A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
N-tris (Hydroxymethyl)methyl-3-aminopropanesulfonic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
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N-tris (Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium salt
N-tris (Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium salt. Group: Biochemicals. Alternative Names: TAPS sodium salt; [2-Hydroxy-1, 1-bis (hydroxymethyl) ethyl]amino-1-propanesulfonic acid sodium salt. Grades: Highly Purified. CAS No. 91000-53-2. Pack Sizes: 250g. US Biological Life Sciences.
Worldwide
N-tris (Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium salt 98+%
N-tris (Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium salt 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 91000-53-2. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
N-tris (Hydroxymethyl) methylglycine 99+%
N-tris (Hydroxymethyl) methylglycine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
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N-Trithyl Losartan
N-Trithyl Losartan is an intermediate in the preparation of Losartan impurities. Synonyms: 2-Butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-2-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole. Grades: > 95%. CAS No. 124751-00-4. Molecular formula: C41H37ClN6O. Mole weight: 665.24.
N-Tritriacontane
N-Tritriacontane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TRITERPENOIDS KIT; TRITRIACONTANE; ALKANE C33; TRITRIACONTANE,STANDARD FOR GC; tritiacontane; N-TRITIACONTANE; N-TRITRIACONTANE; Tritriacontan; n-Triatriacontane. Product Category: Heterocyclic Organic Compound. Appearance: white flakes. CAS No. 630-05-7. Molecular formula: C33H68. Mole weight: 464.9. Purity: 0.96. IUPACName: tritriacontane. Density: 0.81g/cm³. Product ID: ACM630057. Alfa Chemistry ISO 9001:2015 Certified.
Protected, labeled cyclic propano guanine adduct DNA acetaldehyde histone. Group: Biochemicals. Alternative Names: N-Trityl-5,6,7,8-tetrahydro-4-hydroxy-6-methylpyrimido[1,2-a]purin-10(1H)-one-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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N-Trityl-5-(2-fluorophenyl)-1H-tetrazole
A protected intermediate in the preparation of losartan, and losartan derivatives. Group: Biochemicals. Alternative Names: 5-(2-Fluorophenyl)-1-(triphenylmethyl)-1H-tetrazole. Grades: Highly Purified. CAS No. 937636-38-9. Pack Sizes: 100mg. US Biological Life Sciences.
Candesartan analog as angiotensin II antagonist. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid. Grades: Highly Purified. CAS No. 139481-72-4. Pack Sizes: 10mg. US Biological Life Sciences.
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N-Trityl Candesartan
N-Trityl Candesartan. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid. CAS No. 139481-72-4. Molecular Formula: C43H34N6O3. Mole Weight: 682.27. Catalog: APB139481724.
N-Trityl Candesartan
Cas No. 139481-72-4.
N-Trityl Candesartan Cilexetil
N-Trityl Candesartan Cilexetil is a titrylated impurity and precursor to Candesartan Cilexetil. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[ (Cyclohexyloxy) carbonyl]oxy]ethyl Ester; 2-Ethoxy-1- [ (2'- (1-tri tyl -1H-tetrazol-5-yl ) -1, 1'-biphenyl -4-yl ) methyl ] -7-benzimidazolecarboxyl ic Acid 1- (Cyclohexyl oxycarbonyl oxy) ethyl Ester. Grades: Highly Purified. CAS No. 170791-09-0. Pack Sizes: 100mg. US Biological Life Sciences.
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N-Trityl Candesartan Cilexetil Methoxy Analogue
Precursor to Candesartan Cilexetil Methoxy Analogues. Group: Biochemicals. Alternative Names: 2-Methoxy-1-[[2'-(N-trityl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[ (Cyclohexyloxy) carbonyl]oxy]ethyl Ester. Grades: Highly Purified. CAS No. 1246818-56-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Trityl Candesartan Ethyl Ester
Candesartan analog as angiotensin II antagonist. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 856414-35-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trityl Candesartan Methyl Ester-d4
An intermediate in the preparation of labeled Candesartan. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester-d4; 2-Ethoxy-1- [ (2'- (1-tri tyl -1H-tetrazol-5-yl ) -1, 1'-biphenyl -4-yl ) methyl ] -7-benzimidazolecarboxyl ic Acid Methyl Ester-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Precursor to Candesartan Cilexetil Methoxy Analogues. Group: Biochemicals. Alternative Names: 2-Methoxy-1-[[2'-(N-trityl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1246815-58-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
N-Trityl Des-4-hydroxy Olmesartan Medoxomil
N-Trityl Des-4-hydroxy Olmesartan Medoxomil is an impurity of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(prop-1-en-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carb. CAS No. 1227626-51-8. Molecular formula: C48H42N6O5. Mole weight: 782.88.
