American Chemical Suppliers
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Product | Description | |
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KX1-004 Quick inquiry Where to buy Suppliers range | KX1-004 is an Src-protein tyrosine kinase inhibitor to reduce cisplatin ototoxicity while preserving its antitumor effect. KX1-004 has been used to protect the cochlea from hazardous noise. Synonyms: KX1-004; KX 1-004; KX1 004. Grades: 0.98. CAS No. 518058-84-9. Molecular formula: C16H13FN2O2. Mole weight: 284.29. | |
KX1-141 Quick inquiry Where to buy Suppliers range | KX1-141 is an Src-protein tyrosine kinase inhibitor, which may reduce cisplatin ototoxicity while preserving its antitumor effect. Synonyms: KX-1-141; KX 1-141; 1H-Indole-2-carboxamide, 7-(3-ethoxyphenyl)-5-fluoro-N-[(3-fluorophenyl)methyl]-. Grades: 98%. CAS No. 1000706-00-2. Molecular formula: C24H20F2N2O2. Mole weight: 406.42. | |
KX2-391 Quick inquiry Where to buy Suppliers range | KX2-391 is an orally bioavailable small molecule Src kinase inhibitor with potential antineoplastic activity. Unlike other Src kinase inhibitors which bind to the ATP-binding site, Src kinase inhibitor KX2-391 specifically binds to the peptide substrate binding site of Src kinase; inhibition of kinase activity may result in the inhibition of primary tumor growth and the suppression of metastasis. Src tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. Uses: Enzyme inhibitors. Synonyms: KX01, KX-01, KX 01, KX2-391; KX-2-391; KX 2-391; KX2391; KX-2391; KX 2391; Tirbanibulin. CAS No. 897016-82-9. Molecular formula: C26H29N3O3. Mole weight: 431.53. | |
KX2-391 dihydrochloride Quick inquiry Where to buy Suppliers range | KX2-391 2Hcl is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Synonyms: KX2-391 dihydrochloride; 1038395-65-1; KX2-391 (dihydrochloride); Tirbanibulin (dihydrochloride); N-benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]acetamide;dihydrochloride. Grades: >98%. CAS No. 1038395-65-1. Molecular formula: C26H31Cl2N3O3. Mole weight: 504.45. | |
KY02111 Quick inquiry Where to buy Suppliers range | KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling. Synonyms: N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide. Grades: >98%. CAS No. 1118807-13-8. Molecular formula: C18H17ClN2O3S. Mole weight: 376.86. | |
KY02111 Quick inquiry Where to buy Suppliers range | KY02111. Group: Biochemicals. Alternative Names: KY 02111, KY-02111, CHEMBL3186128, HY-13815, S-7828. Grades: Highly Purified. CAS No. 1118807-13-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C18 H17 ClN 2O3, Molecular Weight: 376.9. US Biological Life Sciences. | Worldwide |
KY02111 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1118807-13-8. Pack Sizes: 5MG, 25MG. Mole weight: 376.86. Catalog: AP1118807138. Assay: ≥98% (HPLC). | |
KY 02111 Quick inquiry Where to buy Suppliers range | KY 02111. Group: Biochemicals. Grades: Purified. CAS No. 1118807-13-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
KY 05009 Quick inquiry Where to buy Suppliers range | KY 05009 is an inhibitor of Traf2- and Nck-Interacting Kinase (TNIK; Ki value 100 nM in ATP competitive assay) that attenuates TGF-β1-mediated Wnt and Smad signaling and epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma A549 cells. In addition, KY05009 inhibits TGF-β1-induced phosphorylation of JNK1/2, FAK, Src, and paxillin. Synonyms: KY 05009; KY05009; KY-05009; 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide; 2-anilino-5-[(4-methylbenzoyl)amino]-1,3-thiazole-4-carboxamide. Grades: 99%. CAS No. 1228280-29-2. Molecular formula: C18H16N4O2S. Mole weight: 352.41. | |
KY-1044 Quick inquiry Where to buy Suppliers range | KY-1044 is a novel anti-inducible co-stimulator molecule (ICOS) subclass G1 kappa monoclonal antibody developed for the treatment of cancer. KY-1044 has a dual mechanism of action: stimulating immune cells which are fighting the tumor, while also killing a type of cell known as T regulatory cells (Tregs). Uses: Potential cancer therapy. Synonyms: KY-1044; KY1044; KY1044. | |
KY1220 Quick inquiry Where to buy Suppliers range | KY1220 is a novel inhibitor of the Wnt/ß-catenin pathway, destabilizing both β-catenin and Ras via targeting the Wnt/β-catenin pathway (IC50= 2.1 μM in HEK293 reporter cells). Synonyms: KY1220; KY-1220; KY 1220; (5Z)-5-[[1-(4-nitrophenyl)pyrrol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one. CAS No. 292168-79-7. Molecular formula: C14H10N4O3S. Mole weight: 314.32. | |
