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| Product | Description | |
|---|---|---|
| LX2343 | LX2343 is an inhibitor of β-site amyloid protein cleaving enzyme 1 (BACE1/β-secretase) with IC50 = 11.43 μM. It also acts as a non-ATP competitive PI3K inhibitor (IC50 = 15.99 μM). LX2343 was shown to ameliorate the cognitive dysfunction of AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy. Synonyms: LX-2343; LX 2343; 2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide. Grades: ≥98%. CAS No. 333745-53-2. Molecular formula: C22H19ClN2O6S. Mole weight: 474.91. |  |
| LX-2761 | LX-2761 is a locally acting SGLT1 inhibitor that can delay intestinal glucose absorption in the body to improve blood sugar control. Synonyms: LX2761. Grades: ≥ 98 % by HPLC. CAS No. 1610954-97-6. Molecular formula: C32H47N3O6S. Mole weight: 601.8. | |
| LX-4211 | LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: LX4211; LX-4211; LX 4211; Sotagliflozin. Grades: >98%. CAS No. 1018899-04-1. Molecular formula: C21H25ClO5S. Mole weight: 424.94. | |
| LX7101 | LX7101 is a pyrrolopyrimidine-based, topically-delivered inhibitor of LIM domain kinase 2 (LIMK2), a kinase associated with the regulation of intraocular pressure. It is also a ROCK inhibitor used for the treatment of glaucoma. LX7101 acts by enhancing fl. Uses: Lx7101 is a lim domain kinase 2 (limk2) inhibitor which could be probably effective in the treatment of glaucoma. Synonyms: 3-(4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido)phenyl dimethylcarbamate hydrochloride. Grades: > 95%. CAS No. 1192189-69-7. Molecular formula: C23H30ClN7O3. Mole weight: 487.99. | |
| LX7101 hydrochloride | LX7101 is a dual inhibitor of LIM kinase (LIMK) and Rho-associated kinase (ROCK) with IC50 values of 32, 4.3, 69, and 32 nM for LIMK1, LIMK2, ROCK1 and ROCK2, respectively. It has been identified as a candidate for the treatment of ocular hypertension and associated glaucoma due to its high efficacy and good safety profile. Synonyms: LX7101 HCl; [3-[[4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carbonyl]amino]phenyl] N,N-dimethylcarbamate hydrochloride. Grades: ≥98%. Molecular formula: C23H29N7O3·HCl. Mole weight: 488. | |
| LXE408 | LXE408 is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 has an IC 50 of 0.04 μM for L. donovani proteasome and an EC 50 of 0.04 μM for L. donovani. LXE408 has a low propensity to cross the blood brain barrier. LXE408 has the potential for visceral leishmaniasis (VL) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799330-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-131350. |  |
| LXH254 | LXH254 is a pan-Raf inhibitor developed for the treatment of solid tumors. Uses: Antineoplastic agents. Synonyms: LXH-254; LXH 254; N-[3-[2-(2-Hydroxyethoxy)-6-morpholin-4-ylpyridin-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide. Grades: ≥98%. CAS No. 1800398-38-2. Molecular formula: C25H25F3N4O4. Mole weight: 502.49. | |
| LXR623 | WAY-252623 (LXR-623) is a highly selective and orally bioavailable synthetic modulator of LXR, which can reduces total serum cholesterol and LDL cholesterol and inhibits lesion growth in models of atherosclerosis. IC50 values= 24 and 179 nM (for LXRβ and LXRα, respectively). Uses: A novel and potent lxr (liverx receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis ic50 values= 24 and 179 nm (for lxrβ and lxrα, respectively). Synonyms: 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole; 2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole; LXR 623; LXR-623; LXR623; WAY 252623; WAY-252623; WAY252623. Grades: ≥ 98.0%. CAS No. 875787-07-8. Molecular formula: C21H12ClF5N2. Mole weight: 422.78. | |
| LXS196 | LXS196 is a potent and orally active protein kinase C (PKC) inhibitor under clinical trials for the treatment of uveal melanoma, the most common cancer of the eye in adults. Synonyms: 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide; LXS 196; LXS-196. CAS No. 1874276-76-2. Molecular formula: C22H23F3N8O. Mole weight: 472.47. | |
