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| Product | Description | |
|---|---|---|
| Kuwanol C | Flavonoids. CAS No. 123702-94-3. Molecular formula: C25H26O6. Mole weight: 422.5. Appearance: Powder. Purity: 0.98. IUPACName: (8S)-8-(2,4-dihydroxyphenyl)-5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-7,8-dihydropyrano[3,2-g]chromen-6-one. Canonical SMILES: CC (=CCCC1 (C=CC2=C (C3=C (C=C2O1)OC (CC3=O)C4=C (C=C (C=C4)O)O)O)C)C. Catalog: ACM123702943. |  |
| Kuwanon A | Kuwanon A. Group: Biochemicals. CAS No. 62949-77-3. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Kuwanon A | Kuwanon A, a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.), inhibits nitric oxide production (IC50 = 10.5 μM). Synonyms: 5,7-dihydroxy-2-(5-hydroxy-2,2-dimethylchromen-8-yl)-3-(3-methylbut-2-enyl)chromen-4-one. CAS No. 62949-77-3. Molecular formula: C25H24O6. Mole weight: 420.45. |  |
| Kuwanon E | Kuwanon E. Group: Biochemicals. CAS No. 68401-05-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Kuwanon G | Kuwanon G is a flavonoid isolated from Morus alba, acts as a bombesin receptor antagonist, with potential antimicrobial activity. Group: Inhibitors. Alternative Names: kuwanon G;8-[(1S)-6α-(2,4-Dihydroxybenzoyl)-5β-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1β-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;Albanin F;Moracenin B;NSC 356888. CAS No. 75629-19-5. Molecular formula: C40H36O11. Mole weight: 692.71. Appearance: Solid. Purity: 0.95. Canonical SMILES: O=C1C (C/C=C (C)\C)=C (C2=CC=C (O)C=C2O)OC3=C ([C@H]4C=C (C)C[C@@H] (C5=CC=C (O)C=C5O)[C@@H]4C (C6=CC=C (O)C=C6O)=O)C (O)=CC (O)=C13. Catalog: ACM75629195. | |
| Kuwanon G | Kuwanon G. Group: Biochemicals. Grades: Highly Purified. CAS No. 75629-19-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C40H36O11. US Biological Life Sciences. | Worldwide |
| Kuwanon H | Kuwanon H. Group: Biochemicals. CAS No. 76472-87-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Kuwanon K | Kuwanon K is a natural product that can be isolated from Morus Lhou [1]. Uses: Scientific research. Group: Natural products. CAS No. 88524-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11463. |  |
| Kv1.3 Channel blocker 42 | Kv1.3 Channel blocker 42 is a selective potassium channel blocker of Kv1.3 current (IC50 < 50 nM). Kv1.3 channel blocker is promisingly used for the treatment of obesity and insulin resistance. Synonyms: Kv1.3 Channel blocker 42; 2108780-57-8; E98959; 1-(7-(3-(4-fluorophenyl)butoxy)-2,4-dimethyl-6-(2-(piperidin-1-yl)ethoxy)benzo[d]oxazol-5-yl)ethanone Hydrochloride. Grades: 99%. CAS No. 2108780-57-8. Molecular formula: C28H35FN2O4.HCl. Mole weight: 519.05. | |
| Kv1.3 Control Antigen (Kcna3, Charybdotoxin- sensitive Voltage-dependent Potassium Channel, HLK3) | Kv1.3 Control Antigen (Kcna3, Charybdotoxin- sensitive Voltage-dependent Potassium Channel, HLK3). Group: Molecular Biology. Grades: Purified. Pack Sizes: 120ug. US Biological Life Sciences. | Worldwide |
| Kv2.1-IN-1 | Kv2.1-IN-1 (compound 80) is a potent inhibitor of Kv2.1, with the IC 50 value of 0.07 μM, selectivity >130 fold over other K + , Na + , and Ca 2+ ion channels [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2252448-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161104. | |
| Kw-2449 | KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively. Group: Inhibitors. CAS No. 1000669-72-6. Molecular formula: C20H20N4O. Mole weight: 332.4. Purity: >99%. Catalog: ACM1000669726. | |
| KW-2449 | KW-2449 is a novel multikinase inhibitor, which suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation. Recent research showed that HDACIs increase KW-2449 lethality in Bcr/Abl(+) cells in association with inhibition of Bcr/Abl, generation of ROS, and induction of DNA damage. This strategy preferentially targets primary Bcr/Abl(+) hematopoietic cells and exhibits enhanced in vivo activity. Combining KW-2449 with HDACIs warrants attention in IM-resistant Bcr/Abl(+) leukemias. Synonyms: KW2449; KW-2449; KW 2449. CAS No. 1000669-72-6. Molecular formula: C20H20N4O. Mole weight: 332.407. | |
