A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Synonyms: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grades: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32.
Illudin S
Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Illudin S; DR-15978; DR 15978; DR15978; NSC 626369; NSC-626369; NSC626369; Lunamycin; Lampterol. Product Category: Others. Appearance: Solid powder. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. Purity: 0.98. IUPACName: (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one. Canonical SMILES: CC1=C2[C@H]([C@](CO)(C=C2C([C@](O)(C13CC3)C)=O)C)O. Product ID: ACM1149991. Alfa Chemistry ISO 9001:2015 Certified.
Illudin S
Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells[1][2][3][4]. Uses: Scientific research. Group: Natural products. CAS No. 1149-99-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-125098.
Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Synonyms: GM6001; GM-6001; GM 6001; Ilomastat; galardin; (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanedia. Grades: 98%. CAS No. 142880-36-2. Molecular formula: C20H28N4O4. Mole weight: 388.468.
Ilomastat
Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GM6001; Galardin. CAS No. 142880-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15768.
Ilonidap
Ilonidap is an anti-Inflammatory agent. No detailed information has been published yet. Uses: Anti-inflammatory agent. Synonyms: Ilonidap; CP-72,133; CP-72133; CP72,133; (3Z)-6-chloro-5-fluoro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxoindole-1-carboxamide; Ilonidap(USAN/INN); SCHEMBL42518; 135202-79-8; D04506. Grades: 95%. CAS No. 135202-79-8. Molecular formula: C14H8ClFN2O3S. Mole weight: 338.74.
Iloperidone
Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1- [4- [3- [4- (6-Fluoro-1, 2-benzisoxazol-3-yl) -1-piperidinyl] propoxy] -3-methoxyphenyl] ethanone. Grades: Highly Purified. CAS No. 133454-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
Iloperidone (HP 873) is a D 2 /5-HT 2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HP 873. CAS No. 133454-47-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17410.
Iloperidone-13C,D3 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Antihistamines standards.
Iloperidone carboxylic acid
Iloperidone carboxylic acid. Group: Biochemicals. Alternative Names: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxybenzoic acid; P 95-12113. Grades: Highly Purified. CAS No. 475110-48-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H25FN2O5. US Biological Life Sciences.
Worldwide
Iloperidone-d3
Labeled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Grades: Highly Purified. CAS No. 1071167-49-1. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Iloperidone-d3
Iloperidone-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(methoxy-d3)phenyl]ethanone. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 1071167-49-1. Molecular formula: C24H24D3FN2O4. Mole weight: 429.5. Purity: 0.96. IUPACName: 1-(4-(3-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)-3-(d. Product ID: ACM1071167491. Alfa Chemistry ISO 9001:2015 Certified.
Iloperidone Dimer Impurity
Iloperidone Dimer is an impurity of Iloperidone. Synonyms: 1-{4-[3-(4-{6-[4-(6-Fluoro-3a,7a-dihydro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-3a,7a-dihydro-benzo[d]isoxazol-3-yl}-piperidin-1-yl)-propoxy]-3-methoxy-phenyl}-ethanone. Grades: > 95%. CAS No. 1375651-23-2. Molecular formula: C36H39FN4O5. Mole weight: 626.73.
Iloperidone hydrochloride
The hydrochloride salt form of Iloperidone which is a antagonist of both D2 and 5-HT2 receptor and has been commonly used against schizophrenia. IC50: 10-100 nm and <10nM for D2 and 5-HT2 receptors respectively (Ki). Uses: The hydrochloride salt form of iloperidone which is a antagonist of both d2 and 5-ht2 receptor and has been commonly used against schizophrenia. Synonyms: Iloperidone D3 Hydrochloride; CS-O-02812. Grades: 98%. CAS No. 1299470-39-5. Molecular formula: C24H28ClFN2O4. Mole weight: 465.96.
Iloperidone Impurity 1
an intermediate used to prepare Iloperidone derivatives. Synonyms: 1-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]-ethanone. Grades: > 95%. CAS No. 207298-39-3. Molecular formula: C12H16O4. Mole weight: 224.26.
