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| Product | Description | |
|---|---|---|
| Idarubicinol-d4 | Idarubicinol-d4 is a labelled Idarubicinol. Synonyms: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grade: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55. |  |
| Idarubicinol (Mixture of Diastereomers) | Idarubicinol (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (7S,9S)-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-Naphthacenedione; [7S-[7α, 9α, 9(R*)]]-7-[(3-amino-2, 3, 6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7, 8, 9, 10-tetrahydro-6, 9, 11-trihydroxy-9-(1-hydroxyethyl)-5, 12-Naphthacenedione; 13-Dihydroidarubicin; 4-Demethoxydaunorubicino l; Antibiotic FCE 22723. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H29NO9, Molecular Weight: 499.51. US Biological Life Sciences. |  Worldwide |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grade: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Idasanutlin | Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Synonyms: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grade: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. | |
| Idasanutlin | Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC 50 of 6 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7388. CAS No. 1229705-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15676. |  |
| Idazoxan | Idazoxan is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, and alpha2-adrenoceptor antagonist used in trials studying the basic science of molecular imaging, Alzheimer's disease, and major depressive disorder. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-; 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; 2-Imidazoline, 2-(1,4-benzodioxan-2-yl)-; (±)-Idazoxan; dl-Idazoxan; Racemic idazoxan. Grade: 95%. CAS No. 79944-58-4. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
| Idazoxan | Idazoxan. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Idazoxan;IDAZOXAN,99%;2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole;dl-Idazoxan;2-(1-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin;2-(2-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin;Idezoxane;RX-781094. Product Category: Heterocyclic Organic Compound. CAS No. 79944-58-4. Molecular formula: C11H12N2O2. Mole weight: 204.23. Product ID: ACM79944584. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Idazoxan hydrochloride | Idazoxan hydrochloride is the hydrochloride salt of idazoxan, which is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, as well as an alpha2-adrenoceptor antagonist. It is selective for α2- over α1-receptors. It is useful for the treatment of parkinsonian and schizophrenia. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1); 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride; (±)-Idazoxan monohydrochloride; 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; RX 781094; RX 781094A. Grade: ≥98%. CAS No. 79944-56-2. Molecular formula: C11H13ClN2O2. Mole weight: 240.69. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-CHLORO-5-FLUOROBENZYL CHLORIDE. Product Category: Heterocyclic Organic Compound. CAS No. 79944-65-2. Molecular formula: C7H5Cl2F. Mole weight: 179.019. Purity: 0.96. IUPACName: 1-Chloro-3-(chloromethyl)-5-fluorobenzene. Product ID: ACM79944652. Alfa Chemistry ISO 9001:2015 Certified. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 79944-56-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Idazoxan hydrochloride | Idazoxan hydrochloride (RX 781094 hydrochloride) is an α 2 -adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinsons disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RX 781094 hydrochloride. CAS No. 79944-56-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-14561A. | |
| Idazoxan Hydrochloride (2-(1,4-Benzodioxan-2-yl)-2-imidazoline Hydrochloride, RX781094, Idazoxa, a2-Adrenoceptor Antagonist, Idazoxan Hydrochloride) | A non-selective antagonist for alpha-2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for alpha-2A, alpha-2B, and alpha-2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 79944-56-2. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| IDE1 | IDE1 is an inducer of definitive endoderm 1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160927-48-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100533. | |
