American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Ultrazur ® Quick inquiry Where to buy Suppliers range | Ultrazur ®. CAS No. MIXTURE. VIGON Item # 502682. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Ulvan polysaccharide Quick inquiry Where to buy Suppliers range |  | |
| Ulvan - Ulva armoricana-winter-heavy Quick inquiry Where to buy Suppliers range | Cas No. 164252-34-0. | |
| Ulvan - Ulva rotondata-Autumn Quick inquiry Where to buy Suppliers range | Ulvan - Ulva rotondata-Autumn, originating from the autumnal Ulva rotondata, showcases great application in studying a multitude of ailments, encompassing cancer, diabetes and cardiovascular maladies alike. Synonyms: Sulfated xylorhamnoglycuronan; Ulvan MW. Molecular formula: (C6H9O3SO3)n. | |
| Ulvan - Ulva rotondata-Summer Quick inquiry Where to buy Suppliers range | Ulvan, derived from the Ulva rotondata-Summer algae, is a remarkable natural polysaccharide. This bioactive compound exhibits immense application as a compound owing to its multifaceted anti-inflammatory and antioxidant characteristics. Synonyms: Sulfated xylorhamnoglycuronan; Ulvan MW. Molecular formula: (C6H9O3SO3)n. | |
| UM-164 Quick inquiry Where to buy Suppliers range | UM-164 is an inhibitor of Src and p38 MAPK kinases with Kds values of 2.7, 2.2, and 5.5 nM for c-Src, p38α, and p38β, respectively. It inhibits cell growth in a panel of triple-negative breast cancer (TNBC) cell lines (IC50s = 6.1-260 nM) and in a patient-derived TNBC cell line (IC50 = 320 nM). Uses: Protein kinase inhibitors. Synonyms: DAS-DFGO-II; 2-[[6-[4- (2-hydroxyethyl) piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-N-[2-methyl-5-[[3- (trifluoromethyl) benzoyl]amino]phenyl]-1, 3-thiazole-5-carboxamide. Grades: ≥98%. CAS No. 903564-48-7. Molecular formula: C30H31F3N8O3S. Mole weight: 640.68. | |
| UMB-32 Quick inquiry Where to buy Suppliers range | UMB-32 is an inhibitor of the BET bromodomain BRD4 (Kd = 550 nM; IC50 = 637 nM) and the bromodomain-containing transcription factor TAF1 (Kd = 560 nM) and TAF1L (Kd = 1.3 μM). Synonyms: N-Tert-Butyl-2-[4-(3,5-Dimethyl-1,2-Oxazol-4-Yl)phenyl]imidazo[1,2-A]pyrazin-3-Amine. Grades: ≥98%. CAS No. 1635437-39-6. Molecular formula: C21H23N5O. Mole weight: 361.4. | |
| UMB 68 Quick inquiry Where to buy Suppliers range | UMB 68 is a GHB receptor ligand exhibiting no affinity for GABA(A) or GABA(B) receptors. UMB 68 was shown not to exhibit GHB-like behavioral effects in vivo. Synonyms: UMB68, UMB-68, UMB 68, UMB-68 sodium; Sodium 4-Hydroxy-4methylpentanoate. CAS No. 581099-89-0. Molecular formula: C6H11NaO3. Mole weight: 154.14. | |
| Umbelliferone Quick inquiry Where to buy Suppliers range | Umbelliferone, which is extracted from the root of Angelica biserrata (Shan et Yuan) Yuan et Shan, also known as 7-hydroxycoumarin, hydrangine, skimmetine, and beta-umbelliferone, is a widespread natural product of the coumarin family. It is a yellowish-white crystalline solid that has a slight solubility in hot water, but high solubility in ethanol. Uses: Anti-nociceptive, anti-inflammatory,anti-cancer, anti-oxidant. Synonyms: 7-hydroxy-1-benzopyran-2-one;7-Hydroxycoumarin. Grades: >98%. CAS No. 93-35-6. Molecular formula: C9H6O3. Mole weight: 162.1. | |
| Umbelliferone 7-O-Rutinoside Quick inquiry Where to buy Suppliers range | An impurity of Umbelliferone. Umbelliferone is a metabolite of Coumarin. Umbelliferone is used as a sunscreen agent for its ultraviolet activity. CAS No. 135064-04-9. Molecular formula: C21H26O13. Mole weight: 486.43. | |
| Umbelliferone 99+% (HPLC) Quick inquiry Where to buy Suppliers range | Umbelliferone 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 93-35-6. Pack Sizes: 100g, 250g, 25g, 1Kg. US Biological Life Sciences. |  Worldwide |