KY-226 Quick inquiry Where to buy Suppliers range | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. It significantly reduced plasma glucose, triglyceride, and A1c levels without weight gain in db/db mice. Uses: Enzyme inhibitors. Synonyms: 4-(biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide; BCP32729; EX-A3829. CAS No. 1621673-53-7. Molecular formula: C27H31NO3S2. Mole weight: 481.7. | |
KYA1797K Quick inquiry Where to buy Suppliers range | KYA1797K is a potent, selective and dual inhibitor of Wnt/β-catenin (IC50= 0.75 μM) that significantly decreases reporter activities for the Wnt/β-catenin and MAPK/ERK pathways. Synonyms: potassium;3-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoate. Grades: >98%. CAS No. 1956356-56-1. Molecular formula: C17H11KN2O6S2. Mole weight: 442.51. | |
KYL Quick inquiry Where to buy Suppliers range | KYL. Group: Biochemicals. Grades: Purified. CAS No. 676657-00-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
KYL Quick inquiry Where to buy Suppliers range | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half life in cell culture media. It has the neuroprotective effect. Synonyms: H-Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu-OH; L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine; HY-P2264. Grades: ≥95%. CAS No. 676657-00-4. Molecular formula: C74H108N14O17. Mole weight: 1465.75. | |
KYL acetate Quick inquiry Where to buy Suppliers range | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with a Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with an IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half-life in cell culture media. It has a neuroprotective effect. Synonyms: L-Leucine, L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-, acetate; L-Lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine acetate; KYL peptide acetate; Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu acetate salt. Grades: ≥95%. Molecular formula: C74H108N14O17.C2H4O2. Mole weight: 1525.78. | |
KYL trifluoroacetate salt Quick inquiry Where to buy Suppliers range | ≥95% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 676657-00-4 (free base). Pack Sizes: 1MG. Mole weight: 1465.73 (free base basis). Catalog: ALP676657004. Assay: ≥95% (HPLC). | |
Kyn1-(Des-Trp1) Daptomycin Quick inquiry Where to buy Suppliers range | Kyn1-(Des-Trp1) Daptomycin is a derivative of Daptomycin (D193350), is a cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C71H101N17O27, Molecular Weight: 1624.66. US Biological Life Sciences. | Worldwide |
Kynapcin-12 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Polyozellus multiplex. It has the activity of inhibiting proline endopeptidase (PEP, EC 3.4.21.26) with IC50 of 1.25 μg/mL. Synonyms: kynapcin 12. Molecular formula: C22H18O8. Mole weight: 410.37. | |
Kynapcin-13 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 76.80 μmol/L. It has a little inhibitory effect on other serine proteases. Synonyms: kynapcin 13. Molecular formula: C12H10O7. Mole weight: 266.20. | |
Kynapcin-28 Quick inquiry Where to buy Suppliers range | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 0.98 μmol/L. It has little inhibitory effect on other serine proteases. Synonyms: kynapcin 28. Molecular formula: C19H12O10. Mole weight: 400.29. | |
Kynostatin 272 Quick inquiry Where to buy Suppliers range | Kynostatin 272. Group: Heterocyclic Organic Compound. Alternative Names: kynostatin 272;kynostatin-272|(R)-N-tert-butyl-3-[(2S,3S)-3-[(S)-2-(5-isoquinolinyloxyacetyl)aMino-3-Methylthiopropionyl]aMino-2-hydroxy-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxaMide|KNI-272|(R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(R)-2-(5-isoquinolyloxy-acetyl)aM. Grades: 96%. CAS No. 147318-81-8. Molecular formula: C33H41N5O6S2. Mole weight: 667.848. IUPAC Name: (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[[(2R)-2-[(2-isoquinolin-5-yloxyacetyl)amino]-3-methylsulfanylpropanoyl]amino]-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide. Exact Mass: 667.25000. Boiling Point: 1045.3ºC at 760mmHg. Flash Point: 586ºC. Density: 1.301g/cm3. InChIKey: NJBBLOIWMSYVCQ-VZTVMPNDSA-N. H-Bond Donor: 4. H-Bond Acceptor: 7. | |
Kynuramine dihydrochloride Quick inquiry Where to buy Suppliers range | Kynuramine dihydrochloride. Group: Biochemicals. Alternative Names: 3-Amino-1-(2-aminophenyl)-1-propanone dihydrochloride. Grades: Highly Purified. CAS No. 363-36-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H12N2O·2HCl. US Biological Life Sciences. | Worldwide |
