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| Product | Description | |
|---|---|---|
| KGL360 6 Anderson Product | KGL360 6 Anderson Chemicals Description | Anderson Chemicals |
| KGL360 6 Eliana Product | KGL360 6 Eliana Chemicals Description | Eliana Chemicals |
| KGL360 6 Makayla Product | KGL360 6 Makayla Chemicals Description | Eliana Chemicals |
| KGL360 6 Rebekah Product | KGL360 6 Rebekah Chemicals Description | Rebekah Chemicals |
| KGL360 6 Roberts Product | KGL360 6 Roberts Chemicals Description | Roberts Chemicals |
| KH-3 | KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC 50 value of 0.35 μM. KH-3 has anti-proliferative activity. KH-3 suppresses breast cancer cell invasion as well as delays the initiation of lung colonies by disrupting HuR-FOXQ1 mRNA interaction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215115-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134601. |  |
| KH7 | KH7 is a soluble adenylyl cyclase (sAC) -specific inhibitor, with IC 50 s of 3-10 μM toward both recombinant purified human sAC t protein and heterologously expressed sACt in cellular assays [1]. KH7 is also a cAMP inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 330676-02-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103194. | |
| KH7 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| KH 7 | KH 7 is a novel and selective inhibitor of soluble adenylyl cyclase (Sac) with IC50 value of 3 - 10 μM in vivo, which is an essential component of cAMP-signaling and is ubiquitously expressed. It blocks cAMP synthesis and shows an antiapoptotic effect at concentrations of 1 - 100 μM. Synonyms: KH7; KH 7; KH-7; (E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide; 2-(1H-Benzoimidazol-2-ylsulfanyl)-propionic acid (5-bromo-2-hydroxy-benzylidene)-hydrazide; (±)-2-(1H-benzimidazol-2-ylthio)propanoic acid 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide. Grades: ≥99% by HPLC. CAS No. 330676-02-3. Molecular formula: C17H15BrN4O2S. Mole weight: 419.30. |  |
| KH 7 | KH 7. Group: Biochemicals. Grades: Purified. CAS No. 330676-02-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Khasianine | Khasianine. Group: Biochemicals. Alternative Names: β2-Solamargine. Grades: Plant Grade. CAS No. 32449-98-2. Pack Sizes: 10mg. Molecular Formula: C39H63NO11, Molecular Weight: 721.918. US Biological Life Sciences. | Worldwide |
| KH-CB19 | KH-CB19, a CLK1/CLK4 inhibitor, has been found to probably restrain the phosphorylation of serine- and arginine-rich (SR) proteins. IC50: 20 nM for CLK1. Uses: Kh-cb19 is a clk1/clk4 inhibitor that has been found to probably restrain the phosphorylation of serine- and arginine-rich (sr) proteins. Synonyms: KH-CB19; KH CB19; KHCB19. Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate; 2wu7; GTPL8055; 3761AH. Grades: 98%. CAS No. 1354037-26-5. Molecular formula: C15H13Cl2N3O2. Mole weight: 338.19. | |
| Khellin | analytical standard. Group: Herbal medicinal products standards. | |
| Khellin | 5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C14H12O5. CAS No. 82-02-0. Prepack ID 13358619-5g. Molecular Weight 260.24. See USA prepack pricing. |  |
| Khellin | Khellin. Group: Biochemicals. Alternative Names: 4,9-Dimethoxy-7-Methyl-5H-Furo[3,2-G]-[1]Benzopyran-5-One. Grades: Highly Purified. CAS No. 82-02-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C14H12O5. US Biological Life Sciences. | Worldwide |
| Khellin | Khellin is a furochromone that can be isolated from Ammi visnuga L. Khellin is an EGFR inhibitor with an IC 50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 82-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1394. | |
| KHK-IN-1 | KHK-IN-1, a pyrimidinopyrimidine derivative, is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in the ATP-binding region at some extent. Uses: Khk-in-1 is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on asp-27b in the atp-binding region at some extent. Synonyms: KHK-IN-8; KHK IN 8; KHKIN8; KHK inhibitor 8; KHK-inhibitor-8; Ketohexokinase Inhibitor 8; ketohexokinase inhibitor. Grades: 98%. CAS No. 1303469-70-6. Molecular formula: C21H26N8S. Mole weight: 422.55. | |
| KHK-IN-1 hydrochloride | The hydrochloride salt form of KHK-IN-1 which is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in the ATP-binding region at some extent. Uses: The hydrochloride salt form of khk-in-1 which is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on asp-27b in the atp-binding region at some extent. Synonyms: MDK-0485; MDK0485; MDK 0485; ketohexokinase inhibitor. Grades: 98%. CAS No. 1303470-48-5. Molecular formula: C21H27ClN8S. Mole weight: 459.01. | |
