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| Product | Description | |
|---|---|---|
| KHS101 hydrochloride | KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3). Uses: Scientific research. Group: Signaling pathways. CAS No. 1784282-12-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10996A. |  |
| Khusenol | Khusenol, is a component of Vetiver essential oil which is a highly esteemed basic ingredient of modern perfumery, hvaing a woody, earthy scent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16223-63-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H24O, Molecular Weight: 220.35. US Biological Life Sciences. |  Worldwide |
| Ki16198 | Ki16198, the methyl ester of Ki16425, is a potent and orally active LPA receptor antagonist with Kis of 0.34 and 0.93 μM against inositol phosphate production induced by LPA1 and LPA3, respectively. It is effective for pancreatic cancer tumorigenesis and metastasis in vivo. Synonyms: 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonylamino)-3-methyl-5-isoxazolyl)benzylsulfanyl)propanoic acid methyl ester; Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester; KI-16198; KI 16198; Methyl 3-((4-(4-(((1-(2-chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)benzyl)thio)propanoate. Grades: >98%. CAS No. 355025-13-7. Molecular formula: C24H25ClN2O5S. Mole weight: 488.98. |  |
| Ki16425 | Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with K i s of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA -induced activation of p42/p44 MAPK [1] [2]. Ki16425 can also inhibit LPA -induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 0719. CAS No. 355025-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13285. | |
| Ki16425 | Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6. Synonyms: Ki16425; Ki-16425; Ki 16425. Grades: >98%. CAS No. 355025-24-0. Molecular formula: C23H23ClN2O5S. Mole weight: 474.96. | |
| Ki 16425 | Ki 16425. Group: Biochemicals. Grades: Purified. CAS No. 355025-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ki20227 | Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Synonyms: Ki20227; Ki 20227; Ki-20227. Grades: >98%. CAS No. 623142-96-1. Molecular formula: C24H24N4O5S. Mole weight: 480.54. | |
| Ki 20227 | Ki 20227. Group: Biochemicals. Grades: Purified. CAS No. 623142-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ki23057 | Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism between Ki23057 and chemotherapeutic agents in drug-resistant cell lines. Synonyms: Ki-23057; Ki 23057; 2-((2-((4-(4-((4-(1,1-Dimethylethyl)phenyl)amino)phenoxy)-6-methoxy-7-quinolinyl)oxy)ethyl)amino)ethanol. Grades: 98%. CAS No. 516523-31-2. Molecular formula: C30H35N3O4. Mole weight: 501.63. | |
| KI-328 | KI-328 is a novel KIT inhibitor. KI-328 shows selective potency against KIT kinase for the in vitro kinase assay, and inhibits the growth of wild-type (Wt)- and mutant-KIT-expressing cells, while it has little potency against D816V-KIT. Synonyms: KI 328; KI328. Grades: 98%. CAS No. 930089-25-1. Molecular formula: C25H25N7O3. Mole weight: 471.51. | |
| KI-7 | KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC 50 =445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC 50 s of 2390 nM and 2550 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1489263-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131032. | |
| Ki8751 | Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFRα and FGFR-2 (IC50 values range from 40 to 170 nM). Synonyms: Ki8751; Ki-8751; Ki 8751. Grades: 0.98. CAS No. 228559-41-9. Molecular formula: C24H18F3N3O4. Mole weight: 469.41. | |
| Ki8751 | Ki8751 is a potent VEGFR2 inhibitor with an IC 50 of 0.9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 228559-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12038. | |
| Ki 8751 | Ki 8751. Group: Biochemicals. Grades: Purified. CAS No. 228559-41-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Kibdelin A | Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38. | |
| Kibdelin B | Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41. | |
| Kibdelin C1 | Kibdelin C1 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C1 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103549-47-9. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin C2 | Kibdelin C2 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C2 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-85-1. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin D | Kibdelin D is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin D is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-86-2. Molecular formula: C81H82Cl4N8O29. Mole weight: 1773.36. | |
