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| Product | Description | |
|---|---|---|
| I-BET 151 dihydrochloride | The hydrochloride salt form of I-BET 151, which has been found to be a BET bromodomain inhibitor and exhibit activities against human and murine MLL-fusion leukaemic cell lines. Synonyms: I-BET 151 dihydrochloride; I BET 151 dihydrochloride; IBET 151 dihydrochloride; IBET151 dihydrochloride; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1883545-47-8. Molecular formula: C23H21N5O3.2HCl. Mole weight: 488.37. |  |
| I-BET762 carboxylic acid | I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2. CAS No. 1300019-38-8. Molecular formula: C20H17ClN4O3. Mole weight: 396.83. | |
| Ibezapolstat | Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a K i of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACX-362E; GLS-362E. CAS No. 1275582-97-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128357. |  |
| Ibiglustat | Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat; SAR402671; GZ402671. CAS No. 1401090-53-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743. | |
| Ibiglustat | Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. In Oct 2016, Genzyme completed a phase II trial in Fabry's disease (Treatment-naïve) in USA, Czech Republic, France, Poland, Russia and the UK. Phase-II clinical trials in Gaucher's disease in USA is on-going. Uses: Fabry's disease; gaucher's disease. Synonyms: GZ-402671; GZ402671; GZ 402671; SSAR402671; SAR-402671; SAR 402671; Genz-682452-AA; Ibiglustat; GZ-452; Genz-682452; GZ 452; Genz 682452; GZ452; Genz682452; (3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1,3-thiazol-4-yl]propan-2-yl}carbamate. Grades: 98%. CAS No. 1401090-53-6. Molecular formula: C20H24FN3O2S. Mole weight: 389.49. | |
| Ibiglustat succinate | Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat succinate can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat succinate; SAR402671 succinate; GZ402671 succinate. CAS No. 1629063-80-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743B. | |
| Ibipinabant | Ibipinabant is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2), respectively. Uses: Cannabinoid receptor cb1 antagonists. Synonyms: BMS-646256; BMS646256; BMS 646256; SLV-319; SLV 319; SLV319; JD-5001; JD 5001; JD5001; Ibipinabant.3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4S-phenyl-1H-pyrazole-1-carboximidamide. Grades: ≥98%. CAS No. 464213-10-3. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.40. | |
| IBMX | IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grades: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24. | |
| IBMX | IBMX Inhibitor. Uses: Scientific use. Product Category: T1713. CAS No. 28822-58-4. |  |
| IBMX | IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| IBMX (3-Isobutyl-1-methylxanthine) | 3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3) | Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. Group: Biochemicals. Alternative Names: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Ibodutant | Ibodutant is a tachykinin receptor antagonist. It selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. It is a candidate drug for irritable bowel syndrome diarrhea. It was developed by The Menarini Group. It is in the clinical phase III. Uses: Ibodutant is a candidate drug for irritable bowel syndrome diarrhea. Synonyms: MEN-15596; MEN 15596; MEN15596; Ibodutant 6-Methyl-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide;(R)-6-methyl-N-(1-((1-oxo-3-phenyl-1-(((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidi. Grades: 98%. CAS No. 522664-63-7. Molecular formula: C37H48N4O4S. Mole weight: 644.87. | |
| I-BOP | I-BOP is a potent TP receptor agonist that induces platelet aggregation and vascular smooth muscle contraction. Synonyms: (Z)-7-[(1S,2R,3R,4R)-3-[(E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥95%. CAS No. 128719-90-4. Molecular formula: C23H29IO5. Mole weight: 512.4. | |
| Ibopamine Hydrochloride | Ibopamine Hydrochloride, the prodrug of epinine, is a sympathomimetic drug used in ophthalmology. It induces mydriasis. It acts as an agonist on Dopamine receptor D1 and α-adrenergic receptors and has been studied for the treatment of congestive heart failure. Synonyms: 2-Methylpropanoic Acid 1,1'-[4-[2-(Methylamino)ethyl]-1,2-phenylene] Ester Hydrochloride; 3,4-Di-O-isobutyrylepinine Hydrochloride; Inopamil; Scandine. Grades: ≥95%. CAS No. 75011-65-3. Molecular formula: C17H26ClNO4. Mole weight: 343.85. | |