| L-Xylonic acid-1,4-lactone | L-Xylonic acid-1,4-lactone is an extraordinary biomedical compound, emerging as a promising solution for studying diverse recalcitrant malignancies and neurodegenerative maladies. Derived proficiently from xylose, it showcases remarkable antioxidant attributes and assumes a pivotal stance in intracellular metabolism. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| L-Xylosamine | L-Xylosamine is a bioactive molecule extensively employed in the biomedical realm assuming a fundamental role when studying a plethora of ailments intertwined with glycosaminoglycan metabolism. Its pivotal function as a precursor augments the biosynthesis of heparan sulfate is a vital constituent within the extracellular matrix. Molecular formula: C5H11NO4. Mole weight: 149.15. | |
| L-Xylose | L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L-(-)-Xylose. CAS No. 609-06-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-78139. | |
| L-xylose 1-dehydrogenase | Also oxidizes D-arabinose and D-lyxose. Group: Enzymes. Synonyms: L-xylose dehydrogenase; NADPH-xylose reductase. Enzyme Commission Number: EC 1.1.1.113. CAS No. 37250-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0016; L-xylose 1-dehydrogenase; EC 1.1.1.113; 37250-44-5; L-xylose dehydrogenase; NADPH-xylose reductase. Cat No: EXWM-0016. |  |
| L-Xylose-BSA | | |
| L-xylulokinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:L-xylulose 5-phosphotransferase. This enzyme is also called L-xylulokinase (phosphorylating). This enzyme participates in pentose and glucuronate interconversions and ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: L-xylulokinase (phosphorylating). Enzyme Commission Number: EC 2.7.1.53. CAS No. 37278-01-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3084; L-xylulokinase; EC 2.7.1.53; 37278-01-6; L-xylulokinase (phosphorylating). Cat No: EXWM-3084. | |
| L-Xylulose | L-Xylulose is an endogenous metabolite present in Blood, Cerebrospinal_Fluid and Urine that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 527-50-4. Pack Sizes: 2.5 mg (1 M * 16.65 μL in Water). Product ID: HY-113317. | |
| L-Xylulose | L-Xylulose, an organic sugar alcohol, finds significant utility within the dynamic biomedicine sector as a crucial carbohydrate source and an intermediary compound in the synthesis of pharmaceuticals and biochemicals. Synonyms: L-threo-Pentulose; L-threo-2-Pentulose; L-threo-pent-2-ulose. CAS No. 527-50-4. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| L-Xylulose - Aqueous solution | Cas No. 527-50-4. | |
| L-xylulose reductase | Dicarbonyl/L-xylulose reductase, also known as carbonyl reductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17. DCSR catalyzes the reduction of several L-xylylose as well as a number of pentoses, tetroses, trioses, alpha-dicarbonyl compounds. The enzyme is involved in carbohydrate metabolism, glucose metabolism, the uronate cycle and may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol. Group: Enzymes. Synonyms: xylitol dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.10. CAS No. 9028-17-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0002; L-xylulose reductase; EC 1.1.1.10; 9028-17-5; xylitol dehydrogenase (ambiguous). Cat No: EXWM-0002. | |
| LY1 | LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PL pro and M pro with K d values of 1.5 μM and 2.3 μM for M pro C145A protein and PL pro C111A protein, respectively. LY1 potent against the viral proteases, with IC 50 s of 0.12 μM and 0.99 μM against M pro and PL pro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2883813-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152101. | |
| LY 106737 | LY 106737 is phenylpiperidine opioid receptor antagonist, but no detailed information has been published yet. Synonyms: LY 106737; LY-106737; LY106737; cis-(+-)-3-(3,4-dimethyl-1-(2-phenylethyl)-4-piperidinyl)-Phenol. Grades: 98%. CAS No. 82970-72-7. Molecular formula: C21-H27-N-O. Mole weight: 309.45. | |