| Kibdelone A | It is a potent antitumour metabolite isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. It's cytotoxic. Synonyms: (10S,12S,13R)-4-Chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-77-4. Molecular formula: C29H24ClNO10. Mole weight: 581.96. | |
| Kibdelone B | It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10R,12R,13S)-rel-(+)-4-Chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-78-5. Molecular formula: C29H26ClNO10. Mole weight: 583.97. | |
| Kibdelone C | It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99. | |
| Kidamycin | Heterocyclic Organic Compound. CAS No. 11072-82-5. Molecular formula: C39H48N2O9. Catalog: ACM11072825. |  |
| Kidney, Rabbit | Kidney, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences. | Worldwide |
| Kidney-targeted In Vivo Kit | Kidney-targeted in vivo transfection kit. Functionally tested in mice tissue-targeted delivery of siRNA and pDNA via IV,IP,IT administrations. Kit includes: In vivo delivery reagent. Transfection Enhancer reagent. Protocol for mice and rats. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 5071. |  Nevada, Texas, USA |
| kievitone hydratase | The enzyme from Fusarium sp. hydrates the methylbutenyl sidechain of the isoflavonoid phytoalexins, thus reducing their toxicity. Group: Enzymes. Synonyms: KHase; kievitone-hydrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.95. CAS No. 70431-10-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5079; kievitone hydratase; EC 4.2.1.95; 70431-10-6; KHase; kievitone-hydrate hydro-lyase. Cat No: EXWM-5079. |  |
| Kif15-IN-1 | Kif15-IN-1 is a potent Kif15 kinesin inhibitor, which inhibits cellular proliferation in tumor cell lines. Synonyms: KIF15-IN-1; KIF15IN-1; KIF15-IN1; KIF15IN1; KIF15 IN 1. Grades: >98%. CAS No. 672926-32-8. Molecular formula: C20H22N4O5S. Mole weight: 430.48. | |
| Kif15-IN-2 | Kif15-IN-2 is a potent Kif15 kinesin inhibitor, which inhibits cellular proliferation in tumor cell lines. Synonyms: KIF15-IN-2; KIF15IN-2; KIF15-IN2; KIF15IN2; KIF15 IN 2. Grades: >98%. CAS No. 672926-33-9. Molecular formula: C20H20N6O4S. Mole weight: 440.48. | |
| Kifunensine | Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense. It is a potent inhibitor of the mannosidase I enzyme. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Kifunensine | Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: FR-900494. CAS No. 109944-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19332. | |
| Kifunensine | Heterocyclic Organic Compound. Alternative Names: (5R,8aS)-1,5,6,7,8,8a-Hexahydro-6β,7α,8α-trihydroxy-5α-(hydroxymethyl)imidazo[1,2-a]pyridine-2,3-dione. CAS No. 109944-15-2. Molecular formula: C8H12N2O6. Mole weight: 232.19. Purity: 95%+. Catalog: ACM109944152. | |
| Kifunensine diacetonide | Kifunensine diacetonide, an indispensable biomedicine tool revered for its potency, takes center stage in the realm of therapeutic interventions for glycoprotein-based diseases. Its remarkable prowess lies in its profound inhibition of α-mannosidase I, thereby triggering the unprecedented accumulation of high-mannose glycoproteins. This profound offering stands as a gateway to unraveling novel revelations surrounding afflictions including cancer, viral infections, and genetic disorders intimately entwined with the intricate world of protein glycosylation. Synonyms: (3aS,3bR,7aR,11aS,11bR)-Hexahydro-2,2,5,5-tetramethyl-7H-[1,3]dioxino[4,5-e]-1,3-dioxolo[4,5-c]imidazo[1,2-a]pyridine-9,10-dione. CAS No. 134234-43-8. Molecular formula: C14H20N2O6. Mole weight: 312.32. | |
| Kifunensine diacetonide | Kifunensine diacetonide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kigamicin A | Kigamicin A is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C34H35NO13. Mole weight: 665.64. | |
| Kigamicin B | Kigamicin B is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C40H45NO15. Mole weight: 779.78. | |
