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| Product | Description | |
|---|---|---|
| Iloperidone impurity 4 | Iloperidone impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 84163-68-8. Molecular Formula: C12H14N2O. Mole Weight: 202.26. Catalog: APB84163688. |  |
| Iloperidone Impurity 4 | an impurity of Iloperidone,a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Synonyms: 1-Desacetyl 1-Propionyl Iloperidone; 1-(4-(3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-methoxyphenyl)propan-1-one. Grades: > 95%. CAS No. 133455-04-6. Molecular formula: C25H29FN2O4. Mole weight: 440.52. |  |
| Iloperidone impurity 5 | Iloperidone impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 84163-22-4. Molecular Formula: C12H15ClN2O. Mole Weight: 238.72. Catalog: APB84163224. | |
| Iloperidone Impurity 5 | an impurity of Iloperidone,a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Synonyms: 7-Desfluoro 7-Hydroxy Iloperidone; 1-(4-(3-(4-(6-Hydroxybenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-methoxyphenyl)ethanone. Grades: > 95%. Molecular formula: C24H28N2O5. Mole weight: 424.50. | |
| Iloperidone impurity 6 | Iloperidone impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2379325-11-6. Molecular Formula: C24H25F2N3O2. Mole Weight: 425.48. Catalog: APB2379325116. | |
| Iloperidone Impurity 6 | an impurity of Iloperidone, a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Synonyms: Iloperidone 3,4-Dehydropiperidine; 1-(4-(3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)-5,6-dihydropyridin-1(2H)-yl)propoxy)-3-methoxyphenyl)ethanone. Grades: > 95%. Molecular formula: C24H25FN2O4. Mole weight: 424.48. | |
| Iloperidone impurity 7 | Iloperidone impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H26F2N4O2. Mole Weight: 440.49. Catalog: APB11907. | |
| Iloperidone Impurity 7 | an impurity of Iloperidone, a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Synonyms: 7-Desfluoro 5-Fluoro Iloperidone; 1-(4-(3-(4-(4-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-methoxyphenyl)ethanone. Grades: > 95%. Molecular formula: C24H27FN2O4. Mole weight: 426.49. | |
| Iloperidone impurity 8 | Iloperidone impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 98294-54-3. Molecular Formula: C12H14FNO. Mole Weight: 207.25. Catalog: APB98294543. | |
| Iloperidone Impurity 8 | Synonyms: 1-(4-{3-[4-(6-Fluoro-2-oxy-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone. Grades: > 95%. Molecular formula: C24H27FN2O5. Mole weight: 442.49. | |
| Iloperidone impurity 9 | Iloperidone impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64671-29-0. Molecular Formula: C12H15ClFNO. Mole Weight: 243.71. Catalog: APB64671290. | |
| Iloperidone Impurity 9 | an impurity of Iloperidone; intermediate in the preparation of Risperidone and it's derivatives. Solubility in methanol. Synonyms: (E)-4-(2,4-Difluorobenzoyl)piperidine Oxime; (1E)-(2,4-Difluorophenyl)-4-piperidinyl-methanone Oxime. Grades: > 95%. CAS No. 691007-07-5. Molecular formula: C12H14F2N2O. Mole weight: 240.25. | |
| Iloperidone Metabolite P88 Glucuronide | Synonyms: 6-[1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethoxy]-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C30H37FN2O10. Mole weight: 604.64. | |
| Iloperidone Metabolite P88 N-Oxide | Synonyms: 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-1-oxy-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol. Grades: > 95%. Molecular formula: C24H29FN2O5. Mole weight: 444.51. | |
| Iloperidone Metabolite P88 (R-Isomer) | Synonyms: 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol (R-Isomer). Grades: > 95%. Molecular formula: C24H29FN2O4. Mole weight: 428.51. | |
| Iloperidone Metabolite P88 (S-Isomer) | Synonyms: 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol (S-Isomer). Grades: > 95%. Molecular formula: C24H29FN2O4. Mole weight: 428.51. | |
| Iloperidone metabolite P95 | Synonyms: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxybenzoic Acid; P 95-12113. Grades: > 95%. CAS No. 475110-48-6. Molecular formula: C23H25FN2O5. Mole weight: 428.46. | |