| IDE-1 (1- [2- [ (2-Carboxyphenyl) methylene] hydrazide] heptanoic acid) | Cell-permeable. Directs differentiation of embryonic stem cells (ESCs) into the endodermal lineage (EC??=125nm). Nodal/Smad signaling is activated indicating IDE-1 functions via TGF-b-signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 1160927-48-9. Pack Sizes: 1mg, 5mg . US Biological Life Sciences. | Worldwide |
| IDE1 (1DE 1, Inducer of Definitive Endoderm 1) | IDE1 (1DE 1, Inducer of Definitive Endoderm 1). Group: Biochemicals. Alternative Names: 1-[2-[ (2-carboxyphenyl) methylene]hydrazide]-heptanedioic acid. Grades: Highly Purified. CAS No. 1160927-48-9. Pack Sizes: 10mg. Molecular Formula: C15 H18 N2O5, Molecular Weight: 306.3. US Biological Life Sciences. | Worldwide |
| IDE 2 | IDE2 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1136466-93-7. Pack Sizes: 1 mg. Product ID: HY-100534. | |
| IDE2 (1DE 2, Inducer of Definitive Endoderm 2) | IDE2 (1DE 2, Inducer of Definitive Endoderm 2). Group: Biochemicals. Alternative Names: Heptanedioic acid-1- (2-cyclopentylidene hydrazide) . Grades: Highly Purified. CAS No. 1136466-93-7. Pack Sizes: 10mg. Molecular Formula: C12 H20 N2O3, Molecular Weight: 240.3. US Biological Life Sciences. | Worldwide |
| Idebenone | analytical standard. Group: Additional drugsphytochemicals. |  |
| Idebenone | Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC 50 =16.65 μM) [1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells [2]. Idebenone quickly crosses the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. CAS No. 58186-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0303. | |
| Idebenone | Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; Avan; CV 2619; Daruma; Idebenone; Mnesis. Grades: Highly Purified. CAS No. 58186-27-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Idebenone | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Synonyms: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. Grade: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44. | |
| Idebenone > 98% | Idebenone > 98%. CAS No. 58186-27-9. |  CA, FL & NJ |
| Idebenone-d6 | Idebenone-d6 is a labelled Idebenone. Idebenone is a synthetic analogue of coenzyme Q10. It is indicated for the treatment of Alzheimer's disease. Synonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione-d6. Grade: > 95%. Molecular formula: C19H24O5D6. Mole weight: 344.48. | |
| Idebenone-D-Glucuronide | Idebenone-D-Glucuronide is a compound used for studying neurodegenerative ailments, most notably Alzheimer's and Parkinson's. Grade: > 95%. Molecular formula: C25H38O11. Mole weight: 514.58. | |
| Idebenone Glucuronide | Idebenone Glucuronide is the glucuronoside conjugate of Idebenone, an ubiquinone derivative with protective effects against cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid; Avan Glucuronide; CV 2619 Glucuronide; Daruma Glucuronide; Mnesis Glucuronide; Idebenone β-D-Glucuronide. Molecular formula: C25H38O11. Mole weight: 514.56. | |
| Idebenone Glucuronide-13C,d3 | The isotope-labelled idebenone glucuronide is a glucuronide conjugate of idebenone. Idebenone is a ubiquinone derivative with protective effects on cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Molecular formula: C24[13C]H35D3O11. Mole weight: 518.57. | |
| Idebenone Glucuronide-13C,d3 | Idebenone Glucuronide-13C,d3. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2413CH35D3O11, Molecular Weight: 518.57. US Biological Life Sciences. | Worldwide |
| Idebenone Impurity8 | Idebenone Impurity8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104967-07-9. Molecular formula: C22H34O6. Mole weight: 294.51. Catalog: APB104967079. | |
| Idebenone Impurity9 | Idebenone Impurity9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104966-92-9. Molecular formula: C21H32O6. Mole weight: 380.48. Catalog: APB104966929. | |