N-Trityl-deshydroxymethyl Losartan
Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 5-[4'-[(2-Butyl-4-chloro-1H-imidazol-1-yl)methyl][1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-1H-tetrazole. Grades: Highly Purified. CAS No. 1216502-96-3. Pack Sizes: 25mg. US Biological Life Sciences.
Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol; Trityllosartan. Grades: Highly Purified. CAS No. 124751-00-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan
N-Trityl Losartan. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Losartan Potassium Imp. H (EP) , [2-Butyl-4-chloro-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methanol, Losartan Imp. H (EP). CAS No. 133909-99-6. IUPAC Name: [2-butyl-5-chloro-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol. Molecular Formula: C41H37ClN6O. Mole Weight: 665.23. Catalog: APS133909996. SMILES: CCCCc1nc (Cl)c (CO)n1Cc2ccc (cc2)c3ccccc3c4nnn (n4)C (c5ccccc5) (c6ccccc6)c7ccccc7. Format: Neat.
Intermediate in the preparation of Losartan metabolites and impurities. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5- β-D-glucuronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan Carboxaldehyde
An intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 120568-18-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
N-Trityl losartan carboxylic acid
N-Trityl losartan carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Aci;N-Trityl Losartan Carboxylic Acid;2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imida. Product Category: Heterocyclic Organic Compound. CAS No. 947331-10-4. Molecular formula: C41H35ClN6O2. Mole weight: 679.208600 [g/mol]. Purity: 0.96. IUPACName: 2-butyl-5-chloro-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid. Canonical SMILES: CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)C(=O)O)Cl. Density: 1.25g/cm³. Product ID: ACM947331104. Alfa Chemistry ISO 9001:2015 Certified.
N-Trityl losartan carboxylic acid
N-Trityl losartan carboxylic acid. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid. Grades: Highly Purified. CAS No. 947331-10-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C41H35ClN6O2. US Biological Life Sciences.
Worldwide
N-Trityl Losartan-d3 Carboxaldehyde
A labeled intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-d3-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan-d3 Carboxylic Acid
A Losartan derivative for treatment of hypertension. Group: Biochemicals. Alternative Names: 2-Butyl-d3-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan-d4
A protected form of labeled Losartan (an antihypertensive). Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl-d4]-4-yl]methyl]-1H-imidazole-5-methanol; Trityllosartan-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan-d4 Carboxaldehyde
A labeled intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trityl Losartan Isomer
Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 2-Butyl-5-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-4-methanol. Grades: Highly Purified. CAS No. 133727-10-3. Pack Sizes: 25mg. US Biological Life Sciences.
N-Trityl-morpholinoguanine is an extensively studied and widely recognized biomedical compound, exhibiting as a formidable inhibitory compound against select enzymes intricately linked to the pivotal process of DNA synthesis. Synonyms: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-, (2R-cis)-. Grades: ≥95%. CAS No. 140679-49-8. Molecular formula: C29H28N6O3. Mole weight: 508.57.
N-Trityl-morpholino-T-5'-O-phosphoramidite
N-Trityl-morpholino-T-5'-O-phosphoramidite is an irreplaceable and significant compound, serving for facilitating the synthesis of oligonucleotides and DNA-modified compounds. Its extensive adoption within pharmaceutical research, dedicated to the innovation of studying diverse ailments such as cancer, genetic disorders and viral infections. Synonyms: 3- [ [di (propan-2-yl) amino] - [ [ (2S, 6R) -6- (5-methyl-2, 4-dioxopyrimidin-1-yl) -4-tritylmorpholin-2-yl] methoxy] phosphanyl] oxypropanenitrile; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[(2S,6R)-6-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-4-(triphenylmethyl)-2-morpholinyl]methyl ester. Grades: ≥95%. Molecular formula: C38H46N5O5P. Mole weight: 693.78.