| KW-2450 Tosylate salt | KW-2450 is insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) antagonist. KW-2450 can selectively bind to and inhibit the activities of IGF-1R and IR and this may lead to the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. In Apr 2013, Phase-I/II for Breast cancer and Phase-I for Solid tumours were discontinued in USA. Uses: Breast cancer; solid tumours. Synonyms: KW-2450 Tosylate salt; KW 2450 Tosylate salt; KW2450 Tosylate salt; (E)-N-(2-(2-(1H-indazol-3-yl)vinyl)-5-((4-(2-hydroxyacetyl)piperazin-1-yl)methyl)phenyl)-3-methylthiophene-2-carboxamide 4-methylbenzenesulfonate; 904899-25-8 (free base). Grades: 98%. CAS No. 1360433-93-7. Molecular formula: C35H37N5O6S2. Mole weight: 687.83. | |
| KW-2478 | KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW-2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells. Hsp90 is a molecular chaperone that plays a key role in the conformational maturation of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation or immune responses. Synonyms: 2-(2-ethyl-3,5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N,N-bis(2-methoxyethyl)acetamide; KW 2478; KW2478; QY50S617NM; 2-[2-ethyl-3,5-dihydroxy-6-[3-methoxy-4-(2-morpholin-4-ylethoxy)benzoyl]phenyl]-N,N-bis(2-methoxyethyl)acetamide; 819812-04-9 (free base); 2-[2-ethyl-6-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]carbonyl-3,5-bis(oxidanyl)phenyl]-~{N},~{N}-bis(2-methoxyethyl)ethanamide. Grades: >98%. CAS No. 819812-04-9. Molecular formula: C30H42N2O9. Mole weight: 574.66. | |
| KW-2478 | KW-2478 is an inhibitor of Hsp90α , with an IC 50 of 3.8 nM, and has antitumor activity against various human hematological tumor cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 819812-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13468. | |
| KW 3902 | KW 3902. Group: Biochemicals. Grades: Purified. CAS No. 136199-02-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KW-3902 | KW-3902 is a selective adenosine A1 receptor antagonist under the development of Kyowa Hakko and Merck & Co. It displays 890-fold selectivity for rat A1 receptors over A2A receptors. (Ki value for adenosine A1 is 0.19 nM; 170 nM for adenosine A2A ). KW-3902 exhibits diuretic and renal protective effects in rats. Clinical trials for the treatment of Acute heart failure, Cognition disorders and Hypertension was discontinued. Uses: Acute heart failure; cognition disorders; hypertension. Synonyms: 1,3-dipropyl-8-(3-noradamantyl)xanthine, 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione, KW-3902; KW 3902; KW3902; Rolofylline. Grades: 98%. CAS No. 136199-02-5. Molecular formula: C20H28N4O2. Mole weight: 356.46. | |
| KW-8232 | KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 217813-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100304A. | |
| KW-8232 free base | KW-8232 free base, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170365-25-0. Pack Sizes: 1 mg. Product ID: HY-100304. | |
| KWG 1342 | KWG 1342. Group: Biochemicals. Alternative Names: 4-(4-Chlorophenoxy)-2,2-dimethyl-4-(1H-1,2,4-triazol-1-yl)-1,3-butanediol. Grades: Highly Purified. CAS No. 72699-18-4. Pack Sizes: 2.5mg. Molecular Formula: C14H18ClN3O3, Molecular Weight: 311.76. US Biological Life Sciences. | Worldwide |
| KWG 1342 Sulfate Sodium Salt | KWG 1342 Sulfate Sodium Salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H17ClN3NaO6S, Molecular Weight: 413.81. US Biological Life Sciences. | Worldwide |
| KX1-004 | KX1-004 is an Src-protein tyrosine kinase inhibitor to reduce cisplatin ototoxicity while preserving its antitumor effect. KX1-004 has been used to protect the cochlea from hazardous noise. Synonyms: KX1-004; KX 1-004; KX1 004. Grades: 0.98. CAS No. 518058-84-9. Molecular formula: C16H13FN2O2. Mole weight: 284.29. | |
| KX1-141 | KX1-141 is an Src-protein tyrosine kinase inhibitor, which may reduce cisplatin ototoxicity while preserving its antitumor effect. Synonyms: KX-1-141; KX 1-141; 1H-Indole-2-carboxamide, 7-(3-ethoxyphenyl)-5-fluoro-N-[(3-fluorophenyl)methyl]-. Grades: 98%. CAS No. 1000706-00-2. Molecular formula: C24H20F2N2O2. Mole weight: 406.42. | |
| KX2-391 | KX2-391 is an orally bioavailable small molecule Src kinase inhibitor with potential antineoplastic activity. Unlike other Src kinase inhibitors which bind to the ATP-binding site, Src kinase inhibitor KX2-391 specifically binds to the peptide substrate binding site of Src kinase; inhibition of kinase activity may result in the inhibition of primary tumor growth and the suppression of metastasis. Src tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. Uses: Enzyme inhibitors. Synonyms: KX01, KX-01, KX 01, KX2-391; KX-2-391; KX 2-391; KX2391; KX-2391; KX 2391; Tirbanibulin. CAS No. 897016-82-9. Molecular formula: C26H29N3O3. Mole weight: 431.53. | |
| KX2-391 dihydrochloride | KX2-391 2Hcl is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Synonyms: KX2-391 dihydrochloride; 1038395-65-1; KX2-391 (dihydrochloride); Tirbanibulin (dihydrochloride); N-benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]acetamide;dihydrochloride. Grades: >98%. CAS No. 1038395-65-1. Molecular formula: C26H31Cl2N3O3. Mole weight: 504.45. | |
| KY02111 | KY02111 is a canonical WNT signaling (β-catenin) inhibitor which promotes differentiation of hPSCs to cardiomyocytes. KY02111 can be used for the research of human cardiomyocyte regeneration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1118807-13-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13815. | |
| KY02111 | KY02111. Group: Biochemicals. Alternative Names: KY 02111, KY-02111, CHEMBL3186128, HY-13815, S-7828. Grades: Highly Purified. CAS No. 1118807-13-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C18 H17 ClN 2O3, Molecular Weight: 376.9. US Biological Life Sciences. | Worldwide |
| KY02111 | KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling. Synonyms: N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide. Grades: >98%. CAS No. 1118807-13-8. Molecular formula: C18H17ClN2O3S. Mole weight: 376.86. | |
| KY 02111 | KY 02111. Group: Biochemicals. Grades: Purified. CAS No. 1118807-13-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KY 05009 | KY 05009 is an inhibitor of Traf2- and Nck-Interacting Kinase (TNIK; Ki value 100 nM in ATP competitive assay) that attenuates TGF-β1-mediated Wnt and Smad signaling and epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma A549 cells. In addition, KY05009 inhibits TGF-β1-induced phosphorylation of JNK1/2, FAK, Src, and paxillin. Synonyms: KY 05009; KY05009; KY-05009; 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide; 2-anilino-5-[(4-methylbenzoyl)amino]-1,3-thiazole-4-carboxamide. Grades: 99%. CAS No. 1228280-29-2. Molecular formula: C18H16N4O2S. Mole weight: 352.41. | |
| KY-1044 | KY-1044 is a novel anti-inducible co-stimulator molecule (ICOS) subclass G1 kappa monoclonal antibody developed for the treatment of cancer. KY-1044 has a dual mechanism of action: stimulating immune cells which are fighting the tumor, while also killing a type of cell known as T regulatory cells (Tregs). Uses: Potential cancer therapy. Synonyms: KY-1044; KY1044; KY1044. | |
| KY1220 | KY1220 is a novel inhibitor of the Wnt/ß-catenin pathway, destabilizing both β-catenin and Ras via targeting the Wnt/β-catenin pathway (IC50= 2.1 μM in HEK293 reporter cells). Synonyms: KY1220; KY-1220; KY 1220; (5Z)-5-[[1-(4-nitrophenyl)pyrrol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one. CAS No. 292168-79-7. Molecular formula: C14H10N4O3S. Mole weight: 314.32. | |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. It significantly reduced plasma glucose, triglyceride, and A1c levels without weight gain in db/db mice. Uses: Enzyme inhibitors. Synonyms: 4-(biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide; BCP32729; EX-A3829. CAS No. 1621673-53-7. Molecular formula: C27H31NO3S2. Mole weight: 