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Product
NS1209 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS-1209 NS-1209, an AMPA/GluR5 receptor antagonist, is a antiepileptic drug candidate currently under clinical trials. Synonyms: 2-[[5-[4-(dimethylsulfamoyl)phenyl]-8-methyl-2-oxo-7,9-dihydro-6H-pyrrolo[3,2-h]isoquinolin-3-yl]amino]oxy-4-hydroxybutanoic acid; NS-1209; NS 1209; NS1209; 245063-59-6; SPD-502; SPD502; SPD 502. Grades: >98%. CAS No. 245063-59-6. Molecular formula: C24H28N4O7S. Mole weight: 516.57. BOC Sciences 10
NS 1619 NS 1619, a benzimidazalone derivative, activates BKca channels in a number of tissues. However, the effect of NS 1619 was dependent upon the presence of Ca 2+ ions at the intracellular surface, for at free Ca2+ ion concentrations of 0.1/zM and below (a ra. Synonyms: 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-oneNS 1619; NS1619153587-01-0NS-16191-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-oneCHEMBL384903. Grades: >98 %. CAS No. 153587-01-0. Molecular formula: C15H8F6N2O2. Mole weight: 362.23. BOC Sciences 10
NS 1619 powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 1619 NS 1619. Group: Biochemicals. Grades: Purified. CAS No. 153587-01-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
NS-1619 NS-1619 is an opener of large conductance Ca 2+ -activated K + (BK) channel. NS-1619 is a highly effective relaxant with an EC 50 of about 10 - 30 μM in several smooth muscles of blood vessels and other tissues [1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153587-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12496. MedChemExpress MCE
NS1643 NS1643 is a partial agonist of human ether-a-go-go-related gene ( hERG ) K + channels with an EC 50 of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 448895-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16916. MedChemExpress MCE
NS1643 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 1643 NS 1643 is human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM). Uses: Kv11.1 channel activator. Synonyms: NS-1643; NS 1643; NS1643. 1,3-Bis(2-hydroxy-5-trifluoromethylphenyl)urea;N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea. Grades: ≥98 %. CAS No. 448895-37-2. Molecular formula: C15H10F6N2O3. Mole weight: 380.06. BOC Sciences 10
NS 1643 NS 1643. Group: Biochemicals. Alternative Names: 1, 3-Bis (2-hydroxy-5-trifluoromethylphenyl) urea; N, N'-bis[2-hydroxy-5- (trifluoromethyl) phenyl]urea. Grades: Highly Purified. CAS No. 448895-37-2. Pack Sizes: 10mg. Molecular Formula: C15H10F6N2O2S, Molecular Weight: 396.31. US Biological Life Sciences. USBiological 3
Worldwide
NS 1738 NS 1738 is an allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs). It shows cognitive-enhancing properties in vivo. Synonyms: NS1738; NS 1738; NS-1738; N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 501684-93-1. Molecular formula: C14H9Cl2F3N2O2. Mole weight: 365.13. BOC Sciences 10
NS 1738 NS 1738. Group: Biochemicals. Grades: Purified. CAS No. 501684-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS1738 (1- (5-chloro-2-hydroxyphenyl) -3- (2-chloro-5- (trifluoromethyl) phenyl) urea, a7 nAChR Positive Allosteric Modulator, NS1738, NS 1738, NS-1738) A biarylurea derivative that acts as a selective positive allosteric modulator selective for alpha7 nicotinic acetylcholine receptors (alpha7 nAChR) without substantial activity for alpha4beta2, alpha3beta3 and alpha1-containing receptors. Exhibits cognitive enhancing effects in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 501684-93-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
NS 19504 NS 19504. Group: Biochemicals. Grades: Purified. CAS No. 327062-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS 19504 NS 19504 is an activator of large-conductance Ca2+-activated potassium channels. It has relaxing effects on bladder smooth muscle. Synonyms: NS 19504; NS19504; NS-19504; 5-[(4-Bromophenyl)methyl]-2-thiazolamine. Grades: ≥99% by HPLC. CAS No. 327062-46-4. Molecular formula: C10H9BrN2S. Mole weight: 269.16. BOC Sciences 10
