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| Product | Description | |
|---|---|---|
| Icapamespib | Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ151 and radiolabeled PU-HZ151 showed selectivity for epichaperomes over the individual chaperome members. Icapamespib demonstrated the ability to productively engage the target in cells, mice, and humans. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Icapamespib; PU-HZ 151; PU-HZ-151; PU-HZ151; PUHZ 151; PUHZ-151; PUHZ151. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1000999-96-1. Molecular formula: C19H23IN6O2S. Mole weight: 526.4. Purity: >98%. IUPACName: 9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine. Canonical SMILES: NC1=C2N=C(SC3=C(I)C=C(OCO4)C4=C3)N(CCNCC(C)(C)C)C2=NC=N1. Product ID: ACM1000999961. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Icariin | 7-(β-D-Glucopyranosyloxy)-5-hydroxy-4-methoxy-8-(3-methylbut-2-en-1-yl)-3-(α-L-rhamnopyranosyloxy)flavone C33H40O15. CAS No. 489-32-7. Product ID: 8-05151. Mole weight: 676.67. Properties: Prenylated flavonol glycoside. |  |
| Icariin | Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66. Purity: 0.98. IUPACName: 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one. Canonical SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O. Density: 1.55 g/ml. Product ID: ACM489327. Alfa Chemistry ISO 9001:2015 Certified. | |
| Icariin | Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Synonyms: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-b-D-glucopyranosyloxy-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. Grade: ≥ 98%. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66. |  |
| Icariin | Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC 50 s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Uses: Scientific research. Group: Natural products. Alternative Names: Ieariline. CAS No. 489-32-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0014. |  |
| Icariin | Icariin - Product ID: NST-10-63. Category: Flavonoids. Purity: 98%. Test method: HPLC. CAS No. 489-32-7. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: Yellow Powder. Molecular formula: C33H40O15. Mole weight: 676.66. Storage: +2 +8 °C. |  |
| Icariin | Icariin. Group: Biochemicals. Grades: Plant Grade. CAS No. 489-32-7. Pack Sizes: 20mg. Molecular Formula: C33H40O15, Molecular Weight: 676.66. US Biological Life Sciences. |  Worldwide |
| Icariin-d6 | Icariin-d6 is a labelled Icariin, which is one of flavonoid isolated from the plant Horny Goat Weed. Grade: > 95%. Molecular formula: C33H34O15D6. Mole weight: 682.71. | |
| Icariside E5 | Icariside E5 is a lignan glycoside isolated from the herbs of Epimedium brevicornu. It has antioxidant property that strengthens the importance of peppers in the Mediterranean diet. Uses: Antioxidant property. Synonyms: 3-[4-β-D-Glucopyranosyloxy-5-methoxy-3-[2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethyl]phenyl]-2-propen-1-ol; 2-[(2R)-1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-propanyl]-4-[(1 E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl β-D-glucopyranoside. Grade: 93%. CAS No. 126176-79-2. Molecular formula: C26H34O11. Mole weight: 522.54. | |
| Icariside I | Icariside I. Group: Biochemicals. Grades: Plant Grade. CAS No. 56725-99-6. Pack Sizes: 10mg. Molecular Formula: C27H30O11, Molecular Weight: 530.52. US Biological Life Sciences. | Worldwide |
| Icariside I | Icariside I Inhibitor. Uses: Scientific use. Product Category: T3808. CAS No. 56725-99-6. |  |
| Icariside II | A regulator of CXCR4 expression. Uses: Ingredient of health care products. Synonyms: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Baohuoside 1; Baohuoside I; Baohuside I; Icariin II; Icariside II. Grade: 98%. CAS No. 113558-15-9. Molecular formula: C27H30O10. Mole weight: 514.52. | |
| Icaritin | Icaritin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 118525-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H20O6. US Biological Life Sciences. | Worldwide |
| Icaritin | Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornu Maxim. and potently inhibits proliferation of K562 cells ( IC 50 of 8 μM) and primary CML cells ( IC 50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [1] [2] [3. Uses: Scientific research. Group: Natural products. Alternative Names: Anhydroicaritin. CAS No. 118525-40-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0678. | |
