A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
JWH 073 N-(4-Hydroxybutyl) β-D-Glucuronide. Group: Biochemicals. Alternative Names: 4-[3-(1-Naphthalenylcarbonyl)-1H-indol-1-yl]butyl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C29H31NO7, Molecular Weight: 505.56. US Biological Life Sciences.
Worldwide
JWH-122 4-Hydroxypentyl metabolite-D5 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-122 4-Hydroxypentyl metabolite solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-122 5-Hydroxypentyl metabolite solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-122 (Indole-d5) 5-Hydroxypentyl
JWH-122 (Indole-d5) 5-Hydroxypentyl is labelled JWH-122 5-Hydroxypentyl (J211465) which is a urinary metabolite of JWH-122. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D5NO2, Molecular Weight: 376.5. US Biological Life Sciences.
JWH-122 N-Pentanoic Acid-d4. Group: Biochemicals. Alternative Names: 5-Carboxy-JWH-122; 5-(3-(4-methyl-1-naphthoyl)-1H-indol-1-yl)pentanoic Acid-d4; MAM-2201 5-Pentanoic Acid-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H19D4NO3, Molecular Weight: 389.48. US Biological Life Sciences.
Worldwide
JWH 176
JWH 176. Group: Biochemicals. Alternative Names: 1-[(E)-(3-Pentyl-1H-inden-1-ylidene)methyl]-naphthalene. Grades: Highly Purified. CAS No. 619294-62-1. Pack Sizes: 1mg. Molecular Formula: C25H24, Molecular Weight: 324.459999999999. US Biological Life Sciences.
Worldwide
JWH-203
A cannabimimetic indole derivative that acts as both a cannabinoid receptor CB1 and CB2 agonist. Group: Biochemicals. Alternative Names: 2-(2-Chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone; JWH 203. Grades: Highly Purified. CAS No. 864445-54-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
JWH-203-d11
Labeled analogue of a cannabimimetic indole derivative that acts as both a cannabinoid receptor CB1 and CB2 agonist. Group: Biochemicals. Alternative Names: 2-(2-Chlorophenyl)-1-[1-(pentyl-d11)-1H-indol-3-yl]ethanone; JWH 203-d11. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
JWH-210 4-Hydroxypentyl metabolite-D5 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-210 4-Hydroxypentyl metabolite solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-210 5-Hydroxypentyl metabolite solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH 250
A new class of cannabimimetic indoles. Group: Biochemicals. Alternative Names: 2-(2-Methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone. Grades: Highly Purified. CAS No. 864445-43-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
JWH-250 4-Hydroxypentyl metabolite
ampule of 1 mL, certified reference material, 100 ?g/mL in methanol. Group: Certified reference materials (crms).
JWH-250 4-Hydroxypentyl metabolite-D5 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH-250 5-Hydroxypentyl metabolite solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
JWH 250-d11
Labeled JWH 250. A new class of cannabimimetic indoles. Group: Biochemicals. Alternative Names: 2-(2-Methoxyphenyl)-1-(1-(pentyl-d11)-1H-indol-3-yl)ethanone. Grades: Highly Purified. CAS No. 1346598-78-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
JWH 252
JWH 252. Group: Biochemicals. Alternative Names: 1-(2-Methyl-1-pentyl-1H-indol-3-yl)-2-(2-methylphenyl)ethanone. Grades: Highly Purified. CAS No. 864445-40-9. Pack Sizes: 10mg. Molecular Formula: C23H27NO, Molecular Weight: 333.47. US Biological Life Sciences.
Worldwide
JWH 252-d11
JWH 252-d11. Group: Biochemicals. Alternative Names: 1-(2-Methyl-1-pentyl-1H-indol-3-yl)-2-(2-methylphenyl)ethanone-d11. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H16D11NO, Molecular Weight: 344.53. US Biological Life Sciences.
Worldwide
JWH 387
JWH 387. Group: Biochemicals. Alternative Names: (4-Bromo-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone. Grades: Highly Purified. CAS No. 1366067-59-5. Pack Sizes: 10mg. Molecular Formula: C24H22BrNO, Molecular Weight: 420.34. US Biological Life Sciences.
Worldwide
JWH 387-d11
JWH 387-d11. Group: Biochemicals. Alternative Names: (4-Bromo-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone-d11. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C24H11D11BrNO, Molecular Weight: 431.41. US Biological Life Sciences.
Worldwide
JWH-398-d5
JWH-398-d5. Group: Biochemicals. Alternative Names: (4-Chloronaphthalen-1-yl)(1-(5-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)methanone; (4-Chloro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone-d5. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C24H17D5ClNO, Molecular Weight: 380.92. US Biological Life Sciences.
Worldwide
JWH 398 N-(4-Hydroxypentyl) Metabolite-d5
JWH 398 N-(4-Hydroxypentyl) Metabolite-d5. Group: Biochemicals. Alternative Names: (4-Chloronaphthalen-1-yl)(1-(4-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)methanone. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C24H17D5ClNO2, Molecular Weight: 396.92. US Biological Life Sciences.
Worldwide
JWH 412
JWH 412. Group: Biochemicals. Alternative Names: (4-Fluoro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone. Grades: Highly Purified. CAS No. 1364933-59-4. Pack Sizes: 1mg. Molecular Formula: C24H22FNO, Molecular Weight: 359.44. US Biological Life Sciences.
Worldwide
JX06
JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 729-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19564.