| Umbellulone Quick inquiry Where to buy Suppliers range | Offensive principle of the so-called "headache tree". Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitoningene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 546-78-1. Pack Sizes: 10mg. Molecular Formula: C10H14O. US Biological Life Sciences. | Worldwide |
| Umbilical Vein Endothelial Cells, Human (Frozen) Quick inquiry Where to buy Suppliers range | Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Umbilical Vein Endothelial Cells, Human (T-25 flask) Quick inquiry Where to buy Suppliers range | Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| Umbilicaric acid Quick inquiry Where to buy Suppliers range | Umbilicaric acid is an organic polyphenolic carboxylic acid. CAS No. 30666-92-3. Molecular formula: C25H22O10. Mole weight: 482.44. | |
| Umbralisib Quick inquiry Where to buy Suppliers range | Umbralisib is an orally bioavailable and selective PI3K delta inhibitor that targets delta isoform with nanomolar potency, which is approximately 1000-fold selective over alpha isoform, >30-50 fold over beta isoform and >15-50 fold over gamma isoforms. Umbralisib is developed for lymphoma therapy. Synonyms: TGR-1202; TGR 1202; TGR1202; RP5264; 2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one. CAS No. 1532533-67-7. Molecular formula: C31H24F3N5O3. Mole weight: 571.5. | |
| Umckalin Quick inquiry Where to buy Suppliers range | Umckalin. Group: Heterocyclic Organic Compound. Alternative Names: UMCKALIN;5,6-Dimethoxy-7-hydroxy-2H-1-benzopyran-2-one;7-Hydroxy-5,6-dimethoxy-2H-1-benzopyran-2-one;Umckaline;2H-1-Benzopyran-2-one, 7-hydroxy-5,6-dimethoxy-;UMCKALIN(SH);5-Methoxyscopoletin;7-Hydroxy-5,6-dimethoxycoumarin. CAS No. 43053-62-9. Molecular formula: C11H10O5. Mole weight: 0. Symbol: GHS07. Melting Point: 147-148.5? (water , methanol ). Density: 1.358±0.06 g/cm3 (20 ºC 760 Torr). Safty Description: 26. Hazard statements: Xn. Supplemental Hazard Statements: H302-H319. |  |
| Umeclidinium bromide Quick inquiry Where to buy Suppliers range | Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). Synonyms: GSK-573719, GSK573719, GSK 573719, GSK-573719A, GSK573719A, GSK 573719A, Incruse Ellipta, Umeclidinium bromide. Grades: 0.99. CAS No. 869113-09-7. Molecular formula: C29H34BrNO2. Mole weight: 508.5. | |
| UMI-77 Quick inquiry Where to buy Suppliers range | UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. Synonyms: UMI-77, UMI77, UMI 77. Grades: >98%. CAS No. 518303-20-3. Molecular formula: C18H14BrNO5S2. Mole weight: 468.34. | |
| Umicore Metal Precursors Kit Quick inquiry Where to buy Suppliers range | Umicore Metal Precursors Kit. | |
| Umifenovir Quick inquiry Where to buy Suppliers range | Arbidol is an antiviral agent using for the treatment of influenza infection in Russia and China. It inhibits membrane fusion and prevents contact between the virus and target host cells. Fusion between the viral capsid and the cell membrane of the target cell is inhibited and this prevents viral entry to the target cell. Although some Russian studies have shown it to be effective, it is not approved for use in Western countries. Synonyms: Arbidol; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grades: ≥95%. CAS No. 131707-25-0. Molecular formula: C22H25BrN2O3S. Mole weight: 477.41. | |
| Umifenovir Glucuronide Quick inquiry Where to buy Suppliers range | Umifenovir Glucuronide is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylthio)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic Acid; Arbidol O-Glucuronide; 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic acid; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-(β-D-glucopyranuronosyloxy)-1-methyl-2-[(phenylthio)methyl]-, ethyl ester. Grades: >98%. CAS No. 1130900-96-7. Molecular formula: C28H33BrN2O9S. Mole weight: 653.54. | |
