A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
KG-5 is an orally available PDGFRß and B-Raf allosteric inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KG-5; KG 5; KG5. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 877874-85-6. Molecular formula: C20H16F3N7OS. Mole weight: 459.45. Purity: >98%. IUPACName: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine. Canonical SMILES: NC1=NC(SC)=NC(OC2=CC=C(C3=NNC(NC4=CC=CC(C(F)(F)F)=C4)=N3)C=C2)=C1. Product ID: ACM877874856. Alfa Chemistry ISO 9001:2015 Certified. Categories: KG 51.
KGA2727
KGA2727 is a selective and potent SGLT1 inhibitor for the treatment of diabete. Its inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and hSGLT2 respectively. It inhibited the absorption of glucose but not that of fructose. Uses: Kga2727 is used for the treatment of diabete. Synonyms: KGA-2727; KGA 2727; 3- (3-{4-[3- (beta-D-glucopyranosyloxy) -5-isopropyl-1Hpyrazol-4-ylmethyl]-3-methylphenoxy}propylamino) propionamide. Grades: 98%. CAS No. 666842-36-0. Molecular formula: C26H40N4O8. Mole weight: 536.63.
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC 50 value of 0.35 μM. KH-3 has anti-proliferative activity. KH-3 suppresses breast cancer cell invasion as well as delays the initiation of lung colonies by disrupting HuR-FOXQ1 mRNA interaction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215115-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134601.
KH7
KH7 is a soluble adenylyl cyclase (sAC) -specific inhibitor, with IC 50 s of 3-10 μM toward both recombinant purified human sAC t protein and heterologously expressed sACt in cellular assays [1]. KH7 is also a cAMP inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 330676-02-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103194.
KH 7
KH 7. Group: Biochemicals. Grades: Purified. CAS No. 330676-02-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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KH 7
KH 7 is a novel and selective inhibitor of soluble adenylyl cyclase (Sac) with IC50 value of 3 - 10 μM in vivo, which is an essential component of cAMP-signaling and is ubiquitously expressed. It blocks cAMP synthesis and shows an antiapoptotic effect at concentrations of 1 - 100 μM. Synonyms: KH7; KH 7; KH-7; (E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide; 2-(1H-Benzoimidazol-2-ylsulfanyl)-propionic acid (5-bromo-2-hydroxy-benzylidene)-hydrazide; (±)-2-(1H-benzimidazol-2-ylthio)propanoic acid 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide. Grades: ≥99% by HPLC. CAS No. 330676-02-3. Molecular formula: C17H15BrN4O2S. Mole weight: 419.30.
Khasianine
Khasianine. Group: Biochemicals. Alternative Names: β2-Solamargine. Grades: Plant Grade. CAS No. 32449-98-2. Pack Sizes: 10mg. Molecular Formula: C39H63NO11, Molecular Weight: 721.918. US Biological Life Sciences.
Worldwide
KH-CB19
KH-CB19, a CLK1/CLK4 inhibitor, has been found to probably restrain the phosphorylation of serine- and arginine-rich (SR) proteins. IC50: 20 nM for CLK1. Uses: Kh-cb19 is a clk1/clk4 inhibitor that has been found to probably restrain the phosphorylation of serine- and arginine-rich (sr) proteins. Synonyms: KH-CB19; KH CB19; KHCB19. Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate; 2wu7; GTPL8055; 3761AH. Grades: 98%. CAS No. 1354037-26-5. Molecular formula: C15H13Cl2N3O2. Mole weight: 338.19.
Khellin
Khellin is a furochromone that can be isolated from Ammi visnuga L. Khellin is an EGFR inhibitor with an IC 50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 82-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1394.
Khellin
5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C14H12O5. CAS No. 82-02-0. Prepack ID 13358619-5g. Molecular Weight 260.24. See USA prepack pricing.
Khellin
Khellin. Group: Biochemicals. Alternative Names: 4,9-Dimethoxy-7-Methyl-5H-Furo[3,2-G]-[1]Benzopyran-5-One. Grades: Highly Purified. CAS No. 82-02-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C14H12O5. US Biological Life Sciences.
Worldwide
KHK-IN-1
KHK-IN-1, a pyrimidinopyrimidine derivative, is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in the ATP-binding region at some extent. Uses: Khk-in-1 is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on asp-27b in the atp-binding region at some extent. Synonyms: KHK-IN-8; KHK IN 8; KHKIN8; KHK inhibitor 8; KHK-inhibitor-8; Ketohexokinase Inhibitor 8; ketohexokinase inhibitor. Grades: 98%. CAS No. 1303469-70-6. Molecular formula: C21H26N8S. Mole weight: 422.55.
KHK-IN-1 hydrochloride
The hydrochloride salt form of KHK-IN-1 which is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in the ATP-binding region at some extent. Uses: The hydrochloride salt form of khk-in-1 which is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on asp-27b in the atp-binding region at some extent. Synonyms: MDK-0485; MDK0485; MDK 0485; ketohexokinase inhibitor. Grades: 98%. CAS No. 1303470-48-5. Molecular formula: C21H27ClN8S. Mole weight: 459.01.
