A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
kappa-Cyclodextrin is a prevalent cyclic sugar compound found in nature. Its chief purpose remains optimizing drug solubility, stability and bioavailability through efficient encapsulation. Synonyms: Cyclomaltopentadecaose; CD15. CAS No. 156510-99-5. Molecular formula: C90H150O75. Mole weight: 2432.1.
Kapurimycin A1
It is originally isolated from Str. sp. DO-15. Kapurimycin A1 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: [8-(Acetyloxy)-12-hydroxy-2-(2-methyl-3-propyloxiran-2-yl)-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. CAS No. 132412-65-8. Molecular formula: C27H26O9. Mole weight: 494.49.
Kapurimycin A2
It is originally isolated from Str. sp. DO-15. Kapurimycin A2 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: 8-Acetyloxy-2-(3-ethyl-2-methyloxiran-2-yl)-8,9,10,11-tetrahydro-12-hydroxy-4,11-dioxo-4H-anthra[1,2-b]pyran-5-acetic acid; [8-(Acetyloxy)-2-(3-ethyl-2-methyloxiran-2-yl)-12-hydroxy-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. Grades: ≥98%. CAS No. 132412-64-7. Molecular formula: C26H24O9. Mole weight: 480.46.
Kapurimycin a3
Heterocyclic Organic Compound. CAS No. 129966-45-6. Catalog: ACM129966456.
Kapurimycin A3
It is originally isolated from Str. sp. DO-15. Kapurimycin A3 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: 4H-Anthra(1,2-b)pyran-5-acetic acid, 8-(acetyloxy)-8,9,10,11-tetraahydro-12-hydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,11-dioxo-. Grades: >98%. CAS No. 129966-45-6. Molecular formula: C27H24O9. Mole weight: 492.47.
Karakanine
Karakanine is a diterpenoid alkaloid that has been used in Chinese medicine for the treatment of diabetes. It inhibits glycogen synthesis and increases blood glucose levels by blocking the production of insulin. Karakanine also possesses anti-diabetic properties, as it is able to inhibit the synthesis of cholesterol. Karakanine can be extracted from plants such as Acorus calamus, Rhizoma coptidis, and Rhizoma zingiberis. This compound can be identified using analytical methods such as nuclear magnetic resonance spectroscopy that reveal its chemical structure. Group: Other alkaloids. CAS No. 50656-90-1. Molecular formula: C22H33NO4. Mole weight: 375.5 g/mol. Catalog: ACM50656901.
Karakoline
Alkaloid , from plants of the Ranunculaceae family. Ganglioblocker; nicotinic receptor antagonist; hypotensive; presents micromolar affinity at brain a Bungarotoxin-sensitive nAChR. (See attached sheet.). Synonyms: (16S)-20-Ethyl-16-methoxy-4-methylaconitane-1α,8,14α-triol. Grades: 97% (TLC). CAS No. 39089-30-0. Molecular formula: C22H35O4N. Mole weight: 377.52.
Karalicin
Karalicin is produced by the strain of Pseudomonus fluorescens/putida SS-3. It inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC50 (μg/mL) of 0.004, 0.008, 0.016 and 0.016. Synonyms: 3-O-Acetyl-1-deoxy-1-(4-methoxyphenyl)pentitol. Molecular formula: C14H20O6. Mole weight: 284.30.
Karanjin - Product ID: NST-10-199. Category: Flavonoids. Alternative Names: Derisom. Purity: 98%. Test method: HPLC. CAS No. 521-88-0. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White Powder. Molecular formula: C18H12O4. Mole weight: 292.29. Storage: +2 +8 °C.
Karanjin
Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research [1]. Uses: Scientific research. Group: Natural products. CAS No. 521-88-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2534.
