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| Product | Description | |
|---|---|---|
| KY1220 | KY1220 is a novel inhibitor of the Wnt/ß-catenin pathway, destabilizing both β-catenin and Ras via targeting the Wnt/β-catenin pathway (IC50= 2.1 μM in HEK293 reporter cells). Synonyms: KY1220; KY-1220; KY 1220; (5Z)-5-[[1-(4-nitrophenyl)pyrrol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one. CAS No. 292168-79-7. Molecular formula: C14H10N4O3S. Mole weight: 314.32. |  |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. It significantly reduced plasma glucose, triglyceride, and A1c levels without weight gain in db/db mice. Uses: Enzyme inhibitors. Synonyms: 4-(biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide; BCP32729; EX-A3829. CAS No. 1621673-53-7. Molecular formula: C27H31NO3S2. Mole weight: 481.7. | |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. KY-226 restores Akt (protein kinase B) phosphorylation and extracellular signal-regulated kinase (ERK) reduction in transient middle cerebral artery occlusion (tMCAO) damage. KY-226 protects BBB integrity by restoration of TJ proteins, an effect partly mediated by Akt/FoxO1 pathway activation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KY-226; KY 226; KY226. Product Category: Inhibitors. Appearance: Fluffy white solid powder. CAS No. 1621673-53-7. Molecular formula: C27H31NO3S2. Mole weight: 481.67. Purity: >97%. IUPACName: 4-(biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide. Canonical SMILES: O=C(NS(=O)(CCCCCC)=O)C1=CC=C(CSCC2=CC=C(C3=CC=CC=C3)C=C2)C=C1. Product ID: ACM1621673537. Alfa Chemistry ISO 9001:2015 Certified. Categories: KY 2265. |  |
| KYA1797K | KYA1797K is a potent, selective and dual inhibitor of Wnt/β-catenin (IC50= 0.75 μM) that significantly decreases reporter activities for the Wnt/β-catenin and MAPK/ERK pathways. Synonyms: potassium;3-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoate. Grades: >98%. CAS No. 1956356-56-1. Molecular formula: C17H11KN2O6S2. Mole weight: 442.51. | |
| KYL | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half life in cell culture media. It has the neuroprotective effect. Synonyms: H-Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu-OH; L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine; HY-P2264. Grades: ≥95%. CAS No. 676657-00-4. Molecular formula: C74H108N14O17. Mole weight: 1465.75. | |
| KYL | KYL. Group: Biochemicals. Grades: Purified. CAS No. 676657-00-4. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| KYL acetate | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with a Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with an IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half-life in cell culture media. It has a neuroprotective effect. Synonyms: L-Leucine, L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-, acetate; L-Lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine acetate; KYL peptide acetate; Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu acetate salt. Grades: ≥95%. Molecular formula: C74H108N14O17.C2H4O2. Mole weight: 1525.78. | |
| Kyn1-(Des-Trp1) Daptomycin | Kyn1-(Des-Trp1) Daptomycin is a derivative of Daptomycin (D193350), is a cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C71H101N17O27, Molecular Weight: 1624.66. US Biological Life Sciences. | Worldwide |
| Kynapcin-12 | It is produced by the strain of Polyozellus multiplex. It has the activity of inhibiting proline endopeptidase (PEP, EC 3.4.21.26) with IC50 of 1.25 μg/mL. Synonyms: kynapcin 12. Molecular formula: C22H18O8. Mole weight: 410.37. | |
| Kynapcin-13 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 76.80 μmol/L. It has a little inhibitory effect on other serine proteases. Synonyms: kynapcin 13. Molecular formula: C12H10O7. Mole weight: 266.20. | |
| Kynapcin-28 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 0.98 μmol/L. It has little inhibitory effect on other serine proteases. Synonyms: kynapcin 28. Molecular formula: C19H12O10. Mole weight: 400.29. | |
| Kynuramine dihydrochloride | Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36681-58-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119395B. |  |
| Kynuramine dihydrochloride | Kynuramine dihydrochloride. Group: Biochemicals. Alternative Names: 3-Amino-1-(2-aminophenyl)-1-propanone dihydrochloride. Grades: Highly Purified. CAS No. 363-36-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H12N2O·2HCl. US Biological Life Sciences. | Worldwide |
| kynurenate-7,8-dihydrodiol dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase. Other names in common use include 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase, and 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase; 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. Enzyme Commission Number: EC 1.3.1.18. CAS No. 37255-30-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1292; kynurenate-7,8-dihydrodiol dehydrogenase; EC 1.3.1.18; 37255-30-4; 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase; 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. Cat No: EXWM-1292. |  |
| Kynurenic acid | Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainic acid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Synonyms: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17. | |
| Kynurenic acid | Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. Uses: Scientific research. Group: Natural products. Alternative Names: Quinurenic acid. CAS No. 492-27-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-100806. | |
| Kynurenic Acid | A product of L-Tryptophan metabolism, possessing neuroactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; 4-Hydroxyquinaldinic Acid; Quinurenic Acid; NSC 58973. Grades: Highly Purified. CAS No. 492-27-3. Pack Sizes: 10mg, 100mg, 500mg, 1g. Molecular Formula: C10H7NO3, Melting Point: 256-258°C (dec.). US Biological Life Sciences. | Worldwide |
| Kynurenic Acid-d5 | A labeled product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid-d5; 4-Hydroxy-quinaldic Acid-d5; 2-Carboxy-4-hydroxyquinoline-d5; 4-Hydroxyquinaldic Acid-d5; 4-Hydroxyquinaldinic Acid-d5; Quinurenic Acid-d5; NSC 58973-d5. Grades: Highly Purified. CAS No. 350820-13-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Kynurenic Acid Impurity 1 | Kynurenic Acid Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18000-24-3. Molecular Formula: C10H6ClNO3. Mole Weight: 223.61. Catalog: APB18000243. |  |
| Kynurenic Acid Impurity 2 | Kynurenic Acid Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131123-76-7. Molecular Formula: C10H5Cl2NO3. Mole Weight: 258.05. Catalog: APB131123767. | |
| Kynurenic acid sodium | Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. Uses: Scientific research. Group: Natural products. CAS No. 2439-2-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107512. | |
| Kynurenic acid sodium salt | Kynurenic acid sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 2439-2-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Kynurenic acid sodium salt | Kynurenic acid sodium salt is the sodium form of kynurenic acid, which is a broad spectrum EAA antagonist. Synonyms: 4-Hydroxyquinoline-2-carboxylic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 2439-2-3. Molecular formula: C10H6NNaO3. Mole weight: 211.15. | |
| kynureninase | A pyridoxal-phosphate protein. Also acts on 3'-hydroxy-L-kynurenine and some other (3-arylcarbonyl)-alanines. Group: Enzymes. Enzyme Commission Number: EC 3.7.1.3. CAS No. 9024-78-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4732; kynureninase; EC 3.7.1.3; 9024-78-6. Cat No: EXWM-4732. | |
| kynurenine 3-monooxygenase | A flavoprotein (FAD). Group: Enzymes. Synonyms: kynurenine 3-hydroxylase; kynurenine hydroxylase; L-kynurenine-3-hydroxylase. Enzyme Commission Number: EC 1.14.13.9. CAS No. 9029-61-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0898; kynurenine 3-monooxygenase; EC 1.14.13.9; 9029-61-2; kynurenine 3-hydroxylase; kynurenine hydroxylase; L-kynurenine-3-hydroxylase. Cat No: EXWM-0898. | |
| kynurenine 7,8-hydroxylase | This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Other names in common use include kynurenic acid hydroxylase, kynurenic hydroxylase, and kynurenate 7,8-hydroxylase. This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: kynurenic acid hydroxylase; kynurenic hydroxylase; kynurenate 7,8-hydroxylase. Enzyme Commission Number: EC 1.14.99.2. CAS No. 9029-63-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1037; kynurenine 7,8-hydroxylase; EC 1.14.99.2; 9029-63-4; kynurenic acid hydroxylase; kynurenic hydroxylase; kynurenate 7,8-hydroxylase. Cat No: EXWM-1037. | |
| kynurenine-glyoxylate transaminase | Acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine. Group: Enzymes. Synonyms: kynurenine-glyoxylate aminotransferase. Enzyme Commission Number: EC 2.6.1.63. CAS No. 74506-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2904; kynurenine-glyoxylate transaminase; EC 2.6.1.63; 74506-33-5; kynurenine-glyoxylate aminotransferase. Cat No: EXWM-2904. | |
| Kynurenine Impurity 1 | Kynurenine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1022-31-7. Molecular Formula: C10H10N2O4. Mole Weight: 222.2. Catalog: APB1022317. | |
| Kynurenine Impurity 2 | Kynurenine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 75802-84-5. Molecular Formula: C10H11ClN2O3. Mole Weight: 242.66. Catalog: APB75802845. | |
| Kynurenine Impurity 3 | Kynurenine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391051-72-1. Molecular Formula: C813C2H11ClN15NO3. Mole Weight: 245.64. Catalog: APB1391051721. | |
| Kynurenine Impurity 5 | Kynurenine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153152-32-0. Molecular Formula: C10H11ClN2O3. Mole Weight: 242.66. Catalog: APB153152320. | |
| kynurenine-oxoglutarate transaminase | A pyridoxal-phosphate protein. Also acts on 3-hydroxykynurenine. The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into kynurenate by a spontaneous reaction. Group: Enzymes. Synonyms: kynurenine transaminase (cyclizing); kynurenine 2-oxoglutarate transaminase; kynurenine aminotransferase; L-kynurenine aminotransferase. Enzyme Commission Number: EC 2.6.1.7. CAS No. 9030-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2909; kynurenine-oxoglutarate transaminase; EC 2.6.1.7; 9030-38-0; kynurenine transaminase (cyclizing); kynurenine 2-oxoglutarate transaminase; kynurenine aminotransferase; L-kynurenine aminotransferase. Cat No: EXWM-2909. | |
| Kyotorphin | Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients [1]. Uses: Scientific research. Group: Peptides. CAS No. 70904-56-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122381. | |
| Kyotorphin | Kyotorphin is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It is synthesized at nerve terminals and found in the brain and cerebrospinal fluid (CSF). People with persistent pain and alzheimer's disease have lower levels of cerebrospinal fluid. Uses: Analgesics. Synonyms: H-Tyr-Arg-OH; L-tyrosyl-L-arginine; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-5-guanidinopentanoic acid; Arginine, N2-tyrosyl-; L-Arginine, N2-L-tyrosyl-. Grades: ≥95%. CAS No. 70904-56-2. Molecular formula: C15H23N5O4. Mole weight: 337.37. | |
| Kyotorphin | Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TYR-ARG-OH;KYOTORPHIN;KYOTORPHIN, BOVINE;TYR-ARG;YR;kyotorphin acetate;(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid;L-Tyr-L-Arg-OH. Product Category: Inhibitors. CAS No. 70904-56-2. Molecular formula: C15H23N5O4. Mole weight: 337.37. Purity: 0.96. IUPACName: (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid. Canonical SMILES: C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)N)O. Density: 1.43 g/cm³. Product ID: ACM70904562. Alfa Chemistry ISO 9001:2015 Certified. | |
| Kyotorphin acetate | Kyotorphin acetate is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It can be used as a biomarker of Alzheimer's disease. Synonyms: H-Tyr-Arg-OH.CH3CO2H; YR.CH3CO2H; L-tyrosyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 212185-19-8. Molecular formula: C15H23N5O4.C2H4O2. Mole weight: 397.43. | |
| Kyowanol M 25265-77-4 | Kyowanol M - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| KYP-2047 | KYP-2047 is a selective Prolyl oligopeptidase inhibitor. And it is also known as prolyl endopeptidase. KYP-2047 can reduce α-synuclein protein levels and aggregate in cellular and animal models of Parkinson's disease. KYP-2047 can clear the α-synuclein aggregates induced by oxidative stress in the neuronal cells. Uses: Parkinson's disease. Synonyms: KYP-2047; KYP2047; KYP 2047. (2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile. Grades: 95%. CAS No. 796874-99-2. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
| Kzo9 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. ↑GATC CTAG&darr. Activity: 1000-5000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Kurthia zopfii 9. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1127RE. | |
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