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| Product | Description | |
|---|---|---|
| ICMT-IN-8 | ICMT-IN-8 is an inhibitor of ICMT (IC50=0.652 μM). CAS No. 1313602-76-4. Molecular formula: C23H31NO3. Mole weight: 369.50. |  |
| ICMT-IN-9 | ICMT-IN-9 is an inhibitor of ICMT (IC50=0.16 μM). CAS No. 1313602-93-5. Molecular formula: C22H28FNO2. Mole weight: 357.46. | |
| ICMT Inhibitor (Cysmethynil) | An inhibitor of protein prenylation. Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt.A cell-permeable indole acetamide that acts as a substrate-competitive and AdoMet-noncompetitive Icmt...25uM) induces G1 cell cycle-arrest and autophagy-mediated, but not apoptotic, cell death in prostate cancer PC3 cells with concomitant PI 3-K/Akt and mTOR signaling blockage, consistent with inhibition of Icmt-mediated activation of Ras and Rheb GTPases. Murine PC3 xenograft studies reveal limited in vivo efficacy. Group: Biochemicals. Alternative Names: Cysmethynil; 2-(5-(3-Methylphenyl)-1-octyl-1H-indol-3-yl)acetamide, 2-(1-Octyl-5-m-tolyl-1H-indol-3-yl) acetamide; Isoprenylcysteine Carboxyl Methyltransferase Inhibitor). Grades: Highly Purified. CAS No. 851636-83-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C25H32N2O, Molecular Weight: 376.5. US Biological Life Sciences. |  Worldwide |
| ICMT Inhibitor II, FTPAT ((E)-methyl-3-((5-(4-(2-((1,1-biphenyl]-4-yl)ethyl)-1H-1,2,3-triazol-1-yl)-3-methylpent-2-en-1-yl)thio)propanoate) | A cell-permeable triazolo-farnesylthiopropanoate compound that acts as a potent, reversible, and isoprenyl mimetic competitive inhibitor of isoprenylcysteine carboxyl methyltransferase activity (ICMT; IC50=800nM; Ki=400nM). Shown to prevent K-Ras membrane localization in GFP-K-Ras transfected Jurkat T-cells. Exhibits selective toxicity towards wt-Icmt+/+ mouse embryonic fibroblasts (MEFs) over Icmt-/- MEFs (IC50=33 and >100uM). Also shown to arrest the proliferation of PaTu-8902, a highly metastatic pancreatic cancer cells (IC50=8uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Icofungipen | Icofungipen, a cyclic β-amino acid, is the representative of a novel class of antifungals, active against Candida. Its in vivo efficacy indicates its potential for the oral treatment of yeast infections. Synonyms: (1R,2S)-2-amino-4-methylidenecyclopentane-1-carboxylic acid; Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI); Icofungipen; PLD 118; PLD118; PLD-118; BAY 10-8888; BAY 108888; BAY108888. Grade: 95%. CAS No. 198022-65-0. Molecular formula: C7H11NO2. Mole weight: 141.167. | |
| Icomethasone | Icomethasone is a metabolite of Mometasone Furoate (M4425). Group: Biochemicals. Alternative Names: (11 β,16α)-9-Chloro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Icometasone. Grades: Highly Purified. CAS No. 4647-20-5. Pack Sizes: 10mg. Molecular Formula: C22H29ClO5, Molecular Weight: 408.92. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Acetate | Icomethasone 21-Acetate. Group: Biochemicals. Alternative Names: Icometasone-21-acetate; 9-Chloro-11 β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione; (11 β,16α)-21-(Acetyloxy)-9-chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 24916-91-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Mesylate | Icomethasone 21-Mesylate is a derivative of Icomethasone, used in the preparation of Mometasone. Group: Biochemicals. Alternative Names: (11 β , 16α ) -9-Chloro-11, 17-dihydroxy-16-methyl-21-[ (methylsulfonyl) oxy]pregna-1, 4-diene-3, 20-dione. Grades: Highly Purified. CAS No. 352315-75-4. Pack Sizes: 10mg. Molecular Formula: C23H31ClO7S, Molecular Weight: 487.01. US Biological Life Sciences. | Worldwide |
| Icomethasone 21-Mesylate | Icomethasone 21-Mesylate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pregna-1,4-diene-3,20-dione, 9-chloro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]-, (11?,16?)-, Icomethasone 21-mesylate, 9-Chloro-11?,17-dihydroxy-16?-methyl-3,20-dioxopregna-1,4-dien-21-yl Methanesulfonate, Mometasone Furoate Imp. N (EP), (11?,16?)-9-Chloro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione. CAS No. 352315-75-4. Pack Sizes: 10MG. IUPAC Name: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] methanesulfonate. Molecular formula: C23H31ClO7S. Mole weight: 487.01. Catalog: APS352315754. SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COS(=O)(=O)C. Format: Neat. Shipping: Room Temperature. |  |
| Icomethasone 21-Propionate | An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Synonyms: 9-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Propionate. CAS No. 107085-37-0. Molecular formula: C25H33ClO6. Mole weight: 464.98. | |
| Icomidocholic acid | Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aramchol; C20-FABAC. CAS No. 246529-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19796. |  |
