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Itopride-[d6] Hydrochloride is the labelled analogue of Itopride. Itopride is a Dopamine D2 receptor antagonist with anticholinesterase activity used as a gastroprokinetic. Synonyms: Itopride D6 Hydrochloride; N-[[4-[2-(Dimethylamino-d6)ethoxy]phenyl]methyl]-3,4-dimethoxy Benzamide Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1346601-02-2. Molecular formula: C20H21D6ClN2O4. Mole weight: 400.93.
Itopride hydrochloride
Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HSR803. CAS No. 122892-31-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0732.
Itopride hydrochloride
Itopride hydrochloride. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethylamino) ethoxy]phenyl]methyl]-3, 4-dimethoxy benzamide hydrochloride; HSR-803; HC-803. Grades: Highly Purified. CAS No. 122892-31-3. Pack Sizes: 1kg, 2kg, 5kg, 10kg, 25kg. Molecular Formula: C20H27ClN2O4. US Biological Life Sciences.
Dopamine D2-receptor antagonist with anticholinesterase activity. Gastroprokinetic. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethylamino) ethoxy]phenyl]methyl]-3, 4-dimethoxy Benzamide Hydrochloride; HSR-803; HC-803; Itax; Ganaton. Grades: Highly Purified. CAS No. 122892-31-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Itopride N-Oxide
A metabolite of Itopride. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethyloxidoamino) ethoxy]phenyl]methyl]-3, 4-dimethoxybenzamide. Grades: Highly Purified. CAS No. 141996-98-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Itopride N-Oxide
2-(4-((3, 4-Dimethoxybenzamido)methyl)phenoxy)-N, N-dimethylethan-1-amine oxide is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 141996-98-7. Pack Sizes: 1 mg. Product ID: HY-W701323.
Itraconazole
Itraconazole is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain fungal infections, such as: Histoplasmosis. Certain types of mucocutaneouscandidiasis, including esophageal candidiasis (infection of the esophagus) and oropharyngeal candidiasis (infection of part of the throat). Histoplasmosis and mucocutaneous candidiasis can be opportunistic infections (OIs) of HIV. Alternative Names: Oriconazole. Sporanox. Itraconazol. CAS No. 84625-61-6. Product ID: API84625616. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.6. EINECS: 283-347-2. SMILES: CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl. Appearance: White to Off-white Solid. Category: Antifungal APIs.
Itraconazole
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC 50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase ( cytochrome P450 enzyme ), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein ( OSBP ) inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: R51211. CAS No. 84625-61-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17514.
Itraconazole
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C35H38Cl2N8O4. CAS No. 84625-61-6. Prepack ID 45052670-1g. Molecular Weight 705.63. See USA prepack pricing.
Itraconazole
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiacovid-19 research and reference materialseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Candistat, Spherazole CR, Sporanox, R 51211, Orungal, Itralek, Oriconazole, cis-Itraconazole, Orungamin, Itrac, Spherazole IR, Itrizole, Sporonox,Itraconazole, 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-, Traconal, 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-, rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one, Sporamelt, Canditral, Triasporin, Sempera, SUBA Itraconazole, Sporal, Cladosal 100, Sporanox IV.
5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C35H38Cl2N8O4. CAS No. 84625-61-6. Prepack ID 45052670-5g. Molecular Weight 705.63. See USA prepack pricing.
Itraconazole
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-;(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one. Product Category: Inhibitors. Appearance: Off-white crystalline solid. CAS No. 84625-61-6. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.63. Purity: 0.9981. Canonical SMILES: ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7. Density: 1.4 g/cm³. ECNumber: 283-347-2. Product ID: ACM84625616. Alfa Chemistry ISO 9001:2015 Certified.
Itraconazole-[d3]
Itraconazole-[d3] is the labelled analogue of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It has antifungal activity. It is a COVID-19-related research product. Synonyms: Itraconazole D3; (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methyl-d3-propyl)-3H-1,2,4-triazol-3-one; Itrizole-d3; Oriconazole-d3; Sporamelt-d3; Sporanox-d3; Triasporin-d3; Itraconazole-d3. Grade: 98%. CAS No. 1217512-35-0. Molecular formula: C35H35D3Cl2N8O4. Mole weight: 708.67.
Itraconazole-[d4]
Itraconazole-[d4] is the labelled analogue of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID-19-related research product. Synonyms: Sporanox D4. Grade: 98% by CP; 98% atom D. Molecular formula: C35H34D4Cl2N8O4. Mole weight: 709.66.
Itraconazole-d5
An isotopically labeled, orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Itraconazole-[d5]
Itraconazole-[d5] is the labelled analogue of Itraconazole. Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID-19-related research product. Synonyms: (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl-d5)-3H-1,2,4-triazol-3-one; Itrizole-d5; Oriconazole-d5; R-51211-d5; Sporamelt-d5; Sporanox-d5; Triasporin-d5. Grade: 98% by CP; 98% atom D. CAS No. 1217510-38-7. Molecular formula: C35H33D5Cl2N8O4. Mole weight: 710.66.
Itraconazole for system suitability
Itraconazole for system suitability. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Itraconazole. Product Category: Heterocyclic Organic Compound. Appearance: off-White crystalline solid. CAS No. 84625-61-5. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.633. Purity: 0.96. IUPACName: itraconazole. Density: 1.4 g/cm³. Product ID: ACM84625615. Alfa Chemistry ISO 9001:2015 Certified.
Itraconazole Impurity 10
Itraconazole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 154003-23-3. Molecular formula: C20H19Cl2N3O5S. Mole weight: 484.35. Catalog: APB154003233.
Itraconazole Impurity 22
Itraconazole Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106461-41-0. Molecular formula: C22H27N5O2. Mole weight: 393.49. Catalog: APB106461410.
Itraconazole Impurity 23
Itraconazole Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103661-14-9. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.25. Catalog: APB103661149.
Itraconazole (Oriconazole, Sporanox, Triasporin)
An orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Alternative Names: Oriconazole, Sporanox, Triasporin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Itraconazole solution
2.0 mg/mL (Methanol with 1% 1M HCl), ampule of 1 mL, certified reference material. Group: Antifungals standards.
Itraconazole System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
ITSA-1
ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA)-induced cell cycle arrest, histone acetylation, and transcriptional activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 200626-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100508.
Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 200626-61-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Iturin A
Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322.
ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IU1
IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IU1
IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817.
IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 ?M. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 ?M. IU1-47 induces tau elimination in cultured neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 670270-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122243.
IUN78876
IUN78876, also known as 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one is a chemical reagent for research use. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IUN78876; IUN-78876; IUN 78876. Product Category: Others. Appearance: Solid powder. CAS No. 1638178-87-6. Molecular formula: C23H22F2N4O. Mole weight: 408.45. Purity: >98%. IUPACName: 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one. Canonical SMILES: O=C1N(CC2=CC=C(F)C=C2F)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4. Product ID: ACM1638178876. Alfa Chemistry ISO 9001:2015 Certified.
Ivabradine
Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155974-00-8. Pack Sizes: 1 mg. Product ID: HY-B0162.
Ivabradine-[d3]
Ivabradine-[d3] is the labelled analogue of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Synonyms: Ivabradine D3; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d3 Hydrochloride; Corlentor-d3; Procoralan-d3; Ivabradine-d3. Grade: >95%. CAS No. 1217977-70-2. Molecular formula: C27H33D3N2O5. Mole weight: 471.60.
Ivabradine-[d3] Hydrochloride
Ivabradine-[d3] Hydrochloride is the labelled salt of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Uses: The hydrochloride salt form of isotope labelled ivabradine. Synonyms: Ivabradine-D3 Hydrochloride; Ivabradin D3 HCl; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3 Hydrochloride; Procoralan-d3 Hydrochloride. Grade: >95%. CAS No. 1217809-61-4. Molecular formula: C27H34D3ClN2O5. Mole weight: 508.06.