N-Trityl-morpholino-U-5'-O-phosphoramidite
N-Trityl-morpholino-U-5'-O-phosphoramidite is a crucial component in the biomedical industry for the synthesis of phosphorothioate oligonucleotides. It finds applications in the development of drugs targeting various diseases like cancer, viral infections and genetic disorders. Synonyms: BP-29998; N-Trityl-morpholino-U-5'-O-phosphoramidite. Grades: ≥95%. Molecular formula: C37H44N5O5P. Mole weight: 669.75.
N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite is a compound, finding extensive employment in the esteemed realm of biomedical industry. This invaluable compound functions as a phosphoramidite compound, enabling the synthesis of nucleosides and nucleotides with tailored modifications. Its indispensible contribution lies in the facilitation of effective assembly of modified oligonucleotides that possess heightened properties and refined specificity. Synonyms: N-[9-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[(2S,6R)-6-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester. Grades: ≥95%. Molecular formula: C42H51N8O5P. Mole weight: 778.88.
N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite is a crucial compound used in the synthesis of oligonucleotide mimetics and modified nucleotides for biomedical research. It finds application in the development of novel drugs and therapies for studying various diseases, including cancer, viral infections and genetic disorders. Synonyms: N-[1-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]-2-oxopyrimidin-4-yl]benzamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl 2-cyanoethyl ester. Grades: ≥95%. Molecular formula: C44H49N6O5P. Mole weight: 772.87.
N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite is a crucial compound used in the biomedical industry for the efficient synthesis of oligonucleotides. This phosphoramidite derivative plays a vital role as a building block during solid-phase synthesis of DNA/RNA fragments, specifically for the research of genetic disorders, viral infections and various types of cancer. Synonyms: N-[9-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]purin-6-yl]benzamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl 2-cyanoethyl ester. Grades: ≥95%. Molecular formula: C45H49N8O4P. Mole weight: 796.90.
N-Trityl Olmesartan-d6 Ethyl Ester
N-Trityl Olmesartan-d6 Ethyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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N-Trityl Olmesartan Ethyl Ester
N-Trityl Olmesartan Ethyl Ester is an impurity of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid Ethyl Ester. CAS No. 172875-59-1. Molecular formula: C45H44N6O3. Mole weight: 716.87.
N-Trityl Olmesartan Ethyl Ester
N-Trityl Olmesartan Ethyl Ester. Group: Biochemicals. Alternative Names: 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 172875-59-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trityl Olmesartan Medoxomil Methyl Ether
N-Trityl Olmesartan Medoxomil Methyl Ether is an intermediate in the synthesis of Olmesartan Medoxomil (O550000), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Trityl Olmesartan Methyl Ketone
N-Trityl Olmesartan Methyl Ketone is an derivative of Olmesartan Medoxomil (O550000). Olmesartan Medoxomil is an angiotensin II receptor antagonist. Used as an anti-hypertensive agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trityl O-Methyl Ether Olmesartan Acid
N-Trityl O-Methyl Ether Olmesartan Acid is an intermediate in the synthesis of Olmesartan Acid (O550001), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
N-Trityl O-Methyl Ether Olmesartan Acid Ethyl Ester is an intermediate in the synthesis of Olmesartan Acid (O550001), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: Ethyl 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trityl-trimethylenediamine, polymer bound
N-Trityl-trimethylenediamine, polymer bound. Group: Biochemicals. Alternative Names: 1,3-Diaminopropane trityl resin; N- (3-Aminopropyl) tritylamine, polymer bound. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
N-Trityl-trimethylenediamine, polymer bound, 0.3-0.8 meq/g (substitution). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
N type Bismuth(III) telluride
N type Bismuth(III) telluride. Group: Semiconductor blocks. CAS No. 1304-82-1.
nTZDpa
nTZDpa. Group: Biochemicals. Grades: Purified. CAS No. 118414-59-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NU1025
NU1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1025 enhanced the cytotoxicity of the DNA-methylating agent MTIC, gamma-irradiation and bleomycin 3.5-, 1.4- and 2-fold respectively. Synonyms: NU-1025; NU 1025; 8-Hydroxy-2-methylquinazoline-4-one; NSC 696807. Grades: ≥98%. CAS No. 90417-38-2. Molecular formula: C9H8N2O2. Mole weight: 176.17.