| LY-113174 | LY-113174 is a novel class of nonsteroidal aromatase inhibitor. It may prove useful in the treatment of estrogen-dependent diseases. Uses: Ly-113174 may prove useful in the treatment of estrogen-dependent diseases. Synonyms: 5H-Indeno[1,2-d]pyrimidine,8-chloro-5-(4-chlorophenyl)-;8-Chloro-5-(4-chlorophenyl)-5H-indeno[1,2-d]pyrimidine; LY 113174; LY113174; LY-113174. Grades: >98%. CAS No. 112959-07-6. Molecular formula: C17H10Cl2N2. Mole weight: 313.18. | |
| LY 117413 | LY 117413 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 117413; LY117413; LY-117413; Lilly 117413. 4-(3-hydroxyphenyl)-3,4-dimethyl-alpha-phenyl- 1-Piperidinepropanol. Grades: 98%. CAS No. 82970-70-5. Molecular formula: C22H29NO2. Mole weight: 339.48. | |
| LY 123502 | LY 123502 is an opioid agonist, but no detailed information has been published yet. Synonyms: LY 123502; LY-123502; LY123502; L-Tyrosyl-D-alanylglycyl-4-fluoro-L-phenylalanyl-L-2-phenylglycinamide monoacetate (salt). Grades: 98%. CAS No. 79561-42-5. Molecular formula: C33H39FN6O8. Mole weight: 666.70. | |
| LY 125180 | LY 125180 is a serotonin antagonist.It can effect on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo. Synonyms: LY 125180; LY-125180; LY125180. N,N-dimethyl-alpha-(2-(4-methylphenoxy)ethyl)-Benzenemethanamine hydrochloride. Grades: 98%. CAS No. 74515-39-2. Molecular formula: C18H24ClNO. Mole weight: 305.85. | |
| LY 134046 | LY 134046 is a centrally active PNMT (phenylethanolamine-N-methyltransferase) inhibitor. It has cardiovascular effects in spontaneously hypertensive rats. Synonyms: LY 134046; LY134046; LY-134046; Lilly 134046; 8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine. Grades: 98%. CAS No. 71274-97-0. Molecular formula: C10H11Cl2N. Mole weight: 216.11. | |
| LY 135114 | LY 135114 is a metabolite of LY 195448. LY195448 is a Alpha adrenergic receptor originate by Eli Lilly. But clinical trials for the treatment of cancer had been discontinued. Uses: Ly 135114 is a metabolite of ly 195448. Synonyms: LY 135114; LY135114; LY-135114. 3-[3-[[2-hydroxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methylbutyl]benzamide. Grades: 98%. CAS No. 126254-82-8. Molecular formula: C20H26N2O3. Mole weight: 342.43. | |
| LY 135305 | LY 135305 is a bio-active molecular under the development of Eli Lilly. It can inhibit spontaneous lung metastasis in a dose-dependent manner. Uses: Tumor. Synonyms: LY 135305; LY135305; LY-135305. beta-phenyl-1-Naphthalenepropanamine hydrochloride. Grades: 98%. CAS No. 123199-75-7. Molecular formula: C19H20ClN. Mole weight: 297.82. | |
| LY 137150 | LY 137150 is a bio-active chemical, but no detailed information has been published yet. Synonyms: LY 137150; LY137150; LY-137150. 2-(2-Methoxy-4-(methylthiol)phenyl)-1H-imidazo-(4,5-c)pyridine hydrochloride. Grades: 98%. CAS No. 86315-69-7. Molecular formula: C14H14ClN3OS. Mole weight: 307.80. | |
| LY 140091 | LY 140091 is a bio-active chemical, but no detailed information has been published yet. Synonyms: LY 140091; LY140091; LY-140091. (Z)-3-((5-methoxy-3-oxo-2(3H)-benzofuranylidene)methyl)-Benzoic acid. Grades: 98%. CAS No. 74814-56-5. Molecular formula: C17H12O5. Mole weight: 296.27. | |
| LY-150310 | LY-150310 is a histamine H1-receptor antagonist. It could alter prostanoid concentrations in vitro and in vivo. Uses: Ly-150310 could alter prostanoid concentrations. Synonyms: LY 150310; LY-150310; LY150310; 1H-Imidazole, 1-(1,2,3,4-tetrahydro-1-naphthalenyl)-;LY150310;1-(1,2,3,4-tetrahydronaphthalen-1-yl)imidazole. Grades: >98 %. CAS No. 103294-47-9. Molecular formula: C13H14N2. Mole weight: 198.27. | |
| LY 156735 | This active molecular is high affinity nonselective melatonin receptors MT1 and MT2 agonist which is under development for the treatment of insomnia and other sleep disorders. Its agonist action on MT1 and MT2 receptors in the suprachiasmatic nucleus in the brain enables its action as a chronobiotic. The action of LY 156735 on MT1 and MT2 receptors promots sleeping because melatonin's effects at these same receptors is linked with maintenance of normal-sleep wake cycle. The EC50 value of LY 156735 is 0.0479nM, compared to 0.063nM for melatonin. In May 2004, LY 156735 had received orphan drug status for the treatment of circadian sleep disorders in totally blind individuals in the US. In Nov 2005, data which was presented at the 18th Annual Congress of the European College of Neuropsychopharmacology had been added to the adverse events and Anxiety disorders therapeutic trials sections. Uses: The treatment of insomnia and other sleep disorders. Synonyms: LY 156735; LY156735; LY-156735; TIK-301; TIK 301; TIK301; N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide. Grades: 98%. CAS No. 118702-11-7. Molecular formula: C14H17ClN2O2. Mole weight: 280.75. | |
| LY 163252 | LY 163252 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 163252; LY 163252; LY 163252. 2-(2-methoxy-4-(methylsulfonyl)phenyl)-1H-Imidazo(4,5-c)pyridine monohydrochloride. Grades: 98%. CAS No. 87359-44-2. Molecular formula: C14H14ClN3O3S. Mole weight: 339.80. | |
| LY 164929 | This active molecular is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site. Synonyms: LY 164929; LY164929; LY-164929. (S)-N-((R)-1-(2-(((S)-1-(dimethylamino)-3-phenylpropan-2-yl)(ethyl)amino)acetamido)-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)-2-(methylamino)propanamide. Grades: 98%. CAS No. 113573-18-5. Molecular formula: C28H41N5O4. Mole weight: 511.66. | |
| LY171883 | LY171883 is an orally available leukotriene D4 receptor antagonist. Uses: Leukotriene antagonists. Synonyms: LY-171883; LY 171883; Tomelukast; 1-[2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl]ethanone. Grades: ≥98%. CAS No. 88107-10-2. Molecular formula: C16H22N4O3. Mole weight: 318.4. | |
| LY 173013 | LY173013 is an antibacterial agent with bicyclic pyrazolidinones containing a novel aza-γ-lactam ring structure. The properties of this compound appear to be related to those of β-lactam antibiotics, because both classes of compounds have common binding molecules such as β-lactamases and penicillin-binding proteins. Uses: Antibacterial agent. Synonyms: LY 173013; LY-173013; LY173013. 2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-methoxycarbonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 126165-78-4. Molecular formula: C15H16N6O7S. Mole weight: 424.39. | |
| Ly 178002 | Heterocyclic Organic Compound. Alternative Names: LY 178002; 5-[[3, 5-Bis (1, 1-dimethylethyl) -4-hydroxyphenyl]methylene]thiazolidin-4-one. CAS No. 107889-32-7. Catalog: ACM107889327. |  |
| LY-178002 | LY-178002 is a phospholipase A2 inhibitor. It also inhibits leukotriene B4 production. Synonyms: LY 178002; LY178002; LY-178002. 5-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]thiazolidin-4-one;5-(3,5-Bis(tert-butyl)-4-hydroxyphenyl)methylene-4-thiazolidinone;4-Thiazolidinone, 5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-. Grades: >98%. CAS No. 107889-32-7. Molecular formula: C18H25NO2S. Mole weight: 319.46. | |
| LY 181984 | LY 181984 is an antitumor sulfonylurea. Uses: Antitumor. Synonyms: LY 181984; LY-181984; LY181984; MPCU. N-(((4-chlorophenyl)amino)carbonyl)-4-methyl-Benzenesulfonamide;1-(4-chlorophenyl)-3-(4-methylphenyl)sulfonylurea. Grades: ≥98%. CAS No. 3955-50-8. Molecular formula: C14H13ClN2O3S. Mole weight: 324.78. | |
| LY-183648 | LY-183648 has antiestrogenic activity. It inhibited PAIII metastasis to the gluteal and iliac lymph nodes. Uses: Ly-183648 has antiestrogenic activity. Synonyms: LY 183648; LY183648; LY-183648. 5-[Bis(4-chlorophenyl)-imidazol-1-ylmethyl]pyrimidine; LY183648; Pyrimidine, 5-(bis(4-chlorophenyl)-1H-imidazol-1-ylmethyl)-. Grades: >98 %. CAS No. 102993-90-8. Molecular formula: C20H14Cl2N4. Mole weight: 381.26. | |
| LY-186126 | LY 186126 is a potent cGI-PDE inhibitor. It exhibit reversible and high affinity binding to a single class of SaR binding sites. Synonyms: LY 186126; LY186126; LY-186126. 1,3-Dihydro-1,3,3-trimethyl-5-[(1,4,5,6-tetrahydro-4-methyl-6-oxopyridazin)-3-yl]-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-1,3,3-trimethyl-5-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-;1,3,3-Trimethyl-6-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)indol-2-one. Grades: >98 %. CAS No. 100644-00-6. Molecular formula: C16H19N3O2. Mole weight: 285.34. | |
| LY 186564 | LY 186564 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 186564; LY186564; LY-186564. 3-(((dipropylamino)carbonyl)oxy)- Estra-1,3,5(10)-trein-17-one. Grades: 98%. CAS No. 143982-31-4. Molecular formula: C25H35NO3. Mole weight: 397.55. | |
| LY 186826 | LY 186826 is an antibacterial agent with bicyclic pyrazolidinones containing a novel aza-γ-lactam ring structure. The properties of this compound appear to be related to those of β-lactam antibiotics, because both classes of compounds have common binding molecules such as β-lactamases and penicillin-binding proteins. Uses: Antibacterial agent. Synonyms: LY 186826; LY186826; LY-186826. AC1NUT6W; CHEMBL436143; HE187334; 6-acetyl-2-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 126165-79-5. Molecular formula: C15H16N6O6S. Mole weight: 408.39. | |
| LY 188011 | LY 188011 Inhibitor. Uses: Scientific use. Product Category: T6069. CAS No. 122111-03-9. |  |
| LY 189332 | LY 189332 is a bio-active molecular under the development of Eli Lilly as an antimetastatic drug. Uses: Antimetastatic drug. Synonyms: LY 189332; LY-189332; LY189332. N-(4-fluorophenyl)-4,4''-dimethoxy-(1,1':2',1''-Terphenyl)-4'-amine. Grades: 98%. CAS No. 123215-05-4. Molecular formula: C26H22FNO2. Mole weight: 399.46. | |
| LY-190388 | LY-190388 is an μ receptor agonist. It is a penicillamine-containing enkephalin analog and has analgesia effect. Uses: Ly-190388 has analgesia effect. Synonyms: LY 190388; LY190388; LY-190388; H-Tyr-pen-gly-phe-val-OH;Tyr-penicillamine-gly-phe-val;(2R)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-[2-[[(2S)-2-amino-3-methyl-3-sulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoic acid;LY190388;D-Valine, N-(N-(N-(3-mercapto-N-L-tyrosyl-D-valyl)glycyl)-L-phenylalanyl)-. Grades: >98%. CAS No. 105496-35-3. Molecular formula: C30H41N5O7S. Mole weight: 615.74. | |
| LY 191704 | LY 191704, a hexahydrobenzoquinolin derivative, has been found to be a human type I steroid 5alpha-reductase inhibitor that could be probably effective in the treatment of Alopecia and Benign prostatic hyperplasia. It was developed by Eli Lilly and had no development reports since 2001. Uses: 5-alpha reductase inhibitors. Synonyms: LY191704; LY-191704; 8-Chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2H)-one. Grades: 98%. CAS No. 146117-78-4. Molecular formula: C14H16ClNO. Mole weight: 249.74. | |
| LY 193239 | This bio-active molecular is a cell wall inhibitor as a antibacterial agent. LY 193239 has a lactam pyrazolidinone structure. Clinical trials for Bacterial infections were discontinued. Uses: Antibacterial. Synonyms: LY 193239; LY193239; LY-193239. (2S)-2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-methylsulfonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 124986-46-5. Molecular formula: C14H16N6O7S2. Mole weight: 444.44. | |
| LY-195448 | LY-195448 is a phenethanolamine. It blocks cells at metaphase. It has shown anti-tumour activity. Uses: Ly-195448 has shown anti-tumour activity. Synonyms: LY 195448; LY195448; LY-195448; UNII-BR0DFE3GF6. (R)-4-(3-((2-Hydroxy-2-phenethyl)amino)-3-methylbutyl)benzamide monohydrochloride;4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide hydrochloride. Grades: >98%. CAS No. 111112-18-6. Molecular formula: C20H27ClN2O2. Mole weight: 362.90. | |