481.7. | |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. KY-226 restores Akt (protein kinase B) phosphorylation and extracellular signal-regulated kinase (ERK) reduction in transient middle cerebral artery occlusion (tMCAO) damage. KY-226 protects BBB integrity by restoration of TJ proteins, an effect partly mediated by Akt/FoxO1 pathway activation. Group: Inhibitors. Alternative Names: KY-226; KY 226; KY226. CAS No. 1621673-53-7. Molecular formula: C27H31NO3S2. Mole weight: 481.67. Appearance: Fluffy white solid powder. Purity: >97%. IUPACName: 4-(biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide. Canonical SMILES: O=C (NS (=O) (CCCCCC)=O)C1=CC=C (CSCC2=CC=C (C3=CC=CC=C3)C=C2)C=C1. Catalog: ACM1621673537. | |
| KYA1797K | KYA1797K is a potent, selective and dual inhibitor of Wnt/β-catenin (IC50= 0.75 μM) that significantly decreases reporter activities for the Wnt/β-catenin and MAPK/ERK pathways. Synonyms: potassium;3-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoate. Grades: >98%. CAS No. 1956356-56-1. Molecular formula: C17H11KN2O6S2. Mole weight: 442.51. | |
| KYL | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half life in cell culture media. It has the neuroprotective effect. Synonyms: H-Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu-OH; L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine; HY-P2264. Grades: ≥95%. CAS No. 676657-00-4. Molecular formula: C74H108N14O17. Mole weight: 1465.75. | |
| KYL | KYL. Group: Biochemicals. Grades: Purified. CAS No. 676657-00-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KYL acetate | KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with a Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with an IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half-life in cell culture media. It has a neuroprotective effect. Synonyms: L-Leucine, L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-, acetate; L-Lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine acetate; KYL peptide acetate; Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu acetate salt. Grades: ≥95%. Molecular formula: C74H108N14O17.C2H4O2. Mole weight: 1525.78. | |
| Kyn1-(Des-Trp1) Daptomycin | Kyn1-(Des-Trp1) Daptomycin is a derivative of Daptomycin (D193350), is a cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C71H101N17O27, Molecular Weight: 1624.66. US Biological Life Sciences. | Worldwide |
| Kynapcin-12 | It is produced by the strain of Polyozellus multiplex. It has the activity of inhibiting proline endopeptidase (PEP, EC 3.4.21.26) with IC50 of 1.25 μg/mL. Synonyms: kynapcin 12. Molecular formula: C22H18O8. Mole weight: 410.37. | |
| Kynapcin-13 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 76.80 μmol/L. It has a little inhibitory effect on other serine proteases. Synonyms: kynapcin 13. Molecular formula: C12H10O7. Mole weight: 266.20. | |
| Kynapcin-28 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 0.98 μmol/L. It has little inhibitory effect on other serine proteases. Synonyms: kynapcin 28. Molecular formula: C19H12O10. Mole weight: 400.29. | |
| Kynuramine dihydrochloride | Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36681-58-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119395B. | |
| Kynuramine dihydrochloride | Kynuramine dihydrochloride. Group: Biochemicals. Alternative Names: 3-Amino-1-(2-aminophenyl)-1-propanone dihydrochloride. Grades: Highly Purified. CAS No. 363-36-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H12N2O·2HCl. US Biological Life Sciences. | Worldwide |
| kynurenate-7,8-dihydrodiol dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase. Other names in common use include 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase, and 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase; 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. Enzyme Commission Number: EC 1.3.1.18. CAS No. 37255-30-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1292; kynurenate-7,8-dihydrodiol dehydrogenase; EC 1.3.1.18; 37255-30-4; 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase; 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. Cat No: EXWM-1292. |  |
