A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
NSC 693868. Group: Biochemicals. Grades: Purified. CAS No. 40254-90-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NSC697923
Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (Diffuse large B cell lymphoma) cells. Group: Biochemicals. Alternative Names: 2-[(4-Methylphenyl)sulfonyl]-5-nitro-Furan, 2-Nitro-5-tosylfuran. Grades: Highly Purified. CAS No. 343351-67-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H?NO?S. US Biological Life Sciences.
Worldwide
NSC697923
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity. Synonyms: NSC 697923; NSC-697923; Furan, 2-[(4-methylphenyl)sulfonyl]-5-nitro-; 2-Nitro-5-(toluene-4-sulfonyl)-furan. Grades: >98%. CAS No. 343351-67-7. Molecular formula: C11H9NO5S. Mole weight: 267.26.
NSC 697923
NSC 697923. Group: Biochemicals. Grades: Purified. CAS No. 343351-67-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NSC 74859
NSC 74859. Group: Biochemicals. Grades: Purified. CAS No. 501919-59-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NSC 756093
NSC 756093 is the first inhibitor of GBP1 and PIM1 interaction with activity in paclitaxel resistant cells. Synonyms: AOB6494; AOB 6494; AOB-6494; NSC756093; NSC-756093; NSC 756093; 4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenylfuro[3,4-b]quinolin-1(3H)-one. Grades: 99%. CAS No. 1629908-92-4. Molecular formula: C20H19NO4. Mole weight: 337.37.
NSC781406
NSC781406 demonstrates potent PI3K inhibition (PI3Kα IC50=2.0 nM) and is a highly potent mTOR inhibitor, with reasonable liver microsome stability. Synonyms: NSC-781406; NSC 781406; NSC781406; 2,4-difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide; CHEMBL3763244; BDBM50145412. CAS No. 1676893-24-5. Molecular formula: C29H27F2N5O5S2. Mole weight: 627.68.
NSC87877
NSC87877 is a cell-permeable, inhibitor of both SHP-1 and SHP-2 with IC50 values of 355nm and 318 nM, respectively. It shows effective growth inhibition and induction of apoptosis in NB cell lines. It is much less effective against other protein tyrosine phosphatases and the dual-specificity phosphatase 26. It blocks epidermal growth factor receptor-induced activation of Ras and ERK1/2 in HEK293 cells, stimulates store-operated calcium entry in response to thrombin in platelets, and increased acetylcholine receptor clustering in myotubes. Synonyms: NSC-87877; 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-; (E)-8-hydroxy-7-((6-sulfonaphthalen-2-yl)diazenyl)quinoline-5-sulfonic acid. Grades: >98 %. CAS No. 56990-57-9. Molecular formula: C19H13N3O7S2. Mole weight: 459.45.
NSC 87877
NSC 87877. Group: Biochemicals. Alternative Names: 8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonic Acid. Grades: Highly Purified. CAS No. 56990-57-9. Pack Sizes: 100mg. Molecular Formula: C20H14N2O7S2, Molecular Weight: 458.46. US Biological Life Sciences.
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NSC 87877 sodium
NSC 87877 is a potent cell-permeable inhibitor of SHP-1/2 PTPs. It dose-dependently inhibits dual-specificity protein phosphatase 26 (DUSP26) which is involved in survival of anaplastic thyroid cancer (ATC) cells, suggesting that it has the potential for treating thyroid cancer. Synonyms: Disodium 8-hydroxy-7-[(6-sulphonato-2-naphthyl)azo]quinoline-5-sulphonate. CAS No. 56932-43-5. Molecular formula: C19H13N3O7S2·2Na. Mole weight: 503.42.
NSC 95397. Group: Biochemicals. Grades: Purified. CAS No. 93718-83-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NSC 95397
NSC 95397 is a 1,4-naphthoquinone-based irreversible inhibitor of Cdc25 dual-specificity phosphatases (Ki = 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). NSC 95397 exhibits 125-180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Synonyms: 2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone; NSC-95397; NSC95397; NSC 95397. Grades: ≥97% by HPLC. CAS No. 93718-83-3. Molecular formula: C14H14O4S2. Mole weight: 310.38.
