a potent Smoothened (Smo) receptor antagonist with IC50 value of 5 nM. It inhibits the Hedgehog signaling pathway. It also inhibits Shh induced Gli luciferase reporter activity in Shh-light 2 cells. It antagonizes GSA-10 and SAG-mediated differentiation of the C3H10T1/2 cell line. Synonyms: M 25; M25; M-25; N-[[1-(2-Methoxyphenyl)-1H-indazol-5-yl]methyl]-2-propylpentanamide. Grades: ≥98% by HPLC. Molecular formula: C23H29N3O2. Mole weight: 379.50. | |
| M 25 | M 25. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| m27,3'-OGP3G (ARCA Cap Analog) | m27,3'-OGP3G (ARCA Cap Analog), renowned for its exceptional properties, is a cap analog. Its omnipresence is felt in various research arenas, permeating the realms of mRNA structure investigation, protein interactions exploration and viral replication mechanism elucidation. Synonyms: mG(5')ppp(5')G; P; -(5'-(3'-O-methyl)-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 400806-46-4. Molecular formula: C22H31N10O18P3(free acid). Mole weight: 816.46 (free acid). | |
| m27,3'-OGP3G (ARCA Cap Analog) - solution | m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Synonyms: mG(5')ppp(5')G; P; -(5'-(3'-O-methyl)-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 98 % by HPLC. Molecular formula: C22H31N10O18P3(free acid). Mole weight: 816.46 (free acid). | |
| M2I-1 | M2I-1 is a protein-protein interaction inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. Synonyms: 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dioneMLS000572003M2I-1; M2I1; M2I 1. Mad2 Inhibitor-1.SMR0001940225-[4-(diisobutylamino)-3-nitrobenzylidene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione6063-97-4AC1METFSMLS003905101CHEMB. CAS No. 312271-03-7. Molecular formula: C19H24N4O4S. Mole weight: 404.48. | |
| M2 ion channel blocker | M2 ion channel blocker is an antiviral agent that works through blocking the activity of M2 ion channel. Uses: M2 ion channel blocker is an antiviral agent that works through blocking the activity of m2 ion channel. Synonyms: methyl(2S)-2-(1-adamantylmethylamino)-3-(1H-imidazol-5-yl)propanoate; 1190215-03-2; CHEMBL2324198; SCHEMBL15029083; 3801AH; W-6012; W 6012; W6012. Grades: 95%. CAS No. 1190215-03-2. Molecular formula: C18H27N3O2. Mole weight: 317.43. | |
| M2N12 | M2N12 is a potent and selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C) with IC50 of 0.09 ?μM. M2N12 exhibits anti-tumor activity. CAS No. 2376577-06-7. Molecular formula: C20H16ClN5O2. Mole weight: 393.83. | |
| m32.2.7GP3G (Trimethylated Cap Analog) | m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Synonyms: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid). | |
| M344 | M344 is a potent HDAC inhibitor, which can also induce expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptosis, in MCF-7 cells. Synonyms: M 344; M-344; Histone Deacetylase Inhibitor III. Grades: >98%. CAS No. 251456-60-7. Molecular formula: C16H25N3O3. Mole weight: 307.39. | |
| M344 | An amide analog of Trichostatin A that potently Inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50 = 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2uM) of murine erythroleukemia cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 251456-60-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M344 | M344 (D 237) is an inhibitor of histone deacetylase ( IC 50 =100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13506. | |
| M 344 | M 344. Group: Biochemicals. Grades: Purified. CAS No. 251456-60-7. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| m-[[[(3-Heptadecyl-1,5-dihydro-5-thioxo-4H-1,2,4-triazol-4-yl)amino]carbonyl]amino]benzenesulfonyl fluoride | m-[[[(3-Heptadecyl-1,5-dihydro-5-thioxo-4H-1,2,4-triazol-4-yl)amino]carbonyl]amino]benzenesulfonyl fluoride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 245-670-7, CID3034339, 23455-88-1, m-((((3-Heptadecyl-1,5-dihydro-5-thioxo-4H-1,2,4-triazol-4-yl)amino)carbonyl)amino)benzenesulphonyl fluoride. Product Category: Heterocyclic Organic Compound. CAS No. 23455-88-1. Molecular formula: C26H42FN5O3S2. Mole weight: 555.771783 [g/mol]. Purity: 0.96. IUPACName: 4-[(3-heptadecyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)carbamoylamino]benzenesulfonyl fluoride. Canonical SMILES: CCCCCCCCCCCCCCCCCC1=NNC(=S)N1NC(=O)NC2=CC(=CC=C2)S(=O)(=O)F. ECNumber: 245-670-7. Product ID: ACM23455881. Alfa Chemistry ISO 9001:2015 Certified. |  |
