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| Product | Description | |
|---|---|---|
| N-Salicyloyltryptamine | N-Salicyloyltryptamine acts on voltage-dependent Na + , Ca 2+ , and K + ion channels inhibitor. N-Salicyloyltryptamine inhibits K + currents with an IC 50 value of 34.6 μM ( I to ). N-Salicyloyltryptamine also exhibits anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect [1] - [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31384-98-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147377. |  |
| N-Salicyloyltryptamine | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| NSC 107512 | NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22242-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-141687. | |
| NSC109555 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 109555 | NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences. |  Worldwide |
| NSC 109555 dimesylate | NSC 109555 is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), displaying no effect against other kinases. It inhibits H1 phosphorylation and attenuates mitochondrial ATP synthesis. NSC 109555 can be used in cancer therapy. Synonyms: DDUG; NCI C04808; Carbanilide, 4,4'-diacetyl-, 4,4'-bis(amidinohydrazone), dimethanesulfonate. CAS No. 15427-93-7. Molecular formula: C19H24N10O·2CH3SO3H. Mole weight: 600.7. |  |
| NSC 109555 ditosylate | NSC-109555 Ditosylate is an ATP-competitive Chk2 inhibitor with IC50 value of 0.2 μM. It acts by inhibiting histone H1 phosphorylation and attenuating mitochondrial ATP synthesis. It is an antileukemic agent. Synonyms: NSC-109555 Ditosylate; NSC 109555 Ditosylate; NSC109555 Ditosylate; 4,4'-diacetyldiphenylurea bis(guanylhydrazone) ditosylate. Grades: ≥98% by HPLC. CAS No. 66748-43-4. Molecular formula: C19H24N10O.2C7H8O3S. Mole weight: 752.86. | |
| NSC 109555 ditosylate | NSC 109555 ditosylate. Group: Biochemicals. Grades: Purified. CAS No. 66748-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC12 | NSC12 is an extracellular trap for fibroblast growth factor 2 (FGF2). It binds FGF2 with Kd value of 51 μM and interferes with its interaction with FGFR1 without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans. It also binds several other FGF isoforms and prevents them from forming HSPG/FGF/FGFR ternary complexes. It inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduces tumor growth in mice. It inhibited the proliferation of different FGF-dependent tumour cell lines, but had no inhibitory effect on FGF-independent tumour cells expressing a constitutively active FGFR1. It was shown to inhibit FGFR phosphorylation, angiogenesis and primary and metastatic tumour growth of FGF-dependent human and mouse cancer cells in vivo. It has significant implications in cancer therapy. Uses: Nsc12 has significant implications in cancer therapy. Synonyms: NSC-12; NSC 12; NSC12; NSC 172285; NSC-172285; NSC172285; 21- (Hydroxy (bistrifluoromethyl)methyl)pregnane-3, 20-diol; Pregn-5-ene-3, 20-diol, 21-(2-hydroxy-1,1,1,3,3,3-hexafluoro-2-propyl)-;LS-118618;4,4,4-Trifluoro-1-[(8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-3-(trifluoromethyl)butane-1,3-diol;NSC-12;NSC-172285;NSC172285;(R)-4,4,4-trifluoro-1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-3-(trifluoromethyl)butane-1,3-diol. Grades: >98 %. CAS No. 102586-30-1. Molecular formula: C24H34F6O3. Mole weight: 484.52. | |
| NSC125066 | NSC125066 Inhibitor. Uses: Scientific use. Product Category: T6116. CAS No. 9041-93-4. |  |
| NSC130813 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC134754 | NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. NSC134754 can also completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells. Uses: Amti-tumor. Synonyms: NZ-28; NZ28; NZ 28; NSC 134754; NSC 134754; NSC134754. (S)-3-ethyl-9,10-dimethoxy-2-(((R)-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline. Grades: 98%. CAS No. 75041-32-6. Molecular formula: C27H34N2O2. Mole weight: 418.58. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride is a genotype-selective antitumor agent. It can activate p53-dependent transcription. Synonyms: NSC 146109 hydrochloride; NSC146109 hydrochloride; NSC-146109 hydrochloride; (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride. Grades: ≥99% by HPLC. CAS No. 59474-01-0. Molecular formula: C17H16N2S.HCl. Mole weight: 316.85. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 59474-01-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 15364 | NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4550-72-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108937. | |
| NSC156529 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC16168 | NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 ?M. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6837-93-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100690. | |
