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1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Duvoglustat. CAS No. 19130-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14860.
1-Deoxynojirimycin
Inhibitor of glucosidase I (K = 2.1mM) and II (K = 7mM). Group: Biochemicals. Grades: Purified. CAS No. 19130-96-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C6H13NO4. US Biological Life Sciences.
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1-Deoxynojirimycin hydrochloride
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin can prevent the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells through inhibiting both α-glucosidase I and II. The IC50 values are ~2 μM. Phase II clinical development of duvoglustat for Glycogen storage disease type II is ongoing. Uses: Glycogen storage disease type ii. Synonyms: 1,5-Dideoxy-1,5-imino-D-sorbitol hydrochloride; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride; Duvoglustat hydrochloride; Moranoline hydrochloride; DNJ hydrochloride. Grades: 98%. CAS No. 73285-50-4. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
1-Deoxynojirimycin hydrochloride
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Duvoglustat hydrochloride. CAS No. 73285-50-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14860A.
1-Deoxynojirimycin hydrochloride 99+%
1-Deoxynojirimycin hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
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2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt
2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt, known for its immense significance in the biomedical field, represents an indispensible constituent. With its medicinal characteristics, it assumes a pivotal position in both biomedical scrutiny and the advancement of pharmaceutical agents. Synonyms: (2R,3R,4R,5S)-3,4,5-Tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine hydrochloride. CAS No. 72983-76-7. Molecular formula: C34H38ClNO4. Mole weight: 560.12.
2-O-a-D-Galactopyranosyl-1-deoxynojirimycin
2-O-a-D-Galactopyranosyl-1-deoxynojirimycin is an immensely influential compound, standing as a paramount and discerning force in inhibiting alpha-glucosidase enzymes. Synonyms: Galactosyl-DNJ. CAS No. 155168-05-1. Molecular formula: C12H23NO9. Mole weight: 325.31.
N-Methyl-1-deoxynojirimycin 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 69567-10-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
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1-Deoxy-L-idonojirimycin hydrochloride
It is an inhibitor of yeast a-glucosidase and used in the synthesis of 1-deoxynojirimycin (DNJ). Synonyms: DIJ; (2S,3R,4R,5S)-2-Hydroxymethyl-3,4,5-piperidinetriol hydrochloride; 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3R,4R,5S)-, hydrochloride (1:1). Grades: ≥98%. CAS No. 210223-32-8. Molecular formula: C6H14ClNO4. Mole weight: 199.63.
Duvoglustat Free Base
Duvoglustat Free Base is an alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Duvoglustat Free Base; BAY-h5595; BAY-h-5595; BAY-h 5595; 1-deoxynojirimycin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 19130-96-2. Molecular formula: C6H13NO4. Mole weight: 163.17. Purity: >98%. IUPACName: (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol. Canonical SMILES: O[C@@H]1[C@@H](CO)NC[C@H](O)[C@H]1O. Product ID: ACM19130962-1. Alfa Chemistry ISO 9001:2015 Certified.
N-Dodecyldeoxynojirimycin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-DODECYL-1-DEOXYNOJIRIMYCIN; N-dodecyldeoxynojirimycin. Product Category: Heterocyclic Organic Compound. CAS No. 79206-22-7. Molecular formula: C18H37NO4. Mole weight: 367.954. Purity: 0.96. IUPACName: (2R,3R,4R,5S)-1-dodecyl-2-(hydroxymethyl)piperidine-3,4,5-triol. Canonical SMILES: CCCCCCCCCCCCN1CC(C(C(C1CO)O)O)O.Cl. Density: 1.07g/cm³. Product ID: ACM79206227. Alfa Chemistry ISO 9001:2015 Certified.
N-(n-Nonyl)deoxynojirimycin
An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. A possible therapeutic agent for Gaucher disease. Group: Biochemicals. Alternative Names: (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol; N-Nonyl-1-deoxynojirimycin; N-Nonyldeoxynojirimycin; NNDNJ. Grades: Highly Purified. CAS No. 81117-35-3. Pack Sizes: 5mg. US Biological Life Sciences.
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OGT2378
OGT2378 is a GCS inhibitor (Glucosyl Ceramide Synthase Inhibitor) with potential anticancer activity. In murine models with melanoma, OGT2378 decreased tumor size, and showed no cytotoxic and apoptotic effects on MEB-4 melanomacells. Additionally, it has been reported that OGT2378 is biologically active, and a well tolerated agent in in vivo system. Synonyms: OGT-2378; OGT 2378; Sinbaglustat; N-Pentyl-L-ido-1-deoxynojirimycin; (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol. Grades: 98%. CAS No. 441061-33-2. Molecular formula: C11H23NO4. Mole weight: 233.30.
Deoxynojirimycin (DNJ)
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. Group: Biochemicals. Alternative Names: DNJ. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. Group: Biochemicals. Alternative Names: DNJ Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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