A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ifinatamab deruxtecan (DS-7300a) is an ADC that binds an anti-B7-H3 antibody to the DNA topoisomerase I inhibitory anti-tumor drug DXd. Ifinatamab deruxtecan has antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: DS-7300a; MABX-9001a. CAS No. 2484870-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3371.
Iflab-bb f2108-0112
Iflab-bb f2108-0112. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2108-0112;2-CHLORO-1-PYRIDIN-4-YL-ETHANONE HCL. Product Category: Heterocyclic Organic Compound. CAS No. 25260-36-0. Molecular formula: C7H7Cl2NO. Product ID: ACM25260360. Alfa Chemistry ISO 9001:2015 Certified.
IFLAB-BB F2108-0142
IFLAB-BB F2108-0142. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2108-0142;(2-FLUORO-PHENYL)-PROPYNOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 704-97-2. Molecular formula: C9H5FO2. Product ID: ACM704972. Alfa Chemistry ISO 9001:2015 Certified.
Iflab-bb f2124-0045
Iflab-bb f2124-0045. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2124-0045;5-BROMO-2-METHOXY-PYRIMIDINE-4-CARBOXYLIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 38275-37-5. Molecular formula: C6H5BrN2O3. Mole weight: 233.02. Product ID: ACM38275375. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-bromo-2-methoxypyrimidine-4-carboxylic acid.
Iflab-bb f2124-0085
Iflab-bb f2124-0085. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2124-0085;6-CHLORO-N4-CYCLOHEXYL-PYRIMIDINE-4,5-DIAMINE;(5-amino-6-chloro-pyrimidin-4-yl)-cyclohexyl-amine;6-chloro-4-N-cyclohexylpyrimidine-4,5-diamine. Product Category: Heterocyclic Organic Compound. CAS No. 5449-10-5. Molecular formula: C10H15ClN4. Mole weight: 226.71. Product ID: ACM5449105. Alfa Chemistry ISO 9001:2015 Certified.
IFN alpha-IFNAR-IN-1
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). It exerts immunosuppressive activity by the direct interaction with IFN-&alpha. Uses: Ifn alpha-ifnar-in-1 inhibits mva-induced ifn-α responses by bm-pdcs. it exerts immunosuppressive activity by the direct interaction with ifn-&alpha. Synonyms: IFN-alpha; IFN alpha; IFNAR-IN-1; IFNAR IN 1; IFNARIN1; IFNAR inhibitor 1; IFNAR-inhibitor-1; IFN-alpha and IFNAR interaction inhibitor. Grades: >98%. CAS No. 844882-93-5. Molecular formula: C18H17NS. Mole weight: 279.40.
IFN alpha-IFNAR-IN-1 hydrochloride
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor. It inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3-L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM). Synonyms: IFN-alpha/IFNAR-IN-1 hydrochloride. CAS No. 2070014-98-9. Molecular formula: C18H18ClNS. Mole weight: 315.86.
IFN-γ Antagonist
IFN-γ Antagonist, derived from the ligand binding site of human γ-interferon (IFN-γ) receptor, is an antagonist of human IFN-γ, and inhibits human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an IC50 of about 35 μM. Synonyms: (Tyr121,Cys(Acm)122)-IFN-γ Receptor (120-141) (human); L-Isoleucine, L-alanyl-L-tyrosyl-S-[(acetylamino)methyl]-L-cysteinyl-L-arginyl-L-α-aspartylglycyl-L-lysyl-L-isoleucylglycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-glutaminyl-; L-alanyl-L-tyrosyl-S-acetamidomethyl-L-cysteinyl-L-arginyl-L-alpha-aspartyl-glycyl-L-lysyl-L-isoleucyl-glycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-isoleucine; H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH. Grades: ≥95%. CAS No. 158040-83-6. Molecular formula: C115H194N34O34S. Mole weight: 2629.04.
IFN-γ Antagonist 1
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ ( IFN γ ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC 50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation [1]. Uses: Scientific research. Group: Peptides. CAS No. 158040-83-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4717.
Ifosfamide
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H15Cl2N2O2P. CAS No. 3778-73-2. Prepack ID 43331190-1g. Molecular Weight 261.09. See USA prepack pricing.