| Umifenovir Sulfate Quick inquiry Where to buy Suppliers range | Umifenovir Sulfate is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: Ethyl 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylsulfanyl)methyl]-5-(sulfooxy)-1H-indole-3-carboxylate; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-, 3-ethyl ester; 3-Ethyl Ester 6-Bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-1H-indole-3-carboxylic Acid; Arbidol Sulfate. Grades: >98%. CAS No. 1443454-70-3. Molecular formula: C22H25BrN2O6S2. Mole weight: 557.48. | |
| Umirolimus Quick inquiry Where to buy Suppliers range | A semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group. It is one of the most hydrophobic tacrolimus analogues. It binds to the cytosolic FK-binding protein 12 (FKBP12) to inhibit the mammalian target of rapamycin (mTOR) pathway. Synonyms: Biolimus; Biolimus A9; TRM 986; 42-O-(2-Ethoxyethyl)rapamycin. Grades: >95% by HPLC. CAS No. 851536-75-9. Molecular formula: C55H87NO14. Mole weight: 986.28. | |
| UMP/CMP kinase Quick inquiry Where to buy Suppliers range | This eukaryotic enzyme is a bifunctional enzyme that catalyses the phosphorylation of both CMP and UMP with similar efficiency. dCMP can also act as acceptor. Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, CMP kinase and EC 2.7.4.22, UMP kinase. Group: Enzymes. Synonyms: cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMP kinase; deoxycytidine monophosphokinase; UMP-CMP kinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Enzyme Commission Number: EC 2.7.4.14. CAS No. 37278-21-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3195; UMP/CMP kinase; EC 2.7.4.14; 37278-21-0; cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMP kinase; deoxycytidine monophosphokinase; UMP-CMP kinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Cat No: EXWM-3195. |  |
| UMP-CP Quick inquiry Where to buy Suppliers range | UMP-CP is a non-hydrolytic analogue of UDP and a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Uridine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 732921-73-2. Molecular formula: C10H16N2O11P2 (free acid). Mole weight: 402.2 (free acid). | |
| UMP kinase Quick inquiry Where to buy Suppliers range | This enzyme is strictly specific for UMP as substrate and is used by prokaryotes in the de novo synthesis of pyrimidines, in contrast to eukaryotes, which use the dual-specificity enzyme UMP/CMP kinase (EC 2.7.4.14) for the same purpose. This enzyme is the subject of feedback regulation, being inhibited by UTP and activated by GTP. Group: Enzymes. Synonyms: uridylate kinase; UMPK; uridine monophosphate kinase; PyrH; UMP-kinase; SmbA. Enzyme Commission Number: EC 2.7.4.22. CAS No. 9036-23-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3204; UMP kinase; EC 2.7.4.22; 9036-23-1; uridylate kinase; UMPK; uridine monophosphate kinase; PyrH; UMP-kinase; SmbA. Cat No: EXWM-3204. | |
| UN6HA1 60L Quick inquiry Where to buy Suppliers range | 1ea Pack Size. Group: Equipment. Prepack ID 90027219-1ea. See USA prepack pricing. |  |
| UNBS3157 Quick inquiry Where to buy Suppliers range | UNBS3157 is a DNA intercalator, and a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. Amonafide, a naphthalimide which binds to DNA by intercalation and poisons topoisomerase IIalpha, has demonstrated activity in phase II breast cancer trials, but has failed thus far to enter clinical phase III because of dose-limiting bone marrow toxicity. Synonyms: UNBS 3157; UNBS-3157. Grades: 98%. CAS No. 868962-26-9. Molecular formula: C19H17Cl3N4O4. Mole weight: 471.72. | |
| UNBS5162 Quick inquiry Where to buy Suppliers range | UNBS5162 is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Synonyms: [2-[2-(dimethylamino)ethyl]-1,3-dioxobenzo[de]isoquinolin-5-yl]urea; UNBS 5162; UNBS-5162; UNBS5162. CAS No. 956590-23-1. Molecular formula: C17H18N4O3. Mole weight: 326.35. | |