| KHR70S hydrogenated rosin resin | | |
| KHS101 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| KHS101 | KHS101 is a selective inducer of neuronal differentiation. Synonyms: N4-Isobutyl-N2-((2-Phenylthiazol-4-Yl)Methyl)Pyrimidine-2,4-Diamine; KHS-101; N4-(2-Methylpropyl)-N2-[(2-Phenyl-1,3-Thiazol-4-Yl)Methyl]Pyrimidine-2,4-Diamine. Grades: 98%. CAS No. 1262770-73-9. Molecular formula: C18H21N5S. Mole weight: 339.5. | |
| KHS 101 hydrochloride | KHS 101 hydrochloride is the hydrochloride salt of KHS 101, which is an inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo and induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3. It suppresses astrocyte formation. It is a useful intermediate. Synonyms: KHS 101 hydrochloride; KHS-101 hydrochloride; KHS101 hydrochloride; N4-(2-Methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediamine hydrochloride; N4-isobutyl-N2-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine hydrochloride. Grades: ≥98% by HPLC. CAS No. 1784282-12-7. Molecular formula: C18H22ClN5S. Mole weight: 375.92. | |
| KHS 101 hydrochloride | KHS 101 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KHS101 hydrochloride | KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3). Uses: Scientific research. Group: Signaling pathways. CAS No. 1784282-12-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10996A. | |
| KHS1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Khusenol | Khusenol, is a component of Vetiver essential oil which is a highly esteemed basic ingredient of modern perfumery, hvaing a woody, earthy scent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16223-63-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H24O, Molecular Weight: 220.35. US Biological Life Sciences. | Worldwide |
| Ki11502 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ki16198 | Ki16198, the methyl ester of Ki16425, is a potent and orally active LPA receptor antagonist with Kis of 0.34 and 0.93 μM against inositol phosphate production induced by LPA1 and LPA3, respectively. It is effective for pancreatic cancer tumorigenesis and metastasis in vivo. Synonyms: 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonylamino)-3-methyl-5-isoxazolyl)benzylsulfanyl)propanoic acid methyl ester; Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester; KI-16198; KI 16198; Methyl 3-((4-(4-(((1-(2-chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)benzyl)thio)propanoate. Grades: >98%. CAS No. 355025-13-7. Molecular formula: C24H25ClN2O5S. Mole weight: 488.98. | |
| Ki16425 | Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6. Synonyms: Ki16425; Ki-16425; Ki 16425. Grades: >98%. CAS No. 355025-24-0. Molecular formula: C23H23ClN2O5S. Mole weight: 474.96. | |
| Ki16425 | Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with K i s of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA -induced activation of p42/p44 MAPK [1] [2]. Ki16425 can also inhibit LPA -induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 0719. CAS No. 355025-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13285. | |
| Ki 16425 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ki 16425 | Ki 16425. Group: Biochemicals. Grades: Purified. CAS No. 355025-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ki20227 | Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Synonyms: Ki20227; Ki 20227; Ki-20227. Grades: >98%. CAS No. 623142-96-1. Molecular formula: C24H24N4O5S. Mole weight: 480.54. | |
| Ki 20227 | Ki 20227. Group: Biochemicals. Grades: Purified. CAS No. 623142-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ki23057 | Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism between Ki23057 and chemotherapeutic agents in drug-resistant cell lines. Synonyms: Ki-23057; Ki 23057; 2-((2-((4-(4-((4-(1,1-Dimethylethyl)phenyl)amino)phenoxy)-6-methoxy-7-quinolinyl)oxy)ethyl)amino)ethanol. Grades: 98%. CAS No. 516523-31-2. Molecular formula: C30H35N3O4. Mole weight: 501.63. | |
| KI-328 | KI-328 is a novel KIT inhibitor. KI-328 shows selective potency against KIT kinase for the in vitro kinase assay, and inhibits the growth of wild-type (Wt)- and mutant-KIT-expressing cells, while it has little potency against D816V-KIT. Synonyms: KI 328; KI328. Grades: 98%. CAS No. 930089-25-1. Molecular formula: C25H25N7O3. Mole weight: 471.51. | |
| KI-7 | KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC 50 =445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC 50 s of 2390 nM and 2550 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1489263-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131032. | |