Ifosfamide
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Synonyms: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine; (±)-Ifosfamide; 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Holoxan 1000; Ifex; Ifomide; Ifosfamid; Ifosfomide; Ifosphamide; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Mitoxana; MJF 9325; Naxamide; NSC 109724; Z 4942. Grades: >98%. CAS No. 3778-73-2. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09.
Ifosfamide
Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors. Uses: Scientific research. Group: Signaling pathways. CAS No. 3778-73-2. Pack Sizes: 200 mg; 500 mg. Product ID: HY-17419.
Ifosfamide (Asta Z-4942, NSC-1097)
A cytostatic agent, related structurally to cyclophosphamide. Group: Biochemicals. Alternative Names: N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide;A 4942; Asta Z 4942; Cyfos; Holoxan; Ifex; Ifomide; Iphosphamide; MJF 9325; Mitoxana; NSC 109724; Naxamide. Grades: Highly Purified. CAS No. 3778-73-2. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C7H15Cl2N2O2P, Molecular Weight: 261.09. US Biological Life Sciences.
Worldwide
Ifosfamide-d4
A cytostatic agent, related structurally to cyclophosphamide. Group: Biochemicals. Alternative Names: N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide-d4. Grades: Highly Purified. CAS No. 1189701-13-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ifosfamide EP impurity A
Ifosfamide EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 22608-58-8. Molecular Formula: C5H13ClNO4P. Mole Weight: 217.59. Catalog: APB22608588.
Ifosfamide EP impurity B
Ifosfamide EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 241482-18-8. Molecular Formula: C10H24Cl2N2O7P2. Mole Weight: 417.16. Catalog: APB241482188.
Ifosfamide EP impurity C HCl
Ifosfamide EP impurity C HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 870-24-6. Molecular Formula: C2H7Cl2N. Mole Weight: 115.99. Catalog: APB870246.
Ifosfamide EP impurity E
Ifosfamide EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 42453-19-0. Molecular Formula: C5H11Cl2N. Mole Weight: 156.05. Catalog: APB42453190.
Ifosfamide EP impurity F
Ifosfamide EP impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 81485-04-3. Molecular Formula: C5H10Cl2NO2P. Mole Weight: 218.01. Catalog: APB81485043.
IG-105 is a potent microtubule inhibitor with potential anticancer activity. IG-105 inhibits microtubule assembly by binding at colchicine pocket. IG-105 shows a potent anticancer activity in vitro and in vivo and has good safety in mice. IG-105 showed a potent activity against human leukemia and solid tumors in breast, liver, prostate, lung, skin, colon, and pancreas with IC(50) values between 0.012 and 0.298 mumol/L. It was also active in drug-resistant tumor cells and not a P-glycoprotein substrate. It inhibited microtubule assembly followed by M-phase arrest, Bcl-2 inactivation, and then apoptosis through caspase pathways. Synonyms: IG105; IG 105. Grades: 98%. CAS No. 905978-63-4. Molecular formula: C20H19N3O4S. Mole weight: 397.45.
IgA-specific metalloendopeptidase
A 190 kDa enzyme found in several pathogenic species of Streptococcus such as sanguis and pneumoniae. Type example of peptidase family M26. There is also an IgA-specific prolyl endopeptidase of the serine-type (see EC 3.4.21.72, IgA-specific serine endopeptidase). Group: Enzymes. Synonyms: immunoglobulin A1 proteinase; IgA protease; IgA1-specific proteinase; IgA1 protease; IgA1 proteinase. Enzyme Commission Number: EC 3.4.24.13. CAS No. 72231-73-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4294; IgA-specific metalloendopeptidase; EC 3.4.24.13; 72231-73-3; immunoglobulin A1 proteinase; IgA protease; IgA1-specific proteinase; IgA1 protease; IgA1 proteinase. Cat No: EXWM-4294.