| m-3M3FBS | m-3M3FBS. Group: Biochemicals. Grades: Purified. CAS No. 200933-14-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| m-3M3FBS | m-3M3FBS is a direct activator of phospholipase C (PLC) that stimulates the increase in cytoplasmic calcium, inositol phosphate formation and superoxide generation in a variety of cell types. It is used in biological studies on Ca2+ homeostasis independently of phospholipase C activation. It is also used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122. It has also been used for intracellular calcium analysis and MAP kinase assay in 293T cells. It also inhibits growth of the leukemic cell lines U937 and THP-1. Synonyms: m-3M3FBS; m 3M3FBS; m3M3FBS; 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide; N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide. Grades: ≥99% by HPLC. CAS No. 200933-14-8. Molecular formula: C16H16F3NO2S. Mole weight: 343.36. | |
| M3N2 (Man-3) Glycan, 2-AA labelled | M3N2 (Man-3) Glycan, 2-AA labelled is a biologically significant oligosaccharide mainly used in biomedical research. It's frequently applied in glycan profiling for diagnostics and therapeutic applications, particularly in cancer and inflammatory disease studies. | |
| M3N2 (Man-3) Glycan, 2-AB labelled | 2-AB labeled core pentasaccharide is present in most N-linked oligosaccharides. Synonyms: M3N2 Glycan, 2-AB labelled. | |
| M3 receptor antagonist 1 | An antagonist of muscarinic M3-receptor. Synonyms: CHF5407; CHF-5407; CHF 5407; 1-Azoniabicyclo[2.2.2]octane, 3-[[[ (3-fluorophenyl) [ (3, 4, 5-trifluorophenyl) methyl]amino]carbonyl]oxy]-1-[2-oxo-2- (2-thienyl) ethyl]-, bromide,(3R)-. CAS No. 1004312-94-0. Molecular formula: C27H25BrF4N2O3S. Mole weight: 613.46. | |
| M40 | M40. Group: Biochemicals. Grades: Purified. CAS No. 143896-17-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M40 | M40 is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: M 40; M-40; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2; L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-; Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide; M 40 (peptide). Grades: ≥95%. CAS No. 143896-17-7. Molecular formula: C95H146N22O24. Mole weight: 1980.31. | |
| M40 acetate | M40 acetate is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2.CH3CO2H; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide acetic acid; M 40 acetate. Grades: ≥95%. Molecular formula: C96H149N23O26. Mole weight: 2041.38. | |
| m-[4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-[4-[(1-oxooctadecyl)amino]phenyl]-1H-pyrazol-1-yl]benzenesulfonic acid | m-[4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-[4-[(1-oxooctadecyl)amino]phenyl]-1H-pyrazol-1-yl]benzenesulfonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 305-653-8, CID3024410, 94944-75-9, m-(4-(2-Cyanoethyl)-4,5-dihydro-5-oxo-3-(4-((1-oxooctadecyl)amino)phenyl)-1H-pyrazol-1-yl)benzenesulphonic acid. Product Category: Heterocyclic Organic Compound. CAS No. 94944-75-9. Molecular formula: C36H50N4O5S. Mole weight: 650.871000 [g/mol]. Purity: 0.96. IUPACName: 3-[4-(2-cyanoethyl)-3-[4-(octadecanoylamino)phenyl]-5-oxo-4H-pyrazol-1-yl]benzenesulfonic acid. Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NC1=CC=C(C=C1)C2=NN(C(=O)C2CCC#N)C3=CC(=CC=C3)S(=O)(=O)O. Density: 1.17g/cm³. ECNumber: 305-653-8. Product ID: ACM94944759. Alfa Chemistry ISO 9001:2015 Certified. | |
| M-4365 A1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Molecular formula: C31H53NO8. Mole weight: 567.75. | |
| M-4365 G1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity. Molecular formula: C31H53NO7. Mole weight: 551.75. | |
| M-4365 G2 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Synonyms: SCHEMBL192993. Molecular formula: C31H51NO8. Mole weight: 565.74. | |
| m-[[4-[[4-[(2-Cyanoethyl)ethylamino]-O-tolyl]azo]-1-naphthyl]azo]benzenesulfonic acid | m-[[4-[[4-[(2-Cyanoethyl)ethylamino]-O-tolyl]azo]-1-naphthyl]azo]benzenesulfonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-[(e)-{4-[(e)-{4-[(2-cyanoethyl)(ethyl)amino]-2-methylphenyl}diazenyl]naphthalen-1-yl}diazenyl]benzenesulfonic acid, 27452-68-2, 28217-33-6, Benzenesulfonic acid, 3-((4-((4-((2-cyanoethyl)ethylamino)-2-methylphenyl)azo)-1-naphthalenyl)azo)-, Benzenesulfonic acid, 3-(2-(4-(2-(4-((2-cyanoethyl)ethylamino)-2-methylphenyl)diazenyl)-1-naphthalenyl)diazenyl)-, Benzenesulfonic acid, 3-[[4-[[4-[(2-cyanoethyl)ethylamino]-2-methylphenyl]azo]-1-naphthalenyl]azo]-, Benzenesulfonic acid, 3-[2-[4-[2-[4-[(2-cyanoethyl)ethylamino]-2-methylphenyl]diazenyl]-1-naphthalenyl]diazenyl]-, AC1L3LYE, AC1Q6X27, CTK8D6047, EINECS 248-466-6, AR-1F0779, m-((4-((4-((2-Cyanoethyl)ethylamino)-o-tolyl)azo)-1-naphthyl)azo)benzenesulphonic acid, 3-[[4-[[4-[2-cyanoethyl(ethyl)amino]-2-methylphenyl]diazenyl]naphthalen-1-yl]diazenyl]benzenesulfonic acid. Product Category: Heterocyclic Organic Compound. CAS No. 27452-68-2. Molecular formula: C28H26N6O3S. Mole weight: 526.609440 [g/mol]. Purity: 0.96. IUPACName: 3-[[4-[[4-[2-cyanoethyl(ethyl)amino]-2-methylphenyl]diazenyl]naphthalen-1-yl]diazenyl]benzenesulfonic acid. Canonical SMILES: CCN(CCC#N)C1=CC(=C(C=C1)N=NC2=CC=C(C3=CC=CC=C32)N=NC4=CC(=CC=C4)S(=O)(=O)O)C. | |
| M47 | M47 is a small molecule that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890808-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148764. | |
| m4CzIPN | m4CzIPN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4,5,6-Tetrakis(3,6-dimethyl-9H-carbazol-9-yl)isophthalonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1469703-61-4. Molecular formula: C64H48N6. Mole weight: 901.11 g/mol. Product ID: ACM1469703614-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| M50054 | M50054 is a cell-permeable inhibitor of apoptosis induction, blocking the caspase-3 activation. It was shown to suppress apoptosis induced by various stimuli via inhibiting caspase-3. Synonyms: Apoptosis Inhibitor; 2,2'-Methylenebis(cyclohexane-1,3-dione); 2-[(2,6-dioxocyclohexyl)methyl]cyclohexane-1,3-dione; 2,2'-methylenedicyclohexane-1,3-dione; 2-[(2,6-Dioxocyclohexyl)methyl]cyclohexane-1,3-dione. Grades: ≥98%. CAS No. 54135-60-3. Molecular formula: C13H16O4. Mole weight: 236.3. | |
| M617 | M617. Group: Biochemicals. Grades: Purified. CAS No. 860790-38-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M617 | M617 is a selective galanin receptor 1 (GAL1) agonist, with K i s of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 860790-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1131. | |
| M617 | M617 is a chimeric peptide that acts as a selective galanin GAL1 receptor agonist with Ki values of 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively. It enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain. Synonyms: M617; M 617; M-617; Galanin(1-13)-Gln14-bradykinin(2-9)amide. CAS No. 860790-38-1. Molecular formula: C112H161N29O28. Mole weight: 2361.68. | |
| M62812 | M62812 is a toll-like receptor 4 (TLR4) transduction inhibitor. It inhibits LPS-induced NF-κB activation in HEK293 cells with IC50 value of 2.4 μg/mL). It also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. It could prolong survival in a mouse septic shock model. It suppresses endothelial cell and leukocyte activation, preventing lethal septic shock in mice. Synonyms: 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine dihydrochloride; 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine Hydrochloride (1:2). Grades: ≥98% by HPLC. CAS No. 613263-00-6. Molecular formula: C13H13N3OSCl2. Mole weight: 330.23. | |
| M65 | M65 is a potent and specific antagonist of PAC1 receptor. Synonyms: PAC1 Receptor Antagonist M65; H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys32). Grades: ≥95%. CAS No. 1872440-65-7. Molecular formula: C205H326N64O61S5. Mole weight: 4823.57. | |
| m7(3'OMeG)(5')ppp(5')(2'OMeA)pG | Used for in vitro transcription of 5'-capped mRNA to produce a Cap 1 structure. EZ Cap reagent AG 3'OMe should be used with the specific starting sequence 5'AG 3'. Synonyms: EZ Cap Reagent AG (3'OMe)[m7 (3'OMeG) (5')ppp (5') (2'OMeA)pG]. Grades: ≥95% by AX-HPLC. Molecular formula: C33H45N15O24P4 (free acid). Mole weight: 1159.71 (free acid). | |
| M7824 | M7824 is a bifunctional anti-PD-L1/TGFβ Trap fusion protein that comprises the extracellular domain of human TGFβRII (TGFβ Trap) linked to the C-terminus of human anti-PD-L1 heavy chain (αPD-L1). M7824 can be used in the treatment of various cancers. Synonyms: MSB0011395C. | |
