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| Product | Description | |
|---|---|---|
| I-CBP 112 | I-CBP112 has been found to be a CBP/p300 bromodomain inhibitor and could reduce the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells. Synonyms: I-CBP112; I-CBP-112; I-CBP 112. 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one. Grades: ≥98% by HPLC. CAS No. 1640282-31-0. Molecular formula: C27H36N2O5. Mole weight: 468.59. |  |
| I-CBP112 hydrochloride | I-CBP112 is a selective inhibitor of CBP and EP300 bromodomain (Kds = 0.142 and 0.625 μM, respectively). CBP and EP300 are histone acetyltransferase (HAT) enzymes that serve as transcriptional coactivators and have been found to be dysregulated in cancer and other diseases. Synonyms: 1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one hydrochloride. Grades: ≥90%. CAS No. 2147701-33-3. Molecular formula: C27H36N2O5·HCl. Mole weight: 505.1. | |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Synonyms: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52. | |
| Icenticaftor | Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC 50 s of 79 nM and 497 nM for F508del and G551D CFTR , respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QBW251. CAS No. 1334546-77-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109177. |  |
| ICG001 | ICG001 Inhibitor. Uses: Scientific use. Product Category: T2237. CAS No. 847591-62-2. |  |
| ICG-001 | ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and binds to cyclic AMP responsive element binding-binding protein (CBP)-mediated transcription with IC50 value of 3 μM. ICG-001 has been demonstrated to inhibit gastric cancer cell growth and reduce chemoresistance of cancer stem cell-like population. Synonyms: ICG 001; (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide. Grades: >98%. CAS No. 780757-88-2. Molecular formula: C33H32N4O4. Mole weight: 548.63. | |
| ICG-001 | ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC 50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 780757-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14428. | |
| I-Cholestane | Synonyms: i-Cholestane; 3,5-Cyclocholestane; (3aR, 3bS, 5aR, 6R, 8aS, 8bS) -3a, 5a-dimethyl-6- ( (R) -6-methylheptan-2-yl) hexadecahydrocyclopenta [a]cyclopropa [2, 3]cyclopenta [1, 2-f]naphthalene; (3α,5α)-3,5-Cyclocholestane. CAS No. 465-56-5. Molecular formula: C27H46. Mole weight: 370.65. | |
| Ichthammol | Ichthammol is an antibacterial, fungicidal, antiinflammatory agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 8029-68-3. Pack Sizes: 100g, 250g. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences. |  Worldwide |
| Ichthammol USP | Ichthammol USP. |  CA, FL & NJ |
| ICI-118551 HCl | A highly selective antagonist for the β2 adrenergic receptors. Binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively). Synonyms: ICI-118551; ICI118551; ICI 118551; ICI-118,551; ICI118,551; ICI 118,551. Grades: 98%. CAS No. 72795-19-8. Molecular formula: C17H28ClNO2. Mole weight: 313.866. | |
| ICI 118551 hydrochloride | ICI 118551 hydrochloride is a highly selective β2 adrenergic antagonist (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively), inhibited cAMP accumulation by 50% (IC50 = 1.5 microM and 1.7 microM, respectively). Uses: A highly selective β2 adrenergic receptor antagonist. Synonyms: ICI 118551 hydrochloride; ICI118551 hydrochloride; ICI-118551 hydrochloride; (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride;(2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol;hydrochloride. Grades: ≥98%. CAS No. 72795-01-8. Molecular formula: C17H27NO2.HCl. Mole weight: 313.86. | |
