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| Product | Description | |
|---|---|---|
| 10-DEBC hydrochloride | 10-DEBC hydrochloride is a selective Akt inhibitor, with an IC 50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925681-41-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100654. |  |
| 10-DEBC hydrochloride | 10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34. |  |
| 10-DEBC hydrochloride | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences. |  Worldwide |
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