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| Product | Description | |
|---|---|---|
| KCN1 | KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF reporter gene activity in several glioma cell lines at the nanomolar level. KCN1 also downregulated transcription of endogenous HIF-1 target genes, such as VEGF, Glut-1, and carbonic anhydrase 9, in a hypoxia-responsive element (HRE)-dependent manner. KCN1 potently inhibited the growth of subcutaneous malignant glioma tumor xenografts with minimal adverse effects on the host. Mechanistically, KCN1 did not downregulate the levels of HIF-1α or other components of the HIF transcriptional complex; rather, it antagonized hypoxia-inducible transcription by disrupting the interaction of HIF-1α with transcriptional coactivators p300/CBP.CONCLUSIONS: The new HIF pathway inhibitor KCN1 has antitumor activity in mouse models, supporting its further translation for the treatment of human tumors displaying hypoxia or HIF overexpression. Synonyms: KCN-1; 3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide. CAS No. 927823-01-6. Molecular formula: C26H27NO5S. Mole weight: 465.561. |  |
| KD025 | KD025 is an orally available and selective ROCK2 inhibitor with IC50 value of 60 nM and Ki value of 41 nm, respectively. It was shown to suppress adipogenesis in human adipose-derived stem cells. Uses: Protein kinase inhibitors. Synonyms: SLx 2119; SLx2119; KD-025; 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide. Grades: >98%. CAS No. 911417-87-3. Molecular formula: C26H24N6O2. Mole weight: 452.51. | |
| K-(D-1-Nal)-FwLL-NH2 | K-(D-1-Nal)-FwLL-NH2 is a potent and high affinity inverse ghrelin receptor inverse agonist. Its Ki values are 31 and 4.9 nM in HEK293T and COS7 cells respectively. It blocks ghrelin receptor-mediated G13- and Gq-dependent signaling pathways. Synonyms: L-Lysyl-3-(1-naphthalenyl)-D-alanyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide; K-(D-1-Nal)-FwLL-NH2; K (D 1 Nal) FwLL NH2. Grades: >98%. CAS No. 1394288-22-2. Molecular formula: C51H67N9O6. Mole weight: 902.13. | |
| KD 5170 | KD 5170 is a mercaptoketone-based histone deacetylase (HDAC) inhibitor displaying antitumor activity in vitro and in vivo. It exhibits broad spectrum antitumor activity in vitro and in vivo. Synonyms: S- (2- (6- (4- (3- (Dimethylamino) propoxy) phenylsulfonamido) pyridin-3-yl) -2-oxoethyl) ethanethioate. Grades: ≥98%. CAS No. 940943-37-3. Molecular formula: C20H25N3O5S2. Mole weight: 451.6. | |
| KD 5170 | KD 5170. Group: Biochemicals. Grades: Purified. CAS No. 940943-37-3. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| KDAMP | HGAPDH is a cationic peptide isolated from Homo sapiens. It has activity against gram-negative bacteria. Synonyms: KDAMP 19-mer; H-Arg-Ala-Ile-Gly-Gly-Gly-Leu-Ser-Ser-Val-Gly-Gly-Gly-Ser-Ser-Thr-Ile-Lys-Tyr-al. Grades: 95.4%. Molecular formula: C75H127N23O25. Mole weight: 1751.0. | |
| KDM4D-IN-1 | A novel histone lysine demethylase 4D (KDM4D) inhibitor (IC50= 0.41±0.03 μM). Synonyms: KDM4D-IN-1; KDM4D IN 1. CAS No. 2098902-68-0. Molecular formula: C11H7N5O. Mole weight: 225.21. | |
| KDM4DL human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| KDM5A-IN-1 | KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1905481-36-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100014. |  |
| KDM5A-IN-1 | KDM5A-IN-1, a pyrrolidine amide compound, is an inhibitor histone demethylases. Synonyms: KDM5A-IN-1; KDM5A IN 1; KDM5AIN1; KDM5A inhibitor-1; KDM5A inhibitor 1; N-[(3R)-1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]cyclopropanecarboxamideKDM5A-IN-1. CAS No. 1905481-36-8. Molecular formula: C15H22N4O2. Mole weight: 290.36. | |
| KDM5C (1-671), GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| KDM5-C70 | KDM5-C70 is an ethyl ester derivative of KDM5-C49 and a potent, cell-permeable and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1596348-32-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 250 mg. Product ID: HY-120400. | |
| KDM5-IN-1 | KDM5-IN-1 is a potent and selective KDM5 inhibitor with modest cell activity (PC9 H3K4Me3 EC50 = 5.2 μM). Synonyms: KDM5-IN-48; KDM5 IN 48; KDM5IN48; KDM5 inhibitor-48; KDM5 inhibitor 48; 5-(1-tert-butylpyrazol-4-yl)-7-oxo-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile. CAS No. 1628210-26-3. Molecular formula: C17H20N6O. Mole weight: 324.38. | |