| UNC0224 Quick inquiry Where to buy Suppliers range | The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM. Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM. UNC0224 also inhibits GLP, a closely-related H3K9 HMTase, with assay-dependent IC50 values of 20-58 nM, but is more than 1,000-fold selective against SET7/9 (a H3K4 HMTase) and SET8 (a H4K20 HMTase). Synonyms: UNC0224; UNC-0224; UNC 0224; 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine. Grades: >98%. CAS No. 1197196-48-7. Molecular formula: C26H43N7O2. Mole weight: 485.67. | |
| UNC 0224 Quick inquiry Where to buy Suppliers range | UNC 0224. Group: Biochemicals. Grades: Purified. CAS No. 1197196-48-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UNC0321 Quick inquiry Where to buy Suppliers range | UNC0321 is the first G9a inhibitor with picomolar potency and the most potent G9a inhibitor to date. Protein lysine methyltransferase G9a, which catalyzes methylation of lysine 9 of histone H3 (H3K9) and lysine 373 (K373) of p53, is overexpressed in human cancers. Genetic knockdown of G9a inhibits cancer cell growth, and the dimethylation of p53 K373 results in the inactivation of p53. Synonyms: UNC0321, UNC-0321, UNC 0321, CHEMBL1214066, CHEBI:785916, UNC0321 (trifluoroacetate salt), NCGC0018778901, KB81388. Grades: >98%. CAS No. 1238673-32-9. Molecular formula: C27H45N7O3. Mole weight: 515.69. | |
| UNC0321 (TFA Salt) Quick inquiry Where to buy Suppliers range | UNC0321 (trifluoroacetate salt) is a selective histone lysine methyltransferase (HMTase) inhibitor for G9a and GLP (also known as EHMT1), with IC50 of 6nM and 15nM, respectively. It is more than 40,000-fold more selective for G9a and GLP vs. SET7/9, SET8, PRMT3, or JMJD2E. Group: Biochemicals. Alternative Names: 4-Quinazolinamine, 7-[2-[2- (dimethylamino) ethoxy]ethoxy]-2- (hexahydro-4-methyl-1H-1, 4-diazepin-1-yl) -6-methoxy-N- (1-methyl-4-piperidinyl) -, trifluoroacetate. Grades: Highly Purified. CAS No. 1238673-32-9 (free base). Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| UNC0379 Quick inquiry Where to buy Suppliers range | UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. UNC0379 is active in multiple biochemical assays. Its affinity to SETD8 was confirmed by ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) studies. Importantly, UNC0379 is selective for SETD8 over 15 other methyltransferases. Synonyms: UNC0379, UNC-0379, UNC 0379. Grades: 0.98. CAS No. 1620401-82-2. Molecular formula: C23H35N5O2. Mole weight: 413.566. | |
| UNC0379 trifluoroacetate Quick inquiry Where to buy Suppliers range | UNC0379 trifluoroacetate is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM; selective over 15 other methyltransferases. Synonyms: UNC-0379 trifluoroacetate; UNC 0379 trifluoroacetate; UNC0379 trifluoroacetate. Grades: >98%. CAS No. 1620401-83-3. Molecular formula: C25H36F3N5O4. Mole weight: 527.58. | |
| UNC-0631 Quick inquiry Where to buy Suppliers range | UNC 0631 is a potent G9a inhibitor with IC50 value of 4 nM. Synonyms: UNC0631, UNC 0631, UNC-0631. CAS No. 1320288-19-4. Molecular formula: C37H61N7O2. Mole weight: 635.942. | |
| UNC-0638 Quick inquiry Where to buy Suppliers range | UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity. UNC0638 markedly reduced the clonogenicity of MCF7 cells, reduced the abundance of H3K9me2 marks at promoters of known G9a-regulated endogenous genes and disproportionately affected several genomic loci encoding microRNAs. Synonyms: UNC0638, UNC-0638, UNC 0638. Grades: 0.98. CAS No. 1255580-76-7. Molecular formula: C30H47N5O2. Mole weight: 509.739. | |
