A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
2.5lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 90005253-2.5lt. See USA prepack pricing.
Karl-Fischer Reagent (Uniquant 5)
1lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 90005253-1lt. See USA prepack pricing.
Karl-Fischer working medium K solvent
1lt Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators, Water Analysis. Formula: N/A. Prepack ID 34496486-1lt. See USA prepack pricing.
Kartogenin (KGN) is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN. CAS No. 4727-31-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16268.
Kartogenin
Kartogenin. Group: Biochemicals. Grades: Purified. CAS No. 4727-31-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A cell-permeable biphenyl carbamoyl benzoate compound that potently induces the differentiation of human mesenchymal stem cells (hMSCs) into chondrocytes (EC500nM). Reversibly binds to the FC-1 fragment of filamin A and disrupts its association with CBFB leading to nuclear localization of CBFB and binding to runt-related transcription factor (RUNX) to regulate chondrogenesis. Also reported to inhibit cytokine-induced release of nitric oxide (NO) and glycosaminoglycan (GAG). Exhibits chondroprotective properties and promotes cartilage repair in murine osteoarthritis models. Shown to up-regulate the levels of TIMP1, collagen, and aggrecan thereby blocking further matrix breaown without affecting the activities of MMP-3, MMP-13, and aggrecanase in primary chondrocytes or hMSCs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??NO?, Molecular Weight: 317.3. US Biological Life Sciences.
Worldwide
Kartogenin sodium
Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN sodium. CAS No. 1401168-39-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-16268A.
Kasseptin 1Ma
Kasseptin 1Ma is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Leu-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Val-Thr-Asn-Ala-Leu-NH2. Molecular formula: C92H151N25O23. Mole weight: 1975.37.
Kasseptin 1Mb
Kasseptin 1Mb is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Phe-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Ser-Ala-Ile-Lys-Asn-Ala-Leu-NH2. Molecular formula: C97H155N25O22. Mole weight: 2023.46.
Kasseptin 1Mc
Kasseptin 1Mc is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Val-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Ser-Ala-Ile-Lys-Asn-Ala-Leu-NH2. Molecular formula: C93H155N25O22. Mole weight: 1975.42.
Kasseptin 1Md
Kasseptin 1Md is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ile-Ile-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Ile-Lys-Asn-Thr-Phe-NH2. Grade: 95.7%. Molecular formula: C96H160N26O23. Mole weight: 2046.50.
Kassinatuerin-1
Kassinatuerin-1 is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: H-Gly-Phe-Met-Lys-Tyr-Ile-Gly-Pro-Leu-Ile-Pro-His-Ala-Val-Lys-Ala-Ile-Ser-Asp-Leu-Ile-NH2. Grade: 96.0%. Molecular formula: C109H176N26O25S. Mole weight: 2282.82.
Kassinatuerin-2
Kassinatuerin-2 is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: H-Phe-Ile-Gln-Tyr-Leu-Ala-Pro-Leu-Ile-Pro-His-Ala-Val-Lys-Ala-Ile-Ser-Asp-Leu-Ile-NH2. Grade: 95.8%. Molecular formula: C108H173N25O25. Mole weight: 2221.72.
Kassinatuerin-2Md
Kassinatuerin-2Md is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria. Synonyms: Phe-Ile-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Ile-Lys-Asn-Thr-Phe. Grade: 96.0%.
Kassinin
Kassinin, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signalling and shows selectivity for NK2 over NK1 in mammals. Uses: Neurotransmitter agents. Synonyms: CID45749; Kassinin. CAS No. 63968-82-1. Molecular formula: C59H95N15O18S. Mole weight: 1334.54.
Kassinin acetate
Kassinin acetate, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signaling and shows selectivity for NK2 over NK1 in mammals. Synonyms: H-Asp-Val-Pro-Lys-Ser-Asp-Gln-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-α-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-methioninamide acetate. Grade: ≥95%. Molecular formula: C61H99N15O20S. Mole weight: 1394.59.