| ICI 118551 Hydrochloride ((±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol Hydrochloride) | A highly selective antagonist for the beta-2 adrenergic receptors. Binds to the beta-2 subtype with at least 100 times greater affinity than beta-1 or beta-3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257nM for beta-2, beta-1 and beta-3 receptors respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 72795-19-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ICI141292 | ICI141292, also known as Epanolol, is a adrenergic β-antagonist with a greater affinity for β1- than β2-adrenoceptors, which is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. Synonyms: N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide; epanolol; ICI 141,292; ICI 141292; ICI-141,292; N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxyphenylacetamide; Visacor. CAS No. 86880-51-5. Molecular formula: C20H23N3O4. Mole weight: 369.41. | |
| ICI 154,129 | ICI 154,129 is a selective δ opioid antagonist. It is a peptide analog that antagonized the effects of Leu-enkephalin. Uses: Narcotic antagonists. Synonyms: N,N-Di(2-propenyl)-L-Tyr-N-[2-[[(S)-2-[[(S)-1-carboxy-3-methylbutyl]amino]-2-oxo-1-benzylethyl]thio]ethyl]-Gly-NH2; M-154129. Grades: >98%. CAS No. 83420-94-4. Molecular formula: C34H46N4O6S. Mole weight: 638.83. | |
| ICI 162,846 | ICI 162,846 is a potent histamine H2 receptor antagonist. Synonyms: ICI 162,846; ICI162,846; ICI-162,846; N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine; 3-[[Imino[(2,2,2-trifluoroethyl)amino]methyl]amino]-1H-pyrazole-1-pentanamide. CAS No. 84545-30-2. Molecular formula: C11H17F3N6O. Mole weight: 306.29. | |
| ICI 174864 | ICI 174864 is a highly selective, potent δ-receptor antagonist. ICI 174864 is equipotent with naloxone and can not reverse the effect of the μ-agonist [D-Ala2, MePhe4, Gly-Ol5]enkephalin or the κ-agonist-tifluadom [1]. Uses: Scientific research. Group: Peptides. CAS No. 89352-67-0. Pack Sizes: 1 mg. Product ID: HY-101230. | |
| ICI 174,864 | ICI 174,864 is a potent and highly selective δ opioid antagonist. It shows partial agonist in vitro activity at δ receptors at high concentrations. Synonyms: ICI 174,864; ICI174,864; ICI-174,864; N,N-Di-2-propen-1-yl-L-tyrosyl-2-methylalanyl-L-phenylalanyl-L-leucine; NIH 10893; N,N-diallyl-tyrosyl-alpha-aminoisobutyric acid-phenylalanyl-leucine; L-Leucine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-L-phenylalanyl)-; N,N-Diallyl-Tyr-aib-Phe-Leu. Grades: >98%. CAS No. 89352-67-0. Molecular formula: C38H53N5O7. Mole weight: 691.87. | |
| ICI 185,282 | ICI 185,282 is a potent thromboxane receptor antagonist. Synonyms: ICI-185282; ICI 185282; ICI185282; 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid. CAS No. 106393-80-0. Molecular formula: C18H21F3O5. Mole weight: 374.36. | |
| ICI 192,605 | ICI 192,605 is a potent thromboxane A2 receptor antagonist. It can reverse vasoconstriction induced by inhibition of NO production and inhibits platelet aggregation, which leads to an increase in TXA2 release. It also inhibits contractile responses to U 46619. Synonyms: ICI 192605 ; ICI192605; ICI-192605. (4Z)-rel-, 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid; 4-Hexenoic acid, 6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-; 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoic acid; (E)-6-[(2S,4S,5R)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic Acid. Grades: ≥98% by HPLC. CAS No. 117621-64-4. Molecular formula: C22H23ClO5. Mole weight: 402.87. | |
| ICI-198615 | ICI-198615 is a novel, potent and selective peptide leukotriene antagonist. It may be useful for the the treatment of allergic diseases. Uses: Ici-198615 may be useful for the the treatment of allergic diseases. Synonyms: [1-[[2-Methoxy-4-[[ (phenylsulfonyl) amino]carbonyl]phenyl]methyl]-1H-indazol-6-yl]carbamic acid cyclopentyl ester;Cyclopentyl N-[1-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]indazol-6-yl]carbamate;ICI 198615; ICI-198615; ICI198615; ICI-198,615; ZM 198615; ZM-198615. Grades: >98 %. CAS No. 104448-53-5. Molecular formula: C28H28N4O6S. Mole weight: 548.61. | |
| ICI 199441 | ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 115199-84-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101205. | |
