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| Product | Description | |
|---|---|---|
| 1-Deoxy-D-xylulose 5-phosphate | 1-Deoxy-D-xylulose 5-phosphate is a biosynthetic precursor to isopentenyl pyrophosphate and other terpenoids in certain bacteria and plants. This compound has applications in research of anti-malaria treatments, given its role in the metabolic pathway of Plasmodium parasites, which cause malaria. Synonyms: Deoxyxylulose phosphate; DOXP; D-threo-2-Pentulose, 1-deoxy-, 5-(dihydrogen phosphate); 1-D-Deoxyxylulose-5-phosphate; 1-Deoxy-D-threo-pent-2-ulose 5-phosphate; Deoxyxylulose phosphate; DXP. CAS No. 190079-18-6. Molecular formula: C5H11O7P. Mole weight: 214.11. |  |
| 1-Deoxy-D-xylulose 5-phosphate sodium salt | 1-Deoxy-D-xylulose 5-phosphate sodium salt - an indispensable compound in the biomedical realm. Serving as an intermediary in the creation of vital substances within diverse biochemical pathways, this product assumes utmost importance. Its pivotal function lies in the biosynthesis of isoprenoid compounds characterized by antibacterial and antiparasitic attributes, including carotenoids and natural products. Envisaging potential therapeutic and prophylactic applications, it exhibits promise in combating infectious ailments. Synonyms: Deoxyxylulose phosphate sodium salt; DXP sodium salt; D-threo-2-Pentulose, 1-deoxy-, 5-(dihydrogen phosphate), sodium salt (1:2); D-threo-2-Pentulose, 1-deoxy-, 5-(dihydrogen phosphate), disodium salt. Grade: ≥98% by TLC. CAS No. 798554-58-2. Molecular formula: C5H9Na2O7P. Mole weight: 258.07. | |
| 1-deoxy-D-xylulose-5-phosphate reductoisomerase | The enzyme requires Mn2+, Co2+ or Mg2+ for activity, with the first being most effective. The enzyme from several eubacteria, including Escherichia coli, forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). The mechanism has been shown to be a retroaldol/aldol reaction. Group: Enzymes. Synonyms: DXP-reductoisomerase; 1-deoxy-D-xylulose-5-phosphate isomeroreductase; 2-C-methyl-D-erythritol 4-phosphate (MEP) synthase. Enzyme Commission Number: EC 1.1.1.267. CAS No. 210756-42-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0173; 1-deoxy-D-xylulose-5-phosphate reductoisomerase; EC 1.1.1.267; 210756-42-6; DXP-reductoisomerase; 1-deoxy-D-xylulose-5-phosphate isomeroreductase; 2-C-methyl-D-erythritol 4-phosphate (MEP) synthase. Cat No: EXWM-0173. |  |
| 1-deoxy-D-xylulose-5-phosphate synthase | Requires thiamine diphosphate. The enzyme forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Enzyme Commission Number: EC 2.2.1.7. CAS No. 202218-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2034; 1-deoxy-D-xylulose-5-phosphate synthase; EC 2.2.1.7; 202218-79-9; 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Cat No: EXWM-2034. | |
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase | An iron-sulfur protein that contains either a [3Fe-4S] or a [4Fe-4S] cluster. This enzyme forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase. This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts. The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and dimethylallyl diphosphate. Group: Enzymes. Synonyms: isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Enzyme Commission Number: EC 1.17.7.4. CAS No. 512789-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1099; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; EC 1.17.7.4; 512789-14-9; isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Cat No: EXWM-1099. | |
| pyridoxine 5'-phosphate synthase | In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72 (erythrose-4-phosphate dehydrogenase), EC 1.1.1.290 (4-phosphoerythronate dehydrogenase), EC 2.6.1.52 (phosphoserine transaminase), EC 1.1.1.262 (4-hydroxythreonine-4-phosphate dehydrogenase), EC 2.6.99.2 (pyridoxine 5'-phosphate synthase) and EC 1.4.3.5 (with pyridoxine 5'-phosphate as substrate). 1-Deoxy-D-xylulose cannot replace 1-deoxy-D-xylulose 5-phosphate as a substrate. Group: Enzymes. Synonyms: pyridoxine 5-phosphate phospho lyase; PNP synthase; PdxJ. Enzyme Commission Number: EC 2.6.99.2. CAS No. 230310-47-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2943; pyridoxine 5'-phosphate synthase; EC 2.6.99.2; 230310-47-1; pyridoxine 5-phosphate phospho lyase; PNP synthase; PdxJ. Cat No: EXWM-2943. | |
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