Kassorin-S
Kassorin-S is an antibacterial peptide isolated from Kassina senegalensis. Kassorin-S has antibacterial activity against Staphylococcus aureus. Synonyms: Phe-Leu-Gly-Gly-Ile-Leu-Asn-Thr-Ile-Thr-Gly-Leu-Leu-NH2. Molecular formula: C63H107N15O16. Mole weight: 1330.64.
Kasstasin
Kasstasin is an antibacterial peptide isolated from Kassina maculata (spotted running frog). Synonyms: Ile-Lys-Glu-Leu-Leu-Pro-His-Leu-Ser-Gly-Ile-Ile-Asp-Ser-Val-Ala-Asn-Ala-Ile-Lys.
Kastle-Meyer Reagent, in dropper bottle, Laboratory Grade, 30 mL
Notes: 2% phenolphthalein in 20% potassium hydroxide solution. Storage Code: White; corrosive. Uses: use with hydrogen peroxide for presumptive blood tests. Grades: chem-grade laboratory. Product ID: 871300. -- SOLD FOR EDUCATIONAL USE ONLY --
Kasugamycin
It is produced by the strain of Str. sugaensis M-388 (ATCC-15714, -15715). Kasugamycin has antibacterial properties against certain bacteria and fungi. Synonyms: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-; 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol; Kasu B; Kasumin 2L; Kasumin 4WP; Kasumin L; KSM; NSC 100858. Grade: ≥95%. CAS No. 6980-18-3. Molecular formula: C14H25N3O9. Mole weight: 379.36.
Kasugamycin HCl
Kasugamycin HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 19408-46-9. Pack Sizes: 500g, 1kg, 2kg. US Biological Life Sciences.
Worldwide
Kasugamycin hydrochloride
Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ksg hydrochloride. CAS No. 19408-46-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-B1864A.
Kasugamycin hydrochloride
Kasugamycin hydrochloride is an aminoglycoside antibiotic produced by Streptomyces. It is a broad spectrum antifungal used against yeast and pathogenic fungi such as M. Grisea. Synonyms: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, hydrochloride (1:1); D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, monohydrochloride; Kasugamycin, monohydrochloride; Kasumin. Grade: ≥73.5%. CAS No. 19408-46-9. Molecular formula: C14H26ClN3O9. Mole weight: 415.82.
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ksg hydrochloride hydrate. CAS No. 200132-83-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1864B.
Kasugamycin sulfate)
Kasugamycin sulfate). Uses: Designed for use in research and industrial production. Additional or Alternative Names: kasugamycin hemisulfate. Product Category: Heterocyclic Organic Compound. CAS No. 78822-08-9. Molecular formula: 2C14H25N3O9.H2O4S. Mole weight: 856.805. Product ID: ACM78822089. Alfa Chemistry ISO 9001:2015 Certified.
KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 ?M (KAT8), 221 ?M (KAT2B), 106 ?M (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 605-62-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W015239.
Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PDN 21. CAS No. 85916-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0149.
Katacalcin
Katacalcin is a second potent plasma calcium-lowering peptide that may be a useful marker for the detection of medullary thyroid carcinoma. Uses: Calcium-regulating hormones and agents. Synonyms: PDN 21; H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH; L-alpha-aspartyl-L-methionyl-L-seryl-L-seryl-L-alpha-aspartyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-prolyl-L-histidyl-L-valyl-L-seryl-L-methionyl-L-prolyl-L-glutaminyl-L-asparagyl-L-alanyl-L-asparagine; Calcitonin C-Terminal Flanking Peptide (human). Grade: ≥95%. CAS No. 85916-47-8. Molecular formula: C97H154N34O36S2. Mole weight: 2436.59.