| KDM5-inhibitor | KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells. Synonyms: KDM5 inhibitor; 7-oxo-5-phenyl-6-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Molecular formula: C16H14N4O. Mole weight: 278.315. | |
| KDN | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Kdo2-Lipid A ((3-Deoxy-D-manno-octulosonic acid)2-Lipid A) | Defined substructure of the Re mutant of lipopolysaccharide (LPS). Strong activator (<10ng/ml) of toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Source:Isolated and purified from E. coli K12 heptose-deficient strain WBB06 (Re mutant) [1] by a modification of the PCP extraction method [2,3], converted to the uniform sodium salt form [4] and dissolved in sterile pyrogen-free double distilled water. Group: Biochemicals. Alternative Names: (3-Deoxy-D-manno-octulosonic acid)2-Lipid A. Grades: Purified. CAS No. 123621-04-5 (free base). Pack Sizes: 1mg. Molecular Formula: C110H198N2Na4O39P2, Molecular Weight: 2326.7. US Biological Life Sciences. | Worldwide |
| Kdo2-Lipid A ammonium | Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 1246298-62-3. Pack Sizes: 1 mg. Product ID: HY-N8277. | |
| Kdo2-Lipid A (KLA) | Kdo2-Lipid A (KLA) is a potent immunostimulatory compound used in biomedical field. It activates immune cells via Toll-like receptor 4 (TLR4), triggering cytokine production and enhancing immune responses. This product aids in the study of immune regulation and the development of vaccines and therapeutics targeting infectious diseases, cancer and inflammation. Synonyms: Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt). Grades: >95%. CAS No. 1246298-62-3. Molecular formula: C110H202N2O39P2.4NH3. Mole weight: 2415.69. | |
| Kdo2-lipid A phosphoethanolamine 7''-transferase | The enzyme has been characterized from the bacterium Escherichia coli. It is activated by Ca2+ ions and is is silenced by the sRNA MgrR. Group: Enzymes. Synonyms: eptB (gene name). Enzyme Commission Number: EC 2.7.8.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3342; Kdo2-lipid A phosphoethanolamine 7''-transferase; EC 2.7.8.42; eptB (gene name). Cat No: EXWM-3342. |  |
| Kdo2-lipid A phosphotransferase | An inner-membrane protein. The activity of the enzyme is regulated by PmrA. In vitro the enzyme can use diacylglycerol 3-diphosphate as the phosphate donor. Group: Enzymes. Synonyms: lipid A undecaprenyl phosphotransferase; LpxT; YeiU. Enzyme Commission Number: EC 2.7.4.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3211; Kdo2-lipid A phosphotransferase; EC 2.7.4.29; lipid A undecaprenyl phosphotransferase; LpxT; YeiU. Cat No: EXWM-3211. | |
| Kdo2-lipid IVA lauroyltransferase | The enzyme, characterized from the bacterium Escherichia coli, is involved in the biosynthesis of the phosphorylated outer membrane glycolipid lipid A. Group: Enzymes. Synonyms: LpxL; htrB (gene name); dodecanoyl-[acyl-carrier protein]:α-Kdo-(2?4)-α-Kdo-(2?6)-lipid IVA O-dodecanoyltransferase; lauroyl-[acyl-carrier protein]:Kdo2-lipid IVA O-lauroyltransferase; (Kdo)2-lipid IVA lauroyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA lauroyltransferase. Enzyme Commission Number: EC 2.3.1.241. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2190; Kdo2-lipid IVA lauroyltransferase; EC 2.3.1.241; LpxL; htrB (gene name); dodecanoyl-[acyl-carrier protein]:α-Kdo-(2?4)-α-Kdo-(2?6)-lipid IVA O-dodecanoyltransferase; lauroyl-[acyl-carrier protein]:Kdo2-lipid IVA O-lauroyltransferase; (Kdo)2-lipid IVA lauroyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA lauroyltransferase. Cat No: EXWM-2190. | |
