A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Synonyms: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50.
Ibrutinib-d4
Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective BrutonÂs tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences.
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Ibrutinib Dimer
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99.
Ibrutinib, Free Base
Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM in cellular assay with Ramos cells. It demonstrated preference toward BTK over closely related kinases, blocked B cell function and BTK-dependent processes, and demonstrated clear efficacy in a mouse arthritis model. Young P.R., et al. "Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase." ChemMedChem. 2: 58-61 (2007). Group: Biochemicals. Alternative Names: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one; Imbruvica. Grades: Purified. CAS No. 936563-96-1. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences.
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Ibrutinib Impurity 1
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58.
Ibrutinib Impurity 18
Ibrutinib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 1022150-12-4. Molecular Formula: C22H22N6O. Mole Weight: 386.45. Catalog: APB1022150124.
Ibrutinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 330786-24-8. Molecular Formula: C17H13N5O. Mole Weight: 303.32. Catalog: APB330786248.
Ibrutinib Impurity 8
Ibrutinib Impurity 8 is a useful synthetic intermediate in the synthesis of Ibrutinib, a highly selective Bruton's tyrosine kinase (BTK) irreversible inhibitor. Synonyms: 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine; 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-; Ibrutinib intermeidate N-2. Grades: ≥97% by HPLC. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.33.
Ibrutinib Impurity HNEJ
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C49H46N12O4. Mole weight: 866.99.
Ibrutinib Impurity IMYBJ
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C20H19N5O. Mole weight: 345.41.
Ibrutinib Impurity JXBJ
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C26H26N6O2. Mole weight: 454.53.
Ibrutinib Impurity MDDYH
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. CAS No. 2052279-49-7. Molecular formula: C25H24N6O3. Mole weight: 456.51.
Ibrutinib Impurity SMSJ
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C32H24N8O2. Mole weight: 552.60.
Ibrutinib Methoxy Impurity
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one; Ibrutinib impurity JYD. Grades: ≥95%. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55.
Ibudilast
Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Ibudilast
Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Synonyms: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grades: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31.
Ibudilast-d3 (Major)
Labeled Ibudilast. A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). Group: Biochemicals. Alternative Names: 2-Methyl-1-[2- (1-methylethyl) pyrazolo[1, 5-a]pyridin-3-yl]-1-propanone-d3; 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3; 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3; AV 411-d3; KC 404-d3; Ketas-d3. Grades: Highly Purified. CAS No. 102064-45-9. Pack Sizes: 1mg. US Biological Life Sciences.
Ibufenac is an analog of ibuprofen, and also acts as a COX inhibitor. Ibufenac can be used as an analgesic and anti-inflammatory agent but exhibits hepatotoxicity. Synonyms: Dytransin; Ibunac; 4-Isobutylphenylacetic acid; 2-[4-(2-methylpropyl)phenyl]acetic acid; NSC 99976. Grades: ≥95%. CAS No. 1553-60-2. Molecular formula: C12H16O2. Mole weight: 192.3.
Ibufenac
Ibufenac. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic acid; 4- (2-Methylpropyl) phenylacetic acid; 4-Isobutoxyphenylacetic acid. Grades: Highly Purified. CAS No. 1553-60-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H16O2. US Biological Life Sciences.
Used as an analgesic, anti-inflammatory. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic Acid, Dytransin, Ibunac. Grades: Highly Purified. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences.
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Ibufenac Ethyl Ester
Ibufenac Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Acetic acid, (p-isobutylphenyl)-, ethyl ester (7CI,8CI),4-(2-Methylpropyl)benzeneacetic acid ethyl ester, Ethyl p-isobutylphenylacetate, Ethyl (4-isobutylphenyl)acetate. CAS No. 15649-02-2. IUPAC Name: ethyl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular Formula: C14H20O2. Mole Weight: 220.31. Catalog: APS15649022. SMILES: CCOC(=O)Cc1ccc(CC(C)C)cc1. Format: Neat. Shipping: Room Temperature.