| UNC0638 hydrate Quick inquiry Where to buy Suppliers range | UNC 0638 is a selective inhibitor of G9a/EHMT2 and GLP histone lysine methyltransferases (IC50 values are < 15 nM and 19 nM for G9a and GLP respectively, and> 10000 nM for a panel of other histone methyltransferases). UNC 0638 inhibits dimethylation of H3K9 in MCF-7 cells (IC50 = 70 nM). Synonyms: UNC 0638; UNC0638; UNC-0638; 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine. Grades: ≥99% by HPLC. CAS No. 1255517-77-1. Molecular formula: C30H49N5O3. Mole weight: 527.7. | |
| UNC0642 Quick inquiry Where to buy Suppliers range | UNC0642 is a potent, selective inhibitor of G9a/GLP with improved PK properties. Synonyms: UNC0642; UNC-0642; UNC 0642. Grades: 98%. CAS No. 1481677-78-4. Molecular formula: C29H44F2N6O2. Mole weight: 546.71. | |
| UNC0646 Quick inquiry Where to buy Suppliers range | UNC-0646 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Synonyms: UNC0646, UNC 0646, UNC-0646. Grades: 0.98. CAS No. 1320288-17-2. Molecular formula: C36H59N7O2. Mole weight: 621.915. | |
| UNC 0646 Quick inquiry Where to buy Suppliers range | UNC 0646. Group: Biochemicals. Grades: Purified. CAS No. 1320288-17-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UNC1215 Quick inquiry Where to buy Suppliers range | UNC1215 is a potent, selective antagonist of L3MBTL3 with cellular activity. UNC1215 has an IC50 of 20 nM and > 100-fold selectivity over 13 HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. Synonyms: UNC1215, UNC-1215, UNC 1215; (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone). Grades: >98%. CAS No. 1415800-43-9. Molecular formula: C32H43N5O2. Mole weight: 529.729. | |
| UNC 1215 Quick inquiry Where to buy Suppliers range | UNC 1215. Group: Biochemicals. Alternative Names: 2-Phenylamino-1, 4-[4- (pyrrolidinyl) piperidinyl) benzamide. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C32H43N5O2, Molecular Weight: 529.72. US Biological Life Sciences. | Worldwide |
| UNC1999 Quick inquiry Where to buy Suppliers range | UNC1999. Group: Biochemicals. Alternative Names: N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-Indazole-4-carboxamide. Grades: Highly Purified. CAS No. 1431612-23-5. Pack Sizes: 5mg. Molecular Formula: C33H43N7O2, Molecular Weight: 569.74. US Biological Life Sciences. | Worldwide |
| UNC-1999 Quick inquiry Where to buy Suppliers range | UNC1999, the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. UNC1999 was highly selective for EZH2 and EZH1 over a broad range of epigenetic and non-epigenetic targets. UNC1999 was orally bioavailable in mice, making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies. UNC-1999 represents a useful tools for the biomedical community to investigate the role of EZH2 and EZH1 in health and disease. Synonyms: UNC1999; UNC 1999; UNC-1999. Grades: 0.98. CAS No. 1431612-23-5. Molecular formula: C33H43N7O2. Mole weight: 569.754. | |
| UNC-2025 Quick inquiry Where to buy Suppliers range | UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that UNC-2025 has similar subnanomolar activity against Flt3, an additional important target in acute myelogenous leukemia (AML), with pharmacologically useful selectivity versus other kinases examined. Synonyms: Cyclohexanol, 4-[2-(butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-; trans-4-[2-(Butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexanol; MRX 6313; UNC 2025; UNC2025. Grades: ≥95%. CAS No. 1429881-91-3. Molecular formula: C28H40N6O. Mole weight: 476.66. | |
| UNC-2025 hydrochloride Quick inquiry Where to buy Suppliers range | UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor. Synonyms: UNC-2025 hydrochloride; UNC 2025 hydrochloride; UNC2025 hydrochloride; (1r,4r)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol hydrochloride. Grades: >98%. CAS No. 2070015-17-5. Molecular formula: C28H41ClN6O. Mole weight: 513.12. | |