IgA-specific serine endopeptidase
Species variants differing slightly in specificity are secreted by Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus influenzae. Type example of peptidase family S6. Some other bacterial endopeptidases with similar specificity are of metallo- type (see EC 3.4.24.13, IgA-specific metalloendopeptidase). Group: Enzymes. Synonyms: IgA protease; IgA proteinase; IgA-specific proteinase; immunoglobulin A protease; immunoglobulin A proteinase. Enzyme Commission Number: EC 3.4.21.72. CAS No. 55127-02-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4164; IgA-specific serine endopeptidase; EC 3.4.21.72; 55127-02-1; IgA protease; IgA proteinase; IgA-specific proteinase; immunoglobulin A protease; immunoglobulin A proteinase. Cat No: EXWM-4164.
IgdE protease
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1892548-76-3. Pack Sizes: 1 KU. Product ID: HY-E70364.
Igepal CO-520
Igepal CO-520. Group: Biochemicals. Alternative Names: Poly(oxy-1,2-ethanediyl),a-(nonylphenyl)-w-hydroxy-, Branched Polymer; α-(Nonylphenyl)-ω-hydroxy-poly(oxy-1,2-ethanediyl) Branched Polymer. Grades: Highly Purified. CAS No. 68412-54-4. Pack Sizes: 1g, 250g, 500g. US Biological Life Sciences.
Worldwide
IGF-1 DES1,3
IGF-1 DES1,3 is a fragment of amino acids of the Insulin Growth Factor-1 DES. Synonyms: Insulin Growth Factor-1 DES. Grades: 99%. CAS No. 67763-96-6. Molecular formula: C18H32N5O7S1. Mole weight: 462.55.
IGF-1 LR3
IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Synonyms: Long R3-IGF-1; IGF-1 Long R3; Long arginine 3-IGF-1. Grades: 95%. CAS No. 946870-92-4. Molecular formula: C400H625N111O115S9. Mole weight: 9117.6.
IGF-I 24-41
IGF-I 24-41 is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41); H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grades: ≥95%. CAS No. 135861-49-3. Molecular formula: C88H133N27O28. Mole weight: 2017.16.
IGF-I 30-41
IGF-I 30-41 is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41); H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grades: ≥95%. CAS No. 82177-09-1. Molecular formula: C51H83N19O19. Mole weight: 1266.32.
IGF-I 30-41 acetate
IGF-I 30-41 acetate is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) acetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.CH3CO2H; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine acetic acid. Grades: ≥95%. Molecular formula: C53H87N19O21. Mole weight: 1326.39.
iGOT1-01
iGOT1-01 is an inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1, GOT1). Uses: Designed for use in research and industrial production. Additional or Alternative Names: iGOT101; iGOT1 01; iGOT1-01; iGOT 101; iGOT-101. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 882256-55-5. Molecular formula: C19H20N4O. Mole weight: 320.4. Purity: >98%. IUPACName: 4-(1H-Indol-4-yl)-N-phenylpiperazine-1-carboxamide. Canonical SMILES: O=C(N1CCN(C2=CC=CC3=C2C=CN3)CC1)NC4=CC=CC=C4. Product ID: ACM882256555. Alfa Chemistry ISO 9001:2015 Certified.
Iguratimod
Iguratimod. Group: Biochemicals. Alternative Names: N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]-methanesulfonamide; 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one; Careram; Kolbet; N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-chromen-7-yl]methanesulfonamide; T 614; T 614 (antiinflammatory). Grades: Highly Purified. CAS No. 123663-49-0. Pack Sizes: 10mg. Molecular Formula: C17H14N2O6S, Molecular Weight: 374.37. US Biological Life Sciences.
Worldwide
Iguratimod
Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Synonyms: T 614; T-614; T614; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; Careram; Kolbet; UNII-4IHY34Y2NV. Grades: 0.98. CAS No. 123663-49-0. Molecular formula: C17H14N2O6S. Mole weight: 374.367.
Iguratimod
Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2 , with an IC 50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor ( MIF ) with an IC 50 of 6.81 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T614. CAS No. 123663-49-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17009.
Iguratimod Impurity 1
Iguratimod Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2375563-22-5. Molecular Formula: C15H17NO6S2. Mole Weight: 371.42. Catalog: APB2375563225.
Iguratimod Impurity 10
Iguratimod Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(2-methoxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)formamide. CAS No. 149456-98-4. Molecular Formula: C17H18N2O6S. Mole Weight: 378.40. Catalog: APB149456984.
Iguratimod Impurity 11
Iguratimod Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(2-hydroxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)formamide. CAS No. 149457-03-4. Molecular Formula: C16H16N2O6S. Mole Weight: 364.37. Catalog: APB149457034.
Iguratimod Impurity 20
Iguratimod Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123663-50-3. Molecular Formula: C18H16N2O6S. Mole Weight: 388.39. Catalog: APB123663503.
Iguratimod Impurity 28
Iguratimod Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-chloro-5-methoxyphenyl)methanesulfonamide. CAS No. 1340086-28-3. Molecular Formula: C8H10ClNO3S. Mole Weight: 235.69. Catalog: APB1340086283.
Iguratimod Impurity 3
Iguratimod Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-methoxy-2-phenoxyaniline. CAS No. 76838-72-7. Molecular Formula: C13H13NO2. Mole Weight: 215.25. Catalog: APB76838727.
Iguratimod Impurity 30
Iguratimod Impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123663-48-9. Molecular Formula: C16H14N2O5S. Mole Weight: 346.36. Catalog: APB123663489.
Iguratimod Impurity 32 (Hydrochloride)
Iguratimod Impurity 32 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride. CAS No. 149436-41-9. Molecular Formula: C16H18N2O5S·HCl. Mole Weight: 386.85. Catalog: APB149436419.
Iguratimod Impurity 33
Iguratimod Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150831-14-4. Molecular Formula: C15H16N2O5S. Mole Weight: 336.36. Catalog: APB150831144.
Iguratimod Impurity 35
Iguratimod Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10298-80-3. Molecular Formula: C7H6ClNO3. Mole Weight: 187.58. Catalog: APB10298803.
Iguratimod Impurity 4
Iguratimod Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(5-methoxy-2-phenoxyphenyl)methanesulfonamide. CAS No. 123664-84-6. Molecular Formula: C14H15NO4S. Mole Weight: 293.34. Catalog: APB123664846.
Iguratimod Impurity 46
Iguratimod Impurity 46. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16156-59-5. Molecular Formula: C7H8O3S. Mole Weight: 172.2. Catalog: APB16156595.
Iguratimod Impurity 48
Iguratimod Impurity 48. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144150-51-6. Molecular Formula: C9H10ClNO5S. Mole Weight: 279.69. Catalog: APB144150516.
Iguratimod Impurity 5
Iguratimod Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-5-methoxyaniline. CAS No. 2401-24-3. Molecular Formula: C7H8ClNO. Mole Weight: 157.60. Catalog: APB2401243.
Iguratimod Impurity 8
Iguratimod Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(2-methoxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)acetamide. CAS No. 149456-97-3. Molecular Formula: C18H20N2O6S. Mole Weight: 392.43. Catalog: APB149456973.
Iguratimod Impurity 9
Iguratimod Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(2-hydroxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)acetamide. CAS No. 149457-04-5. Molecular Formula: C17H18N2O6S. Mole Weight: 378.40. Catalog: APB149457045.
Iguratimod Impurity 9
Iguratimod Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 544482-14-6. Molecular Formula: C18H18N2O7S. Mole Weight: 406.41. Catalog: APB544482146.
Iguratimod Impurity E
Iguratimod Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(7-(methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)acetamide. CAS No. 123662-92-0. Molecular Formula: C18H16N2O6S. Mole Weight: 388.39. Catalog: APB123662920.
IHMT-PI3Kδ-372 S-isomer
An S isomer of IHMT-PI3Kδ-372, a potent and selective PI3Kδ inhibitor used for the treatment of chronic obstructive pulmonary disease. Synonyms: 2-[(1S)-1-[4-Amino-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]propyl]-3-cyclopropyl-5-fluoro-4(3H)-quinazolinone. CAS No. 2429889-61-0. Molecular formula: C26H23F2N7O2. Mole weight: 503.5.
IHR 1
IHR 1 is a potent and cell-membrane-impermeable Smo antagonist with IC50 value of 7.6 nM. It blocks hedgehog induced movement of Smo and blocks Smo accumulation into the primary cilium. It selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Synonyms: IHR-1; IHR 1; IHR1; N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]. Grades: ≥99% by HPLC. CAS No. 548779-60-8. Molecular formula: C20H12Cl4N2O2. Mole weight: 454.13.