| Icopezil maleate | The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: CP 118954-11; CP-118,954-11. UNII-1P15W0SPEN; Icopezil maleate [USAN]; Icopezil maleate (USAN); 145815-98-1; CHEMBL329012; CP 118954-11. Grade: 98%. CAS No. 145815-98-1. Molecular formula: C27H29N3O6. Mole weight: 491.54. | |
| Icosabutate | Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis [1]. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent hypertriglyceridemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253909-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121212. | |
| Icosan-7-ylbenzene | Icosan-7-ylbenzene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosane, 7-phenyl-, icosan-7-ylbenzene, Benzene, (1-hexyltetradecyl)-, 7-PHENYLEICOSANE, 2398-64-3, NSC219880, AC1L2928, NSC-219880. Product Category: Heterocyclic Organic Compound. CAS No. 2398-64-3. Molecular formula: C26H46. Mole weight: 358.643 g/mol. Purity: 0.96. IUPACName: icosan-7-ylbenzene. Density: 0.853g/cm³. Product ID: ACM2398643. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Icosanamide | Icosanamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Icosanamide, Eicosanamide, EINECS 257-152-8, CID3016647, 51360-63-5. Product Category: Heterocyclic Organic Compound. CAS No. 51360-63-5. Molecular formula: C20H41NO. Mole weight: 311.545640 [g/mol]. Purity: 0.96. IUPACName: icosanamide. Canonical SMILES: CCCCCCCCCCCCCCCCCCCC(=O)N. Density: 0.866g/cm³. ECNumber: 257-152-8. Product ID: ACM51360635. Alfa Chemistry ISO 9001:2015 Certified. | |
| Icosanenitrile | Icosanenitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eicosanenitrile, Eicosanonitrile, CID78358, 4616-73-3. Product Category: Heterocyclic Organic Compound. CAS No. 4616-73-3. Molecular formula: C20H39N. Mole weight: 293.53 g/mol. Purity: 0.96. IUPACName: icosanenitrile. Density: 0.833g/cm³. Product ID: ACM4616733. Alfa Chemistry ISO 9001:2015 Certified. | |
| icosanoyl-CoA 5-desaturase | The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids. Group: Enzymes. Synonyms: acyl-CoA Δ5-desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0972; icosanoyl-CoA 5-desaturase; EC 1.14.19.10; acyl-CoA Δ5-desaturase (ambiguous). Cat No: EXWM-0972. |  |
| ICOSLG/B7-H2/CD275 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Icotinib | Icotinib (BPI-2009) is a potent and specific EGFR inhibitor with an IC 50 of 5 nM; also inhibits mutant EGFR L858R , EGFR L858R/T790M , EGFR T790M and EGFR L861Q. Icotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPI-2009. CAS No. 610798-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15164A. | |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Synonyms: BPI-2009H. Grade: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42. | |
| Icotinib hydrochloride | Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Synonyms: Icotinib HCl; BPI-2009; BPI 2009; BPI2009. Grade: >98%. CAS No. 1204313-51-8. Molecular formula: C22H22ClN3O4. Mole weight: 427.88. | |
| Icotinib Hydrochloride | Icotinib Hydrochloride (BPI-2009) is a potent and specific EGFR inhibitor with an IC 50 of 5 nM; also inhibits mutant EGFR L858R , EGFR L858R/T790M , EGFR T790M and EGFR L861Q. Icotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPI-2009H. CAS No. 1204313-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15164. | |
| Icotinib Impurity 1 | Icotinib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1058651-74-3. Molecular formula: C22H21N3O5. Mole weight: 407.43. Catalog: APB1058651743. | |
| Icotinib Impurity 18 | Icotinib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1318600-04-2. Molecular formula: C22H23N3O6. Mole weight: 425.44. Catalog: APB1318600042. | |
| Icotinib Impurity 19 | Icotinib Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1318600-10-0. Molecular formula: C22H25N3O6. Mole weight: 427.46. Catalog: APB1318600100. | |
| Icotinib Impurity 20 | Icotinib Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1318600-06-4. Molecular formula: C22H23N3O6. Mole weight: 425.44. Catalog: APB1318600064. | |
| Icotinib Impurity 4 | Icotinib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1058651-82-3. Molecular formula: C28H29N3O11. Mole weight: 583.55. Catalog: APB1058651823. | |
| Icotinib Impurity 8 | Icotinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153437-34-4. Molecular formula: C17H15N3O2. Mole weight: 293.33. Catalog: APB153437344. | |
| Icotrokinra | Icotrokinra (JNJ-77242113) is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-? production in NK cells with an IC50 of 18.4 pM. In addition, Icotrokinra exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra can be used in the study of psoriasis, psoriatic arthritis, and inflammatory bowel disease[1]. Uses: Scientific research. Group: Peptides. Alternative Names: JNJ-77242113; JNJ-2113; PN-235. CAS No. 2763602-16-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10587. | |
