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| Product | Description | |
|---|---|---|
| (R)-Butaprost | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| (R)-Butaprost | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4978; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid methyl ester. Grades: ≥98%. CAS No. 69648-38-0. Molecular formula: C24H40O5. Mole weight: 408.6. |  |
| (R)-Butaprost | (R)-Butaprost. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Butaprostum; TR-4979. Product Category: Heterocyclic Organic Compound. CAS No. 69648-38-0. Molecular formula: C24H40O5. Mole weight: 408.5714. Purity: 0.96. IUPACName: methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,4R)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoate. Canonical SMILES: CCCC1(CCC1)C(CC=CC2C(CC(=O)C2CCCCCCC(=O)OC)O)O. Density: 1.105g/cm³. Product ID: ACM69648380. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (R)-Butaprost (free acid) | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid. Grades: ≥98%. CAS No. 215168-33-5. Molecular formula: C23H38O5. Mole weight: 394.6. | |
| Butaprost,free acid | Butaprost,free acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-BUTAPROST (FREE ACID);BUTAPROST (FREE ACID);9-OXO-11ALPHA, 16S-DIHYDROXY-17-CYCLOBUTYL-PROST-13E-EN-1-OIC ACID;9-OXO-11ALPHA, 16R-DIHYDROXY-17-CYCLOBUTYL-PROST-13E-EN-1-OIC ACID;(+/-)-15-DEOXY-16R-HYDROXY-17-CYCLOBUTYL PROSTAGLANDIN E1;(+/-)-15-DEOXY. Product Category: Heterocyclic Organic Compound. CAS No. 433219-55-7. Molecular formula: C23H38O5. Mole weight: 394.54. Product ID: ACM433219557. Alfa Chemistry ISO 9001:2015 Certified. | |
| Butaprost | Butaprost is a structural analog of PGE2 and a selective agonist for the EP2 receptor subtype. It binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor. Butaprost does not bind appreciably to any of the other murine EP receptors. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1; 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1. Grades: ≥95%. CAS No. 433219-55-7. Molecular formula: C23H38O5. Mole weight: 394.6. | |
| PF-04418948 | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Synonyms: PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948. Grades: 98%. CAS No. 1078166-57-0. Molecular formula: C23H20FNO5. Mole weight: 409.41. | |
| TG 4-155 | TG 4-155 is a high affinity and selective EP2 receptor antagonist (KB = 2.4 and 34.5 nM for EP2 and DP1 receptors, respectively) displaying >500-fold selectivity over other prostanoid receptors. TG 4-155 inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro. Synonyms: TG4-155; TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155; (2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1164462-05-8. Molecular formula: C23H26N2O4. Mole weight: 394.46. | |
| TG6-129 | TG6-129 is an antagonist of the EP2 receptor, suppressing PGE2-induced elevation of cAMP in cells expressing EP2 with IC50 value of 1.6 μM. It reduces the expression of COX-2, IL-1β, IL-12, IL-23, IL-6, and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages. Synonyms: SID 17503974; (E)-N-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl]carbamothioyl]-3-(4-fluorophenyl)prop-2-enamide. Grades: ≥98%. CAS No. 1164464-14-5. Molecular formula: C20H18FN5O3S3. Mole weight: 491.6. | |
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