| Ibotenic acid | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate ( NMDA ) and trans-ACPD or metabolotropic quisqualate (Q m ) receptor sites. Uses: Scientific research. Group: Natural products. Alternative Names: (RS)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2311. | |
| Ibotenic acid | 1mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C5H6N2O4. CAS No. 2552-55-8. Prepack ID 80949608-1mg. Molecular Weight 158.11. See USA prepack pricing. |  |
| Ibotenic acid | Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. Synonyms: (+/-)-Ibotenic acid; DL-Ibotenic acid. Grades: ≥98% by HPLC. CAS No. 2552-55-8. Molecular formula: C5H6N2O4. Mole weight: 158.11. | |
| Ibotenic Acid | Ibotenic acid is a conformationally restricted analog of glutamic acid and a a potent Glu agonist.A highly potent agonist ofnMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts. Group: Biochemicals. Alternative Names: a-Amino-3-hydroxy-5-isoxazoleacetic acid;; (2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid; Glutamate Receptor Agonist; NSC 204850. Grades: Highly Purified. CAS No. 2552-55-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C?H?N?O?, Molecular Weight: 158.11. US Biological Life Sciences. | Worldwide |
| iBRD4-BD1 | iBRD4-BD1 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 has inhibition activity for BRD4 bromodomain with an IC 50 value of 12 nM. iBRD4-BD1 can be used for the research of inflammation and oncology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2839318-17-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151594. | |
| I-BRD9 | I-BRD9, as a selective cell active chemical probe for BRD9 (pIC50 = 7.3), it exhibits 200-fold selectivity for bromodomain containing protein 9 over the highly homologous BRD7 bromodomain, >70-fold selectivity for BRD9 over a panel of 34 other bromodomain. Synonyms: N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamideI-BRD9; I-BRD-9; I-BRD 9N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamideG. CAS No. 1714146-59-4. Molecular formula: C22H22F3N3O3S2. Mole weight: 497.55. | |
| Ibrexafungerp | Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aR, 14R, 15R)-. Grades: ≥95%. CAS No. 1207753-03-4. Molecular formula: C44H67N5O4. Mole weight: 730.03. | |
| Ibrexafungerp | Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 3118; SCY-078. CAS No. 1207753-03-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-107126. | |
| Ibrexafungerp citrate | Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 3118 citrate; SCY-078 citrate. CAS No. 1965291-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107126A. | |
| Ibrexafungerp Citrate | Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aR, 14R, 15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). CAS No. 1965291-08-0. Molecular formula: C50H75N5O11. Mole weight: 922.17. | |
| Ibrolipim | Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL) -promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NO-1886. CAS No. 133208-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117549. | |
| Ibrutinib | Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC 50 of 0.5 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCI-32765. CAS No. 936563-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10997. | |
| Ibrutinib | Ibrutinib Inhibitor. Uses: Scientific use. Product Category: T1835. CAS No. 936563-96-1. | |
| Ibrutinib | Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Synonyms: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
| Ibrutinib-d4 | Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective BrutonÂs tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences. | Worldwide |
| Ibrutinib deacryloylpiperidine | Ibrutinib deacryloylpiperidine (IBT4A) is an impurity of Ibrutinib [1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC 50 of 0.5 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IBT4A. CAS No. 330786-24-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-78727. | |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