KHR70S hydrogenated rosin resin
KHS101
KHS101 is a selective inducer of neuronal differentiation. Synonyms: N4-Isobutyl-N2-((2-Phenylthiazol-4-Yl)Methyl)Pyrimidine-2,4-Diamine; KHS-101; N4-(2-Methylpropyl)-N2-[(2-Phenyl-1,3-Thiazol-4-Yl)Methyl]Pyrimidine-2,4-Diamine. Grades: 98%. CAS No. 1262770-73-9. Molecular formula: C18H21N5S. Mole weight: 339.5.
KHS 101 hydrochloride
KHS 101 hydrochloride is the hydrochloride salt of KHS 101, which is an inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo and induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3. It suppresses astrocyte formation. It is a useful intermediate. Synonyms: KHS 101 hydrochloride; KHS-101 hydrochloride; KHS101 hydrochloride; N4-(2-Methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediamine hydrochloride; N4-isobutyl-N2-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine hydrochloride. Grades: ≥98% by HPLC. CAS No. 1784282-12-7. Molecular formula: C18H22ClN5S. Mole weight: 375.92.
KHS 101 hydrochloride
KHS 101 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
KHS101 hydrochloride
KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3). Uses: Scientific research. Group: Signaling pathways. CAS No. 1784282-12-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10996A.
Khusenol
Khusenol, is a component of Vetiver essential oil which is a highly esteemed basic ingredient of modern perfumery, hvaing a woody, earthy scent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16223-63-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H24O, Molecular Weight: 220.35. US Biological Life Sciences.
Worldwide
Ki16198
Ki16198, the methyl ester of Ki16425, is a potent and orally active LPA receptor antagonist with Kis of 0.34 and 0.93 μM against inositol phosphate production induced by LPA1 and LPA3, respectively. It is effective for pancreatic cancer tumorigenesis and metastasis in vivo. Synonyms: 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonylamino)-3-methyl-5-isoxazolyl)benzylsulfanyl)propanoic acid methyl ester; Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester; KI-16198; KI 16198; Methyl 3-((4-(4-(((1-(2-chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)benzyl)thio)propanoate. Grades: >98%. CAS No. 355025-13-7. Molecular formula: C24H25ClN2O5S. Mole weight: 488.98.
Ki16425
Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6. Synonyms: Ki16425; Ki-16425; Ki 16425. Grades: >98%. CAS No. 355025-24-0. Molecular formula: C23H23ClN2O5S. Mole weight: 474.96.
Ki16425
Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with K i s of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA -induced activation of p42/p44 MAPK [1] [2]. Ki16425 can also inhibit LPA -induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 0719. CAS No. 355025-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13285.
Ki 16425
Ki 16425. Group: Biochemicals. Grades: Purified. CAS No. 355025-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ki20227
Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Synonyms: Ki20227; Ki 20227; Ki-20227. Grades: >98%. CAS No. 623142-96-1. Molecular formula: C24H24N4O5S. Mole weight: 480.54.
Ki 20227
Ki 20227. Group: Biochemicals. Grades: Purified. CAS No. 623142-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ki23057
Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism between Ki23057 and chemotherapeutic agents in drug-resistant cell lines. Synonyms: Ki-23057; Ki 23057; 2-((2-((4-(4-((4-(1,1-Dimethylethyl)phenyl)amino)phenoxy)-6-methoxy-7-quinolinyl)oxy)ethyl)amino)ethanol. Grades: 98%. CAS No. 516523-31-2. Molecular formula: C30H35N3O4. Mole weight: 501.63.
KI-328
KI-328 is a novel KIT inhibitor. KI-328 shows selective potency against KIT kinase for the in vitro kinase assay, and inhibits the growth of wild-type (Wt)- and mutant-KIT-expressing cells, while it has little potency against D816V-KIT. Synonyms: KI 328; KI328. Grades: 98%. CAS No. 930089-25-1. Molecular formula: C25H25N7O3. Mole weight: 471.51.
KI-7
KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC 50 =445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC 50 s of 2390 nM and 2550 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1489263-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131032.
Ki8751
Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFRα and FGFR-2 (IC50 values range from 40 to 170 nM). Synonyms: Ki8751; Ki-8751; Ki 8751. Grades: 0.98. CAS No. 228559-41-9. Molecular formula: C24H18F3N3O4. Mole weight: 469.41.
Ki8751
Ki8751 is a potent VEGFR2 inhibitor with an IC 50 of 0.9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 228559-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12038.
Ki 8751
Ki 8751. Group: Biochemicals. Grades: Purified. CAS No. 228559-41-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Kibdelin A
Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38.
Kibdelin B
Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41.
Kibdelin C1
Kibdelin C1 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C1 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103549-47-9. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43.
Kibdelin C2
Kibdelin C2 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C2 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-85-1. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43.
Kibdelin D
Kibdelin D is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin D is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-86-2. Molecular formula: C81H82Cl4N8O29. Mole weight: 1773.36.
Kibdelone A
It is a potent antitumour metabolite isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. It's cytotoxic. Synonyms: (10S,12S,13R)-4-Chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-77-4. Molecular formula: C29H24ClNO10. Mole weight: 581.96.
Kibdelone B
It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10R,12R,13S)-rel-(+)-4-Chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-78-5. Molecular formula: C29H26ClNO10. Mole weight: 583.97.
Kibdelone C
It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99.
Kidney, Rabbit
Kidney, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences.