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| Product | Description | |
|---|---|---|
| Ilicicolin F | ?98% (HPLC), from Verticillium hemipterigenum. Group: Fluorescence/luminescence spectroscopy. |  |
| Ilimaquinone | Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus [1]. Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects [2]. Uses: Scientific research. Group: Natural products. CAS No. 71678-03-0. Pack Sizes: 100 μg. Product ID: HY-119500. |  |
| Ilimaquinone | Cytoplasmic microtubule inhibitor. Cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures. Blocks the association of the ADP-ribosylation factor and beta-COP to the Golgi membrane. Blocks protein transport to the plasma membrane and inhibits gap junctional communication. HIV-1 inhibitor. Blocks the cytotoxicity of ricin and diphtheria toxin. S-Adenosylhomocysteinase hydrolase inhibitor and cellular methylations inhibitor. DNA polymerase beta lyase activity inhibitor. Anti-cancer compound. Source:Isolated from Anthelia sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 71678-03-0. Pack Sizes: 100ug. Molecular Formula: C22H30O4. US Biological Life Sciences. |  Worldwide |
| Ilimaquinone | Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Epiilimaquinone. Product Category: Inhibitors. Appearance: Solid. CAS No. 71678-03-0. Molecular formula: C22H30O4. Mole weight: 358.5. Purity: 95%+. IUPACName: 3-[[(1R,2S,4aS,8aS)-1,2,4a-Trimethyl-5-methylidene-3,4,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl]-2-hydroxy-5-methoxycyclohexa-2,5-diene-1,4-dione. Canonical SMILES: CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C. Density: 1.14±0.1 g/cm³. Product ID: ACM71678030. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ilimaquinone - CAS 71678-03-0 | A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Group: Fluorescence/luminescence spectroscopy. | |
| ILK Inhibitor, Cpd 22 (N-methyl-3- (1- (4- (piperazin-1-yl) phenyl) -5- (4'- (trifluoromethyl) biphenyl-4-yl) -1H-pyrazol-3-yl) propanamide) | A cell-permeable, tri-substituted pyrazol compound that acts as a potent and specific integrin-linked kinase (ILK) inhibitor (IC50=600nM). Shown to have high in vitro anti-proliferative potency against prostrate and breast cancer cell lines (IC50=1 to 2.5uM) while sparing normal epithelial cells. Its effect on cancer cells have been attributed to induction of autophagy and apoptosis. Suppresses ILK-mediated phosphorylation of Akt at Ser473 site, thereby down-regulating the downstream targets, such as GSK-3b and myosin light chain. Also causes a transcriptional repression of the transcription factor Y-Box binding protein 1 (YB-1). Exhibits minimum toxicity in mouse model. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C30H30F3N5O, Molecular Weight: 553.6. US Biological Life Sciences. | Worldwide |
| Illudin C2 | Illudin C2 is produced by the strain of Coprinus atramentarius ASI 20013. It has the effect of resisting bacterium and fungus, and the antibacterial activity is weak. Molecular formula: C15H20O3. Mole weight: 248.32. |  |
| Illudin M | Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Synonyms: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grade: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Illudin S | Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. Synonyms: (-)-Illudin S; Lampterol; Lunamycin; (-)-1alpha,7beta,12-trihydroxy-2,9-illudadien-8-one; 2',3'-Dihydro-2',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. Grade: >98% by HPLC. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Illudin S | Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Illudin S; DR-15978; DR 15978; DR15978; NSC 626369; NSC-626369; NSC626369; Lunamycin; Lampterol. Product Category: Others. Appearance: Solid powder. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. Purity: 0.98. IUPACName: (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one. Canonical SMILES: CC1=C2[C@H]([C@](CO)(C=C2C([C@](O)(C13CC3)C)=O)C)O. Product ID: ACM1149991. Alfa Chemistry ISO 9001:2015 Certified. | |
| Illudin S | Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells[1][2][3][4]. Uses: Scientific research. Group: Natural products. CAS No. 1149-99-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-125098. | |
| Ilmofosine | ?97% (NMR), semisolid (waxy). Group: Fluorescence/luminescence spectroscopy. | |
| Ilomastat | Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GM6001; Galardin. CAS No. 142880-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15768. | |