| Ibrutinib, Free Base | Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM in cellular assay with Ramos cells. It demonstrated preference toward BTK over closely related kinases, blocked B cell function and BTK-dependent processes, and demonstrated clear efficacy in a mouse arthritis model. Young P.R., et al. "Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase." ChemMedChem. 2: 58-61 (2007). Group: Biochemicals. Alternative Names: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one; Imbruvica. Grades: Purified. CAS No. 936563-96-1. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
| Ibrutinib Impurity 18 | Ibrutinib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 1022150-12-4. Molecular Formula: C22H22N6O. Mole Weight: 386.45. Catalog: APB1022150124. |  |
| Ibrutinib Impurity 2 | Grades: > 95%. Molecular formula: C28H26N6O3. Mole weight: 494.56. | |
| Ibrutinib impurity 20 | Ibrutinib impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1839090-60-6. Molecular Formula: C25H24N6O4. Mole Weight: 472.51. Catalog: APB1839090606. | |
| Ibrutinib impurity 22 | Ibrutinib impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2031255-26-0. Molecular Formula: C26H28N6O3. Mole Weight: 472.55. Catalog: APB2031255260. | |
| Ibrutinib Impurity 23 | Ibrutinib Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1838132-94-7. Molecular Formula: C25H26N6O3. Mole Weight: 458.52. Catalog: APB1838132947. | |
| Ibrutinib Impurity 24 | Ibrutinib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2437254-47-0. Molecular Formula: C25H24N6O3. Mole Weight: 456.51. Catalog: APB2437254470. | |
| Ibrutinib Impurity 3 | Synonyms: PCI-45227. Grades: > 95%. CAS No. 1226872-27-0. Molecular formula: C25H26N6O4. Mole weight: 474.52. | |
| Ibrutinib Impurity 31 | Ibrutinib Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethanone. CAS No. 1288338-95-3. Molecular Formula: C24H24N6O2. Mole Weight: 428.49. Catalog: APB1288338953. | |
| Ibrutinib Impurity 4 | Grades: > 95%. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
| Ibrutinib Impurity 5 | Ibrutinib Impurity 5 is an impurity in commercial preparation of Ibrutinib. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. Grades: > 95%. Molecular formula: C25H25ClN6O2. Mole weight: 476.97. | |
| Ibrutinib Impurity 5 | Ibrutinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. CAS No. 1288338-96-4. Molecular Formula: C25H25ClN6O2. Mole Weight: 476.96. Catalog: APB1288338964. | |
| Ibrutinib Impurity 6 | Synonyms: Ibrutinib impurity 6; 1987905-93-0; ZPJ4HT8UNA; UNII-ZPJ4HT8UNA; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one (Imatinib Impurity); 1-Propanone, 1,3-bis((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-; 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-1-[(3R)-3-[4-imino-3-(4-phenoxyphenyl)-1H,2H,4H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one;1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one? (Imatinib Impurity; Ibrutinib Addition Adduct with (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl). Grades: > 95%. Molecular formula: C47H46N12O3. Mole weight: 826.97. | |
| Ibrutinib Impurity 8 | Ibrutinib Impurity 8 is a useful synthetic intermediate in the synthesis of Ibrutinib, a highly selective Bruton's tyrosine kinase (BTK) irreversible inhibitor. Synonyms: 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine; 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-; Ibrutinib intermeidate N-2. Grades: ≥97% by HPLC. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.33. | |
| Ibrutinib Impurity 8 | Ibrutinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 330786-24-8. Molecular Formula: C17H13N5O. Mole Weight: 303.32. Catalog: APB330786248. | |
| Ibrutinib Impurity HNEJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C49H46N12O4. Mole weight: 866.99. | |
| Ibrutinib Impurity IMYBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C20H19N5O. Mole weight: 345.41. | |
| Ibrutinib Impurity JXBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C26H26N6O2. Mole weight: 454.53. | |
| Ibrutinib Impurity MDDYH | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. CAS No. 2052279-49-7. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
| Ibrutinib Impurity SMSJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C32H24N8O2. Mole weight: 552.60. | |