| ICI 199,441 hydrochloride | ICI 199,441 hydrochloride is the hydrochloride salt of ICI 199,441, which is a selective and highly potent κ agonist. It is 146-fold more active than U-50488 in vitro. It has a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. It has analgesic properties. Synonyms: ICI 199,441 hydrochloride; ICI199,441 hydrochloride; ICI-199,441 hydrochloride; 3,4-Dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; (S)-3,4-Dichloro-N-methyl-N-[1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 115199-84-3. Molecular formula: C21H25Cl3N2O. Mole weight: 427.80. | |
| ICI-204448 | ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121264-04-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101231. | |
| ICI 204,448 hydrochloride | ICI 204,448 hydrochloride is the hydrochloride salt of ICI 204,448, which is a peripherally acting κ opioid receptor agonist. It does not cross the blood-brain barrier. Synonyms: ICI 204,448 hydrochloride; ICI204,448 hydrochloride; ICI-204,448 hydrochloride; (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride; (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 121264-04-8. Molecular formula: C23H27Cl3N2O4. Mole weight: 501.84. | |
| ICI 211965 | ICI 211965 is a selective 5-lipoxygenase inhibitor and it may be useful in regulating production of those interleukins involved in joint cartilage destruction. Synonyms: ICI 211965; ICI-211965; ICI211965; 1-(3-(Naphth-2-ylmethoxy)phenyl)-1-(thiazol-2-yl)propyl methyl ether. Grades: 98%. CAS No. 129424-08-4. Molecular formula: C24H23NO2S. Mole weight: 389.52. | |
| ICI 216140 | ICI 216140 is a GRP/bombesin receptor 2 antagonist with the IC 50 of 2 nM. ICI 216140 can reduce Bombesin (HY-P0195)-stimulated pancreatic amylase secretion and attenuates Bombesin (HY-P0195)-stimulated increases in blood pressure [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 124001-41-8. Pack Sizes: 1 mg. Product ID: HY-P3112. | |
| ICI 216140 | ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50 = 2 nM in vitro). Grades: ≥95%. CAS No. 124001-41-8. Molecular formula: C45H65N13O8. Mole weight: 916.1. | |
| ICI 63197 | ICI 63197. Group: Biochemicals. Grades: Purified. CAS No. 27277-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICI 63197 | ICI 63197 is a specific and potent cAMP phosphodiesterase IV (PDE 4) inhibitor. Its IC50 value is 35 nM for inhibition of [3H]-rolipram binding to rat brain. It is potent in anatagonizing reserpine-induced hypothermia. It has an antidepressant effect following systemic administration in vivo. Synonyms: ICI 63197; ICI63197; ICI-63197; 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one; 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimidin-5-one. Grades: ≥99% by HPLC. CAS No. 27277-00-5. Molecular formula: C9H13N5O. Mole weight: 207.23. | |
| ICI-63197 | ICI-63197 is a phosphodiesterase 3 (PDE3) and PDE4 inhibitor with K i values of 9 μM and 10 μM, respectively. ICI-63197 is selectivity against PDE1 and PDE2. ICI-63197 has antidepressant effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27277-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103024. | |
| ICI 89406 | ICI 89406 is a selective β-adrenergic antagonist. It is a low efficacy partial agonist and does not affect resting cardiac parameters. Synonyms: ICI 89406; ICI89406; ICI-89406; N-[2-[3-(2-Cyanophenoxy)-2-hydroxypropylamino]ethyl]-N'-phenylurea. Grades: ≥99% by HPLC. CAS No. 53671-71-9. Molecular formula: C19H22N4O3. Mole weight: 354.41. | |
| Icilin | Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 ( TRPM8 ) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner ( EC 50 =1.4 μM). Icilin is a "super-cooling agent" [1] [2]. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-3-5. CAS No. 36945-98-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-11062. | |
| Icilin | Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Synonyms: AG 3-5; AG3-5; AG-3-5; AG 3-5 cpd; 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one;3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone. Grades: ≥98%. CAS No. 36945-98-9. Molecular formula: C16H13N3O4. Mole weight: 311.29. | |
| Icilin | Icilin. Group: Biochemicals. Grades: Purified. CAS No. 36945-98-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Iclaprim | Cas No. 192314-93-5. | |
| Iclaprim | Iclaprim. Group: Biochemicals. Alternative Names: 5-[(2-Cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-2,4-pyrimidine-diamine. Grades: Highly Purified. CAS No. 192314-93-5. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C19H22N4O3. US Biological Life Sciences. | Worldwide |
| Iclaprim | Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus ( MRSA ) with an MIC 90 of 0.06 μg/mL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-100. CAS No. 192314-93-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101479. | |
| Iclepertin | Iclepertin (BI-425809) is a potent, selective and orally active glycine transporter 1 (GlyT1) inhibitor. Iclepertin is inactive against GlyT2. Iclepertin can be used for Alzheimer disease and schizophrenia research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI-425809. CAS No. 1421936-85-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138935. | |
| Iclepertin | Iclepertin, a glycine transporter inhibitor, is an antipsychotic drug. Synonyms: [5-(methanesulfonyl)-2-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(trifluoromethyl)-1,2-oxazol-3-yl]-3-azabicyclo[3.1.0]hexan-3-yl}methanone; (5-(methylsulfonyl)-2-(((R)-1,1,1-trifluoropropan-2-yl)oxy)phenyl)((1R,5R)-1-(5-(trifluoromethyl)isoxazol-3-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methanone. CAS No. 1421936-85-7. Molecular formula: C20H18F6N2O5S. Mole weight: 512.42. | |
| ICM0201 | It is originally isolated from Cunninghamella sp. F-1490. ICM0201 can inhibit the formation of osteoclasts in mouse bone marrow cells with IC50 of 0.78 μg/mL. Synonyms: ICM 0201; ICM-0201. Molecular formula: C12H13NO6. Mole weight: 267.23. | |
| ICMA | Dipole moment of indene-C60 monoadduct (ICMA) was estimated to be 2.34 debye. Film formation of ICMA under optimum conditions was studied.1 As a potential candidate for field effect transistors (FETs), ICMA exhibits unipolar n-channel characteristics and high electron mobility. Group: 3d printing materials carbon nano materials organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 1',4'-Dihydro-naphtho[2',3':1,2][5,6]fullerene-C60,C60 derivative, indene-C60 monoadduct. CAS No. 186682-36-0. Pack Sizes: 250 mg in glass insert. Molecular formula: 836.8. |  |
| ICMT Inhibitor (Cysmethynil) | An inhibitor of protein prenylation. Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt.A cell-permeable indole acetamide that acts as a substrate-competitive and AdoMet-noncompetitive Icmt...25uM) induces G1 cell cycle-arrest and autophagy-mediated, but not apoptotic, cell death in prostate cancer PC3 cells with concomitant PI 3-K/Akt and mTOR signaling blockage, consistent with inhibition of Icmt-mediated activation of Ras and Rheb GTPases. Murine PC3 xenograft studies reveal limited in vivo efficacy. Group: Biochemicals. Alternative Names: Cysmethynil; 2-(5-(3-Methylphenyl)-1-octyl-1H-indol-3-yl)acetamide, 2-(1-Octyl-5-m-tolyl-1H-indol-3-yl) acetamide; Isoprenylcysteine Carboxyl Methyltransferase Inhibitor). Grades: Highly Purified. CAS No. 851636-83-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C25H32N2O, Molecular Weight: 376.5. US Biological Life Sciences. | Worldwide |
| ICMT Inhibitor II, FTPAT ((E)-methyl-3-((5-(4-(2-((1,1-biphenyl]-4-yl)ethyl)-1H-1,2,3-triazol-1-yl)-3-methylpent-2-en-1-yl)thio)propanoate) | A cell-permeable triazolo-farnesylthiopropanoate compound that acts as a potent, reversible, and isoprenyl mimetic competitive inhibitor of isoprenylcysteine carboxyl methyltransferase activity (ICMT; IC50=800nM; Ki=400nM). Shown to prevent K-Ras membrane localization in GFP-K-Ras transfected Jurkat T-cells. Exhibits selective toxicity towards wt-Icmt+/+ mouse embryonic fibroblasts (MEFs) over Icmt-/- MEFs (IC50=33 and >100uM). Also shown to arrest the proliferation of PaTu-8902, a highly metastatic pancreatic cancer cells (IC50=8uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Icofungipen | Icofungipen, a cyclic β-amino acid, is the representative of a novel class of antifungals, active against Candida. Its in vivo efficacy indicates its potential for the oral treatment of yeast infections. Synonyms: (1R,2S)-2-amino-4-methylidenecyclopentane-1-carboxylic acid; Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI); Icofungipen; PLD 118; PLD118; PLD-118; BAY 10-8888; BAY 108888; BAY108888. Grades: 95%. CAS No. 198022-65-0. Molecular formula: C7H11NO2. Mole weight: 141.167. | |
| Icometasone | Cas No. 4647-20-5. | |
| Icomethasone | Icomethasone is a metabolite of Mometasone Furoate (M4425). Group: Biochemicals. Alternative Names: (11 β,16α)-9-Chloro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Icometasone. Grades: Highly Purified. CAS No. 4647-20-5. Pack Sizes: 10mg. Molecular Formula: C22H29ClO5, Molecular Weight: 408.92. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Acetate | Icomethasone 21-Acetate. Group: Biochemicals. Alternative Names: Icometasone-21-acetate; 9-Chloro-11 β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione; (11 β,16α)-21-(Acetyloxy)-9-chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 24916-91-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Acetate | Cas No. 24916-91-4. | |
| Icomethasone 21-Mesylate | Cas No. 352315-75-4. | |
| Icomethasone 21-Mesylate | Icomethasone 21-Mesylate is a derivative of Icomethasone, used in the preparation of Mometasone. Group: Biochemicals. Alternative Names: (11 β , 16α ) -9-Chloro-11, 17-dihydroxy-16-methyl-21-[ (methylsulfonyl) oxy]pregna-1, 4-diene-3, 20-dione. Grades: Highly Purified. CAS No. 352315-75-4. Pack Sizes: 10mg. Molecular Formula: C23H31ClO7S, Molecular Weight: 487.01. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Mesylate | Icomethasone 21-Mesylate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pregna-1,4-diene-3,20-dione, 9-chloro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]-, (11β,16α)-, Icomethasone 21-mesylate, 9-Chloro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl Methanesulfonate, Mometasone Furoate Imp. N (EP), (11β,16α)-9-Chloro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione. CAS No. 352315-75-4. Pack Sizes: 10MG. IUPAC Name: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] methanesulfonate. Molecular Formula: C23H31ClO7S. Mole Weight: 487.01. Catalog: APS352315754. SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC (=O)C=C[C@]4 (C)[C@@]3 (Cl)[C@@H] (O)C[C@]2 (C)[C@@]1 (O)C (=O)COS (=O) (=O)C. Format: Neat. Shipping: Room Temperature. |  |
| Icomidocholic acid | Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aramchol; C20-FABAC. CAS No. 246529-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19796. | |
| Icopezil maleate | The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: CP 118954-11; CP-118,954-11. UNII-1P15W0SPEN; Icopezil maleate [USAN]; Icopezil maleate (USAN); 145815-98-1; CHEMBL329012; CP 118954-11. Grades: 98%. CAS No. 145815-98-1. Molecular formula: C27H29N3O6. Mole weight: 491.54. | |
| Icosabutate | Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis [1]. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent hypertriglyceridemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253909-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121212. | |