Katacalcin TFA
Katacalcin TFA is a second potent plasma calcium-lowering peptide that may be a useful marker for the detection of medullary thyroid carcinoma. Synonyms: PDN 21 (TFA); Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn.TFA; L-alpha-aspartyl-L-methionyl-L-seryl-L-seryl-L-alpha-aspartyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-prolyl-L-histidyl-L-valyl-L-seryl-L-methionyl-L-prolyl-L-glutaminyl-L-asparagyl-L-alanyl-L-asparagine Trifluoroacetate; Calcitonin C-Terminal Flanking Peptide (human) Trifluoroacetate; Katacalcin Trifluoroacetate. Grade: >98%. Molecular formula: C97H154N34O36S2.C2HF3O2. Mole weight: 2550.62.
Katanosin A
Katanosin A is a peptide antibiotic originally isolated from Cytophaga sp. PBJ-5356. It has anti-gram-positive bacterial effect. Synonyms: L-Serine, N-[threo-3-hydroxy-N2-[N-[N-[N-[N2-[N-[threo-3-hydroxy-N-[threo-b-hydroxy-N-(N-D-leucyl-L-leucyl)-L-phenylalanyl]-L-leucyl]-L-leucyl]-D-arginyl]-L-valyl]-L-allothreonyl]glycyl]-L-asparaginyl]-,b1-lactone. CAS No. 116103-86-7. Molecular formula: C57H95N15O17. Mole weight: 1262.45.
Kaurenoic acid is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, and also exhibits cytotoxic and embryotoxic effects. It acts through inhibition of iNOS and COX-2 expression. Uses: Anti-inflammatory. Synonyms: (-)-Kaur-16-en-18-oic acid; Cunabic acid; Kaurane-16-ene-18-oic acid; ent-Kaur-16(17)-en-19-oic acid; ent-Kaur-16-en-19-oic acid; NSC 339145; Kaur-16-en-18-oic acid,(4a)-. Grade: >98%. CAS No. 6730-83-2. Molecular formula: C20H30O2. Mole weight: 302.46.
Kaurenoic acid
Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 6730-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N1469.
Kauri gum
Kauri gum. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KAURI GUM;gum kauri;Kauri GuM (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 77465-88-4. Mole weight: 0. Product ID: ACM77465884. Alfa Chemistry ISO 9001:2015 Certified.
Kava Extract
Kava extract is prepared from the root of medicina plant kava, native to the Pacific islands. Kava extract powder is used as a herbal remedy in the form of an extract called seanol, a polyphenolic extract. Kava extract is used frequently in herbal medicine to treat anxiety and insomnia. Kava extract is commonly prescribed by herbalists and alternative medicine practitioners for all types of anxiety disorders. Group: Others. Kava Extract; Piper Methysticum. Cat No: EXTC-051.
Kavain
Kavain. Group: Biochemicals. Grades: Plant Grade. CAS No. 500-64-1. Pack Sizes: 10mg. Molecular Formula: C14H14O3, Molecular Weight: 230.26. US Biological Life Sciences.
Worldwide
Kavain
Kavain is a class of kavalactone isolated from Piper methysticum , which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor [1]. Uses: Scientific research. Group: Natural products. CAS No. 3155-48-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N2096.
analytical standard, 65% (NMR), solid. Group: Drugs of abuse.
Kazinol B
Kazinol B is a natural flavonoid found in the barks of Broussonetia papyrife. It has inhibition of nitric oxide production on LPS-activated macrophages and has inhibiion of SOCE. Synonyms: (2S)-2',2'-dimethyl-7'-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,2'H-2,6'-bichrom ene-7,8'-diol. Grade: >98%. CAS No. 99624-27-8. Molecular formula: C25H28O4. Mole weight: 392.5.
Kazinol U
Kazinol U is one estrogenic found in Broussonetia kazinoki. Kazinoki may be useful in the treatment of menopausal symptoms and may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes. Synonyms: 4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol. Grade: >96%. CAS No. 1238116-48-7. Molecular formula: C20H22O4. Mole weight: 326.39.