| NSC 162535 disodium salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 177223 | NSC 177223. Group: Biochemicals. Alternative Names: 4-Amino-5,8-dihydro-5-oxo-8- β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; API-1. Grades: Highly Purified. CAS No. 36707-00-3. Pack Sizes: 5mg. Molecular Formula: C13H15N5O6, Molecular Weight: 337.29. US Biological Life Sciences. | Worldwide |
| NSC 185058 | NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39122-38-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125169. | |
| NSC 185058 | NSC 185058 is an inhibitor of ATG4B that inhibits ATG4B activity in vitro and in cells with no effect against MTOR and PtdIns3K. It inhibited autophagy and exhibited a negative impact on the development of Saos-2 osteosarcoma tumors in vivo. Synonyms: N-(pyridin-2-yl)pyridine-2-carbothioamide. Grades: ≥98%. CAS No. 39122-38-8. Molecular formula: C11H9N3S. Mole weight: 215.3. | |
| NSC 194308 | NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90379-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153736. | |
| NSC 207895 | NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. Synonyms: NSC 207895; NSC-207895; NSC207895; XI-006; XI006; XI 006. Grades: >98%. CAS No. 58131-57-0. Molecular formula: C11H13N5O4. Mole weight: 279.25. | |
| NSC 210902 | NSC 210902 is an ATP-competitive inhibitor of casein kinase 2 (CK2). It inhibits CK2 which is increased in tumor tissues, suppressing the proliferation of cancer cells. Synonyms: 4-oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid. Grades: ≥95%. CAS No. 51726-83-1. Molecular formula: C14H9NO3. Mole weight: 239.2. | |
| NSC 228155 | NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR[1]. NSC 228155 is also a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 ?M[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 113104-25-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101084. | |
| NSC 228155 | NSC 228155 is an EGFR activator that binds to the dimerization domain II of sEGFR. It inhibits KIX-KID interaction with IC50 value of 0.36 μM. Synonyms: NSC228155; NSC-228155; 7-nitro-4-(1-oxidopyridin-1-ium-2-yl)sulfanyl-2,1,3-benzoxadiazole. CAS No. 113104-25-9. Molecular formula: C11H6N4O4S. Mole weight: 290.25. | |
| NSC 23005 sodium | NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Synonyms: NSC 23005 sodium; NSC23005 sodium; NSC-23005 sodium; 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1796596-46-7. Molecular formula: C13H16NNaO4S. Mole weight: 305.33. | |
| NSC 23005 Sodium Salt | NSC 23005 Sodium Salt is used to perpare sodium sodium cyclohexyl aminosulfonyl benzoate as p18 micromolecule inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1796596-46-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H16NNaO4S, Molecular Weight: 305.33. US Biological Life Sciences. | Worldwide |
| NSC 23005 Sodium Salt | Cas No. 6314-70-1. | |
| NSC232003 | NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. Uses: Scientific research. Group: Signaling pathways. CAS No. 1905453-18-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-103236. | |
| NSC232003 | NSC232003, a uracil derivative freely available by the NCI/DTP Repository, is an effective DNA methylation inhibitor. Synonyms: NSC232003; NSC 232003; NSC-232003; (5Z)-5-[1-(hydroxyamino)ethylidene]pyrimidine-2,4-dione. CAS No. 1905453-18-0. Molecular formula: C6H7N3O3. Mole weight: 169.14. | |
| NSC 23766 | NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase. It does not inhibit the closely related targets, Cdc42 or RhoA. Synonyms: NSC 23766; NSC23766; NSC-23766. Grades: >98%. CAS No. 733767-34-5. Molecular formula: C24H35N7. Mole weight: 421.58. | |
| NSC 23766 | NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment. Uses: Scientific research. Group: Signaling pathways. CAS No. 733767-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15723. | |
| NSC 23766 trihydrochloride | NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Synonyms: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. Grades: ≥98%. CAS No. 1177865-17-6. Molecular formula: C24H38Cl3N7. Mole weight: 530.967. | |
| NSC 23766 trihydrochloride | NSC 23766 trihydrochloride is an inhibitor of Rac1 activation. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177865-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15723A. | |
| NSC23766 trihydrochloride | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC23925 | NSC23925 is a novel, selective and effective P-glycoprotein ( Pgp ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 858474-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19626. | |