| Kynurenic acid | Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. Uses: Scientific research. Group: Natural products. Alternative Names: Quinurenic acid. CAS No. 492-27-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-100806. | |
| Kynurenic acid | Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainic acid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Synonyms: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17. | |
| Kynurenic Acid | A product of L-Tryptophan metabolism, possessing neuroactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; 4-Hydroxyquinaldinic Acid; Quinurenic Acid; NSC 58973. Grades: Highly Purified. CAS No. 492-27-3. Pack Sizes: 10mg, 100mg, 500mg, 1g. Molecular Formula: C10H7NO3, Melting Point: 256-258°C (dec.). US Biological Life Sciences. | Worldwide |
| Kynurenic Acid-d5 | A labeled product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid-d5; 4-Hydroxy-quinaldic Acid-d5; 2-Carboxy-4-hydroxyquinoline-d5; 4-Hydroxyquinaldic Acid-d5; 4-Hydroxyquinaldinic Acid-d5; Quinurenic Acid-d5; NSC 58973-d5. Grades: Highly Purified. CAS No. 350820-13-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Kynurenic Acid Impurity 1 | Kynurenic Acid Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18000-24-3. Molecular Formula: C10H6ClNO3. Mole Weight: 223.61. Catalog: APB18000243. |  |
| Kynurenic Acid Impurity 2 | Kynurenic Acid Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131123-76-7. Molecular Formula: C10H5Cl2NO3. Mole Weight: 258.05. Catalog: APB131123767. | |
| Kynurenic acid sodium | Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. Uses: Scientific research. Group: Natural products. CAS No. 2439-2-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107512. | |
| Kynurenic acid sodium salt | Kynurenic acid sodium salt is the sodium form of kynurenic acid, which is a broad spectrum EAA antagonist. Synonyms: 4-Hydroxyquinoline-2-carboxylic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 2439-2-3. Molecular formula: C10H6NNaO3. Mole weight: 211.15. | |
| Kynurenic acid sodium salt | Kynurenic acid sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 2439-2-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| kynureninase | A pyridoxal-phosphate protein. Also acts on 3'-hydroxy-L-kynurenine and some other (3-arylcarbonyl)-alanines. Group: Enzymes. Enzyme Commission Number: EC 3.7.1.3. CAS No. 9024-78-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4732; kynureninase; EC 3.7.1.3; 9024-78-6. Cat No: EXWM-4732. | |
| kynurenine 3-monooxygenase | A flavoprotein (FAD). Group: Enzymes. Synonyms: kynurenine 3-hydroxylase; kynurenine hydroxylase; L-kynurenine-3-hydroxylase. Enzyme Commission Number: EC 1.14.13.9. CAS No. 9029-61-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0898; kynurenine 3-monooxygenase; EC 1.14.13.9; 9029-61-2; kynurenine 3-hydroxylase; kynurenine hydroxylase; L-kynurenine-3-hydroxylase. Cat No: EXWM-0898. | |
| kynurenine 7,8-hydroxylase | This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Other names in common use include kynurenic acid hydroxylase, kynurenic hydroxylase, and kynurenate 7,8-hydroxylase. This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: kynurenic acid hydroxylase; kynurenic hydroxylase; kynurenate 7,8-hydroxylase. Enzyme Commission Number: EC 1.14.99.2. CAS No. 9029-63-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1037; kynurenine 7,8-hydroxylase; EC 1.14.99.2; 9029-63-4; kynurenic acid hydroxylase; kynurenic hydroxylase; kynurenate 7,8-hydroxylase. Cat No: EXWM-1037. | |
| kynurenine-glyoxylate transaminase | Acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine. Group: Enzymes. Synonyms: kynurenine-glyoxylate aminotransferase. Enzyme Commission Number: EC 2.6.1.63. CAS No. 74506-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2904; kynurenine-glyoxylate transaminase; EC 2.6.1.63; 74506-33-5; kynurenine-glyoxylate aminotransferase. Cat No: EXWM-2904. | |