| Ibrutinib Methoxy Impurity | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one; Ibrutinib impurity JYD. Grades: ≥95%. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. | |
| Ibrutinib Racemate | Ibrutinib Racemate (PCI-32765 Racemate) is the racemate of Ibrutinib. Ibrutinib is a selective, irreversible Btk inhibitor with IC 50 value of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCI-32765 Racemate. CAS No. 936563-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10997A. | |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Synonyms: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grades: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31. | |
| Ibudilast | Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase ( PDE ) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KC-404; AV-411; MN-166. CAS No. 50847-11-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0763. | |
| Ibudilast | Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ibudilast-d3 (Major) | 2H Labeled Compounds. CAS No. 102064-45-9. Molecular formula: C14H15D3N2O. Mole weight: 233.32. Catalog: ACM102064459. |  |
| Ibudilast-d3 (Major) | Labeled Ibudilast. A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). Group: Biochemicals. Alternative Names: 2-Methyl-1-[2- (1-methylethyl) pyrazolo[1, 5-a]pyridin-3-yl]-1-propanone-d3; 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3; 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3; AV 411-d3; KC 404-d3; Ketas-d3. Grades: Highly Purified. CAS No. 102064-45-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ibudilast impurity 1 | Ibudilast impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2713301-45-0. Molecular Formula: C14H11D7N2O. Mole Weight: 237.35. Catalog: APB2713301450. | |
| Ibudilast impurity 2 | Ibudilast impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101162-42-9. Molecular Formula: C14H20N2O3. Mole Weight: 264.33. Catalog: APB101162429. | |
| Ibudilast impurity 4 | Ibudilast impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102064-45-9. Molecular Formula: C14H14D4N2O. Mole Weight: 234.34. Catalog: APB102064459. | |
| IBU-DMT-DEOXYGUANOSINE H-PHOSPHONATE*TRI ETHYLAMMONI | Heterocyclic Organic Compound. CAS No. 110237-99-5. Molecular formula: C35H37N5O9P. Mole weight: 702.67. Purity: 0.96. IUPACName: -. Catalog: ACM110237995. | |
| Ibufenac | Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dytransin. CAS No. 1553-60-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W040672. | |
| Ibufenac | Ibufenac. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic acid; 4- (2-Methylpropyl) phenylacetic acid; 4-Isobutoxyphenylacetic acid. Grades: Highly Purified. CAS No. 1553-60-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H16O2. US Biological Life Sciences. | Worldwide |
| Ibufenac | Ibufenac is an analog of ibuprofen, and also acts as a COX inhibitor. Ibufenac can be used as an analgesic and anti-inflammatory agent but exhibits hepatotoxicity. Synonyms: Dytransin; Ibunac; 4-Isobutylphenylacetic acid; 2-[4-(2-methylpropyl)phenyl]acetic acid; NSC 99976. Grades: ≥95%. CAS No. 1553-60-2. Molecular formula: C12H16O2. Mole weight: 192.3. | |
| Ibufenac (4- (2-Methylpropyl) benzeneacetic Acid, Dytransin, Ibunac) | Used as an analgesic, anti-inflammatory. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic Acid, Dytransin, Ibunac. Grades: Highly Purified. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ibufenac Ethyl Ester | Ibufenac Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Acetic acid, (p-isobutylphenyl)-, ethyl ester (7CI,8CI),4-(2-Methylpropyl)benzeneacetic acid ethyl ester, Ethyl p-isobutylphenylacetate, Ethyl (4-isobutylphenyl)acetate. CAS No. 15649-02-2. IUPAC Name: ethyl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular Formula: C14H20O2. Mole Weight: 220.31. Catalog: APS15649022. SMILES: CCOC(=O)Cc1ccc(CC(C)C)cc1. Format: Neat. Shipping: Room Temperature. | |
| Ibufenac Isopropyl Ester | Ibufenac Isopropyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ibufenac Isopropyl Ester. IUPAC Name: propan-2-yl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular Formula: C15H22O2. Mole Weight: 234.33. Catalog: APS014285. SMILES: CC(C)Cc1ccc(CC(=O)OC(C)C)cc1. Format: Neat. Shipping: Room Temperature. | |
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