| LY-201409 | LY-201409 is a potent benzamide anticonvulsant. It antagonized maximal electroshock (MES)-induced seizures with ED50 values of 16.2 and 4.2 mg/kg after oral administration to mice and rats, respectively. Uses: Ly-201409 has anticonvulsant effect. Synonyms: LY 201409; LY201409; LY-201409. 4-Amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide;Benzamide, 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethyl-. Grades: >98%. CAS No. 109306-94-7. Molecular formula: C17H20N2O. Mole weight: 268.36. | |
| LY 203647 | LY 203647 is a a leukotriene D4 and E4 receptor antagonist with a tetrazole nucleus structure originated by Eli Lilly. No development for treatment of Ischaemic heart disorders by LY 203647 has been reported yet. Uses: Ischaemic heart disorders. Synonyms: LY 203647; LY203647; LY-203647; 1-(2-hydroxy-3-propyl-4-(4-(2-(4-(1H-tetrazol-5-yl)butyl)-2H-tetrazol-5-yl)butoxy)phenyl)-Ethanone. Grades: 98%. CAS No. 122009-61-4. Molecular formula: C21H30N8O3. Mole weight: 442.52. | |
| LY 206130 | This active molecular is a serotonin 5-HT1A antagonist. LY 206130 (3.0 mg/kg, s.c.) alone significantly increased norepinephrine level by 60%, dopamine levels by 34% without affecting 5-HT levels. Synonyms: LY 206130; LY-206130; LY206130. CHEMBL396185;AC1L3YFA; SCHEMBL7287084;1-(cyclohexylamino)-3-(1H-indol-4-yloxy)propan-2-ol. Grades: 98%. CAS No. 127414-58-8. Molecular formula: C17H24N2O2. Mole weight: 288.39. | |
| LY-207702 | LY-207702 is a difluorinated purine nucleoside. It exhibits antitumor activity in preclinical models. It was developed by Eli Lilly & Co. Uses: Ly-207702 exhibits antitumor activity. Synonyms: LY 207702; LY-207702; LY207702. 2',2'-Difluorodeoxyribofuranosyl-2,6-diaminopurine;5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9-(2-Deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-9H-purine-2,6-diamine;(2R,3R)-5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9H-Purine-2,6-diamine, 9-(2-deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-. Grades: >98 %. CAS No. 103828-81-5. Molecular formula: C10H12F2N6O3. Mole weight: 302.24. | |
| LY 2087101 | LY 2087101. Group: Biochemicals. Grades: Purified. CAS No. 913186-74-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| LY 2087101 | LY 2087101 is a selective positive allosteric potentiator of α7 and α4β2 nicotinic acetylcholine receptors. Synonyms: LY2087101; LY 2087101; LY-2087101; [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone. Grades: ≥98% by HPLC. CAS No. 913186-74-0. Molecular formula: C15H11FN2OS2. Mole weight: 318.39. | |
| LY2090314 | LY2090314 is a potent GSK3 inhibitor with antiproliferative activity. It was shown to promote differentiation of intestinal progenitor cells from human iPSCs. Synonyms: LY-2090314; 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione. Grades: >98%. CAS No. 603288-22-8. Molecular formula: C28H25FN6O3. Mole weight: 512.545. | |
| LY 210073 | LY 210073, an oxoxanthene derivative, has been found to be a LTB4 receptor antagonist that could probably be effective against inflammation and rheumatic disorders. Synonyms: 9H-Xanthene-4-propanoicacid, 7-carboxy-3-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-9-oxo-; ACMC-20n5ed; CTK0H7653; CTK8H0111; LY 210073; LY-210073; LY210073. Grades: 98%. CAS No. 148291-65-0. Molecular formula: C30H28O8. Mole weight: 516.55. | |
| LY2109761 | LY2109761 is a novel inhibitor of TGF-β receptor type I/type II kinases (IC50 = 69 nM), displaying antitumor activity. In vivo study demonstrated that LY2109761, in combination with gemcitabine, significantly reduced the tumor burden, prolonged survival, and reduced spontaneous abdominal metastases. Synonyms: LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine. Grades: >98%. CAS No. 700874-71-1. Molecular formula: C26H27N5O2. Mole weight: 441.52. | |
| LY 2109761 | LY 2109761. Group: Biochemicals. Alternative Names: 4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]-quinoline. Grades: Highly Purified. CAS No. 700874-71-1. Pack Sizes: 5mg. Molecular Formula: C26H27N5O2, Molecular Weight: 441.52. US Biological Life Sciences. | Worldwide |