Iloperidone impurity 10
Iloperidone impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 170170-50-0. Molecular formula: C24H28FNO5. Mole weight: 429.49. Catalog: APB170170500.
an intermediate in the synthesis of Iloperidone Dimer Impurity. It is also an impurity of the drug Iloperidone. Synonyms: 6-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-3-(4-piperidinyl)-1,2-benzisoxazole. Grades: > 95%. CAS No. 531524-17-1. Molecular formula: C24H25FN4O2. Mole weight: 420.49.
Iloperidone impurity 14
Iloperidone impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133454-46-3. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB133454463.
an impurity of Iloperidone; intermediate in the preparation of Risperidone and it's derivatives. Solubility in methanol. Synonyms: (E)-4-(2,4-Difluorobenzoyl)piperidine Oxime; (1E)-(2,4-Difluorophenyl)-4-piperidinyl-methanone Oxime. Grades: > 95%. CAS No. 691007-07-5. Molecular formula: C12H14F2N2O. Mole weight: 240.25.
Synonyms: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxybenzoic Acid; P 95-12113. Grades: > 95%. CAS No. 475110-48-6. Molecular formula: C23H25FN2O5. Mole weight: 428.46.
Iloperidone N-Oxide
an impurity in the synthesis of Iloperidone. Synonyms: 1-(3-(4-Acetyl-2-methoxyphenoxy)propyl)-4-(6-fluorobenzo[d]isoxazol-3-yl) piperidine 1-oxide. Grades: > 95%. CAS No. 1375651-09-4. Molecular formula: C24H27FN2O5. Mole weight: 442.49.
Iloperidone solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
Iloprost
Iloprost. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Iloprost. Product Category: Heterocyclic Organic Compound. CAS No. 73873-87-7. Molecular formula: C22H32O4. Mole weight: 360.49. Product ID: ACM73873877. Alfa Chemistry ISO 9001:2015 Certified.
Iloprost
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ciloprost; ZK 36374. CAS No. 78919-13-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0096.
Iloprost
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. Synonyms: Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid; Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)-; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374. Grades: 98%. CAS No. 78919-13-8. Molecular formula: C22H32O4. Mole weight: 360.49.
Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF , PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348. CAS No. 1227939-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018.
Ilorasertib
Ilorasertib, also know as ABT-348, is a novel, potent and orally bioavailable inhibitor of the Aurora kinases as well as the VEGF and PDGF families of receptor tyrosine kinases and is currently in Phase I clinical trials. ABT-348 has nanomolar potency (IC50) for inhibiting binding and cellular auto-phosphorylation of Aurora B (7 and 13 nM), C (1 and 13 nM) and A (120 and 189 nM). These results provide the rationale for clinical assessment of ABT-348 as a therapeutic agent in the treatment of cancer. Uses: Antineoplastic agents. Synonyms: ABT-348; Abbott 968660. Grades: 0.98. CAS No. 1227939-82-3. Molecular formula: C25H21FN6O2S. Mole weight: 488.541.
Ilorasertib hydrochloride
Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF , PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348 hydrochloride. CAS No. 1847485-91-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018A.
Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-3411067. CAS No. 1187594-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132819.
Ilunocitinib
Ilunocitinib is a Janus kinase (JAK) inhibitor (veterinary use). Synonyms: {1-(cyclopropanesulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile; 2-(3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile; 3-Azetidineacetonitrile, 1-(cyclopropylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-. CAS No. 1187594-14-4. Molecular formula: C17H17N7O2S. Mole weight: 383.43.
Ilutinib impurity 10
Ilutinib impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. Catalog: APB1022150113.
Iluzanebart
Iluzanebart is a human monoclonal IgG1 antibody and is the agonist antibody for human TREM2 (hTREM2). Iluzanebart improves the survival and function of microglia by activating the TREM2 signaling pathway to compensate for the loss of CSF1R function. Iluzanebart can be used for research of adult-onset leukoencephalopathy associated with CSF1R (colony stimulating factor 1 receptor) (CSF1R-ALSP)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VGL101. CAS No. 2733621-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990043.