Kazusamycin a
Kazusamycin a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Kazusamycin, Kazusamycin A, Antibiotic CL1957B, Antibiotic 81-484, AIDS058215, AIDS-058215, PD 114721, CID6436292, 94664-05-8 (DELETED), LS-185045, 2,10,12,16,18-Nonadecapentaenoic acid, Kazusamycin A, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, 92090-94-3, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,10E,12E,16Z,18E)-, 94664-05-8. Product Category: Heterocyclic Organic Compound. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73. Purity: 0.96. IUPACName: (2E,10E,12E,16Z,18E)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid. Density: 1.109±0.06 g/cm³ (20 °C, 760 mmHg). Product ID: ACM92090943. Alfa Chemistry ISO 9001:2015 Certified.
Kazusamycin A
A minor member of the leptomycin complex isolated from some streptomyces species; an hydroxylated analogue of leptomycin B, a nuclear export inhibitor; exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. Synonyms: 3-HYDROXYLEPTOMYCIN B; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-; CL 1957B, PD 114721. Grade: >95% by HPLC. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73.
Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of Leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines and also shows strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721. Grades: Highly Purified. CAS No. 92090-94-3. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Kazusamycin B
A minor component of the leptomycin complex produced by some streptomyces sp.; an hydroxylated analogue of leptomycin A, a nuclear export inhibitor; displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice; also possesses strong antibacterial and antifungal activity. Synonyms: PD 124895; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-. Grade: >95% by HPLC. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.70.
Kazusamycin B (Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895 )
Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp. It is an hydroxylated analogue of Leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895. Grades: Highly Purified. CAS No. 107140-30-7. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
KB-05
KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1956368-15-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149461.
KB-0742
KB-0742 is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416873-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478.
KB-0742 dihydrochloride
KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416874-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478A.
KB-0742 HCl
KB-0742 is an orally bioavailable, selective CDK9 inhibitor with potent anti-tumor activity in CRPC models. In 22Rv1 cells, KB-0742 rapidly downregulates nascent transcription, preferentially depleting short half-life transcripts and AR-driven oncogenic programs. In vivo, oral administration of KB-0742 significantly reduced tumor growth in CRPC, supporting CDK9 inhibition as a promising therapeutic strategy to target AR dependence in CRPC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KB-0742; KB0742; KB 0742 2HCl; KB 0742 dihydrochloride; KB 0742 hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2416874-75-2. Molecular formula: C16H27Cl2N5. Mole weight: 360.33. Purity: >98%. IUPACName: (1S,3S)-N1-(5-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine dihydrochloride. Canonical SMILES: CCC(CC)C1=NC2=CC=NN2C(N[C@@H]3C[C@@H](N)CC3)=C1.Cl.Cl. Product ID: ACM2416874752. Alfa Chemistry ISO 9001:2015 Certified.
k(Biotin)-rfarkgslrqknv
k(Biotin)-rfarkgslrqknv. Uses: Designed for use in research and industrial production. Additional or Alternative Names: K(BIOTIN)-RFARKGSLRQKNV;LYS(BIOTIN)-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH;[SER25]-PKC (19-31), BIOTINYLATED;biocytin-(ser25)-protein kinase*C fragment 19-31;BIOCYTIN-(SER25)-PROTEIN KINASE C &;[Ser25]-Protein KinaseC fragment 19-. Product Category: Heterocyclic Organic Compound. CAS No. 177966-62-0. Molecular formula: C83H144N30O20S. Mole weight: 1914.29. Product ID: ACM177966620. Alfa Chemistry ISO 9001:2015 Certified.
K(BIOTIN)-RFARKGSLRQKNV
K(BIOTIN)-RFARKGSLRQKNV. Synonyms: K(BIOTIN)-RFARKGSLRQKNV; LYS(BIOTIN)-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH; [SER25]-PKC (19-31), BIOTINYLATED; biocytin-(ser25)-protein kinase*C fragment 19-31; BIOCYTIN-(SER25)-PROTEIN KINASE C &; [Ser25]-Protein KinaseC fragment 19-. CAS No. 177966-62-0. Molecular formula: C83H144N30O20S. Mole weight: 1914.29.
kb NB 142-70
kb NB 142-70. Group: Biochemicals. Grades: Purified. CAS No. 1233533-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.