Ibufenac Isopropyl Ester
Ibufenac Isopropyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ibufenac Isopropyl Ester. IUPAC Name: propan-2-yl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular Formula: C15H22O2. Mole Weight: 234.33. Catalog: APS014285. SMILES: CC(C)Cc1ccc(CC(=O)OC(C)C)cc1. Format: Neat. Shipping: Room Temperature.
Ibufenac Methyl Ester
Ibufenac Methyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Methyl (4-isobutylphenyl)acetate, 2-(4-Isobutylphenyl)acetic acid methyl ester,4-(2-Methylpropyl)benzeneacetic acid methyl ester. CAS No. 61566-33-4. IUPAC Name: methyl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular Formula: C13H18O2. Mole Weight: 206.28. Catalog: APS61566334. SMILES: COC(=O)Cc1ccc(CC(C)C)cc1. Format: Neat. Shipping: Room Temperature.
Ibulocydine
Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and Cdk9/cyclin T. Ibulocydine inhibited the growth of HCC cells more effectively than other Cdk inhibitors, including olomoucine and roscovitine, whereas ibulocydine as well as the other Cdk inhibitors and BMK-Y101 minimally influenced the growth of normal hepatocyte cells. Ibulocydine induced apoptosis in HCC cells, most likely by inhibiting Cdk7 and Cdk9. In vitro treatment of HCC cells with ibulocydine rapidly blocked phosphorylation of the carboxyl-terminal domain (CTD) of the large subunit of RNA polymerase II, a process mediated by Cdk7/9. Anti-apoptotic gene products such as Mcl-1, survivin, and X-linked IAP (XIAP) are crucial for the survival of many cell types, including HCC. Following the inhibition of RNA polymerase II phosphorylation, ibulocydine caused rapid down-regulation of Mcl-1, survivin, and XIAP, thus inducing apoptosis. Furthermore, ibulocydine effectively induced apoptosis in HCC xenografts with no toxic side effects. These results suggest that ibulocydine is a strong candidate anti-cancer drug for the treatment of HCC. Synonyms: Ibulocydine. Grades: 98%. CAS No. 1314096-68-8. Molecular formula: C16H20BrN5O6. Mole weight: 458.26.
Ibuprofen
Ibuprofen. Group: Biochemicals. Alternative Names: Isobutyl propanoicphenolic acid; (RS) -2- (4- (2-Methylpropyl) phenyl) propanoic acid; Racemic ibuprofen. Grades: Highly Purified. CAS No. 15687-27-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H18O2. US Biological Life Sciences.
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Ibuprofen
Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Synonyms: α-methyl-4-(2-methylpropyl)?-benzeneacetic acid. CAS No. 15687-27-1. Molecular formula: C13H18O2. Mole weight: 206.28.
Ibuprofen
25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-25g. Molecular Weight 206.28. See USA prepack pricing.
Ibuprofen
100g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-100g. Molecular Weight 206.28. See USA prepack pricing.
Ibuprofen
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-1g. Molecular Weight 206.28. See USA prepack pricing.
Ibuprofen Acyl-beta-D- Glucuronide
Ibuprofen Acyl-beta-D-Glucuronide is an essential metabolite derived from ibuprofen, serving as a pivotal constituent in the synthesis of nonsteroidal anti-inflammatory drugs. Synonyms: Ibuprofen glucuronide; (2S, 3S, 4S, 5R, 6S) -3, 4, 5-Trihydroxy-6-[2- (4-Isobutylphenyl) Propanoyloxy]Tetrahydropyran-2-Carboxylic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-(4-Isobutylphenyl)-1-Oxopropoxy]-2-Tetrahydropyrancarboxylic Acid; Ibuprofen Acyl Glucuroni. Grades: > 95%. CAS No. 115075-59-7. Molecular formula: C19H26O8. Mole weight: 382.40.
