A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
KIN1408 is an IRF3 activator with antiviral activity. It induces innate immune gene expression such as MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA). Synonyms: 7-[[4-(Difluoromethoxy)phenyl]-[(5-methoxy-1,3-benzothiazol-2-yl)amino]methyl]quinolin-8-ol. Grades: ≥98%. CAS No. 1903800-11-2. Molecular formula: C25H19F2N3O3S. Mole weight: 479.5.
Kinamycin A is produced by the strain of Str. murayamaensis. Kinamycin A has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0505520; 2,3,4-Tri(acetyloxy)-1,2,3,4,6,11-hexahydro-1,7-dihydroxy-3-methyl-6,11-dioxo-5H-benzo(b)carbazole-5-nitrile; 1,2,3-Tris(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-12-9. Molecular formula: C24H20N2O10. Mole weight: 496.42.
Kinamycin B
Kinamycin B is produced by the strain of Str. murayamaensis. Kinamycin B has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0503790; (1R,2R,3R,4S)-2-acetyloxy-11-diazonio-1,3,4,10-tetrahydroxy-2-methyl-9-oxo-3,4-dihydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-13-0. Molecular formula: C20H16N2O8. Mole weight: 412.35.
Kinase Inhibitor Library
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1600. Categories: Kinase Inhibitor Libraries.
Kinase(phosphorylating), protein, cPKC
Kinase(phosphorylating), protein, cPKC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EC 2.7.1.37;PROTEIN KINASE, 3':5'-CYCLIC AMP DEPENDENT;PROTEIN KINASE C;PROTEIN KINASE C, RAT BRAIN;PROTEIN KINASE C, CALCIUM- AND LIPID-DEPENDENT;PKC;protein kinase C from rat brain;PROTEIN KINASE C FROM RAT BRAIN, 5 U/VIAL*. Product Category: Heterocyclic Organic Compound. CAS No. 141436-78-4. Product ID: ACM141436784. Alfa Chemistry ISO 9001:2015 Certified.
Kinesore
Kinesore is an inhibitor of the KLC2-SKIP Interaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 363571-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-112777.
Kinesore
Kinesore is a cell-permeable kinesin-1 modulator. It inhibits kinesin-1 interactions with short linear peptide motifs found in organelle-specific cargo adaptors, but activates kinesin-1's function of controlling microtubule dynamics in cells. Synonyms: 3,5-Dibromo-N'-((2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl)methylene)-4-hydroxybenzohydrazide. Grades: ≥98% by HPLC. CAS No. 363571-83-9. Molecular formula: C20H16Br2N4O4. Mole weight: 536.17.
Kinetensin
Kinetensin (human) is an endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It increases vascular permeability and releases histamine from rat mast cells. It induces histamine release from rat peritoneal mast cells with ED50 value of 10 mM in vitro. Synonyms: Kinetensin (human); Neurotensin-related peptide; H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH; L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine. Grades: ≥95%. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.38.
Kinetin
Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division. Uses: Plant growth regulators. Synonyms: 6-Furfuryladenine; Kinetin; NSC 23119; NSC-23119; NSC23119. Grades: >98%. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21.
Kinetin
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Furfuryladenine; N6-Furfuryladenine. CAS No. 525-79-1. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N0160.
Kinetin
Kinetin was the first cytokinin discovered. It is also adenine-based. Uses: Kinetin was the first cytokinin discovered based on its cell division promotion from a mixture of autoclaved herring sperm. kinetin like other cytokinins promotes cell division, shoot proliferation and organogenesis, aids in the maintenance of the shoot-apical meristem, disrupts apical dominance, and delays senescence. Additional or Alternative Names: 6-Furfurylaminopurine. Product Category: Heterocyclic Organic Compound. Appearance: White to Yellow Crystalline. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21 g/mol. Product ID: ACM525791. Alfa Chemistry ISO 9001:2015 Certified.
Kinetin
A cell division factor found in various plant parts and in yeast. A plant growth regulator. Augments growth of microbial cultures. Group: Biochemicals. Alternative Names: N-(2-Furanylmethyl)-. Grades: Highly Purified. CAS No. 525-79-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Kinetin 99+% (HPLC)
Kinetin 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
Kinetin Riboside
It is used as an anticancer and antiviral agent. Synonyms: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 4338-47-0. Molecular formula: C15H17N5O5. Mole weight: 347.33.