| Ki8751 | Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFRα and FGFR-2 (IC50 values range from 40 to 170 nM). Synonyms: Ki8751; Ki-8751; Ki 8751. Grades: 0.98. CAS No. 228559-41-9. Molecular formula: C24H18F3N3O4. Mole weight: 469.41. | |
| Ki8751 | Ki8751 is a potent VEGFR2 inhibitor with an IC 50 of 0.9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 228559-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12038. | |
| Ki 8751 | Ki 8751. Group: Biochemicals. Grades: Purified. CAS No. 228559-41-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Kibdelin A | Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38. | |
| Kibdelin B | Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41. | |
| Kibdelin C1 | Kibdelin C1 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C1 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103549-47-9. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin C2 | Kibdelin C2 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C2 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-85-1. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin D | Kibdelin D is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin D is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-86-2. Molecular formula: C81H82Cl4N8O29. Mole weight: 1773.36. | |
| Kibdelone A | It is a potent antitumour metabolite isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. It's cytotoxic. Synonyms: (10S,12S,13R)-4-Chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-77-4. Molecular formula: C29H24ClNO10. Mole weight: 581.96. | |
| Kibdelone B | It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10R,12R,13S)-rel-(+)-4-Chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-78-5. Molecular formula: C29H26ClNO10. Mole weight: 583.97. | |
| Kibdelone C | It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99. | |
| Kidney, Rabbit | Kidney, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences. | Worldwide |
| Kidney-targeted In Vivo Kit | Kidney-targeted in vivo transfection kit. Functionally tested in mice tissue-targeted delivery of siRNA and pDNA via IV,IP,IT administrations. Kit includes: In vivo delivery reagent. Transfection Enhancer reagent. Protocol for mice and rats. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 5071. |  Nevada, Texas, USA |
| kievitone hydratase | The enzyme from Fusarium sp. hydrates the methylbutenyl sidechain of the isoflavonoid phytoalexins, thus reducing their toxicity. Group: Enzymes. Synonyms: KHase; kievitone-hydrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.95. CAS No. 70431-10-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5079; kievitone hydratase; EC 4.2.1.95; 70431-10-6; KHase; kievitone-hydrate hydro-lyase. Cat No: EXWM-5079. |  |
| Kif15-IN-1 | Kif15-IN-1 is a potent Kif15 kinesin inhibitor, which inhibits cellular proliferation in tumor cell lines. Synonyms: KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1. Grades: >98%. CAS No. 672926-32-8. Molecular formula: C20H22N4O5S. Mole weight: 430.48. | |
| Kif15-IN-2 | Kif15-IN-2 is a potent Kif15 kinesin inhibitor, which inhibits cellular proliferation in tumor cell lines. Synonyms: KIF15-IN-2; KIF15IN-2; KIF15-IN2; KIF15IN2; KIF15 IN 2. Grades: >98%. CAS No. 672926-33-9. Molecular formula: C20H20N6O4S. Mole weight: 440.48. | |
| Kifunensine | Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense. It is a potent inhibitor of the mannosidase I enzyme. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Kifunensine | Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: FR-900494. CAS No. 109944-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19332. | |
| Kifunensine | mannosidase inhibitor. Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. | |
| Kifunensine diacetonide | Kifunensine diacetonide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kifunensine diacetonide | Kifunensine diacetonide, an indispensable biomedicine tool revered for its potency, takes center stage in the realm of therapeutic interventions for glycoprotein-based diseases. Its remarkable prowess lies in its profound inhibition of α-mannosidase I, thereby triggering the unprecedented accumulation of high-mannose glycoproteins. This profound offering stands as a gateway to unraveling novel revelations surrounding afflictions including cancer, viral infections, and genetic disorders intimately entwined with the intricate world of protein glycosylation. Synonyms: (3aS,3bR,7aR,11aS,11bR)-Hexahydro-2,2,5,5-tetramethyl-7H-[1,3]dioxino[4,5-e]-1,3-dioxolo[4,5-c]imidazo[1,2-a]pyridine-9,10-dione. CAS No. 134234-43-8. Molecular formula: C14H20N2O6. Mole weight: 312.32. | |