JX 06
JX 06 is a potent, selective and covalent pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor with IC50 values of 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively. It suppresses A549 lung cancer cell proliferation in vitro and reduces tumor volume of A549 xenografts in mice. Synonyms: JX-06; JX06; Bis(morpholinothiocarbonyl) Disulfide; 4, 4'- (Dithiodicarbonothioyl) bis[morpholine]; 4-Morpholinethiocarbonyl Disulfide; Dimorpholinethiuram Disulfide; Disulfide, bis(4-Morpholinylthioxomethyl); NSC 402538; bis(Oxydi-2,1-ethanediyl)-thiuram Disulfide. Grades: ≥98% by HPLC. CAS No. 729-46-4. Molecular formula: C10H16N2O2S4. Mole weight: 324.51.
JX-06
JX-06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 28, 49 and 313 nM for PDK2, PDK1 and PDK3, respectively). JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification. JX06, as a selective covalent inhibitor of PDK1 in cells, forms a disulfide bond with the thiol group of a conserved cysteine residue (C240) based on recognition of a hydrophobic pocket adjacent to the ATP pocket of the PDK1 enzyme. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JX-06; JX 06; JX06. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 729-46-4. Molecular formula: C10H16N2O2S4. Mole weight: 324.49. Purity: >98%. IUPACName: Bis(morpholinothiocarbonyl) disulfide. Canonical SMILES: S=C(SSC(N1CCOCC1)=S)N2CCOCC2. Product ID: ACM729464. Alfa Chemistry ISO 9001:2015 Certified. Categories: JP-06.
JX 401
JX 401. Group: Biochemicals. Grades: Purified. CAS No. 349087-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
JX 401
JX 401, cell-permeable piperidinamide compound, is a reversible and highly potent inhibitor of p38α isoform MAP kinase containing a 4-benzylpiperidine motif. Its IC50 value is 32 nM and displays no activity on the p38γ isoform. It effectively blocks the differentiation of L8 myoblasts to myotubes in a reversible manner and blocks the differentiation of myoblasts and myotubes in mammalian cells in culture. It is not a competitive inhibitor with respect to either ATP or substrate. It is hyperactive in inflammatory diseases and may reverse inflammation. Synonyms: JX-401; JX 401; JX401; 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine; [2-Methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]-methanone; N-(2-Methoxy-4-thiomethyl)benzoyl-4-benzylpiperidine. Grades: ≥98% by HPLC. CAS No. 349087-34-9. Molecular formula: C21H25NO2S. Mole weight: 355.49.
JY-2
JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 ?M. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 339103-05-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153347.
JYL1421
JYL1421 is a TRPV1 receptor antagonist. JYL1421 concentration-dependently (0.1-2 mM) inhibited capsaicin-evoked substance P, calcitonin gene-related peptide and somatostatin release from isolated tracheae. It also concentration-dependently decreased capsaicin-induced Ca(2+) accumulation in cultured trigeminal ganglion cells. Synonyms: 3-[ (4-Tert-butylphenyl) methyl]-1-[ (3-fluoro-4-methanesulfonamidophenyl) methyl]thiourea. Grades: ≥95%. CAS No. 401907-26-4. Molecular formula: C20H26FN3O2S2. Mole weight: 423.6.
JYN42346
JYN42346, also known as Complement factor D-IN-2, is an inhibitor of complement factor D. JYN42346 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. JYN42346 can be used for the research of autoimmune diseases. JYN42346 was first reported in patent WO2015130838A1 (compound 190). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Complement factor D-IN-2; JYN42346; JYN 42346; JYN-42346. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1903742-34-6. Molecular formula: C27H24BrN7O3. Mole weight: 574.44. Purity: >98%. IUPACName: (1R,3S,5R)-2-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-2-azabicyclo[3.1.0]hexane-3-carboxamide. Canonical SMILES: O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)[C@]5([H])C[C@]5([H])C1)NC6=NC(Br)=CC=C6. Product ID: ACM1903742346. Alfa Chemistry ISO 9001:2015 Certified.
JZL184
JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM. Synonyms: JZL184; JZL 184; JZL-184. Grades: >98%. CAS No. 1101854-58-3. Molecular formula: C27H24N2O9. Mole weight: 520.49.
JZL 184
JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1101854-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15249.
JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC 50 s of 2 and 4 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1210004-12-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15250.
JZL195
JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. IC50 values are 2 nM for MAGL and 4 nM for FAAH. JZL195 has been shown to inhibit endocannabinoid hydrolysis and elevate 2-AG and AEA levels in vivo. Synonyms: JZL195; JZL-195; JZL 195. Grades: >98%. CAS No. 1210004-12-8. Molecular formula: C24H23N3O5. Mole weight: 433.46.
JZL 195. Group: Biochemicals. Grades: Purified. CAS No. 1210004-12-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
JZP 361
JZP 361 is a reversible, potent and selective inhibitor of human recombinant MAGL (hMAGL) with IC50 value of 46 nM. It shows affinity for H1 receptors but shows no activity at cannabinoid receptors. It has MAGL-inhibitory and antihistaminergic and may be a novel dual-acting pharmacological tool. Synonyms: JZP-361; JZP 361; JZP361; [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-triazol-1-yl)methanone. Grades: ≥99% by HPLC. CAS No. 1680193-80-9. Molecular formula: C22H20ClN5O. Mole weight: 405.88.
JZP-430
JZP-430, a thiadiazol derivative, has been found to be an ABHD6 inhibitor that could probably be effective in obesity and type?II diabetes therapy. IC50: 44 nM. Synonyms: JZP-430; JZP 430; JZP430; 4-morpholino-1,2,5-thiadiazol-3-yl cyclooctyl(methyl)carbamate. Grades: 98%. CAS No. 1672691-74-5. Molecular formula: C16H26N4O3S. Mole weight: 354.47.