| Kigamicin C | Kigamicin C was discovered by an anti-austerity strategy targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blocking of the activation of PKB/Akt caused by the withdrawal of nutrients. Active in vivo against a human pancreatic cancer xenograft model. Also inhibits the growth of Gram-positive bacteria including Staphylococcus aureus MRSA, but not active against Gram-negative bacteria. Group: Biochemicals. Grades: Highly Purified. CAS No. 680571-51-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Kigamicin C | Selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions; active in vivo against a human pancreatic cancer xenograft model; also inhibits the growth of gram positive bacteria including MRSA, but is not active against gram negative bacteria. Synonyms: (1S, 3R, 4S, 8aR, 11aR)-3-[[(2S, 5S, 6R)-5-[(2, 6-dideoxy-3-O-methyl-b-D-arabinohexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1, 2, 3, 4, 8a, 9, 11, 11a, 13, 14-decahydro-1, 4, 17, 18-tetrahydroxy-11a-methyl-oxazolo[3, 2-b]xantheno[4', 3', 2':4, 5][1, 3]benzodioxino[7, 6-g]isoquinoline-16, 19-dione. Grades: >98% by HPLC. CAS No. 680571-51-1. Molecular formula: C41H47NO16. Mole weight: 809.81. | |
| Kigamicin D | Kigamicin D is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. It also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL. Synonyms: 1,2,3a,4,6,7,10,11,12,13-Decahydro-11-[[5-[[5-[(tetrahydro-5-hydroxy-4-methoxy-6-methyl-2H-pyran-2-yl)oxy]tetrahydro-4-methoxy-6-methyl-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-10,13,15,16-tetrahydroxy-3a-methyl-7,8-(methylenedioxy)-17a-aza-3,9-dioxa-17aH-cyclopenta[b]hexaphene-14,17-dione. Molecular formula: C48H59NO19. Mole weight: 953.98. | |
| Kihadanin A | Terpenoids. CAS No. 125276-62-2. Molecular formula: C26H30O9. Mole weight: 486.5. Appearance: Powder. Purity: 0.98. Canonical SMILES: CC1 (C2CC (=O)C3 (C (C2 (C=CC (=O)O1)C)CCC4 (C35C (O5)C (=O)OC4C6=CC (=O)OC6O)C)C)C. Catalog: ACM125276622. | |
| Kihadanin B | Kihadanin B is a citrus limonoid that can be purified from the peels of immature Citrus unshiu. Kihadanin B suppresses adipogenesis through repression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes. Group: Inhibitors. CAS No. 73793-68-7. Molecular formula: C26H30O9. Mole weight: 486.5. Appearance: Powder. Purity: 0.98. Canonical SMILES: CC1 (C2CC (=O)C3 (C (C2 (C=CC (=O)O1)C)CCC4 (C35C (O5)C (=O)OC4C6=CC (OC6=O)O)C)C)C. Catalog: ACM73793687. | |
| Kijanimicin | A tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin; contains an unusual nitroaminoglycoside; a potent antibacterial, antimalarial and antitumour active; inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). Synonyms: NSC 329515; Sch 25663. Grades: >99% by HPLC. CAS No. 78798-08-0. Molecular formula: C67H100N2O24. Mole weight: 1317.51. | |
| Kijanimicin (Antibiotic Sch 25663) | Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor activity. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. While tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Alternative Names: Antibiotic Sch 25663. Grades: Highly Purified. CAS No. 78798-08-0. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Synonyms: KIN-1148; KIN 1148; KIN1148; N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide. Grades: ≥98% (HPLC). CAS No. 1428729-56-9. Molecular formula: C19H11N3OS2. Mole weight: 361.44. | |
| KIN1400 | KIN1400 is an IRF3 activator with antiviral activity. It induces IRF3-dependent innate immune gene expression such as RIG-1, MDA5, IFIT1, IFIT2, IFITM1, OAS3, and Mx1 in THP-1 cells stimulated with phorbol 12-myristate 13-acetate (PMA). It also inhibits replication of HCV, West Nile virus, and Paramyxoviridae (RCV, NV). Synonyms: 7- ( (benzo[d]thiazol-2-ylamino) (4- (difluoromethoxy) phenyl) methyl) quinolin-8-ol. Grades: ≥98%. CAS No. 446826-86-4. Molecular formula: C24H17F2N3O2S. Mole weight: 449.5. | |
| KIN1408 | KIN1408 is an IRF3 activator with antiviral activity. It induces innate immune gene expression such as MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA). Synonyms: 7-[[4-(Difluoromethoxy)phenyl]-[(5-methoxy-1,3-benzothiazol-2-yl)amino]methyl]quinolin-8-ol. Grades: ≥98%. CAS No. 1903800-11-2. Molecular formula: C25H19F2N3O3S. Mole weight: 479.5. | |
| Kinamycin A | Kinamycin A is produced by the strain of Str. murayamaensis. Kinamycin A has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0505520; 2,3,4-Tri(acetyloxy)-1,2,3,4,6,11-hexahydro-1,7-dihydroxy-3-methyl-6,11-dioxo-5H-benzo(b)carbazole-5-nitrile; 1,2,3-Tris(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-12-9. Molecular formula: C24H20N2O10. Mole weight: 496.42. | |
| Kinamycin B | Kinamycin B is produced by the strain of Str. murayamaensis. Kinamycin B has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0503790; (1R,2R,3R,4S)-2-acetyloxy-11-diazonio-1,3,4,10-tetrahydroxy-2-methyl-9-oxo-3,4-dihydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-13-0. Molecular formula: C20H16N2O8. Mole weight: 412.35. | |
| Kinase Inhibitor Library | A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1600. Categories: Kinase Inhibitor Libraries. |  |
| Kinesore | Kinesore is a cell-permeable kinesin-1 modulator. It inhibits kinesin-1 interactions with short linear peptide motifs found in organelle-specific cargo adaptors, but activates kinesin-1's function of controlling microtubule dynamics in cells. Synonyms: 3,5-Dibromo-N'-((2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl)methylene)-4-hydroxybenzohydrazide. Grades: ≥98% by HPLC. CAS No. 363571-83-9. Molecular formula: C20H16Br2N4O4. Mole weight: 536.17. | |
| Kinesore | Kinesore is an inhibitor of the KLC2-SKIP Interaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 363571-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-112777. | |
| Kinetensin | Kinetensin (human) is an endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It increases vascular permeability and releases histamine from rat mast cells. It induces histamine release from rat peritoneal mast cells with ED50 value of 10 mM in vitro. Synonyms: Kinetensin (human); Neurotensin-related peptide; H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH; L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine. Grades: ≥95%. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.38. | |
| Kinetensin | Heterocyclic Organic Compound. Alternative Names: KINETENSIN;KINETENSIN (HUMAN);IARRHPYFL;ILE-ALA-ARG-ARG-HIS-PRO-TYR-PHE-LEU;H-ILE-ALA-ARG-ARG-HIS-PRO-TYR-PHE-LEU-OH;NEUROTENSIN-RELATED PEPTIDE;NRP. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.3814. Appearance: White lyophilised solid. Purity: 0.96. IUPACName: 2-[[2-[[2-[[1-[2-[[2-[[2-[2-[ (2-amino-3-methylpentanoyl) amino]propanoylamino]-5- (diaminomethylideneamino) pentanoyl]amino]-5- (diaminomethylideneamino) pentanoyl]amino]-3- (1H-imidazol-5-yl) propanoyl]pyrrolidine-2-carbonyl]amino]-3- (4-hydroxyphenyl) propanoyl]. Canonical SMILES: CCC (C)C (C (=O)NC (C)C (=O)NC (CCCN=C (N)N)C (=O)NC (CCCN=C (N)N)C (=O)NC (CC1=CN=CN1)C (=O)N2CCCC2C (=O)NC (CC3=CC=C (C=C3)O)C (=O)NC (CC4=CC=CC=C4)C (=O)NC (CC (C)C)C (=O)O)N. Density: 1.41 g/cm³. Catalog: ACM103131697. | |
| Kinetin | Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Furfuryladenine; N6-Furfuryladenine. CAS No. 525-79-1. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N0160. | |
| Kinetin | Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division. Uses: Plant growth regulators. Synonyms: 6-Furfuryladenine; Kinetin; NSC 23119; NSC-23119; NSC23119. Grades: >98%. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21. | |
| Kinetin | A cell division factor found in various plant parts and in yeast. A plant growth regulator. Augments growth of microbial cultures. Group: Biochemicals. Alternative Names: N-(2-Furanylmethyl)-. Grades: Highly Purified. CAS No. 525-79-1. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Kinetin | Kinetin was the first cytokinin discovered. It is also adenine-based. Uses: Kinetin was the first cytokinin discovered based on its cell division promotion from a mixture of autoclaved herring sperm. kinetin like other cytokinins promotes cell division, shoot proliferation and organogenesis, aids in the maintenance of the shoot-apical meristem, disrupts apical dominance, and delays senescence. Group: Heterocyclic organic compound. Alternative Names: 6-Furfurylaminopurine. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21 g/mol. Appearance: White to Yellow Crystalline. Catalog: ACM525791. | |
| Kinetin 99+% (HPLC) | Kinetin 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| Kinetin Riboside | It is used as an anticancer and antiviral agent. Synonyms: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 4338-47-0. Molecular formula: C15H17N5O5. Mole weight: 347.33. | |
| Kinetin riboside-5'-diphosphate sodium salt | | |
| Kinetin riboside-5'-monophosphate sodium salt | Kinetin riboside-5'-monophosphate sodium salt, a biomedical compound renowned for its efficacy in combating an array of ailments, emerges as an invaluable panacea for age-related afflictions. Devotedly addressing the challenging sphere of neurodegenerative maladies encompassing Alzheimer's and Parkinson's diseases, this therapeutic treasure trove amalgamates potent antioxidative and anti-inflammatory attributes. Consequently, it orchestrates a symphony of cellular revitalization, ushering in a respite from the ravages of time-induced degeneration. Synonyms: 6-furfurylamino-9-b-D-ribofuranosylpurine-5'-monophosphate disodium monohydrate; [5-[6-(2-furylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid. Grades: ≥ 97% (HPLC). CAS No. 13484-67-8. Molecular formula: C15H16N5Na2O8P·H2O. Mole weight: 489.29. | |
| Kinetin Riboside-5'-monophosphorodichloridate | Kinetin Riboside-5'-monophosphorodichloridate is an intermediate used in the synthesis of Kinetin Riboside-5'-monophosphate, which can be used in pharmacological activity and therapeutic use for structure-related anticancer activity of natural cytokinins. Along with other adenosine derivatives, it can also be used in biological study for manufacture of pharmaceutical formulations for treatment against various parasites, mycoplasmas, other indications and other infections and human immunodeficiency virus inhibition. Molecular formula: C15H16Cl2N5O6P. Mole weight: 464.2. | |
| Kinetin riboside-5'-triphosphate sodium salt | | |
| Kinetin Riboside (6-Furfurylaminopurine Riboside, N6-Furfuryladenosine) | Used as an anticancer and antiviral agent. Group: Biochemicals. Alternative Names: 6-Furfurylaminopurine Riboside, N6-Furfuryladenosine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Kinsenoside | Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects. Kinsenoside rescues the nucleus pulposus cells (NPCs) viability under oxidative stress and protects against apoptosis, senescence and mitochondrial dysfunction in a Nrf2-dependent way. Group: Inhibitors. Alternative Names: (4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone. CAS No. 151870-74-5. Molecular formula: C10H16O8. Mole weight: 264.23. Appearance: Solid. Purity: 0.95. IUPACName: (4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one. Canonical SMILES: C1[C@H] (COC1=O)O[C@H]2[C@@H] ([C@H] ([C@@H] ([C@H] (O2)CO)O)O)O. Density: 1.59±0.1 g/ml. Catalog: ACM151870745. | |
| Kinsenoside | Kinsenoside. Group: Biochemicals. Alternative Names: (+)-Kinsenoside. Grades: Plant Grade. CAS No. 151870-74-5. Pack Sizes: 25mg. Molecular Formula: C10H16O8, Molecular Weight: 264.228999999999. US Biological Life Sciences. | Worldwide |
| Kir1.1 Inhibitor, VU591 (Inward Rectifier Potassium Channel Kir1.1 Blocker, VU591) | A cell-permeable, benzoimidazole, renal outer medullary potassium channel (ROMK) blocker that selectively inhibits inward rectifier potassium channel, Kir1K.1 (IC50=240nM), in HEK-293 cells. At 10uM, it displays no effect on Kir2.1, Kir2.3, Kir4.1, and Kir7.1, with 150-fold selectivity over Kir6.2. In addition, it exhibits a modest off-target effect on the GABAA receptor (IC50=6.2uM) among a panel of cardiac and central nervous system ion channels and receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Kir2.1 Inhibitor, ML133 (Inward Rectifier Potassium Channel Blocker, ML133) | A cell-permeable, renal outer medullary potassium (ROMK) blocker that is shown to inhibit inward rectifier potassium channel, Kir2.1 (IC50=1.8uM and 290nM, at pH 7.4 and pH 8.5, respectively). It exhibits little selectivity against other members of the Kir2.x family, but has no effect on Kir1.1 (IC50 >300uM) and displays weak activity for Kir4.1 and Kir7.1 (IC50=76uM and 33uM, respectively). It is reported to be assayed in 218 MLPCN HTS campaigns, demonstrating activity in only two assays that are not based on Kir2.1. Furthermore, it displays a relatively clean profile in a radioligand binding panel of 68 GPCRs, ion channels and transporters. Group: Biochemicals. Grades: Highly Purified. CAS No. 185669-79-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| KIRA6 | KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Synonyms: KIRA6; KIRA-6; KIRA 6; 1-[4-(8-amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea; 1-(4-(8-amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; KIRA analog, 2. CAS No. 1589527-65-0. Molecular formula: C28H25F3N6O. Mole weight: 518.53. | |
| KIRA-7 | KIRA-7, an imidazopyrazine compound, binds the IRE1α kinase ( IC 50 of 110 nM) to allosterically inhibit its RNase activity. KIRA-7 has an anti-fibrotic effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1937235-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124646. | |
| Kira8 | Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC 50 of 5.9 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG-18. CAS No. 1630086-20-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114368. | |
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