| Kdo2-lipid IVA palmitoleoyltransferase | The enzyme, characterized from the bacterium Escherichia coli, is induced upon cold shock and is involved in the formation of a cold-adapted variant of the outer membrane glycolipid lipid A. Group: Enzymes. Synonyms: LpxP; palmitoleoyl-acyl carrier protein-dependent acyltransferase; cold-induced palmitoleoyl transferase; palmitoleoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase; (Kdo)2-lipid IVA palmitoleoyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA palmitoleoyltransferase. Enzyme Commission Number: EC 2.3.1.242. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2191; Kdo2-lipid IVA palmitoleoyltransferase; EC 2.3.1.242; LpxP; palmitoleoyl-acyl carrier protein-dependent acyltransferase; cold-induced palmitoleoyl transferase; palmitoleoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase; (Kdo)2-lipid IVA palmitoleoyltransferase; α-Kdo-(2?4)-α-(2?6)-lipid IVA palmitoleoyltransferase. Cat No: EXWM-2191. | |
| KDOAM25 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| KDOAM-25 citrate | KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 citrate increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2448475-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-102047B. | |
| Kdo Azide | Kdo Azide is a click chemistry reagent containing an azide. Kdo Azide is a metabolic labeling reagent[1]. Kdo Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380099-68-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151685. | |
| KD Plus DNA Polymerase | KD Plus DNA Polymerase. Kd plus dna polymerase is a genetically modified high fidelity dna polymerase. this enzyme provides higher amplification capability than traditional pfu dna polymerase and fast amplification speed equal to taq dna polymerase (1 kb/min). due to strong 3-5 exonuclease activity, this enzyme offers 108-fold fidelity as compared to taq dna polymerase. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 100U; 200U. Storage: Store at -20 ?. Cat No: CE-3019. | |
| KDR (789-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| KDR-in-4 | A potent kinase insert domain-containing receptor (KDR/VEGFR2) inhibitor (IC50= 7 nM). Synonyms: 3-[5-[2-[2-methoxyethyl(methyl)amino]ethoxy]-1H-indol-2-yl]-1H-quinolin-2-one. CAS No. 408502-06-7. Molecular formula: C23H25N3O3. Mole weight: 391.46. | |
| KDU691 | KDU691 is a plasmodium PI4K inhibitor (IC50 values of 0.18 μM and 0.061 μM against hypnozoite forms and liver schizontsm, respectively) that inhibits dihydroartemisinin-pretreated plasmodium falciparum ring-stage parasites. Synonyms: KDU691; KDU-691; KDU 691; HY-12912; HY 12912; HY12912; N-(4-chlorophenyl)-N-methyl-3-[4-(methylcarbamoyl)phenyl]imidazo[1,2-a]pyrazine-6-carboxamide. Grades: 98%. CAS No. 1513879-19-0. Molecular formula: C22H18ClN5O2. Mole weight: 419.86. | |
| KDU691 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| KDU-731 | KDU-731 is a selective inhibitor of Cryptosporidium lipid kinase PI(4)K over human PI(4)K. It exhibits potential cardiotoxicity, mutagenicity, clastogenicity or phototoxicity. KDU-731 is a new treatment for pediatric diarrhea caused by the parasite Cryptosporidium. Uses: Pediatric diarrhea caused by the parasite cryptosporidium. Synonyms: KDU 731; KDU731. CAS No. 1610610-48-4. Molecular formula: C22H16N6O2. Mole weight: 396.40. | |
| KEA1-97 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Kebuzone | Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketazone; Ketophenylbutazone. CAS No. 853-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111284. | |
| Kebuzone | Kebuzone. Group: Biochemicals. Alternative Names: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedion. Grades: Highly Purified. CAS No. 853-34-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C19H18N2O3. US Biological Life Sciences. | Worldwide |
| Kebuzone | Kebuzone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Kebuzone;Ketophenyl butazone. Product Category: Heterocyclic Organic Compound. CAS No. 853-34-9. Molecular formula: C19H18N2O3. Mole weight: 322.36. Product ID: ACM853349. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Kebuzone | Kebuzone is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory activities. Kebuzone is a cyclooxygenase inhibitor. It can block the synthesis of prostaglandins by inhibiting cyclooxygenase. Uses: Non-steroidal anti-inflammatory drug. Synonyms: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-4-(2-acetylethyl) pyrazolidine-3,5-dione; Chebutan; Chepirol; Chetazol; Chetazolidin; Chetil; Chetopir; Copirene; Ejor; Gammachetone; KPB; Ketanol; Ketason; Ketazon; Ketazone; Ketophenylbutazone; Pecnon; Phloguron; Recheton; Reuchetal; γ-Ketazone; γ-Ketophenylbutazone; γ-Oxophenylbutazone. Grades: 98%. CAS No. 853-34-9. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
| Kecaoan | Kecaoan. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monsanto 31675, CP 31675, 2-tert-Butyl-6-methylchloroacetanilide, CID19616, BRN 2730032, o-Acetotoluidide, 6-tert-butyl-2-chloro-, LS-13754, 2-Chloro-N-(2-methyl-6-tert-butylphenyl)acetamide, Acetamide, 2-chloro-N-(2-(1,1-dimethylethyl)-6-methylphenyl)-, Acetamide, 2-chloro-N-(2-(1,1-dimethylethyl)-6-methylphenyl)- (9CI), 3785-20-4. Product Category: Heterocyclic Organic Compound. CAS No. 3785-20-4. Molecular formula: C13H18CLNO2. Mole weight: 239.741120 [g/mol]. Purity: 0.96. IUPACName: N-[2-tert-butyl-6-(chloromethyl)phenyl]acetamide. Canonical SMILES: CC1=C(C(=CC=C1)C(C)(C)C)NC(=O)CCl. Product ID: ACM3785204. Alfa Chemistry ISO 9001:2015 Certified. Categories: N-(2-tert-butyl-6-methylphenyl)-2-chloroacetamide. | |
| KEL-FIM-FAME mixture-5 | KEL-FIM-FAME mixture-5. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Synthetic or plant. KEL-FIM-FAME mixture-5; GC; KEL-FIM-FAME-5 Mixture (Methyl ester mixture); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-107. | |
| Keliximab | Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a K i value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SB-210396; IDEC CE9.1. CAS No. 174722-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99680. | |
| Kellers Etchant | Excellent for aluminum and titanium alloys. Group: Etchants. |  |
| Kelp Extract | Kelp Extract. Applications: It can be applied in health food field, food additives industry, which can be added into the dairy, beverage, health care products, pastries, cold drinks, bread, milk and so on.it can be applied in cosmetic field, which is a kind of water-soluble polymer natural extracts with sntiphlogistic sterilization effect. so fucoidan can be used as a new type of high moisturizing instead of glycerin;it can be applied in pharmaceutical field, which is the raw material of new traditionmedicine added in kidney products. Group: Others. Purity: 10:1,20:1,Fucoxanthin 5%-50%(UV). Source: Kelps are large seaweeds (algae) belonging to the brown algae (Phaeophyceae) in the order Laminariales. There are about 30 different genera. Kelp Extract. Cat No: EXTC-190. | |
| Kelp Leaf Powder & P.E 4:1 TLC (Laminaria Digitate) | Kelp Leaf Powder & P.E 4:1 TLC (Laminaria Digitate). Categories: l-theanine; 3081-61-6. |  CA, FL & NJ |
| Kemp's triacid | Kemp's triacid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,5-Trimethylcyclohexane-1β,3β,5β-tricarboxylic acid. Product Category: Carboxylic Acid Monomers. CAS No. 79410-20-1. Molecular formula: C12H18O6. Mole weight: 258.27 g/mol. Purity: 0.95. Product ID: ACM-MO-79410201. Alfa Chemistry ISO 9001:2015 Certified. | |
| Kemps triacid | Kemps triacid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CIS,CIS-1,3,5-TRIMETHYLCYCLOHEXANE-1,3,5-TRICARBOXYLIC ACID;KEMPS TRIACID;cis,cis-1,3,5-trime.cyclohexane-1,3,5-tricarboxylic acid;1,3,5-Trimethyl-1,3,5-cyclohexanetricarboxylicacid(Kempstriacid);Aluminum oxide, fused, #200+325 mesh, 99+% metals basis;cis. Product Category: Polymer/Macromolecule. CAS No. 79410-20-1. Molecular formula: C12H18O6. Mole weight: 258.27. Product ID: ACM79410201. Alfa Chemistry ISO 9001:2015 Certified. | |
| Kemptide | Kemptide, a synthetic heptapeptide, acts as a specific substrate for cAMP-dependent protein kinase (PKA) and is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. Synonyms: H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH; L-leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucyl-glycine; (5S,8S,11S,14S,17S,20S)-20-amino-14,17-bis(3-guanidinopropyl)-8-(hydroxymethyl)-5-isobutyl-11,22-dimethyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazatricosan-1-oic acid. Grades: ≥97% by HPLC. CAS No. 65189-71-1. Molecular formula: C32H61N13O9. Mole weight: 771.91. | |
| Kemptide | Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase ( PKA ). Uses: Scientific research. Group: Peptides. CAS No. 65189-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0248. | |