Ibuprofen acyl-β-D-glucuronide(mixture of diastereomers)
Ibuprofen Carboxylic Acid is the major metabolite of Ibuprofen which may reduce the risk of cataracts by protecting lenticular enzymes. Synonyms: 4-(1-Carboxyethyl)-α-methyl-benzenepropanoic Acid; 2,4'-(2-Carboxypropyl)phenylpropionic Acid; Carboxyibuprofen; 3-[4-(1-Carboxyethyl)phenyl]-2-methylpropionic acid. Grades: > 95%. CAS No. 15935-54-3. Molecular formula: C13H16O4. Mole weight: 236.27.
Ibuprofen Carboxylic Acid-d3 (Mixture of Diastereomers)
The major labeled metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-α-methylbenzenepropanoic Acid-d3; 2, 4- (2-Carboxypropyl) phenylpropionic Acid-d3; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid-d3; Carboxyibuprofen-d3. Grades: Highly Purified. CAS No. 1216505-29-1. Pack Sizes: 1mg. US Biological Life Sciences.
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Ibuprofen Carboxylic Acid-d3(Mixture of Diastereomers)
The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-a-methyl-benzenepropanoic Acid; 2, 4- (2-Carboxypropyl) phenylpropionic Acid; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid; Carboxyibuprofen. Grades: Highly Purified. CAS No. 15935-54-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Ibuprofen EP Impurity A
Ibuprofen EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 66622-47-7. Molecular Formula: C13H18O2. Mole Weight: 206.29. Catalog: APB66622477.
Ibuprofen EP Impurity B
Ibuprofen EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3585-49-7. Molecular Formula: C13H18O2. Mole Weight: 206.29. Catalog: APB3585497.
Ibuprofen EP Impurity C
Ibuprofen EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59512-17-3. Molecular Formula: C13H19NO. Mole Weight: 205.3. Catalog: APB59512173.
Ibuprofen EP Impurity D
Ibuprofen EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 938-94-3. Molecular Formula: C10H12O2. Mole Weight: 164.2. Catalog: APB938943.
Ibuprofen EP Impurity E
Ibuprofen EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 38861-78-8. Molecular Formula: C12H16O. Mole Weight: 176.26. Catalog: APB38861788.
Ibuprofen EP Impurity F
Ibuprofen EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65322-85-2. Molecular Formula: C13H18O2. Mole Weight: 206.29. Catalog: APB65322852.
Ibuprofen EP Impurity G
Ibuprofen EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391054-15-1. Molecular Formula: C26H32O4. Mole Weight: 408.54. Catalog: APB1391054151.
Ibuprofen EP Impurity H
Ibuprofen EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2143535-25-3. Molecular Formula: C24H32O. Mole Weight: 336.52. Catalog: APB2143535253.
Ibuprofen EP Impurity I
Ibuprofen EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2143535-26-4. Molecular Formula: C24H34. Mole Weight: 322.53. Catalog: APB2143535264.
Ibuprofen EP Impurity J
Ibuprofen EP Impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65813-55-0. Molecular Formula: C13H16O3. Mole Weight: 220.27. Catalog: APB65813550.
Ibuprofen EP Impurity L
Ibuprofen EP Impurity L. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53949-53-4. Molecular Formula: C13H18O3. Mole Weight: 222.28. Catalog: APB53949534.
Ibuprofen EP Impurity M
Ibuprofen EP Impurity M. Uses: For analytical and research use. Group: Impurity standards. CAS No. 60057-62-7. Molecular Formula: C13H18O3. Mole Weight: 222.28. Catalog: APB60057627.
Ibuprofen EP Impurity N
Ibuprofen EP Impurity N. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3585-52-2. Molecular Formula: C11H14O2. Mole Weight: 178.23. Catalog: APB3585522.
Ibuprofen EP Impurity O
Ibuprofen EP Impurity O. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64451-76-9. Molecular Formula: C13H18O2. Mole Weight: 206.29. Catalog: APB64451769.
Ibuprofen EP Impurity P
Ibuprofen EP Impurity P. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36039-36-8. Molecular Formula: C13H20O. Mole Weight: 192.3. Catalog: APB36039368.
Ibuprofen EP Impurity Q
Ibuprofen EP Impurity Q. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36039-35-7. Molecular Formula: C12H18O. Mole Weight: 178.28. Catalog: APB36039357.