| NSC23925 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 23925 | NSC 23925 is a potent plasma membrane glycoprotein 1 (Pgp1) inhibitor that reverses multidrug resistance (MDR1) mediated by Pgp1 without inhibitory effect against MRP or BCRP-mediated MDR1. NSC 23925 can prevent MDR1 in ovarian cancer both in vitro and in vivo. Synonyms: (2-(4-methoxyphenyl)quinolin-4-yl)(piperidin-2-yl)methanol dihydrochloride. Grades: ≥98%. CAS No. 858474-14-3. Molecular formula: C22H24N2O2·2HCl. Mole weight: 421.4. | |
| NSC 245214 | NSC 245214 is a thienyl cycloalkanone that is part of the US National Cancer Institute small molecule repository. The biological activity of this compound has not been reported. Group: Biochemicals. Alternative Names: 2-(3,5-dinitro-2-thienyl)-cyclohexanone. Grades: Highly Purified. CAS No. 31554-45-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C10H10N2O5S, Form: Supplied as a crystalline. US Biological Life Sciences. | Worldwide |
| NSC-26326 | NSC-26326 Inhibitor. Uses: Scientific use. Product Category: T6407. CAS No. 4707-32-8. | |
| NSC 280449 | NSC 280449 is a derivative of Tromethamine (T892600); a compound that is widely used in biochemistry and molecular biology. In medicine, Tromethamine is used as an alternative to sodium bicarbonate in the treatment of metabolic acidosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60204-53-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H17NO3, Molecular Weight: 199.25. US Biological Life Sciences. | Worldwide |
| NSC2805 | NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 ?M. NSC2805 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4371-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134417. | |
| NSC 295642 | NSC 295642. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC 295642, [1-(2-pyridinyl)ethylidene]-Hydrazinecarbodithioic acid, phenylmethyl ester, copper complex, 77111-29-6, Bis-[chloro[phenylmethyl [1-(2-pyridinyl)ethylidene]hydrazinecarbodithioato-N2,N2 inverted exclamation marka,S1 inverted exclamation mark ]-copper], Cu(II) complex of the Schiff base product of condensation of S-benzyl dithiocarbazate and 2-acetylpyridine. Product Category: Heterocyclic Organic Compound. CAS No. 77111-29-6. Molecular formula: C15H14ClCuN3S2. Mole weight: 798.84. Purity: 0.96. IUPACName: (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+). Canonical SMILES: CC(=NN=C([S-])SCC1=CC=CC=C1)C2=CC=CC=N2.Cl[Cu+]. Product ID: ACM77111296. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID20444568. |  |
| NSC305787 | NSC305787 is a small molecule inhibitor of PKC. Its IC50 value is 8.3 μM, 9.4 μM, 55 μM for PKC&Lota; phosphorylation of recombinant ezrin, moesin and radixin. It is proved a novel targeted therapy which could inhibit ezrin protein as an approach to prevent tumor metastasis in vitro. It could inhibited T567 phosphorylation and actin binding of endogenous ezrin at 10 μM without altering cellular ezrin levels and inhibit the lung metastases growth of high-ezrin-expressing K7M2 OS cells in this organ culture assay. It cause reduced cell motility phenotypes in zebrafish in vivo. Uses: Nsc305787 is proved a novel targeted therapy which could inhibit ezrin protein as an approach to prevent tumor metastasis in vitro. it could inhibited t567 phosphorylation and actin binding of endogenous ezrin at 10 μm without altering cellular ezrin levels and inhibit the lung metastases growth of high-ezrin-expressing k7m2 os cells in this organ culture assay. Synonyms: NSC 305787; NSC-305787; NSC 305787. Grades: >98%. CAS No. 785718-37-8. Molecular formula: C25H30Cl2N2O. Mole weight: 445.42. | |
| NSC305787 hydrochloride | NSC305787 hydrochloride is a small molecule inhibitor of PKC (IC50=8.3 μM) that directly inhibits ezrin protein as an approach to prevent tumor metastasis. Uses: A small molecule inhibitor of pkc. Synonyms: NSC-305787 Hydrochloride; NSC 305787 Hydrochloride; NSC305787 Hydrochloride; NSC-305787 HCl; NSC 305787 HCl; NSC305787 HCl; [2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride;[2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride. Grades: ≥95%. CAS No. 53868-26-1. Molecular formula: C25H31Cl3N2O. Mole weight: 481.89. | |
| NSC308848 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| NSC319726 | NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZMC1. CAS No. 71555-25-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18634. | |
| NSC 319726 | NSC 319726. Group: Biochemicals. Grades: Purified. CAS No. 71555-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 319726 | NSC319726 is a p53(R175) mutant reactivator, exhibits growth inhibition in cells expressing mutant p53, with IC50 of 8 nM for p53(R175) mutant, shows no inhibition for p53 wild-type cells. Synonyms: NSC-26386; NSC-319726; NSC 26386; NSC 319726; NSC26386; NSC319726. Grades: >98%. CAS No. 71555-25-4. Molecular formula: C11H14N4S. Mole weight: 234.32. | |
| NSC 33994 | NSC 33994. Group: Biochemicals. Grades: Purified. CAS No. 82058-16-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 33994 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 33994 | NSC-33994 is a selective inhibitor of JAK2 with IC50 of 60 nM. Synonyms: NSC-33994; NSC 33994; NSC33994; E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol. Grades: ≥98% by HPLC. CAS No. 82058-16-0. Molecular formula: C28H42N2O2. Mole weight: 438.65. | |
| NSC-33994 | NSC-33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies. Group: Biochemicals. Alternative Names: 4, 4'-[ (1E) -1, 2-Diethyl-1, 2-ethenediyl]bis[2-[ (diethylamino) methyl]phenol; (E) -4, 4'- (1, 2-Diethyl-1, 2-ethenediyl) bis[2-[ (diethylamino) methyl]phenol. Grades: Highly Purified. CAS No. 82058-16-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| NSC348884 | NSC 348884 is a putative inhibitor of nucleophosmin (NPM). It is a small molecule that inhibits the formation of nucleophosmin dimers by disrupting a defined hydrophobic pocket required for oligomerization. It can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 μM. It disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Uses: Nsc 348884 inhibits the formation of nucleophosmin dimers. it can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell line. it disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Synonyms: NSC348884; NSC 348884; NSC-348884; N1,N1,N2,N2-Tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]-1,2-ethanediamine;1,2-EthanediaMine, N,N,N',N'-tetrakis[(5-Methyl-1H-benziMidazol-2-yl)Methyl]- ;N,N,N',N'-tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine. Grades: >98%. CAS No. 81624-55-7. Molecular formula: C38H40N10. Mole weight: 636.79. | |
| NSC 37249 dihydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 3852 | NSC 3852. Group: Biochemicals. Grades: Purified. CAS No. 3565-26-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 3852 | NSC 3852 is a histone deacetylase inhibitor. It is shown to have cell differentiation and antiproliferative activity in human breast cancer cells. Synonyms: NSC 3852; NSC3852; NSC-3852; 5-Nitroso-8-quinolinol. Grades: ≥95% by HPLC. CAS No. 3565-26-2. Molecular formula: C9H6N2O2. Mole weight: 174.16. | |
| NSC405020 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC 405020 | NSC-405020 is a novel small molecule inhibitor of MT1-MMP that specifically targets PEX domain rather than the catalytic domain of MT1-MMP with IC50 >100 μM and does not inhibit the catalytic activity of MT1-MMP or MMP-2. Synonyms: TWS119; TWS 119; TWS-119. CAS No. 7497-7-6. Molecular formula: C12H15Cl2NO. Mole weight: 260.158. | |
| NSC 405020 | NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7497-7-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15827. | |
| NSC 405020 | NSC 405020. Group: Biochemicals. Grades: Purified. CAS No. 7497-7-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC-41589 | N-[2-(methylsulfanyl) phenyl]acetamide. Synonyms: NSC-41589; NSC 41589; NSC41589. Grades: >98%. CAS No. 6310-41-4. Molecular formula: C9H11NOS. Mole weight: 181.25. | |
| Nsc42165 | Nsc42165. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nsc42165. Product Category: Heterocyclic Organic Compound. CAS No. 17596-06-4. Mole weight: 0. Product ID: ACM17596064. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,4'-(Diazoamino)dibenzenesulfonic acid. | |
| NSC 42834 | NSC 42834 (JAK2 Inhibitor V), a novel specific inhibitor of Jak2, inhibits Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAK2 Inhibitor V; Z3. CAS No. 195371-52-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15480. | |
| NSC 42834 | A cell-permeable pyridinylbutanone compound that inhibits cellular autophosphorylation of both the wild-type Jak2 and the constitutively active V167F mutant (IC50 = 15 & 28 μM, respectively, with WT- & V617F-transfected BSC-40 cells), while exhiting no effect against cellular Tyk2 autophosphorylation in COS cells or c-Src kinase in cell-free kinase assays. Z3 suppresses the Jak2-V167F-dependent proliferation of the erythroleukemia cell line HEL by blocking the G1-S transition and is shown to effectively reduce the cytokine-stimulated growth of both Jak2-V617F-positive and Jak2-F537I-positive primary hematopoietic progenitor cells from myeloproliferative disorder patients. Synonyms: NSC 42834; NSC-42834; NSC42834; Z3; 1-Butanone, 2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-. Grades: >98%. CAS No. 195371-52-9. Molecular formula: C23H24N2O. Mole weight: 344.45. | |
| NSC43067 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC57969 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NSC5844 | NSC5844 is a CCR1 agonist and a bisquinoline compound. Synonyms: N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine; NSC5844; NSC-5844; NSC 5844; RE640; RE-640; R E640. CAS No. 140926-75-6. Molecular formula: C20H16Cl2N4. Mole weight: 383.27. | |
| NSC59984 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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