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PI3Kα/mTOR-IN-1 PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR (Kis= 10.6 nM and 12.5 nM for mTOR and PI3Kα, respectively). Synonyms: Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)-. CAS No. 1013098-90-2. Molecular formula: C16H18N6O. Mole weight: 310.35. BOC Sciences 10