| Idebenone Sulfate | Idebenone Sulfate is a potent biomedical product used to study the progression of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. It exhibits antioxidant and neuroprotective properties. Synonyms: 10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl hydrogen sulfate; 319906-76-8. Grade: > 95%. CAS No. 319906-76-8. Molecular formula: C19H30O8S. Mole weight: 418.51. | |
| Idebenone Sulfate-13C,d3 Potassium Salt | Idebenone Sulfate-13C,d3 Potassium Salt. Group: Biochemicals. Alternative Names: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1813CH26D3KO8S, Molecular Weight: 460.6. US Biological Life Sciences. | Worldwide |
| Idebenone Sulfate-13C,d3 Potassium Salt | Isotope labelled Idebenone Sulfate is an analogue of Idebenone. It is an ubiquinone derivative with protective effects against cerebral ischemia. Idebenone Sulfate can be used for skin protection and regenerative purposes. Synonyms: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Molecular formula: C18[13C]H26D3KO8S. Mole weight: 460.6. | |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grade: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. | |
| Idelalisib | Idelalisib (CAL-101; GS-1101) is a highly selective and orally bioavailable p110δ inhibitor with an IC 50 of 2.5 nM, showing 40- to 300-fold selectivity for p110δ over other PI3K class I enzymes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAL-101; GS-1101. CAS No. 870281-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13026. | |
| Idelalisib-[d5] | Idelalisib-[d5] is the labelled analogue of Idelalisib. Idelalisib is a chemotherapy drug used for the treatment of relapsed chronic lymphocytic leukemia (CLL), follicular B-cell non-Hodgkin lymphoma and small lymphocytic lymphoma (SLL). Synonyms: Idelalisib D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1830330-31-8. Molecular formula: C22H13D5FN7O. Mole weight: 420.45. | |
| Idelalisib Metabolit | Idelalisib Metabolite is a metabolite of Idelalisib, a drug primarily employed in the treatment of chronic lymphocytic leukemia and follicular lymphoma. Synonyms: GS-563117. Grade: > 95%. Molecular formula: C22H18FN7O2. Mole weight: 431.43. | |
| Idelalisib Metabolit-d5 | Idelalisib Metabolit-d5. Grade: > 95%. Molecular formula: C22H13FN7O2D5. Mole weight: 436.46. | |
| Idelalisib N-Glucuronide | Idelalisib N-Glucuronide is an exclusive metabolite of Idelalisib, a prominent therapeutic agent for chronic lymphocytic leukemia (CLL), follicular lymphoma, and small lymphocytic lymphoma, exhibiting its efficacious function as a precise and strategic kinase inhibitor. Grade: > 95%. Molecular formula: C28H27FN7O7. Mole weight: 592.57. | |
| IDF-11774 | IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. Study showed that IDF-11774 inhibited the accumulation of HIF-1α in vitro and in vivo in colorectal carcinoma HCT116 cells under hypoxic conditions, suppressing angiogenesis of cancer cells by reducing the expression of HIF-1 target genes. Synonyms: EX-A3002; 2-[4-(1-adamantyl)phenoxy]-1-(4-methylpiperazin-1-yl)ethanone. CAS No. 1429054-28-3. Molecular formula: C23H32N2O2. Mole weight: 368.51. | |
| IDF-11774 | IDF-11774 is a novel hypoxia-inducible factor ? (HIF?)-1 inhibitor with an IC50 of 3.65??M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1429054-28-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-111387. | |
| IDFP | IDFP is an organophosphorus compound that acts as an irreversible inhibitor of MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively. Inhibition of MAGL and FAAH increases anandamide and 2-AG in the brain, resulting in increased cannabinoid signaling and typical cannabinoid behavioral effects in animal studies. Synonyms: Isopropyl Dodecylfluorophosphonate; 1-[fluoro(propan-2-yloxy)phosphoryl]dodecane. Grade: ≥98%. CAS No. 615250-02-7. Molecular formula: C15H32FO2P. Mole weight: 294.4. | |
| IDH1 Inhibitor 8 | IDH1 Inhibitor 8 is an isocitrate dehydrogenase 1 (IDH1) inhibitor that can be used in cancer research. Synonyms: AG-120 Racemate; AG-120 (racemic); Ivosidenib (racemic); 1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide. Grade: 98%. CAS No. 1448346-63-1. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.97. | |