Ivabradine-d3 Hydrochloride
Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivabradine-[d6] hydrochloride
Ivabradine-[d6] hydrochloride is the labelled analogue of Ivabradine Hydrochloride. Ivabradine hydrochloride has been used as a potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel (HCN)2 blocker in embryoid body (EB) and rat engineered heart tissue (EHT). Synonyms: Ivabradine D6 hydrochloride; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d6 hydrochloride; Corlentor-d6; Procoralan-d6. Grade: 98% by CP. CAS No. 2070009-63-9. Molecular formula: C27H30D6N2O5.HCl. Mole weight: 511.08.
Ivabradine hydrochloride
Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grade: >98%. CAS No. 148849-67-6. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05.
Ivabradine hydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-1g. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine hydrochloride
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-100mg. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine hydrochloride
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148849-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0162A.
Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ivacaftor
Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences.
Worldwide
Ivacaftor
Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017.
Ivacaftor Carboxylic Acid
Ivacaftor Carboxylic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethyl-, 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid, 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethylbenzeneacetic acid, Ivacaftor carboxylic acid, Ivacaftor impurity 1. CAS No. 1246213-24-0. IUPAC Name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. Molecular formula: C24H26N2O5. Mole weight: 422.47. Catalog: APS1246213240. SMILES: CC(C)(C)c1cc(c(O)cc1NC(=O)C2=CNc3ccccc3C2=O)C(C)(C)C(=O)O. Format: Neat.
Ivacaftor-d18
Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences.
Worldwide
Ivacaftor-[d18]
Ivacaftor-[d18] is the labelled analogue of Ivacaftor. Ivacaftor is an orally bioavailable potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) that improves chloride transport. Synonyms: Ivacaftor D18. Grade: 95% by HPLC; 95% atom D. CAS No. 1413431-05-6. Molecular formula: C24H10D18N2O3. Mole weight: 410.6.
Ivacaftor-d19
Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VX-770-d19. CAS No. 1413431-22-7. Pack Sizes: 5 mg; 1 mg. Product ID: HY-13017S1.
Ivacaftor impurities5
Ivacaftor impurities5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.48. Catalog: APB1246213240.
Ivacaftor impurities6
Ivacaftor impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB1246213239.
Ivacaftor impurities7
Ivacaftor impurities7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB1246213411.
Ivacaftor N-Glucuronide
Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences.
Worldwide
Ivarmacitinib
Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2 , 77-fold for JAK3 , 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR0302. CAS No. 1445987-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112724.
Ivebradine impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1086026-31-4. Molecular formula: C27H34N2O5. Mole weight: 466.58. Catalog: APB1086026314.
Ivermectin
Ivermectin is a positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor. CAS No. 70288-86-7. Product ID: API70288867. SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Standard: USP. Category: Active Pharmaceutical Ingredients.
Ivermectin
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X 4 and the α7 neuronal nicotinic acetylcholine receptor ( nAChRs ). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import [1] [2] [3] [4]. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MK-933; CD-5024; K-237. CAS No. 70288-86-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-15310.
Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grade: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Ivermectin
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H74O14. CAS No. 70288-86-7. Prepack ID 21022571-1g. Molecular Weight 875.09. See USA prepack pricing.
Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Ivermectin; Dihydroavermectin B1a; 22,23-Dihydroavermectin B1a; Ivermectin Component B1a; avermectin H2B1a; 5-O-demethyl-22,23-dihydroavermectin A1a; MK-933; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydroavermectin B(1)a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.; Ivermectin (IVM); IVM; dihydro avermectin Bla; H2B1a; Ivermectin (MK-0933). Grade: >95% by HPLC. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09.
Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
Worldwide
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. Purity: 0.85. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-1. Alfa Chemistry ISO 9001:2015 Certified.
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) [1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71827-03-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-126937.