| LY2119620 | LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. Synonyms: LY2119620; LY 2119620; LY-2119620. Grades: >98%. CAS No. 886047-22-9. Molecular formula: C19H24ClN5O3S. Mole weight: 437.94. | |
| LY 213024 | LY 213024 is a potent leukotriene B4 receptor antagonist. Agents which block the production of the leukotrienes have shown reduction of infarct size in animal models of myocardial infarction. Uses: Myocardial infarction. Synonyms: LY 213024; LY213024; LY-213024; 3-[3-(2-carboxyethyl)-4-decoxybenzoyl]benzoic acid. Grades: 98%. CAS No. 117423-95-7. Molecular formula: C27H34O6. Mole weight: 454.56. | |
| LY2140023 | LY2140023 is a prodrug of LY-404039 and a novel metabotropic glutamate 2/3 receptor agonist peptide prodrug. lt is currently in clinical development as a potential new treatment for schizophrenia. Uses: Ly2140023 was used for the treatment of post-traumatic stress disorder and for the treatment of schizophrenia. Synonyms: Pomaglumetad methionil; LY-2140023; LY 2140023. Grades: 98%. CAS No. 635318-55-7. Molecular formula: C12H18N2O7S2. Mole weight: 366.40. | |
| LY2157299 (LY 2157299, LY-2157299, Galunisertib) | LY2157299 (LY 2157299, LY-2157299, Galunisertib). Group: Biochemicals. Alternative Names: 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grades: Highly Purified. CAS No. 700874-72-2. Pack Sizes: 5mg, 50mg. Molecular Formula: C22 H19 N5 , Molecular Weight: 369.4. US Biological Life Sciences. | Worldwide |
| LY 215840 | LY 215840. Group: Biochemicals. Grades: Purified. CAS No. 137328-52-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY 215840 | LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion and 5-HT-induced cAMP formation. LY 215840 has anti-hypertensive and muscle relaxant effects in animal models. No development was reported for the treatment of Thrombosis and Migraine. Uses: Migraine; thrombosis. Synonyms: LY 215840; LY-215840; LY215840. (6aR,9R)-N-[(1S,2R)-2-hydroxycyclopentyl]-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxamide. Grades: >98 %. CAS No. 137328-52-0. Molecular formula: C24H33N3O2. Mole weight: 395.55. | |
| LY 215890 | LY 215890 has been found to have probable antibiotic activity. Synonyms: LY 215890; LY-215890; LY215890. 7-(((2-Amino-4-thiazolyl)hydroximinoacetyl)amino)-3-chloro-1-carba-1-dethia-3-cephem-4-carboxylic acid. Grades: 98%. CAS No. 153502-35-3. Molecular formula: C13H12ClN5O5S. Mole weight: 385.78. | |
| LY-215891 | LY-215891 shows potent Gram-(+) and Gram-(-) antibacterial activity. Uses: Ly-215891 shows potent gram-(+) and gram-(-) antibacterial activity. Synonyms: LY 215891; LY215891; 7-(((2-Aminothiazol-4-yl)hydroximinoacetyl)amino)-3-chloro-3-cephem-4-carboxylic acid. Grades: 98%. CAS No. 68403-79-2. Molecular formula: C12H10ClN5O5S2. Mole weight: 403.81. | |
| LY2183240 | LY2183240 is a novel and highly potent blocker of anandamide uptake. It inhibits fatty acid amide hydrolase (FAAH) activity. It increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain. Synonyms: LY2183240; LY-2183240; LY 2183240. Grades: >98%. CAS No. 874902-19-9. Molecular formula: C17H17N5O. Mole weight: 307.35. | |
| LY2183240 2'-isomer | LY2183240 2'-isomer is a 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and cellular reuptake. LY2183240 2'-isomer exhibits less potent activity than LY2183240. Synonyms: 5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide; 5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide. Grades: ≥98%. CAS No. 1010096-65-7. Molecular formula: C17H17N5O. Mole weight: 307.4. | |
| LY 219057 | LY 219057, a phenylpyrazolidine derivative, has been found to be a CCK receptor antagonist that could probably be useful in gastrointestinal disorder studies. Synonyms: LY 219057; LY-219057; CHEMBL353189; N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxo-4,5-diphenylpyrazolidine-1-carbothioamide. Grades: 98%. CAS No. 150351-93-2. Molecular formula: C23H17ClF3N3OS. Mole weight: 475.91. | |
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