| Iloperidone N-Oxide | an impurity in the synthesis of Iloperidone. Synonyms: 1-(3-(4-Acetyl-2-methoxyphenoxy)propyl)-4-(6-fluorobenzo[d]isoxazol-3-yl) piperidine 1-oxide. Grades: > 95%. CAS No. 1375651-09-4. Molecular formula: C24H27FN2O5. Mole weight: 442.49. | |
| Iloprost | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ciloprost; ZK 36374. CAS No. 78919-13-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0096. |  |
| Iloprost | Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. Synonyms: Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid; Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)-; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374. Grades: 98%. CAS No. 78919-13-8. Molecular formula: C22H32O4. Mole weight: 360.49. | |
| Iloprost-d4 | 2H Labeled Compounds. CAS No. 1035094-10-0. Molecular formula: C22H28D4O4. Mole weight: 364.51. Catalog: ACM1035094100. |  |
| Ilorasertib | Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF , PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348. CAS No. 1227939-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018. | |
| Ilorasertib | Ilorasertib, also know as ABT-348, is a novel, potent and orally bioavailable inhibitor of the Aurora kinases as well as the VEGF and PDGF families of receptor tyrosine kinases and is currently in Phase I clinical trials. ABT-348 has nanomolar potency (IC50) for inhibiting binding and cellular auto-phosphorylation of Aurora B (7 and 13 nM), C (1 and 13 nM) and A (120 and 189 nM). These results provide the rationale for clinical assessment of ABT-348 as a therapeutic agent in the treatment of cancer. Uses: Antineoplastic agents. Synonyms: ABT-348; Abbott 968660. Grades: 0.98. CAS No. 1227939-82-3. Molecular formula: C25H21FN6O2S. Mole weight: 488.541. | |
| Ilorasertib hydrochloride | Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF , PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348 hydrochloride. CAS No. 1847485-91-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018A. | |
| Iltbs | Heterocyclic Organic Compound. CAS No. 112168-22-6. Molecular formula: C20H36O4Si. Mole weight: 368.58. Density: 1.03. Catalog: ACM112168226. | |
| Ilunocitinib | Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-3411067. CAS No. 1187594-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132819. | |
| Ilunocitinib | Ilunocitinib is a Janus kinase (JAK) inhibitor (veterinary use). Synonyms: {1-(cyclopropanesulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile; 2-(3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile; 3-Azetidineacetonitrile, 1-(cyclopropylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-. CAS No. 1187594-14-4. Molecular formula: C17H17N7O2S. Mole weight: 383.43. | |
| Ilutinib impurity 10 | Ilutinib impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1022150-11-3. Molecular Formula: C27H30N6O3. Mole Weight: 486.58. Catalog: APB1022150113. | |
| Ilutinib impurity 11 | Ilutinib impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642630-12-3. Molecular Formula: C22H22N6O. Mole Weight: 386.46. Catalog: APB1642630123. | |
| Ilutinib impurity 12 | Ilutinib impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2213398-75-3. Molecular Formula: C18H15N5O. Mole Weight: 317.35. Catalog: APB2213398753. | |
| Ilutinib impurity 13 | Ilutinib impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1899859-31-4. Molecular Formula: C20H25NO5. Mole Weight: 359.42. Catalog: APB1899859314. | |
| Ilutinib impurity 14 | Ilutinib impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2244619-11-0. Molecular Formula: C28H28N6O4. Mole Weight: 512.57. Catalog: APB2244619110. | |
| Ilutinib impurity 15 | Ilutinib impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H48N12O4. Mole Weight: 881.01. Catalog: APB11051. | |
| Ilutinib impurity 16 | Ilutinib impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H48N12O4. Mole Weight: 881.01. Catalog: APB11050. | |
| Ilutinib impurity 17 | Ilutinib impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2417548-83-3. Molecular Formula: C50H48N12O4. Mole Weight: 881.01. Catalog: APB2417548833. | |
| Ilutinib impurity 18 | Ilutinib impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H48N12O4. Mole Weight: 881.01. Catalog: APB11052. | |
| Ilutinib impurity 19 | Ilutinib impurity 19. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H24N6O3S. Mole Weight: 464.54. Catalog: APB11053. | |
| Ilutinib impurity 3 | Ilutinib impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1839099-22-7. Molecular Formula: C25H26N6O2. Mole Weight: 442.52. Catalog: APB1839099227. | |
| Ilutinib impurity 4 | Ilutinib impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H50N12O4. Mole Weight: 883.03. Catalog: APB11044. | |
| Ilutinib impurity 5 | Ilutinib impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H26N6O3. Mole Weight: 458.52. Catalog: APB11045. | |
| Ilutinib impurity 6 | Ilutinib impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H28N6O4. Mole Weight: 512.57. Catalog: APB11046. | |
| Ilutinib impurity 7 | Ilutinib impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C37H47N7O5. Mole Weight: 669.83. Catalog: APB11047. | |
| Ilutinib impurity 8 | Ilutinib impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C33H24N8O3. Mole Weight: 580.61. Catalog: APB11048. | |
| Ilutinib impurity 9 | Ilutinib impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H22N8O2. Mole Weight: 550.58. Catalog: APB11049. | |
| Im-1 | Im-1 is an antibacterial peptide isolated from Isometrus maculatus (Lesser brown scorpion). It has activity against gram-positive bacteria, gram-negative bacteria and Parasites. Synonyms: Phe-Ser-Phe-Lys-Arg-Leu-Lys-Gly-Phe-Ala-Lys-Lys-Leu-Trp-Asn-Ser-Lys-Leu-Ala-Arg-Lys-Ile-Arg-Thr-Lys-Gly-Leu-Lys-Tyr-Val-Lys-Asn-Phe-Ala-Lys-Asp-Met-Leu-Ser-Glu-Gly-Glu-Glu-Ala-Pro-Pro-Ala-Ala-Glu-Pro-Pro-Val-Glu-Ala-Pro-Gln. Molecular formula: C292H467N79O77S. Mole weight: 6348.46. | |
| IM-12 | IM-12 is a potent and selective GSK3β inhibitor with IC50 value of 53 nM. It has been shown to promote neuronal differentiation in neural progenitor cells, and support the conversion and maintenance of human naive stem cells. Synonyms: IM 12; 3-(4-fluorophenethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 1129669-05-1. Molecular formula: C22H20FN3O2. Mole weight: 377.41. | |
| IM-2 | IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2813269-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160157. | |
| IM-250 | IM-250 is an orally active helicase-primase inhibitor. IM-250 is effective against HSV infection. IM-250 inhibits HSV-1 infection in Vero cells (IC 50 : ~20 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305750-23-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150306. | |
| IMAB027 | IMAB027 (ASP1650) is a specific anti- CLDN6 mAb, while CLDN6 ( Claudin 6 ) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6 + ovarian and testicular cancer cell lines [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASP1650. CAS No. 1650599-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99413. | |
| iMAC2 | iMAC2. Group: Biochemicals. Grades: Purified. CAS No. 335166-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Imagabalin | Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. It was developed by Pfizer and is currently in phase III clinical trials for the treatment of generalized anxiety disorder. Uses: Imagabalin has anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. it is used for the treatment of generalized anxiety disorder. Synonyms: (3S,5R)-3-Amino-5-methyloctanoic acid;PD 0332334; PD0332334; PD-0332334; PD 332334; PD332334; PD-332334; PF-00195889; PF 00195889; PF00195889; PF-195889; PF 195889; PF195889; Imagabalin. Grades: 95%. CAS No. 610300-07-7. Molecular formula: C9H19NO2. Mole weight: 173.25. | |
| Imaradenant | AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor ( A2AR ) antagonist. AZD4635 binds to human A2AR with a K i of 1.7 nM and shows >30-fold selectivity over other adenosine receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HTL1071; AZD4635. CAS No. 1321514-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101980. | |
| Imatinib | Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL , v-Abl , PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively [1] [2] [3] [4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-15463. | |
| Imatinib-D3 | Imatinib-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-18-1. Molecular Formula: C29H28D3N7O. Mole Weight: 496.63. Catalog: APB1134803181. | |
| Imatinib-D4 | Imatinib-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-16-9. Molecular Formula: C29H27D4N7O. Mole Weight: 497.64. Catalog: APB1134803169. | |
| Imatinib-d8 | Imatinib-d8 is a deuterated tyrosine kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092942-82-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C29H23D8N7O. US Biological Life Sciences. | Worldwide |
| Imatinib-d8 Methanesulfonate (STI-571-d8, CGP-57148B-d8) | A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Biochemicals. Alternative Names: Imatinib-d8 Methanesulfonate, STI-571-d8, CGP-57148B-d8, Glivec-d8. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Imatinib Dimer Impurity | Imatinib Dimer Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365802-18-1. Molecular Formula: C52H48N12O2. Mole Weight: 873.04. Catalog: APB1365802181. | |
| Imatinib EP Impurity B HCl | Imatinib EP Impurity B HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 581076-67-7. Molecular Formula: C21H29ClN6O. Mole Weight: 416.95. Catalog: APB581076677. | |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1, 4-bis[4-[ (4-methyl-3-[[4- (pyridin-3-yl) pyrimidin-2-yl]amino]phenyl) carbamoyl]benzyl]piperazin-1-ium chloride. Grades: > 95%. CAS No. 1821122-73-9. Molecular formula: C53H51ClN12O2. Mole weight: 923.50. | |
| Imatinib EP Impurity D | Imatinib EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1821122-73-9. Molecular Formula: C53H51N12O2. Mole Weight: 888.07. Catalog: APB1821122739. | |
| Imatinib EP Impurity F | Cas No. 152460-10-1. | |
| Imatinib EP Impurity H | Imatinib EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 350-03-8. Molecular Formula: C7H7NO. Mole Weight: 121.14. Catalog: APB350038. | |
| Imatinib EP Impurity J | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: Imatinib (Piperidine)-N-oxide; 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 71422; CGP71422; CGP-71422. Grades: > 95%. CAS No. 571186-91-9. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib free base | Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within tyrosine kinases (TK), thereby inhibiting ATP binding and preventing phosphorylation and the subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene as well as receptor TKs encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Imatinib was approved for medical use in the United States in 2001. Group: Inhibitors. Alternative Names: CGP 57148; CGP57148; CGP-57148; CGP57148B; CGP-57148B; CGP 57148B; STI571; STI-571; STI 571. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.62. Appearance: White to off-white to brownish or yellowish tinged crystalline powder. Purity: >98%. IUPACName: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. Canonical SMILES: O=C (NC1=CC=C (C)C (NC2=NC=CC (C3=CC=CN=C3)=N2)=C1)C4=CC=C (CN5CCN (C)CC5)C=C4. Catalog: ACM152459955. | |
| Imatinib, Free base | An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100ug, 1g. US Biological Life Sciences. | Worldwide |
| Imatinib Guanidine Impurity | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: N-(3-Guanidino-4-methylphenyl)-4-(methylpiperazine-1-yl-methyl)benzamide; N-[3-[(Aminoiminomethyl)amino]-4-methylphenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; N- [2-Methyl-5- [ [4- [ (4-methylpiperazin-1-yl) methyl] benzoyl] amino] phenyl] guanidine. Grades: > 95%. CAS No. 581076-65-5. Molecular formula: C21H28N6O. Mole weight: 380.50. | |
| Imatinib Imidazole Impurity | Imatinib Imidazole Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256080-10-0. Molecular Formula: C32H31N9O2. Mole Weight: 573.66. Catalog: APB1256080100. | |
| Imatinib Impurity 1 | an impurity of Imatinib. Synonyms: Imatinib Diamine N1-Formyl N3-Methyl Impurity; 6-Methyl-N1-formyl-N3-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine. Grades: > 95%. Molecular formula: C18H17N5O. Mole weight: 319.37. | |
| Imatinib Impurity 11 | Imatinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 796738-71-1. Molecular Formula: C16H13N5O2. Mole Weight: 307.31. Catalog: APB796738711. | |
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