| UNC2170 maleate Quick inquiry Where to buy Suppliers range | UNC2170 is a p53-Binding protein 1 (53BP1) antagonist that binds to a pocket formed by the tandem tudor domains on a 53BP1 homodimer. Synonyms: 3-bromo-N-[3-(tert-butylamino)propyl]benzamide maleate. Grades: ≥95%. Molecular formula: C14H21BrN2O·C4H4O4. Mole weight: 429.3. | |
| UNC2250 Quick inquiry Where to buy Suppliers range | UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. Treatment with UNC2250 also resulted in decreased colony-forming potential in rhabdoid and NSCLC tumor cells. The results provide a rationale for further investigation of UNC2250 for therapeutic application in patients with cancer. Synonyms: UNC-2250; UNC 2250. Grades: 98%. CAS No. 1493694-70-4. Molecular formula: C24H36N6O2. Mole weight: 440.58. | |
| UNC 2327 Quick inquiry Where to buy Suppliers range | UNC 2327. Group: Biochemicals. Grades: Purified. CAS No. 1426152-53-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UNC 2327 Quick inquiry Where to buy Suppliers range | UNC 2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 230 nM). Synonyms: UNC2327; UNC-2327; UNC 2327; N-1,2,3-Benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]urea. Grades: ≥99% by HPLC. CAS No. 1426152-53-5. Molecular formula: C14H17N5O2S. Mole weight: 319.38. | |
| UNC 2399 Quick inquiry Where to buy Suppliers range | | |
| UNC 2400 Quick inquiry Where to buy Suppliers range | UNC 2400 is a negative control of UNC 1999 that displays 1000-fold lower potency than active analog (IC50 = 62 and >200 μM for EZH1 and EZH2, respectively). Synonyms: UNC2400; UNC-2400; UNC 2400; N-[(1,2-Dihydro-1,6-dimethyl-2-oxo-4-propyl-3-pyridinyl)methyl]-N-methyl-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide. Grades: ≥98% by HPLC. CAS No. 1433200-49-7. Molecular formula: C35H47N7O2. Mole weight: 597.79. | |
| UNC2541 Quick inquiry Where to buy Suppliers range | UNC2541 is a potent specific inhibitor of Mer tyrosine kinase (MerTK). Synonyms: UNC-2541; UNC 2541. Grades: ≥98% by HPLC. CAS No. 1612782-86-1. Molecular formula: C24H34FN7O2. Mole weight: 471.6. | |
| UNC2881 Quick inquiry Where to buy Suppliers range | UNC2881 is a potent Mer kinase inhibitor. UNC2281 inhibits steady-state Mer kinase phosphorylation with an IC50 value of 22 nM. Treatment with UNC2281 is also sufficient to block EGF-mediated stimulation of a chimeric receptor containing the intracellular domain of Mer fused to the extracellular domain of EGFR. In addition, UNC2881 potently inhibits collagen-induced platelet aggregation, suggesting that this class of inhibitors may have utility for prevention and/or treatment of pathologic thrombosis. Synonyms: UNC2881; UNC 2881; UNC-2881. Grades: 98%. CAS No. 1493764-08-1. Molecular formula: C25H33N7O2. Mole weight: 463.586. | |
| UNC 3230 Quick inquiry Where to buy Suppliers range | UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM), displaying selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. UNC 3230 decreases PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. UNC 3230 exhibits antinociceptive effects in mouse models of chronic pain. Synonyms: UNC3230; UNC-3230; UNC 3230; 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide. Grades: ≥99% by HPLC. CAS No. 1031602-63-7. Molecular formula: C17H20N4O2S. Mole weight: 344.43. | |
| UNC 3230 Quick inquiry Where to buy Suppliers range | UNC 3230. Group: Biochemicals. Grades: Purified. CAS No. 1031602-63-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UNC 3866 Quick inquiry Where to buy Suppliers range | UNC 3866 is a potent and high affinity CBX4 and CBX7 inhibitor (Ki = 94 and 97 nM, respectively) displaying > 6-fold selectivity over other CBX and CDY family members. UNC 3866 was shown to inhibit the proliferation of PC3 cells in vitro. Synonyms: UNC3866, UNC-3866, UNC 3866; N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester. CAS No. 1872382-47-2. Molecular formula: C43H66N6O8. Mole weight: 795.02. | |