| IDH305 | IDH305 is a potent, selective and brain penetrant inhibitor of mutant isocitrate dehydrogenase 1 (IDH1; IC50s = 27, 28, and 6,140 nM for recombinant IDH1R132H, IDH1R132C, and wild-type IDH1, respectively). It suppresses mutant IDH1-dependent 2-HG production and cell proliferation, and exhibits antitumor activity in preclinical studies. Synonyms: (4R)-4-[(1S)-1-fluoroethyl]-3-[2-({(1S)-1-[4-methyl-2'-(trifluoromethyl)[3,4'-bipyridin]-6-yl]ethyl}amino)pyrimidin-4-yl]-1,3-oxazolidin-2-one. Grade: ≥98%. CAS No. 1628805-46-8. Molecular formula: C23H22F4N6O2. Mole weight: 490.45. | |
| IDIC | IDIC. Uses: Designed for use in research and industrial production. Product Category: Organic Photovoltaic (OPV). CAS No. 1883441-92-6. Product ID: ACM1883441926. Alfa Chemistry ISO 9001:2015 Certified. | |
| IDN-1965 | IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective at inhibiting Fas-mediated apoptosis by multiple routes of administration. The therapeutic potential of caspase inhibitors appears promising for the treatment of apoptosis-mediated liver injury based on potency and postinsult efficacy. Synonyms: IDN1965; IDN 1965; N-[(1,3-Dimethylindole-2-Carbonyl)Valinyl]-3-Amino-4-Oxo-5-Fluoropentanoic Acid; 3-((S)-2-(1,3-dimethyl-1H-indole-2-carboxamido)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid. Grade: 98%. CAS No. 204919-14-2. Molecular formula: C21H26FN3O5. Mole weight: 419.45. | |
| IDO1 and HDAC1 Inhibitor | IDO1 and HDAC1 Inhibitor is a dual inhibitor of IDO1 and HDAC1 with IC50s of 69.0 nM and 66.5 nM, respectively. Synonyms: N-(2-Aminophenyl)-N'-[2-({4-[N-(3-bromo-4-fluorophenyl)-N'-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}amino)ethyl]terephthalamide; 1,4-Benzenedicarboxamide, N1-(2-aminophenyl)-N4-[2-[[4-[(E)-[(3-bromo-4-fluorophenyl)amino](hydroxyimino)methyl]-1,2,5-oxadiazol-3-yl]amino]ethyl]-. CAS No. 2227044-16-6. Molecular formula: C25H22BrFN8O4. Mole weight: 597.40. | |
| IDO1-IN-19 | IDO1-IN-19 (Compound 17) is an orally active IDO1 inhibitor with an IC 50 of CYP2C9 of 8.64 μM. IDO1-IN-19 also acts funciton on cardiac channels, with IC 50 s of 12 μM ( IKr ), 40 μM ( INa ), 8.3 μM ( ICa ), respectively. IDO1-IN-19 has the potential to study cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2328099-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144652. | |
| IDO-IN-1 | An IDO inhibitor with IC50 of 59 nM, showing activity in Hela cell (IC50 = 12 nM). Synonyms: IDO-IN-1; IDO-IN1; IDO-IN 1. Grade: > 98%. CAS No. 914638-30-5. Molecular formula: C9H7BrFN5O2. Mole weight: 316.09. | |
| IDO-IN-12 | IDO-IN-12 is an indoleamine 2,3-dioxygenase ( IDO ) inhibitor extracted from patent WO 2017181849 A1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1888341-29-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115122. | |
| IDO-IN-13 | IDO-IN-13 is an IDO1 inhibitor with EC50 of 17 nM. Grade: 98% by HPLC. CAS No. 2291164-02-6. Molecular formula: C26H17F3N4O. Mole weight: 458.4. | |
| IDO-IN-2 | IDO-IN-2 is a potent inhibitor of IDO (indoleamine-(2,3)-dioxygenase) with IC50 of 3 nM. Synonyms: IDO inhibitor 1; 1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)urea. CAS No. 1668565-74-9. Molecular formula: C29H35N7O. Mole weight: 497.63. | |
| IDO-IN-3 | A potent IDO inhibitor. Synonyms: IDO-IN-3; IDO-IN3; IDO-IN 3. Grade: > 98%. CAS No. 2070018-30-1. Molecular formula: C11H12BrFN6O2. Mole weight: 359.15. | |
| IDO-IN-4 | A potent IDO1 inhibitor with IC50 of 8 nM in human IDO1/HEK293 cells. Synonyms: IDO-IN-4; IDO-IN4; IDO-IN 4.(1R,2S)-2-(4-(diisobutylamino)-3-(3-(p-tolyl)ureido)phenyl)cyclopropanecarboxylic acid. Grade: > 98%. CAS No. 1629125-65-0. Molecular formula: C26H35N3O3. Mole weight: 437.57. | |
| IDO-IN-5 | A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-5; IDO-IN5; IDO-IN 5.(1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-79-9. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-6 | A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-6; IDO-IN6; IDO-IN 6.(1S,4r)-4-((S)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-76-6. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-7 | A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-7; IDO-IN7; IDO-IN 7.(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-78-8. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-8 | A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-8; IDO-IN8; IDO-IN 8.(1S,4r)-4-((S)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-77-7. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDOR-4 | IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2839901-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-158002. | |