IHR-1
IHR-1 is a cell membrane impermeable Smo antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 548779-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110240.
IHR-Cy3
IHR-Cy3 is a potent fluorescent Smo antagonist with IC50 value of 100 nM. Synonyms: (2-[3-[1- (6-[[7-[[4-Chloro-3-[[4- (2, 5-dichlorobenzamido) phenyl]carbamoyl]phenyl]amino]-7-oxoheptylamino]-6-oxohexyl]-1, 3-dihydro-3, 3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1-ethyl-3, 3-dimethyl-5-sulfo-3H-indolium, inner salt. Grades: ≥95% by HPLC. Molecular formula: C58H63Cl3N6O10S2. Mole weight: 1174.64.
II-B08
This active molecular is a cell-permeable SHP2 inhibitor which blocks growth factor stimulated hematopoietic progenitor proliferation and ERK1/2 activation. IC50 is 5.5 μM. II-B08 may be therapeutically useful for anticancer and antileukemia treatment in the future. Uses: Anticancer and antileukemia treatment. Synonyms: II-B08; II-B 08; II-B-08. CD45 Inhibitor V, FAP1 Inhibitor, LMWPTP Inhibitor, Lyp Inhibitor III, PTP1B Inhibitor IX, SHP1 Inhibitor IX. 3-(1-(3-(Biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3-triazol-4-yl)-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid,CD45 Inhibitor V, FAP1 Inhibitor, LMWPTP Inhibitor, Lyp Inhibitor III, PTP1B Inhibitor IX, SHP1 Inhibitor IX. Grades: 98%. CAS No. 1143579-78-5. Molecular formula: C33H27N5O4. Mole weight: 557.61.
IITZ-01
IITZ-01 is a potent autophagy inhibitor that is accumulated in lysosomes. IITZ-01 exhibited anticancer effects in MDA-MB-231 breast cancer xenograft model. Synonyms: EX-A2763; HY-112897; AK00792538; 4-N-[4-(1H-benzimidazol-2-yl)phenyl]-2-N-(4-fluorophenyl)-6-morpholin-4-yl-1,3,5-triazine-2,4-diamine. CAS No. 1807988-47-1. Molecular formula: C26H23FN8O. Mole weight: 482.51.
IK-930
IK930, a novel TEAD inhibitor, sensitizes KRAS and EGFR mutant tumors to oncogene targeted therapy. CAS No. 2563892-44-2. Molecular formula: C19H19F3N4O2S. Mole weight: 424.44.
IK-930
IK-930 (compound I-32) is a potent and orally active TEAD inhibitor with an EC 50 value of <0.1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2563892-44-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153585.
IκB kinase
The enzyme phosphorylates IκB proteins at specific serine residues, which marks them for destruction via the ubiquitination pathway. Subsequent degradation of the IkB complex (IKK) activates NF-κB, a translation factor that plays an important role in inflammation, immunity, cell proliferation and apoptosis. If the serine residues are replaced by threonine residues, the activity of the enzyme is decreased considerably. Group: Enzymes. Synonyms: CHUK; IKBKA; IKBKB; IKK; IKK-1; IKK-2; inhibitor of NFκB kinase; inhibitor of NF-κB kinase; STK12; TANK-binding kinase 1; TBK1. Enzyme Commission Number: EC 2.7.11.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3129; IκB kinase; EC 2.7.11.10; CHUK; IKBKA; IKBKB; IKK; IKK-1; IKK-2; inhibitor of NFκB kinase; inhibitor of NF-κB kinase; STK12; TANK-binding kinase 1; TBK1. Cat No: EXWM-3129.
Ikarisoside F
Ikarisoside F, a flavonol glycoside from Vancouveria hexandra, could bind to AdoHcy hydrolase. Synonyms: Ikarisoside F. Grades: >98%. CAS No. 113558-14-8. Molecular formula: C31H36O14. Mole weight: 632.61.
Ikarugamycin
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) [1]. Uses: Scientific research. Group: Natural products. CAS No. 36531-78-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-119764.