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| Product | Description | |
|---|---|---|
| 1-Azakenpaullone | 1-Azakenpaullone (1-Akp) is a highly selective and ATP-competitive inhibitor of glycogen synthase kinase-3 β (GSK-3β) , with an IC 50 value of 18 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Akp. CAS No. 676596-65-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-59090. |  |
| 1-Azakenpaullone | 1-Azakenpaullone inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 μM, respectively). Synonyms: Azakenpaullone; 9-bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one; 14-bromo-3, 8, 18-triazatetracyclo[9.7.0.02, 7.012, 17]octadeca-1(11), 2(7), 3, 5, 12(17), 13, 15-heptaen-9-one. Grades: >98%. CAS No. 676596-65-9. Molecular formula: C15H10BrN3O. Mole weight: 328.169. |  |
| 1-Azakenpaullone | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| 1-Azakenpaullone | A selective inhibitor of glycogen synthase kinase-3b. Group: Biochemicals. Alternative Names: 9-Bromo-7, 12-di hydropyridoazepinoi ndol-6 (5H) -one; 9-Bromo-7, 12-dihydropyrido[3', 2':2, 3]azepino[4, 5-b]indol-6(5H)-one. Grades: Highly Purified. CAS No. 676596-65-9. Pack Sizes: 2.5mg, 5mg. US Biological Life Sciences. |  Worldwide |
| 1-Azakenpaullone - CAS 676596-65-9 | A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3?. Group: Fluorescence/luminescence spectroscopy. | |
| InSolution 1-Azakenpaullone - CAS 676596-65-9 | A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3&beta. Group: Fluorescence/luminescence spectroscopy. | |
| 3-[(4-Ethoxy-1,4-dioxobutyl)amino]-2-pyridinecarboxylic Acid Ethyl Ester | A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone. Group: Biochemicals. Alternative Names: 3-[(4-Ethoxy-4-oxobutanoyl)amino]-2-pyridinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 676596-61-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione | A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone derivatives. Group: Biochemicals. Alternative Names: 7,8-Dihydro-5H-pyrido[3,2-b]azepine-6,9-dione. Grades: Highly Purified. CAS No. 676596-63-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Kenpaullone | Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively). Uses: Reprogramming. Synonyms: NSC664704; NSC-664704; NSC 664704; 9-Bromopaullone; 1-azakenpaullone; Kenpaullone. Grades: 98%. CAS No. 142273-20-9. Molecular formula: C16H11BrN2O. Mole weight: 327.18. | |
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