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| Product | Description | |
|---|---|---|
| 1- (5-Chloronaphthalene sulfonyl) -1H-hexahydro-1, 4-diazepine, hydrochloride | 1- (5-Chloronaphthalene sulfonyl) -1H-hexahydro-1, 4-diazepine, hydrochloride. Group: Biochemicals. Alternative Names: ML-9. Grades: Highly Purified. CAS No. 105637-50-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C15H18Cl2N2O2S. US Biological Life Sciences. |  Worldwide |
| ML-9 | ML-9 is a selective and potent inhibitor of Akt kinase , inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity [3]. ML-9 inhibits inhibits MLCK, PKA and PKC activity with K i values of 4, 32 and 54 μM, respectively [1]. ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 105637-50-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-100932. |  |
| ML 9 hydrochloride | ML 9 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 105637-50-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML-9 hydrochloride | ML-9 hydrochloride is a myosin light chain kinase (MLCK) inhibitor. It enhances the anticancer activity of docetaxel and may be used as an adjuvant to existing anticancer chemotherapy. It inhibits natural killer (NK) cell activity in a dose-dependent manner without affecting target cell binding. It inhibits insulin-induced translocation of both GLUT4 and GLUT1 in a dose-dependent manner. It also inhibits agonist-induced Ca2+ entry into endothelial cells and catecholamine secretion in intact and permeabilized chromaffin cells. It inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. It may be a new type of vascular relaxant. Uses: Ml-9 hydrochloride may be used as an adjuvant to existing anticancer chemotherapy. it may be a new type of vascular relaxant. Synonyms: ML9; ML-9; ML 9; ML9 Hydrochloride;ML 9 Hydrochloride; 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine HCl;1-(5-Chloronaphthalen-1-yl)sulfonyl-1,4-diazepane hydrochloride. Grades: 95%. CAS No. 105637-50-1. Molecular formula: C15H18Cl2N2O2S. Mole weight: 361.29. |  |
| Protein Kinase Inhibitor ML-9 (PKI) (1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) | Competitive inhibitor of several protein kinases wrt ATP. Group: Biochemicals. Alternative Names: 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. CAS No. 105637-50-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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