| Iloperidone | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopypharmaceutical toxicology. | |
| Iloperidone | Iloperidone displays high affinity (Ki < 10 nM) for norepinephrine alpha(1)-adrenoceptors, dopamine D(3) and serotonin 5-HT(2A) receptors. Uses: An atypical, negative symptom antipsychotic agent. Synonyms: HP873; HP 873; HP-873. Grade:>98%. CAS No. 133454-47-4. Molecular formula: C24H27FN2O4. Mole weight: 426.48. | |
| Iloperidone | Iloperidone (HP 873) is a D 2 /5-HT 2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HP 873. CAS No. 133454-47-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17410. | |
| Iloperidone | Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1- [4- [3- [4- (6-Fluoro-1, 2-benzisoxazol-3-yl) -1-piperidinyl] propoxy] -3-methoxyphenyl] ethanone. Grades: Highly Purified. CAS No. 133454-47-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Iloperidone-13C,D3 solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Antihistamines standards. | |
| Iloperidone carboxylic acid | Iloperidone carboxylic acid. Group: Biochemicals. Alternative Names: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxybenzoic acid; P 95-12113. Grades: Highly Purified. CAS No. 475110-48-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H25FN2O5. US Biological Life Sciences. | Worldwide |
| Iloperidone-d3 | Iloperidone-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 1071167-49-1. Molecular formula: C24H24D3FN2O4. Mole weight: 429.5. Purity: 0.96. IUPACName: 1-(4-(3-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-(d. Product ID: ACM1071167491. Alfa Chemistry ISO 9001:2015 Certified. | |
| Iloperidone-d3 | Labeled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Grades: Highly Purified. CAS No. 1071167-49-1. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Iloperidone-[d3] | Iloperidone-[d3] is an isotopically labelled analogue of Iloperidone. Iloperidone is an atypical antipsychotic, a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Uses: Labelled iloperidone. combined dopamine (d2) and serotonin (5ht2) receptor antagonist. antipsychotic. Synonyms: Iloperidone D3. Grade: 95% atom D. CAS No. 1071167-49-1. Molecular formula: C24H24D3FN2O4. Mole weight: 411.5. | |
| Iloperidone impurity 10 | Iloperidone impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 170170-50-0. Molecular formula: C24H28FNO5. Mole weight: 429.49. Catalog: APB170170500. | |
| Iloperidone impurity 11 | Iloperidone impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133454-55-4. Molecular formula: C24H29FN2O4. Mole weight: 428.5. Catalog: APB133454554. | |
| Iloperidone impurity 14 | Iloperidone impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133454-46-3. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB133454463. | |
| Iloperidone impurity 25 | Iloperidone impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1233644-64-8. Molecular formula: C24H28F2N2O4. Mole weight: 446.49. Catalog: APB1233644648. | |
| Iloperidone impurity 29 | Iloperidone impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1226154-13-7. Molecular formula: C12H13F2NO. Mole weight: 225.24. Catalog: APB1226154137. | |
| Iloperidone impurity 35 | Iloperidone impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133455-04-6. Molecular formula: C25H29FN2O4. Mole weight: 440.52. Catalog: APB133455046. | |
| Iloperidone solution | 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| Iloprost | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ciloprost; ZK 36374. CAS No. 78919-13-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0096. | |
| Iloprost | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: Ciloprost, (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane, Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)- (9CI),Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-, Endoprost, ZK 36374, (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid, Ilomedin, Iloprost. | |
| Iloprost | Iloprost. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Iloprost. Product Category: Heterocyclic Organic Compound. CAS No. 73873-87-7. Molecular formula: C22H32O4. Mole weight: 360.49. Product ID: ACM73873877. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ilorasertib | Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF , PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348. CAS No. 1227939-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018. | |
| Ilorasertib hydrochloride | Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF , PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348 hydrochloride. CAS No. 1847485-91-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018A. | |