Karenitecin
Karenitecin, also known as Cositecan, is a synthetic silicon-containing agent related to camptothecin with antineoplastic properties. Karenitecin stabilizes the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks and consequently triggering apoptosis. Because it is lipophilic, karenitecin exhibits enhanced tissue penetration and bio-availability compared to water-soluble camptothecins. Synonyms: Cositecan; BNP 1350; (4S)-4-Ethyl-4-hydroxy-11-[2-(trimethylsilyl)ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 7-[2-(Trimethylsilyl)ethyl]camptothecin; DB 172; MCC 12824; (S)-4-ethyl-4-hydroxy-11-(2-(trimethylsilyl)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-(trimethylsilyl)ethyl]-, (4S)-. Grades: ≥98%. CAS No. 203923-89-1. Molecular formula: C25H28N2O4Si. Mole weight: 448.59.
Karl-Fischer Reagent (Titraquant 2)
1lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 24055880-1lt. See USA prepack pricing.
Karl-Fischer Reagent (Titraquant 2)
2.5lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 24055880-2.5lt. See USA prepack pricing.
Karl-Fischer Reagent (Uniquant 5)
1lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 90005253-1lt. See USA prepack pricing.
Karl-Fischer Reagent (Uniquant 5)
2.5lt Pack Size. Group: Analytical Reagents. Formula: N/A. Prepack ID 90005253-2.5lt. See USA prepack pricing.
Karl-Fischer working medium K solvent
1lt Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators, Water Analysis. Formula: N/A. Prepack ID 34496486-1lt. See USA prepack pricing.
KAR2, is a compound in smoke responsible for promoting the seed germination of a wide range of plant species. Synonyms: KAR2. Grades: 98%. CAS No. 857054-03-6. Molecular formula: C7H4O3. Mole weight: 136.10.
Karrikinolide 3-ethyl ester
Karrikinolide 3-ethyl ester has been used in the synthesis of butanolide seed germination stimulants. Synonyms: 2-oxo-2H-furo[2,3-c]pyran-3-carboxylic acid, ethyl ester. Grades: >95% by HPLC. CAS No. 1030604-40-0. Molecular formula: C10H8O5. Mole weight: 208.17.
Kartogenin
Kartogenin. Group: Biochemicals. Grades: Purified. CAS No. 4727-31-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Kartogenin
Kartogenin (KGN) is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN. CAS No. 4727-31-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16268.
Kartogenin
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBF&beta. Synonyms: KGN; 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid; 2-[(4-phenylphenyl)carbamoyl]benzoic acid. Grades: >98%. CAS No. 4727-31-5. Molecular formula: C20H15NO3. Mole weight: 317.344.
A cell-permeable biphenyl carbamoyl benzoate compound that potently induces the differentiation of human mesenchymal stem cells (hMSCs) into chondrocytes (EC500nM). Reversibly binds to the FC-1 fragment of filamin A and disrupts its association with CBFB leading to nuclear localization of CBFB and binding to runt-related transcription factor (RUNX) to regulate chondrogenesis. Also reported to inhibit cytokine-induced release of nitric oxide (NO) and glycosaminoglycan (GAG). Exhibits chondroprotective properties and promotes cartilage repair in murine osteoarthritis models. Shown to up-regulate the levels of TIMP1, collagen, and aggrecan thereby blocking further matrix breaown without affecting the activities of MMP-3, MMP-13, and aggrecanase in primary chondrocytes or hMSCs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??NO?, Molecular Weight: 317.3. US Biological Life Sciences.
Worldwide
Kartogenin sodium
Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN sodium. CAS No. 1401168-39-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-16268A.
Kasseptin 1Ma
Kasseptin 1Ma is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Leu-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Val-Thr-Asn-Ala-Leu-NH2. Molecular formula: C92H151N25O23. Mole weight: 1975.37.
Kasseptin 1Mb
Kasseptin 1Mb is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Phe-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Ser-Ala-Ile-Lys-Asn-Ala-Leu-NH2. Molecular formula: C97H155N25O22. Mole weight: 2023.46.
Kasseptin 1Mc
Kasseptin 1Mc is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Val-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Ser-Ala-Ile-Lys-Asn-Ala-Leu-NH2. Molecular formula: C93H155N25O22. Mole weight: 1975.42.
Kasseptin 1Md
Kasseptin 1Md is an antibacterial peptide isolated from Kassina maculata (spotted running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ile-Ile-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Ile-Lys-Asn-Thr-Phe-NH2. Grades: 95.7%. Molecular formula: C96H160N26O23. Mole weight: 2046.50.
