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Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga , exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC 50 values of 0.30 mM and 0.38 mM in rat aorta [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 103-36-6. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-Y0121.
2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Duloxetine EP Impurity E; 2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthol hydrochloride (1:1); 1-Naphthalenol, 2-[3-(methylamino)-1-(2-thienyl)propyl]-, hydrochloride (1:1). Grades: ≥95%. CAS No. 1033719-36-6. Molecular formula: C18H20ClNOS. Mole weight: 333.87.
2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol is an impurity of Duloxetine (D721000), a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used in treatment of stress urinary incontinence. Group: Biochemicals. Grades: Highly Purified. CAS No. 1033719-36-6. Pack Sizes: 5mg. US Biological Life Sciences.
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IMS2186
IMS2186 is an anti-choroidal neovascularization (CNV) agent that inhibits angiogenesis upstream of VEGF. IMS2186 can arrest cancer cell cycle in G2/M phase, thus exerting anti-proliferation and anti-angiogenesis effects. IMS2186 has no intraocular toxicity and reduces the amount of eye leakage and diseased cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031206-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101990.
IMS 2186
IMS 2186 is an anti-proliferative and anti-angiogenic compound developed as an anti-choroidal neovascularization (anti-CNV) drug. It inhibits the cell cycle at G2 and the production of PGE2/TNF-&alpha. Uses: Anti-cnv drug. Synonyms: IMS2186; IMS-2186; 3-[1-(3-Hydroxy-4-methoxyphenyl)-meth-(E)-ylidene]-6-methyl-chroman-4-one. Grades: 99%. CAS No. 1031206-36-6. Molecular formula: C18H16O4. Mole weight: 296.32.
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