N,S-Carboxymethyl Cysteine HCl
N,S-Carboxymethyl Cysteine HCl is one of Cysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: N,S-bis(carboxymethyl)cysteine, hydrochloride (1:1). Grades: > 95%. Molecular formula: C7H11NO6S.HCl. Mole weight: 273.69.
Ns-D1
Ns-D1 is an antimicrobial peptide found in seeds, Nigella sativa L. (Ranunculaceae). It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. It is a plant defensin containing four disulfide bridges. Synonyms: Defensin D1. Grades: >85%. Molecular formula: C232H347N69O70S8. Mole weight: 5479.26.
Ns-D2
Ns-D2 is an antimicrobial peptide found in seeds, Nigella sativa L. (Ranunculaceae). It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. It is a plant defensin containing four disulfide bridges. Synonyms: Defensin D2. Grades: >85%. Molecular formula: C233H351N69O70S8. Mole weight: 5495.31.
NSD2-PWWP1-IN-2
NSD2-PWWP1-IN-2 (compound 33) is a potent NSD2-PWWP1 inhibitor with an IC 50 value of 1.49 μM. NSD2-PWWP1-IN-2 has the potential for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2797183-32-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171120.
N,S-Diacetyl-L-cysteine
A double-prodrugs of L-cysteine. Group: Biochemicals. Alternative Names: N-Acetylcysteine. Grades: Highly Purified. CAS No. 18725-37-6. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
N,S-Dicarboxymethyl-L-cysteine
N,S-Dicarboxymethyl-L-cysteine is an impurity of carbocysteine. Synonyms: N,S-Bis(carboxymethyl)-L-cysteine; Niraparib Impurity compound (c); (2R)-2-(carboxymethylamino)-3-(carboxymethylsulfanyl)propanoic acid; L-Cysteine, N,S-bis(carboxymethyl)-. Molecular formula: C7H11NO6S. Mole weight: 237.23.
N-(S)-Glycidylphthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid. Group: Biochemicals. Alternative Names: (S)-2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione; (S) -2-[ (Oxiranyl) methyl]isoindole-1, 3-dione; (S)-N-(2,3-Epoxypropan-1-yl)phthalimide; (S) -N- (2, 3-Epoxypropyl) phthalimide; 2-[(S)-2-Oxiranylmethyl]-1H-isoindol-1,3(2H)-dione; N-((2S)-Oxiran-2-ylmethyl)phthalimide. Grades: Highly Purified. CAS No. 161596-47-0. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
NSI-189
NSI-189 is an orally active chemical entity with enhanced neurogenic activity. NSI-189 up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. NSI-189 exhibits anti-depressant effect. NSI-189 enhances synaptic plasticity and reduces cognitive dysfunction. NSI-189 holds potential for psychiatric disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1270138-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13999.
NSI-189
NSI-189 is an experimental drug being studied by Neuralstem, Inc. Research into NSI-189 has been funded by the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH) for the treatment of major depressive disorder. NSI-189 successfully completed a phase 1 clinical trial in 2011 where it was administered to 41 healthy volunteers. A phase 1b clinical trial for treating major depressive disorder in 24 patients started in 2012 and completed in July 2014. The study suggests that there were improvements in the patients' condition when the doses were 40/80 mg per day, but no significant improvements were seen for a higher dosage of 120 mg/day. Neuralstem intends to pursue further clinical trials for a variety of neurological conditions, including major depressive disorder, traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging. Uses: For research used only. Synonyms: NSI-189; NSI 189; NSI189. Grades: 98%. CAS No. 1270138-40-3. Molecular formula: C22H30N4O. Mole weight: 366.5.
NSI-189 phosphate
NSI-189 is an orally active chemical entity with enhanced neurogenic activity. NSI-189 up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. NSI-189 exhibits anti-depressant effect. NSI-189 enhances synaptic plasticity and reduces cognitive dysfunction. NSI-189 holds potential for psychiatric disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1270138-41-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13999A1.