| Kynurenine Impurity 1 | Kynurenine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1022-31-7. Molecular Formula: C10H10N2O4. Mole Weight: 222.2. Catalog: APB1022317. | |
| Kynurenine Impurity 2 | Kynurenine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 75802-84-5. Molecular Formula: C10H11ClN2O3. Mole Weight: 242.66. Catalog: APB75802845. | |
| Kynurenine Impurity 3 | Kynurenine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391051-72-1. Molecular Formula: C813C2H11ClN15NO3. Mole Weight: 245.64. Catalog: APB1391051721. | |
| Kynurenine Impurity 5 | Kynurenine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153152-32-0. Molecular Formula: C10H11ClN2O3. Mole Weight: 242.66. Catalog: APB153152320. | |
| kynurenine-oxoglutarate transaminase | A pyridoxal-phosphate protein. Also acts on 3-hydroxykynurenine. The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into kynurenate by a spontaneous reaction. Group: Enzymes. Synonyms: kynurenine transaminase (cyclizing); kynurenine 2-oxoglutarate transaminase; kynurenine aminotransferase; L-kynurenine aminotransferase. Enzyme Commission Number: EC 2.6.1.7. CAS No. 9030-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2909; kynurenine-oxoglutarate transaminase; EC 2.6.1.7; 9030-38-0; kynurenine transaminase (cyclizing); kynurenine 2-oxoglutarate transaminase; kynurenine aminotransferase; L-kynurenine aminotransferase. Cat No: EXWM-2909. | |
| Kyotorphin | Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients [1]. Uses: Scientific research. Group: Peptides. CAS No. 70904-56-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122381. | |
| Kyotorphin | Kyotorphin is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It is synthesized at nerve terminals and found in the brain and cerebrospinal fluid (CSF). People with persistent pain and alzheimer's disease have lower levels of cerebrospinal fluid. Uses: Analgesics. Synonyms: H-Tyr-Arg-OH; L-tyrosyl-L-arginine; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-5-guanidinopentanoic acid; Arginine, N2-tyrosyl-; L-Arginine, N2-L-tyrosyl-. Grades: ≥95%. CAS No. 70904-56-2. Molecular formula: C15H23N5O4. Mole weight: 337.37. | |
| Kyotorphin | Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients. Group: Inhibitors. Alternative Names: H-TYR-ARG-OH;KYOTORPHIN;KYOTORPHIN, BOVINE;TYR-ARG;YR;kyotorphin acetate; (2S)-2-[[ (2S)-2-amino-3- (4-hydroxyphenyl)propanoyl]amino]-5- (diaminomethylideneamino)pentanoic acid;L-Tyr-L-Arg-OH. CAS No. 70904-56-2. Molecular formula: C15H23N5O4. Mole weight: 337.37. Purity: 0.96. IUPACName: (2S)-2-[[ (2S)-2-amino-3- (4-hydroxyphenyl)propanoyl]amino]-5- (diaminomethylideneamino)pentanoic acid. Canonical SMILES: C1=CC (=CC=C1CC (C (=O)NC (CCCN=C (N)N)C (=O)O)N)O. Density: 1.43 g/cm³. Catalog: ACM70904562. | |
| Kyotorphin acetate | Kyotorphin acetate is an endogenous neuroactive dipeptide with analgesic, neuroprotective and neuroregulatory properties. Kyotorphin has anti-inflammatory and antibacterial activities. It can be used as a biomarker of Alzheimer's disease. Synonyms: H-Tyr-Arg-OH.CH3CO2H; YR.CH3CO2H; L-tyrosyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 212185-19-8. Molecular formula: C15H23N5O4.C2H4O2. Mole weight: 397.43. | |
| Kyowanol M 25265-77-4 | Kyowanol M - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| KYP-2047 | KYP-2047 is a selective Prolyl oligopeptidase inhibitor. And it is also known as prolyl endopeptidase. KYP-2047 can reduce α-synuclein protein levels and aggregate in cellular and animal models of Parkinson's disease. KYP-2047 can clear the α-synuclein aggregates induced by oxidative stress in the neuronal cells. Uses: Parkinson's disease. Synonyms: KYP-2047; KYP2047; KYP 2047. (2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile. Grades: 95%. CAS No. 796874-99-2. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
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