N-[(S)-1-Carbethoxybutyl]-(S)-alanine Perindopril intermediate. Group: Biochemicals. Alternative Names: (S)-N-(1-Carboxyethyl)-L-norvaline 1-Ethyl Ester; N-((S)-Ethoxycarbonyl-1-butyl)-(S)-alanine. Grades: Highly Purified. CAS No. 82834-12-6. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
Worldwide
N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (S)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 151252-80-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences. USBiological 8
Worldwide
NS 2028 solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 2028 NS 2028. Group: Biochemicals. Grades: Purified. CAS No. 204326-43-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS 2028 S-2028 is a soluble guanylyl cyclase inhibitor. It can inhibit purified bovine lung guanylyl cyclase with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes. Synonyms: NS 2028; NS-2028; NS2028; 8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one. Grades: ≥98% by HPLC. CAS No. 204326-43-2. Molecular formula: C9H5BrN2O3. Mole weight: 269.05. BOC Sciences 9
NS-2028 NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity[1]. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase with IC50 values of 17 nM and 20 nM[1]. NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells with an IC50 of 30 nM[1]. NS-2028 is commonly used in the research of nitric oxide signaling pathways, it inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 ?M)[1]. NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 204326-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12379. MedChemExpress MCE
NS-2214 NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease. Synonyms: Brasofensine sulfate; BMS 204756; BMS-204756; NS 2214; NS2214; NS-2214; (E)-1-[(1R,3S,4R,5R)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-N-methoxymethanimine;sulfuric acid. Grades: 98%. CAS No. 171655-92-8. Molecular formula: C16H22Cl2N2O5S. Mole weight: 425.32. BOC Sciences 9
NS-2359 NS-2359, a serotonin-norepinephrine-dopamine reuptake inhibitor, may be able to reduce cocaine withdrawal symptoms, reduce cocaine craving and reduce cocaine-induced euphoria. Synonyms: (1S,3S,4R,5R)-3-(3,4-dichlorophenyl)-4-(methoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane; GSK 372475; GSK-372475; GSK372475; NS 2359; NS2359; NS-2359. Grades: >98%. CAS No. 195875-68-4. Molecular formula: C16H21Cl2NO. Mole weight: 558.675. BOC Sciences 10
NS2B/NS3-IN-2 NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3010940-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144612. MedChemExpress MCE
N- [S- (2-Pyridylthio) cysteaminyl] ethylenediamine-N, N, N', N'-tetraacetic Acid, Monoamide, Technical grade 90% A useful ligand for incorporation of EDTA-metal complexes into proteins particularly for investigating orientation of DNA binding proteins. Group: Biochemicals. Grades: Purified. CAS No. 143541-95-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide. Group: Biochemicals. Alternative Names: Boc-aoa-NH-(CH2)2-S-S-pyr. Grades: Highly Purified. CAS No. 887407-46-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4S2. US Biological Life Sciences. USBiological 8
Worldwide
N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide (Boc-Aoa-NH-(CH2)2-S-S-Pyr) A useful disulfide cleavable linking reagent. Group: Biochemicals. Alternative Names: Boc-Aoa-NH-(CH2)2-S-S-Pyr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
NS-304 NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Synonyms: Selexipag; NS304; NS 304; ACT-293987; ACT293987; ACT 293987; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide. Grades: ≥95%. CAS No. 475086-01-2. Molecular formula: C26H32N4O4S. Mole weight: 496.6. BOC Sciences 8
NS 30678 hydrochloride NS 30678 hydrochloride is a dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki = 9.7 nM, IC50 = 7 nM, in HEK-hD2L-Gαqi5 cells). Synonyms: NS 30678 hydrochloride; NS30678 hydrochloride; NS-30678 hydrochloride. Grades: 99%. CAS No. 1193707-19-5. Molecular formula: C12H16ClNO4S.HCl. Mole weight: 342.24. BOC Sciences 10
NS309 NS309 is a small- and intermediate- conductance Ca2+-activated K+ channels of SK and IK types whereas exhibits no activity at BK channels. Synonyms: 6,7-dichloro-3-(hydroxyamino)indol-2-one 6,7-dichloro-1H-indole-2,3-dione 3-oxime NS 309 NS-309 NS309 cpd. Grades: >98 %. CAS No. 18711-16-5. Molecular formula: C8H4Cl2N2O2. Mole weight: 231.04. BOC Sciences 10