N-SMP
A useful protective group in antibody drug conjugates. Synonyms: 1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione; N-(α-Maleimidoacetoxy)succimide; AMAS; N-Succinimidyl maleimidoacetate; n-succinimidyl maleimidoacetate; N-(|A-Maleimidoacetoxy)succinimide; Maleimidoacetic Acid N-Succinimidyl Ester; N-(alpha-Maleimidoacetoxy)succinimide; a-Maleimidoacetic acid-NHS. Grades: ≥ 98%. CAS No. 55750-61-3. Molecular formula: C10H8N2O6. Mole weight: 252.18.
N-(S-Nitroso-N-acetyl-D,L-penicillamine)-2-amino-2-deoxy-1,3,4,6-tetra-O-acetyl-b-D-glucopyranose, commonly referred to as NAPD, represents a remarkable and influential compound extensively employed in the field of biomedicine for investigating and addressing a myriad of diseases. Prominently, this extraordinary product has proven immensely advantageous in scientific exploration concerning cancer, inflammation, and cardiovascular disorders, demonstrating its vital role in the advancement of innovative and cutting-edge therapeutic interventions. Synonyms: 2-[[(2S)-2-(Acetylamino)-3-methyl-3-(nitrosothio)-1-oxobutyl]amino]-2-deoxy-b-D-glucopyranose 1,3,4,6-tetraacetate; RIG200. CAS No. 202656-49-3. Molecular formula: C21H31N3O12S. Mole weight: 549.55.
NSP-805
NSP-805 is a potent and selective inhibitor of guinea pig cardiac phosphodiesterase 3 (PDE3) , and a cardiotonic agent with vasodilator properties. Uses: Scientific research. Group: Signaling pathways. CAS No. 125068-54-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-19102.
NSP-DMAE-HEG-Glu-NHS
It belongs to the group of acridine chemiluminescent markers. Synonyms: Acridinium, 9-[[4-[[[1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,5-dioxo-9,12,15,18,21-pentaoxa-6-azatricos-23-yl]amino]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)-, inner salt. Grades: ≥90%. CAS No. 1253933-74-2. Molecular formula: C47H58N4O16S. Mole weight: 967.05.
NSP-DMAE-NHS
NSP-DMAE-NHS is an acridinium ester chemiluminescent reagent containing N-sulfopropyl groups. It is useful in the clinical diagnostic industry especially in automated immunochemical analyzers such as Siemens Healthcare Diagnostics' ADVIA Centaur systems. Synonyms: 2',6'-Dimethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS Ester; 2',6'-Dimethyl-4'-(N-succinimidyloxycarbonyl) phenyl-10-sulfopropylacridinium-9-carboxylate; 9-[[4-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)acridinium Inner Salt. Grades: ≥98% by HPLC. CAS No. 194357-64-7. Molecular formula: C30H26N2O9S. Mole weight: 590.60.
It is a direct chemiluminescent reagent, used to mark proteins, antigens, antibodies, nucleic acids (DNA, RNA), etc. Synonyms: 3-[9- ( ( (3- (N-succinimidyloxycarboxypropyl) [4-methxylphenyl]sulfonyl) amine) carboxyl]-10-acridiniumyl) -1-propanesulfonate; 3-(9-((4-((2,5-Dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)(tosyl)carbamoyl)acridin-10-ium-10-yl)propane-1-sulfonate; 9-[[[4-[ (2, 5-Dioxo-1-pyrrolidinyl) oxy]-4-oxobutyl][ (4-methylphenyl) sulfonyl]amino]carbonyl]-10- (3-sulfopropyl) -acridinium inner salt. Grades: ≥95%. CAS No. 199293-83-9. Molecular formula: C32H31N3O10S2. Mole weight: 681.73.
N-Stearoylglycine
N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Stearoylglycine; N-Octadecanoylglycine. CAS No. 6333-54-6. Pack Sizes: 250 mg. Product ID: HY-W141932.
N-Stearoyl-L-cysteine
N-Stearoyl-L-cysteine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
N-Stearoyl phytosphingosine. Group: Biochemicals. Alternative Names: N- [ (1S, 2S, 3R) -2, 3-Dihydroxy-1- (hydroxymethyl) heptadecyl] octadecanamide; C18 3-hydroxy dihydroceramide; Ceramide III. Grades: Highly Purified. CAS No. 34354-88-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C36H73NO4. US Biological Life Sciences.
Worldwide
N-Stearoyl Taurine
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered.2 This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3 N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Uses: Scientific research. Group: Signaling pathways. CAS No. 63155-80-6. Pack Sizes: 1 mg (2.55 mM * 1 mL in Methanol). Product ID: HY-120964.
N-Stearoyltyrosine methyl ester
Heterocyclic Organic Compound. CAS No. 122445-70-9. Catalog: ACM122445709.
N-SuberyLglycine (2,2-D2)
Isotope-labeled Amino Acids2H Labeled Compounds. Alternative Names: N-Suberylglycine-2,2-D2. CAS No. 1219799-02-6. Molecular formula: C10H15D2NO5. Mole weight: 233.26. Appearance: White powder. Catalog: ACM1219799026.
N-substituted formamide deformylase
Zinc is a cofactor. While N-benzylformamide is the best substrate, the enzyme from Arthrobacter pascens can also act on the N-substituted formamides N-butylformamide, N-allylformamide, N-[2-(cyclohex-1-enyl)ethyl]formamide and N-(1-phenylethyl)formamide, but much more slowly. Amides of other acids do not act as substrates. Group: Enzymes. Synonyms: NfdA. Enzyme Commission Number: EC 3.5.1.91. CAS No. 115299-95-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4483; N-substituted formamide deformylase; EC 3.5.1.91; 115299-95-1; NfdA. Cat No: EXWM-4483.
Heterocyclic Organic Compound. Alternative Names: N-[[N-[ (Succinimidooxy)carbonyl]-β -alanyl]oxy]succinimide. CAS No. 1215667-16-5. Molecular formula: C16H21N3O10. Mole weight: 415.35. Appearance: White Solid. Catalog: ACM1215667165.
N-Succinimidyl 11-(maleimido)undecanoate
Maleimide-C10-NHS ester is a PROTAC linker, which is composed of alkyl chains. Maleimide-C10-NHS ester can be used to synthesize a range of PROTACs. Synonyms: KMUS; Maleimide-C10-NHS ester; N-Succinimidyl 11-maleimidoundecanoate; 11-Maleimidoundecanoic Acid N-Succinimidyl Ester; 2,5-dioxopyrrolidin-1-yl 11-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoate; Maleimide-(CH2)10-COONHS; 11-Maleimidoundecanoicacid-NHS; 11-(Maleimido)undecanoic acid N-succinimidyl ester; VZ21668; 11-Maleimidoundecanoic acid-NHS (KMUS); 2,5-Dioxo-3-pyrroline-1-undecanoic acid succinimidyl ester. Grades: 95%. CAS No. 87981-04-2. Molecular formula: C19H26N2O6. Mole weight: 378.42.
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 6.2 Angstroms. Group: Biochemicals. Alternative Names: SBAP. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A compound used potentially for the radioiodination of monoclonal antibodies. Used in Antibody labelling. Group: Biochemicals. Alternative Names: 1-[[3- (Trimethylstannyl) benzoyl]oxy]-2, 5-pyrrolidinedione; 3- (Trimethylstannyl) benzoic Acid 2,5-dioxo-1-pyrrolidinyl Ester. Grades: Highly Purified. CAS No. 122856-01-3. Pack Sizes: 5mg. US Biological Life Sciences.
A fluorinated aryl azide which can be used for the photofunctionalization of polymer surfaces.l max = 273nm; e= 23 x 10-3. Group: Biochemicals. Alternative Names: 4-Azido-2,3,5,6-tetrafluorobenzoic Acid, N-Succinimidyl Ester, ATFB SE. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-Succinimidyl 4-Azidosalicylate
A aryl azide which can be used for the photofunctionalization of polymer surfaces. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-Succinimidyl (4-iodoacetyl) aminobenzoate
N-Succinimidyl (4-iodoacetyl) aminobenzoate. Group: Biochemicals. Alternative Names: 4-[ (2-Iodoacetyl) amino]benzoic acid 2,5-dioxo-1-pyrrolidinyl ester; SIAB. Grades: Highly Purified. CAS No. 72252-96-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C13H11IN2O5. US Biological Life Sciences.