Kassinatuerin-1
Kassinatuerin-1 is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: H-Gly-Phe-Met-Lys-Tyr-Ile-Gly-Pro-Leu-Ile-Pro-His-Ala-Val-Lys-Ala-Ile-Ser-Asp-Leu-Ile-NH2. Grades: 96.0%. Molecular formula: C109H176N26O25S. Mole weight: 2282.82.
Kassinatuerin-2
Kassinatuerin-2 is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: H-Phe-Ile-Gln-Tyr-Leu-Ala-Pro-Leu-Ile-Pro-His-Ala-Val-Lys-Ala-Ile-Ser-Asp-Leu-Ile-NH2. Grades: 95.8%. Molecular formula: C108H173N25O25. Mole weight: 2221.72.
Kassinatuerin-2Md
Kassinatuerin-2Md is an antibacterial peptide isolated from Kassina senegalensis (Senegal running frog). It has activity against gram-positive bacteria. Synonyms: Phe-Ile-Gly-Ala-Ile-Ala-Ala-Ala-Leu-Pro-His-Val-Ile-Asn-Ala-Ile-Lys-Asn-Thr-Phe. Grades: 96.0%.
Kassinin
Kassinin, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signalling and shows selectivity for NK2 over NK1 in mammals. Uses: Neurotransmitter agents. Synonyms: CID45749; Kassinin. CAS No. 63968-82-1. Molecular formula: C59H95N15O18S. Mole weight: 1334.54.
Kassinin acetate
Kassinin acetate, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signaling and shows selectivity for NK2 over NK1 in mammals. Synonyms: H-Asp-Val-Pro-Lys-Ser-Asp-Gln-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-α-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-methioninamide acetate. Grades: ≥95%. Molecular formula: C61H99N15O20S. Mole weight: 1394.59.
Kassorin-S
Kassorin-S is an antibacterial peptide isolated from Kassina senegalensis. Kassorin-S has antibacterial activity against Staphylococcus aureus. Synonyms: Phe-Leu-Gly-Gly-Ile-Leu-Asn-Thr-Ile-Thr-Gly-Leu-Leu-NH2. Molecular formula: C63H107N15O16. Mole weight: 1330.64.
Kasstasin
Kasstasin is an antibacterial peptide isolated from Kassina maculata (spotted running frog). Synonyms: Ile-Lys-Glu-Leu-Leu-Pro-His-Leu-Ser-Gly-Ile-Ile-Asp-Ser-Val-Ala-Asn-Ala-Ile-Lys.
Kastle-Meyer Reagent, in dropper bottle, Laboratory Grade, 30 mL
Notes: 2% phenolphthalein in 20% potassium hydroxide solution. Storage Code: White; corrosive. Uses: use with hydrogen peroxide for presumptive blood tests. Grades: chem-grade laboratory. Product ID: 871300. -- SOLD FOR EDUCATIONAL USE ONLY --
Kasugamycin
It is produced by the strain of Str. sugaensis M-388 (ATCC-15714, -15715). Kasugamycin has antibacterial properties against certain bacteria and fungi. Synonyms: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-; 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol; Kasu B; Kasumin 2L; Kasumin 4WP; Kasumin L; KSM; NSC 100858. Grades: ≥95%. CAS No. 6980-18-3. Molecular formula: C14H25N3O9. Mole weight: 379.36.
Kasugamycin HCl
Kasugamycin HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 19408-46-9. Pack Sizes: 500g, 1kg, 2kg. US Biological Life Sciences.
Worldwide
Kasugamycin hydrochloride
Kasugamycin hydrochloride is an aminoglycoside antibiotic produced by Streptomyces. It is a broad spectrum antifungal used against yeast and pathogenic fungi such as M. Grisea. Synonyms: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, hydrochloride (1:1); D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, monohydrochloride; Kasugamycin, monohydrochloride; Kasumin. Grades: ≥73.5%. CAS No. 19408-46-9. Molecular formula: C14H26ClN3O9. Mole weight: 415.82.
Kasugamycin hydrochloride
Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ksg hydrochloride. CAS No. 19408-46-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-B1864A.