NS309 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 309 NS 309. Group: Biochemicals. Grades: Purified. CAS No. 18711-16-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS 3623 NS 3623. Group: Biochemicals. Alternative Names: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2- (2H-tetrazol-5-yl) phenyl]-N'-[3- (trifluoromethyl) phenyl]-urea. Grades: Highly Purified. CAS No. 343630-41-1. Pack Sizes: 10mg. Molecular Formula: C15H10BrF3N6O, Molecular Weight: 427.18. US Biological Life Sciences. USBiological 3
Worldwide
NS 3623 NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. It can activate the IKr and Ito currents and display antiarrhythmic activity. Synonyms: NS3623; NS 3623; NS-3623. N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea. Grades: ≥99% by HPLC. CAS No. 343630-41-1. Molecular formula: C15H10BrF3N6O. Mole weight: 427.18. BOC Sciences 10
NS3694 ?98%, powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 3694 NS 3694 is an apoptosis inhibitor that inhibits the formation of the apoptosome Apaf-1 via blocking the activation of the initiator caspase 9. It does not affect apoptosome-independent caspase activation or enzymatic activity of caspases. Synonyms: NS 3694; NS3694; NS-3694; Apoptosis Inhibitor II; 4-chloro-2-[[3- (trifluoromethyl) phenyl]carbamoylamino]benzoic acid. Grades: 99%. CAS No. 426834-38-0. Molecular formula: C15H10ClF3N2O3. Mole weight: 358.7. BOC Sciences 10
NS3728 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS3763 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
NS 3763 NS 3763. Group: Biochemicals. Grades: Purified. CAS No. 70553-45-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS 3763 NS 3763 is a non-competitive kainate receptor antagonist of GLUK5 subunit-containing receptors (IC50 = 1.6 mM)) without disrupting GLU(K6) subtype (IC50 > 30 microM). Besides, NS 3763 has minimal activity at AMPA and NMDA receptors (IC50 > 30 μM). Synonyms: NS3763; NS 3763; NS-3763. 1,?3-Benzenedicarboxylic acid, 4,?6-bis(benzoylamino)?-; 4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid; 4,6-Dibenzamidoisophthalic acid. CAS No. 70553-45-6. Molecular formula: C22H16N2O6. Mole weight: 404.37. BOC Sciences 9
NS383 NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC 50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 309711-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131879. MedChemExpress MCE
NS3861 NS3861 is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121A. MedChemExpress MCE
NS3861 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 3861 NS 3861 is an α3β2 full agonist with EC50 of 1.6 μM. It is also an α3β4 partial agonist with EC50 of 1 μM. Synonyms: NS3861; NS-3861; NS 3861; 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene fumarate. Grades: ≥98% by HPLC. CAS No. 216853-60-0. Molecular formula: C12H14BrNS.C4H4O4. Mole weight: 400.29. BOC Sciences 10
NS3861 fumarate NS3861 fumarate is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-60-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121. MedChemExpress MCE
NS 398 NS 398 is a selective COX-2 inhibitor. Uses: Cyclooxygenase inhibitors. Synonyms: NS-398; NS 398; NS398. N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide. CAS No. 123653-11-2. Molecular formula: C13H18N2O5S. Mole weight: 314.36. BOC Sciences 11
NS 398 NS 398. Group: Biochemicals. Grades: Purified. CAS No. 123653-11-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS-398 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS-398 NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 ( COX-2 ) activity, with an IC 50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913. MedChemExpress MCE
NS-398 - CAS 123653-11-2 A cell-permeable selective inhibitor of COX-2 in vitro. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS-398 (NS398, NS 398) NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences. USBiological 9
Worldwide
NS-5 NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32. BOC Sciences 5
NS5806 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 5806 NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS 5806 NS5806 is a KV4.3 channel activator. It can mediate the transient outward K+ current (Ito). Synonyms: NS-5806; NS 5806; NS5806; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 426834-69-7. Molecular formula: C16H8Br2F6N6O. Mole weight: 574.07. BOC Sciences 10
NS6180 NS6180 is a potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). NS6180 prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease. Synonyms: NS6180; NS-6180; NS 6180. Grades: 98%. CAS No. 353262-04-1. Molecular formula: C16H12F3NOS. Mole weight: 323.33. BOC Sciences 10
NS6180 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
NS 6180 NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NS-638 NS-638 is a small nonpeptide Ca(2+)-channel blocker. Synonyms: 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine; 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole; NS 638; NS-638. CAS No. 150493-34-8. Molecular formula: C15H11ClF3N3. Mole weight: 325.72. BOC Sciences 10
NS 6740 NS 6740 is an α7 nAChR partial agonist displaying anti-inflammatory activity. It reduces LPS-induced TNF-α release from microglia enriched cultures. Synonyms: 1,4-Diazabicyclo[3.2.2]non-4-yl[5-[3-(trifluoromethyl)phenyl]-2-furanyl]methanone hydrochloride. Grades: ≥98% by HPLC. CAS No. 753499-14-8. Molecular formula: C19H19F3N2O2·HCl. Mole weight: 400.82. BOC Sciences 10
NS8593 An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels in a Ca2+-dependent manner. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
NS 8593 hydrochloride NS8593 HCl is a selective KCa2 channel negative modulator. Synonyms: NS 8593 hydrochloride; NS8593 hydrochloride; NS-8593 hydrochloride; N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 875755-24-1. Molecular formula: C17H17N3.HCl. Mole weight: 299.8. BOC Sciences 10
NS8593 hydrochloride NS8593 hydrochloride is a potent and selective small conductance Ca 2+ -activated K + channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3 -mediated currents with a K d value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca 2+ -dependently ( K d s of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca 2+ ), and does not affect the Ca 2+ -activated K + channels of intermediate and large conductance (hIK and hBK channels, respectively) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-110105. MedChemExpress MCE
NS8593 hydrochloride ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
NS8593 ((R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine) An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
NS 9283 NS 9283 is an allosteric modulator of α4β2 receptor affecting the potency of acetylcholine related events. It can reduce the rate of recovery from desensitization and slow the rate of deactivation. Synonyms: NS9283; NS 9283; NS-9283; 3-[3-(3-Pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile. Grades: ≥99% by HPLC. CAS No. 913830-15-6. Molecular formula: C14H8N4O. Mole weight: 248.24. BOC Sciences 10
NS 9283 NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
NSAH NSAH is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC 50 of 32 μM and cell-based IC 50 of ~250 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1099592-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114503. MedChemExpress MCE
N-Salicylideneaniline N-Salicylideneaniline. Group: Biochemicals. Alternative Names: N-Salicylalaniline. Grades: Highly Purified. CAS No. 779-84-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. USBiological 8
Worldwide
N-Salicylidene p-bromoaniline N-Salicylidene p-bromoaniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SALICYLIDENE-(P-BROMOANIL);SALICYLIDENE P-BROMOANILINE;TIMTEC-BB SBB007908;O-[N-(P-BROMOPHENYL)FORMIMIDOYL]PHENOL;N-SALICYLIDENE P-BROMOANILINE;2-(((4-bromophenyl)imino)methyl)-pheno;2-(((4-bromophenyl)imino)methyl)phenol;2-((E)-[(4-Bromophenyl)imino]met. Product Category: Heterocyclic Organic Compound. CAS No. 886-34-0. Molecular formula: C13H10BrNO. Mole weight: 276.13. Purity: 0.96. IUPACName: 6-[(4-bromoanilino)methylidene]cyclohexa-2,4-dien-1-one. Canonical SMILES: C1=CC(=CNC2=CC=C(C=C2)Br)C(=O)C=C1. Density: 1.385g/cm³. Product ID: ACM886340. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3

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