| ICP-MS Internal Standard: Ge @ 100 ug/mL in 2% HNO3 | ICP-MS Internal Standard: Ge @ 100 ug/mL in 2% HNO3. Uses: For analytical and research use. Group: Aqueous inorganic; aqueous inorganic. Alternative Names: Ge. CAS No. 7440-56-4. Pack Sizes: 100ML. IUPAC Name: germanium. Molecular formula: Ge. Mole weight: 72.64. Catalog: APS7440564E. SMILES: [Ge]. Format: Single Solution. Shipping: Room Temperature. | |
| ICRF-193 | ICRF-193 is an TopoII inhibitor. (S,S)- and (R,R)-isomers ICRF-193 make up an racemic mixture, ICRF-196 (HY-118590A). ICRF-196 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21416-88-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118590. | |
| ICRF-193 | apoptosis inducer, arabinosidase substrate. Group: Fluorescence/luminescence spectroscopy. | |
| icrocaptide | icrocaptide. Synonyms: Icrocaptide. CAS No. 169543-49-1. Molecular formula: C21H40N8O5. | |
| iCRT14 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of ?-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase. Uses: Scientific research. Group: Signaling pathways. CAS No. 677331-12-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16665. | |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Synonyms: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. Grade: >98%. CAS No. 677331-12-3. Molecular formula: C21H17N3O2S. Mole weight: 375.44. | |
| iCRT 14 | iCRT 14. Group: Biochemicals. Grades: Purified. CAS No. 677331-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| iCRT-14 | A potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between β-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Group: Biochemicals. Alternative Names: 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione; iCRT 14; iCRT14. Grades: Highly Purified. CAS No. 677331-12-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| iCRT3 | iCRT3 is an inhibitor of both Wnt and ?-catenin-responsive transcription. Uses: Scientific research. Group: Signaling pathways. CAS No. 901751-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103705. | |
| iCRT5 | iCRT5 is a Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor (IC50 value of 18 nM for Wnt responsive STF16 luciferase). iCRT5 disrupts the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin. Synonyms: iCRT5; iCRT-5; iCRT 5; 4-[5-(3,4-Dimethoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-butyric acid; 4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid; EN300-00774; AC1Q49FJ. Grade: 99%. CAS No. 18623-44-4. Molecular formula: C16H17NO5S2. Mole weight: 367.44. | |
| Icrucumab | Icrucumab is a human monoclonal antibody directed against vascular endothelial growth factor receptor-1 (VEGFR-1). Icrucumab inhibits ligand-dependent phosphorylation of VEGFR-1 and downstream signaling, making icrucumab an attractive candidate for antitumor activity. Synonyms: IMC-18F1. Grade: 95%. CAS No. 1024603-92-6. Molecular formula: C6514H10024N1756O2032S42. Mole weight: 146.8 kDa. | |
| Icrucumab | Icrucumab (Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1) is a human Anti-VEGFR-1 IgG1 monoclonal antibody. Icrucumab has the potential for the research of advanced solid tumors[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1. CAS No. 1024603-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99364. | |
| ID-11014A | ID-11014A is a potent and selective agonist of GPR40 (free fatty acid receptor 1) that can increase insulin secretion and reduce glucose levels. Studies shows that it has a lower liver toxicity than TAK-785 and an improved glucose tolerance. Uses: The potential treatment of diabetes. Synonyms: ID 11014A. | |
| ID45 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ID 8 | ID 8. Group: Biochemicals. Grades: Purified. CAS No. 147591-46-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ID-8 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ID-8 | ID-8. Group: Biochemicals. Alternative Names: ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838. Grades: Highly Purified. CAS No. 147591-46-6. Pack Sizes: 25mg. Molecular Formula: C16 H14 N2O4, Molecular Weight: 298.3. US Biological Life Sciences. | Worldwide |
| ID-8 | ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture. Synonyms: ID-8; ID 8; ID8. Grade: >98%. CAS No. 147591-46-6. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| ID-8 | ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK). ID-8 sustains embryonic stem cell (ESC) self-renewal and pluripotency. ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147591-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15838. | |
| IDA | IDA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl3,5-diformyl-1-indolizinecarboxylate. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 163556-04-5. Molecular formula: C12H9NO4. Mole weight: 231.2. Purity: 90%+. IUPACName: Methyl3,5-diformylindolizine-1-carboxylate. Canonical SMILES: COC(=O)C1=C2C=CC=C(N2C(=C1)C=O)C=O. Product ID: ACM163556045-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| Idaein chloride | analytical standard. Group: Herbal medicinal products standards. | |
| Idalopirdine hydrochloride | Idalopirdine hydrochloride (Lu AE58054 hydrochloride) is a potent, selective 5-HT6 receptor antagonist with a K i value of 0.83 nM. Idalopirdine hydrochloride may be used in studies of Alzheimer's disease and schizophrenia, among other related disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AE58054 hydrochloride. CAS No. 467458-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14338A. | |
| Idarubicin | Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Synonyms: IMI30; IMI-30; IMI 30; NSC256439; NSC-256439; NSC 256439; 4-DMDR; IDA; 4-Demethoxydaunomycin; (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 4-Demethoxydaunorubicin; Idarubicine; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-92-9. Molecular formula: C26H27NO9. Mole weight: 497.50. | |
| Idarubicin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Idarubicin-13C, d3 | Idarubicin-13C, d3 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C25H24NO9[13C]D3. Mole weight: 501.51. | |
| Idarubicin-d3. Readily exchangeable deuterium labels in protic solvents | Labelled Idarubicin, an orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug, 1mg. Molecular Formula: C26H24D3NO9. US Biological Life Sciences. | Worldwide |
| Idarubicin-d4 | Idarubicin-d4 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C26H23NO9D4. Mole weight: 501.53. | |
| Idarubicin Dioxolane Hydrochloride | Idarubicin Dioxolane Hydrochloride is a possible impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: (7S,9S)-7-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-9-(2-methyl-1,3-dioxolan-2-yl)-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride. Molecular formula: C28H31NO10.HCl. Mole weight: 578.01. | |
| Idarubicin hydrochloride | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Idarubicin hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-25mg. Molecular Weight 497.49. See USA prepack pricing. |  |
| Idarubicin hydrochloride | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-10mg. Molecular Weight 497.49. See USA prepack pricing. | |
| Idarubicin hydrochloride | Idarubicin hydrochloride is an anthracycline antileukemic agent. It inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin hydrochloride inhibits the growth of bacteria and yeasts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin hydrochloride. CAS No. 57852-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381. | |
| Idarubicin Hydrochloride | Orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Alternative Names: (7S,9S)-Hydrochloride; Idamycin; NSC 256439; Zavedos. Grades: Highly Purified. CAS No. 57852-57-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Idarubicin Hydrochloride | Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Uses: Antibiotics, antineoplastic. Synonyms: (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione Hydrochloride; 4-DMD HCl; 4-Demethoxydaunorubicin Hydrochloride; Idamycin; NSC 256439; Zavedos; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: >98%. CAS No. 57852-57-0. Molecular formula: C26H28ClNO9. Mole weight: 533.95. | |
| Idarubicin Impurity 2 | Idarubicin Impurity 2 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Molecular formula: C28H31NO10. Mole weight: 541.55. | |
| Idarubicin Impurity 4 | Idarubicin Impurity 4 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,12-dihydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,9-dihydroxy-7-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (7S-cis)-. CAS No. 85440-44-4. Molecular formula: C28H26F3NO9. Mole weight: 577.51. | |
| Idarubicin Isomer | Idarubicin Isomer is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-; 4-Demethoxydaunorubicin, beta; 4-Demethoxy-7,9-di-epi-daunorubicin, beta; 7-O-β-Daunosaminyl-4-demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-93-0. Molecular formula: C26H27NO9. Mole weight: 497.49. | |
| Idarubicin Isomer hydrochloride | Idarubicin Isomer hydrochloride is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (7S,9S)-9-Acetyl-7-(((2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Idarubicin Impurity 6; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside hydrochloride; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-, hydrochloride (1:1); 7-O-β-Daunosaminyl-4-demethoxydaunomycinone hydrochloride; Daunomycinone, 7-O-β-daunosaminyl-4-demethoxy-, hydrochloride. CAS No. 60660-72-2. Molecular formula: C26H27NO9.HCl. Mole weight: 533.96. | |
| Idarubicinol | Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grade: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52. | |
| Idarubicinol-13C, d3 | Idarubicinol-13C, d3 is a labelled nalogue of Idarubicinol. Grade: > 95%. Molecular formula: C26H26NO9D3. Mole weight: 503.53. | |
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