Im-1
Im-1 is an antibacterial peptide isolated from Isometrus maculatus (Lesser brown scorpion). It has activity against gram-positive bacteria, gram-negative bacteria and Parasites. Synonyms: Phe-Ser-Phe-Lys-Arg-Leu-Lys-Gly-Phe-Ala-Lys-Lys-Leu-Trp-Asn-Ser-Lys-Leu-Ala-Arg-Lys-Ile-Arg-Thr-Lys-Gly-Leu-Lys-Tyr-Val-Lys-Asn-Phe-Ala-Lys-Asp-Met-Leu-Ser-Glu-Gly-Glu-Glu-Ala-Pro-Pro-Ala-Ala-Glu-Pro-Pro-Val-Glu-Ala-Pro-Gln. Molecular formula: C292H467N79O77S. Mole weight: 6348.46.
IM-12
IM-12 is an inhibitor of GSK-3?, with an IC50 of 53 nM, and also enhances Wnt signalling. Uses: Scientific research. Group: Signaling pathways. CAS No. 1129669-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12292.
IM-12 is a potent and selective GSK3β inhibitor with IC50 value of 53 nM. It has been shown to promote neuronal differentiation in neural progenitor cells, and support the conversion and maintenance of human naive stem cells. Synonyms: IM 12; 3-(4-fluorophenethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 1129669-05-1. Molecular formula: C22H20FN3O2. Mole weight: 377.41.
IM-2
IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2813269-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160157.
IM-250
IM-250 is an orally active helicase-primase inhibitor. IM-250 is effective against HSV infection. IM-250 inhibits HSV-1 infection in Vero cells (IC 50 : ~20 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305750-23-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150306.
IMAB027 (ASP1650) is a specific anti- CLDN6 mAb, while CLDN6 ( Claudin 6 ) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6 + ovarian and testicular cancer cell lines [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASP1650. CAS No. 1650599-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99413.
iMAC2
iMAC2. Group: Biochemicals. Grades: Purified. CAS No. 335166-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IMAC-Select Affinity Gel
(1:1 suspension in a 30% ethanol solution). Group: Fluorescence/luminescence spectroscopy.
Imagabalin
Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. It was developed by Pfizer and is currently in phase III clinical trials for the treatment of generalized anxiety disorder. Uses: Imagabalin has anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. it is used for the treatment of generalized anxiety disorder. Synonyms: (3S,5R)-3-Amino-5-methyloctanoic acid;PD 0332334; PD0332334; PD-0332334; PD 332334; PD332334; PD-332334; PF-00195889; PF 00195889; PF00195889; PF-195889; PF 195889; PF195889; Imagabalin. Grades: 95%. CAS No. 610300-07-7. Molecular formula: C9H19NO2. Mole weight: 173.25.
Imanixil
Imanixil. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Imanixil, Imanixilum, Imanixil [INN], UNII-8892KM4U61, CID216289, 4-Amino-2-(4,4-dimethyl-2-oxo-1-imidazolidinyl)-3-(trifluyormethyl)-5-pyrimidincarboxanilid, 75689-93-9. Product Category: Heterocyclic Organic Compound. CAS No. 75689-93-9. Molecular formula: C17H17F3N6O2. Mole weight: 394.355. Purity: 0.96. IUPACName: 4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide. Canonical SMILES: CC1(CN(C(=O)N1)C2=NC=C(C(=N2)N)C(=O)NC3=CC=CC(=C3)C(F)(F)F)C. Density: 1.428g/cm³. Product ID: ACM75689939. Alfa Chemistry ISO 9001:2015 Certified. Categories: Imani Wilcox.
Imaradenant
AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor ( A2AR ) antagonist. AZD4635 binds to human A2AR with a K i of 1.7 nM and shows >30-fold selectivity over other adenosine receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HTL1071; AZD4635. CAS No. 1321514-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101980.
Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL , v-Abl , PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively [1] [2] [3] [4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-15463.
Imatinib-D3
Imatinib-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.63. Catalog: APB1134803181.