Kinetin riboside-5'-diphosphate sodium salt
Kinetin riboside-5'-monophosphate sodium salt
Kinetin riboside-5'-monophosphate sodium salt, a biomedical compound renowned for its efficacy in combating an array of ailments, emerges as an invaluable panacea for age-related afflictions. Devotedly addressing the challenging sphere of neurodegenerative maladies encompassing Alzheimer's and Parkinson's diseases, this therapeutic treasure trove amalgamates potent antioxidative and anti-inflammatory attributes. Consequently, it orchestrates a symphony of cellular revitalization, ushering in a respite from the ravages of time-induced degeneration. Synonyms: 6-furfurylamino-9-b-D-ribofuranosylpurine-5'-monophosphate disodium monohydrate; [5-[6-(2-furylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid. Grades: ≥ 97% (HPLC). CAS No. 13484-67-8. Molecular formula: C15H16N5Na2O8P·H2O. Mole weight: 489.29.
Kinetin Riboside-5'-monophosphorodichloridate
Kinetin Riboside-5'-monophosphorodichloridate is an intermediate used in the synthesis of Kinetin Riboside-5'-monophosphate, which can be used in pharmacological activity and therapeutic use for structure-related anticancer activity of natural cytokinins. Along with other adenosine derivatives, it can also be used in biological study for manufacture of pharmaceutical formulations for treatment against various parasites, mycoplasmas, other indications and other infections and human immunodeficiency virus inhibition. Molecular formula: C15H16Cl2N5O6P. Mole weight: 464.2.
Used as an anticancer and antiviral agent. Group: Biochemicals. Alternative Names: 6-Furfurylaminopurine Riboside, N6-Furfuryladenosine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Kininogen high molecular weight, Two Chain from human plasma
Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects. Kinsenoside rescues the nucleus pulposus cells (NPCs) viability under oxidative stress and protects against apoptosis, senescence and mitochondrial dysfunction in a Nrf2-dependent way. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone. Product Category: Inhibitors. Appearance: Solid. CAS No. 151870-74-5. Molecular formula: C10H16O8. Mole weight: 264.23. Purity: 0.95. IUPACName: (4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one. Canonical SMILES: C1[C@H](COC1=O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O. Density: 1.59±0.1 g/ml. Product ID: ACM151870745. Alfa Chemistry ISO 9001:2015 Certified.
Kinsenoside
Kinsenoside. Group: Biochemicals. Alternative Names: (+)-Kinsenoside. Grades: Plant Grade. CAS No. 151870-74-5. Pack Sizes: 25mg. Molecular Formula: C10H16O8, Molecular Weight: 264.228999999999. US Biological Life Sciences.
Worldwide
K ir1.1 Inhibitor, VU591
The Kir1.1 Inhibitor, VU591 controls the biological activity of Kir1.1. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable, benzoimidazole, renal outer medullary potassium channel (ROMK) blocker that selectively inhibits inward rectifier potassium channel, Kir1K.1 (IC50=240nM), in HEK-293 cells. At 10uM, it displays no effect on Kir2.1, Kir2.3, Kir4.1, and Kir7.1, with 150-fold selectivity over Kir6.2. In addition, it exhibits a modest off-target effect on the GABAA receptor (IC50=6.2uM) among a panel of cardiac and central nervous system ion channels and receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Kir2.1 Inhibitor, ML133 - CAS 185669-79-8
The Kir2.1 Inhibitor, ML133, also referenced under CAS 185669-79-8, controls the biological activity of Kir2.1. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable, renal outer medullary potassium (ROMK) blocker that is shown to inhibit inward rectifier potassium channel, Kir2.1 (IC50=1.8uM and 290nM, at pH 7.4 and pH 8.5, respectively). It exhibits little selectivity against other members of the Kir2.x family, but has no effect on Kir1.1 (IC50 >300uM) and displays weak activity for Kir4.1 and Kir7.1 (IC50=76uM and 33uM, respectively). It is reported to be assayed in 218 MLPCN HTS campaigns, demonstrating activity in only two assays that are not based on Kir2.1. Furthermore, it displays a relatively clean profile in a radioligand binding panel of 68 GPCRs, ion channels and transporters. Group: Biochemicals. Grades: Highly Purified. CAS No. 185669-79-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
KIRA6
KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Synonyms: KIRA6; KIRA-6; KIRA 6; 1-[4-(8-amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea; 1-(4-(8-amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; KIRA analog, 2. CAS No. 1589527-65-0. Molecular formula: C28H25F3N6O. Mole weight: 518.53.
KIRA-7
KIRA-7, an imidazopyrazine compound, binds the IRE1α kinase ( IC 50 of 110 nM) to allosterically inhibit its RNase activity. KIRA-7 has an anti-fibrotic effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1937235-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124646.
Kira8
Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC 50 of 5.9 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG-18. CAS No. 1630086-20-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114368.
Kirenol
Kirenol. Group: Biochemicals. Grades: Plant Grade. CAS No. 52659-56-0. Pack Sizes: 20mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences.
Worldwide
Kirromycin
Kirromycin is an antibiotic originally isolated from Streptomyces. It was shown to inhibit protein biosynthesis via acting on elongation factor Tu (EF-Tu). Synonyms: Mocimycin; Delvomycin. Grades: ≥95%. CAS No. 50935-71-2. Molecular formula: C43H60N2O12. Mole weight: 796.94.
Antibiotic. Member of the elfermycin group. Antibacterial. Protein biosynthesis inhibitor. Specifically interacts with the bacterial elongation factor EF-Tu and prevents the release of EF-Tu from the bacterial ribosome after GTP hydrolysis. In the absence of ribosomes it induces EF-Tu-dependent hydrolysis of GTP. Animal growth promoter used in poultry breeding. Group: Biochemicals. Grades: Highly Purified. CAS No. 50935-71-2. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Kirrothricin
Kirrothricin is originally isolated from Str. cinnamomeus Tu89. It has antibacterial action, but no activity to subtilis, Escherichia coli and fungi. Synonyms: 2H-Pyran-2-acetamide, N-((2E,4E,6S,7S,9S,10E,12E,14E,16E)-8,9-dihydroxy-6-methoxy-5,7,17-trimethyl-18-oxo-18-(1,2,5,6-tetrahydro-4-hydroxy-1-methyl-2-oxo-3-pyridinyl)-2,4-dihydroxy-5,5-dimethyl-6-((1E,3Z)-1,3-pentadienyl)-, (alphaS,2S,4S,6S)-. CAS No. 79190-00-4. Molecular formula: C44H64N2O10. Mole weight: 780.98.
Kisspeptin-10
Kisspeptin-10, also called Metastin (45-54), is a potent vasoconstrictor and endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Synonyms: Metastin (45-54); Kp-10; H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide; KISS1; Kisspeptin 10 (human). Grades: ≥95%. CAS No. 374675-21-5. Molecular formula: C63H83N17O14. Mole weight: 1302.44.
Kisspeptin 10 (dog)
Kisspeptin 10 (dog) is an endogenous ligand for the canine KISS1 receptor. It stimulates section of follicle stimulating hormone, estradiol and luteinizing hormone in vivo. Molecular formula: C65H87N17O14. Mole weight: 1330.51.
Kisspeptin-10, human
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression [1]. Uses: Scientific research. Group: Peptides. CAS No. 374675-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0254.
Kisspeptin 10 (rat)
Kisspeptin 10 (rat) is an endogenous ligand for the rodent KISS1 receptor. CAS No. 478507-53-8. Molecular formula: C63H83N17O15. Mole weight: 1318.45.
Kisspeptin-10, rat acetate
Kisspeptin-10, rat acetate is an endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54). Synonyms: H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2.CH3CO2H; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-tyrosinamide acetic acid; Rodent kiss-10Y acetate; Rodent kisspeptin 10Y acetate; Kisspeptin-10 (rat) acetate. Grades: ≥95%. Molecular formula: C65H87N17O17. Mole weight: 1378.45.
Kisspeptin-10 Trifluoroacetate
Kisspeptin-10 Trifluoroacetate is a potent vasoconstrictor and endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Synonyms: Kisspeptin-10 TFA; Metastin (45-54) TFA; Kp-10 TFA; H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2.TFA; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide Trifluoroacetate; KISS1 Trifluoroacetate; Kisspeptin 10 (human) Trifluoroacetate. Grades: >98%. Molecular formula: C63H83N17O14.C2HF3O2. Mole weight: 1416.46.
Kisspeptin 234
Kisspeptin 234 is a kisspeptin-10 analog and is used as a kisspeptin receptor antagonist. It inhibits kisspeptin-10 stimulation of inositol phosphate with IC50 value of 7 nM and release of gonadotrophin-releasing hormone. Synonyms: Ac-D-Ala-Asn-Trp-Asn-Gly-Phe-Gly-D-Trp-Arg-Phe-NH2; N-acetyl-D-alanyl-L-asparagyl-L-tryptophyl-L-asparagyl-glycyl-L-phenylalanyl-glycyl-D-tryptophyl-L-arginyl-L-phenylalaninamide. Grades: >98%. CAS No. 1145998-81-7. Molecular formula: C63H78N18O13. Mole weight: 1295.42.
Kisspeptin 234 TFA
Kisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1848962-29-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1196A.
Kisspeptin-54 (27-54) (human)
Kisspeptin-54 (27-54) (human) is an LRF-amide motif containing a fragment of malignant melanoma metastasis-suppressor KiSS-1, that binds to human GPR54, a G-protein-coupled receptor. Compared with malignant melanoma metastasis-suppressor Kisspeptin-10, it shows lower agonistic potency to AXOR12. Synonyms: KiSS-1 (94-121) (human); H-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-glutaminyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-asparagyl-L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide; Metastin (27-54) (human); Malignant melanoma metastasis-Suppressor KiSS-1 (94-121) (human). Grades: ≥95% by HPLC. CAS No. 1135442-77-1. Molecular formula: C149H226N42O39. Mole weight: 3229.65.
Kisspeptin-54(human)
Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with K i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Peptides. Alternative Names: Metastin(human). CAS No. 374683-24-6. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P1022.
Kisspeptin-54 (human) trifluoroacetate salt
Kisspeptin-54 is an endogenous ligand for the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors respectively). It was shown to stimulate the hypothalamic-pituitary-gonadal (HPG) axis in animal models and humans. Synonyms: Metastin (human). Grades: ≥95%. Molecular formula: C258H401N79O78·xCF3COOH. Mole weight: 5857.43.
Kistamicin A
Kistamicin A is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 3.6 and 44. It also has anti-gram-positive bacterial effects. Synonyms: Kistamycin A. CAS No. 155683-50-4. Molecular formula: C61H51ClN8O15. Mole weight: 1171.55.
Kistamicin B
Kistamicin B is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 1.8 and 30. Synonyms: Kistamycin B. CAS No. 155683-51-5. Molecular formula: C70H60ClN9O16. Mole weight: 1318.73.
KIT-6
KIT-6. Group: Kit-6. CAS No. 12173-28-3. Pack Sizes: 10 g.
Kitamycin A
It is originally isolated from Strptomyces sp. K385. Kitamycin A can inhibit the activity of plant growth. Molecular formula: C23H32N2O8. Mole weight: 464.51.
Kit for Creating Hydrophilic PDMS Surface
Kit for Creating Hydrophilic PDMS Surface. Group: Self assembly and lithography.
Kiwifruit concentrate powder
Kiwifruit concentrate powder contains a naturally potent proteolytic enzyme, actinidin, which enhances protein digestion. In-vitro studies have shown that actinidin enhances the digestion of a number of different food proteins, including soy, red meat, milk, gluten and gliaden. Kiwifruit concentrate powder may also help to improve gut motility, which is an important contributor to improved bowel function. The active enzyme content of Kiwifruit concentrate powder is protected by specialised pre-processing and freeze drying techniques which maintain optimal temperature and pH conditions. Group: Others. Activity: >20,000 u/g. Appearance: green to brown powder. Form: Freeze dried powder. Source: green kiwifruit. Actinidin; Kiwifruit concentrate powder; Kiwifruit powder. Cat No: KCP-001.
Kiwi Powder
Kiwi fruit powder is made from fresh kiwi (Actinidia Chinensis), adopt the advanced spray drying technology. Kiwi juice powder is a rich source of vitamin C and vitamin A. Kiwi fruit powder can be used for drinks, health care products, baby food, puffed food, baking food, ice cream, and oatmeal. Group: Others. Kiwi Powder; Actinidia chinensis. Cat No: EXTC-083.
KJ Pyr 9 is a cell-permeable inhibitor of c-Myc (Kd = 6.5 nM) that disrupts Myc-Max interaction. Uses: Disrupts myc-max interaction. Synonyms: KJ-Pyr-9; KJPyr-9; KJ Pyr-9; KJ-Pyr9; KJPyr9; KJ Pyr9; 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide. Grades: ≥98%. CAS No. 581073-80-5. Molecular formula: C22H15N3O4. Mole weight: 385.4.
KKII5
KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6381-55-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W488004.
KKL-10
KKL-10 is a small-molecule ribosome rescue inhibitor with exceptional antimicrobial activity against both attenuated and fully virulent strains of F. tularensis in vitro and during ex vivo infection. Synonyms: KKL-10; KKL 10; KKL10. 5-bromo-N-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carboxamide; 5-bromo-N-(5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thiophene-2-carboxamide; 5-bromo-N-[5-(p-tolyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carboxamide. CAS No. 952849-76-2. Molecular formula: C14H10BrN3O2S. Mole weight: 364.22.
KKL-35
KKL-35 is a trans-translation tagging reaction inhibitor (IC50= 0.9 μM), thereby inhibiting bacterial growth by blocking ribosome rescue. Synonyms: KKL-35; KKL 35; KKL35; 4-chloro-N-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]benzamide; F1374-0110; 4-chloro-N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)benzamide. CAS No. 865285-29-6. Molecular formula: C15H9ClFN3O2. Mole weight: 317.7.
KKL-40 is a small molecule inhibitor that targets the trans-transcription process and is effective against methicillin-sensitive and -resistant Staphylococcus aureus (S. aureus) as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 synergizes with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not synergize with other antibiotics such as daptomycin, kanamycin, or erythromycin. Trans-transcription is an extreme form of recoding, and KKL-40 inhibits trans-transcription but is nontoxic to HeLa cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865285-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116863.
KL001
KL001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. In combination with mathematical modeling, our studies using KL001 revealed that CRY1 and CRY2 share a similar functional role in the period regulation. Furthermore, KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KL001; KL-001; KL 001. Product Category: Others. Appearance: Solid powder. CAS No. 309928-48-1. Molecular formula: C21H22N2O4S. Mole weight: 398.48. Purity: >98%. IUPACName: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide. Canonical SMILES: CS(=O)(N(CC(O)CN1C2=C(C3=C1C=CC=C3)C=CC=C2)CC4=CC=CO4)=O. Product ID: ACM309928481. Alfa Chemistry ISO 9001:2015 Certified. Categories: Kl2017.
KL001
KL001 is a small molecule that specifically interacts with cryptochrome (CRY), blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 fibroblasts without altering casein kinase activity. Uses: Cryptochrome protein (cry) stabilizer. Synonyms: KL 001; KL-001; N-(3-(9H-carbazol-9-yl)-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide. Grades: ≥98%. CAS No. 309928-48-1. Molecular formula: C21H22N2O4S. Mole weight: 398.48.
KL001. Group: Biochemicals. Alternative Names: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide. Grades: Highly Purified. CAS No. 309928-48-1. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C21H22N2O4S, Molecular Weight: 398.48. US Biological Life Sciences.
Worldwide
KL 001
KL 001. Group: Biochemicals. Grades: Purified. CAS No. 309928-48-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
KL002
KL002. Group: Biochemicals. Alternative Names: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-iodophenyl)-methanesulfonamide. Grades: Highly Purified. CAS No. 439141-72-7. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C22H21IN2O3S, Molecular Weight: 520.38. US Biological Life Sciences.
Worldwide
KL-11743
KL-11743 is a potent, orally active and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90 and 68 nM for GLUT1, GLUT2, GLUT3 and GLUT4, respectively. It specifically blocks glucose metabolism and induces cell death in concert with electron transport inhibitors. Synonyms: NSC783733; Acetamide, 2-[3-[6-ethoxy-4-[[4-(1H-pyrazol-4-yl)phenyl]amino]-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-. Grades: ≥98%. CAS No. 1369452-53-8. Molecular formula: C30H30N6O3. Mole weight: 522.60.
KL1333
KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800405-30-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128895.
KL-50
KL-50 is a selective toxin toward tumors that lack the DNA repair protein O 6 -methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O 6 -alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1161826-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164496.