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| Product | Description | |
|---|---|---|
| (S)-Scoulerine | (S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor. Group: Biochemicals. Alternative Names: (13aS)-5, 8, 13, 13a-tTtrahydro-3, 10-dimethoxy-6H-dibenzo[a, g]quinolizine-2, 9-diol; 3,10-Dimethoxy-13aα-berbine-2,9-diol; (S)-5, 8, 13, 13a-Tetrahydro-3, 10-dimethoxy-6H-Dibenzo[a, g]quinolizine-2, 9-diol; Scoulerine; (-)-Scoulerine; (S)-(-)-Scoulerine; Scoulerin; l-Scoulerine; Alkaloid HF 1, from Hunnemannia fumariaefolia. Grades: Highly Purified. CAS No. 6451-73-6. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| (S)-scoulerine 9-O-methyltransferase | The product of this reaction is a precursor for protoberberine alkaloids in plants. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.117. CAS No. 96380-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1716; (S)-scoulerine 9-O-methyltransferase; EC 2.1.1.117; 96380-65-3. Cat No: EXWM-1716. |  |
| S-Scoulerine | S-Scoulerine. Group: Biochemicals. Alternative Names: 5, 8, 13, 13a-Tetrahydro-3, 10-dimethoxy-6H-dibenzo[a, g]quinolizine-2, 9-diol; (+/-)-3,10-Dimethoxy-berbine-2,9-diol; (RS)-scoulerine. Grades: Highly Purified. CAS No. 6451-73-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C19H21NO4. US Biological Life Sciences. | Worldwide |
| pavine N-methyltransferase | The enzyme, isolated from the plant Thalictrum flavum, also methylates (R,S)-stylopine and (S)-scoulerine (11%) with lower activity (14% and 11%, respectively). Group: Enzymes. Synonyms: PavNMT. Enzyme Commission Number: EC 2.1.1.300. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1908; pavine N-methyltransferase; EC 2.1.1.300; PavNMT. Cat No: EXWM-1908. | |
| reticuline oxidase | Contains FAD. The enzyme from the plant Eschscholtzia californica binds the cofactor covalently. Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)-tetrahydroprotoberberines. The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. Group: Enzymes. Synonyms: BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Enzyme Commission Number: EC 1.21.3.3. CAS No. 152232-28-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1250; reticuline oxidase; EC 1.21.3.3; 152232-28-5; BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Cat No: EXWM-1250. | |
| (S)-cheilanthifoline synthase | A heme-thiolate enzyme (P-450) catalysing an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid cheilanthifoline from oxidative ring closure of adjacent phenolic and methoxy groups of scoulerine. Group: Enzymes. Synonyms: (S)-scoulerine oxidase (methylenedioxy-bridge-forming). Enzyme Commission Number: EC 1.14.21.2. CAS No. 138791-27-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1024; (S)-cheilanthifoline synthase; EC 1.14.21.2; 138791-27-2; (S)-scoulerine oxidase (methylenedioxy-bridge-forming). Cat No: EXWM-1024. | |
| Scoulerine | Scoulerine ((-)-Scoulerine), an isoquinoline alkaloid, is a potent antimitotic compound. Scoulerine is also an inhibitor of BACE1 ( -site amyloid precursor protein cleaving enzyme 1). Scoulerine inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Scoulerine; Discretamine. CAS No. 6451-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1255. |  |
| (S)-nandinine synthase | A cytochrome P-450 heme-thiolate enzyme catalysing an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid (S)-nandinine by the oxidative ring closure of adjacent phenolic and methoxy groups of (S)-scoulerine. cf. EC 1.14.21.2, (S)-cheilanthifoline synthase, which catalyses a similar reaction at the other side of the (S)-scoulerine molecule, forming (S)-cheilanthifoline. Group: Enzymes. Synonyms: CYP719A3. Enzyme Commission Number: EC 1.14.21.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1023; (S)-nandinine synthase; EC 1.14.21.12; CYP719A3. Cat No: EXWM-1023. | |
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