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(6R)-5,6,7,8-Tetrahydro-L-biopterin. Group: Biochemicals. Grades: Highly Purified. CAS No. 62989-33-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H15N5O3. US Biological Life Sciences.
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(6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl
Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences.
(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (6r-(6r*(1r*,2s*)))-chlorid;(6r)-tetrahydrobiopterinhydrochloride;5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinondihydro;sapropterinhydrochloride;sun0588;6R-BH4;(6R)-BH4 2HCL;[6R-[6R*(1R*,2S*)]]-2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-5,6,7,8-TETRAHYDRO-4(1H)-PTERIDINONE DIHYDROCHLORIDE. Product Category: Heterocyclic Organic Compound. CAS No. 69056-38-8. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17. Product ID: ACM69056388. Alfa Chemistry ISO 9001:2015 Certified. Categories: Sapropterin dihydrochloride.
Sapropterin dihydrochloride
Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Synonyms: BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride. Grades: >98%. CAS No. 69056-38-8. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17.
Tetrahydrobiopterin (THB) dihydrochloride
Tetrahydrobiopterin (THB) dihydrochloride is an activating Nitric Oxide Synthase (NOS)cofactor used in a variety of applications. The compound is also a known cofactor for the monooxygenases that hydroxylates phenylalanine, tyrosine, and tryptophan. Synthesis of THB has been documented to be the rate limiting step in the metabolism of phenylalanine and the biosynthesis of neurotransmiter amines. In mice, Quinolinic acid (sc-203226) induced convulsions were potentiated with Tetrahydrobiopterin dihydrochloride demonstrating that endogenous NO may be involved in stimulating the NMDA receptors. When hypertensive mice were fed THB, but were not introduced to hydralazine or tetrahydroneopterin, they displayed improved cardiac THB stores, phosphorylated phospholamban levels, and diastolic dysfunction. The compound has also been observed as an essential cofactor in the hydroxylation process in mammalian brains. Applications: An activating nos cofactor. Group: Coenzymes. Synonyms: (6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Purity: ≥98%. Mole weight: 314.17. Appearance: Powder. Form: Solid. (6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride; Tetrahydrobiopterin (THB) dihydrochloride; 69056-38-8. Cat No: COEC-024.
Tetrahydrocorticosterone
Tetrahydrocorticosterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[(3R,5R,8S,9S,10S,11S,13S,14S,17S)-3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone; (6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN 2HCL; 5BETA-PREGNANE-3A,11BETA,21-TRIOL-20-ONE; TH B; TETRAHYDRO COMPOUND B. Product Category: Steroidal Compounds. CAS No. 68-42-8. Molecular formula: C21H34O4. Mole weight: 350.49. Purity: 0.95. IUPACName: 1-[(3R,5R,8S,9S,10S,11S,13S,14S,17S)-3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone. Canonical SMILES: CC12CCC(CC1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O)O. Density: 1.18 g/cm³. ECNumber: 200-690-5. Product ID: ACM68428. Alfa Chemistry ISO 9001:2015 Certified.
Sapropterin Related Compound ((6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate)
An impurity of Sapropterin.Sapropterin is an cofactor for phenylalanine hydroxylase. Synonyms: 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-, [6S-[6R*(1S*,2R*)]]-, sulfate (1:x) (salt); (S)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(1H)-one sulfate (1:x); (6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate; [6S-[6R*(1S*,2R*)]]-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone sulfate (1:x) (salt); (6S)-Tetrahydro-L-biopterin sulfate salt. Grades: ≥95%. CAS No. 109784-74-9. Molecular formula: C9H15N5O3.xH2SO4. Mole weight: 241.25 (free base).
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