| ILP | ILP is an analog of insulin, a pancreatic hormone that regulates glucose metabolism, cellular uptake, as well as the storage of glucose, amino acids and fatty acids. Synonyms: Insulin-like peptide; Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Asp-Leu-Ala-Asp-Asn-Ile-Glu-Arg-Leu-Lys-Ala-Asn-Asp-Gly-Leu-Lys-Phe-Ser-Gln-Glu-Tyr-Glu-Ser-Ile-NH2. Molecular formula: C178H303N65O54S. Mole weight: 4250.00. | |
| ILS-920 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ilunocitinib | Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-3411067. CAS No. 1187594-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132819. | |
| Ilutinib impurity 10 | Ilutinib impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. Catalog: APB1022150113. | |
| Iluzanebart | Iluzanebart is a human monoclonal IgG1 antibody and is the agonist antibody for human TREM2 (hTREM2). Iluzanebart improves the survival and function of microglia by activating the TREM2 signaling pathway to compensate for the loss of CSF1R function. Iluzanebart can be used for research of adult-onset leukoencephalopathy associated with CSF1R (colony stimulating factor 1 receptor) (CSF1R-ALSP)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VGL101. CAS No. 2733621-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990043. | |
| Im-1 | Im-1 is an antibacterial peptide isolated from Isometrus maculatus (Lesser brown scorpion). It has activity against gram-positive bacteria, gram-negative bacteria and Parasites. Synonyms: Phe-Ser-Phe-Lys-Arg-Leu-Lys-Gly-Phe-Ala-Lys-Lys-Leu-Trp-Asn-Ser-Lys-Leu-Ala-Arg-Lys-Ile-Arg-Thr-Lys-Gly-Leu-Lys-Tyr-Val-Lys-Asn-Phe-Ala-Lys-Asp-Met-Leu-Ser-Glu-Gly-Glu-Glu-Ala-Pro-Pro-Ala-Ala-Glu-Pro-Pro-Val-Glu-Ala-Pro-Gln. Molecular formula: C292H467N79O77S. Mole weight: 6348.46. | |
| IM-12 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IM-12 | IM-12 is an inhibitor of GSK-3?, with an IC50 of 53 nM, and also enhances Wnt signalling. Uses: Scientific research. Group: Signaling pathways. CAS No. 1129669-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12292. | |
| IM-2 | IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2813269-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160157. | |
| IM-250 | IM-250 is an orally active helicase-primase inhibitor. IM-250 is effective against HSV infection. IM-250 inhibits HSV-1 infection in Vero cells (IC 50 : ~20 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305750-23-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150306. | |
| IM-54 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IMAB027 | IMAB027 (ASP1650) is a specific anti- CLDN6 mAb, while CLDN6 ( Claudin 6 ) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6 + ovarian and testicular cancer cell lines [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASP1650. CAS No. 1650599-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99413. | |
| iMAC2 | iMAC2. Group: Biochemicals. Grades: Purified. CAS No. 335166-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IMAC-Select Affinity Gel | (1:1 suspension in a 30% ethanol solution). Group: Fluorescence/luminescence spectroscopy. | |
| Imanixil | Imanixil. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Imanixil, Imanixilum, Imanixil [INN], UNII-8892KM4U61, CID216289, 4-Amino-2-(4,4-dimethyl-2-oxo-1-imidazolidinyl)-3-(trifluyormethyl)-5-pyrimidincarboxanilid, 75689-93-9. Product Category: Heterocyclic Organic Compound. CAS No. 75689-93-9. Molecular formula: C17H17F3N6O2. Mole weight: 394.355. Purity: 0.96. IUPACName: 4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide. Canonical SMILES: CC1(CN(C(=O)N1)C2=NC=C(C(=N2)N)C(=O)NC3=CC=CC(=C3)C(F)(F)F)C. Density: 1.428g/cm³. Product ID: ACM75689939. Alfa Chemistry ISO 9001:2015 Certified. Categories: Imani Wilcox. | |
| Imaradenant | AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor ( A2AR ) antagonist. AZD4635 binds to human A2AR with a K i of 1.7 nM and shows >30-fold selectivity over other adenosine receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HTL1071; AZD4635. CAS No. 1321514-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101980. | |
| Imatinib | Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL , v-Abl , PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively [1] [2] [3] [4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-15463. | |
| Imatinib | Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Synonyms: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. Grade: >98%. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.60. | |