| Kemptide Phospho-Ser5 | Kemptide (Phospho-Ser5), a phosphate acceptor peptide, serves as a specific substrate for cAMP-dependent protein kinase (PKA). Synonyms: Leu-Arg-Arg-Ala-pSer-Leu-Gly; H-Leu-Arg-Arg-Ala-Ser(PO3H2)-Leu-Gly-OH; L-leucyl-L-arginyl-L-arginyl-L-alanyl-O-phosphono-L-seryl-L-leucyl-glycine; phosphokemptide; Kinase Domain of Pyruvate Kinase porcine. Grades: ≥95%. Molecular formula: C32H62N13O12P. Mole weight: 851.89. | |
| Kendomycin | Kendomycin is an endothelin receptor antagonist and proteasome inhibitor. It induces apoptosis in lymphoma. It is a potent antibacterial agent against gram-positive and gram-negative bacteria, including MRSA strains. Synonyms: TAN 2162. Grades: >95% by HPLC. CAS No. 183202-73-5. Molecular formula: C29H42O6. Mole weight: 486.64. | |
| Kendomycin (Antibiotic TAN 2162) | Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and negative bacteria including MRSA strains, also displaying antitumor activity. Kendomycin has been reported to be a potent endothelin receptor agonist and has been demonstrated to possess antiosteoporotic activity. Group: Biochemicals. Alternative Names: Antibiotic TAN 2162. Grades: Highly Purified. CAS No. 183202-73-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Kendomycin from Streptomyces violaceoruber | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Kendomycin ((-)-TAN 2162) | Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial. Cytotoxic. Mediates its cytotoxic effects, at least in part, through proteasome inhibition. Group: Biochemicals. Grades: Highly Purified. CAS No. 183202-73-5. Pack Sizes: 100ug, 500ug. US Biological Life Sciences. | Worldwide |
| Kenojeinin I | Kenojeinin I is an antibacterial peptide isolated from Raja kenojei. Synonyms: Gly-Lys-Gln-Tyr-Phe-Pro-Lys-Val-Gly-Gly-Arg-Leu-Ser-Gly-Lys-Ala-Pro-Leu-Ala-Ala-Lys-Thr-His-Arg-Arg-Leu-Lys-Pro-NH2. Grades: 96.5%. Molecular formula: C139H234N46O32. Mole weight: 3061.5. | |
| Kenpaullone | Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively). Uses: Reprogramming. Synonyms: NSC664704; NSC-664704; NSC 664704; 9-Bromopaullone; 1-azakenpaullone; Kenpaullone. Grades: 98%. CAS No. 142273-20-9. Molecular formula: C16H11BrN2O. Mole weight: 327.18. | |
| Kenpaullone | Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β , with IC 50 s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC 50 s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4 , reduces self-renewal of breast cancer stem cells and cell motility in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Bromopaullone; NSC-664704. CAS No. 142273-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12302. | |
| Kenpaullone | Kenpaullone. Group: Biochemicals. Grades: Purified. CAS No. 142273-20-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kenpaullone | ?98%. Group: Fluorescence/luminescence spectroscopy. | |
| Kenpaullone (8-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one) | The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3ß inhibitor (IC50=23nM). Group: Biochemicals. Alternative Names: 8-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kenpaullone - CAS 142273-20-9 | A potent, cell-permeable, and reversible inhibitor of glycogen synthase kinase-3? (IC?? = 230 nM), Lck (IC?? = 470 nM), and cyclin-dependent kinases (Cdks). Group: Fluorescence/luminescence spectroscopy. | |
| Kephalis | Kephalis. CAS No. 36306-87-3. VIGON Item # 500908. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| KER047 | ALK2-IN-4 is a potent ALK2 inhibitor extracted from patent WO2020086963A1, compound Formula I free base [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALK2-IN-4. CAS No. 2248154-85-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136773. | |
| KER047 succinate | ALK2-IN-4 succinate is a potent ALK2 inhibitor extracted from patent WO2020086963A1, compound Formula I free base [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALK2-IN-4 succinate. CAS No. 2416307-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136773A. | |
| Keracyanin chloride | analytical standard. Group: Chemical class. | |
| Keracyanin chloride | Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin, has antioxidant activity. Keracyanin chloride inhibits malonaldehyde formation in oxidized calf thymus DNA [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyanidin 3-rutinoside chloride; Cyanidin 3-O-rutinoside chloride; Sambucin chloride. CAS No. 18719-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105935. | |