Kynurenic acid Quick inquiry Where to buy Suppliers range | Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainic acid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Synonyms: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17. | |
Kynurenic Acid Quick inquiry Where to buy Suppliers range | Kynurenic Acid. Uses: For analytical and research use. Group: Building Blocks. CAS No. 492-27-3. Pack Sizes: 10MG. IUPAC Name: 4-hydroxyquinoline-2-carboxylic acid. Molecular formula: C10H7NO3. Mole weight: 189.17. Catalog: APS492273. SMILES: OC(=O)c1cc(O)c2ccccc2n1. Format: Neat. Shipping: Room Temperature. | |
Kynurenic Acid Quick inquiry Where to buy Suppliers range | A product of L-Tryptophan metabolism, possessing neuroactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; 4-Hydroxyquinaldinic Acid; Quinurenic Acid; NSC 58973. Grades: Highly Purified. CAS No. 492-27-3. Pack Sizes: 10mg, 100mg, 500mg, 1g. Molecular Formula: C10H7NO3, Melting Point: 256-258°C (dec.). US Biological Life Sciences. | Worldwide |
Kynurenic Acid-d5 Quick inquiry Where to buy Suppliers range | A labeled product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid-d5; 4-Hydroxy-quinaldic Acid-d5; 2-Carboxy-4-hydroxyquinoline-d5; 4-Hydroxyquinaldic Acid-d5; 4-Hydroxyquinaldinic Acid-d5; Quinurenic Acid-d5; NSC 58973-d5. Grades: Highly Purified. CAS No. 350820-13-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Kynurenic Acid-d5 Quick inquiry Where to buy Suppliers range | Kynurenic Acid-d5. Uses: For analytical and research use. Group: Building Blocks. CAS No. 350820-13-2. Pack Sizes: 2.5MG. IUPAC Name: 3,5,6,7,8-pentadeuterio-4-hydroxyquinoline-2-carboxylic acid. Molecular formula: C102H5H2NO3. Mole weight: 194.20. Catalog: APS350820132. SMILES: [2H]c1c ([2H])c ([2H])c2c (O)c ([2H])c (nc2c1[2H])C (=O)O. Format: Neat. Product Type: Stable Isotope Labelled. Shipping: Room Temperature. | |
Kynurenic acid sodium salt Quick inquiry Where to buy Suppliers range | Kynurenic acid sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 2439-2-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Kynurenic acid sodium salt Quick inquiry Where to buy Suppliers range | Kynurenic acid sodium salt is the sodium form of kynurenic acid, which is a broad spectrum EAA antagonist. Synonyms: 4-Hydroxyquinoline-2-carboxylic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 2439-2-3. Molecular formula: C10H6NNaO3. Mole weight: 211.15. | |
Kyotorphin Quick inquiry Where to buy Suppliers range | Kyotorphin is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It is synthesized at nerve terminals and found in the brain and cerebrospinal fluid (CSF). People with persistent pain and alzheimer's disease have lower levels of cerebrospinal fluid. Uses: Analgesics. Synonyms: H-Tyr-Arg-OH; L-tyrosyl-L-arginine; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-5-guanidinopentanoic acid; Arginine, N2-tyrosyl-; L-Arginine, N2-L-tyrosyl-. Grades: ≥95%. CAS No. 70904-56-2. Molecular formula: C15H23N5O4. Mole weight: 337.37. | |
Kyotorphin acetate Quick inquiry Where to buy Suppliers range | Kyotorphin acetate is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It can be used as a biomarker of Alzheimer's disease. Synonyms: H-Tyr-Arg-OH.CH3CO2H; YR.CH3CO2H; L-tyrosyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 212185-19-8. Molecular formula: C15H23N5O4.C2H4O2. Mole weight: 397.43. | |
Kyotorphin acetate salt Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 70904-56-2 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 337.37 (free base basis). Catalog: ALP70904562. Assay: ≥98% (HPLC). | |
Kyowanol M 25265-77-4 Quick inquiry Where to buy Suppliers range | Kyowanol M - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
KYP-2047 Quick inquiry Where to buy Suppliers range | KYP-2047 is a selective Prolyl oligopeptidase inhibitor. And it is also known as prolyl endopeptidase. KYP-2047 can reduce α-synuclein protein levels and aggregate in cellular and animal models of Parkinson's disease. KYP-2047 can clear the α-synuclein aggregates induced by oxidative stress in the neuronal cells. Uses: Parkinson's disease. Synonyms: KYP-2047; KYP2047; KYP 2047. (2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile. Grades: 95%. CAS No. 796874-99-2. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
KYP-2047 Quick inquiry Where to buy Suppliers range | ≥95% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 796874-99-2. Pack Sizes: 5MG, 25MG. Mole weight: 339.43. Catalog: AP796874992. Assay: ≥95% (HPLC). |