| Icosan-7-ylbenzene | Icosan-7-ylbenzene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosane, 7-phenyl-, icosan-7-ylbenzene, Benzene, (1-hexyltetradecyl)-, 7-PHENYLEICOSANE, 2398-64-3, NSC219880, AC1L2928, NSC-219880. Product Category: Heterocyclic Organic Compound. CAS No. 2398-64-3. Molecular formula: C26H46. Mole weight: 358.643 g/mol. Purity: 0.96. IUPACName: icosan-7-ylbenzene. Density: 0.853g/cm³. Product ID: ACM2398643. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Icosanal | Synonyms: Icosanal;Eicosanal;2400-66-0;FWBUWJHWAKTPHI-UHFFFAOYSA-N;EINECS219-275-5;AI3-24217. Grades: 95%. CAS No. 2400-66-0. Molecular formula: C20H40O. Mole weight: 296.53. | |
| Icosanamide | Icosanamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Icosanamide, Eicosanamide, EINECS 257-152-8, CID3016647, 51360-63-5. Product Category: Heterocyclic Organic Compound. CAS No. 51360-63-5. Molecular formula: C20H41NO. Mole weight: 311.545640 [g/mol]. Purity: 0.96. IUPACName: icosanamide. Canonical SMILES: CCCCCCCCCCCCCCCCCCCC(=O)N. Density: 0.866g/cm³. ECNumber: 257-152-8. Product ID: ACM51360635. Alfa Chemistry ISO 9001:2015 Certified. | |
| Icosanamide | Icosanamide, a derivative of fatty acid, displays promise as a therapeutic agent for diverse inflammatory ailments. With its impressive anti-inflammatory attributes, the compound has garnered attention for handling autoimmune diseases and treating conditions such as rheumatoid arthritis. Its efficacy is well-documented in several clinical studies. Synonyms: Eicosanamide; Arachamide. CAS No. 51360-63-5. Molecular formula: C20H41NO. Mole weight: 311.554. | |
| Icosanenitrile | Icosanenitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosanenitrile, Eicosanonitrile, CID78358, 4616-73-3. Product Category: Heterocyclic Organic Compound. CAS No. 4616-73-3. Molecular formula: C20H39N. Mole weight: 293.53 g/mol. Purity: 0.96. IUPACName: icosanenitrile. Density: 0.833g/cm³. Product ID: ACM4616733. Alfa Chemistry ISO 9001:2015 Certified. | |
| icosanoyl-CoA 5-desaturase | The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids. Group: Enzymes. Synonyms: acyl-CoA Δ5-desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0972; icosanoyl-CoA 5-desaturase; EC 1.14.19.10; acyl-CoA Δ5-desaturase (ambiguous). Cat No: EXWM-0972. |  |
| Icotinib | Icotinib (BPI-2009) is a potent and specific EGFR inhibitor with an IC 50 of 5 nM; also inhibits mutant EGFR L858R , EGFR L858R/T790M , EGFR T790M and EGFR L861Q. Icotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPI-2009. CAS No. 610798-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15164A. | |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Synonyms: BPI-2009H. Grades: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42. | |
| Icotinib-D4 | Icotinib-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1567366-82-8. Molecular Formula: C22H17D4N3O4. Mole Weight: 395.45. Catalog: APB1567366828. | |
| Icotinib Hydrochloride | Icotinib Hydrochloride (BPI-2009) is a potent and specific EGFR inhibitor with an IC 50 of 5 nM; also inhibits mutant EGFR L858R , EGFR L858R/T790M , EGFR T790M and EGFR L861Q. Icotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPI-2009H. CAS No. 1204313-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15164. | |
| Icotinib Impurity 1 | Icotinib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1058651-74-3. Molecular Formula: C22H21N3O5. Mole Weight: 407.43. Catalog: APB1058651743. | |
| Icotinib Impurity 10 | Icotinib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2376901-56-1. Molecular Formula: C20H21N3O5. Mole Weight: 383.4. Catalog: APB2376901561. | |
| Icotinib Impurity 11 | Icotinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2305154-39-4. Molecular Formula: C17H12N4O2. Mole Weight: 304.31. Catalog: APB2305154394. | |
| Icotinib Impurity 12 | Icotinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 610798-26-0. Molecular Formula: C20H20ClN3O4. Mole Weight: 401.85. Catalog: APB610798260. | |
| Icotinib Impurity 13 | Icotinib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 610798-18-0. Molecular Formula: C20H20BrN3O4. Mole Weight: 446.3. Catalog: APB610798180. | |
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