Kasugamycin hydrochloride hydrate
Kasugamycin, an aminoglycosidic antibiotic, inhibits protein synthesis by interacting with the 30S ribosomal subunit. The mechanism of inhibition of protein synthesis seems to be different from that of other aminoglycosides such as streptomycin, kanamycin. Synonyms: 2-amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2S,3S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid;hydrate;hydrochloride UNII-5A9BN7V7QL 5A9BN7V7QL SCHEMBL69506 200132-83-8. CAS No. 200132-83-8. Molecular formula: C14H28ClN3O10. Mole weight: 433.84.
Kasugamycin hydrochloride hydrate
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ksg hydrochloride hydrate. CAS No. 200132-83-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1864B.
KAT681
KAT681 is a novel liver-selective thyromimetic displaying strong hypolipidemic properties without cardio-toxic effects. Synonyms: T 0681; T-0681; T0681; Propanoic acid, 3-[[4-[3-[(4-fluorophenyl)?hydroxymethyl]?-4-hydroxyphenoxy]?-3,?5-dimethylphenyl]?amino]?-3-oxo-, sodium salt (1:1). CAS No. 373641-87-3. Molecular formula: C24H22FNNaO6. Mole weight: 462.42.
Katacalcin
Katacalcin is a second potent plasma calcium-lowering peptide that may be a useful marker for the detection of medullary thyroid carcinoma. Uses: Calcium-regulating hormones and agents. Synonyms: PDN 21; H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH; L-alpha-aspartyl-L-methionyl-L-seryl-L-seryl-L-alpha-aspartyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-prolyl-L-histidyl-L-valyl-L-seryl-L-methionyl-L-prolyl-L-glutaminyl-L-asparagyl-L-alanyl-L-asparagine; Calcitonin C-Terminal Flanking Peptide (human). Grades: ≥95%. CAS No. 85916-47-8. Molecular formula: C97H154N34O36S2. Mole weight: 2436.59.
Katacalcin
Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PDN 21. CAS No. 85916-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0149.
Katanosin A
Katanosin A is a peptide antibiotic originally isolated from Cytophaga sp. PBJ-5356. It has anti-gram-positive bacterial effect. Synonyms: L-Serine, N-[threo-3-hydroxy-N2-[N-[N-[N-[N2-[N-[threo-3-hydroxy-N-[threo-b-hydroxy-N-(N-D-leucyl-L-leucyl)-L-phenylalanyl]-L-leucyl]-L-leucyl]-D-arginyl]-L-valyl]-L-allothreonyl]glycyl]-L-asparaginyl]-,b1-lactone. CAS No. 116103-86-7. Molecular formula: C57H95N15O17. Mole weight: 1262.45.
Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 6730-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N1469.
Kava Extract
Kava extract is prepared from the root of medicina plant kava, native to the Pacific islands. Kava extract powder is used as a herbal remedy in the form of an extract called seanol, a polyphenolic extract. Kava extract is used frequently in herbal medicine to treat anxiety and insomnia. Kava extract is commonly prescribed by herbalists and alternative medicine practitioners for all types of anxiety disorders. Group: Others. Kava Extract; Piper Methysticum. Cat No: EXTC-051.
Kavain
Kavain. Group: Biochemicals. Grades: Plant Grade. CAS No. 500-64-1. Pack Sizes: 10mg. Molecular Formula: C14H14O3, Molecular Weight: 230.26. US Biological Life Sciences.
Worldwide
Kavain
Kavain is a class of kavalactone isolated from Piper methysticum , which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor [1]. Uses: Scientific research. Group: Natural products. CAS No. 3155-48-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N2096.
A minor member of the leptomycin complex isolated from some streptomyces species; an hydroxylated analogue of leptomycin B, a nuclear export inhibitor; exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. Synonyms: 3-HYDROXYLEPTOMYCIN B; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-; CL 1957B, PD 114721. Grades: >95% by HPLC. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73.
Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of Leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines and also shows strong antibacterial and antifungal activity. Group: Biochemicals. Alternative Names: Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721. Grades: Highly Purified. CAS No. 92090-94-3. Pack Sizes: 100ug. US Biological Life Sciences.