NU 1025
NU 1025. Group: Biochemicals. Grades: Purified. CAS No. 90417-38-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NU1064
NU1064 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which can potentiate the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1064 potentiated a sublethal concentration of a DNA methylating agent in a concentration-dependent manner. Synonyms: NU-1064; NU 1064; 4-Piperidinol, 1-butyl-4-(2-pyridyl)methyl-, acetate, dihydrochloride. Grades: 98%. CAS No. 63916-38-1. Molecular formula: C9H9N3O. Mole weight: 175.19.
NU1085
NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. It has been developed to potentiate the cytotoxicity of ionizing radiation and anticancer drugs. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: NU-1085; NU 1085; 2-(4-hydroxyphenyl)-1H-benzo[d]imidazole-7-carboxamide. Grades: 98%. CAS No. 188106-83-4. Molecular formula: C14H11N3O2. Mole weight: 253.26.
NU2058
NU2058 is a potent CDK inhibitor. which has CDK2 IC(50)=17 microM and CDK1 IC(50)=26 microM. Synonyms: NU2058; NU 2058; NU-2058; O(6)-Cyclohexylmethylguanine. Grades: 0.98. CAS No. 161058-83-9. Molecular formula: C12H17N5O. Mole weight: 247.3.
NU 2058
NU 2058. Group: Biochemicals. Grades: Purified. CAS No. 161058-83-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NU6027
NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner. NU6027 attenuated G2/M arrest following DNA damage, inhibited RAD51 focus formation and increased the cytotoxicity of the major classes of DNA-damaging anticancer cytotoxic therapy but not the antimitotic, paclitaxel. In A2780 cells sensitisation to cisplatin was greatest in cells with functional p53 and mismatch repair (MMR) and sensitisation to temozolomide was greatest in p53 mutant cells with functional MMR. Importantly, NU6027 was synthetically lethal when DNA single-strand break repair is impaired either through poly(ADP-ribose) polymerase (PARP) inhibition or defects in XRCC1. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and PARP inhibitors. It provides proof of concept data for clinical development of ATR inhibitors. Synonyms: NU-6027; NU 6027; 2,6-Diamino-4-(cyclohexylmethoxy)-5-nitrosopyrimidine; 6-(Cyclohexylmethoxy)-5-nitroso-2,4-pyrimidinediamine; 4-Cyclohexylmethoxy-2,6-diamino-5-nitrosopyrimidine; 4-Cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine. Grades: ≥98%. CAS No. 220036-08-8. Molecular formula: C11H17N5O2. Mole weight: 251.29.
NU 6102
NU 6102 is a potent inhibitor of CDK1 and CDK2 with Ki values of 9 and 6 nM and IC50 values of 9.5 and 5.4 nM, respectively. NU 6102 inhibits Cdk4 activity with IC50 value of 1.6 μM. Synonyms: NU-6102; NU6102; 4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]benzenesulfonamide. Grades: ≥95%. CAS No. 444722-95-6. Molecular formula: C18H22N6O3S. Mole weight: 402.5.
Potent CDK1/cyclin B (IC50 = 9.5nM) and CDK2/cyclin A3 (IC50 = 5.4nM) inhibitor. 1,000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6uM), DYRK1A (IC50 = 0.9uM), PDK1 (IC50 = 0.8uM) and ROCKII (IC50 = 0.6uM). Inhibits cell growth. Group: Biochemicals. Alternative Names: O6-Cyclohexylmethyl-2- (4-sulfamoylanilino) purine. Grades: Highly Purified. CAS No. 444722-95-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H22N6O3S, Molecular Weight: 402.5. US Biological Life Sciences.
Worldwide
NU6140
NU6140 is a cyclin-dependent kinase 2 (cdk2) inhibitor, and induces cell-cycle arrest at the G2-M phase. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Synonyms: Cdk2 inhibitor IV; NU 6140. Grades: 98%. CAS No. 444723-13-1. Molecular formula: C23H30N6O2. Mole weight: 422.53.