| UNC569 Quick inquiry Where to buy Suppliers range | Mer proto-oncogene tyrosine kinase (MerTK) is expressed in the retinal pigment epithelium (RPE), regulates phagocytosis of shed photoreceptor outer segments (POS). UNC569 is a specific MerTK inhibitor. Synonyms: 1-[(Trans-4-Aminocyclohexyl)methyl]-N-Butyl-3-(4-Fluorophenyl)-1h-Pyrazolo[3,4-D]pyrimidin-6-Amine. Grades: 98%. CAS No. 1350547-65-7. Molecular formula: C22H29FN6. Mole weight: 396.50. | |
| UNC 669 Quick inquiry Where to buy Suppliers range | (5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone is a selective inhibitor of malignant brain tumor (MBT). Synonyms: UNC669; UNC-669. Grades: >98%. CAS No. 1314241-44-5. Molecular formula: C15H20BrN3O. Mole weight: 338.24. | |
| UNC6852 Quick inquiry Where to buy Suppliers range | UNC6852 is a selective polycomb inhibitory complex 2 (PRC2) degradation agent based on PROTAC. Synonyms: UNC-6852; UNC 6852; (2S,4R)-1-((S)-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 2688842-08-0. Molecular formula: C43H48N10O6S. Mole weight: 832.99. | |
| UNC-926 Quick inquiry Where to buy Suppliers range | UNC-926 is a methyl-lysine (Kme) reader domain inhibitor which binds to the MBT domain of L3MVTL protein (IC50 = 3.9 μM). Synonyms: UNC-926; UNC 926; UNC926; (3-bromophenyl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone. CAS No. 1184136-10-4. Molecular formula: C16H21BrN2O. Mole weight: 337.25. | |
| UNC 926 hydrochloride Quick inquiry Where to buy Suppliers range | UNC 926 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1184136-10-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| UNC 9994 hydrochloride Quick inquiry Where to buy Suppliers range | UNC 9994 hydrochloride is a β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) with antipsychotic activity in vivo. Synonyms: UNC 9994 hydrochloride; UNC9994 hydrochloride; UNC-9994 hydrochloride; 5-[3-[4-(2,3-dichlorophenyl)piperidin-1-yl]propoxy]-1,3-benzothiazole hydrochloride. Grades: 99%. CAS No. 2108826-33-9. Molecular formula: C21H22Cl2N2OS.HCl. Mole weight: 457.84. | |
| Uncarine C Quick inquiry Where to buy Suppliers range | Botanical Source: Group: Biochemicals. Alternative Names: Isospeciophylline, Pteropodine. Grades: Plant Grade. CAS No. 5629-60-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Uncarine f Quick inquiry Where to buy Suppliers range | Uncarine f. Group: Heterocyclic Organic Compound. Alternative Names: Uncarine F, 14019-66-0, C17598. Grades: 96%. CAS No. 14019-66-0. Molecular formula: C21H24N2O4. Mole weight: 368.426260 [g/mol]. IUPAC Name: methyl (1S,4aS,5aR,6R,10aS)-1-methyl-2-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3-1H-indole]-4-carboxylate. Exact Mass: 368.17400. Boiling Point: 555.2ºC at 760mmHg. Flash Point: 289.6ºC. Density: 1.33g/cm3. SMILES: CC1C2CN3CCC4 (C3CC2C (=CO1)C (=O)OC)C5=CC=CC=C5NC4=O. InChIKey: JMIAZDVHNCCPDM-PMJXBNNDSA-N. H-Bond Donor: 1. H-Bond Acceptor: 5. | |
| Uncharacterized protein C18orf8 (501-509) Quick inquiry Where to buy Suppliers range | Uncharacterized protein C18orf8 (501-509) is a 9-aa peptide. It is a componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). This peptide can be used in Ovarian carcinoma research. Synonyms: Colon cancer-associated protein Mic1 (501-509). | |
| Unconventional myosin-Ib (911-919) Quick inquiry Where to buy Suppliers range | A peptide fragment of Unconventional myosin-Ib. Unconventional myosin-Ib is a motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport. Synonyms: MYH-1c (911-919); Myosin I alpha (911-919). | |
| Undecafluorohexanoic Acid Quick inquiry Where to buy Suppliers range | Undecafluorohexanoic Acid. Group: Biochemicals. Alternative Names: Perfluorohexanoic Acid. Grades: Highly Purified. CAS No. 307-24-4. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |