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Ilaprazole (IY-81149) sodium is an orally active proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H + /K + -ATPase in a dose-dependent manner with an IC 50 of 6 μM in rabbit parietal cell preparation. Ilaprazole sodium is used for the research of gastric ulcers. Ilaprazole sodium is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IY-81149 sodium. CAS No. 172152-50-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2145.
Ilaprazole sodium hydrate
Ilaprazole (IY-81149) sodium hydrate is an orally active proton pump inhibitor. Ilaprazole sodium hydrate irreversibly inhibits H + /K + -ATPase in a dose-dependent manner with an IC 50 of 6 μM in rabbit parietal cell preparation. Ilaprazole sodium hydrate is used for the research of gastric ulcers. Ilaprazole sodium hydrate is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IY-81149 sodium hydrate. CAS No. 2322264-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2145A.
Ile-Gly-Gly-OH
Ile-Gly-Gly-OH. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
Ile-Gly-OH. Group: Biochemicals. Alternative Names: L-Isoleucyl-glycine. Grades: Highly Purified. CAS No. 868-28-0. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
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Ile-Gly-OH 99+%
Ile-Gly-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 868-28-0. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
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Ile-His
Isoleucyl-histidine is a dipeptide composed of isoleucine and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: Isoleucyl-Histidine; L-Ile-L-His. Grades: ≥95% by HPLC. CAS No. 97284-12-3. Molecular formula: C12H20N4O3. Mole weight: 268.31.
Ile-Ile-OH. Group: Biochemicals. Alternative Names: L-Isoleucyl-L-isoleucine. Grades: Highly Purified. CAS No. 42537-99-5. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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Ile-Ile-OH 98+% (HPLC)
Ile-Ile-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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Ile-Phe
Ile-Phe and similar dipeptides may serve as models for studying the first steps of the aggregation/fibrillation of amyloid peptides. Synonyms: Isoleucyl-Phenylalanine; L-Ile-L-Phe; L-Phenylalanine,L-isoleucyl-. CAS No. 22951-98-0. Molecular formula: C15H22N2O3. Mole weight: 278.35.
Ile-Tyr-OH. Group: Biochemicals. Alternative Names: L-Isoleucyl-L-tyrosine. Grades: Highly Purified. CAS No. 38579-21-4. Pack Sizes: 250mg. US Biological Life Sciences.
Ile-Tyr-OH 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
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Ilexgenin A
Botanical Source: Group: Biochemicals. Alternative Names: Myriaboric acid. Grades: Plant Grade. CAS No. 108524-94-3. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
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Ilexhainanoside D
Ilexhainanoside D. Group: Biochemicals. CAS No. 1137648-52-2. Pack Sizes: 5mg. US Biological Life Sciences.
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Ilexoside D
Ilexoside D. Group: Biochemicals. CAS No. 109008-27-7. Pack Sizes: 5mg. US Biological Life Sciences.
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Ilexoside K
Ilexoside K. Group: Biochemicals. CAS No. 109008-26-6. Pack Sizes: 5mg. US Biological Life Sciences.
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Ilexsaponin A
Ilexsaponin A. Group: Biochemicals. CAS No. 108524-93-2. Pack Sizes: 5mg. US Biological Life Sciences.
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Ilexsaponin A
Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 108524-93-2. Molecular formula: C36H56O11. Mole weight: 664.83. Purity: 0.98. IUPACName: (3S,4R,4aR,6aR,6bS,8aS,11R,12R,12aS,14aR,14bR)-3,12-dihydroxy-4,6a,6b,11,12,14b-hexamethyl-8a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,2,3,4a,5,6,7,8,9,10,11,12a,14,14a-tetradecahydropicene-4-carboxylic acid. Canonical SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C(=O)O)O)C)C)C2C1(C)O)C)C(=O)OC6C(C(C(C(O6)CO)O)O)O. Product ID: ACM108524932. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ilexsaponin A1.
Ilexsaponin A1
Botanical Source: Group: Biochemicals. Alternative Names: Ilexsaponina A. Grades: Plant Grade. CAS No. 108524-93-2. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
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Iliac Artery Endothelial Cells, Human (Frozen)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
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Iliac Artery Endothelial Cells, Human (T-25 flask)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
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Ilicicolin A
Ilicicolin A is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibited Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells was 0.2 μg/mL. Synonyms: LL-Z 1272-alpha; 3-chloro-4,6-dihydroxy-2-methyl-5-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzaldehyde. Grades: >98%. CAS No. 22581-06-2. Molecular formula: C23H31ClO3. Mole weight: 390.94.
Ilicicolin B
Ilicicolin B is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibited Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells was 0.3 μg/mL. Synonyms: 2,4-Dihydroxy-6-methyl-3-((2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl)benzaldehyde; LL-Z1272beta. Grades: >98%. CAS No. 22581-07-3. Molecular formula: C23H32O3. Mole weight: 356.50.
Ilicicolin C
Ilicicolin C is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibits Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells is 0.2 μg/mL. Synonyms: LL-Z 1272delta; 3-Chloro-4,6-dihydroxy-2-methyl-5-((2E)-3-methyl-5-((1S,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl)-2-pentenyl)benzaldehyde. Grades: >95%. CAS No. 22562-67-0. Molecular formula: C23H31ClO4. Mole weight: 406.94.
Ilicicolin F
?98% (HPLC), from Verticillium hemipterigenum. Group: Fluorescence/luminescence spectroscopy.
Ilimaquinone
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Epiilimaquinone. Product Category: Inhibitors. Appearance: Solid. CAS No. 71678-03-0. Molecular formula: C22H30O4. Mole weight: 358.5. Purity: 95%+. IUPACName: 3-[[(1R,2S,4aS,8aS)-1,2,4a-Trimethyl-5-methylidene-3,4,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl]-2-hydroxy-5-methoxycyclohexa-2,5-diene-1,4-dione. Canonical SMILES: CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C. Density: 1.14±0.1 g/cm³. Product ID: ACM71678030. Alfa Chemistry ISO 9001:2015 Certified.
Ilimaquinone
Ilimaquinone is a marine sponge metabolite with antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. Ilimaquinone significantly enhanced TRAIL-induced apoptosis in HCT 116 cells and sensitized colon cancer cells to TRAIL-induced apoptosis through increased caspase-8, -3 activation, PARP cleavage, and DNA damage. Ilimaquinone also reduced the cell survival proteins Bcl2 and Bcl-xL, while strongly up-regulating death receptor (DR) 4 and DR5 expression. Synonyms: ilimaquinone; 71678-03-0; Illimaquinone; UNII-5U0WAN3N8Q5U0WAN3N8Q. Grades: ≥98%. CAS No. 71678-03-0. Molecular formula: C22H30O4. Mole weight: 358.5.
Ilimaquinone
Cytoplasmic microtubule inhibitor. Cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures. Blocks the association of the ADP-ribosylation factor and beta-COP to the Golgi membrane. Blocks protein transport to the plasma membrane and inhibits gap junctional communication. HIV-1 inhibitor. Blocks the cytotoxicity of ricin and diphtheria toxin. S-Adenosylhomocysteinase hydrolase inhibitor and cellular methylations inhibitor. DNA polymerase beta lyase activity inhibitor. Anti-cancer compound. Source:Isolated from Anthelia sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 71678-03-0. Pack Sizes: 100ug. Molecular Formula: C22H30O4. US Biological Life Sciences.
Worldwide
Ilimaquinone
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus [1]. Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects [2]. Uses: Scientific research. Group: Natural products. CAS No. 71678-03-0. Pack Sizes: 100 μg. Product ID: HY-119500.
Ilimaquinone - CAS 71678-03-0
A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Group: Fluorescence/luminescence spectroscopy.
ILK-IN-1
ILK-IN-1, a ILK inhibitor, has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. IC50: 0.6 μM. Uses: Ilk-in-1 is a ilk inhibitor that has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. Synonyms: ILK-IN-1; CHEMBL1830587; GTPL8116; SCHEMBL8536228; BDBM50353484; CS-4936; ILK inhibitor 22(1,5); T315(1,5); OSU-T315 (1,5-regioisomer); OSUT315; OSU T315; OSU-T315. Grades: 98%. CAS No. 1333146-24-9. Molecular formula: C30H30F3N5O. Mole weight: 533.59.
A cell-permeable, tri-substituted pyrazol compound that acts as a potent and specific integrin-linked kinase (ILK) inhibitor (IC50=600nM). Shown to have high in vitro anti-proliferative potency against prostrate and breast cancer cell lines (IC50=1 to 2.5uM) while sparing normal epithelial cells. Its effect on cancer cells have been attributed to induction of autophagy and apoptosis. Suppresses ILK-mediated phosphorylation of Akt at Ser473 site, thereby down-regulating the downstream targets, such as GSK-3b and myosin light chain. Also causes a transcriptional repression of the transcription factor Y-Box binding protein 1 (YB-1). Exhibits minimum toxicity in mouse model. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C30H30F3N5O, Molecular Weight: 553.6. US Biological Life Sciences.
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Illudin C2
Illudin C2 is produced by the strain of Coprinus atramentarius ASI 20013. It has the effect of resisting bacterium and fungus, and the antibacterial activity is weak. Molecular formula: C15H20O3. Mole weight: 248.32.
Illudin M
Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Synonyms: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grades: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32.
Illudin S
Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Illudin S; DR-15978; DR 15978; DR15978; NSC 626369; NSC-626369; NSC626369; Lunamycin; Lampterol. Product Category: Others. Appearance: Solid powder. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. Purity: 0.98. IUPACName: (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one. Canonical SMILES: CC1=C2[C@H]([C@](CO)(C=C2C([C@](O)(C13CC3)C)=O)C)O. Product ID: ACM1149991. Alfa Chemistry ISO 9001:2015 Certified.
Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Synonyms: GM6001; GM-6001; GM 6001; Ilomastat; galardin; (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanedia. Grades: 98%. CAS No. 142880-36-2. Molecular formula: C20H28N4O4. Mole weight: 388.468.
Ilonidap
Ilonidap is an anti-Inflammatory agent. No detailed information has been published yet. Uses: Anti-inflammatory agent. Synonyms: Ilonidap; CP-72,133; CP-72133; CP72,133; (3Z)-6-chloro-5-fluoro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxoindole-1-carboxamide; Ilonidap(USAN/INN); SCHEMBL42518; 135202-79-8; D04506. Grades: 95%. CAS No. 135202-79-8. Molecular formula: C14H8ClFN2O3S. Mole weight: 338.74.
Iloperidone
Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1- [4- [3- [4- (6-Fluoro-1, 2-benzisoxazol-3-yl) -1-piperidinyl] propoxy] -3-methoxyphenyl] ethanone. Grades: Highly Purified. CAS No. 133454-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
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Iloperidone
Iloperidone (HP 873) is a D 2 /5-HT 2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HP 873. CAS No. 133454-47-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17410.
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Antihistamines standards.
Iloperidone carboxylic acid
Iloperidone carboxylic acid. Group: Biochemicals. Alternative Names: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxybenzoic acid; P 95-12113. Grades: Highly Purified. CAS No. 475110-48-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H25FN2O5. US Biological Life Sciences.
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Iloperidone-d3
Labeled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Grades: Highly Purified. CAS No. 1071167-49-1. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Iloperidone-d3
Iloperidone-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 1071167-49-1. Molecular formula: C24H24D3FN2O4. Mole weight: 429.5. Purity: 0.96. IUPACName: 1-(4-(3-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-(d. Product ID: ACM1071167491. Alfa Chemistry ISO 9001:2015 Certified.
Iloperidone Dimer Impurity
Iloperidone Dimer is an impurity of Iloperidone. Synonyms: 1-{4-[3-(4-{6-[4-(6-Fluoro-3a,7a-dihydro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-3a,7a-dihydro-benzo[d]isoxazol-3-yl}-piperidin-1-yl)-propoxy]-3-methoxy-phenyl}-ethanone. Grades: > 95%. CAS No. 1375651-23-2. Molecular formula: C36H39FN4O5. Mole weight: 626.73.
Iloperidone hydrochloride
The hydrochloride salt form of Iloperidone which is a antagonist of both D2 and 5-HT2 receptor and has been commonly used against schizophrenia. IC50: 10-100 nm and <10nM for D2 and 5-HT2 receptors respectively (Ki). Uses: The hydrochloride salt form of iloperidone which is a antagonist of both d2 and 5-ht2 receptor and has been commonly used against schizophrenia. Synonyms: Iloperidone D3 Hydrochloride; CS-O-02812. Grades: 98%. CAS No. 1299470-39-5. Molecular formula: C24H28ClFN2O4. Mole weight: 465.96.
Iloperidone Impurity 1
an intermediate used to prepare Iloperidone derivatives. Synonyms: 1-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]-ethanone. Grades: > 95%. CAS No. 207298-39-3. Molecular formula: C12H16O4. Mole weight: 224.26.
Iloperidone impurity 10
Iloperidone impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 170170-50-0. Molecular formula: C24H28FNO5. Mole weight: 429.49. Catalog: APB170170500.
an intermediate in the synthesis of Iloperidone Dimer Impurity. It is also an impurity of the drug Iloperidone. Synonyms: 6-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-3-(4-piperidinyl)-1,2-benzisoxazole. Grades: > 95%. CAS No. 531524-17-1. Molecular formula: C24H25FN4O2. Mole weight: 420.49.
Iloperidone impurity 14
Iloperidone impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133454-46-3. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB133454463.
an impurity of Iloperidone; intermediate in the preparation of Risperidone and it's derivatives. Solubility in methanol. Synonyms: (E)-4-(2,4-Difluorobenzoyl)piperidine Oxime; (1E)-(2,4-Difluorophenyl)-4-piperidinyl-methanone Oxime. Grades: > 95%. CAS No. 691007-07-5. Molecular formula: C12H14F2N2O. Mole weight: 240.25.