| Icaritin | Icaritin - Product ID: NST-10-167. Category: Flavonoids. Purity: 98%. Test method: HPLC. CAS No. 118525-40-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White Powder. Molecular formula: C21H20O6. Mole weight: 368.38. Storage: +2 +8 °C. | |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti | |
| Icaritin (Anhydroicaritin) | Icaritin (Anhydroicaritin). Group: Biochemicals. Grades: Plant Grade. CAS No. 118525-40-9. Pack Sizes: 20mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences. | Worldwide |
| Icaritin Liposome (PEGylated) | Icaritin is a natural flavonoid compound that exhibits anticancer effects on various tumors, including hematologic malignancies such as leukemia, lymphoma, and multiple myeloma. This product is a pre-formulated liposome encapsulating Icaritin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| i-Carradecaitoldecasulfate decasodium salt | i-Carradecaitoldecasulfate decasodium salt is a groundbreaking biomedical compound which can inhibit designated enzymes responsible for exacerbating cancer cell proliferation. It aids in studying lung, breast and prostate malignancies. Molecular formula: C60H84O72S10Na10. Mole weight: 2507.82. | |
| i-Carrageenan | i-Carrageenan. CAS No. 9062-7-1. Product ID: 4-00549. Properties: sulfate content 30-40%, forms gels powder. | |
| i-Carrahexaitol hexasulfate hexasodium salt | i-Carrahexaitol hexasulfate hexasodium salt is a derivative derived from i-Carrahexaitol, offering unprecedented opportunities for studying a multitude of diseases and conditions such as drug-resistant cancers and inflammatory disorders. Synonyms: Iota-Carrahexaitol-Hexasulfate Hexasodium Salt. Molecular formula: C36H52O44S6Na6. Mole weight: 1519.11. | |
| i-Carrahexaose hexasulfate hexasodium salt | i-Carrahexaose hexasulfate hexasodium salt, an innovative biomedical substance, stands as a formidable solution against an array of ailments. By virtue of its unrivaled chemical configuration, it exhibits an outstanding capacity to impede the replication of notorious infectious agents such as HIV, influenza, and herpes viruses. Moreover, this extraordinary therapeutic treasure finds application in tackling inflammatory disorders and combating cancer. Synonyms: Iota-Carrahexaose-Hexasulfate Hexasodium Salt. Molecular formula: C36H50O43S6Na6. Mole weight: 1501.09. | |
| i-Carraoctaitol octasulfate octasodium salt | i-Carraoctaitol octasulfate octasodium salt, an eminent biomedicine product, distinguishes itself as a paramount entity employed in the amelioration of diverse maladies. Exhibiting efficacy across ailments such as cancer, cardiovascular disorders, and inflammatory diseases, this multifaceted compound assumes the role of a commendable therapeutic intervention. Synonyms: Iota-Carraoctaitol 12,24,32,44,52,64,72,84-octasulfate octasodium salt; Iota-Carraoctaitol-Octasulfate Octasodium Salt. Molecular formula: C48H68O58S8Na8. Mole weight: 2013.46. | |
| i-Carratetraitol tetrasulfate tetrasodium salt | i-Carratetraitol tetrasulfate tetrasodium salt is an extraordinary pharmaceutical compound extensively employed in the biomedical sphere. This exceptional substance showcases unparalleled efficiency in studying enduring inflammatory ailments, such as arthritand asthma. Synonyms: Iota-Carratetraitol-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H36O30S4Na4. Mole weight: 1024.75. | |
| i-Carratetraose tetrasulfate tetrasodium salt | i-Carratetraose tetrasulfate tetrasodium salt is a potent biomedical compound used in the treatment of various inflammatory conditions and autoimmune diseases. It exhibits excellent anti-inflammatory properties by effectively inhibiting the activation of pro-inflammatory cytokines. This product acts as a therapeutic agent to alleviate symptoms associated with conditions such as rheumatoid arthritis and Crohn's disease while promoting immune modulation. Synonyms: Iota-Carratetraose-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H34O29S4Na4. Mole weight: 1006.73. | |
| Icatibant | Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC 50 and K i of 1.07 nM and 0.798 nM respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: HOE 140. CAS No. 130308-48-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-17446. | |
| Icatibant | Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-; H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; HOE140; HOE 140; HOE-140. Grade: >98%. CAS No. 130308-48-4. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| Icatibant acetate | Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC 50 and K i of 1.07 nM and 0.798 nM respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: HOE 140 acetate. CAS No. 138614-30-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108896. | |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grade: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
| Icatibant Acetate | Icatibant Acetate. Categories: icatibant acetate; hoe-140. |  CA, FL & NJ |
| ICBA | ICBA is a C60 derivative that can be synthesized from C60 and indene. It is an acceptor material with shallow lowest occupied molecular orbital(LUMO) which can be used to enhance the performance of polymeric solar cells(PSCs). Uses: Icba can be used with poly(3-hexylthiophene)(p3ht) as an active layer which can be used in the fabrication of organic solar cells(oscs).icba in combination with thiazolo-thiazolo can be used as a donor. it can be blended with pcbm for photovoltaic based application. Group: 3d printing materials carbon nano materials dye-sensitized solar cell (dssc) materials electronic materials organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 1', 1'', 4', 4''-Tetrahydro-di[1, 4]methanonaphthaleno[1, 2:2', 3', 56, 60:2'', 3''][5, 6]fullerene-C60, C60 derivative, indene-C60 bisadduct. CAS No. 1207461-57-1. Pack Sizes: 250 mg in glass insert. Molecular formula: 952.99. Mole weight: C78H16. C1C2C3= CC= CC= C3C1C45C26C7= C8C9= C1C2= C3C% 10= C9C9= C% 11C% 12= C% 10C% 10= C% 13C% 14= C% 12C% 12= C% 15C% 16= C (C4= C4C% 17= C% 16C% 16= C% 18C% 19= C% 17C% 17= C% 20C% 21= C% 19C% 19= C% 22C% 23= C% 21C% 21= C (C1= C7C (= C% 21% 20) C6= C% 174) C2= C% 23C (= C3% 10) C% 221C% 13 (C2CC1C1= CC= CC= C21) C (= C% 18% 19) C% 14= C% 15% 16) C (= C% 12% 11) C5= C98. InChI=1S/C78H16/c1-2-6-12-11 (5-1) 15-9-16 (12) 76-69-53-37-23-25-41-29 (37) 30-38-24-26-42 (30) 58-57 (41) 73-65-49 ( |  |
| I-CBP112 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| I-CBP 112 | I-CBP112 has been found to be a CBP/p300 bromodomain inhibitor and could reduce the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells. Synonyms: I-CBP112; I-CBP-112; I-CBP 112. 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one. Grade: ≥98% by HPLC. CAS No. 1640282-31-0. Molecular formula: C27H36N2O5. Mole weight: 468.59. | |
| I-CBP112 hydrochloride | I-CBP112 is a selective inhibitor of CBP and EP300 bromodomain (Kds = 0.142 and 0.625 μM, respectively). CBP and EP300 are histone acetyltransferase (HAT) enzymes that serve as transcriptional coactivators and have been found to be dysregulated in cancer and other diseases. Synonyms: 1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one hydrochloride. Grade: ≥90%. CAS No. 2147701-33-3. Molecular formula: C27H36N2O5·HCl. Mole weight: 505.1. | |
| ICCB-19 hydrochloride | ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD). ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). Synonyms: N-cycloheptyl-2-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)acetamide hydrochloride. CAS No. 1803605-68-6. Molecular formula: C12H22ClN3OS. Mole weight: 291.84. | |
| ICCB-19 hydrochloride | ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1803605-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138779. | |
| ICCB280 | ICCB280 is a potent inducer of C/EBPα. ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPα and affecting its downstream targets (such as C/EBPε, G-CSFR and c-Myc). Synonyms: (E)-2-(3,4-Dihydroxystyryl)-3-(2-methoxyphenyl)quinazolin-4(3H)-one. Grade: 98%. CAS No. 2041072-41-5. Molecular formula: C23H18N2O4. Mole weight: 386.40. | |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Synonyms: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52. | |
| Icenticaftor | Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC 50 s of 79 nM and 497 nM for F508del and G551D CFTR , respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QBW251. CAS No. 1334546-77-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109177. | |
| Icenticaftor | Icenticaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which can be used for the treatment of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Synonyms: NVP-QBW251; QBW251. CAS No. 1334546-77-8. Molecular formula: C12H13F6N3O3. Mole weight: 361.24. | |
| Icerguastat | Icerguastat (Sephin1), a derivative of Guanabenz lacking the ?2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2? dephosphorylation, thereby prolonging the protective response. Anti-prion effect[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sephin1; IFB-088. CAS No. 951441-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111022. | |
| ICG001 | ICG001 Inhibitor. Uses: Scientific use. Product Category: T2237. CAS No. 847591-62-2. | |
| ICG-001 | ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and binds to cyclic AMP responsive element binding-binding protein (CBP)-mediated transcription with IC50 value of 3 μM. ICG-001 has been demonstrated to inhibit gastric cancer cell growth and reduce chemoresistance of cancer stem cell-like population. Synonyms: ICG 001; (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide. Grade: >98%. CAS No. 780757-88-2. Molecular formula: C33H32N4O4. Mole weight: 548.63. | |
| ICG-001 | ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC 50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 780757-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14428. | |
| ICG-DBCO | ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W588722. | |
| ICG Maleimide | ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm). Uses: Scientific research. Group: Fluorescent dye. CAS No. 2143933-81-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1744. | |
| ICG-OSu | ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: ICG NHS ester. CAS No. 1622335-40-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1041. | |
| I-Cholestane | I-Cholestane. Synonyms: i-Cholestane; 3,5-Cyclocholestane; (3aR,3bS,5aR,6R,8aS,8bS)-3a,5a-dimethyl-6-((R)-6-methylheptan-2-yl)hexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalene; (3α,5α)-3,5-Cyclocholestane. CAS No. 465-56-5. Molecular formula: C27H46. Mole weight: 370.65. | |
| i-Cholesteryl methyl ether | ~95%. Group: Fluorescence/luminescence spectroscopy. | |
| Ichthammol | Ichthammol is an antibacterial, fungicidal, antiinflammatory agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 8029-68-3. Pack Sizes: 100g, 250g. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences. | Worldwide |
| Ichthammol USP | Ichthammol USP. | CA, FL & NJ |
| ICI-118551 HCl | A highly selective antagonist for the β2 adrenergic receptors. Binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively). Synonyms: ICI-118551; ICI118551; ICI 118551; ICI-118,551; ICI118,551; ICI 118,551. Grade: 98%. CAS No. 72795-19-8. Molecular formula: C17H28ClNO2. Mole weight: 313.866. | |
| ICI 118,551 hydrochloride | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| ICI 118551 hydrochloride | ICI 118551 hydrochloride is a highly selective β2 adrenergic antagonist (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively), inhibited cAMP accumulation by 50% (IC50 = 1.5 microM and 1.7 microM, respectively). Uses: A highly selective β2 adrenergic receptor antagonist. Synonyms: ICI 118551 hydrochloride; ICI118551 hydrochloride; ICI-118551 hydrochloride; (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride; (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol; hydrochloride. Grade: ≥98%. CAS No. 72795-01-8. Molecular formula: C17H27NO2.HCl. Mole weight: 313.86. | |
| ICI 118551 Hydrochloride ((±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol Hydrochloride) | A highly selective antagonist for the beta-2 adrenergic receptors. Binds to the beta-2 subtype with at least 100 times greater affinity than beta-1 or beta-3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257nM for beta-2, beta-1 and beta-3 receptors respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 72795-19-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ICI141292 | ICI141292, also known as Epanolol, is a adrenergic β-antagonist with a greater affinity for β1- than β2-adrenoceptors, which is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. Synonyms: N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide; epanolol; ICI 141,292; ICI 141292; ICI-141,292; N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxyphenylacetamide; Visacor. CAS No. 86880-51-5. Molecular formula: C20H23N3O4. Mole weight: 369.41. | |
| ICI 154,129 | ICI 154,129 is a selective δ opioid antagonist. It is a peptide analog that antagonized the effects of Leu-enkephalin. Uses: Narcotic antagonists. Synonyms: N,N-Di(2-propenyl)-L-Tyr-N-[2-[[(S)-2-[[(S)-1-carboxy-3-methylbutyl]amino]-2-oxo-1-benzylethyl]thio]ethyl]-Gly-NH2; M-154129. Grade: >98%. CAS No. 83420-94-4. Molecular formula: C34H46N4O6S. Mole weight: 638.83. | |
| ICI 162,846 | ICI 162,846 is a potent histamine H2 receptor antagonist. Synonyms: ICI 162,846; ICI162,846; ICI-162,846; N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine; 3-[[Imino[(2,2,2-trifluoroethyl)amino]methyl]amino]-1H-pyrazole-1-pentanamide. CAS No. 84545-30-2. Molecular formula: C11H17F3N6O. Mole weight: 306.29. | |
| ICI 174864 | ICI 174864 is a highly selective, potent δ-receptor antagonist. ICI 174864 is equipotent with naloxone and can not reverse the effect of the μ-agonist [D-Ala2, MePhe4, Gly-Ol5]enkephalin or the κ-agonist-tifluadom [1]. Uses: Scientific research. Group: Peptides. CAS No. 89352-67-0. Pack Sizes: 1 mg. Product ID: HY-101230. | |
| ICI 174,864 | ICI 174,864 is a potent and highly selective δ opioid antagonist. It shows partial agonist in vitro activity at δ receptors at high concentrations. Synonyms: ICI 174,864; ICI174,864; ICI-174,864; N,N-Di-2-propen-1-yl-L-tyrosyl-2-methylalanyl-L-phenylalanyl-L-leucine; NIH 10893; N,N-diallyl-tyrosyl-alpha-aminoisobutyric acid-phenylalanyl-leucine; L-Leucine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-L-phenylalanyl)-; N,N-Diallyl-Tyr-aib-Phe-Leu. Grade: >98%. CAS No. 89352-67-0. Molecular formula: C38H53N5O7. Mole weight: 691.87. | |
| ICI 185,282 | ICI 185,282 is a potent thromboxane receptor antagonist. Synonyms: ICI-185282; ICI 185282; ICI185282; 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid. CAS No. 106393-80-0. Molecular formula: C18H21F3O5. Mole weight: 374.36. | |
| ICI 192605 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ICI 192,605 | ICI 192,605 is a potent thromboxane A2 receptor antagonist. It can reverse vasoconstriction induced by inhibition of NO production and inhibits platelet aggregation, which leads to an increase in TXA2 release. It also inhibits contractile responses to U 46619. Synonyms: ICI 192605 ; ICI192605; ICI-192605. (4Z)-rel-, 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid; 4-Hexenoic acid, 6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-; 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoic acid; (E)-6-[(2S,4S,5R)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic Acid. Grade: ≥98% by HPLC. CAS No. 117621-64-4. Molecular formula: C22H23ClO5. Mole weight: 402.87. | |
| ICI-198615 | ICI-198615 is a novel, potent and selective peptide leukotriene antagonist. It may be useful for the the treatment of allergic diseases. Uses: Ici-198615 may be useful for the the treatment of allergic diseases. Synonyms: [1-[[2-Methoxy-4-[[(phenylsulfonyl)amino]carbonyl]phenyl]methyl]-1H-indazol-6-yl]carbamic acid cyclopentyl ester; Cyclopentyl N-[1-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]indazol-6-yl]carbamate; ICI 198615; ICI-198615; ICI198615; ICI-198,615; ZM 198615; ZM-198615. Grade: >98 %. CAS No. 104448-53-5. Molecular formula: C28H28N4O6S. Mole weight: 548.61. | |
| ICI 199441 | ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 115199-84-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101205. | |
| ICI 199,441 hydrochloride | ICI 199,441 hydrochloride is the hydrochloride salt of ICI 199,441, which is a selective and highly potent κ agonist. It is 146-fold more active than U-50488 in vitro. It has a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. It has analgesic properties. Synonyms: ICI 199,441 hydrochloride; ICI199,441 hydrochloride; ICI-199,441 hydrochloride; 3,4-Dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; (S)-3,4-Dichloro-N-methyl-N-[1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 115199-84-3. Molecular formula: C21H25Cl3N2O. Mole weight: 427.80. | |
| ICI-204448 | ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121264-04-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101231. | |
| ICI 204,448 hydrochloride | ICI 204,448 hydrochloride is the hydrochloride salt of ICI 204,448, which is a peripherally acting κ opioid receptor agonist. It does not cross the blood-brain barrier. Synonyms: ICI 204,448 hydrochloride; ICI204,448 hydrochloride; ICI-204,448 hydrochloride; (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride; (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 121264-04-8. Molecular formula: C23H27Cl3N2O4. Mole weight: 501.84. | |
| ICI 204,448 hydrochloride | solid. Group: Fluorescence/luminescence spectroscopy. | |
| ICI 211965 | ICI 211965 is a selective 5-lipoxygenase inhibitor and it may be useful in regulating production of those interleukins involved in joint cartilage destruction. Synonyms: ICI 211965; ICI-211965; ICI211965; 1-(3-(Naphth-2-ylmethoxy)phenyl)-1-(thiazol-2-yl)propyl methyl ether. Grade: 98%. CAS No. 129424-08-4. Molecular formula: C24H23NO2S. Mole weight: 389.52. | |
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