| Keracyanin chloride | Keracyanin chloride is an anthocyanin found in many plants. It exhibits high antioxidant activity and protects erythrocytes from apoptosis. Synonyms: Cyanidin 3-rutinoside; Meralop; Sambucin; Antirrhinin; Prunicyanin. Grades: ≥98%. CAS No. 18719-76-1. Molecular formula: C27H31O15·Cl. Mole weight: 631. | |
| Keratanase II from Bacillus circulans, Recombinant | Keratansae II hydrolyzes 1, 3-beta-glucosaminidic linkages to galactose in keratan sulfate. On cleavage, the enzyme requires the sulfate at 6-0 position of the participating glucosamine, but acts independently of the sulfate at 6-0 position of the galactose linked to the glucosamine. Applications: Used in the screening and diagnosis of morquio a syndrome (mps iva). validation of an lc-ms/ms assay for detecting relevant disaccharides from keratan sulfate as a biomarker for morquio a syndrome. Group: Enzymes. Purity: >90%. Endo-β-galactosidase. Storage: Reconstituted protein can be stored at 4°C or in small aliquots at -20°C or below. Avoid repeated freeze-thaw cycles. Form: Powder. Source: E. coli. Species: Bacillus circulans. Endo-β-galactosidase; endo-β-galactosidase; keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase; Keratanase II. Cat No: NATE-1618. | |
| keratan-sulfate endo-1,4-β-galactosidase | Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to 1,3-N-acetyl-α-D-glucosaminyl residues. Also acts on some non-sulfated oligosaccharides, but only acts on blood group substances when the 1,2-linked fucosyl residues have been removed (cf. EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase). Group: Enzymes. Synonyms: endo-β-galactosidase (ambiguous); keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.103. CAS No. 55072-01-0. Endo-β-galactosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3786; keratan-sulfate endo-1,4-β-galactosidase; EC 3.2.1.103; 55072-01-0; endo-β-galactosidase (ambiguous); keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase. Cat No: EXWM-3786. | |
| Keratan sulfate Endo-N-acetylglucosaminidase 111A from Bacillus circulans | BcKsh111A (GH111), E.C. number 3.2.1.-, is an endo-β -N-acetylglucosaminidase from Bacillus circulans. Recombinant BcKsh111A (GH111), purified from Escherichia coli, is a single domain family 111 Glycoside Hydrolase (GH111). Group: Enzymes. Synonyms: endo-β -N-acetylglucosaminidase; single domain family 111 Glycoside Hydrolase; Keratan sulfate Endo-N-acetylglucosaminidase 111A; Keratan sulfate Endo-N-acetylglucosaminidase; GH111. Enzyme Commission Number: EC 3.2.1.-. Purity: >90% as judged by SDS-PAGE. α-L-Arabinofuranosidase. Mole weight: 69,07 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacillus circulans. endo-β -N-acetylglucosaminidase; single domain family 111 Glycoside Hydrolase; Keratan sulfate Endo-N-acetylglucosaminidase 111A; Keratan sulfate Endo-N-acetylglucosaminidase; GH111. Cat No: NATE-1940. | |
| keratan sulfotransferase | Sulfation takes place at the 6-position of galactosyl and N-acetylglucosaminyl residues in keratan, a proteoglycan. Not identical with EC 2.8.2.5 (chondroitin 4-sulfotransferase), EC 2.8.2.6 (choline sulfotransferase) or EC 2.8.2.17 (chondroitin 6-sulfotransferase). Group: Enzymes. Synonyms: 3'-phosphoadenylyl keratan sulfotransferase; keratan sulfate sulfotransferase; 3'-phosphoadenylylsulfate:keratan sulfotransferase. Enzyme Commission Number: EC 2.8.2.21. CAS No. 62168-79-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3380; keratan sulfotransferase; EC 2.8.2.21; 62168-79-0; 3'-phosphoadenylyl keratan sulfotransferase; keratan sulfate sulfotransferase; 3'-phosphoadenylylsulfate:keratan sulfotransferase. Cat No: EXWM-3380. | |
| Keratin-8 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Keratinase | Keratinase (KerA) is a protease that are able to degrade keratins into amino acids [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KerA. CAS No. 37341-53-0. Pack Sizes: 500 U. Product ID: HY-E70193. | |
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