| Kigamicin A | Kigamicin A is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C34H35NO13. Mole weight: 665.64. | |
| Kigamicin B | Kigamicin B is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C40H45NO15. Mole weight: 779.78. | |
| Kigamicin C | Selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions; active in vivo against a human pancreatic cancer xenograft model; also inhibits the growth of gram positive bacteria including MRSA, but is not active against gram negative bacteria. Synonyms: (1S, 3R, 4S, 8aR, 11aR)-3-[[(2S, 5S, 6R)-5-[(2, 6-dideoxy-3-O-methyl-b-D-arabinohexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1, 2, 3, 4, 8a, 9, 11, 11a, 13, 14-decahydro-1, 4, 17, 18-tetrahydroxy-11a-methyl-oxazolo[3, 2-b]xantheno[4', 3', 2':4, 5][1, 3]benzodioxino[7, 6-g]isoquinoline-16, 19-dione. Grades: >98% by HPLC. CAS No. 680571-51-1. Molecular formula: C41H47NO16. Mole weight: 809.81. | |
| Kigamicin C | Kigamicin C was discovered by an anti-austerity strategy targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blocking of the activation of PKB/Akt caused by the withdrawal of nutrients. Active in vivo against a human pancreatic cancer xenograft model. Also inhibits the growth of Gram-positive bacteria including Staphylococcus aureus MRSA, but not active against Gram-negative bacteria. Group: Biochemicals. Grades: Highly Purified. CAS No. 680571-51-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Kigamicin D | Kigamicin D is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. It also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL. Synonyms: 1,2,3a,4,6,7,10,11,12,13-Decahydro-11-[[5-[[5-[(tetrahydro-5-hydroxy-4-methoxy-6-methyl-2H-pyran-2-yl)oxy]tetrahydro-4-methoxy-6-methyl-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-10,13,15,16-tetrahydroxy-3a-methyl-7,8-(methylenedioxy)-17a-aza-3,9-dioxa-17aH-cyclopenta[b]hexaphene-14,17-dione. Molecular formula: C48H59NO19. Mole weight: 953.98. | |
| Kihadanin B | Kihadanin B is a citrus limonoid that can be purified from the peels of immature Citrus unshiu. Kihadanin B suppresses adipogenesis through repression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 73793-68-7. Molecular formula: C26H30O9. Mole weight: 486.5. Purity: 0.98. Canonical SMILES: CC1(C2CC(=O)C3(C(C2(C=CC(=O)O1)C)CCC4(C35C(O5)C(=O)OC4C6=CC(OC6=O)O)C)C)C. Product ID: ACM73793687. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Kijanimicin | Kijanimicin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: kijanimicin. Product Category: Heterocyclic Organic Compound. CAS No. 78798-08-0. Molecular formula: C67H100NO24. Mole weight: 1317.5099;g/mol. Purity: 0.96. IUPACName: From Actinomadura Kijaniata. Canonical SMILES: CC1CC(C(C2C1C3(C(C=C2)C(=CCC(C(=CC4C=C(C(CC45C(=O)C(=C3O)C(=O)O5)C)CO)C)OC6CC(C(C(O6)C)NC(=O)OC)(C)[N+](=O)[O-])C)C)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC9CC(C(C(O9)C)OC)O)OC1CC(C(C(O1)C)O)O)C. Density: 1.35g/cm³. Product ID: ACM78798080. Alfa Chemistry ISO 9001:2015 Certified. | |
| Kijanimicin | A tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin; contains an unusual nitroaminoglycoside; a potent antibacterial, antimalarial and antitumour active; inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). Synonyms: NSC 329515; Sch 25663. Grades: >99% by HPLC. CAS No. 78798-08-0. Molecular formula: C67H100N2O24. Mole weight: 1317.51. | |
| Kijanimicin (Antibiotic Sch 25663) | Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor activity. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. While tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Alternative Names: Antibiotic Sch 25663. Grades: Highly Purified. CAS No. 78798-08-0. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Synonyms: KIN-1148; KIN 1148; KIN1148; N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide. Grades: ≥98% (HPLC). CAS No. 1428729-56-9. Molecular formula: C19H11N3OS2. Mole weight: 361.44. | |
| KIN1400 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| KIN1400 | KIN1400 is an IRF3 activator with antiviral activity. It induces IRF3-dependent innate immune gene expression such as RIG-1, MDA5, IFIT1, IFIT2, IFITM1, OAS3, and Mx1 in THP-1 cells stimulated with phorbol 12-myristate 13-acetate (PMA). It also inhibits replication of HCV, West Nile virus, and Paramyxoviridae (RCV, NV). Synonyms: 7- ( (benzo[d]thiazol-2-ylamino) (4- (difluoromethoxy) phenyl) methyl) quinolin-8-ol. Grades: ≥98%. CAS No. 446826-86-4. Molecular formula: C24H17F2N3O2S. Mole weight: 449.5. | |
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