| Idoxanthin | Idoxanthin. Group: Biochemicals. Alternative Names: (3RS,3'RS,4'RS)-Trihydroxy-b,b-caroten-4-one. Grades: Highly Purified. CAS No. 25510-19-4. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C40H54O4. US Biological Life Sciences. | Worldwide |
| Idoxifene | Idoxifene (CB7432) is a novel tissue-specific selective estrogen receptor modulator ( SERM ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB7432. CAS No. 116057-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00178. | |
| Idoxifene | Idoxifene is a non-steroidal estrogen antagonist. It is also structurally analogous to tamoxifen. Idoxifene was both active and well tolerated in postmenopausal women with metastatic breast cancer. Idoxifene had similar efficacy and toxicity to tamoxifen in this randomized comparison. Synonyms: CB7432; 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-pyrrolidine; trans-1-(4-Iodophenyl)-1-(4-(2'-pyrrolidinoethoxy)phenyl)-2-phenylbutene; (E)-1-[2-[4-[1-(4-iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]-pyrrolidine; SB 223030. Grade: ≥95%. CAS No. 116057-75-1. Molecular formula: C28H30INO. Mole weight: 523.45. | |
| Idoxuridine | Idoxuridine (5-Iodo-2-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC 50 value of 4.3 μM [1]. Idoxuridine shows anti-orthopoxvirus activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Iodo-2-deoxyuridine; 5-IUdR; IdUrd. CAS No. 54-42-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0307. | |
| Idoxuridine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Idoxuridine. | |
| Idoxuridine | 5-Iodo-2'-deoxyuridine is a nucleoside analog that can be incorporated into viral DNA replication to treat herpes simplex keratitis. Uses: 5-iodo-2'-deoxyuridine is a nucleoside analog treat herpes simplex keratitis. Synonyms: 5-Iodo-2'-deoxyuridine; IDU; 2'-Deoxy-5-iodouridine; 5-Iodo-2'-deoxy-D-uridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; IUdR; Dendrid; Emanil; NSC 39661; Ophthalmadine; Herpesil; Herpidu; Herplex; Stoxil; Stoxip; Synmiol; Virudox. Grade: ≥98% by HPLC. CAS No. 54-42-2. Molecular formula: C9H11IN2O5. Mole weight: 354.10. | |
| Idoxuridine (2-Deoxy-5-iodouridine, IdU, IUdR, Dendrid, Emanil) | Used as an antiviral. Group: Biochemicals. Alternative Names: 2-Deoxy-5-iodouridine, IdU, IUdR, Dendrid, Emanil. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| IDP TEA salt | IDP TEA salt is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Synonyms: Inosine-5'-diphosphate, triethylammonium salt; Inosine 5'-(trihydrogen diphosphate), triethylammonium salt (1:x); Inosine 5'-(trihydrogen diphosphate), triethylammonium salt; 5'-IDP triethylammonium salt; Inosine 5-diphosphate triethylammonium salt; Inosine diphosphate triethylammonium salt. Grade: ≥95% by HPLC. Molecular formula: C10H14N4O11P2 (free acid). Mole weight: 428.18 (free acid). | |
| Idr-1 | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK8F0240, 940291-10-1. Product Category: Inhibitors. Appearance: Solid. CAS No. 940291-10-1. Molecular formula: C65H118N18O15. Mole weight: 242.314680 [g/mol]. Purity: 0.96. IUPACName: (2S)-1-formyl-N-[(2S)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide;propane. Canonical SMILES: CCC.CC(C=O)NC(=O)C1CCCN1C=O. Product ID: ACM940291101. Alfa Chemistry ISO 9001:2015 Certified. Categories: IAR 99. | |
| IDR-1 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IDR-1 | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 940291-10-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2320. | |
| IDR-1 | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. CAS No. 940291-10-1. Molecular formula: C65H118N18O15. Mole weight: 242.31. | |
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