| m7G(5')ppp(5')(2'OMeA)pG | Used for in vitro transcription of 5'-capped mRNA to produce a Cap 1 structure. Compared with the Cap 0 structure, the mRNA with Cap 1 structure is more suitable for the mammalian system and has a higher transcription efficiency. Synonyms: EZ Cap Reagent AG [m7G(5')ppp(5')(2'OMeA)pG]. Grades: ≥95% by AX-HPLC. Molecular formula: C32H43N15O24P4 (free acid). Mole weight: 1145.68 (free acid). | |
| m7GDP | m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Synonyms: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H19N5O11P2. Mole weight: 459.24. | |
| m7GMP | m7GMP, the eminent molecule widely employed in the biomedical sphere, holds paramount importance in the production of mRNA and viral RNA. Its indispensable contribution lies within the realm of cap-dependent translation initiation, where it assumes a distinctive stance as the prime target for recognition by the initiation factor eIF4E. Wholly engrossed in the intricate domains of RNA modification and processing, m7GMP exhibits vast prospects for the research of RNA-associated afflictions, including the notorious cancer and pernicious viral infections. Synonyms: 7-methyl-guanosine-5'-monophosphate, triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 47442-17-1. Molecular formula: C11H16N5O8P (free acid). Mole weight: 377.25 (free acid). | |
| m7GMP-α-F | m7GMP-α-F is an esteemed bioactive nucleotide analog extensively employed, unveiling its true compound as a formidable antagonist of RNA polymerase. Moreover, the scientific community harnesses the power of m7GMP-α-F for intricate studies pertaining to gene expression regulation and the labyrinthine world of RNA processing. Synonyms: (m7GpF); 7-methyl-guanosine-5'-(α-fluoro)-monophosphate; 7-methyl-guanosine-5'-(1-fluoro)-monophosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C11H16FN5O7P. Mole weight: 380.25. | |
| m7GP3C | m7GP3C is a cutting-edge compound developed for studying the metastatic stage of breast cancer. Its mechanism of action involves the potent inhibition of DNA topoisomerase II, thereby impeding DNA replication and effectively inducing the eradication of malignant cells. Synonyms: P; -(5'-7-methyl-guanosyl) P; -(5'-(cytidyl))triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 70441-86-0. Molecular formula: C20H29N8O18P3(free acid). Mole weight: 762.41 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) | m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Synonyms: mG(5')ppp(5')G; P; -(5'-7-methyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3(free acid). Mole weight: 802.43 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) - solution | | |
| m7GP5G | m7GP5G is a synthetic molecule used as a research tool in the biomedical industry to study various cellular processes, including DNA repair and transcription regulation. It has also shown potential in cancer treatment due to its ability to inhibit the activity of certain oncogenes. Clinical trials are ongoing to investigate its efficacy in treating breast, lung, and prostate cancers. Synonyms: P; -(5'-7-Methyl-Guanosyl)-P; -(5'-Guanosyl)-pentaphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C21H32N10O24P5(free acid). Mole weight: 963.40 (free acid). | |
| m7GTP | m7GTP, the nucleoside triphosphate that has a critical role in RNA synthesis and gene expression regulation, is also attributed with virus fighting capabilities and cancer cell apoptosis induction. With its dual functions as a precursor and modifier in RNA synthesis and as an inhibitor in viral infections, m7GTP shows promise in the treatment of diseases such as cancer. Synonyms: 7-Methyl-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 26554-26-7. Molecular formula: C11H18N5O14P3(free acid). Mole weight: 537.21 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4- Cy5 | m7GTP-γ-aminophenyl-PEG4- Cy5 is a vital tool, commonly used for synthesizing fluorescent oligonucleotides. This product aids in the study of RNA and mRNA localization, structure and function within cells. It facilitates the detection and imaging of RNA molecules, providing valuable insights into gene expression, RNA processing and RNA-protein interactions. This versatile tool greatly contributes to advancing molecular biology research and drug discovery aimed at targeting RNA-related diseases. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG; ]-5'-triphosphate - Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C61H82N9O26P3S2(free acid). Mole weight: 1513.40 (free acid). | |