| Imatinib-[d3] | Imatinib-[d3] is the labelled analogue of Imatinib. Imatinib can be used for the treatment of chronic myelogenous leukemia and acute lymphocytic leukemia. Synonyms: Imatinib D3; Genfatinib-d3; 4-[[4-(methyl-d3)-1-piperazinyl]methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grade: 95% by HPLC; 99% atom D. CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.62. | |
| Imatinib-D3 | Imatinib-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.63. Catalog: APB1134803181. | |
| Imatinib-[d4] | Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Synonyms: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4; Imatinib D4. Grade: ≥98% (HPLC). CAS No. 1134803-16-9. Molecular formula: C29H27D4N7O. Mole weight: 497.64. | |
| Imatinib-D4 | Imatinib-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-16-9. Molecular formula: C29H27D4N7O. Mole weight: 497.64. Catalog: APB1134803169. | |
| Imatinib-d8 | Imatinib-d8 is a deuterated tyrosine kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092942-82-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C29H23D8N7O. US Biological Life Sciences. | Worldwide |
| Imatinib-[d8] | Imatinib-[d8] is the labelled analogue of Imatinib, a treatment of chronic myeloid leukemia. Synonyms: Imatinib D8; 4-[(4-Methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; Genfatinib-d8. Grade: 95% by HPLC; 95% atom D. CAS No. 1092942-82-9. Molecular formula: C29H23D8N7O. Mole weight: 501.65. | |
| Imatinib-d8 Methanesulfonate (STI-571-d8, CGP-57148B-d8) | A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Biochemicals. Alternative Names: Imatinib-d8 Methanesulfonate, STI-571-d8, CGP-57148B-d8, Glivec-d8. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Imatinib free base | Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within tyrosine kinases (TK), thereby inhibiting ATP binding and preventing phosphorylation and the subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene as well as receptor TKs encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Imatinib was approved for medical use in the United States in 2001. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGP 57148; CGP57148; CGP-57148; CGP57148B; CGP-57148B; CGP 57148B; STI571; STI-571; STI 571. Product Category: Inhibitors. Appearance: White to off-white to brownish or yellowish tinged crystalline powder. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.62. Purity: >98%. IUPACName: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. Canonical SMILES: O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4. Product ID: ACM152459955. Alfa Chemistry ISO 9001:2015 Certified. | |
| Imatinib, Free base | An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100ug, 1g. US Biological Life Sciences. | Worldwide |
| Imatinib Imidazole Impurity | Imatinib Imidazole Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256080-10-0. Molecular formula: C32H31N9O2. Mole weight: 573.66. Catalog: APB1256080100. | |
| Imatinib Impurity 12 | Imatinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 112696-91-0. Molecular formula: C16H15N5. Mole weight: 277.33. Catalog: APB112696910. | |
| Imatinib Impurity 16 | Imatinib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152460-09-8. Molecular formula: C16H13N5O2. Mole weight: 307.31. Catalog: APB152460098. | |
| Imatinib Impurity 3 | Imatinib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152459-96-6. Molecular formula: C24H21N5O. Mole weight: 395.47. Catalog: APB152459966. | |
| Imatinib Impurity 36 | Imatinib Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106261-48-7. Molecular formula: C13H18N2O2. Mole weight: 234.3. Catalog: APB106261487. | |
| Imatinib Impurity 5 | Imatinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1032314-73-0. Molecular formula: C17H17N5. Mole weight: 291.36. Catalog: APB1032314730. | |
| Imatinib Impurity 8 | Imatinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1407229-73-5. Molecular formula: C21H25N2O4+. Mole weight: 369.44. Catalog: APB1407229735. | |
| Imatinib impurity D | Imatinib impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine. CAS No. 152460-10-1. Molecular formula: C16H15N5. Mole weight: 277.32. Catalog: APB152460101. | |
| Imatinib impurity J | Imatinib impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one. CAS No. 123367-26-0. Molecular formula: C10H12N2O. Mole weight: 176.22. Catalog: APB123367260. | |
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