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| Product | Description | |
|---|---|---|
| [Pyr1]-Apelin-13 | [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. Uses: Scientific research. Group: Peptides. Alternative Names: [pGlu1]-Apelin-13. CAS No. 217082-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1033. |  |
| [Pyr1]-Apelin-13 | [Pyr1]-Apelin-13 is the highly potent pyroglutamylated form of apelin-13, which is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 0.37 nM. It is the major apelin form in human plasma and heart, which the N-terminal glutamine residue is cyclized to pyroglutamic acid. It exhibits higher APJ agonist potency than Apelin-13. It has antipyretic and vasoconstrictor effects in vitro and in vivo. It is widely used for studying APJ-mediated cellular and physiological functions both in cultures and in animals in vivo. It is reactive toward human, rat, bovine and murine species. Synonyms: [Pyr1]-Apelin-13; [Pyr1]-Apelin13; [Pyr1]-Apelin 13; 5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine; Pyroglutamated apelin-13; [pGlu1]-apelin-13. Grades: 98%. CAS No. 217082-60-5. Molecular formula: C69H108N22O16S. Mole weight: 1533.81. |  |
| [Pyr1]-Apelin-13 trifluoroacetate salt | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| (Glp1)-Apelin-13 trifluoroacetate salt | The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13, respectively. Synonyms: (pGlu1)Apelin-13; Pyr-Apelin-13; (Pyr1)Apelin-13; 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C69H108N22O16S·xCF3COOH. Mole weight: 1533.80. | |
| MM 54 | MM 54 is an apelin receptor antagonist with IC50 value of 93 nM. It can antagonize the inhibitory effect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Synonyms: MM-54; MM54; H-Cys(1)-Arg-Pro-Arg-Leu-Cys(1)-Lys-His-Cys(2)-Arg-Pro-Arg-Leu-Cys(2)-OH; L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteinyl-L-lysyl-L-histidyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteine (1->6),(9->14)-bis(disulfide). Grades: ≥95%. CAS No. 1313027-43-8. Molecular formula: C70H121N29O15S4. Mole weight: 1737.15. | |
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