| M871 | M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 ( GalR2 ) antagonist. M871 exhibits K i values of 13.1 nM and 420 nM for GalR2 and GalR1 , respectively. M871 can be used for research on GalR2 -related diseases (such as epilepsy, pain) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide. CAS No. 908844-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1130. | |
| M871 | M871. Group: Biochemicals. Grades: Purified. CAS No. 908844-75-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M871 | M871 is a selective galanin GAL2 receptor antagonist with Ki values of 420 and 13.1 nM for GAL1 and GAL2 receptors respectively. It blocks the pro-nociceptive effect of GAL2 receptor agonists. Synonyms: Galanin(2-13)Glu-His-(Pro)3(Ala-Leu)2Ala-amide. Grades: >98%. CAS No. 908844-75-7. Molecular formula: C108H163N27O28. Mole weight: 2287.64. | |
| M-89 | M-89 is a highly potent and specific menin inhibitor, with a K d of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2363165-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128347. | |
| M8 B hydrochloride | M8 B hydrochloride is a selective and potent channel blocker of transient receptor potential melastatin 8 (TRPM8). It blocks cold-induced and icilin or methol-induced activation of rat, human, and murine TRPM8 channels. It displays no effect at other TRP channels with IC50 value of > 20 mM. It decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice. It may be used to induce therapeutic hypothermia, which is an effective treatment in cardiac arrest. Synonyms: N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride; N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride; N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide, monohydrochloride. Grades: ≥99% by HPLC. CAS No. 883976-12-3. Molecular formula: C22H25N2O3SCl. Mole weight: 432.96. | |
| M8 B hydrochloride | M8 B hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 883976-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MA144 G2 | MA144 G2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144G2; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,3,6-trideoxy-alpha-L-glycero-hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-hexopyranosyl)oxy)-2,5,7,10-tetrahydroxy-, methyl ester. CAS No. 66808-28-4. Molecular formula: C42H53NO16. Mole weight: 827.87. | |
| MA144 M1 | MA144 M1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1,4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2,5,7-trihydroxy-, methyl ester; aclacinomycin M; MA-144M1. CAS No. 64431-68-1. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
| MA144 M2 | MA144 M2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M2; 1-Hydroxy MA144 M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4) 2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester; MA-144M2. CAS No. 64474-89-1. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA144 S1 | MA144 S1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: aclacinomycin S; Antibiotic MA 144S1; MA 144 S1; L-2-Deoxyfucosyl-L-rhodosaminyl-aklavinone. CAS No. 64431-69-2. Molecular formula: C36H45NO13. Mole weight: 699.74. | |
| MA144 U1 | MA144 U1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144U1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-2,7-dihydroxy-, methyl ester. CAS No. 65222-74-4. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA 2029 | MA 2029 is a novel, potent, selective and competitive motilin receptor antagonist with IC50 value of 4.9 nM. It inhibits motilin-induced duodenal muscle contractions in animal models and colonic and abdominal contractions in rabbits. It may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility such as IBS. It is selective for the motilin receptor over a range of other receptors and ion channels. It is orally active. Synonyms: MA-2029; MA 2029; MA2029; 4-Fluoro-N-methyl-L-phenylalanyl-N-methyl-L-valyl-3-(1,1-dimethylethyl)-N-ethyl-L-tyrosinamide; (2S)-N-[(2S)-3-(3-tert-butyl-4-hydroxyphenyl)-1-(ethylamino)-1-oxopropan-2-yl]-2-[[(2S)-3-(4-fluorophenyl)-2-(methylamino)propanoyl]-methylamino]-3-methylbutanamide. Grades: ≥98% by HPLC. CAS No. 287206-61-5. Molecular formula: C31H45FN4O4. Mole weight: 556.71. | |
| MA 2029 | MA 2029. Group: Biochemicals. Grades: Purified. CAS No. 287206-61-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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